{
    "uniprot_canonical_ac": "A1YK02-1",
    "uniprot_ac": "A1YK02",
    "uniprot_id": "NUP75_DROME",
    "mass": {
        "chemical_mass": 76872.0,
        "monoisotopic_mass": 76872.0
    },
    "refseq": {
        "ac": "NP_611300",
        "name": "nucleoporin 75kD",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611300"
    },
    "gene_names": [
        {
            "name": "Nup75",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A1YK02",
            "id": "A1YK02"
        },
        {
            "name": "CG5733; Dmel\\CG5733; Nup 75; nup75",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611300",
            "id": "NP_611300"
        },
        {
            "name": "CG5733",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A1YK02",
            "id": "A1YK02"
        },
        {
            "name": "Nup75",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611300",
            "id": "NP_611300"
        }
    ],
    "protein_names": [
        {
            "name": "Nuclear pore complex protein Nup75",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "",
            "id": "A1YK02"
        },
        {
            "name": "75 KDa Nucleoporin",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A1YK02"
        },
        {
            "name": "CG5733-PA; Nup75-PA; nucleoporin 75",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611300",
            "id": "NP_611300"
        },
        {
            "name": "Nucleoporin Nup75",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A1YK02"
        },
        {
            "name": "Nucleoporin Nup85",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A1YK02"
        },
        {
            "name": "nucleoporin 75kD",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611300",
            "id": "NP_611300"
        }
    ],
    "function": [
        {
            "annotation": "Component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance (By similarity). Required for nuclear import of phosphorylated Mad via importin msk (PubMed:20547758). Has no role in classical nuclear localization signal (cNLS)-dependent nuclear import via importin-beta (PubMed:20547758). Facilitates the interaction between Nup93 and sec13 with msk (PubMed:20547758).",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1YK02",
                    "url": "https://www.uniprot.org/uniprot/A1YK02#function"
                },
                {
                    "database": "PubMed",
                    "id": "20547758",
                    "url": "https://glygen.org/publication/PubMed/20547758"
                },
                {
                    "database": "UniProtKB",
                    "id": "Q9BW27",
                    "url": "https://www.uniprot.org/uniprot/Q9BW27#function"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0080392",
            "recommended_name": {
                "id": "DOID:0080392",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0080392",
                "name": "nephrotic syndrome type 17",
                "description": "A familial nephrotic syndrome that has_material_basis_in by homozygous or compound heterozygous mutation in the NUP85 gene on chromosome 17q25."
            },
            "synonyms": [
                {
                    "id": "MONDO:0032580",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0032580",
                    "name": "nephrotic syndrome, type 17",
                    "description": ""
                },
                {
                    "id": "MONDO:0032580",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0032580",
                    "name": "NEPHROTIC SYNDROME, TYPE 17",
                    "description": ""
                },
                {
                    "id": "MONDO:0032580",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0032580",
                    "name": "NPHS17",
                    "description": ""
                },
                {
                    "id": "MIM:618176",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/618176",
                    "name": "Nephrotic syndrome 17",
                    "description": "Nephrotic syndrome 17"
                }
            ],
            "evidence": [
                {
                    "id": "0080392",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0080392"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Drosophila melanogaster",
            "taxid": 7227,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1YK02",
                    "url": "https://www.uniprot.org/uniprot/A1YK02"
                }
            ],
            "common_name": "Fruit fly"
        }
    ],
    "gene": [
        {
            "name": "Nup75",
            "url": "https://www.uniprot.org/uniprot/A1YK02",
            "locus": {
                "chromosome": "2R",
                "start_pos": 18164694,
                "end_pos": 18167140,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "FBgn0034310",
                        "url": "https://www.ensembl.org/id/FBgn0034310"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "FBgn0034310",
            "url": "https://bgee.org/?page=gene&gene_id=FBgn0034310",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "FBgn0034310",
            "url": "https://flybase.org/reports/FBgn0034310",
            "database": "FlyBase",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "37078",
            "url": "https://www.ncbi.nlm.nih.gov/gene/37078",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "A1YK02",
            "url": "https://www.ebi.ac.uk/intact/interactors/id:A1YK02*",
            "database": "IntAct",
            "categories": [
                "Other"
            ]
        },
        {
            "id": "IPR011502",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011502",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "dme:Dmel_CG5733",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG5733",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "ELMEWLN",
            "url": "https://omabrowser.org/oma/group/ELMEWLN/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3141715at2759",
            "url": "http://www.orthodb.org/?query=3141715at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13373",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13373",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR13373:SF21",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13373:SF21",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF07575",
            "url": "http://pfam.xfam.org/family/PF07575",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_A1YK02",
            "url": "http://purl.obolibrary.org/obo/PR_A1YK02",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "R-DME-159227",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159227",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-159230",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159230",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-159231",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159231",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-159236",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159236",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-3301854",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3301854",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-3371453",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3371453",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-4085377",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-4085377",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-4551638",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-4551638",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-4615885",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-4615885",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-5578749",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5578749",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-DME-9615933",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9615933",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "NP_611300",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_611300",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A1YK02",
            "url": "https://www.uniprot.org/uniprot/A1YK02",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A1YK02-1",
            "url": "https://www.uniprot.org/uniprot/A1YK02-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MSDSGVFAFELGDDLATRCGNTLTGVFVPGSRIALSAYRHVTHSSRDEPTENAGQVPVLIYMAQESTLFDEPVLRSVLAEANATFATLQQLGSRATRAEYVNISRAYRSIVRSCLEKLEQAKKSPEVQTDEARLQRLCDAIVVFYAAECLWHLFEILYIQSNQLVVPQLLDWARFHSPHAEDRATDLLLMGEEASESDDYWSIVKSLIMLGEIDVTRAVLSQNRKAGQTSFKAAEQILKSMPVYQEGYALQKFHSQWEFWHVDTERKIQSGLFATEPELEQLIRLVAGDSEQWDAGIKESQDFYEYLPGYLLFTKPTCKPFELKIAAAKWLNRWCLLRPEREQCSMNRMVSQLMDHDLRLFIYDAQKLNDTHWFSTHLIDLIHHCGQLKSYFDQNNIDLPALRHSMIYEYGSYLMTSHNMWQLGIDYLDCCKQEGQAAIELLLPRITLRSERQATKLINLARQRGLISVEREICKVLSKRSYDNERYGNALEWAIRSKDVLLVTAVADFILKHYSKTGCMLCPDTIANVGGRMFASPRLVFLSKYFEFYEFYRTRDFLSASELLVNLLESKITPDYFWPSLLIDSMPLLESKDPKIFAKETVAILHHIETDLVPIIERDVSKYGKHHTETVFKDYRVENVDEIMNLLRLACARNLARALIIENTLPVV",
        "length": 668,
        "header": "sp|A1YK02-1|NUP75_DROME Isoform 1 of Nuclear pore complex protein Nup75  OS=Drosophila melanogaster OX=7227 GN=Nup75 PE=2 SV=1 CANONICAL=A1YK02-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A1YK02-1",
            "url": "",
            "sequence": {
                "sequence": "MSDSGVFAFELGDDLATRCGNTLTGVFVPGSRIALSAYRHVTHSSRDEPTENAGQVPVLIYMAQESTLFDEPVLRSVLAEANATFATLQQLGSRATRAEYVNISRAYRSIVRSCLEKLEQAKKSPEVQTDEARLQRLCDAIVVFYAAECLWHLFEILYIQSNQLVVPQLLDWARFHSPHAEDRATDLLLMGEEASESDDYWSIVKSLIMLGEIDVTRAVLSQNRKAGQTSFKAAEQILKSMPVYQEGYALQKFHSQWEFWHVDTERKIQSGLFATEPELEQLIRLVAGDSEQWDAGIKESQDFYEYLPGYLLFTKPTCKPFELKIAAAKWLNRWCLLRPEREQCSMNRMVSQLMDHDLRLFIYDAQKLNDTHWFSTHLIDLIHHCGQLKSYFDQNNIDLPALRHSMIYEYGSYLMTSHNMWQLGIDYLDCCKQEGQAAIELLLPRITLRSERQATKLINLARQRGLISVEREICKVLSKRSYDNERYGNALEWAIRSKDVLLVTAVADFILKHYSKTGCMLCPDTIANVGGRMFASPRLVFLSKYFEFYEFYRTRDFLSASELLVNLLESKITPDYFWPSLLIDSMPLLESKDPKIFAKETVAILHHIETDLVPIIERDVSKYGKHHTETVFKDYRVENVDEIMNLLRLACARNLARALIIENTLPVV",
                "length": 668,
                "header": "sp|A1YK02-1|NUP75_DROME Isoform 1 of Nuclear pore complex protein Nup75  OS=Drosophila melanogaster OX=7227 GN=Nup75 PE=2 SV=1 CANONICAL=A1YK02-1"
            },
            "locus": {
                "chromosome": "2R",
                "start_pos": 18167071,
                "end_pos": 18164767,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "FBtr0086775",
                        "url": "https://www.ensembl.org/id/FBtr0086775"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "FBpp0085954",
                        "url": "https://www.ensembl.org/id/FBpp0085954"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "The genome sequence of Drosophila melanogaster.",
            "journal": "Science",
            "date": "2000",
            "authors": "Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Dietz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, WoodageT, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1YK02",
                    "url": "https://www.uniprot.org/uniprot/A1YK02"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "10731132",
                    "url": "https://glygen.org/publication/PubMed/10731132"
                }
            ]
        },
        {
            "title": "A Drosophila full-length cDNA resource.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Stapleton M, Carlson J, Brokstein P, Yu C, Champe M, George R, Guarin H, Kronmiller B, Pacleb J, Park S, Wan K, Rubin GM, Celniker SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1YK02",
                    "url": "https://www.uniprot.org/uniprot/A1YK02"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537569",
                    "url": "https://glygen.org/publication/PubMed/12537569"
                }
            ]
        },
        {
            "title": "Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.",
            "journal": "Genome Biol.",
            "date": "2002",
            "authors": "Misra S, Crosby MA, Mungall CJ, Matthews BB, Campbell KS, Hradecky P, Huang Y, Kaminker JS, Millburn GH, Prochnik SE, Smith CD, Tupy JL, Whitfied EJ, Bayraktaroglu L, Berman BP, Bettencourt BR, Celniker SE, de Grey AD, Drysdale RA, Harris NL, Richter J, Russo S, Schroeder AJ, Shu SQ, Stapleton M, Yamada C, Ashburner M, Gelbart WM, Rubin GM, Lewis SE",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1YK02",
                    "url": "https://www.uniprot.org/uniprot/A1YK02"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "12537572",
                    "url": "https://glygen.org/publication/PubMed/12537572"
                }
            ]
        },
        {
            "title": "Specific nucleoporin requirement for Smad nuclear translocation.",
            "journal": "Mol. Cell. Biol.",
            "date": "2010",
            "authors": "Chen X., Xu L.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A1YK02",
                    "url": "https://www.uniprot.org/uniprot/A1YK02"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "20547758",
                    "url": "https://glygen.org/publication/PubMed/20547758"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "dme:Dmel_CG5733",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+dme:Dmel_CG5733",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-DME-159227",
            "name": "Transport of the SLBP independent Mature mRNA",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159227",
            "resource": "Reactome",
            "description": "Transport of the SLBP independent Mature mRNA"
        },
        {
            "id": "R-DME-159230",
            "name": "Transport of the SLBP Dependant Mature mRNA",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159230",
            "resource": "Reactome",
            "description": "Transport of the SLBP Dependant Mature mRNA"
        },
        {
            "id": "R-DME-159231",
            "name": "Transport of Mature mRNA Derived from an Intronless Transcript",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159231",
            "resource": "Reactome",
            "description": "Transport of Mature mRNA Derived from an Intronless Transcript"
        },
        {
            "id": "R-DME-159236",
            "name": "Transport of Mature mRNA derived from an Intron-Containing Transcript",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-159236",
            "resource": "Reactome",
            "description": "Transport of Mature mRNA derived from an Intron-Containing Transcript"
        },
        {
            "id": "R-DME-3301854",
            "name": "Nuclear Pore Complex (NPC) Disassembly",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3301854",
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            "description": "Nuclear Pore Complex (NPC) Disassembly"
        },
        {
            "id": "R-DME-3371453",
            "name": "Regulation of HSF1-mediated heat shock response",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-3371453",
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            "description": "Regulation of HSF1-mediated heat shock response"
        },
        {
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            "name": "SUMOylation of SUMOylation proteins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-4085377",
            "resource": "Reactome",
            "description": "SUMOylation of SUMOylation proteins"
        },
        {
            "id": "R-DME-4551638",
            "name": "SUMOylation of chromatin organization proteins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-4551638",
            "resource": "Reactome",
            "description": "SUMOylation of chromatin organization proteins"
        },
        {
            "id": "R-DME-4615885",
            "name": "SUMOylation of DNA replication proteins",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-4615885",
            "resource": "Reactome",
            "description": "SUMOylation of DNA replication proteins"
        },
        {
            "id": "R-DME-5578749",
            "name": "Transcriptional regulation by small RNAs",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-5578749",
            "resource": "Reactome",
            "description": "Transcriptional regulation by small RNAs"
        },
        {
            "id": "R-DME-9615933",
            "name": "Postmitotic nuclear pore complex (NPC) reformation",
            "url": "https://www.reactome.org/PathwayBrowser/#R-DME-9615933",
            "resource": "Reactome",
            "description": "Postmitotic nuclear pore complex (NPC) reformation"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q4QQS8-1",
            "protein_name": "Nuclear pore complex protein Nup85",
            "gene_name": "Nup85",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MEELDCEPAVTWIPGVNSKKKQMCFDWGPGEMLLCETSFNKTDKSEKVPSCPFIYIIRKDVDVYSQILRKLFNESHGIFVGLQRLEEELSGKSRKAQLVRVSKNYRSVIRACMEEMHQVAIAAKDPASGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSDHPSKHESFWNLVTVLVLQGRLDEARQMLSKEADASPSSAGMCRVLGDLMRTMPILSPGNTQTLTELELKWQHWREECERHLQDNTFAANPHLESLCKIMLGDEATLLEQKELMSNWYHFLVTRLLYSNPTVKPTDLHLYAQSSLDMFLGGESSPEPLDNILMAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCRLLQSHNLYFGSNMREFLLLEYASGLFAHHSLWQLGVDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVGSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRLYGEKRFGDAASLLLSLMTSQIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLASRRPECGEPDAQRLQDDDIETTKVEMLRLALARNLARAIIREGSLEGS",
                "length": 656
            },
            "evidence": [
                {
                    "id": "A1YK02",
                    "url": "https://omabrowser.org/oma/group/A1YK02/",
                    "database": "OMA"
                }
            ],
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q8R480-1",
            "protein_name": "Nuclear pore complex protein Nup85",
            "gene_name": "Nup85",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MEELDCEPAVTWIPGVNSKKKQMCFDWGPGEMLLCETSFNQTGKSEKVPSCPFIYIIRKDVDVYSQILRKLFNESHGIFVGLQKIEEELSGKSRKAQLVRVSKNYRSVIRACMEEMHQVAIAAKDPASGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGGDNPSKHENFWDLVTVLVLQGRLDEARQMLAKEADANPSCAGMCRVLGDLMRTMPILSPGNTQTLTELELKWQHWREECERHLQDNTFAANPRLESLCKIMLGDEAALLEQKELLSNWYHFLVTRLLYSNPTVKPIDLHFYAQSSLDMFLGGESSPEPLDNILMAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCRLLQSHNLYFGSNMREFLLLEYASGLFAHHSLWQLGVDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVKSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGSAMMLSDRLTFLGKYREFHRLYGEKRFGDAASLLLSLMTSQIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLASGRPECGEPDAQRLQDDDIETTKVEMLRLALARNLARAIIREGSLEGS",
                "length": 656
            },
            "evidence": [
                {
                    "id": "A1YK02",
                    "url": "https://omabrowser.org/oma/group/A1YK02/",
                    "database": "OMA"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q9BW27-1",
            "protein_name": "Nuclear pore complex protein Nup85",
            "gene_name": "NUP85",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MEELDGEPTVTLIPGVNSKKNQMYFDWGPGEMLVCETSFNKKEKSEMVPSCPFIYIIRKDVDVYSQILRKLFNESHGIFLGLQRIDEELTGKSRKSQLVRVSKNYRSVIRACMEEMHQVAIAAKDPANGRQFSSQVSILSAMELIWNLCEILFIEVAPAGPLLLHLLDWVRLHVCEVDSLSADVLGSENPSKHDSFWNLVTILVLQGRLDEARQMLSKEADASPASAGICRIMGDLMRTMPILSPGNTQTLTELELKWQHWHEECERYLQDSTFATSPHLESLLKIMLGDEAALLEQKELLSNWYHFLVTRLLYSNPTVKPIDLHYYAQSSLDLFLGGESSPEPLDNILLAAFEFDIHQVIKECSIALSNWWFVAHLTDLLDHCKLLQSHNLYFGSNMREFLLLEYASGLFAHPSLWQLGVDYFDYCPELGRVSLELHIERIPLNTEQKALKVLRICEQRQMTEQVRSICKILAMKAVRNNRLGSALSWSIRAKDAAFATLVSDRFLRDYCERGCFSDLDLIDNLGPAMMLSDRLTFLGKYREFHRMYGEKRFADAASLLLSLMTSRIAPRSFWMTLLTDALPLLEQKQVIFSAEQTYELMRCLEDLTSRRPVHGESDTEQLQDDDIETTKVEMLRLSLARNLARAIIREGSLEGS",
                "length": 656
            },
            "evidence": [
                {
                    "id": "A1YK02",
                    "url": "https://omabrowser.org/oma/group/A1YK02/",
                    "database": "OMA"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Cellular Component",
                "total": 2,
                "go_terms": [
                    {
                        "name": "nuclear pore outer ring",
                        "id": "GO:0031080",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031080",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1YK02",
                                "url": "https://www.uniprot.org/uniprot/A1YK02"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "nuclear membrane",
                        "id": "GO:0031965",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1YK02",
                                "url": "https://www.uniprot.org/uniprot/A1YK02"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 4,
                "go_terms": [
                    {
                        "name": "regulation of terminal button organization",
                        "id": "GO:2000331",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000331",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1YK02",
                                "url": "https://www.uniprot.org/uniprot/A1YK02"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mRNA export from nucleus",
                        "id": "GO:0006406",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006406",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1YK02",
                                "url": "https://www.uniprot.org/uniprot/A1YK02"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of DNA-templated transcription",
                        "id": "GO:0045893",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1YK02",
                                "url": "https://www.uniprot.org/uniprot/A1YK02"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein import into nucleus",
                        "id": "GO:0006606",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1YK02",
                                "url": "https://www.uniprot.org/uniprot/A1YK02"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "structural constituent of nuclear pore",
                        "id": "GO:0017056",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A1YK02",
                                "url": "https://www.uniprot.org/uniprot/A1YK02"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 102,
            "end_pos": 104,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 369,
            "end_pos": 371,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 82,
            "end_pos": 84,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycans",
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                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
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                {
                    "field": "n_linked_glycans",
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                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
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                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
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                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
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                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
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                    "field": "total",
                    "count": 0
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                {
                    "field": "total_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
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                    "field": "total",
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                {
                    "field": "total_sites",
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            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 4
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            ],
            "sort_fields": [
                "title",
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                "date",
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        }
    ]
}