{ "uniprot_canonical_ac": "A2AG50-1", "uniprot_ac": "A2AG50", "uniprot_id": "MA7D2_MOUSE", "mass": { "chemical_mass": 86050.0, "monoisotopic_mass": 86050.0 }, "refseq": { "ac": "NP_001074593", "name": "MAP7 domain-containing protein 2 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593" }, "gene_names": [ { "name": "Map7d2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50" }, { "name": "1600028E09Rik; 2900002G04Rik; 5330432J06Rik; C030036K04Rik; Mtap7d2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "id": "NP_001074593" }, { "name": "Map7d2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "id": "NP_001074593" }, { "name": "Mtap7d2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprot/A2AG50", "id": "A2AG50" } ], "protein_names": [ { "name": "MAP7 domain-containing protein 2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprotkb/A2AG50/entry#names_and_taxonomy", "id": "A2AG50" }, { "name": "MAP7 domain-containing protein 2 isoform 1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "id": "NP_001074593" }, { "name": "MAP7 domain-containing protein 2; novel E-MAP-115 family protein", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "id": "NP_001074593" } ], "function": [], "disease": [], "snv": [ { "evidence": [ { "id": "rs3411185078", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs3411185078" } ], "glycoeffect": [ "n-glyco-sequon-gain", "o-glyco-site-loss" ], "start_pos": 261, "end_pos": 261, "sequence_org": "Y", "sequence_mut": "N", "comment": "Germline mutation passed 1 out of 1 filters: n-glyco-sequon-gain (YKS->NKS).", "chr_id": "X", "chr_pos": "158252985", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "Y261", "keywords": [ "ebi", "germline" ] } ], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "gene": [ { "name": "Map7d2", "url": "https://www.uniprot.org/uniprot/A2AG50", "locus": { "chromosome": "X", "start_pos": 158281753, "end_pos": 158197568, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSMUSG00000041020", "url": "https://www.ensembl.org/id/ENSMUSG00000041020" } ] } } ], "crossref": [ { "id": "ENSMUSG00000041020", "url": "https://bgee.org/?page=gene&gene_id=ENSMUSG00000041020", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "78283", "url": "https://www.ncbi.nlm.nih.gov/gene/78283", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "mmu:78283", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78283", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "1917474", "url": "http://www.informatics.jax.org/marker/MGI:1917474", "database": "MGI", "categories": [ "Organism-specific" ] }, { "id": "A2AG50", "url": "https://oglcnac.org/atlas/detail/A2AG50", "database": "O-GlcNAc Atlas", "categories": [ "Glycoproteomics" ] }, { "id": "A2AG50", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AG50", "database": "O-GlcNAc Database", "categories": [ "Glycoproteomics" ] }, { "id": "QVKNNTH", "url": "https://omabrowser.org/oma/group/QVKNNTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "4266661at2759", "url": "http://www.orthodb.org/?query=4266661at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15073", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15073", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15073:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15073:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05672", "url": "http://pfam.xfam.org/family/PF05672", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PR_A2AG50", "url": "http://purl.obolibrary.org/obo/PR_A2AG50", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001074593", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074593", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AG50-1", "url": "https://www.uniprot.org/uniprot/A2AG50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AG50-2", "url": "https://www.uniprot.org/uniprot/A2AG50-2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AG50-3", "url": "https://www.uniprot.org/uniprot/A2AG50-3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AG51", "url": "https://www.uniprot.org/uniprot/A2AG51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AG51-1", "url": "https://www.uniprot.org/uniprot/A2AG51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8C0A6", "url": "https://www.uniprot.org/uniprot/Q8C0A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q8C0A6-1", "url": "https://www.uniprot.org/uniprot/Q8C0A6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERSGGNGGGGGGGGGGGGGYGGSGGGGGGAGVPSEGAAKGLSLLLAKSAEAASGRASQSTPRSAGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSPGPGGRDGESENTPPLPLTLATSTPPLDTGTTTAAAESTNACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC", "length": 781, "header": "sp|A2AG50-1|MA7D2_MOUSE Isoform 1 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "isoforms": [ { "isoform_ac": "A2AG50-1", "url": "https://www.uniprot.org/uniprotkb/A2AG50/entry#A2AG50-1", "sequence": { "sequence": "MERSGGNGGGGGGGGGGGGGYGGSGGGGGGAGVPSEGAAKGLSLLLAKSAEAASGRASQSTPRSAGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSPGPGGRDGESENTPPLPLTLATSTPPLDTGTTTAAAESTNACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC", "length": 781, "header": "sp|A2AG50-1|MA7D2_MOUSE Isoform 1 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158279277, "end_pos": 158197693, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000112471.9", "url": "https://www.ensembl.org/id/ENSMUST00000112471.9" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000108090.3", "url": "https://www.ensembl.org/id/ENSMUSP00000108090.3" } ] } }, { "isoform_ac": "A2AG50-2", "url": "https://www.uniprot.org/uniprotkb/A2AG50/entry#A2AG50-2", "sequence": { "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVELQPPPDVENKANKAKPVVPNKIEINVLNTCQKVSGSERAAPETFPQDIFSTGLKPVGGPVHLDVLDGKSNSLDDSTEDVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC", "length": 597, "header": "sp|A2AG50-2|MA7D2_MOUSE Isoform 2 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158279277, "end_pos": 158242389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000043151.12", "url": "https://www.ensembl.org/id/ENSMUST00000043151.12" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000046693.6", "url": "https://www.ensembl.org/id/ENSMUSP00000046693.6" } ] } }, { "isoform_ac": "A2AG50-3", "url": "https://www.uniprot.org/uniprotkb/A2AG50/entry#A2AG50-3", "sequence": { "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERM", "length": 296, "header": "sp|A2AG50-3|MA7D2_MOUSE Isoform 3 of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158269425, "end_pos": 158242389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000112470.3", "url": "https://www.ensembl.org/id/ENSMUST00000112470.3" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000108089.2", "url": "https://www.ensembl.org/id/ENSMUSP00000108089.2" } ] } }, { "isoform_ac": "A2AG51-1", "url": "https://www.uniprot.org/uniprotkb/A2AG50/entry#A2AG51-1", "sequence": { "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDACDKLSTSTMNLPKQTESPMSKHLSSSTVAISYSPDRALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQMEKMKKGRVATSAASGGHGSPLRRCEPPEDISKRLSSPVKSKITSKTYPQSPKTAKPTYLGSPVKYYFPPIANEETPKKKAEKEKRNKEKEGAPGQQSTVLPREESLEKRMADKYATEKYVADKHATEKHSAPGGKAEHSAGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEERERLEKEELKRKAEEERLRIEMAYKREQEKKRQEEEEKRKAEEKAKEKAEEELLSKEKQEKEKQEQEKKEKAMIEKQKEAAEAKAQDAAKQMRLEREQIMLQIEQERLER", "length": 402, "header": "tr|A2AG51-1|MA7D2_MOUSE Computationally mapped isoform of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=2 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158273774, "end_pos": 158242389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000145142.8", "url": "https://www.ensembl.org/id/ENSMUST00000145142.8" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000122106.2", "url": "https://www.ensembl.org/id/ENSMUSP00000122106.2" } ] } }, { "isoform_ac": "Q8C0A6-1", "url": "https://www.uniprot.org/uniprotkb/A2AG50/entry#Q8C0A6-1", "sequence": { "sequence": "MMRRSLERTQQLELKKKCSWAGSPGPGGRDALGSPLKSSYKSSPTRTTEKKKNTPISAMGDAGKGAMAGGEPSQ", "length": 74, "header": "tr|Q8C0A6-1|MA7D2_MOUSE Computationally mapped isoform of MAP7 domain-containing protein 2 OS=Mus musculus OX=10090 GN=Map7d2 PE=1 SV=1 CANONICAL=A2AG50-1" }, "locus": { "chromosome": "X", "start_pos": 158253089, "end_pos": 158242389, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSMUST00000156172.3", "url": "https://www.ensembl.org/id/ENSMUST00000156172.3" }, { "database": "Ensembl Peptide", "id": "ENSMUSP00000119132.2", "url": "https://www.ensembl.org/id/ENSMUSP00000119132.2" } ] } } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "S", "relation": "attached", "comment": "O-GlcNAcylation", "start_pos": 307, "start_aa": "Ser", "end_pos": 307, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser307", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "A2AG50", "database": "O-GlcNAc Atlas", "url": "https://oglcnac.org/atlas/detail/A2AG50" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "site_category": "reported_with_glycan", "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "evidence": [ { "id": "22645316", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/22645316" }, { "id": "A2AG50", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AG50" } ] } ], "phosphorylation": [ { "start_pos": 170, "end_pos": 170, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser170" }, { "start_pos": 21, "end_pos": 21, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Tyr21" }, { "start_pos": 239, "end_pos": 239, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser239" }, { "start_pos": 240, "end_pos": 240, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser240" }, { "start_pos": 241, "end_pos": 241, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser241" }, { "start_pos": 242, "end_pos": 242, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Thr242" }, { "start_pos": 248, "end_pos": 248, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "phospho.ELM", "id": "A2AG50", "url": "http://phospho.elm.eu.org/byAccession/A2AG50.html" }, { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" }, { "database": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" } ], "site_lbl": "Ser248" }, { "start_pos": 24, "end_pos": 24, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser24" }, { "start_pos": 255, "end_pos": 255, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser255" }, { "start_pos": 263, "end_pos": 263, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser263" }, { "start_pos": 264, "end_pos": 264, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser264" }, { "start_pos": 266, "end_pos": 266, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Thr266" }, { "start_pos": 315, "end_pos": 315, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser315" }, { "start_pos": 331, "end_pos": 331, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser331" }, { "start_pos": 332, "end_pos": 332, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser332" }, { "start_pos": 354, "end_pos": 354, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Tyr354" }, { "start_pos": 357, "end_pos": 357, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser357" }, { "start_pos": 35, "end_pos": 35, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser35" }, { "start_pos": 371, "end_pos": 371, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Thr371" }, { "start_pos": 444, "end_pos": 444, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Thr444" }, { "start_pos": 4, "end_pos": 4, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser4" }, { "start_pos": 600, "end_pos": 600, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser600" }, { "start_pos": 683, "end_pos": 683, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser683" }, { "start_pos": 689, "end_pos": 689, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser689" }, { "start_pos": 699, "end_pos": 699, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser699" }, { "start_pos": 751, "end_pos": 751, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser751" }, { "start_pos": 756, "end_pos": 756, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser756" }, { "start_pos": 770, "end_pos": 770, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "site_lbl": "Ser770" } ], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Comprehensive identification of phosphorylation sites in postsynaptic density preparations.", "journal": "Mol. Cell. Proteomics", "date": "2006", "authors": "Trinidad JC, Specht CG, Thalhammer A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "UniProtKB", "id": "A2AG51", "url": "https://www.uniprot.org/uniprot/A2AG51" }, { "database": "iPTMnet", "id": "A2AG50", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/A2AG50" } ], "reference": [ { "type": "PubMed", "id": "16452087", "url": "https://glygen.org/publication/PubMed/16452087" } ] }, { "title": "Global identification and characterization of both O-GlcNAcylation and phosphorylation at the murine synapse.", "journal": "Molecular & cellular proteomics : MCP", "date": "2012", "authors": "Trinidad JC, Barkan DT, Gulledge BF, Thalhammer A, Sali A, Schoepfer R, Burlingame AL", "evidence": [ { "database": "O-GlcNAc Database", "id": "A2AG50", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A2AG50" }, { "database": "O-GlcNAc Atlas", "id": "A2AG50", "url": "https://oglcnac.org/atlas/detail/A2AG50" } ], "reference": [ { "type": "PubMed", "id": "22645316", "url": "https://glygen.org/publication/PubMed/22645316" } ] } ], "pathway": [ { "id": "mmu:78283", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+mmu:78283", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2RGI0-1", "protein_name": "MAP7 domain containing 2", "gene_name": "MAP7D2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAETGRAAAARGAEEGCRGGEEEAEAPGGGGAAGGDDAQSLERTQQLELKKKYSWGPSLASGTGGRDACDKLSTSAMNLPKQTEPPMSKRLSSSTAAISYSPDRAHRMHLSPMETFLVMRLLTPTQASLARSRSALMLSEQAGDSVSHACPRLAPAGGPLKSSYKSSPTRNAERKKTTSTSGVGDAGKGAPAGAEASPTEKMKRGPRTTTSVPGVGLMSPLKRCDFPTGVSKRSSSPVTPKATPKAYPQSPKNAKPPYLGSPVKYRLPAFSGQETPKKKADKEKSNKEREGALAQQAAGLPGEEAPEKHVADRHATEKHASGKAEGAGASWKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQQRLEKEEQDRLQREELKRKAEEERRRLEEEARRQEEEKKRREEEEERKAAAEAKRRAKEELLLKEEQEKEKQEKEKQEKVVIEKQKEAAEAKAQEAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVSLEVKKEEPKVELQPAVCVENKIKPVVPSKIEINGLNTCQEVNGVERAAPETFPQDVFANGLKPAGGLVHLDALDGKSNSLDDSTEEVQSMDVSPVSKEELISIPEFSPVNEMIPGVSLDQNGTGNARALQDLLDFTGPPIFPKRSSENLSLDDCNKNLIEGFNSPGQENTLNTFC", "length": 673 }, "evidence": [ { "id": "A2AG50", "url": "https://omabrowser.org/oma/group/A2AG50/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A4L4-1", "protein_name": "MAP7 domain containing 2", "gene_name": "Map7d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERSGGNGAGARAGAPSEGAAKGSSLLSAKSTEGATGRFSQSTPRPTGMDGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRAKLQYEKQIEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKCSWAGSAASGPGGRDGESENTPPLPLTLAASIPPSDTGTATAAAESTNACDKLSTSTMNLPKQTEPPMSKHLSSSIVAISYSPDRALRSPLKSSYKSSPTRTTEKKKNTLLSGVGDAGKGAMTGGEPSQMEKVKKGRGATSVSSGGLGSPLRRCEPPENISKRSSSPVKSKVTAKTYPQSPKTVKPTYIGSPVKYYFPPTPSEETLKKKAEKEKSNKEKEGATGRQTTVLPREETLEKPMADKDATEKYVADKHATEKHSATGGKAEHSAGKSTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQERLEKEELKRKAEEERLRIEKQEEEKKQQEEEEKRKAEEKAKEKAEEELLSKEEQEKEKQEKEKKEKAMIEKQIQAEKEAAEAKAQDAAKQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDASLEVKKEDPKVEIQPLPDVENKIKPVVPNKIEINVLNTCQKVNVSERAAPETFPQDIFSNGLKPVGGPVHPDVLDGKSNSLDDSTEEVQSMDVSPVSKEELISIPEFSPVSEMIPGMSLDQNGTGNARALQDILDFTGPPAFPKKSSENLSLDDCNKNLIEGFNSPGQETTLNTFC", "length": 763 }, "evidence": [ { "id": "46367290", "url": "http://www.informatics.jax.org/homology/46367290", "database": "MGI" }, { "id": "A2AG50", "url": "https://omabrowser.org/oma/group/A2AG50/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96T17-1", "protein_name": "MAP7 domain-containing protein 2", "gene_name": "MAP7D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERGGGGSGTGSRPEGTARGTSLPGKIAEPGAVRTSQPNYRPQGMEGFLKSDERQRLAKERREEREKCLAAREQQILEKQKRARLQYEKQMEERWRKLEEQRQREDQKRAAVEEKRKQKLREEEERLEAMMRRSLERTQQLELKKKYSWGAPLAIGPGGHDACDKLSTSTMSLPKPTEPPMNKRLSSSTVAISYSPDRVFHVCPRLAPLGPLNPSYKSSPTRNIEKKKATSTSTSGAGDVGKEALSGGEASLVEKVKRGQRTATSLPVVNFGSPLRRCEFSGGIPKRPSSPVISKTATKAYPQSPKTTKPPYPGSPVKYRLPALSGQDMPKRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKPTAGTTDAGEAAKILAEKRRQARLQKEQEEQERLEKEEQDRLEREELKRKAEEERLRLEEEARKQEEERKRQEEEKKKQEGEEKRKAGEEAKRKAEEELLLKEKQEQEKQEKAMIEKQKEAAETKAREVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTRKSDVSPQVKKEDPKVGVQPAVCVEKKTKLVVPNKMEINGLNTCQEVNGVDHAAPETYPQDIFSNGLKPAGGLIHLDALDGKSNSLDDSTEEVQSMDVSPVSKEELISIPEFSPVSEMIPGVSLDQNGTGNARALQDLLDFTGPPTFPKRSSENLSLDDCNKNLIEGFNSPGQETPLNTFC", "length": 732 }, "evidence": [ { "id": "46367290", "url": "http://www.informatics.jax.org/homology/46367290", "database": "MGI" }, { "id": "A2AG50", "url": "https://omabrowser.org/oma/group/A2AG50/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A2AG50", "url": "https://www.uniprot.org/uniprot/A2AG50" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 727, "end_pos": 729, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.mgi", "label": "MGI Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 307 ], "snv_sites": [ 261 ], "glycation_sites": [], "phosphorylation_sites": [ 4, 21, 24, 35, 170, 239, 240, 241, 242, 248, 255, 263, 264, 266, 315, 331, 332, 354, 357, 371, 444, 600, 683, 689, 699, 751, 756, 770 ], "sequon_annotation_sites": [ { "start_pos": 727, "end_pos": 729 }, { "start_pos": 754, "end_pos": 756 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 2 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 28 }, { "field": "total_sites", "count": 28 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }