{ "uniprot_canonical_ac": "A0A0G2JX07-1", "uniprot_ac": "A0A0G2JX07", "uniprot_id": "A0A0G2JX07_RAT", "mass": { "chemical_mass": 42817.0, "monoisotopic_mass": 42817.0 }, "refseq": {}, "gene_names": [ { "name": "Dapk2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07", "id": "A0A0G2JX07" } ], "protein_names": [ { "name": "Death-associated protein kinase 2", "resource": "UniProtKB", "type": "synonym", "url": "", "id": "A0A0G2JX07" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "common_name": "Rat" } ], "gene": [ { "name": "Dapk2", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07", "locus": { "chromosome": "8", "start_pos": 66825567, "end_pos": 66706609, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000017332", "url": "https://www.ensembl.org/id/ENSRNOG00000017332" } ] } } ], "crossref": [ { "id": "ENSRNOG00000017332", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000017332", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14196", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14196", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ERTVAMF", "url": "https://omabrowser.org/oma/group/ERTVAMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24342:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24342:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "http://pfam.xfam.org/family/PF00069", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "1304708", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1304708", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0G2JX07-1", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GD46", "url": "https://www.uniprot.org/uniprot/A0A8I6GD46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8I6GD46-1", "url": "https://www.uniprot.org/uniprot/A0A8I6GD46-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "VVQASMRSPNMETFKQQKVEDFYDIGEELGSGQFAIVRKCREQSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWIMPVDNQQAMVRRESVVNLENFKKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRTSEDLRNCESDTEENIARRKALHPRRRSSTS", "length": 370, "header": "tr|A0A0G2JX07-1|A0A0G2JX07_RAT Isoform 1 of Death-associated protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Dapk2 PE=1 SV=2 CANONICAL=A0A0G2JX07-1" }, "isoforms": [ { "isoform_ac": "A0A0G2JX07-1", "url": "", "sequence": { "sequence": "VVQASMRSPNMETFKQQKVEDFYDIGEELGSGQFAIVRKCREQSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWIMPVDNQQAMVRRESVVNLENFKKQYVRRRWKLSFSIVSLCNHLTRSLMKKVHLRTSEDLRNCESDTEENIARRKALHPRRRSSTS", "length": 370, "header": "tr|A0A0G2JX07-1|A0A0G2JX07_RAT Isoform 1 of Death-associated protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Dapk2 PE=1 SV=2 CANONICAL=A0A0G2JX07-1" }, "locus": { "chromosome": "8", "start_pos": 66825032, "end_pos": 66713828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000089147.2", "url": "https://www.ensembl.org/id/ENSRNOT00000089147.2" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000070087.2", "url": "https://www.ensembl.org/id/ENSRNOP00000070087.2" } ] } }, { "isoform_ac": "A0A8I6GD46-1", "url": "", "sequence": { "sequence": "VVQASMRSPNMETFKQQKVEDFYDIGEELGSGQFAIVRKCREQSTGLEYAAKFIKKRQSRASRRGVCREEIEREVSILRQVLHPNIITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGVNYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPEIVNYEPLGLEADMWSIGVITYILLSGASPFLGDTKQETLANITAVSYDFDEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWIMSKGEASVPEQWKTQPAQLKTKRLREYTLKCHSSMPPNNTYVNFERFAHVVEDVARVDEGCHALAGAHDTLQDDVESLVSIYNEKEAWYREENENARHNLSQLKYEFRKVESLKKLLREDIQAAGASLGGVARKLDHLQVQFETLRQQLSADIQWMQEMAGILQLESGNTDGHALGSVFHRDTSESLPELLNRSHTEGILAGLNL", "length": 490, "header": "tr|A0A8I6GD46-1|A0A0G2JX07_RAT Computationally mapped isoform of Death-associated protein kinase 2 OS=Rattus norvegicus OX=10116 GN=Dapk2 PE=1 SV=1 CANONICAL=A0A0G2JX07-1" }, "locus": { "chromosome": "8", "start_pos": 66811006, "end_pos": 66713828, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000098258.1", "url": "https://www.ensembl.org/id/ENSRNOT00000098258.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000085631.1", "url": "https://www.ensembl.org/id/ENSRNOP00000085631.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" }, { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "protein phosphorylation", "id": "GO:0006468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006468", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": "https://www.uniprot.org/uniprot/A0A0G2JX07" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A0G2JX07", "url": 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