{
    "uniprot_canonical_ac": "A0A4P9IVJ2-1",
    "uniprot_ac": "A0A4P9IVJ2",
    "uniprot_id": "A0A4P9IVJ2_CHICK",
    "mass": {
        "chemical_mass": 42496.0,
        "monoisotopic_mass": 42496.0
    },
    "refseq": {
        "ac": "XP_004947106",
        "name": "thyrotropin-releasing hormone receptor",
        "summary": "",
        "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947106"
    },
    "gene_names": [
        {
            "name": "TRHR3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A4P9IVJ2",
            "id": "A0A4P9IVJ2"
        },
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            "name": "LOC428144",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947106",
            "id": "XP_004947106"
        },
        {
            "name": "LOC428144",
            "resource": "UniProtKB",
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            "id": "A0A4P9IVJ2"
        }
    ],
    "protein_names": [
        {
            "name": "Thyrotropin-releasing hormone receptor",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A4P9IVJ2/entry#names_and_taxonomy",
            "id": "A0A4P9IVJ2"
        },
        {
            "name": "Thyroliberin receptor",
            "resource": "UniProtKB",
            "type": "synonym",
            "url": "https://www.uniprot.org/uniprotkb/A0A4P9IVJ2/entry#names_and_taxonomy",
            "id": "A0A4P9IVJ2"
        },
        {
            "name": "thyrotropin-releasing hormone receptor",
            "resource": "RefSeq",
            "type": "synonym",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947106",
            "id": "XP_004947106"
        }
    ],
    "function": [
        {
            "annotation": "Receptor for thyrotropin-releasing hormone (TRH). Upon ligand binding, this G-protein-coupled receptor triggers activation of the phosphatidylinositol (IP3)-calcium-protein kinase C (PKC) pathway.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A4P9IVJ2",
                    "url": "https://www.uniprot.org/uniprot/A0A4P9IVJ2#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "ARBA00004100",
                    "url": "https://www.uniprot.org/uniprot/ARBA00004100#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Gallus gallus",
            "taxid": 9031,
            "evidence": [
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                    "database": "UniProtKB",
                    "id": "A0A4P9IVJ2",
                    "url": "https://www.uniprot.org/uniprot/A0A4P9IVJ2"
                }
            ],
            "common_name": "Chicken",
            "glygen_name": "Chicken",
            "reference_species": "Gallus gallus [9031]"
        }
    ],
    "gene": [
        {
            "name": "TRHR3",
            "url": "https://www.uniprot.org/uniprot/A0A4P9IVJ2",
            "locus": {}
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    ],
    "crossref": [
        {
            "id": "cd14995",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14995",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
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            "url": "https://www.ncbi.nlm.nih.gov/gene/428144",
            "database": "GeneID",
            "categories": [
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        },
        {
            "id": "IPR000276",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR002120",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR002120",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR017452",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "gga:428144",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+gga:428144",
            "database": "KEGG Pathway",
            "categories": [
                "Enzyme and Pathway"
            ]
        },
        {
            "id": "MWFFLAD",
            "url": "https://omabrowser.org/oma/group/MWFFLAD/",
            "database": "OMA",
            "categories": [
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            ]
        },
        {
            "id": "3471593at2759",
            "url": "http://www.orthodb.org/?query=3471593at2759",
            "database": "OrthoDB",
            "categories": [
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            ]
        },
        {
            "id": "PTHR46061",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46061",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR46061:SF1",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46061:SF1",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00001",
            "url": "http://pfam.xfam.org/family/PF00001",
            "database": "Pfam",
            "categories": [
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            ]
        },
        {
            "id": "XP_004947106",
            "url": "https://www.ncbi.nlm.nih.gov/protein/XP_004947106",
            "database": "RefSeq",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A4P9IVJ2",
            "url": "https://www.uniprot.org/uniprot/A0A4P9IVJ2",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A4P9IVJ2-1",
            "url": "https://www.uniprot.org/uniprot/A0A4P9IVJ2-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MENGSASPGATLGNQTLGRMPRQPLELQVVTILLVLLVCGVGIAGNAMVVLVVLRTKHMVTPTNCYLVSLAVADLLVLLVAGLPNISEVVASWVYGYAGCLCITYLQYLGINISAWSITAFTVERYIAICHAIRAQLLCTVARAKRIISSLWIFTSVYCLVWFFLVDTSQVTFSDGEQVSCGYRVSRSLYMPIYFLDFAVFYVIPLGLAAVLYGLIARILYMSPLPAAPQHALGSAHRGGSLQQSCQGSRGTLSSRKQVTKMLAVVVVLFALLWLPYRTLVVVNSFVDPPYLNIWFLLFCRMCIYLNSAINPIIYSLMSQRFRAAFRKLCRCGWKSTEVPTPRSVPVLYSRAKDGSQGSSEHGTHQDDLNGPPAPVRSRAAMHTPGP",
        "length": 387,
        "header": "tr|A0A4P9IVJ2-1|A0A4P9IVJ2_CHICK Isoform 1 of Thyrotropin-releasing hormone receptor  OS=Gallus gallus OX=9031 GN=TRHR3 PE=2 SV=1 CANONICAL=A0A4P9IVJ2-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A4P9IVJ2-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A4P9IVJ2/entry#A0A4P9IVJ2-1",
            "sequence": {
                "sequence": "MENGSASPGATLGNQTLGRMPRQPLELQVVTILLVLLVCGVGIAGNAMVVLVVLRTKHMVTPTNCYLVSLAVADLLVLLVAGLPNISEVVASWVYGYAGCLCITYLQYLGINISAWSITAFTVERYIAICHAIRAQLLCTVARAKRIISSLWIFTSVYCLVWFFLVDTSQVTFSDGEQVSCGYRVSRSLYMPIYFLDFAVFYVIPLGLAAVLYGLIARILYMSPLPAAPQHALGSAHRGGSLQQSCQGSRGTLSSRKQVTKMLAVVVVLFALLWLPYRTLVVVNSFVDPPYLNIWFLLFCRMCIYLNSAINPIIYSLMSQRFRAAFRKLCRCGWKSTEVPTPRSVPVLYSRAKDGSQGSSEHGTHQDDLNGPPAPVRSRAAMHTPGP",
                "length": 387,
                "header": "tr|A0A4P9IVJ2-1|A0A4P9IVJ2_CHICK Isoform 1 of Thyrotropin-releasing hormone receptor  OS=Gallus gallus OX=9031 GN=TRHR3 PE=2 SV=1 CANONICAL=A0A4P9IVJ2-1"
            },
            "locus": {
                "chromosome": "20",
                "start_pos": 5879797,
                "end_pos": 5874316,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Transcript",
                        "id": "ENSGALT00010051976.1",
                        "url": "https://www.ensembl.org/id/ENSGALT00010051976.1"
                    },
                    {
                        "database": "Ensembl Peptide",
                        "id": "ENSGALP00010031022.1",
                        "url": "https://www.ensembl.org/id/ENSGALP00010031022.1"
                    }
                ]
            }
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [],
    "pathway": [
        {
            "id": "gga:428144",
            "name": "",
            "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+gga:428144",
            "resource": "KEGG Pathway"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A0A287BT79-1",
            "protein_name": "Thyrotropin-releasing hormone receptor",
            "gene_name": "LOC100738769",
            "tax_id": 9823,
            "organism": "Sus scrofa",
            "sequence": {
                "sequence": "EVQRGQGRMEKPTEHPERVNNASSLGPMPRPPLAVQAVTLTLVPLVCTVGVVGNAMVVLVVVRSRHMVTSTNCYLVSLATADLLVLLAAGVPTVAEAASARVWVFGHAGCLGITYLQYVGINASTGSITAFTVERYLAICRPLRAQALCTVARAKRIAASVWLGTGAYCVLWLFLVDTRETAYADGVQVQCGYRPRPAGGDLGRSGSAHQGGPAGPGRSSSRGRRGAFNSQKQVAKMLGVVVVLFALLWLPYRTLVVVNSFLSPPYLNLGFLLFCRLCIYLNSAINPIVYALMSQRFREAFHGLFRCRLAQSKLPPEEATPVYYSVIKDCPQHRLGSWKEPGSLMSRQGGDPGTSGQGPPSYPY",
                "length": 364
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            "evidence": [
                {
                    "id": "A0A4P9IVJ2",
                    "url": "https://omabrowser.org/oma/group/A0A4P9IVJ2/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Pig",
            "common_name": "Pig"
        }
    ],
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            {
                "name": "Cellular Component",
                "total": 1,
                "go_terms": [
                    {
                        "name": "membrane",
                        "id": "GO:0016020",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020",
                        "evidence": [
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                                "id": "A0A4P9IVJ2",
                                "url": "https://www.uniprot.org/uniprot/A0A4P9IVJ2"
                            }
                        ],
                        "pmid": ""
                    }
                ]
            },
            {
                "name": "Molecular Function",
                "total": 1,
                "go_terms": [
                    {
                        "name": "thyrotropin-releasing hormone receptor activity",
                        "id": "GO:0004997",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004997",
                        "evidence": [
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            "end_pos": 114,
            "annotation": "n_glycosylation_sequon"
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    "ptm_annotation": [],
    "interactions": [],
    "reactions": [],
    "reaction_participants": [],
    "reaction_enzymes": [],
    "biomarkers": [],
    "synthesized_glycans": [],
    "enzyme_annotation": [],
    "cluster_types": [
        {
            "name": "homologset.oma",
            "label": "OMA Homologs"
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    "sequence_features": {
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        "glycation_sites": [],
        "phosphorylation_sites": [],
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