{
    "glytoucan_ac": "G00659GQ",
    "number_monosaccharides": 4,
    "mass": 980.21,
    "mass_pme": 1162.41,
    "fully_determined": "yes",
    "iupac": "alpha-D-Neup5Ac-(2->3)-beta-D-Galp6S-(1->4)[alpha-L-Fucp-(1->3)]-beta-D-GlcpNAc6S-(1->",
    "wurcs": "WURCS=2.0/4,4,3/[a2122h-1b_1-5_2*NCC/3=O_6*OSO/3=O/3=O][a1221m-1a_1-5][a2112h-1b_1-5_6*OSO/3=O/3=O][Aad21122h-2a_2-6_5*NCC/3=O]/1-2-3-4/a3-b1_a4-c1_c3-d2",
    "glycoct": "RES 1b:b-dglc-HEX-1:5 2s:n-acetyl 3b:a-lgal-HEX-1:5|6:d 4b:b-dgal-HEX-1:5 5b:a-dgro-dgal-NON-2:6|1:a|2:keto|3:d 6s:n-acetyl 7s:sulfate 8s:sulfate LIN 1:1d(2+1)2n 2:1o(3+1)3d 3:1o(4+1)4d 4:4o(3+2)5d 5:5d(5+1)6n 6:4o(6+1)7n 7:1o(6+1)8n",
    "inchi": "InChI=1S/C31H52N2O29S2/c1-8-17(39)20(42)21(43)28(56-8)60-25-16(33-10(3)36)27(45)57-14(7-55-64(51,52)53)23(25)59-29-22(44)26(19(41)13(58-29)6-54-63(48,49)50)62-31(30(46)47)4-11(37)15(32-9(2)35)24(61-31)18(40)12(38)5-34/h8,11-29,34,37-45H,4-7H2,1-3H3,(H,32,35)(H,33,36)(H,46,47)(H,48,49,50)(H,51,52,53)/t8-,11-,12+,13+,14+,15+,16+,17+,18+,19-,20+,21-,22+,23+,24+,25+,26-,27+,28-,29-,31-/m0/s1",
    "glycam": "DNeup5Aca2-3DGalp[6S]b1-4[LFucpa1-3]DGlcpNAc[6S]b1-OH",
    "smiles_isomeric": "C[C@H]1[C@H]([C@H]([C@@H]([C@@H](O1)O[C@@H]2[C@H]([C@@H](O[C@@H]([C@H]2O[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COS(=O)(=O)O)O)O[C@@]4(C[C@@H]([C@H]([C@@H](O4)[C@@H]([C@@H](CO)O)O)NC(=O)C)O)C(=O)O)O)COS(=O)(=O)O)O)NC(=O)C)O)O)O",
    "inchi_key": {
        "key": "UXDHLDJFGXRXMU-UQTBNESHSA-N",
        "url": "https://pubchem.ncbi.nlm.nih.gov/compound/UXDHLDJFGXRXMU-UQTBNESHSA-N"
    },
    "crossref": [
        {
            "id": "G00659GQ",
            "database": "GlyTouCan",
            "url": "https://glytoucan.org/Structures/Glycans/G00659GQ",
            "categories": [
                "Glycan"
            ]
        },
        {
            "id": "GSD000008",
            "url": "https://wiki.glygen.org/Glycan_structure_dictionary#GSD000008",
            "database": "Glycan Structure Dictionary",
            "categories": [
                "Ontology and Dictionary"
            ]
        }
    ],
    "publication": [
        {
            "title": "Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X.",
            "journal": "The Journal of biological chemistry",
            "date": "1998",
            "authors": "Mitsuoka C, Sawada-Kasugai M, Ando-Furui K, Izawa M, Nakanishi H, Nakamura S, Ishida H, Kiso M, Kannagi R",
            "evidence": [
                {
                    "database": "Glycan Motif",
                    "id": "GGM.000028",
                    "url": "https://glycomotif.glyomics.org/glycomotif/GGM.000028"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "9556613",
                    "url": "https://glygen.org/publication/PubMed/9556613"
                }
            ]
        },
        {
            "title": "The repertoire of glycan determinants in the human glycome.",
            "journal": "Molecular bioSystems",
            "date": "2009",
            "authors": "Cummings RD",
            "evidence": [
                {
                    "database": "Glycan Motif",
                    "id": "GGM.000028",
                    "url": "https://glycomotif.glyomics.org/glycomotif/GGM.000028"
                }
            ],
            "reference": [
                {
                    "type": "PubMed",
                    "id": "19756298",
                    "url": "https://glygen.org/publication/PubMed/19756298"
                }
            ]
        }
    ],
    "residues": [],
    "composition": [
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 1,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 1,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 1,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 1,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 2,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        }
    ],
    "composition_expanded": [
        {
            "name": "Alditol",
            "residue": "aldi",
            "count": 0
        },
        {
            "name": "6-Deoxy-Hexose",
            "residue": "dhex",
            "count": 1,
            "cid": "840",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/840"
        },
        {
            "name": "6-Deoxy-Hexitol",
            "residue": "dhex+aldi",
            "count": 0
        },
        {
            "name": "L-Fucose",
            "residue": "fuc",
            "count": 1,
            "cid": "17106",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/17106"
        },
        {
            "name": "L-Fucitol",
            "residue": "fuc+aldi",
            "count": 0,
            "cid": "445724",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/445724"
        },
        {
            "name": "D-Galactose",
            "residue": "gal",
            "count": 1,
            "cid": "6036",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/6036"
        },
        {
            "name": "D-Galacitol",
            "residue": "gal+aldi",
            "count": 0,
            "cid": "11850",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/11850"
        },
        {
            "name": "N-Acetyl-D-galactosamine",
            "residue": "galnac",
            "count": 0,
            "cid": "35717",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/35717"
        },
        {
            "name": "N-Acetylgalactosaminitol",
            "residue": "galnac+aldi",
            "count": 0,
            "cid": "165880",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/165880"
        },
        {
            "name": "D-Galacturonic Acid",
            "residue": "gala",
            "count": 0,
            "cid": "439215",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439215"
        },
        {
            "name": "D-Glucose",
            "residue": "glc",
            "count": 0,
            "cid": "5793",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/5793"
        },
        {
            "name": "D-Glucitol",
            "residue": "glc+aldi",
            "count": 0,
            "cid": "5780",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/5780"
        },
        {
            "name": "D-Glucuronic acid",
            "residue": "glca",
            "count": 0,
            "cid": "94715",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/94715"
        },
        {
            "name": "D-Glucosamine",
            "residue": "glcn",
            "count": 0,
            "cid": "439213",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439213"
        },
        {
            "name": "N-Acetyl-D-Glucosamine",
            "residue": "glcnac",
            "count": 1,
            "cid": "439174",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439174"
        },
        {
            "name": "N-Acetyl-D-glucosaminitol",
            "residue": "glcnac+aldi",
            "count": 0,
            "cid": "165206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/165206"
        },
        {
            "name": "Hexose",
            "residue": "hex",
            "count": 1,
            "cid": "206",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/206"
        },
        {
            "name": "N-Acetylhexosamine",
            "residue": "hexnac",
            "count": 1,
            "cid": "899",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/899"
        },
        {
            "name": "Hexuronic Acid",
            "residue": "hexa",
            "count": 0,
            "cid": "610",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/610"
        },
        {
            "name": "2-Amino-2-Deoxy-Hexose",
            "residue": "hexn",
            "count": 0,
            "cid": "739",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/739"
        },
        {
            "name": "Hexitol",
            "residue": "hex+aldi",
            "count": 0,
            "cid": "453",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/453"
        },
        {
            "name": "N-Acetylhexosaminitol",
            "residue": "hexnac+aldi",
            "count": 0
        },
        {
            "name": "L-Iduronic acid",
            "residue": "idoa",
            "count": 0,
            "cid": "441039",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/441039"
        },
        {
            "name": "D-Mannose",
            "residue": "man",
            "count": 0,
            "cid": "18950",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/18950"
        },
        {
            "name": "D-Mannitol",
            "residue": "man+aldi",
            "count": 0,
            "cid": "6251",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/6251"
        },
        {
            "name": "N-Acetyl-D-mannosamine",
            "residue": "mannac",
            "count": 0,
            "cid": "439281",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439281"
        },
        {
            "name": "Methyl",
            "residue": "me",
            "count": 0
        },
        {
            "name": "N-Acetyl-Neuraminic Acid",
            "residue": "neuac",
            "count": 1,
            "cid": "439197",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/439197"
        },
        {
            "name": "N-Glycolyl-Neuraminic Acid",
            "residue": "neugc",
            "count": 0,
            "cid": "440001",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/440001"
        },
        {
            "name": "Phosphate",
            "residue": "p",
            "count": 0,
            "cid": "1061",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1061"
        },
        {
            "name": "Pentose",
            "residue": "pent",
            "count": 0,
            "cid": "229",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/229"
        },
        {
            "name": "Sulfate",
            "residue": "s",
            "count": 2,
            "cid": "1117",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/1117"
        },
        {
            "name": "Sialic acid",
            "residue": "sia",
            "count": 1,
            "cid": "906",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/906"
        },
        {
            "name": "Other",
            "residue": "other",
            "count": 0
        },
        {
            "name": "Floating substituent",
            "residue": "x",
            "count": 0
        },
        {
            "name": "D-Xylose",
            "residue": "xyl",
            "count": 0,
            "cid": "135191",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/135191"
        },
        {
            "name": "Ketodeoxynononic acid",
            "residue": "kdn",
            "count": 0,
            "cid": "13991616",
            "url": "https://pubchem.ncbi.nlm.nih.gov/compound/13991616"
        }
    ],
    "glycans": [
        {
            "glytoucan_ac": "G00659GQ",
            "url": "https://glytoucan.org/Structures/Glycans/G00659GQ"
        },
        {
            "glytoucan_ac": "G38852IM",
            "url": "https://glytoucan.org/Structures/Glycans/G38852IM"
        },
        {
            "glytoucan_ac": "G46799JK",
            "url": "https://glytoucan.org/Structures/Glycans/G46799JK"
        },
        {
            "glytoucan_ac": "G56318CD",
            "url": "https://glytoucan.org/Structures/Glycans/G56318CD"
        },
        {
            "glytoucan_ac": "G59594TK",
            "url": "https://glytoucan.org/Structures/Glycans/G59594TK"
        },
        {
            "glytoucan_ac": "G95837WQ",
            "url": "https://glytoucan.org/Structures/Glycans/G95837WQ"
        }
    ],
    "subsumption": [
        {
            "id": "G20710WH",
            "type": "BaseComposition"
        },
        {
            "id": "G38852IM",
            "type": "Saccharide"
        },
        {
            "id": "G46799JK",
            "type": "Saccharide"
        },
        {
            "id": "G47719KV",
            "type": "Composition"
        },
        {
            "id": "G56318CD",
            "type": "Topology"
        },
        {
            "id": "G59594TK",
            "type": "Topology"
        },
        {
            "id": "G67437JU",
            "type": "Composition"
        },
        {
            "id": "G88370GO",
            "type": "Composition"
        },
        {
            "id": "G95837WQ",
            "type": "Saccharide"
        }
    ],
    "names": [
        {
            "name": "6,6'-bisSulfo-Lewis x",
            "domain": "motifname"
        }
    ],
    "synonym": [
        "6,6'-Disulfo Sialyl Lewis x",
        "6,6'-bissulfo Le^x",
        "6,6'-bissulfo Lex"
    ],
    "keywords": [
        {
            "label": "Lewis x",
            "url": "https://glycomotif.glyomics.org/glycomotif/Lewis_x"
        }
    ],
    "reducing_end": "false",
    "aglycon": "R",
    "alignment_method": "Nonreducing-End",
    "dictionary": {
        "term": "6,6'-bisSulfo-Lewis x",
        "term_in_sentence": "Comparison of the reactivity pattern of HEV with the reactivity of the pure 6-sulfo, 6'-sulfo, or 6,6'-bissulfo sialyl Lewis X determinant with hitherto known anti-sialyl Lewis X antibodies strongly suggested 6-sulfo sialyl Lewis X to be the best  candidate for the major sulfated sialyl Lewis X determinant on HEV, followed by 6,6'-bissulfo sialyl Lewis X, whereas 6'-sulfo sialyl Lewis X was unlikely. [PMID:9556613]",
        "publication": "19756298|14593101|15175329|14568956|12163379|11919403|11520459|10728707|10200296|10528213|9712885|9556613|9456330|9556613|9257857|9164959|9015359|8958810|7560094|7485559|7538131|8161542|7684905",
        "definition": "(2S,4S,5R,6R)-5-Acetamido-2-[(2S,3R,4S,5S,6R)-2-[(2R,3S,4R,5R,6R)-5-acetamido-6-hydroxy-2-(sulfooxymethyl)-4-[(2S,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxyoxan-3-yl]oxy-3,5-dihydroxy-6-(sulfooxymethyl)oxan-4-yl]oxy-4-hydroxy-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid.[CHEBI:146095]",
        "term_xref": "GlycoEpitope:EP0016|CHEBI:146095|GlycoMotif:GGM.000028|GTC:G00659GQ",
        "synonymns": [
            "6,6'-DiSulfo Sialyl Lewis x",
            "6,6-bisSulfo-Lewis x (6,60-bissulfo Lewis x )",
            "6,6'- Disulfo Sialyl Lewis x",
            "6,6'-bisSulfo-Lewis x",
            "6,6'-bissulfo Lex",
            "6,6'-Disulfo Sialyl Lewis x",
            "6,6'-bissulfo Le^x"
        ],
        "function": "lymphocyte homing[GlycoEpitope:EP0016]",
        "disease_associations": "",
        "wikipedia": "",
        "essentials_of_glycobiology": "",
        "evidence": [
            {
                "id": "GSD000008",
                "url": "https://wiki.glygen.org/Glycan_structure_dictionary#GSD000008",
                "database": "Glycan Structure Dictionary"
            }
        ]
    },
    "biomarkers": [],
    "motif_ac": "GGM.000028",
    "section_stats": [
        {
            "table_id": "results",
            "table_stats": [
                {
                    "field": "total",
                    "count": 6
                }
            ],
            "sort_fields": [
                "glytoucan_ac",
                "url"
            ]
        }
    ]
}