{ "uniprot_canonical_ac": "A0A3Q2TYJ2-1", "uniprot_ac": "A0A3Q2TYJ2", "uniprot_id": "A0A3Q2TYJ2_CHICK", "mass": { "chemical_mass": 204611.0, "monoisotopic_mass": 204611.0 }, "refseq": { "ac": "XP_015149932", "name": "tuberin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149932" }, "gene_names": [ { "name": "TSC2", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2", "id": "A0A3Q2TYJ2" }, { "name": "TSC2", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149932", "id": "XP_015149932" } ], "protein_names": [ { "name": "TSC complex subunit 2", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYJ2/entry#names_and_taxonomy", "id": "A0A3Q2TYJ2" }, { "name": "tuberin isoform X1", "resource": "RefSeq", "type": "synonym", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149932", "id": "XP_015149932" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Gallus gallus", "taxid": 9031, "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "common_name": "Chicken", "glygen_name": "Chicken", "reference_species": "Gallus gallus [9031]" } ], "gene": [ { "name": "TSC2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2", "locus": { "chromosome": "14", "start_pos": 6302587, "end_pos": 6272243, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSGALG00010017930", "url": "https://www.ensembl.org/id/ENSGALG00010017930" } ] } } ], "crossref": [ { "id": "ENSGALG00000005646", "url": "https://bgee.org/?page=gene&gene_id=ENSGALG00000005646", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "416552", "url": "https://www.ncbi.nlm.nih.gov/gene/416552", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "gga:416552", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+gga:416552", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDIMSAI", "url": "https://omabrowser.org/oma/group/CDIMSAI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR10063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10063:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10063:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02145", "url": "http://pfam.xfam.org/family/PF02145", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF03542", "url": "http://pfam.xfam.org/family/PF03542", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF11864", "url": "http://pfam.xfam.org/family/PF11864", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "XP_015149932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_015149932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A1D5PM46", "url": "https://www.uniprot.org/uniprot/A0A1D5PM46", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A1D5PM46-1", "url": "https://www.uniprot.org/uniprot/A0A1D5PM46-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A3Q2TYJ2-1", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5G1", "url": "https://www.uniprot.org/uniprot/A0A8V0Z5G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8V0Z5G1-1", "url": "https://www.uniprot.org/uniprot/A0A8V0Z5G1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKPQSKDSGLKEKFKNLLGLGTSRGSSKSSEGKQTEFIITAEILKELSIECGLSNRIRAISQICEVAKTKKIEEHAVEAIWKVVADMLQPERPAEARHAVLHLLKSIIQGQGERLGILRAHFFKVIKDYPSNEDLHERLEVFKALTENGRYITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLEDYVADMVHKICILCIQTSSSVDIEISLQVLDAVVCYNCLPSENLPVFIITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMADAALLRGAVFFVGMALWGAHRLNSLKNSPTSVLPSFLKAMTCPNAVVSYEIVLSITRLIKKYGKELQAVTWDILLDIMERLLQQLQSLESQELKSIVHDLLTTVEELCDQNEFHGSEERFFELVERCADQRPESSVLNLIAYRAQSIHPAKDGWIHNLQMLMERFFRNESRSAVRIKVLDVLSFVLSINRQFYEEELINLVVISQLAHIPEDKDHQVRKLATQLLVDLAEGCNTHHFNSLLDIIEKVAAHSLSSPSELEERDLLSYSASLEDVKTAVLGLLIILQTKLYSLPSSHAMRVYEMLIHHIQRHYMYAYSLAVASSIRLQVFDFLLMLRADSLHRLGLSNKDGAVRFSPYCLCDFVEAEKRASEKKPTGTLSPPSGSPSVPSQNSTIRIGHLPYSMVFGVLLQCLKQETDWKVLKLVLNKLPESLRYKVLFLTSPCNIDLLASALSYMLTDKKTTDRLHGTPEGFSRTDLHLAVVPVLTALISYHNYLDKAKQREIVYCLEHGLIYRCANQCVVALSVCSVEMPDIIIKALPVLIVKLTHISATANMAIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSSLRLAKNAKQGLNNSPPVKELKEPSAVDAFRSRSISVSEHVVRSRIQTSITSSSLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTITTSVGTGTRSLLGLDSGDLQSSTESGSDPVLQVRQTKEAPAKLESQAGQQVCRSSRNRVRSMSGGHALRVGALDSTASHFPGGSASQGTQSPPAPAPRSEKTNPAPQTPLQKEKANLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRETALYKSLSVPSSSLATGTAKPSLLQRSNTVASFSSMYQSSCQGKLHRSISWAESAVVLEEGSPLEMELKETESPAESPESEDFETSCSEQVLSEERFGKAQEFYSRSSSTSSQDEKSLKSDELVEGGIPIGRVLPAEDGRALEELSFQPSQPLSKSSSSPELQTLQEILKDANGREVTRRLSTEVKSKSQSGNLEGEGLGSWLNKGEDARAAGSGGLDGSGPTTSPRSPSGHRPRGYTISDSAPSRRGKRMERDAFKSRTAATNAEKVPGINPSFVFLQLYHSPFFGDENNKPLLLPNETFEKSVQLLDQIPSYDTHKIAVLYVGEGQSNNEIAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKIYLGGLDVCGEDGQFTYCWHDDIMQAIFHIATLMPTKDLDKYRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYDCNLVTLQCRKDMEGLVDTSVAKIISDKNLPFVARQMALHANMASQVHHSRSNPTDTYPSKWIARLRHIKRLRHRLREETQYQTPGLPLQMHPSAPTKPSPQMAQDPPPAYETGQRKRLISSVDDFTEFV", "length": 1833, "header": "tr|A0A3Q2TYJ2-1|A0A3Q2TYJ2_CHICK Isoform 1 of TSC complex subunit 2 OS=Gallus gallus OX=9031 GN=TSC2 PE=1 SV=1 CANONICAL=A0A3Q2TYJ2-1" }, "isoforms": [ { "isoform_ac": "A0A1D5PM46-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYJ2/entry#A0A1D5PM46-1", "sequence": { "sequence": "MAKPQSKDSGLKEKFKNLLGLGTSRGSSKSSEGKQTEFIITAEILKELSIECGLSNRIRAISQICEVAKTKKIEEHAVEAIWKVVADMLQPERPAEARHAVLHLLKSIIQGQGERLGILRAHFFKVIKDYPSNEDLHERLEVFKALTENGRYITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLEDYVADMVHKICILCIQTSSSVDIEISLQVLDAVVCYNCLPSENLPVFIITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMADAALLRGAVFFVGMALWGAHRLNSLKNSPTSVLPSFLKAMTCPNAVVSYEIVLSITRLIKKYGKELQAVTWDILLDIMERLLQQLQSLESQELKSIVHDLLTTVEELCDQNEFHGSEERFFELVERCADQRPESSVLNLIAYRAQSIHPAKDGWIHNLQMLMERFFRNESRSAVRIKVLDVLSFVLSINRQFYEEELINLVVISQLAHIPEDKDHQVRKLATQLLVDLAEGCNTHHFNSLLDIIEKVAAHSLSSPSELEERDLLSYSASLEDVKTAVLGLLIILQTKLYSLPSSHAMRVYEMLIHHIQRHYMYAYSLAVASSIRLQVFDFLLMLRADSLHRLGLSNKDGAVRFSPYCLCDFVEAEKRASEKKPTGTLSPPSGSPSVPSQNSTIRIGHLPYSMVFGVLLQCLKQETDWKVLKLVLNKLPESLRYKVLFLTSPCNIDLLASALSYMLTDKKTTDRLHGTPEGFSRTDLHLAVVPVLTALISYHNYLDKAKQREIVYCLEHGLIYRCANQCVVALSVCSVEMPDIIIKALPVLIVKLTHISATANMAIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSSLRLAKNAKQGLNNSPPVKELKEPSAVDAFRSRSISVSEHVVRSRIQTSITSSSLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTITTSVGTGTRSLLGLDSGDLQSSTESGSDPVLQVRQTKEAPAKLESQAGQQVCRSSRNRVRSMSGGHALRVGALDSTASHFPGGSASQGTQSPPAPAPRSEKTNPAPQTPLQKEKANLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRETALYKSLSVPSSSLATGTAKPSLLQRSNTESAVVLEEGSPLEMELKETESPAESPESEDFETSCSEQVLSEERFGKAQEFYSRSSSTSSQDEKSLKSDELVEGGIPIGRVLPAEDGRALEELSFQPSQPLSKSSSSPELQTLQEILKDANGREVTRRLSTEVKSKSQSGNLEGEGLGSWLNKGEDARAAGSGGLDGSGPTTSPRSPSGHRPRGYTISDSAPSRRGKRMERDAFKSRTAATNAEKVPGINPSFVFLQLYHSPFFGDENNKPLLLPNETFEKSVQLLDQIPSYDTHKIAVLYVGEGQSNNEIAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKIYLGGLDVCGEDGQFTYCWHDDIMQAIFHIATLMPTKDLDKYRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYDCNLVTLQCRKDMEGLVDTSVAKIISDKNLPFVARQMALHANMASQVHHSRSNPTDTYPSKWIARLRHIKRLRHRLREETQYQTPGLPLQMHPSAPTKPSPQMAQDPPPAYETGQRKRLISSVDDFTEFV", "length": 1810, "header": "tr|A0A1D5PM46-1|A0A1D5PM46_CHICK Computationally mapped isoform of TSC complex subunit 2 OS=Gallus gallus OX=9031 GN=TSC2 PE=1 SV=1 CANONICAL=A0A3Q2TYJ2-1" }, "locus": { "chromosome": "14", "start_pos": 6301583, "end_pos": 6273082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043364.1", "url": "https://www.ensembl.org/id/ENSGALT00010043364.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025773.1", "url": "https://www.ensembl.org/id/ENSGALP00010025773.1" } ] } }, { "isoform_ac": "A0A3Q2TYJ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYJ2/entry#A0A3Q2TYJ2-1", "sequence": { "sequence": "MAKPQSKDSGLKEKFKNLLGLGTSRGSSKSSEGKQTEFIITAEILKELSIECGLSNRIRAISQICEVAKTKKIEEHAVEAIWKVVADMLQPERPAEARHAVLHLLKSIIQGQGERLGILRAHFFKVIKDYPSNEDLHERLEVFKALTENGRYITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLEDYVADMVHKICILCIQTSSSVDIEISLQVLDAVVCYNCLPSENLPVFIITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMADAALLRGAVFFVGMALWGAHRLNSLKNSPTSVLPSFLKAMTCPNAVVSYEIVLSITRLIKKYGKELQAVTWDILLDIMERLLQQLQSLESQELKSIVHDLLTTVEELCDQNEFHGSEERFFELVERCADQRPESSVLNLIAYRAQSIHPAKDGWIHNLQMLMERFFRNESRSAVRIKVLDVLSFVLSINRQFYEEELINLVVISQLAHIPEDKDHQVRKLATQLLVDLAEGCNTHHFNSLLDIIEKVAAHSLSSPSELEERDLLSYSASLEDVKTAVLGLLIILQTKLYSLPSSHAMRVYEMLIHHIQRHYMYAYSLAVASSIRLQVFDFLLMLRADSLHRLGLSNKDGAVRFSPYCLCDFVEAEKRASEKKPTGTLSPPSGSPSVPSQNSTIRIGHLPYSMVFGVLLQCLKQETDWKVLKLVLNKLPESLRYKVLFLTSPCNIDLLASALSYMLTDKKTTDRLHGTPEGFSRTDLHLAVVPVLTALISYHNYLDKAKQREIVYCLEHGLIYRCANQCVVALSVCSVEMPDIIIKALPVLIVKLTHISATANMAIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSSLRLAKNAKQGLNNSPPVKELKEPSAVDAFRSRSISVSEHVVRSRIQTSITSSSLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTITTSVGTGTRSLLGLDSGDLQSSTESGSDPVLQVRQTKEAPAKLESQAGQQVCRSSRNRVRSMSGGHALRVGALDSTASHFPGGSASQGTQSPPAPAPRSEKTNPAPQTPLQKEKANLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRETALYKSLSVPSSSLATGTAKPSLLQRSNTVASFSSMYQSSCQGKLHRSISWAESAVVLEEGSPLEMELKETESPAESPESEDFETSCSEQVLSEERFGKAQEFYSRSSSTSSQDEKSLKSDELVEGGIPIGRVLPAEDGRALEELSFQPSQPLSKSSSSPELQTLQEILKDANGREVTRRLSTEVKSKSQSGNLEGEGLGSWLNKGEDARAAGSGGLDGSGPTTSPRSPSGHRPRGYTISDSAPSRRGKRMERDAFKSRTAATNAEKVPGINPSFVFLQLYHSPFFGDENNKPLLLPNETFEKSVQLLDQIPSYDTHKIAVLYVGEGQSNNEIAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKIYLGGLDVCGEDGQFTYCWHDDIMQAIFHIATLMPTKDLDKYRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYDCNLVTLQCRKDMEGLVDTSVAKIISDKNLPFVARQMALHANMASQVHHSRSNPTDTYPSKWIARLRHIKRLRHRLREETQYQTPGLPLQMHPSAPTKPSPQMAQDPPPAYETGQRKRLISSVDDFTEFV", "length": 1833, "header": "tr|A0A3Q2TYJ2-1|A0A3Q2TYJ2_CHICK Isoform 1 of TSC complex subunit 2 OS=Gallus gallus OX=9031 GN=TSC2 PE=1 SV=1 CANONICAL=A0A3Q2TYJ2-1" }, "locus": { "chromosome": "14", "start_pos": 6301583, "end_pos": 6273082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043351.1", "url": "https://www.ensembl.org/id/ENSGALT00010043351.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025766.1", "url": "https://www.ensembl.org/id/ENSGALP00010025766.1" } ] } }, { "isoform_ac": "A0A8V0Z5G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A3Q2TYJ2/entry#A0A8V0Z5G1-1", "sequence": { "sequence": "MAKPQSKDSGLKEKFKNLLGLGTSRGSSKSSEGKQTEFIITAEILKELSIECGLSNRIRAISQICEVAKTKKIEEHAVEAIWKVVADMLQPERPAEARHAVLHLLKSIIQGQGERLGILRAHFFKVIKDYPSNEDLHERLEVFKALTENGRYITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLEDYVADMVHKICILCIQTSSSVDIEISLQVLDAVVCYNCLPSENLPVFIITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRAYMADAALLRGAVFFVGMALWGAHRLNSLKNSPTSVLPSFLKAMTCPNAVVSYEIVLSITRLIKKYGKELQAVTWDILLDIMERLLQQLQSLESQELKSIVHDLLTTVEELCDQNEFHGSEERFFELVERCADQRPESSVLNLIAYRAQSIHPAKDGWIHNLQMLMERFFRNESRSAVRIKVLDVLSFVLSINRQFYEEELINLVVISQLAHIPEDKDHQVRKLATQLLVDLAEGCNTHHFNSLLDIIEKVAAHSLSSPSELEERDLLSYSASLEDVKTAVLGLLIILQTKLYSLPSSHAMRVYEMLIHHIQRHYMYAYSLAVASSIRLQVFDFLLMLRADSLHRLGLSNKDGAVRFSPYCLCDFVEAEKRASEKKPTGTLSPPSGSPSVPSQNSTIRIGHLPYSMVFGVLLQCLKQETDWKVLKLVLNKLPESLRYKVLFLTSPCNIDLLASALSYMLTDKKTTDRLHGTPEGFSRTDLHLAVVPVLTALISYHNYLDKAKQREIVYCLEHGLIYRCANQCVVALSVCSVEMPDIIIKALPVLIVKLTHISATANMAIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSITSSSLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTITTSVGTGTRSLLGLDSGDLQSSTESGSDPVLQVRQTKEAPAKLESQAGQQVCRSSRNRVRSMSGGHALRVGALDSTASHFPGGSASQGTQSPPAPAPRSEKTNPAPQTPLQKEKANLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRETALYKSLSVPSSSLATGTAKPSLLQRSNTVASFSSMYQSSCQGKLHRSISWAESAVVLEEGSPLEMELKETESPAESPESEDFETSCSEQVLSEERFGKAQEFYSRSSSTSSQDEKSLKSDELVEGGIPIGRVLPAEDGRALEELSFQPSQPLSKSSSSPELQTLQEILKDANGREVTRRLSTEVKSKSQSGNLEGEGLGSWLNKGEDARAAGSGGLDGSGPTTSPRSPSGHRPRGYTISDSAPSRRGKRMERDAFKSRTAATNAEKVPGINPSFVFLQLYHSPFFGDENNKPLLLPNETFEKSVQLLDQIPSYDTHKIAVLYVGEGQSNNEIAILSNEHGSYRYTEFLTGLGKLIELKDCQPDKIYLGGLDVCGEDGQFTYCWHDDIMQAIFHIATLMPTKDLDKYRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIITPLDYDCNLVTLQCRKDMEGLVDTSVAKIISDKNLPFVARQMALHANMASQVHHSRSNPTDTYPSKWIARLRHIKRLRHRLREETQYQTPGLPLQMHPSAPTKPSPQMAQDPPPAYETGQRKRLISSVDDFTEFV", "length": 1789, "header": "tr|A0A8V0Z5G1-1|A0A3Q2TYJ2_CHICK Computationally mapped isoform of TSC complex subunit 2 OS=Gallus gallus OX=9031 GN=TSC2 PE=1 SV=1 CANONICAL=A0A3Q2TYJ2-1" }, "locus": { "chromosome": "14", "start_pos": 6301583, "end_pos": 6273082, "strand": "-", "evidence": [ { "database": "Ensembl Transcript", "id": "ENSGALT00010043371.1", "url": "https://www.ensembl.org/id/ENSGALT00010043371.1" }, { "database": "Ensembl Peptide", "id": "ENSGALP00010025777.1", "url": "https://www.ensembl.org/id/ENSGALP00010025777.1" } ] } } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "gga:416552", "name": "", "url": "https://www.genome.jp/dbget-bin/get_linkdb?-t+pathway+gga:416552", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P49815-1", "protein_name": "Tuberin", "gene_name": "TSC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKPTSKDSGLKEKFKILLGLGTPRPNPRSAEGKQTEFIITAEILRELSMECGLNNRIRMIGQICEVAKTKKFEEHAVEALWKAVADLLQPERPLEARHAVLALLKAIVQGQGERLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELADFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIARMVQMICLLCVRTASSVDIEVSLQVLDAVVCYNCLPAESLPLFIVTLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCHLMEDRAYMEDAPLLRGAVFFVGMALWGAHRLYSLRNSPTSVLPSFYQAMACPNEVVSYEIVLSITRLIKKYRKELQVVAWDILLNIIERLLQQLQTLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYFELVERCADQRPESSLLNLISYRAQSIHPAKDGWIQNLQALMERFFRSESRGAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDVAAYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYEMLVSHIQLHYKHSYTLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCVCDYMEPERGSEKKTSGPLSPPTGPPGPAPAGPAVRLGSVPYSLLFRVLLQCLKQESDWKVLKLVLGRLPESLRYKVLIFTSPCSVDQLCSALCSMLSGPKTLERLRGAPEGFSRTDLHLAVVPVLTALISYHNYLDKTKQREMVYCLEQGLIHRCASQCVVALSICSVEMPDIIIKALPVLVVKLTHISATASMAVPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPFITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARPPKQGLNNSPPVKEFKESSAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSVAQADDSLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGELQSGPESSSSPGVHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGALDVPASQFLGSATSPGPRTAPAAKPEKASAGTRVPVQEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAASTAKPPPLPRSNTVASFSSLYQSSCQGQLHRSVSWADSAVVMEEGSPGEVPVLVEPPGLEDVEAALGMDRRTDAYSRSSSVSSQEEKSLHAEELVGRGIPIERVVSSEGGRPSVDLSFQPSQPLSKSSSSPELQTLQDILGDPGDKADVGRLSPEVKARSQSGTLDGESAAWSASGEDSRGQPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDALKSRATASNAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESQSFERSVQLLDQIPSYDTHKIAVLYVGEGQSNSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIVYNDSGEDFKLGTIKGQFNFVHVIVTPLDYECNLVSLQCRKDMEGLVDTSVAKIVSDRNLPFVARQMALHANMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRICEEAAYSNPSLPLVHPPSHSKAPAQTPAEPTPGYEVGQRKRLISSVEDFTEFV", "length": 1807 }, "evidence": [ { "id": "A0A3Q2TYJ2", "url": "https://omabrowser.org/oma/group/A0A3Q2TYJ2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49816-1", "protein_name": "Tuberin", "gene_name": "Tsc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKPTSKDSGLKEKFKILLGLGTSRPNPRCAEGKQTEFIITAEILRELSGECGLNNRIRMIGQICDVAKTKKLEEHAVEALWKAVSDLLQPERPPEARHAVLALLKAIVQGQGDRLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIAPMVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFIITLCRTVNVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMENRSYMEDAPLLRGAVFFVGMALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDILLDIIERLLQQLQNLDSPELRTIVHDLLTTVEELCDQNEFHGSQERYYELVESYADQRPESSLLNLITYRAQSIHPAKDGWIQNLQLLMERFFRNECRSAVRIKVLDVLSFVLLINRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPLELEERDLAVYSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYETLISHIQLHYKHGYSLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCLCDCAELDRASEKKASGPLSPPTGPPSPVPTGPAVRLGHLPYSLLFRVLLQCLKQETDWKVLKLVLSKLPESLRYKVLIFTSPCSVDQLSSALCSMLSAPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMAIPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDKFRARSTSLNERPKSLRIARAPKQGLNNSPPVKEFKESCAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGDLQGGSASSSDPGTHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGVLDTSAPYTPGGPASLGAQAAPAARPEKPCAGAQLPAAEKANLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHRDTALYKSLSVPAAGTAKPPTLPRSNTVASFSSLYQPSCQGQLHRSVSWADSAVVLEEGSPGEAHVPVEPPELEDFEAALGTDRHCQRPDAYSRSSSASSQEEKSHLEELAAGGIPIERAISSEGARPTVDLSFQPSQPLSKSSSSPELQTLQDILGDLGDKTDIGRLSPEAKVRSQSGILDGEAATWSAPGEESRITVPPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDNFKSRTAASSAEKVPGINPSFVFLQLYHSPFCGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIIYNDSGEDFKLGTIKGQFNFVHVIITPLDYKCNLLTLQCRKDMEGLVDTSVAKIVSDRNLSFVARQMALHANMASQVHHRRSNPTDIYPSKWIARLRHIKRLRQRIREEVHYSNPSLPLMHPPAHTKVPAQAPTEATPTYETGQRKRLISSVDDFTEFV", "length": 1809 }, "evidence": [ { "id": "A0A3Q2TYJ2", "url": "https://omabrowser.org/oma/group/A0A3Q2TYJ2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q61037-1", "protein_name": "Tuberin", "gene_name": "Tsc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKPTSKDSGLKEKFKILLGLGTSRPNPRCAEGKQTEFIITSEILRELSGECGLNNRIRMIGQICDVAKTKKLEEHAVEALWKAVSDLLQPERPPEARHAVLTLLKAIVQGQGDRLGVLRALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVLVNLVKFNSCYLDEYIASMVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFIITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRSYMEDAPLLRGAVFFVGMALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDILLDIIERLLQQLQNLDSPELKTIVHDLLTTVEELCDQNEFHGSQERYYELVESYADQRPESSLLNLISYRAQSIHPAKDGWIQNLQLLMERFFRNECRSAVAIKVLDVLSFVLLIIRQFYEEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLSPPPELEERDLAVHSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYESLISHIQLHYKHGYSLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCLCDCMELDRASEKKASGPLSPPTGPPSPVPMGPAVRLGYLPYSLLFRVLLQCLKQESDWKVLKLVLSRLPESLRYKVLIFTSPCSVDQLSSALCSMLSAPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYLDKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMAIPLLEFLSTLARLPHLYRNFVPEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRCRLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSLRIARAPKQGLNNSPPVKEFKESCAAEAFRCRSISVSEHVVRSRIQTSLTSASLGSADENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVGNKLVTVTTSVGTGTRSLLGLDSGDLQGGSDSSSDPSTHVRQTKEAPAKLESQAGQQVSRGARDRVRSMSGGHGLRVGVLDTSAPYSPGGSASLGPQTAVAAKPEKPPAGAQLPTAEKTNLAAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKEHGHAPVQVIVSATGCTAKPPTLPRSNTVASFSSLYQPSCQGQLHRSVSWADSAMVLEEGSPGETQVPVEPPELEDFEAALGTDRHCQRPDTYSRSSSASSQEEKSHLEELAAGGIPIERAISSEGARPAVDLSFQPSQPLSKSSSSPELQTLQDILGDLGDKIDIGRLSPEAKVRSQSGILDGEAATWSATGEESRITVPPEGPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDNFKSRAAASSAEKVPGINPSFVFLQLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAILSNEHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATLMPTKDVDKHRCDKKRHLGNDFVSIIYNDSGEDFKLGTIKQGQFNFVHVIITPLDYKCNLLTLQCRKDGPACKCEWWRQPGEIVVWALPVVMELTVTILLCHLQMASQVHHSRSNPTDIYPSKWIARLRHIKRLRQRIREEVHYSNPSLPLMHPPAHTKAPAQAPEATPTYETGQRKRLISSVDDFTEFV", "length": 1814 }, "evidence": [ { "id": "A0A3Q2TYJ2", "url": "https://omabrowser.org/oma/group/A0A3Q2TYJ2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VW83-1", "protein_name": "Gigas, isoform A", "gene_name": "gig", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNSKDKSKFKLFLKSLPAGYVGERTLRPEFERELRPEQPVAQRCRMLKELGDTQLHNFNLDESAITILFNLTNDLIVPNKPAETRQIALSFYKRLIHTQYKNLTIMREKFFLVIQNHEAREDLRHLLELLDTLTDNGKDITNFEEKIGKFMLLWIPAITEANLLTPYLDILVNLIKFNAAHLDKDILVGIVQNACDLSCSVTVNEIGLQCLTILEMVIGYTIFPSEPLPQCITTLCRTVNHAPYCPSSFKIMKNLLGTQLGYHSMKMMCSILNDRALYDDAHLLRGAVFHLNMNIFGSNIIFQVSPMTYATNVLTAFLRALDSRQVIVTFEVILSVRMVITKRQLSEIIWDLICDIMSSIVSNIEYYEEVNINKDRLHHLQINFHENIDCIEKLLQQDRSQILGNVERIYDLIERVADRRPEASVLALIEYRSRRVTATRPDWLQVLAQFVRRYYRMSNVNVRIKTIEALVQIMDQNRACYEEEILSRVVLVHLSHIHLESSVQVRVAVARALSNFATHCDTKRCMDLLDILEALINRPFEHTRHGSSSGEGTLAEVTFGLVNNESEISDIIAAVDGLVKVFAIKLHRLPGIHALKIFNILMDHLELHYERPKIFEHISVVRYKIFAWLLKARANGSYHIGYPEGSTEVVKFSPYLGIDSPLLPQAHPTAISIRRVCKLIVRCLEHDTDYQVFQLVIRELPKVLQNKALVQGNDIEELANTLLKINLVSNNKFKRPTDEFHALVLPAIASLVIYHESLQPQQHYGIITALNSRVLTGIASVCINTMTILILEMPEALMRKLPDVLLQMSKMSDTNALATPVLEFLSLLIHLSKHLFANFTSMHNMYVFAITLPYTKPHRYDHYTVSLAHHVIAGWFLKCKLELRRNCVNYIKSSIQSNAKMLSSDIVNLNSLNEDSSNRKRSTSLTERGSRNNANAWNDLEMRPQMNNGLRNFHAELAETCFDFLARHTYSPCPSMPKRLPAAEFLLKDGVSQTWLVGNNLVTITTSGCPSAPARSGLCERCAQLGKAPSISLNSKSLSDAAPPLSPERERRYTKVSLQHSSGNESAGSTELTSSSSSNSAAAGGHPHRQISNSSTASLDALSRRGSNPEALGSALGEGAHTGSNTSLLGNSLSQSSVSMSPSSGSVVQQPVCVRACTGWAEVLVRRPTGNVSWITRIQNPITNDCFGQELPFNNVVSLFLPTAHGGVFGPDNTIQAPPHTLADPEPEPEAEVNAATAPQASALRSRMVAKARALQRQEEIHSVGGNGNGNGNGNGSGNAPSTGGAAAIPIPRVPASGKRGKEAALCGSVSDGEADDDSLAFEDAQSRARNPVRRVNSSPEMSSSWRQSFLTNKPTPLSQEPVKTTADEPQSLLTLKKKTVQYSTKDMRVSCEAIPEEIAGSTPPSQAAALALQPESGTLPPKQHSADDVSSHVAGGSNLQAGGSTLKLGKPPLSPGQPPLLGTGRVTSFGGTSVPQPGALAKSSSSGSNGTNVGVITSDYDNGNNGNGDMMRGRSKTISVVREVNNGNTRPPPASSFRNFGAAKPPINTKLCMNPSFIFMQLYTTGQLGVTDEPLKVGPENSSAVSLIDLVPPFETHKIGVLYVGQGQCNNEVEILRNSHGSARYVEFLRNIGTLVSLKEAEQNNLFIMLDRNGADGKFAYIWKDDILQVTFHVATLMPTNLQDDPNCNEKKSHIGNDFVKIIYNESGEEYNLNTISGQFNYACVIVEPLDLNSNRVYVKARSEISKFVCHAEYRIVSDRSAPLLARQMALHANLASLVYQSVQKKHPYASNWLERLRKLKRLRSKLIEGLNSQQKSGSASSGIGINASAIGSDMDDQRGDFIKYT", "length": 1847 }, "evidence": [ { "id": "A0A3Q2TYJ2", "url": "https://omabrowser.org/oma/group/A0A3Q2TYJ2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "TSC1-TSC2 complex", "id": "GO:0033596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033596", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "protein homodimerization activity", "id": "GO:0042803", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042803", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "Hsp90 protein binding", "id": "GO:0051879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051879", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "phosphatase binding", "id": "GO:0019902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019902", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "regulation of small GTPase mediated signal transduction", "id": "GO:0051056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051056", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "negative regulation of TOR signaling", "id": "GO:0032007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032007", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "positive regulation of macroautophagy", "id": "GO:0016239", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016239", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "cellular response to starvation", "id": "GO:0009267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009267", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "anoikis", "id": "GO:0043276", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043276", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" }, { "name": "negative regulation of TORC1 signaling", "id": "GO:1904262", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904262", "evidence": [ { "database": "UniProtKB", "id": "A0A3Q2TYJ2", "url": "https://www.uniprot.org/uniprot/A0A3Q2TYJ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1039, "end_pos": 1041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1210, "end_pos": 1212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1549, "end_pos": 1551, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1676, "end_pos": 1678, 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