{
    "uniprot_canonical_ac": "A0A0G2KAH7-1",
    "uniprot_ac": "A0A0G2KAH7",
    "uniprot_id": "A0A0G2KAH7_RAT",
    "mass": {
        "chemical_mass": 82019.0,
        "monoisotopic_mass": 82019.0
    },
    "refseq": {
        "ac": "NP_001101221",
        "name": "exostosin-2 isoform 2",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101221"
    },
    "gene_names": [
        {
            "name": "Ext2",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7",
            "id": "A0A0G2KAH7"
        },
        {
            "name": "Ext2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101221",
            "id": "NP_001101221"
        }
    ],
    "protein_names": [
        {
            "name": "Exostosin glycosyltransferase 2",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "",
            "id": "A0A0G2KAH7"
        },
        {
            "name": "exostoses (multiple) 2; exostosin 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101221",
            "id": "NP_001101221"
        },
        {
            "name": "exostosin-2 isoform 2",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101221",
            "id": "NP_001101221"
        }
    ],
    "function": [
        {
            "annotation": "Ext2 gene is involved in heparan sulfate proteoglycans metabolism.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001101221",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101221"
                },
                {
                    "database": "PubMed",
                    "id": "22339633",
                    "url": "https://glygen.org/publication/PubMed/22339633"
                }
            ]
        }
    ],
    "disease": [
        {
            "disease_id": "DOID:206",
            "recommended_name": {
                "id": "DOID:206",
                "resource": "Disease Ontology",
                "url": "http://disease-ontology.org/term/DOID:206",
                "name": "hereditary multiple exostoses",
                "description": "An exostosis that has_material_basis_in a mutation on the genes EXT1, EXT2 and EXT3 which results in multiple bony spurs throughout a child's growth."
            },
            "synonyms": [
                {
                    "id": "DOID:206",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:206",
                    "name": "Multiple congenital exostosis",
                    "description": ""
                },
                {
                    "id": "DOID:206",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:206",
                    "name": "Multiple exostosis syndromes",
                    "description": ""
                },
                {
                    "id": "DOID:206",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:206",
                    "name": "Osteochondromatosis syndrome",
                    "description": ""
                },
                {
                    "id": "DOID:206",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:206",
                    "name": "hereditary multiple exostoses 1",
                    "description": ""
                },
                {
                    "id": "DOID:206",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:206",
                    "name": "hereditary multiple exostoses 2",
                    "description": ""
                },
                {
                    "id": "DOID:206",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:206",
                    "name": "hereditary multiple exostoses 3",
                    "description": ""
                },
                {
                    "id": "DOID:206",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:206",
                    "name": "multiple ostechondromas",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "exostoses, multiple, type 1",
                    "description": "Any exostoses, multiple in which the cause of the disease is a mutation in the EXT1 gene."
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "EXT1 exostoses, multiple",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "exostoses, multiple caused by mutation in EXT1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "exostoses, multiple, type 1",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "EXT",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "diaphyseal Aclasis",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "exostoses, multiple, type I",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "multiple cartilaginous exostoses",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "multiple osteochondromas",
                    "description": ""
                },
                {
                    "id": "MONDO:0007585",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007585",
                    "name": "osteochondromatosis",
                    "description": ""
                },
                {
                    "id": "MONDO:0007586",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007586",
                    "name": "exostoses, multiple, type 2",
                    "description": "This gene is involved in the heparin/heparin sulfate biosynthesis, cell organization/biogenesis and development of the cytoskeleton in chondrocytes."
                },
                {
                    "id": "MONDO:0007586",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007586",
                    "name": "EXT2 Gene",
                    "description": ""
                },
                {
                    "id": "MONDO:0007586",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007586",
                    "name": "EXT2 exostoses, multiple",
                    "description": ""
                },
                {
                    "id": "MONDO:0007586",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007586",
                    "name": "exostoses (Multiple) 2 Gene",
                    "description": ""
                },
                {
                    "id": "MONDO:0007586",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007586",
                    "name": "exostoses, multiple caused by mutation in EXT2",
                    "description": ""
                },
                {
                    "id": "MONDO:0007586",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007586",
                    "name": "exostoses, multiple, type 2",
                    "description": ""
                },
                {
                    "id": "MONDO:0007586",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007586",
                    "name": "Ext2",
                    "description": ""
                },
                {
                    "id": "MONDO:0007586",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0007586",
                    "name": "exostoses, multiple, type II",
                    "description": ""
                },
                {
                    "id": "MONDO:0010846",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010846",
                    "name": "exostoses, multiple, type III",
                    "description": ""
                },
                {
                    "id": "MONDO:0010846",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010846",
                    "name": "EXT3",
                    "description": ""
                },
                {
                    "id": "MONDO:0010846",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010846",
                    "name": "exostoses, multiple, type III",
                    "description": ""
                },
                {
                    "id": "MONDO:0010846",
                    "resource": "MONDO",
                    "url": "https://monarchinitiative.org/disease/MONDO:0010846",
                    "name": "exostoses, multiple, type 3",
                    "description": ""
                },
                {
                    "id": "MIM:133700",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/133700",
                    "name": "Hereditary multiple exostoses 1",
                    "description": "Hereditary multiple exostoses 1"
                },
                {
                    "id": "MIM:133701",
                    "resource": "MIM",
                    "url": "https://www.omim.org/entry/133701",
                    "name": "Hereditary multiple exostoses 2",
                    "description": "Hereditary multiple exostoses 2"
                }
            ],
            "evidence": [
                {
                    "id": "206",
                    "database": "Alliance of Genome Resources",
                    "url": "https://www.alliancegenome.org/disease/DOID:206"
                }
            ]
        }
    ],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Rattus norvegicus",
            "taxid": 10116,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A0G2KAH7",
                    "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                }
            ],
            "common_name": "Rat"
        }
    ],
    "gene": [
        {
            "name": "Ext2",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7",
            "locus": {
                "chromosome": "3",
                "start_pos": 79665415,
                "end_pos": 79798059,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSRNOG00000008944",
                        "url": "https://www.ensembl.org/id/ENSRNOG00000008944"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSRNOG00000008944",
            "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000008944",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "311215",
            "url": "https://www.ncbi.nlm.nih.gov/gene/311215",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR004263",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR004263",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR015338",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR015338",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR029044",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR040911",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR040911",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "rno:311215",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:311215",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "NCTFWDC",
            "url": "https://omabrowser.org/oma/group/NCTFWDC/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1220028at2759",
            "url": "http://www.orthodb.org/?query=1220028at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR48261",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR48261:SF2",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261:SF2",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF03016",
            "url": "http://pfam.xfam.org/family/PF03016",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF09258",
            "url": "http://pfam.xfam.org/family/PF09258",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-RNO-2022928",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2022928",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "1307707",
            "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1307707",
            "database": "RGD",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "A0A0G2KAH7",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A0G2KAH7-1",
            "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9PTT2",
            "url": "https://www.uniprot.org/uniprot/E9PTT2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "E9PTT2-1",
            "url": "https://www.uniprot.org/uniprot/E9PTT2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRSIREVPVVRLTADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSAISREYNELLTAISDSDYYTDDISRACLFVPSIDVLNQNPLRIKETAQALAQLPRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEVALPEKAPGSRRYFLLSSQMAIHPEYREELEALQAKHRESVLVLDKCTNLSEGVLSIRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVIPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFRSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL",
        "length": 718,
        "header": "tr|A0A0G2KAH7-1|A0A0G2KAH7_RAT Isoform 1 of Exostosin glycosyltransferase 2  OS=Rattus norvegicus OX=10116 GN=Ext2 PE=1 SV=1 CANONICAL=A0A0G2KAH7-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A0G2KAH7-1",
            "url": "",
            "sequence": {
                "sequence": "MCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRSIREVPVVRLTADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSAISREYNELLTAISDSDYYTDDISRACLFVPSIDVLNQNPLRIKETAQALAQLPRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEVALPEKAPGSRRYFLLSSQMAIHPEYREELEALQAKHRESVLVLDKCTNLSEGVLSIRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVIPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFRSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL",
                "length": 718,
                "header": "tr|A0A0G2KAH7-1|A0A0G2KAH7_RAT Isoform 1 of Exostosin glycosyltransferase 2  OS=Rattus norvegicus OX=10116 GN=Ext2 PE=1 SV=1 CANONICAL=A0A0G2KAH7-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 79788979,
                "end_pos": 79665934,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000083743.2",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000083743.2"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000075401.1",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000075401.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "E9PTT2-1",
            "url": "",
            "sequence": {
                "sequence": "MCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRSIREVPVVRLTADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSAISREYNELLTAISDSDYYTDDISRACLFVPSIDVLNQNPLRIKETAQALAQLPRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEVALPEKAPGSRRYFLLSSQMAIHPEYREELEALQAKHRESVLVLDKCTNLSEGVLSIRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVIPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFRSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL",
                "length": 670,
                "header": "tr|E9PTT2-1|A0A0G2KAH7_RAT Computationally mapped isoform of Exostosin glycosyltransferase 2  OS=Rattus norvegicus OX=10116 GN=Ext2 PE=1 SV=2 CANONICAL=A0A0G2KAH7-1"
            },
            "locus": {
                "chromosome": "3",
                "start_pos": 79788979,
                "end_pos": 79665934,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSRNOT00000012161.8",
                        "url": "https://www.ensembl.org/id/ENSRNOT00000012161.8"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSRNOP00000012161.5",
                        "url": "https://www.ensembl.org/id/ENSRNOP00000012161.5"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Expression of Ext1, Ext2, and heparanase genes in brain of senescence-accelerated OXYS rats in early ontogenesis and during development of neurodegenerative changes.",
            "journal": "Biochemistry. Biokhimiia",
            "date": "2012",
            "authors": "Shevelev OB, Rykova VI, Fedoseeva LA, Leberfarb EY, Dymshits GM, Kolosova NG",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001101221",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001101221"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "22339633",
                    "url": "https://glygen.org/publication/PubMed/22339633"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "rno:311215",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:311215",
            "resource": "KEGG Pathway"
        },
        {
            "id": "R-RNO-2022928",
            "name": "HS-GAG biosynthesis",
            "url": "https://www.reactome.org/PathwayBrowser/#R-RNO-2022928",
            "resource": "Reactome",
            "description": "HS-GAG biosynthesis"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "P70428-1",
            "protein_name": "Exostosin-2",
            "gene_name": "Ext2",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MCASVKSNIRGPALIPRMKTKHRIYYVTLFSIVLLGLIATGMFQFWPHSIESSSDGGVEKRSIREVPVVRLPTDSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYPLKKYVDDAGVPVSSAISREYNELLTAISDSDYYTDDINRACLFVPSIDVLNQNPLRIKETAQALAQLSRWDRGTNHLLFNMLPGAPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVFSPLSAEMALPEKAPGPRRYFLLSSQMAIHPEYREELEALQAKHQESVLVLDKCTNLSEGVLSVRKRCHQHQVFDYPQVLQEATFCTVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQNIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWASVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEESLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDTHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL",
                "length": 718
            },
            "evidence": [
                {
                    "id": "45226820",
                    "url": "http://www.informatics.jax.org/homology/45226820",
                    "database": "MGI"
                }
            ],
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "Q93063-1",
            "protein_name": "Exostosin-2",
            "gene_name": "EXT2",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MCASVKYNIRGPALIPRMKTKHRIYYITLFSIVLLGLIATGMFQFWPHSIESSNDWNVEKRSIRDVPVVRLPADSPIPERGDLSCRMHTCFDVYRCGFNPKNKIKVYIYALKKYVDDFGVSVSNTISREYNELLMAISDSDYYTDDINRACLFVPSIDVLNQNTLRIKETAQAMAQLSRWDRGTNHLLFNMLPGGPPDYNTALDVPRDRALLAGGGFSTWTYRQGYDVSIPVYSPLSAEVDLPEKGPGPRQYFLLSSQVGLHPEYREDLEALQVKHGESVLVLDKCTNLSEGVLSVRKRCHKHQVFDYPQVLQEATFCVVLRGARLGQAVLSDVLQAGCVPVVIADSYILPFSEVLDWKRASVVVPEEKMSDVYSILQSIPQRQIEEMQRQARWFWEAYFQSIKAIALATLQIINDRIYPYAAISYEEWNDPPAVKWGSVSNPLFLPLIPPQSQGFTAIVLTYDRVESLFRVITEVSKVPSLSKLLVVWNNQNKNPPEDSLWPKIRVPLKVVRTAENKLSNRFFPYDEIETEAVLAIDDDIIMLTSDELQFGYEVWREFPDRLVGYPGRLHLWDHEMNKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKMPGDIKNWVDAHMNCEDIAMNFLVANVTGKAVIKVTPRKKFKCPECTAIDGLSLDQTHMVERSECINKFASVFGTMPLKVVEHRADPVLYKDDFPEKLKSFPNIGSL",
                "length": 718
            },
            "evidence": [
                {
                    "id": "45226820",
                    "url": "http://www.informatics.jax.org/homology/45226820",
                    "database": "MGI"
                }
            ],
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 19,
                "go_terms": [
                    {
                        "name": "sulfation",
                        "id": "GO:0051923",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "polysaccharide biosynthetic process",
                        "id": "GO:0000271",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000271",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of blood pressure",
                        "id": "GO:0008217",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008217",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "vasodilation",
                        "id": "GO:0042311",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042311",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "heart contraction",
                        "id": "GO:0060047",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein N-linked glycosylation",
                        "id": "GO:0006487",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006487",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mesoderm formation",
                        "id": "GO:0001707",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001707",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ossification",
                        "id": "GO:0001503",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "chondrocyte differentiation",
                        "id": "GO:0002062",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002062",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glycosaminoglycan biosynthetic process",
                        "id": "GO:0006024",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006024",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "sodium ion homeostasis",
                        "id": "GO:0055078",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055078",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "heparin biosynthetic process",
                        "id": "GO:0030210",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030210",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "multicellular organismal-level water homeostasis",
                        "id": "GO:0050891",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050891",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "heparan sulfate proteoglycan biosynthetic process",
                        "id": "GO:0015012",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cellular response to fibroblast growth factor stimulus",
                        "id": "GO:0044344",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044344",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "gene expression",
                        "id": "GO:0010467",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "endochondral bone morphogenesis",
                        "id": "GO:0060350",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060350",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "fluid transport",
                        "id": "GO:0042044",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042044",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process",
                        "id": "GO:0015014",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015014",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 3,
                "go_terms": [
                    {
                        "name": "endoplasmic reticulum",
                        "id": "GO:0005783",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "Golgi apparatus",
                        "id": "GO:0005794",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "UDP-N-acetylglucosamine transferase complex",
                        "id": "GO:0043541",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043541",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 7,
                "go_terms": [
                    {
                        "name": "protein homodimerization activity",
                        "id": "GO:0042803",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "protein heterodimerization activity",
                        "id": "GO:0046982",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046982",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "acetylglucosaminyltransferase activity",
                        "id": "GO:0008375",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glycosyltransferase activity",
                        "id": "GO:0016757",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucuronosyltransferase activity",
                        "id": "GO:0015020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015020",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity",
                        "id": "GO:0050508",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050508",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity",
                        "id": "GO:0050509",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050509",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A0G2KAH7",
                                "url": "https://www.uniprot.org/uniprot/A0A0G2KAH7"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 288,
            "end_pos": 290,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 637,
            "end_pos": 639,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                },
                {
                    "field": "n_linked_glycans",
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                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
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                {
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
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                {
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                {
                    "field": "o_linked_glycans",
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                {
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            ],
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        {
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                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
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                {
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                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycan_sites",
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                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
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                    "count": 0
                },
                {
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            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
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                    "field": "total",
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                },
                {
                    "field": "total_sites",
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                }
            ],
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        },
        {
            "table_id": "snv_non_disease",
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                {
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            ],
            "sort_fields": []
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        {
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            ],
            "sort_fields": [
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        }
    ]
}