{
    "uniprot_canonical_ac": "A0A571BEN1-1",
    "uniprot_ac": "A0A571BEN1",
    "uniprot_id": "A0A571BEN1_MOUSE",
    "mass": {
        "chemical_mass": 128025.0,
        "monoisotopic_mass": 128025.0
    },
    "refseq": {
        "ac": "NP_001239301",
        "name": "myosin-binding protein C, slow-type isoform 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301"
    },
    "gene_names": [
        {
            "name": "Mybpc1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A571BEN1",
            "id": "A0A571BEN1"
        },
        {
            "name": "8030451F13Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301",
            "id": "NP_001239301"
        },
        {
            "name": "8030451F13Rik",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprot/A0A571BEN1",
            "id": "A0A571BEN1"
        },
        {
            "name": "Mybpc1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301",
            "id": "NP_001239301"
        }
    ],
    "protein_names": [
        {
            "name": "Myosin binding protein C, slow-type",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A571BEN1"
        },
        {
            "name": "Slow-type C-protein; MyBP-C slow",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301",
            "id": "NP_001239301"
        },
        {
            "name": "myosin-binding protein C, slow-type isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301",
            "id": "NP_001239301"
        }
    ],
    "function": [
        {
            "annotation": "Fast and slow skeletal myosin binding protein-C and aging.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001239301",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301"
                },
                {
                    "database": "PubMed",
                    "id": "36409445",
                    "url": "https://glygen.org/publication/PubMed/36409445"
                }
            ]
        },
        {
            "annotation": "Sarcomeric deficits underlie MYBPC1-associated myopathy with myogenic tremor. Publication Status: Online-Only",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001239301",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301"
                },
                {
                    "database": "PubMed",
                    "id": "34437302",
                    "url": "https://glygen.org/publication/PubMed/34437302"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:0050646",
            "recommended_name": {
                "id": "DOID:0050646",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0050646",
                "name": "distal arthrogryposis",
                "description": "A muscle tissue disease characterized by congenital joint contractures of hand and feet."
            },
            "synonyms": [
                {
                    "id": "DOID:0050646",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0050646",
                    "name": "Arthrogryposis Multiplex Congenita",
                    "description": ""
                },
                {
                    "id": "MONDO:0007157",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007157",
                    "name": "arthrogryposis, distal, type 1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0007157",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007157",
                    "name": "arthrogryposis multiplex congenita",
                    "description": ""
                },
                {
                    "id": "MONDO:0007157",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007157",
                    "name": "AMC",
                    "description": ""
                },
                {
                    "id": "MONDO:0007157",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007157",
                    "name": "DA1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0007157",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007157",
                    "name": "arthrogryposis, distal, type 1A",
                    "description": ""
                },
                {
                    "id": "MONDO:0007157",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007157",
                    "name": "arthrogryposis multiplex congenita, distal, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007157",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007157",
                    "name": "arthrogryposis, distal, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007157",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007157",
                    "name": "arthrogryposis, distal, type 2B4",
                    "description": ""
                },
                {
                    "id": "MIM:108120",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/108120",
                    "name": "Arthrogryposis, distal, 1A",
                    "description": "Arthrogryposis, distal, 1A"
                }
            ],
            "evidence": [
                {
                    "id": "0050646",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0050646"
                }
            ]
        },
        {
            "disease_id": "DOID:0060654",
            "recommended_name": {
                "id": "DOID:0060654",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0060654",
                "name": "lethal congenital contracture syndrome 4",
                "description": "A lethal congenital contracture syndrome that has_material_basis_in homozygous mutation in the MYBPC1 gene on chromosome 12q23."
            },
            "synonyms": [
                {
                    "id": "MONDO:0013965",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013965",
                    "name": "lethal congenital contracture syndrome 4",
                    "description": "Any lethal congenital contracture syndrome in which the cause of the disease is a mutation in the MYBPC1 gene."
                },
                {
                    "id": "MONDO:0013965",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013965",
                    "name": "MYBPC1 lethal congenital contracture syndrome",
                    "description": ""
                },
                {
                    "id": "MONDO:0013965",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013965",
                    "name": "lethal congenital contracture syndrome 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013965",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013965",
                    "name": "lethal congenital contracture syndrome caused by mutation in MYBPC1",
                    "description": ""
                },
                {
                    "id": "MONDO:0013965",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013965",
                    "name": "lethal congenital contracture syndrome type 4",
                    "description": ""
                },
                {
                    "id": "MONDO:0013965",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013965",
                    "name": "LCCS4",
                    "description": ""
                },
                {
                    "id": "MIM:614915",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/614915",
                    "name": "Lethal congenital contracture syndrome 4",
                    "description": "Lethal congenital contracture syndrome 4"
                }
            ],
            "evidence": [
                {
                    "id": "0060654",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0060654"
                }
            ]
        },
        {
            "disease_id": "DOID:0081337",
            "recommended_name": {
                "id": "DOID:0081337",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0081337",
                "name": "congenital myopathy",
                "description": "A myopathy that is characterized by hypotonia and weakness, usually present from birth."
            },
            "synonyms": [],
            "evidence": [
                {
                    "id": "0081337",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081337"
                }
            ]
        },
        {
            "disease_id": "DOID:0081348",
            "recommended_name": {
                "id": "DOID:0081348",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0081348",
                "name": "congenital myopathy 16",
                "description": "A congenital myopathy that is characterized by onset of hypotonia and tremor in infancy and that has_material_basis_in heterozygous mutation in the MYBPC1 gene on chromosome 12q23. Patients have mildly delayed walking, unsteady gait, proximal muscle weakness, and a high-frequency tremor of the limbs."
            },
            "synonyms": [
                {
                    "id": "MONDO:0032797",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0032797",
                    "name": "myopathy, congenital, with tremor",
                    "description": ""
                },
                {
                    "id": "MONDO:0032797",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0032797",
                    "name": "MYOPATHY, CONGENITAL, WITH TREMOR",
                    "description": ""
                },
                {
                    "id": "MONDO:0032797",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0032797",
                    "name": "MYOTREM",
                    "description": ""
                },
                {
                    "id": "MONDO:0032797",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0032797",
                    "name": "Myogenic Tremor",
                    "description": ""
                },
                {
                    "id": "MIM:618524",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/618524",
                    "name": "Congenital myopathy 16",
                    "description": "Congenital myopathy 16"
                }
            ],
            "evidence": [
                {
                    "id": "0081348",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0081348"
                }
            ]
        },
        {
            "disease_id": "DOID:0111598",
            "recommended_name": {
                "id": "DOID:0111598",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:0111598",
                "name": "distal arthrogryposis type 1B",
                "description": "A distal arthrogryposis type 1 that has_material_basis_in heterozygous mutation in the MYBPC1 gene on chromosome 12q23.2."
