{
    "uniprot_canonical_ac": "A2AU72-1",
    "uniprot_ac": "A2AU72",
    "uniprot_id": "ARMC3_MOUSE",
    "mass": {
        "chemical_mass": 97357.0,
        "monoisotopic_mass": 97357.0
    },
    "refseq": {
        "ac": "NP_001074552",
        "name": "armadillo repeat-containing protein 3 isoform 1",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552"
    },
    "gene_names": [
        {
            "name": "Armc3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A2AU72",
            "id": "A2AU72"
        },
        {
            "name": "4921513G22Rik",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552",
            "id": "NP_001074552"
        },
        {
            "name": "Armc3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552",
            "id": "NP_001074552"
        }
    ],
    "protein_names": [
        {
            "name": "Armadillo repeat-containing protein 3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A2AU72/entry#names_and_taxonomy",
            "id": "A2AU72"
        },
        {
            "name": "armadillo repeat-containing protein 3 isoform 1",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552",
            "id": "NP_001074552"
        },
        {
            "name": "armadillo repeat-containing protein 3",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552",
            "id": "NP_001074552"
        }
    ],
    "function": [
        {
            "annotation": "Armc3 is most abundantly expressed in tissues rich in highly ciliated cells, such as olfactory sensory neurons, and is predicted to be important to cilia.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001074552",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552"
                },
                {
                    "database": "PubMed",
                    "id": "17971504",
                    "url": "https://glygen.org/publication/PubMed/17971504"
                }
            ]
        },
        {
            "annotation": "Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001074552",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552"
                },
                {
                    "database": "PubMed",
                    "id": "34428398",
                    "url": "https://glygen.org/publication/PubMed/34428398"
                }
            ]
        },
        {
            "annotation": "Essential for male fertility and sperm motility. During spermatogenesis, promotes the autophagic degradation of excessive ribosomes, providing energy resources for mitochondria and thus ensuring sperm flagellar motility.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AU72",
                    "url": "https://www.uniprot.org/uniprot/A2AU72#function"
                },
                {
                    "database": "PubMed",
                    "id": "34428398",
                    "url": "https://glygen.org/publication/PubMed/34428398"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [
        {
            "start_pos": 507,
            "end_pos": 507,
            "sequence_org": "C",
            "sequence_mut": "A",
            "comment": "Reduced level of palmitoylation and inability to rescue the autophagic flux in ARMC3-deficient embryonic fibrobalsts; when associated with A-518.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AU72",
                    "url": "https://www.uniprot.org/uniprot/A2AU72"
                },
                {
                    "database": "PubMed",
                    "id": "34428398",
                    "url": "https://glygen.org/publication/PubMed/34428398"
                }
            ]
        },
        {
            "start_pos": 518,
            "end_pos": 518,
            "sequence_org": "C",
            "sequence_mut": "A",
            "comment": "Reduced level of palmitoylation and inability to rescue the autophagic flux in ARMC3-deficient embryonic fibrobalsts; when associated with A-507.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AU72",
                    "url": "https://www.uniprot.org/uniprot/A2AU72"
                },
                {
                    "database": "PubMed",
                    "id": "34428398",
                    "url": "https://glygen.org/publication/PubMed/34428398"
                }
            ]
        }
    ],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Mus musculus",
            "taxid": 10090,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AU72",
                    "url": "https://www.uniprot.org/uniprot/A2AU72"
                }
            ],
            "common_name": "Mouse",
            "glygen_name": "Mouse",
            "reference_species": "Mus musculus [10090]"
        }
    ],
    "gene": [
        {
            "name": "Armc3",
            "url": "https://www.uniprot.org/uniprot/A2AU72",
            "locus": {
                "chromosome": "2",
                "start_pos": 19315052,
                "end_pos": 19204113,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSMUSG00000037683",
                        "url": "https://www.ensembl.org/id/ENSMUSG00000037683"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSMUSG00000037683",
            "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000037683",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "70882",
            "url": "https://www.ncbi.nlm.nih.gov/gene/70882",
            "database": "GeneID",
            "categories": [
                "Genome Annotation"
            ]
        },
        {
            "id": "IPR000225",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR011989",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR016024",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "mmu:70882",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:70882",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "1918132",
            "url": "http://www.informatics.jax.org/marker/MGI:1918132",
            "database": "MGI",
            "categories": [
                "Organism-specific"
            ]
        },
        {
            "id": "LYPMQSR",
            "url": "https://omabrowser.org/oma/group/LYPMQSR/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "3152378at2759",
            "url": "http://www.orthodb.org/?query=3152378at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR46618",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46618",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR46618:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46618:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00514",
            "url": "http://pfam.xfam.org/family/PF00514",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF14381",
            "url": "http://pfam.xfam.org/family/PF14381",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PR_A2AU72",
            "url": "http://purl.obolibrary.org/obo/PR_A2AU72",
            "database": "PRO",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "NP_001074552",
            "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AU71",
            "url": "https://www.uniprot.org/uniprot/A2AU71",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AU71-1",
            "url": "https://www.uniprot.org/uniprot/A2AU71-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AU72",
            "url": "https://www.uniprot.org/uniprot/A2AU72",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AU72-1",
            "url": "https://www.uniprot.org/uniprot/A2AU72-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A2AU72-2",
            "url": "https://www.uniprot.org/uniprot/A2AU72-2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MGKKIKKEVEPPPKDVFDPITIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKTVRRNAMMIFGILASNSDVKKLLRELEVMNSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSSDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVITCDKEARTMLKENQGLDHLTKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSLKKVLSFAESSTIPDIQKNAAKAIAKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISALCENLSCKEFFNTQGIPQIVQLLRSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAIANAATVLTNMATQEPLRAIIQNHEIMHALLGPLHSTNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHSKNDEVRRHASWAVMVCAGDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLSLKELCLQELNDQRAILLVNNKSDTSPPPSMEDKSSDVGYGRSISSSSSLRRGSKEKANAIFGSPTEEKSEPASVRNTILSRAFTKEKGVSKKKSRLQLICSSYLLWKGKGKKEEEKVKEEEEILALPKFTEGSPEKEWNPPPDPEFCVYVLEVTKSILPIVNLKEQIEVLAKYVADKMGGKIPKEKLADFSWELHISELKFQLKSNVVPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGMIGNLPPPEEYIVDLMFHPGNLLKLRSKEADLYRFL",
        "length": 881,
        "header": "sp|A2AU72-1|ARMC3_MOUSE Isoform 1 of Armadillo repeat-containing protein 3  OS=Mus musculus OX=10090 GN=Armc3 PE=1 SV=1 CANONICAL=A2AU72-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A2AU71-1",
            "url": "https://www.uniprot.org/uniprotkb/A2AU72/entry#A2AU71-1",
            "sequence": {
                "sequence": "MGKKIKKEVEPPPKDVFDPITIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKTVRRNAMMIFGILASNSDVKKLLRELEVMNSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSSDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVITCDKEARTMLKENQGLDHLTKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSLKKVLSFAESSTIPDIQKNAAKAIAKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISALCENLSCKEFFNTQGIPQIVQLLRSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAIANAATVLTNMATQEPLRAIIQNHEIMHALLGPLHSTNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHSKNDEVRRHASWAVMVCAGDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLSLKELCLQELNDQRAILLVNNKSDTSPPPSMEDKSSDVGYGRSISSSSSLRRGSKEKANFRFSAIFGSPTEEKSEPASVRNTILSRAFTKEKGVRKGKGKKEEEKVKEEEEILALPKFTEGSPEKEWNPPPDPEFCVYVLEVTKSILPIVNLKEQIEVLAKYVADKMGGKIPKEKLADFSWELHISELKFQLKSNVVPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGMIGNLPPPEEYIVDLMFHPGNLLKLRSKEADLYRFL",
                "length": 869,
                "header": "tr|A2AU71-1|ARMC3_MOUSE Computationally mapped isoform of Armadillo repeat-containing protein 3  OS=Mus musculus OX=10090 GN=Armc3 PE=1 SV=1 CANONICAL=A2AU72-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 19314934,
                "end_pos": 19206579,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000049255.7",
                        "url": "https://www.ensembl.org/id/ENSMUST00000049255.7"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000048784.7",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000048784.7"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AU72-1",
            "url": "https://www.uniprot.org/uniprotkb/A2AU72/entry#A2AU72-1",
            "sequence": {
                "sequence": "MGKKIKKEVEPPPKDVFDPITIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKTVRRNAMMIFGILASNSDVKKLLRELEVMNSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSSDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVITCDKEARTMLKENQGLDHLTKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSLKKVLSFAESSTIPDIQKNAAKAIAKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISALCENLSCKEFFNTQGIPQIVQLLRSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAIANAATVLTNMATQEPLRAIIQNHEIMHALLGPLHSTNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHSKNDEVRRHASWAVMVCAGDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLSLKELCLQELNDQRAILLVNNKSDTSPPPSMEDKSSDVGYGRSISSSSSLRRGSKEKANAIFGSPTEEKSEPASVRNTILSRAFTKEKGVSKKKSRLQLICSSYLLWKGKGKKEEEKVKEEEEILALPKFTEGSPEKEWNPPPDPEFCVYVLEVTKSILPIVNLKEQIEVLAKYVADKMGGKIPKEKLADFSWELHISELKFQLKSNVVPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGMIGNLPPPEEYIVDLMFHPGNLLKLRSKEADLYRFL",
                "length": 881,
                "header": "sp|A2AU72-1|ARMC3_MOUSE Isoform 1 of Armadillo repeat-containing protein 3  OS=Mus musculus OX=10090 GN=Armc3 PE=1 SV=1 CANONICAL=A2AU72-1"
            },
            "locus": {
                "chromosome": "2",
                "start_pos": 19314934,
                "end_pos": 19206579,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSMUST00000114640.9",
                        "url": "https://www.ensembl.org/id/ENSMUST00000114640.9"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSMUSP00000110287.3",
                        "url": "https://www.ensembl.org/id/ENSMUSP00000110287.3"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A2AU72-2",
            "url": "https://www.uniprot.org/uniprotkb/A2AU72/entry#A2AU72-2",
            "sequence": {
                "sequence": "MGKKIKKEVEPPPKDVFDPITIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKTVRRNAMMIFGILASNSDVKKLLRELEVMNSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSSDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVITCDKEARTMLKENQGLDHLTKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSLKKVLSFAESSTIPDIQKNAAKAIAKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISALCENLSCKEFFNTQGIPQIVQLLRSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAIANAATVLTNMATQEPLRAIIQNHEIMHALLGPLHSTNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHSKNDEVRRHASWAVMVCAGDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLSLKELCLQELNDQRAILLVNNKSDTSPPPSMEDKSSDVGYGRSISSSSSLRRGSKEKANFRFSAIFGSPTEEKSEPASVRNTILSRAFTKEKGVRKGKG",
                "length": 684,
                "header": "sp|A2AU72-2|ARMC3_MOUSE Isoform 2 of Armadillo repeat-containing protein 3  OS=Mus musculus OX=10090 GN=Armc3 PE=1 SV=1 CANONICAL=A2AU72-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Tissue expression patterns identify mouse cilia genes.",
            "journal": "Physiological genomics",
            "date": "2008",
            "authors": "McClintock TS, Glasser CE, Bose SC, Bergman DA",
            "evidence": [
                {
                    "database": "RefSeq",
                    "id": "NP_001074552",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "17971504",
                    "url": "https://glygen.org/publication/PubMed/17971504"
                }
            ]
        },
        {
            "title": "Autophagic elimination of ribosomes during spermiogenesis provides energy for flagellar motility.",
            "journal": "Developmental cell",
            "date": "2021",
            "authors": "Lei Y, Zhang X, Xu Q, Liu S, Li C, Jiang H, Lin H, Kong E, Liu J, Qi S, Li H, Xu W, Lu K",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AU72",
                    "url": "https://www.uniprot.org/uniprot/A2AU72"
                },
                {
                    "database": "RefSeq",
                    "id": "NP_001074552",
                    "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074552"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "34428398",
                    "url": "https://glygen.org/publication/PubMed/34428398"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "mmu:70882",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:70882",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A8V0XNH0-1",
            "protein_name": "Armadillo repeat containing 3",
            "gene_name": "ARMC3",
            "tax_id": 9031,
            "organism": "Gallus gallus",
            "sequence": {
                "sequence": "MGKKVKKEVEPPPKDVFEPLLIESKAAATVVLMLDSPEEEVLAKACDAIYKFASKGDENKVALLGLGAVERLYKLISHEDPIVRRNAIMVFGIMASNHDVKKLLRELDVTSSLLSHLVPEEDVIIHEFATLCLAHMAVEYTTKVQIFEQGGLEPLISLLGSPDPDVTKNSVECIYLLVQEFQSRAAVCELNVIPPLLDLLKSEYPVIQLLALKTLEVISKDREMRIILGENEGLDCLLKILETNEFNDLHVEALAVLGNCLEDVHTMQLIRQTGGLKKLLSFVGVSTVPDIQKNAAKAIAKAASDSENRKILNEEGVENCLINLLEIDDDGVKVAASQAISAMCENLASKRAFGLQGIPQLVQLLSSDDEEVKEAAVIALANLTTASPSNASAVAEAEGIEPLVKSLNAERHGAVANAATVLTNMAMQEPLRLSIQSHGVMSVLTEPLRSSSSQVQSRAALTVAAFGCDANARSELRNAGGLGPLVELLHSKDKEVRRNACWAVMVCASDELTAVELCRLGALDILEEINLSTGRRNNFSEAALERLLDNNLSQKYSQMGYLSSSNVITDGFYDYGKIKPGVKLLSLEELSMQELTDRRAIIFINAKPQEDVLAMEEKPQHISSEQTTLSVPTSRKSSREKVRKGKGKKEEEKIKEVVEIMSEVQDEINLEDVQWQPPPDFMLMNYINDASKIILPLTTTREQVVALAQFVADKMGGAIERDKLHDFSWELHISEIEFELKSNIVPIGKVKKGTFYHRALLFKVIADRLGIGCSLVRGEYNRAWNEVKLVDDSPQGVTGLLLPPQEYIVDLMFVPGFLMKQESVEADQYKHI",
                "length": 832
            },
            "evidence": [
                {
                    "id": "A2AU72",
                    "url": "https://omabrowser.org/oma/group/A2AU72/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Chicken",
            "common_name": "Chicken"
        },
        {
            "uniprot_canonical_ac": "M0R914-1",
            "protein_name": "Armadillo repeat containing 3",
            "gene_name": "Armc3",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MAPAGLIVLELDKGSLGTKNQFGAEHAGAAQRRLATSINTDPQRPVQFVTCKEPLLRDLTPRRMGKKIKKEVEPPPKDVFDPLTIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKIVRRNAMMIFGILASNSDVKKLLRELEVMSSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSPDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLKSEYPIIQLLALKTLGVITCDKEARTTLKDNQGLDHLTKILETKELNDLHVEALAVIANCLEDMDTMVLMQQSGSLKKVLSFAENSTIPDIQKNAAKAITKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISAMCENLSCKEFFNTQGIPQIVQLLKSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAVANAATVLTNMAIQEPLRAIIQNHEIMRALLGPLHSTNTVVQSTAALTVAATACDVESRNELKNCGGLEPLIELLHSKNDEVRRHASWAIMVCAGDELMAVELCRLGALDILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLPLKELCLQELNDQRAILLVNNKSDISPPPSMEDKSSDVGYGRSISSSSSLRRASKEKANAGFGSPTEEKSEPASGRNTVLSRGATKEKGARKGKGKKEEEKVKEEEEVLAVPKLTESPEKEWYPPPDPEFCLYVLEVIKTILPIVNIKEQIEVLAKFVADKMGGKIAKEKLADFSWELHISELKFQLKSNVIPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGIIGNLPPPDEYIVDLMFHPGTLLKLRSKEADLYRFL",
                "length": 927
            },
            "evidence": [
                {
                    "id": "A2AU72",
                    "url": "https://omabrowser.org/oma/group/A2AU72/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Rat",
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "Q5W041-2",
            "protein_name": "Armadillo repeat-containing protein 3",
            "gene_name": "ARMC3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MGKKIKKEVEPPPKDVFDPLMIESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAVMVCAGDELTANELCRLGALDILEEVNVSGTRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIINDGFYDYGRINPGTKLLPLKELCLQEPSDLRAVLLINSKSYVSPPSSMEDKSDVGYGRSISSSSSLRRSSKEKNKKNSYHFSAGFGSPIEDKSEPASGRNTVLSKSATKEKGWRKSKGKKEEEKVKEEEEVMVVPKFVGEGSSDKEWCPPSDPDFSMYVYEVTKSILPITNIKEQIEDLAKYVAEKMGGKIPKEKLPDFSWELHISELKFQLKSNVIPIGHVKKGIFYHRALLFKALADRIGIGCSLVRGEYGRAWNEVMLQNDSRKGVIGGLPAPEMYVIDLMFHPGGLMKLRSREADLYRFI",
                "length": 872
            },
            "evidence": [
                {
                    "id": "46370770",
                    "url": "http://www.informatics.jax.org/homology/46370770",
                    "database": "MGI"
                },
                {
                    "id": "A2AU72",
                    "url": "https://omabrowser.org/oma/group/A2AU72/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        },
        {
            "uniprot_canonical_ac": "Q7JYM7-1",
            "protein_name": "GH11924p",
            "gene_name": "Dmel\\CG13326",
            "tax_id": 7227,
            "organism": "Drosophila melanogaster",
            "sequence": {
                "sequence": "MSRISKRVYEAKSTYPDRTKSEEKSFTEVSVPIKKLDTALLLLSSKEECVLLTIFSHITDFARRQDVNVLELKAHRLLELLLEKDLFIASENTMIRRFALYLLTALLDNTDMSTYEPEQADQILELACRFYMKEVDDFCIEYLTYILNVCLKDPQMAHGIVEATEFLEKFKLVFISSENPDTVFNSIEALHRMLLVQSADQMLDFTTQPDFPVDRIICEVTNEFQEIRKAALKTLKTLLADTGDDSVFEALHRCYFVLEQLVKVFCESPQGPEAADVIEVLATALRSEKMTKLFFEQNLFDQVVEQVRNHMDLMPLEMRCTIISIFAETAQYEQFLPRMHKAEIADMFLTCLMQNKPAPAAYVIQGLHRMSHHPEALRRIVAAYQEGAIRKLVAILMSPDVAIKAREQAGEFLSRLLVAAFRETAAQLQEQDIAVVLTAVIAQGQPTLSIDLILLLLTIIESLAQKEEYRTILGEYSSLTEQLAQLLMRSFAHSILVNNIFRCLCTLIDEAPVRETLLANYIVSSMKRALKSLSNLVKTSVTNFILQTTRFNEFIDAYIDRGIMEVLLDFQKHAFCISTWGPAIESILSKCPTMKFAIRNCLTFTDITAGKDFYVSRRKFEDFRKFQDILRNDCSPLDAVLVMNFDRPKPNQNDVIAVPLRCLSTITDLPGDQGWGYCKRPGDNNLPQYLEALNQTLAMHGLVENPERVRRTIDFENVAKRSKLIAQAVNAVMSENLKILDLNSTEECCRNTVRCHLQELRHVLHTNFIPLGMVRSGCQFERAILFKGLADQIGLPCTLQRSVDGRMLYNELPLPLEPEKDVHCDKKTLKYMPWRMLRPTHVVDLLYNVGELYPMQSRQALQYLRLY",
                "length": 867
            },
            "evidence": [
                {
                    "id": "A2AU72",
                    "url": "https://omabrowser.org/oma/group/A2AU72/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Fruit fly",
            "common_name": "Fruit fly"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 3,
                "go_terms": [
                    {
                        "name": "flagellated sperm motility",
                        "id": "GO:0030317",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AU72",
                                "url": "https://www.uniprot.org/uniprot/A2AU72"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "spermatid development",
                        "id": "GO:0007286",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007286",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AU72",
                                "url": "https://www.uniprot.org/uniprot/A2AU72"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "ribophagy",
                        "id": "GO:0034517",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034517",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A2AU72",
                                "url": "https://www.uniprot.org/uniprot/A2AU72"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 135,
            "end_pos": 137,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 346,
            "end_pos": 348,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 382,
            "end_pos": 384,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 530,
            "end_pos": 532,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 551,
            "end_pos": 553,
            "annotation": "n_glycosylation_sequon"
        },
        {
            "start_pos": 606,
            "end_pos": 608,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [
        {
            "annotation": "Palmitoylation is important for its function in autophagy.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A2AU72",
                    "url": "https://www.uniprot.org/uniprot/A2AU72"
                },
                {
                    "database": "PubMed",
                    "id": "34428398",
                    "url": "https://glygen.org/publication/PubMed/34428398"
                }
            ]
        }
    ],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "enzyme_annotation": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        },
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
        },
        {
            "name": "homologset.mgi",
            "label": "MGI Homologs"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 135,
                "end_pos": 137
            },
            {
                "start_pos": 346,
                "end_pos": 348
            },
            {
                "start_pos": 382,
                "end_pos": 384
            },
            {
                "start_pos": 530,
                "end_pos": 532
            },
            {
                "start_pos": 551,
                "end_pos": 553
            },
            {
                "start_pos": 606,
                "end_pos": 608
            }
        ]
    },
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_reported_with_glycan",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_predicted",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "glycosylation_automatic_literature_mining",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                },
                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
                    "count": 0
                },
                {
                    "field": "o_linked_glycans",
                    "count": 0
                },
                {
                    "field": "o_linked_glycan_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "phosphorylation",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "snv_non_disease",
            "table_stats": [
                {
                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
                    "count": 0
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 2
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "date",
                "authors"
            ]
        }
    ]
}