{ "uniprot_canonical_ac": "A6HS75-1", "uniprot_ac": "A6HS75", "uniprot_id": "A6HS75_RAT", "mass": { "chemical_mass": 50172.0, "monoisotopic_mass": 50172.0 }, "refseq": { "ac": "NP_001108498", "name": "speriolin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108498" }, "gene_names": [ { "name": "Spatc1", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A6HS75", "id": "A6HS75" }, { "name": "RGD1565316", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108498", "id": "NP_001108498" }, { "name": "RGD1565316", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A6HS75", "id": "A6HS75" }, { "name": "Spatc1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108498", "id": "NP_001108498" } ], "protein_names": [ { "name": "RGD1565316 protein", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A6HS75/entry#names_and_taxonomy", "id": "A6HS75" }, { "name": "Spermatogenesis and centriole associated 1", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A6HS75/entry#names_and_taxonomy", "id": "A6HS75" }, { "name": "speriolin", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108498", "id": "NP_001108498" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Rattus norvegicus", "taxid": 10116, "evidence": [ { "database": "UniProtKB", "id": "A6HS75", "url": "https://www.uniprot.org/uniprot/A6HS75" } ], "common_name": "Rat", "glygen_name": "Rat", "reference_species": "Rattus norvegicus [10116]" } ], "gene": [ { "name": "Spatc1", "url": "https://www.uniprot.org/uniprot/A6HS75", "locus": { "chromosome": "7", "start_pos": 108007479, "end_pos": 107983796, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSRNOG00000029590", "url": "https://www.ensembl.org/id/ENSRNOG00000029590" } ] } } ], "crossref": [ { "id": "ENSRNOG00000029590", "url": "https://bgee.org/?page=gene&gene_id=ENSRNOG00000029590", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "315091", "url": "https://www.ncbi.nlm.nih.gov/gene/315091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "rno:315091", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:315091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NDHKLDE", "url": "https://omabrowser.org/oma/group/NDHKLDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "5347025at2759", "url": "http://www.orthodb.org/?query=5347025at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22192:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22192:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15058", "url": "http://pfam.xfam.org/family/PF15058", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF15059", "url": "http://pfam.xfam.org/family/PF15059", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "NP_001108498", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108498", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "1565316", "url": "http://rgd.mcw.edu/tools/genes/genes_view.cgi?id=1565316", "database": "RGD", "categories": [ "Organism-specific" ] }, { "id": "A6HS75", "url": "https://www.uniprot.org/uniprot/A6HS75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A6HS75-1", "url": "https://www.uniprot.org/uniprot/A6HS75-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLLTNYEGLRHQIERLVRENEELKKLVRLIRENHELKSAIKTQAGGLGIGGLCEAAAGPSQQGVFLSPSPAAAKDPRAEDMGMVTLAPLADMLNTPQLNPAAGSLVNPLAAPLNPLLSGQLPLSQNNQFANFVPCPISNQLTSPIALPPGVTLASSLGLPSTGPLNSQMTSPMAVPPGTTLASSLGLNSTGSLTTNSRLVGPPAVSQSGPIMAPLAGTVAVSLSSPLVSSTAPLGVSQNILPNPINNVGLSEAPRVRLTEPTRGNLSGTSAGPAPASKVNDARGSRVAEQSRKNAPETERKATSRKSNKLPDSCRDSKQLARERLVGEIAFQLDRRILSSIFPERVRLYGFTVSNIPEKIIQASLNPSSHKLDEDLCQTLTQRYVSIMNRLQSLGYNGRVHPALTEQLVNAYGILRERPELAASEGGTYSVDFLQRVLVETVHPSMLTDALLLLSCLNQLSHDDGKPMFIW", "length": 472, "header": "tr|A6HS75-1|A6HS75_RAT Isoform 1 of Spermatogenesis and centriole associated 1 OS=Rattus norvegicus OX=10116 GN=Spatc1 PE=1 SV=1 CANONICAL=A6HS75-1" }, "isoforms": [ { "isoform_ac": "A6HS75-1", "url": "https://www.uniprot.org/uniprotkb/A6HS75/entry#A6HS75-1", "sequence": { "sequence": "MSLLTNYEGLRHQIERLVRENEELKKLVRLIRENHELKSAIKTQAGGLGIGGLCEAAAGPSQQGVFLSPSPAAAKDPRAEDMGMVTLAPLADMLNTPQLNPAAGSLVNPLAAPLNPLLSGQLPLSQNNQFANFVPCPISNQLTSPIALPPGVTLASSLGLPSTGPLNSQMTSPMAVPPGTTLASSLGLNSTGSLTTNSRLVGPPAVSQSGPIMAPLAGTVAVSLSSPLVSSTAPLGVSQNILPNPINNVGLSEAPRVRLTEPTRGNLSGTSAGPAPASKVNDARGSRVAEQSRKNAPETERKATSRKSNKLPDSCRDSKQLARERLVGEIAFQLDRRILSSIFPERVRLYGFTVSNIPEKIIQASLNPSSHKLDEDLCQTLTQRYVSIMNRLQSLGYNGRVHPALTEQLVNAYGILRERPELAASEGGTYSVDFLQRVLVETVHPSMLTDALLLLSCLNQLSHDDGKPMFIW", "length": 472, "header": "tr|A6HS75-1|A6HS75_RAT Isoform 1 of Spermatogenesis and centriole associated 1 OS=Rattus norvegicus OX=10116 GN=Spatc1 PE=1 SV=1 CANONICAL=A6HS75-1" }, "locus": { "chromosome": "7", "start_pos": 108007397, "end_pos": 107983880, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSRNOT00000050522.4", "url": "https://www.ensembl.org/id/ENSRNOT00000050522.4" }, { "database": "Ensembl Peptide", "id": "ENSRNOP00000041285.3", "url": "https://www.ensembl.org/id/ENSRNOP00000041285.3" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues.", "journal": "Nat. Commun.", "date": "2012", "authors": "Lundby A, Secher A, Lage K, Nordsborg NB, Dmytriyev A, Lundby C, Olsen JV", "evidence": [ { "database": "UniProtKB", "id": "A6HS75", "url": "https://www.uniprot.org/uniprot/A6HS75" } ], "reference": [ { "type": "PubMed", "id": "22673903", "url": "https://glygen.org/publication/PubMed/22673903" } ] } ], "pathway": [ { "id": "rno:315091", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+rno:315091", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q148B6-1", "protein_name": "Speriolin", "gene_name": "Spatc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLLTSYEGLRHQIERLVRENEELKKLVRLIRENQELKSAIKTQAGGLCISGFTGGLGEAAAGPPQHQGVFLPPASAAAKEPCSEDLGMVALAPLADMLNTPQLSPAAGSLVNPLAATLNPLLSGQIPLLQNNQFANLVPCSMSNQLTNPTTVSPGVTLASSLGLPSTGPLNSQMTSPMTVPPGTTLASSLGLTSTGSLTTSSRLVGPLAVSQSSPIMAPLAGTVAVSLSSPLLSSTATPLGVAQNVVPNPINNIGQPETPRVRRAEPTRGNFSGTSAYAGPAPTSKVNDTRGSRVMEQSRKNVVEMERKTPHRKSNKLPDNPRDTKQLVCERLVGEIAFQLDRRILSSIFPERVRLYGFTVSNIPEKIIQASLNPSNHKLDEDLCQTLTQRYVSIMNKLQSLGYNGRVHPALTEQLVNEYGILRERPELAASEGGCYTVDFLQRVLLETVHPSKLTDALLLLSCLHQLSHDDGKPMFIW", "length": 480 }, "evidence": [ { "id": "46377385", "url": "http://www.informatics.jax.org/homology/46377385", "database": "MGI" }, { "id": "A6HS75", "url": "https://omabrowser.org/oma/group/A6HS75/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76KD6-1", "protein_name": "Speriolin", "gene_name": "SPATC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLLTNYEGLRHQIERLVRENEELKKLVRLIRENHELKSAIKTQAGGLGISGFTSGLGEATAGLSSRQNNGVFLPPSPAVANERVLEEVGIMALAPLAEMLTSLQPSATPGSLMSPLTGTLSTLLSGPAPTSQSSPLTSFLTSPIAGPLTGTLASSLGLPSTGTLTPSSLVAGPVAMSQSSPLIAPVMGTVAVSLSSPLLSSTATPPGVSQNLLANPMSNLVLPEAPRLRLAEPLRGGPTGPQSPACVVPTATTKVPLSTEPPQSTQDPEPLSMAFAGAPLQTSTPIGAMGTPAPKTAFSFNTSDTQAQPSAAQEQVVPASVPTSPTTSPTVTVLASAPALAPQVATSYTPSSTTHIAQGAPHPPSRMHNSPTQNLPVPHCPPHNAHSPPRTSSSPASVNDSRGPRTTEPSTKSMMEVERKLAHRKTSKFPENPRESKQLAWERLVGEIAFQLDRRILSSIFPERVRLYGFTVSNIPEKIIQASLNPSDHKLDEKLCQRLTQRYVSVMNRLQSLGYNGRVHPALTEQLVNAYGILRERPELAASEGGPYTVDFLQRVVVETVHPGMLADALLLLSCLSQLAHDDGKPMFIW", "length": 591 }, "evidence": [ { "id": "46377385", "url": "http://www.informatics.jax.org/homology/46377385", "database": "MGI" }, { "id": "A6HS75", "url": "https://omabrowser.org/oma/group/A6HS75/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A6HS75", "url": "https://www.uniprot.org/uniprot/A6HS75" } ], "pmid": "" }, { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A6HS75", "url": "https://www.uniprot.org/uniprot/A6HS75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gamma-tubulin binding", "id": "GO:0043015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043015", "evidence": [ { "database": "UniProtKB", "id": "A6HS75", "url": "https://www.uniprot.org/uniprot/A6HS75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.mgi", "label": "MGI Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 266, "end_pos": 268 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }