{
    "uniprot_canonical_ac": "A0A287AS32-1",
    "uniprot_ac": "A0A287AS32",
    "uniprot_id": "A0A287AS32_PIG",
    "mass": {
        "chemical_mass": 39675.0,
        "monoisotopic_mass": 39675.0
    },
    "refseq": {},
    "gene_names": [
        {
            "name": "WNT3",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprot/A0A287AS32",
            "id": "A0A287AS32"
        }
    ],
    "protein_names": [
        {
            "name": "Protein Wnt",
            "resource": "UniProtKB",
            "type": "recommended",
            "url": "https://www.uniprot.org/uniprotkb/A0A287AS32/entry#names_and_taxonomy",
            "id": "A0A287AS32"
        }
    ],
    "function": [
        {
            "annotation": "Ligand for members of the frizzled family of seven transmembrane receptors.",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A287AS32",
                    "url": "https://www.uniprot.org/uniprot/A0A287AS32#function"
                },
                {
                    "database": "UniProtKB",
                    "id": "RU003500",
                    "url": "https://www.uniprot.org/uniprot/RU003500#function"
                }
            ]
        }
    ],
    "disease": [],
    "snv": [],
    "mutagenesis": [],
    "expression_tissue": [],
    "expression_disease": [],
    "species": [
        {
            "name": "Sus scrofa",
            "taxid": 9823,
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A287AS32",
                    "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                }
            ],
            "common_name": "Pig",
            "glygen_name": "Pig",
            "reference_species": "Sus scrofa [9823]"
        }
    ],
    "gene": [
        {
            "name": "WNT3",
            "url": "https://www.uniprot.org/uniprot/A0A287AS32",
            "locus": {
                "chromosome": "12",
                "start_pos": 17628726,
                "end_pos": 17681026,
                "strand": "+",
                "evidence": [
                    {
                        "database": "Ensembl Gene",
                        "id": "ENSSSCG00000017317",
                        "url": "https://www.ensembl.org/id/ENSSSCG00000017317"
                    }
                ]
            }
        }
    ],
    "crossref": [
        {
            "id": "ENSSSCG00000017317",
            "url": "https://bgee.org/?page=gene&gene_id=ENSSSCG00000017317",
            "database": "Bgee",
            "categories": [
                "Gene Expression"
            ]
        },
        {
            "id": "cd19335",
            "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19335",
            "database": "CDD",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR005817",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR005817",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR009141",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR009141",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR018161",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR018161",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "IPR043158",
            "url": "https://www.ebi.ac.uk/interpro/entry/IPR043158",
            "database": "InterPro",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "WNCTTIE",
            "url": "https://omabrowser.org/oma/group/WNCTTIE/",
            "database": "OMA",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "2874082at2759",
            "url": "http://www.orthodb.org/?query=2874082at2759",
            "database": "OrthoDB",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12027",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PTHR12027:SF82",
            "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12027:SF82",
            "database": "PANTHER",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "PF00110",
            "url": "http://pfam.xfam.org/family/PF00110",
            "database": "Pfam",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-SSC-201681",
            "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201681",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "R-SSC-3238698",
            "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3238698",
            "database": "Reactome",
            "categories": [
                "Protein Classification"
            ]
        },
        {
            "id": "A0A287AS32",
            "url": "https://www.uniprot.org/uniprot/A0A287AS32",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        },
        {
            "id": "A0A287AS32-1",
            "url": "https://www.uniprot.org/uniprot/A0A287AS32-1",
            "database": "UniProtKB",
            "categories": [
                "Protein"
            ]
        }
    ],
    "sequence": {
        "sequence": "MEPHLLGLLLGLLLCGTRVLAGYPIWWSLALGQQYTSLGSQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIRIYDVHTCK",
        "length": 355,
        "header": "tr|A0A287AS32-1|A0A287AS32_PIG Isoform 1 of Protein Wnt  OS=Sus scrofa OX=9823 GN=WNT3 PE=3 SV=3 CANONICAL=A0A287AS32-1"
    },
    "isoforms": [
        {
            "isoform_ac": "A0A287AS32-1",
            "url": "https://www.uniprot.org/uniprotkb/A0A287AS32/entry#A0A287AS32-1",
            "sequence": {
                "sequence": "MEPHLLGLLLGLLLCGTRVLAGYPIWWSLALGQQYTSLGSQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIRIYDVHTCK",
                "length": 355,
                "header": "tr|A0A287AS32-1|A0A287AS32_PIG Isoform 1 of Protein Wnt  OS=Sus scrofa OX=9823 GN=WNT3 PE=3 SV=3 CANONICAL=A0A287AS32-1"
            },
            "locus": {}
        }
    ],
    "glycosylation": [],
    "phosphorylation": [],
    "glycation": [],
    "keywords": [],
    "publication": [
        {
            "title": "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.",
            "journal": "PeerJ",
            "date": "2019",
            "authors": "Gilbert Donald G",
            "evidence": [
                {
                    "database": "UniProtKB",
                    "id": "A0A287AS32",
                    "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "30723633",
                    "url": "https://glygen.org/publication/PubMed/30723633"
                }
            ]
        }
    ],
    "pathway": [
        {
            "id": "R-SSC-201681",
            "name": "TCF dependent signaling in response to WNT",
            "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-201681",
            "resource": "Reactome",
            "description": "TCF dependent signaling in response to WNT"
        },
        {
            "id": "R-SSC-3238698",
            "name": "WNT ligand biogenesis and trafficking",
            "url": "https://www.reactome.org/PathwayBrowser/#R-SSC-3238698",
            "resource": "Reactome",
            "description": "WNT ligand biogenesis and trafficking"
        }
    ],
    "orthologs": [
        {
            "uniprot_canonical_ac": "A1DYI3-1",
            "protein_name": "Protein Wnt",
            "gene_name": "Wnt3",
            "tax_id": 9031,
            "organism": "Gallus gallus",
            "sequence": {
                "sequence": "MDYHLLGLILSFLFNGTKVLAGYPIWWSLALGQQYSSLGSQPILCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNRHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDYLKDKYDSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIRVYDVHTCK",
                "length": 355
            },
            "evidence": [
                {
                    "id": "A0A287AS32",
                    "url": "https://omabrowser.org/oma/group/A0A287AS32/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Chicken",
            "common_name": "Chicken"
        },
        {
            "uniprot_canonical_ac": "D3ZCR1-1",
            "protein_name": "Protein Wnt",
            "gene_name": "Wnt3",
            "tax_id": 10116,
            "organism": "Rattus norvegicus",
            "sequence": {
                "sequence": "MEPHLLGLLLGLLLSGTRVLAGYPIWWSLALGQQYTSLASQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCVFHWCCYVSCQECIRIYDVHTCK",
                "length": 355
            },
            "evidence": [
                {
                    "id": "A0A287AS32",
                    "url": "https://omabrowser.org/oma/group/A0A287AS32/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Rat",
            "common_name": "Rat"
        },
        {
            "uniprot_canonical_ac": "P17553-1",
            "protein_name": "Proto-oncogene Wnt-3",
            "gene_name": "Wnt3",
            "tax_id": 10090,
            "organism": "Mus musculus",
            "sequence": {
                "sequence": "MEPHLLGLLLGLLLSGTRVLAGYPIWWSLALGQQYTSLASQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCVFHWCCYVSCQECIRIYDVHTCK",
                "length": 355
            },
            "evidence": [
                {
                    "id": "A0A287AS32",
                    "url": "https://omabrowser.org/oma/group/A0A287AS32/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Mouse",
            "common_name": "Mouse"
        },
        {
            "uniprot_canonical_ac": "P56703-1",
            "protein_name": "Proto-oncogene Wnt-3",
            "gene_name": "WNT3",
            "tax_id": 9606,
            "organism": "Homo sapiens",
            "sequence": {
                "sequence": "MEPHLLGLLLGLLLGGTRVLAGYPIWWSLALGQQYTSLGSQPLLCGSIPGLVPKQLRFCRNYIEIMPSVAEGVKLGIQECQHQFRGRRWNCTTIDDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTSTICGCDSHHKGPPGEGWKWGGCSEDADFGVLVSREFADARENRPDARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRAKYSLFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVTSHGIDGCDLLCCGRGHNTRTEKRKEKCHCIFHWCCYVSCQECIRIYDVHTCK",
                "length": 355
            },
            "evidence": [
                {
                    "id": "A0A287AS32",
                    "url": "https://omabrowser.org/oma/group/A0A287AS32/",
                    "database": "OMA"
                }
            ],
            "glygen_name": "Human",
            "common_name": "Human"
        }
    ],
    "go_annotation": {
        "categories": [
            {
                "name": "Biological Process",
                "total": 25,
                "go_terms": [
                    {
                        "name": "head morphogenesis",
                        "id": "GO:0060323",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060323",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of gene expression",
                        "id": "GO:0010628",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010628",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "neuron differentiation",
                        "id": "GO:0030182",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "embryonic forelimb morphogenesis",
                        "id": "GO:0035115",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035115",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "canonical Wnt signaling pathway",
                        "id": "GO:0060070",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mesoderm formation",
                        "id": "GO:0001707",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001707",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "embryonic hindlimb morphogenesis",
                        "id": "GO:0035116",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035116",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of osteoblast differentiation",
                        "id": "GO:0045669",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045669",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "axon guidance",
                        "id": "GO:0007411",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "stem cell proliferation",
                        "id": "GO:0072089",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072089",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "limb bud formation",
                        "id": "GO:0060174",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060174",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "regulation of mesenchymal stem cell differentiation",
                        "id": "GO:2000739",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000739",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "anterior/posterior axis specification",
                        "id": "GO:0009948",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009948",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "gene expression",
                        "id": "GO:0010467",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010467",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "dorsal/ventral axis specification",
                        "id": "GO:0009950",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009950",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "positive regulation of Wnt signaling pathway",
                        "id": "GO:0030177",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030177",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "cell fate commitment",
                        "id": "GO:0045165",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045165",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "negative regulation of axon extension involved in axon guidance",
                        "id": "GO:0048843",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048843",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "gamete generation",
                        "id": "GO:0007276",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007276",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "midbrain dopaminergic neuron differentiation",
                        "id": "GO:1904948",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904948",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "mammary gland epithelium development",
                        "id": "GO:0061180",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061180",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "canonical Wnt signaling pathway involved in mesenchymal stem cell differentiation",
                        "id": "GO:0044338",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044338",
                        "evidence": [
                            {
                                "database": "UniProtKB",
                                "id": "A0A287AS32",
                                "url": "https://www.uniprot.org/uniprot/A0A287AS32"
                            }
                        ],
                        "pmid": ""
                    },
                    {
                        "name": "canonical Wnt signaling pathway involved in osteoblast differentiation",
                        "id": "GO:0044339",
                        "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044339",
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