            },
            "synonyms": [
                {
                    "id": "DOID:0111598",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:0111598",
                    "name": "DA1B",
                    "description": ""
                },
                {
                    "id": "MONDO:0013698",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013698",
                    "name": "arthrogryposis, distal, type 1B",
                    "description": ""
                },
                {
                    "id": "MONDO:0013698",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013698",
                    "name": "arthrogryposis, distal, type 1B",
                    "description": ""
                },
                {
                    "id": "MONDO:0013698",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0013698",
                    "name": "DA1B",
                    "description": ""
                },
                {
                    "id": "MIM:614335",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/614335",
                    "name": "Arthrogryposis, distal, 1B",
                    "description": "Arthrogryposis, distal, 1B"
                }
            ],
            "evidence": [
                {
                    "id": "0111598",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:0111598"
                }
            ]
        },
        {
            "disease_id": "DOID:1682",
            "recommended_name": {
                "id": "DOID:1682",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:1682",
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                "description": ""
            },
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                {
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                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1682",
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                    "description": ""
                },
                {
                    "id": "DOID:1682",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1682",
                    "name": "Congenital anomaly of heart",
                    "description": ""
                },
                {
                    "id": "DOID:1682",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1682",
                    "name": "Heart Malformation",
                    "description": ""
                },
                {
                    "id": "DOID:1682",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1682",
                    "name": "congenital heart defect",
                    "description": ""
                },
                {
                    "id": "DOID:1682",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1682",
                    "name": "heart defect",
                    "description": ""
                }
            ],
            "evidence": [
                {
                    "id": "1682",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:1682"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
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            "url": "https://www.uniprot.org/uniprot/A0A571BEN1",
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        },
        {
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        },
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        {
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        {
            "id": "R-MMU-390522",
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    ],
    "sequence": {
        "sequence": "MPEPTKKEENEVSAPAPPPEEWSLGESPAGGEEQDKQNANSQLSTLFVEKPQTGSVKVGANITFVAKVRAEDLLRKPTVKWFKGKWMDLASKAGKHLQLKETFERQTRVYTFEMQIIKAKENYAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPEIDVWELLKNANPNEYEKIAFQYGITDLRGMLKRLKRMRRVEKKSAAFAKILDPAYQVDKGGKVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNERIMFINNCSLTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDMNAYCGERVEMEVEVSEDDANVKWFKNGEEIFPGPKSRYKIKVEGKKHTLIIEGATKADSAEYSAMTTGGQSSAKLSVDLRPLKITTPLTDQTVKLGKEVCLKCEISENVPGKWTKNGLPVQEGERLKVVHKGRIHKLVIANALIEDEGEYVFTPDAYNVPLSAKVHVIDPPKIILDGLDADNTVTVIAGSKLRLEIPVTGEPPPKAIWSRADKAIMEGSGRIRAESYPDSSTLVIDVAERDDSGVYNINLKNEAGEAHASIKIKVVDIPDPPVAPNVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSKPFVPLAVTSPPTLLAVDSVTDSSVTMKWRPPDQIGAAGLDGYVLEYCFEGTEDWIVANTDLIDKTKFTINGLPTDAKIFVRVKAINAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGEEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKYVENASIDIQIVDRPGPPQTVTIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTNATITELVIGNEYYFRVFAENMCGLSEDATMTKESAVIAKDGKIYKNPVYEDFNFTEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKGGLSFCRLLLQGVPPNIIDSYLRDLQSSNPEEY",
        "length": 1139,
        "header": "tr|A0A571BEN1-1|A0A571BEN1_MOUSE Isoform 1 of Myosin binding protein C, slow-type  OS=Mus musculus OX=10090 GN=Mybpc1 PE=1 SV=1 CANONICAL=A0A571BEN1-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A571BEN1-1",
            "url": "",
            "sequence": {
                "sequence": "MPEPTKKEENEVSAPAPPPEEWSLGESPAGGEEQDKQNANSQLSTLFVEKPQTGSVKVGANITFVAKVRAEDLLRKPTVKWFKGKWMDLASKAGKHLQLKETFERQTRVYTFEMQIIKAKENYAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPEIDVWELLKNANPNEYEKIAFQYGITDLRGMLKRLKRMRRVEKKSAAFAKILDPAYQVDKGGKVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNERIMFINNCSLTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDMNAYCGERVEMEVEVSEDDANVKWFKNGEEIFPGPKSRYKIKVEGKKHTLIIEGATKADSAEYSAMTTGGQSSAKLSVDLRPLKITTPLTDQTVKLGKEVCLKCEISENVPGKWTKNGLPVQEGERLKVVHKGRIHKLVIANALIEDEGEYVFTPDAYNVPLSAKVHVIDPPKIILDGLDADNTVTVIAGSKLRLEIPVTGEPPPKAIWSRADKAIMEGSGRIRAESYPDSSTLVIDVAERDDSGVYNINLKNEAGEAHASIKIKVVDIPDPPVAPNVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSKPFVPLAVTSPPTLLAVDSVTDSSVTMKWRPPDQIGAAGLDGYVLEYCFEGTEDWIVANTDLIDKTKFTINGLPTDAKIFVRVKAINAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGEEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKYVENASIDIQIVDRPGPPQTVTIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTNATITELVIGNEYYFRVFAENMCGLSEDATMTKESAVIAKDGKIYKNPVYEDFNFTEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKGGLSFCRLLLQGVPPNIIDSYLRDLQSSNPEEY",
                "length": 1139,
                "header": "tr|A0A571BEN1-1|A0A571BEN1_MOUSE Isoform 1 of Myosin binding protein C, slow-type  OS=Mus musculus OX=10090 GN=Mybpc1 PE=1 SV=1 CANONICAL=A0A571BEN1-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 88440787,
                "end_pos": 88354334,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000238199.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000238199.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000158844.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000158844.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "D3YU50-1",
            "url": "",
            "sequence": {
                "sequence": "MPEPTKKEENEVSAPAPPPEEWSLGESPAGGEEQDKQNANSQLSTLFVEKPQTGSVKVGANITFVAKVRAEDLLRKPTVKWFKGKWMDLASKAGKHLQLKETFERQTRVYTFEMQIIKAKENYAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPEIDVWELLKNANPNEYEKIAFQYGITDLRGMLKRLKRMRRVEKKSAAFAKILDPAYQVDKGGKVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNERIMFINNCSLTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDMNAYCGERVEMEVEVSEDDANVKWFKNGEEIFPGPKSRYKIKVEGKKHTLIIEGATKADSAEYSAMTTGGQSSAKLSVDLRPLKITTPLTDQTVKLGKEVCLKCEISENVPGKWTKNGLPVQEGERLKVVHKGRIHKLVIANALIEDEGEYVFTPDAYNVPLSAKVHVIDPPKIILDGLDADNTVTVIAGSKLRLEIPVTGEPPPKAIWSRADKAIMEGSGRIRAESYPDSSTLVIDVAERDDSGVYNINLKNEAGEAHASIKIKVVDIPDPPVAPNVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSKPFVPLAVTSPPTLLAVDSVTDSSVTMKWRPPDQIGAAGLDGYVLEYCFEGTEDWIVANTDLIDKTKFTINGLPTDAKIFVRVKAINAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGEEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKYVENASIDIQIVDRPGPPQTVTIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTNATITELVIGNEYYFRVFAENMCGLSEDATMTKESAVIAKDGKIYKNPVYEDFNFTEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIYQGVNTPGQPVSLEGQQQS",
                "length": 1127,
                "header": "tr|D3YU50-1|A0A571BEN1_MOUSE Computationally mapped isoform of Myosin binding protein C, slow-type  OS=Mus musculus OX=10090 GN=Mybpc1 PE=1 SV=1 CANONICAL=A0A571BEN1-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 88440787,
                "end_pos": 88355803,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000119185.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000119185.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000112699.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000112699.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F6RQD1-1",
            "url": "",
            "sequence": {
                "sequence": "XFKNGEEIFPGPKSRYKIKVEGKKHTLIIEGATKADSAEYSAMTTGGQSSAKLSVDLRPLKITTPLTDQTVKLGKEVCLKCEISENVPGKWTKNGLPVQEGERLKVVHKGRIHKLVIANALIEDEGEYVFTPDAYNVPLSAKVHVIDPPKIILDGLDADNTVTVIAGSKLRLEIPVTGEPPPKAIWSRADKAIMEGSGRIRAESYPDSSTLVIDVAERDDSGVYNINLKNEAGEAHASIKIKVVDIPDPPVAPNVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSKPFVPLAVTSPPTLLAVDSVTDSSVTMKWRPPDQIGAAGLDGYVLEYCFEGSTSAKQSNENGETACDLPAEDWIVANTDLIDKTKFTINGLPTDAKIFVRVKAINAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGEEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKYVENASIDIQIVDRPGPPQTVTIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTNATITELVIGN",
                "length": 626,
                "header": "tr|F6RQD1-1|A0A571BEN1_MOUSE Computationally mapped isoform of Myosin binding protein C, slow-type  OS=Mus musculus OX=10090 GN=Mybpc1 PE=1 SV=1 CANONICAL=A0A571BEN1-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 88389284,
                "end_pos": 88362235,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000156573.2",
                        "url": "https://www.ensembl.org/id/ENSMUST00000156573.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000119024.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000119024.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "F7D574-1",
            "url": "",
            "sequence": {
                "sequence": "XEDWIVANTDLIDKTKFTINGLPTDAKIFVRVKAINAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGEEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKYVENASIDIQIVDRPGPPQTVTIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTNATITELVIGNEYYFRVFAENMCGLSEDATMTKESAVIAKDGKIYKNPVYEDFNFTEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKASD",
                "length": 362,
                "header": "tr|F7D574-1|A0A571BEN1_MOUSE Computationally mapped isoform of Myosin binding protein C, slow-type  OS=Mus musculus OX=10090 GN=Mybpc1 PE=1 SV=1 CANONICAL=A0A571BEN1-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 88372344,
                "end_pos": 88355555,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000153964.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000153964.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000122472.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000122472.2"
                    }
                ]
            }
        },
        {
            "isoform_ac": "Q6P6L5-1",
            "url": "",
            "sequence": {
                "sequence": "MPEPTKKEENEVSAPAPPPEEPNKEKEAGTAPAKEWSLGESPAGGEEQDKQNANSQLSTLFVEKPQTGSVKVGANITFVAKVRAEDLLRKPTVKWFKGKWMDLASKAGKHLQLKETFERQTRVYTFEMQIIKAKENYAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPEIDVWELLKNANPNEYEKIAFQYGITDLRGMLKRLKRMRRVEKKSAAFAKILDPAYQVDKGGKVRFVVELADPKLEVKWFKNGQEIRPSTKYIFEHKGNERIMFINNCSLTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDMNAYCGERVEMEVEVSEDDANVKWFKNGEEIFPGPKSRYKIKVEGKKHTLIIEGATKADSAEYSAMTTGGQSSAKLSVDLRPLKITTPLTDQTVKLGKEVCLKCEISENVPGKWTKNGLPVQEGERLKVVHKGRIHKLVIANALIEDEGEYVFTPDAYNVPLSAKVHVIDPPKIILDGLDADNTVTVIAGSKLRLEIPVTGEPPPKAIWSRADKAIMEGSGRIRAESYPDSSTLVIDVAERDDSGVYNINLKNEAGEAHASIKIKVVDIPDPPVAPNVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSKPFVPLAVTSPPTLLAVDSVTDSSVTMKWRPPDQIGAAGLDGYVLEYCFEGTEDWIVANTDLIDKTKFTINGLPTDAKIFVRVKAINAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGEEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKYVENASIDIQIVDRPGPPQTVTIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTNATITELVIGNEYYFRVFAENMCGLSEDATMTKESAVIAKDGKIYKNPVYEDFNFTEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVVAQ",
                "length": 1124,
                "header": "tr|Q6P6L5-1|A0A571BEN1_MOUSE Computationally mapped isoform of Myosin binding protein C, slow-type  OS=Mus musculus OX=10090 GN=Mybpc1 PE=1 SV=1 CANONICAL=A0A571BEN1-1"
            },
            "locus": {
                "chromosome": "10",
                "start_pos": 88440787,
                "end_pos": 88355795,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000121629.8",
                        "url": "https://www.ensembl.org/id/ENSMUST00000121629.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000112615.2",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000112615.2"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Sarcomeric deficits underlie MYBPC1-associated myopathy with myogenic tremor.",
            "journal": "JCI insight",
            "date": "2021",
            "authors": "Geist Hauserman J, Stavusis J, Joca HC, Robinett JC, Hanft L, Vandermeulen J, Zhao R, Stains JP, Konstantopoulos K, McDonald KS, Ward C, Kontrogianni-Konstantopoulos A",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001239301",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34437302",
                    "url": "https://glygen.org/publication/PubMed/34437302"
                }
            ]
        },
        {
            "title": "Fast and slow skeletal myosin binding protein-C and aging.",
            "journal": "GeroScience",
            "date": "2022-11-21",
            "authors": "Perazza L R, Wei G, Thompson L V",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001239301",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001239301"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "36409445",
                    "url": "https://glygen.org/publication/PubMed/36409445"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:109272",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:109272",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-MMU-390522",
            "name": "Striated Muscle Contraction",
            "url": "https://www.reactome.org/PathwayBrowser/#R-MMU-390522",
            "resource": "Reactome",
            "description": "Striated Muscle Contraction"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "Q00872-1",
            "protein_name": "Myosin-binding protein C, slow-type",
            "gene_name": "MYBPC1",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ",
                "length": 1141
            },
            "evidence": [
                {
                    "id": "45233305",
                    "url": "http://www.informatics.jax.org/homology/45233305",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q63518-1",
            "protein_name": "Myosin-binding protein C, slow-type",
            "gene_name": "Mybpc1",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "EEIVPGPKSRYRIKVEGKKHTLIIEGATKADSAEYSVMTTGGQSSAKLSVDLRPLKITTPLTDQTVKLGKEVCLKCEISENVPGKWTKNGLPVQEGERLKVVHKGRIHKLVIANALIEDEGEYVFTPDAITVPLVCQIHVIDPPKIILDGLEADNTVTVIAGSKLRLEIPVTGEPPPKAIWSRADKAIMEGSGRIRAESYPDSSTLVIDVAERDDSGVYNINLKNEAGEAHASIKLRLWISLILRLAPNVTEVGDDWCIMNWEPPVYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSKPFVPLAVTSPPTLLAVDSVTDSSVTMKWRPPDQIGAAGLSGYVLEYCFEGSTSAKQSNENGEAANDLPAEDWSLQTQTGSTRPKFTITGLPTDAKIFVRVKAINAAGASETKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLEVKVDKYVENASIDIQIVDRPGPPQAVTIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFAVIEHYHRTNATITELVIGN",
                "length": 621
            },
            "evidence": [
                {
                    "id": "45233305",
                    "url": "http://www.informatics.jax.org/homology/45233305",
                    "database": "MGI"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "structural constituent of cytoskeleton",
                        "id": "GO:0005200",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005200",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A571BEN1",
                                "url": "https://www.uniprot.org/uniprot/A0A571BEN1"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "myosin binding",
                        "id": "GO:0017022",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017022",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A571BEN1",
                                "url": "https://www.uniprot.org/uniprot/A0A571BEN1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "cytoskeleton",
                        "id": "GO:0005856",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A571BEN1",
                                "url": "https://www.uniprot.org/uniprot/A0A571BEN1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Biological Process",
                "total": 1,
                "go_terms": [
                    {
                        "name": "muscle contraction",
                        "id": "GO:0006936",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006936",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A571BEN1",
                                "url": "https://www.uniprot.org/uniprot/A0A571BEN1"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 1011,
            "end_pos": 1013,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 1032,
            "end_pos": 1034,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 1036,
            "end_pos": 1038,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 300,
            "end_pos": 302,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 614,
            "end_pos": 616,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 61,
            "end_pos": 63,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 890,
            "end_pos": 892,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 958,
            "end_pos": 960,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
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