{ "uniprot_canonical_ac": "A0A287ASR6-1", "uniprot_ac": "A0A287ASR6", "uniprot_id": "A0A287ASR6_PIG", "mass": { "chemical_mass": 85926.0, "monoisotopic_mass": 85926.0 }, "refseq": {}, "gene_names": [ { "name": "ADAM33", "resource": "UniProtKB", "type": "recommended", "url": "https://www.uniprot.org/uniprot/A0A287ASR6", "id": "A0A287ASR6" } ], "protein_names": [ { "name": "ADAM metallopeptidase domain 33", "resource": "UniProtKB", "type": "synonym", "url": "https://www.uniprot.org/uniprotkb/A0A287ASR6/entry#names_and_taxonomy", "id": "A0A287ASR6" } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Sus scrofa", "taxid": 9823, "evidence": [ { "database": "UniProtKB", "id": "A0A287ASR6", "url": "https://www.uniprot.org/uniprot/A0A287ASR6" } ], "common_name": "Pig", "glygen_name": "Pig", "reference_species": "Sus scrofa [9823]" } ], "gene": [ { "name": "ADAM33", "url": "https://www.uniprot.org/uniprot/A0A287ASR6", "locus": { "chromosome": "17", "start_pos": 32037880, "end_pos": 32023091, "strand": "-", "evidence": [ { "database": "Ensembl Gene", "id": "ENSSSCG00000007145", "url": "https://www.ensembl.org/id/ENSSSCG00000007145" } ] } } ], "crossref": [ { "id": "ENSSSCG00000007145", "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000007145", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034027", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034027", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11905:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11905:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00200", "url": "http://pfam.xfam.org/family/PF00200", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01421", "url": "http://pfam.xfam.org/family/PF01421", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF01562", "url": "http://pfam.xfam.org/family/PF01562", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "PF08516", "url": "http://pfam.xfam.org/family/PF08516", "database": "Pfam", "categories": [ "Protein Classification" ] }, { "id": "R-SSC-9762292", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9762292", "database": "Reactome", "categories": [ "Protein Classification" ] }, { "id": "A0A287ASR6", "url": "https://www.uniprot.org/uniprot/A0A287ASR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287ASR6-1", "url": "https://www.uniprot.org/uniprot/A0A287ASR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B740", "url": "https://www.uniprot.org/uniprot/A0A287B740", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A287B740-1", "url": "https://www.uniprot.org/uniprot/A0A287B740-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGRGYRRTSGSPALGLLLLLRLPWQVWGAEAFRGNTAGEPVIPHWVLDGRPRHMVTLEEQVSKLEVGLVALKAEGQGLLLELEKNHRLLAPGYTETHYGPDRQPVVLVPNHTDHCHYHGRVRGFPDSWVVLSTCSGMRGLIVLSNNASYYMHPWSAEDSKDFWTHKIFWMERLLSWKGACGHRDPGDKRDMPSLSQATRIRERRESPWSPRYLELYLVADHTLFLTQHRNLNHTKQRLLEVANYVDQILRTLDIQVALTGLEVWTEQDRSRVTSDANATLWAFLQWRRELWARRPHDSAQLLTGRAFQGATVGLAPVEGMCHAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHDRNGCCVEATAEQGGCVMAAATGQPFPRVFSACSRRQLRAYFRKGGGACLSNAPDSGLLVPRARCGNGFVEEGEECDCGTGQECLDSCCLAHNCSLRAGAQCTHGDCCAYCLLKPAGALCRRAVGDCDLPEFCTGTSPYCPPDIYLLDGSPCASGRGYCRDGACPTLEQQCRQLWGPGSRPAPEACFQVVNSAGDAHGNCGQRGDGSFVPCAQRDAQCGKLQCQGGEQSALVPHTAPVDSTVHLGSRELTCRGAFVLPGAQLDLPDLGLVESGTQCGPRMVCQERRCQNTTFQELELCLAACHGHGVCNSNRNCHCSPGWAPPSCDKPGFGGSVDSGPVQPESQDTFTLAVILSFLLPLLPGAGLAWCCFQHPGLHLQQCLWGSRRDPMSSRSRHSSCRDCPLGSVHPMELGLTTTGEPRPLDLENSAGTQEPP", "length": 790, "header": "tr|A0A287ASR6-1|A0A287ASR6_PIG Isoform 1 of ADAM metallopeptidase domain 33 OS=Sus scrofa OX=9823 GN=ADAM33 PE=4 SV=1 CANONICAL=A0A287ASR6-1" }, "isoforms": [ { "isoform_ac": "A0A287ASR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASR6/entry#A0A287ASR6-1", "sequence": { "sequence": "MGRGYRRTSGSPALGLLLLLRLPWQVWGAEAFRGNTAGEPVIPHWVLDGRPRHMVTLEEQVSKLEVGLVALKAEGQGLLLELEKNHRLLAPGYTETHYGPDRQPVVLVPNHTDHCHYHGRVRGFPDSWVVLSTCSGMRGLIVLSNNASYYMHPWSAEDSKDFWTHKIFWMERLLSWKGACGHRDPGDKRDMPSLSQATRIRERRESPWSPRYLELYLVADHTLFLTQHRNLNHTKQRLLEVANYVDQILRTLDIQVALTGLEVWTEQDRSRVTSDANATLWAFLQWRRELWARRPHDSAQLLTGRAFQGATVGLAPVEGMCHAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHDRNGCCVEATAEQGGCVMAAATGQPFPRVFSACSRRQLRAYFRKGGGACLSNAPDSGLLVPRARCGNGFVEEGEECDCGTGQECLDSCCLAHNCSLRAGAQCTHGDCCAYCLLKPAGALCRRAVGDCDLPEFCTGTSPYCPPDIYLLDGSPCASGRGYCRDGACPTLEQQCRQLWGPGSRPAPEACFQVVNSAGDAHGNCGQRGDGSFVPCAQRDAQCGKLQCQGGEQSALVPHTAPVDSTVHLGSRELTCRGAFVLPGAQLDLPDLGLVESGTQCGPRMVCQERRCQNTTFQELELCLAACHGHGVCNSNRNCHCSPGWAPPSCDKPGFGGSVDSGPVQPESQDTFTLAVILSFLLPLLPGAGLAWCCFQHPGLHLQQCLWGSRRDPMSSRSRHSSCRDCPLGSVHPMELGLTTTGEPRPLDLENSAGTQEPP", "length": 790, "header": "tr|A0A287ASR6-1|A0A287ASR6_PIG Isoform 1 of ADAM metallopeptidase domain 33 OS=Sus scrofa OX=9823 GN=ADAM33 PE=4 SV=1 CANONICAL=A0A287ASR6-1" }, "locus": {} }, { "isoform_ac": "A0A287B740-1", "url": "https://www.uniprot.org/uniprotkb/A0A287ASR6/entry#A0A287B740-1", "sequence": { "sequence": "MGRGYRRTSGSPALGLLLLLRLPWQVWGAEAFRGNTAGEPVIPHWVLDGRPRHMVTLEEQVSKLEVGLVALKAEGQGLLLELEKNHRLLAPGYTETHYGPDRQPVVLVPNHTDHCHYHGRVRGFPDSWVVLSTCSGMRGLIVLSNNASYYMHPWSAEDSKDFWTHKIFWMERLLSWKGACGHRDPGDKRDMPSLSQATRIRFLTQHRNLNHTKQRLLEVANYVDQILRTLDIQVALTGLEVWTEQDRSRVTSDANATLWAFLQWRRELWARRPHDSAQLLTGRAFQGATVGLAPVEGMCHAESSGGVSTDHSELPIGAAATMAHEIGHSLGLSHDRNGCCVEATAEQGGCVMAAATGQPFPRVFSACSRRQLRAYFRKGGGACLSNAPDSGLLVPRARCGNGFVEEGEECDCGTGQECLDSCCLAHNCSLRAGAQCTHGDCCAYCLLKPAGALCRRAVGDCDLPEFCTGTSPYCPPDIYLLDGSPCASGRGYCRDGACPTLEQQCRQLWGPGSRPAPEACFQVVNSAGDAHGNCGQRGDGSFVPCAQRDAQCGKLQCQGGEQSALVPHTAPVDSTVHLGSRELTCRGAFVLPGAQLDLPDLGLVESGTQCGPRMVCQERRCQNTTFQELELCLAACHGHGVCNSNRNCHCSPGWAPPSCDKPGFGGSVDSGPVQPESQDTFTLAVILSFLLPLLPGAGLAWCCFQHPGLHLQQCLWGSRRDPMSSRSRHSSCRDCPLGSVHPMELGLTTTGEPRPLDLENSAGTQEPP", "length": 768, "header": "tr|A0A287B740-1|A0A287ASR6_PIG Computationally mapped isoform of ADAM metallopeptidase domain 33 OS=Sus scrofa OX=9823 GN=ADAM33 PE=4 SV=1 CANONICAL=A0A287ASR6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-SSC-9762292", "name": "Regulation of CDH11 function", "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-9762292", "resource": "Reactome", "description": "Regulation of CDH11 function" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "A0A287ASR6", "url": "https://www.uniprot.org/uniprot/A0A287ASR6" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A287ASR6", "url": "https://www.uniprot.org/uniprot/A0A287ASR6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A287ASR6", "url": "https://www.uniprot.org/uniprot/A0A287ASR6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A287ASR6", "url": "https://www.uniprot.org/uniprot/A0A287ASR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 645, "end_pos": 647, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 277, "end_pos": 279 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 645, "end_pos": 647 } ] }, "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }