{ "uniprot_canonical_ac": "A0A8D0IPU6-1", "uniprot_ac": "A0A8D0IPU6", "uniprot_id": "A0A8D0IPU6_PIG", "mass": { "chemical_mass": 41936.0, "monoisotopic_mass": 41936.0 }, "refseq": { "ac": "XP_001924354", "name": "dnaJ homolog subfamily B member 12 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924354" }, "gene_names": [ { "name": "DNAJB12", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6", "id": "A0A8D0IPU6" }, { "name": "DNAJB12", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924354", "id": "XP_001924354" } ], "protein_names": [ { "name": "DnaJ heat shock protein family (Hsp40) member B12", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IPU6/entry#names_and_taxonomy", "id": "A0A8D0IPU6" }, { "name": "dnaJ homolog subfamily B member 12 isoform X2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924354", "id": "XP_001924354" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "DNAJB12", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6", "locus": { "chromosome": "14", "start_pos": 75169077, "end_pos": 75189883, "strand": "+", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000010288", "url": "https://www.ensembl.org/id/ENSSSCG00000010288" } ] } } ], "crossref": [ { "id": "ENSSSCG00000010288", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000010288", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100156234", "url": "https://www.ncbi.nlm.nih.gov/gene/100156234", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015399", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015399", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ssc:100156234", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ssc:100156234", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARSREHN", "url": "https://omabrowser.org/oma/group/ARSREHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "2785358at2759", "url": "http://www.orthodb.org/?query=2785358at2759", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43908", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43908", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43908:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43908:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "http://pfam.xfam.org/family/PF00226", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF09320", "url": "http://pfam.xfam.org/family/PF09320", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_001924354", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001924354", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8D0IPU6-1", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MESNKDEAERCISIALKAIQSNQHDRALRFLEKAQRLYPTPRVRALIESLNQKPQSAGDQPQSTEATHATHRKAGGASSPSANGEAGGGESTKGYTAEQVAAVKRVKQCKDYYEILGVSRGASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARQGHGHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYAYHQRQDRRENQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSLRPSVGHVHKRVTDHLNVVYYVADTFSEEYTGSSLKMVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHKAQKMGTPSCNRLSEVQASLHG", "length": 376, "header": "tr|A0A8D0IPU6-1|A0A8D0IPU6_PIG Isoform 1 of DnaJ heat shock protein family (Hsp40) member B12 OS=Sus scrofa OX=9823 GN=DNAJB12 PE=4 SV=1 CANONICAL=A0A8D0IPU6-1" }, "isoforms": [ { "isoform_ac": "A0A8D0IPU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8D0IPU6/entry#A0A8D0IPU6-1", "sequence": { "sequence": "MESNKDEAERCISIALKAIQSNQHDRALRFLEKAQRLYPTPRVRALIESLNQKPQSAGDQPQSTEATHATHRKAGGASSPSANGEAGGGESTKGYTAEQVAAVKRVKQCKDYYEILGVSRGASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARQGHGHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYAYHQRQDRRENQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSLRPSVGHVHKRVTDHLNVVYYVADTFSEEYTGSSLKMVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHKAQKMGTPSCNRLSEVQASLHG", "length": 376, "header": "tr|A0A8D0IPU6-1|A0A8D0IPU6_PIG Isoform 1 of DnaJ heat shock protein family (Hsp40) member B12 OS=Sus scrofa OX=9823 GN=DNAJB12 PE=4 SV=1 CANONICAL=A0A8D0IPU6-1" }, "locus": { "chromosome": "14", "start_pos": 75189670, "end_pos": 75172068, "strand": "+", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSSSCT00000011260.5", "url": "https://www.ensembl.org/id/ENSSSCT00000011260.5" }, { "database": "Ensembl Peptide", "id": "ENSSSCP00000010968.4", "url": "https://www.ensembl.org/id/ENSSSCP00000010968.4" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "ssc:100156234", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+ssc:100156234", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7F4L4-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member B12", "gene_name": "Dnajb12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVTALIESLNQKSQSAGDQSQPTDTTHTTTRKTSGTETPSANGEAGGGESTKGYTSEQVAAVKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKNQAARHGHSHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMSTPSCSRLSEVQASLHG", "length": 376 }, "evidence": [ { "id": "A0A8D0IPU6", "url": "https://omabrowser.org/oma/group/A0A8D0IPU6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NXW2-1", "protein_name": "DnaJ homolog subfamily B member 12", "gene_name": "DNAJB12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESNKDEAERCISIALKAIQSNQPDRALRFLEKAQRLYPTPRVRALIESLNQKPQTAGDQPPPTDTTHATHRKAGGTDAPSANGEAGGESTKGYTAEQVAAVKRVKQCKDYYEILGVSRGASDEDLKKAYRRLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHGHGHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHRRVTDHLGVVYYVGDTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCSRLSEVQASLHG", "length": 375 }, "evidence": [ { "id": "A0A8D0IPU6", "url": "https://omabrowser.org/oma/group/A0A8D0IPU6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYI4-1", "protein_name": "DnaJ homolog subfamily B member 12", "gene_name": "Dnajb12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESNKDEAERCISIALKAIQSNQPERALRFLEKAQRLYPTPRVSALIESLNQKPQSTGDHPQPTDTTHTTTKKAGGTETPSANGEAGGGESAKGYTSEQVAAVKRVKQCKDYYEILGVSRSASDEDLKKAYRKLALKFHPDKNHAPGATEAFKAIGTAYAVLSNPEKRKQYDQFGDDKSQAARHGHSHGDFHRGFEADISPEDLFNMFFGGGFPSSNVHVYSNGRMRYTYQQRQDRRDNQGDGGLGVFVQLMPILILILVSALSQLMVSSPPYSLSPRPSVGHIHKRVTDHLNVAYYVADTFSEEYTGSSLKTVERNVEDDYIANLRNNCWKEKQQKEGLLYRARYFGDTDMYHRAQKMGTPSCNRLSEVQASLHG", "length": 376 }, "evidence": [ { "id": "A0A8D0IPU6", "url": "https://omabrowser.org/oma/group/A0A8D0IPU6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VFP0-1", "protein_name": "RH07106p", "gene_name": "Dmel\\CG3061", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDGNKDEAQRCIDFAVQALAAGKIEKAEKFLLKAERLFPTDNAKKLLAQLKSTPSNESNGKSRTAGASDEKDSGPRKRVNSDSRSSAPDYTKDQLEAVRKVKTCKDYYEVLGVSKTATDSEIKKAYKKLALQLHPDKNKAPGAVEAFKALGNAAGVLTDAEKRKNYDLYGINESHNGHGNNGGGHHGHGQYYNNEYGYSRGFQADISAEELFNMFFNGGFPQQNVHMRQQRRRQQAREDREGNNSSALVNLLPIVLLIGLSMMSSFFISDPMYSLTPSHKYSVKRETNSLKVPYYVKDNFYSEYQGSVARLEESVEEDFVNHLKHSCSRERNYRDSMLAKARTFGDRDLYRKAQNINTPSCENLQKYLIT", "length": 370 }, "evidence": [ { "id": "A0A8D0IPU6", "url": "https://omabrowser.org/oma/group/A0A8D0IPU6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6" } ], "pmid": "" }, { "name": "chaperone cofactor-dependent protein refolding", "id": "GO:0051085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051085", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6" } ], "pmid": "" }, { "name": "cellular response to misfolded protein", "id": "GO:0071218", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071218", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6" } ], "pmid": "" }, { "name": "protein-containing complex assembly", "id": "GO:0065003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0065003", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "Hsp70 protein binding", "id": "GO:0030544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030544", "evidence": [ { "database": "UniProtKB", "id": "A0A8D0IPU6", "url": "https://www.uniprot.org/uniprot/A0A8D0IPU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }