{
    "uniprot_canonical_ac": "A0A8V0ZIH4-1",
    "uniprot_ac": "A0A8V0ZIH4",
    "uniprot_id": "A0A8V0ZIH4_CHICK",
    "mass": {
        "chemical_mass": 55406.0,
        "monoisotopic_mass": 55406.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "CHRNA1",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4",
            "id": "A0A8V0ZIH4"
        }
    ],
    "protein_names": [
        {
            "name": "Cholinergic receptor nicotinic alpha 1 subunit",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH4/entry#names_and_taxonomy",
            "id": "A0A8V0ZIH4"
        }
    ],
    "function": [
        {
            "annotation": "Upon acetylcholine binding, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8V0ZW98",
                    "url": "https://www.uniprot.org/uniprot/A0A8V0ZW98#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00037634",
                    "url": "https://www.uniprot.org/uniprot/ARBA00037634#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A8V0ZIH4",
                    "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A8V0ZR98",
                    "url": "https://www.uniprot.org/uniprot/A0A8V0ZR98#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "A0A8V0ZIG3",
                    "url": "https://www.uniprot.org/uniprot/A0A8V0ZIG3#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Gallus gallus",
            "taxid": 9031,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A8V0ZIH4",
                    "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4"
                }
            ],
            "common_name": "Chicken",
            "glygen_name": "Chicken",
            "reference_species": "Gallus gallus [9031]"
        }
    ],
    "gene": [
        {
            "name": "CHRNA1",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4",
            "locus": {
                "chromosome": "7",
                "start_pos": 16434136,
                "end_pos": 16423649,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSGALG00010022515",
                        "url": "https://www.ensembl.org/id/ENSGALG00010022515"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "cd19014",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19014",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "cd19064",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19064",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR002394",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002394",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006029",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006029",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006201",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR006202",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018000",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018000",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036719",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR036734",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR038050",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR18945",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR18945:SF74",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945:SF74",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF02931",
            "url": "http://pfam.xfam.org/family/PF02931",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF02932",
            "url": "http://pfam.xfam.org/family/PF02932",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A8V0ZIG3",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZIG3",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZIG3-1",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZIG3-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZIH4",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZIH4-1",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZR98",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZR98",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZR98-1",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZR98-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZW98",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZW98",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A8V0ZW98-1",
            "url": "https://www.uniprot.org/uniprot/A0A8V0ZW98-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MCCFFCFLCYKRELASSLLANAADKYGRELPACKGAKSTWSVAAGSALCYEHETRLVDDLFRDYSKVVRPVENHRDAVVVTVGLQLIQLINVDEVNQIVTTNVRLKQQWTDINLKWNPDDYGGVKQIRIPSDDIWRPDLVLYNNADGDFAIVKYTKVLLEHTGKITWTPPAIFKSYCEIIVTYFPFDQQNCSMKLGTWTYDGTMVVINPESDRPDLSNFMESGEWVMKDYRGWKHWVYYACCPDTPYLDITYHFLMQRLPLYFIVNVIIPCLLFSFLTGFVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHTMPPWVRKIFIDTIPNIMFFSTMKRPSRDKPDKKIFAEDIDISEISGKQGPVPVNFYSPLTKNPDVKNAIEGIKYIAETMKSDQESSNAADEWKFVAMVLDHLLLVIFMLVCIIGTLAVFAGRLIELNQQG",
        "length": 486,
        "header": "tr|A0A8V0ZIH4-1|A0A8V0ZIH4_CHICK Isoform 1 of Cholinergic receptor nicotinic alpha 1 subunit  OS=Gallus gallus OX=9031 GN=CHRNA1 PE=3 SV=1 CANONICAL=A0A8V0ZIH4-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A8V0ZIG3-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH4/entry#A0A8V0ZIG3-1",
            "sequence": {
                "sequence": "MELCRVLLLIFSAAGSALCYEHETRLVDDLFRDYSKVVRPVENHRDAVVVTVGLQLIQLINVQWTDINLKWNPDDYGGVKQIRIPSDDIWRPDLVLYNNADGDFAIVKYTKVLLEHTGKITWTPPAIFKSYCEIIVTYFPFDQQNCSMKLGTWTYDGTMVVINPESDRPDLSNFMESGEWVMKDYRGWKHWVYYACCPDTPYLDITYHFLMQRLPLYFIVNVIIPCLLFSFLTGFVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHTMPPWVRKIFIDTIPNIMFFSTMKRPSRDKPDKKIFAEDIDISEISGKQGPVPVNFYSPLTKNPDVKNAIEGIKYIAETMKSDQESSNAADEWKFVAMVLDHLLLVIFMLVCIIGTLAVFAGRLIELNQQG",
                "length": 441,
                "header": "tr|A0A8V0ZIG3-1|A0A8V0ZIG3_CHICK Computationally mapped isoform of Cholinergic receptor nicotinic alpha 1 subunit  OS=Gallus gallus OX=9031 GN=CHRNA1 PE=3 SV=1 CANONICAL=A0A8V0ZIH4-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 16432937,
                "end_pos": 16426366,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010054806.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010054806.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010033123.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010033123.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8V0ZIH4-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH4/entry#A0A8V0ZIH4-1",
            "sequence": {
                "sequence": "MCCFFCFLCYKRELASSLLANAADKYGRELPACKGAKSTWSVAAGSALCYEHETRLVDDLFRDYSKVVRPVENHRDAVVVTVGLQLIQLINVDEVNQIVTTNVRLKQQWTDINLKWNPDDYGGVKQIRIPSDDIWRPDLVLYNNADGDFAIVKYTKVLLEHTGKITWTPPAIFKSYCEIIVTYFPFDQQNCSMKLGTWTYDGTMVVINPESDRPDLSNFMESGEWVMKDYRGWKHWVYYACCPDTPYLDITYHFLMQRLPLYFIVNVIIPCLLFSFLTGFVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHTMPPWVRKIFIDTIPNIMFFSTMKRPSRDKPDKKIFAEDIDISEISGKQGPVPVNFYSPLTKNPDVKNAIEGIKYIAETMKSDQESSNAADEWKFVAMVLDHLLLVIFMLVCIIGTLAVFAGRLIELNQQG",
                "length": 486,
                "header": "tr|A0A8V0ZIH4-1|A0A8V0ZIH4_CHICK Isoform 1 of Cholinergic receptor nicotinic alpha 1 subunit  OS=Gallus gallus OX=9031 GN=CHRNA1 PE=3 SV=1 CANONICAL=A0A8V0ZIH4-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 16432937,
                "end_pos": 16423848,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010054818.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010054818.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010033133.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010033133.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8V0ZR98-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH4/entry#A0A8V0ZR98-1",
            "sequence": {
                "sequence": "MELCRVLLLIFSAAGSALCYEHETRLVDDLFRDYSKVVRPVENHRDAVVVTVGLQLIQLINVDEVNQIVTTNVRQWTDINLKWNPDDYGGVKQIRIPSDDIWRPDLVLYNNADGDFAIVKYTKVLLEHTGKITWTPPAIFKSYCEIIVTYFPFDQQNCSMKLGTWTYDGTMVVINPESDRPDLSNFMESGEWVMKDYRGWKHWVYYACCPDTPYLDITYHFLMQRLPLYFIVNVIIPCLLFSFLTGFVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHTMPPWVRKIFIDTIPNIMFFSTMKRPSRDKPDKKIFAEDIDISEISGKQGPVPVNFYSPLTKNPDVKNAIEGIKYIAETMKSDQESSNAADEWKFVAMVLDHLLLVIFMLVCIIGTLAVFAGRLIELNQQG",
                "length": 453,
                "header": "tr|A0A8V0ZR98-1|A0A8V0ZR98_CHICK Computationally mapped isoform of Cholinergic receptor nicotinic alpha 1 subunit  OS=Gallus gallus OX=9031 GN=CHRNA1 PE=3 SV=1 CANONICAL=A0A8V0ZIH4-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 16432937,
                "end_pos": 16426366,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010054796.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010054796.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010033116.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010033116.1"
                    }
                ]
            }
        },
        {
            "isoform_ac": "A0A8V0ZW98-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A8V0ZIH4/entry#A0A8V0ZW98-1",
            "sequence": {
                "sequence": "MCYRHMVLLSSFNPNACYLCLLSLFLFFPFKDEVNQIVTTNVRLKQQWTDINLKWNPDDYGGVKQIRIPSDDIWRPDLVLYNNADGDFAIVKYTKVLLEHTGKITWTPPAIFKSYCEIIVTYFPFDQQNCSMKLGTWTYDGTMVVINPESDRPDLSNFMESGEWVMKDYRGWKHWVYYACCPDTPYLDITYHFLMQRLPLYFIVNVIIPCLLFSFLTGFVFYLPTDSGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIVINTHHRSPSTHTMPPWVRKIFIDTIPNIMFFSTMKRPSRDKPDKKIFAEDIDISEISGKQGPVPVNFYSPLTKNPDVKNAIEGIKYIAETMKSDQESSNAADEWKFVAMVLDHLLLVIFMLVCIIGTLAVFAGRLIELNQQG",
                "length": 425,
                "header": "tr|A0A8V0ZW98-1|A0A8V0ZIH4_CHICK Computationally mapped isoform of Cholinergic receptor nicotinic alpha 1 subunit  OS=Gallus gallus OX=9031 GN=CHRNA1 PE=3 SV=1 CANONICAL=A0A8V0ZIH4-1"
            },
            "locus": {
                "chromosome": "7",
                "start_pos": 16432937,
                "end_pos": 16427240,
                "strand": "-",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010054812.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010054812.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010033129.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010033129.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [],
    "orthologs": [],
    "go_annotation": {
        "categories": [
            {
                "name": "Molecular Function",
                "total": 2,
                "go_terms": [
                    {
                        "name": "transmembrane signaling receptor activity",
                        "id": "GO:0004888",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8V0ZIH4",
                                "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "acetylcholine-gated monoatomic cation-selective channel activity",
                        "id": "GO:0022848",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022848",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8V0ZIH4",
                                "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "postsynaptic membrane",
                        "id": "GO:0045211",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A8V0ZIH4",
                                "url": "https://www.uniprot.org/uniprot/A0A8V0ZIH4"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            }
        ]
    },
    "pro_annotation": [],
    "site_annotation": [
        {
            "start_pos": 190,
            "end_pos": 192,
            "annotation": "n_glycosylation_sequon"
        }
    ],
    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "enzyme_annotation": [],
    "cluster_types": [
        {
            "name": "isoformset.uniprotkb",
            "label": "Isoforms"
        }
    ],
    "sequence_features": {
        "n_linked_sites": [],
        "o_linked_sites": [],
        "snv_sites": [],
        "glycation_sites": [],
        "phosphorylation_sites": [],
        "sequon_annotation_sites": [
            {
                "start_pos": 190,
                "end_pos": 192
            }
        ]
    },
    "section_stats": [
        {
            "table_id": "glycosylation",
            "table_stats": [
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                    "field": "total",
                    "count": 0
                },
                {
                    "field": "total_sites",
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                {
                    "field": "n_linked_glycans",
                    "count": 0
                },
                {
                    "field": "n_linked_glycan_sites",
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                },
                {
                    "field": "o_linked_glycans",
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                {
                    "field": "o_linked_glycan_sites",
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            "sort_fields": []
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        {
            "table_id": "glycosylation_reported",
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        {
            "table_id": "glycosylation_reported_with_glycan",
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        {
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            "table_id": "glycosylation_automatic_literature_mining",
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            ],
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        {
            "table_id": "snv",
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        {
            "table_id": "snv_disease",
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