{ "uniprot_canonical_ac": "A6JAS9-1", "uniprot_ac": "A6JAS9", "uniprot_id": "A6JAS9_RAT", "mass": { "chemical_mass": 72795.0, "monoisotopic_mass": 72795.0 }, "refseq": { "ac": "NP_001099728", "name": "TBC1 domain family member 17", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099728" }, "gene_names": [ { "name": "Tbc1d17", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A6JAS9", "id": "A6JAS9" }, { "name": "Tbc1d17", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099728", "id": "NP_001099728" } ], "protein_names": [ { "name": "TBC1 domain family member 17", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099728", "id": "NP_001099728" }, { "name": "TBC1 domain family, member 17", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A6JAS9/entry#names_and_taxonomy", "id": "A6JAS9" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A6JAS9", "url": "https://www.uniprot.org/uniprot/A6JAS9" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Tbc1d17", "url": "https://www.uniprot.org/uniprot/A6JAS9", "locus": { "chromosome": "1", "start_pos": 95322737, "end_pos": 95333005, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000020191", "url": "https://www.ensembl.org/id/ENSRNOG00000020191" } ] } } ], "crossref": [ { "id": "ENSRNOG00000020191", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000020191", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "292886", "url": "https://www.ncbi.nlm.nih.gov/gene/292886", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021935", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021935", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:292886", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:292886", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CFAILME", "url": "https://omabrowser.org/oma/group/CFAILME/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "164430at2759", "url": "http://www.orthodb.org/?query=164430at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22957:SF360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22957:SF360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "http://pfam.xfam.org/family/PF00566", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF12068", "url": "http://pfam.xfam.org/family/PF12068", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001099728", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099728", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1309686", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1309686", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A6JAS9", "url": "https://www.uniprot.org/uniprot/A6JAS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A6JAS9-1", "url": "https://www.uniprot.org/uniprot/A6JAS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F7F3L4", "url": "https://www.uniprot.org/uniprot/F7F3L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F7F3L4-1", "url": "https://www.uniprot.org/uniprot/F7F3L4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEGSSYRVVFEKGGVYLHTSARKHQDPDSLIAGVLRVVEKDNDVLLHWAPVEEAGDPTQIFFSKKDPSGGEPSTSEEEPTFDPGYEPDWAVISTVRPRPHLAEPRRGAEPSSPRSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASSPDLPPLPDDEPEPGFEVISCVELGQRPTVERAPPVTEEEWNRHVGPEGRLQNVPELKSRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEILGLAQPEEPSSPSPPVSPMPLSPTRAPMPPPPPEEVAPQPDSSLEILPEDEDGA", "length": 646, "header": "tr|A6JAS9-1|A6JAS9_RAT Isoform 1 of TBC1 domain family, member 17 OS=Rattus norvegicus OX=10116 GN=Tbc1d17 PE=1 SV=1 CANONICAL=A6JAS9-1" }, "isoforms": [ { "isoform_ac": "A6JAS9-1", "url": "https://www.uniprot.org/uniprotkb/A6JAS9/entry#A6JAS9-1", "sequence": { "sequence": "MEGSSYRVVFEKGGVYLHTSARKHQDPDSLIAGVLRVVEKDNDVLLHWAPVEEAGDPTQIFFSKKDPSGGEPSTSEEEPTFDPGYEPDWAVISTVRPRPHLAEPRRGAEPSSPRSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASSPDLPPLPDDEPEPGFEVISCVELGQRPTVERAPPVTEEEWNRHVGPEGRLQNVPELKSRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEILGLAQPEEPSSPSPPVSPMPLSPTRAPMPPPPPEEVAPQPDSSLEILPEDEDGA", "length": 646, "header": "tr|A6JAS9-1|A6JAS9_RAT Isoform 1 of TBC1 domain family, member 17 OS=Rattus norvegicus OX=10116 GN=Tbc1d17 PE=1 SV=1 CANONICAL=A6JAS9-1" }, "locus": { "chromosome": "1", "start_pos": 95332979, "end_pos": 95324975, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000102187.1", "url": "https://www.ensembl.org/id/ENSRNOT00000102187.1" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000097505.1", "url": "https://www.ensembl.org/id/ENSRNOP00000097505.1" } ] } }, { "isoform_ac": "F7F3L4-1", "url": "https://www.uniprot.org/uniprotkb/A6JAS9/entry#F7F3L4-1", "sequence": { "sequence": "MEGSSYRVVFEKGGVYLHTSARKHQDPDSLIAGVLRVVEKDNDVLLHWAPVEEAGDPTQIFFSKKDPSGGEPSTSEEEPTFDPGYEPDWAVISTVRPRPHLAEPRRGAEPSSPRSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASSPDLPPLPDDEPEPGFEVISCVELGQRPTVERAPPVTEEEWNRHVGPEGRLQNVPELKSRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEILGLAQPEEPSSPSPPWPRSLTAVWRFCLRMKMVLDC", "length": 626, "header": "tr|F7F3L4-1|A6JAS9_RAT Computationally mapped isoform of TBC1 domain family, member 17 OS=Rattus norvegicus OX=10116 GN=Tbc1d17 PE=1 SV=1 CANONICAL=A6JAS9-1" }, "locus": { "chromosome": "1", "start_pos": 95332979, "end_pos": 95324968, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000027436.7", "url": "https://www.ensembl.org/id/ENSRNOT00000027436.7" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000027436.6", "url": "https://www.ensembl.org/id/ENSRNOP00000027436.6" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "F7F3L4", "url": "https://www.uniprot.org/uniprot/F7F3L4" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] } ], "pathway": [ { "id": "rno:292886", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:292886", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RHU3-1", "protein_name": "TBC1 domain family member 17 isoform X2", "gene_name": "TBC1D17", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGAGYRVVFEKGGVYLHTSAKKHQDPDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQIFFSKKDPSGGDSCPSEEEPTFDPGYEPDWAVISTVRPRPRHSEPTRGAEPSSPRGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASPDLPPAPDDEPEPGFEVISCVELGPRPAVERAPPVTEEEWARHVGPEGRLQQVPELKARIFSGGLSPSLRREAWKFLLGYLSWEGSAEEHKAHVRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVTQNEVDAFWCFCGFMELVHRNFEESQETMKRQLGQLLLLLRVLDPPLCDFLDAQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACRELPHNVQEVLGLAPPAEPQSPSPPASPLPLSPARAPPAPPPPADTVQQPDSSLEILPEEEEEESADS", "length": 649 }, "evidence": [ { "id": "A6JAS9", "url": "https://omabrowser.org/oma/group/A6JAS9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BYH7-1", "protein_name": "TBC1 domain family member 17", "gene_name": "Tbc1d17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGSSYRVVFEKGGVYLHTSARKHQDPDSLIAGVIRVVEKDSDVFLHWAPVEEAGDPTQILFKKDPSRGEPSTSEEEPTFDPGYEPDWAVISTVRPQPHLAEPRKGAEPSSSRSSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPQDPSALSDSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPHPEGASSPNLPPLPDDEPEPGFEVISCVELGQRPTVERAPPVTEEEWNRYVGPEGRLQNVPELKNRIFSGGLSPGLRREAWKFLLGYLSWESSAEEHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLSLLHDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKRQLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEILGLAQPEEPSSPSPPVSPMPLSPTRAPLPPPLPEEVIPQPDSSLEILPEDEDGA", "length": 645 }, "evidence": [ { "id": "46366294", "url": "http://www.informatics.jax.org/homology/46366294", "database": "MGI" }, { "id": "A6JAS9", "url": "https://omabrowser.org/oma/group/A6JAS9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HA65-1", "protein_name": "TBC1 domain family member 17", "gene_name": "TBC1D17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGAGYRVVFEKGGVYLHTSAKKYQDRDSLIAGVIRVVEKDNDVLLHWAPVEEAGDSTQILFSKKDSSGGDSCASEEEPTFDPGYEPDWAVISTVRPQLCHSEPTRGAEPSCPQGSWAFSVSLGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLLASSPQDSRLYLVFPHDSSALSNSFHHLQLFDQDSSNVVSRFLQDPYSTTFSSFSRVTNFFRGALQPQPEGAASDLPPPPDDEPEPGFEVISCVELGPRPTVERGPPVTEEEWARHVGPEGRLQQVPELKNRIFSGGLSPSLRREAWKFLLGYLSWEGTAEEHKAHIRKKTDEYFRMKLQWKSVSPEQERRNSLLHGYRSLIERDVSRTDRTNKFYEGPENPGLGLLNDILLTYCMYHFDLGYVQGMSDLLSPILYVIQNEVDAFWCFCGFMELVQGNFEESQETMKRQLGRLLLLLRVLDPLLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLHLLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALHRQLTACPELPHNVQEILGLAPPAEPHSPSPTASPLPLSPTRAPPTPPPSTDTAPQPDSSLEILPEEEDEGADS", "length": 648 }, "evidence": [ { "id": "46366294", "url": "http://www.informatics.jax.org/homology/46366294", "database": "MGI" }, { "id": "A6JAS9", "url": "https://omabrowser.org/oma/group/A6JAS9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A6JAS9", "url": "https://www.uniprot.org/uniprot/A6JAS9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A6JAS9", "url": "https://www.uniprot.org/uniprot/A6JAS9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": "A6JAS9", "url": "https://www.uniprot.org/uniprot/A6JAS9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }