{ "bcoid": "GLY_000727", "title": "Human Protein Biomarkers Citations (Biomarker Database)", "description": "Human Protein Biomarkers Citations dataset contains details of the publication present in the dataset ...", "filename": "human_protein_citations_biomarkers.csv", "filetype": "csv", "categories": { "species": [ "Homo sapiens" ], "molecule": [ "Protein" ], "tag": [ "Protein Biomarkers Citations (Biomarker Database)" ], "file_type": [ "csv" ], "status": [ "Reviewed" ], "scope": [ "internal" ] }, "minitable": { "content": [ [ "P61769-1...", "Salivary tra..." ], [ "O15123-1...", "Angiopoietin..." ] ], "headers": [ "uniprotkb_ca...", "title..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "title" }, { "type": "string", "label": "journal_name" }, { "type": "string", "label": "publication_date" }, { "type": "string", "label": "authors" }, { "type": "string", "label": "xref_key" }, { "type": "string", "label": "xref_id" }, { "type": "string", "label": "src_xref_key" }, { "type": "string", "label": "src_xref_id" } ], [ "P61769-1", "Salivary transcriptomic biomarkers for detection of ovarian cancer: for serous papillary adenocarcinoma.", "Journal of molecular medicine (Berlin, Germany)", "2012-04", "Lee Yu-Hsiang, Kim Jae Hoon, Zhou Hui, Kim Bo Wook, Wong David T", "protein_xref_pubmed", "22095100", "protein_xref_biomarkerdb", "A0466" ], [ "O15123-1", "Angiopoietin-2 gene polymorphisms are biomarkers for the development and progression of colorectal cancer in Han Chinese.", "International journal of medical sciences", "2020", "Du Z, Tang CH, Li LJ, Kang L, Zhao J, Jin L, Wang CQ, Su CM", "protein_xref_pubmed", "31929743", "protein_xref_biomarkerdb", "A0093" ], [ "Q13144-1", "Low EIF2B5 expression predicts poor prognosis in ovarian cancer.", "Medicine", "2020 Jan", "Hou L, Jiao Y, Li Y, Luo Z, Zhang X, Pan G, Zhao Y, Yang Z, He M", "protein_xref_pubmed", "32000373", "protein_xref_biomarkerdb", "A0273" ], [ "P06702-1", "COVID-19 Patients Upregulate Toll-like Receptor 4-mediated Inflammatory Signaling That Mimics Bacterial Sepsis.", "Journal of Korean medical science", "2020 Sep 28", "Sohn KM, Lee SG, Kim HJ, Cheon S, Jeong H, Lee J, Kim IS, Silwal P, Kim YJ, Paik S, Chung C, Park C, Kim YS, Jo EK", "protein_xref_pubmed", "32989935", "protein_xref_biomarkerdb", "A0134" ], [ "P11177-1", "Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer.", "OncoTargets and therapy", "2018", "Sheng M, Dong Z, Xie Y", "protein_xref_pubmed", "30532555", "protein_xref_biomarkerdb", "A0478" ], [ "P12429-1", "Expression and prognostic relevance of annexin A3 in prostate cancer.", "European urology", "2008 Dec", "Kollermann J, Schlomm T, Bang H, Schwall GP, von Eichel-Streiber C, Simon R, Schostak M, Huland H, Berg W, Sauter G, Klocker H, Schrattenholz A", "protein_xref_pubmed", "18222597", "protein_xref_biomarkerdb", "A0304" ], [ "Q6P1J9-1", "GPR137 is a promising novel bio-marker for the prognosis of bladder cancer patients.", "Medicine", "2019 Aug", "Lu J, Zhong F, Sun B, Wang C", "protein_xref_pubmed", "31464892", "protein_xref_biomarkerdb", "A0190" ], [ "P00533-1", "Immunohistochemical staining with EGFR mutation-specific antibodies: high specificity as a diagnostic marker for lung adenocarcinoma.", "Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc", "2013 Sep", "Wen YH, Brogi E, Hasanovic A, Ladanyi M, Soslow RA, Chitale D, Shia J, Moreira AL", "protein_xref_pubmed", "23599147", "protein_xref_biomarkerdb", "A0152" ], [ "Q12756-1", "NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva.", "Cancer prevention research (Philadelphia, Pa.)", "2011-07", "Guerrero-Preston R, Soudry E, Acero J, Orera M, Moreno-L\u00f3pez L, Mac\u00eda-Col\u00f3n G, Jaffe A, Berdasco M, Ili-Gangas C, Brebi-Mieville P, Fu Y, Engstrom C, Irizarry R A, Esteller M, Westra W, Koch W, Califano J, Sidransky D", "protein_xref_pubmed", "21558411", "protein_xref_biomarkerdb", "A0160" ], [ "P02144-1", "Elevated cardiac biomarkers are associated with increased mortality for inpatients with COVID-19: A retrospective case-control study.", "Journal of clinical anesthesia", "2020 Oct", "Su M, Wang Y, Peng J, Wu MJ, Deng W, Yang YS", "protein_xref_pubmed", "32450473", "protein_xref_biomarkerdb", "A0103" ], [ "Q9NYA1-1", "Predictive Value of Sphingosine Kinase 1 Expression in Papillary Thyroid Carcinoma.", "Anticancer research", "2017 Oct", "Do SI, Kim HS, Kim K, Lee H, Do IG, Kim DH, Chae SW, Sohn JH", "protein_xref_pubmed", "28982849", "protein_xref_biomarkerdb", "A0319" ], [ "Q9Y625-1", "Glypican 6 is a putative biomarker for metastatic progression of cutaneous melanoma.", "PloS one", "2019", "Li Y, Li M, Shats I, Krahn JM, Flake GP, Umbach DM, Li X, Li L", "protein_xref_pubmed", "31199813", "protein_xref_biomarkerdb", "A0179" ], [ "P21980-1", "CD44, TGM2 and EpCAM as novel plasma markers in endometrial cancer diagnosis.", "BMC cancer", "2019 Apr 29", "Torres A, Pac-Sosinska M, Wiktor K, Paszkowski T, Maciejewski R, Torres K", "protein_xref_pubmed", "31035965", "protein_xref_biomarkerdb", "A0476" ], [ "P21583-1", "Stem Cell-Based Therapy for Coronavirus Disease 2019.", "Stem cells and development", "2020 Jun 1", "Zhao RC", "protein_xref_pubmed", "32292113", "protein_xref_biomarkerdb", "A0087" ], [ "P40933-1", "VEGF-D: a novel biomarker for detection of COVID-19 progression.", "Critical care (London, England)", "2020 Jun 23", "Kong Y, Han J, Wu X, Zeng H, Liu J, Zhang H", "protein_xref_pubmed", "32576222", "protein_xref_biomarkerdb", "A0151" ], [ "P01344-1", "Diagnostic markers for early detection of ovarian cancer.", "Clinical cancer research : an official journal of the American Association for Cancer Research", "2008-02-15", "Visintin Irene, Feng Ziding, Longton Gary, Ward David C, Alvero Ayesha B, Lai Yinglei, Tenthorey Jeannette, Leiser Aliza, Flores-Saaib Ruben, Yu Herbert, Azori Masoud, Rutherford Thomas, Schwartz Peter E, Mor Gil", "protein_xref_pubmed", "18258665", "protein_xref_biomarkerdb", "A0461" ], [ "P05112-1", "The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): The Perspectives of clinical immunologists from China.", "Clinical immunology (Orlando, Fla.)", "2020 May", "Zhang W, Zhao Y, Zhang F, Wang Q, Li T, Liu Z, Wang J, Qin Y, Zhang X, Yan X, Zeng X, Zhang S", "protein_xref_pubmed", "32222466", "protein_xref_biomarkerdb", "A0045" ], [ "O60832-1", "DKC1 serves as a potential prognostic biomarker for human clear cell renal cell carcinoma and promotes its proliferation, migration and invasion via the NFkappaB pathway.", "Oncology reports", "2018 Aug", "Zhang M, Pan Y, Jiang R, Hou P, Shan H, Chen F, Jiang T, Bai J, Zheng J", "protein_xref_pubmed", "29901172", "protein_xref_biomarkerdb", "A0372" ], [ "P16422-1", "CD44, TGM2 and EpCAM as novel plasma markers in endometrial cancer diagnosis.", "BMC cancer", "2019 Apr 29", "Torres A, Pac-Sosinska M, Wiktor K, Paszkowski T, Maciejewski R, Torres K", "protein_xref_pubmed", "31035965", "protein_xref_biomarkerdb", "A0476" ], [ "P09919-1", "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.", "Lancet (London, England)", "2020 Feb 15", "Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J, Cao B", "protein_xref_pubmed", "31986264", "protein_xref_biomarkerdb", "A0043" ], [ "P01008-1", "Prominent changes in blood coagulation of patients with SARS-CoV-2 infection.", "Clinical chemistry and laboratory medicine", "2020 Jun 25", "Han H, Yang L, Liu R, Liu F, Wu KL, Li J, Liu XH, Zhu CL", "protein_xref_pubmed", "32172226", "protein_xref_biomarkerdb", "A0069" ], [ "P05231-1", "Serum interleukin 6 as a prognostic factor in patients with prostate cancer.", "Clinical cancer research : an official journal of the American Association for Cancer Research", "2000 Jul", "Nakashima J, Tachibana M, Horiguchi Y, Oya M, Ohigashi T, Asakura H, Murai M", "protein_xref_pubmed", "10914713", "protein_xref_biomarkerdb", "A0001" ], [ "P02741-1", "Clinical characteristics and outcomes of cancer patients with COVID-19.", "Journal of medical virology", "2020 Oct", "Yang F, Shi S, Zhu J, Shi J, Dai K, Chen X", "protein_xref_pubmed", "32369209", "protein_xref_biomarkerdb", "A0009" ], [ "P36956-1", "SREBP1 as a potential biomarker predicts levothyroxine efficacy of differentiated thyroid cancer.", "Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie", "2020 Mar", "Li C, Peng X, Lv J, Zou H, Liu J, Zhang K, Li Z", "protein_xref_pubmed", "31887541", "protein_xref_biomarkerdb", "A0302" ], [ "P01584-1", "Interleukin-1B-31 gene polymorphism in Hakka gastric cancer patients in Guangdong, China.", "Genetics and molecular research : GMR", "2014 Aug 7", "Qiu B, Zou HY, Yang YH, Lai CF", "protein_xref_pubmed", "25117345", "protein_xref_biomarkerdb", "A0040" ], [ "Q68CQ7-1", "GLT8D1 overexpression as a novel prognostic biomarker in human cutaneous melanoma.", "Melanoma research", "2019 Dec", "Hu H, Li Z, Zhou Y, Zhang Y, Zhao L, Zhao W, Huang Y, Song X", "protein_xref_pubmed", "31305325", "protein_xref_biomarkerdb", "A0182" ], [ "Q9Y3B8-1", "Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer.", "OncoTargets and therapy", "2018", "Sheng M, Dong Z, Xie Y", "protein_xref_pubmed", "30532555", "protein_xref_biomarkerdb", "A0478" ], [ "Q6P1J9-1", "Diagnostic Value of Serum Concentration and Integrity of Circulating Cell-Free DNA in Breast Cancer: A Comparative Study With CEA and CA15-3.", "Laboratory medicine", "2018-10-11", "Tang Zijie, Li Li, Shen Lei, Shen Xianjuan, Ju Shaoqing, Cong Hui", "protein_xref_pubmed", "29701836", "protein_xref_biomarkerdb", "A0345" ], [ "O15554-1", "KCNN4 is a diagnostic and prognostic biomarker that promotes papillary thyroid cancer progression.", "Aging", "2020 Aug 28", "Wen J, Lin B, Lin L, Chen Y, Wang O", "protein_xref_pubmed", "32857728", "protein_xref_biomarkerdb", "A0291" ], [ "Q9C0B1-1", "The N6 -methyladenosine (m6 A) erasers alkylation repair homologue 5 (ALKBH5) and fat mass and obesity-associated protein (FTO) are prognostic biomarkers in patients with clear cell renal carcinoma.", "BJU international", "2020-04", "Strick Alexander, von Hagen Felix, Gundert Larissa, Kl\u00fcmper Niklas, Tolkach Yuri, Schmidt Doris, Kristiansen Glen, Toma Marieta, Ritter Manuel, Ellinger J\u00f6rg", "protein_xref_pubmed", "31985880", "protein_xref_biomarkerdb", "A0437" ], [ "Q14116-1", "VEGF-D: a novel biomarker for detection of COVID-19 progression.", "Critical care (London, England)", "2020 Jun 23", "Kong Y, Han J, Wu X, Zeng H, Liu J, Zhang H", "protein_xref_pubmed", "32576222", "protein_xref_biomarkerdb", "A0150" ], [ "P02768-1", "Postoperative C-reactive protein/albumin ratio is a biomarker of risk of recurrence and need for adjuvant chemotherapy for stage III colorectal cancer.", "International journal of clinical oncology", "2020-07", "Matsuoka Hiroya, Ando Koji, Hu Qingjiang, Zaitsu Yoko, Tsuda Yasuo, Hisamatsu Yuichi, Nakashima Yuichiro, Kimura Yasue, Oki Eiji, Mori Masaki", "protein_xref_pubmed", "32279124", "protein_xref_biomarkerdb", "A0100" ], [ "P01008-1", "Understanding the andromeda strain - The role of cytokine release, coagulopathy and antithrombin III in SARS-CoV2 critical illness.", "Blood reviews", "2021 Jan", "Mir N, D'Amico A, Dasher J, Tolwani A, Valentine V", "protein_xref_pubmed", "32829961", "protein_xref_biomarkerdb", "A0069" ], [ "P46695-1", "Salivary transcriptomic biomarkers for detection of ovarian cancer: for serous papillary adenocarcinoma.", "Journal of molecular medicine (Berlin, Germany)", "2012-04", "Lee Yu-Hsiang, Kim Jae Hoon, Zhou Hui, Kim Bo Wook, Wong David T", "protein_xref_pubmed", "22095100", "protein_xref_biomarkerdb", "A0466" ], [ "P43694-1", "Restoration of GATA4 expression impedes breast cancer progression by transcriptional repression of ReLA and inhibition of NF-kappaB signaling.", "Journal of cellular biochemistry", "2019 Jan", "Han X, Tang J, Chen T, Ren G", "protein_xref_pubmed", "30187949", "protein_xref_biomarkerdb", "A0158" ], [ "Q99541-1", "Urinary biomarkers for the early diagnosis of kidney cancer.", "Mayo Clinic proceedings", "2010 May", "Morrissey JJ, London AN, Luo J, Kharasch ED", "protein_xref_pubmed", "20375178", "protein_xref_biomarkerdb", "A0256" ], [ "P17174-1", "The De Ritis ratio as prognostic biomarker of in-hospital mortality in COVID-19 patients.", "European journal of clinical investigation", "2021-01", "Zinellu Angelo, Arru Francesco, De Vito Andrea, Sassu Alessandro, Valdes Giovanni, Scano Valentina, Zinellu Elisabetta, Perra Roberto, Madeddu Giordano, Carru Ciriaco, Pirina Pietro, Mangoni Arduino A, Babudieri Sergio, Fois Alessandro G", "protein_xref_pubmed", "33043447", "protein_xref_biomarkerdb", "A0146" ], [ "Q8WXI7-1", "Elevations of serum cancer biomarkers correlate with severity of COVID-19.", "Journal of medical virology", "2020 Oct", "Wei X, Su J, Yang K, Wei J, Wan H, Cao X, Tan W, Wang H", "protein_xref_pubmed", "32347972", "protein_xref_biomarkerdb", "A0035" ], [ "P48061-1", "CXCL12 expression promotes esophageal squamous cell carcinoma proliferation and worsens the prognosis.", "BMC cancer", "2016 Jul 21", "Uchi Y, Takeuchi H, Matsuda S, Saikawa Y, Kawakubo H, Wada N, Takahashi T, Nakamura R, Fukuda K, Omori T, Kitagawa Y", "protein_xref_pubmed", "27439769", "protein_xref_biomarkerdb", "A0350" ], [ "Q15020-1", "Panel of serum biomarkers for the diagnosis of lung cancer.", "Journal of clinical oncology : official journal of the American Society of Clinical Oncology", "2007-12-10", "Patz Edward F, Campa Michael J, Gottlin Elizabeth B, Kusmartseva Irina, Guan Xiang Rong, Herndon James E", "protein_xref_pubmed", "18065730", "protein_xref_biomarkerdb", "A0472" ], [ "P01584-1", "An inflammatory cytokine signature helps predict COVID-19 severity and death.", "medRxiv : the preprint server for health sciences", "2020 May 30", "Del Valle DM, Kim-Schulze S, Hsin-Hui H, Beckmann ND, Nirenberg S, Wang B, Lavin Y, Swartz T, Madduri D, Stock A, Marron T, Xie H, Patel MK, van Oekelen O, Rahman A, Kovatch P, Aberg J, Schadt E, Jagannath S, Mazumdar M, Charney A, Firpo-Betancourt A, Mendu DR, Jhang J, Reich D, Sigel K, Cordon-Cardo C, Feldmann M, Parekh S, Merad M, Gnjatic S", "protein_xref_pubmed", "32511562", "protein_xref_biomarkerdb", "A0445" ], [ "Q8IZD0-1", "Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer.", "OncoTargets and therapy", "2018", "Sheng M, Dong Z, Xie Y", "protein_xref_pubmed", "30532555", "protein_xref_biomarkerdb", "A0478" ], [ "O43240-1", "The serum concentration of human kallikrein 10 represents a novel biomarker for ovarian cancer diagnosis and prognosis.", "Cancer research", "2003 Feb 15", "Luo LY, Katsaros D, Scorilas A, Fracchioli S, Bellino R, van Gramberen M, de Bruijn H, Henrik A, Stenman UH, Massobrio M, van der Zee AG, Vergote I, Diamandis EP", "protein_xref_pubmed", "12591730", "protein_xref_biomarkerdb", "A0317" ], [ "P11177-1", "Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer.", "OncoTargets and therapy", "2018", "Sheng M, Dong Z, Xie Y", "protein_xref_pubmed", "30532555", "protein_xref_biomarkerdb", "A0265" ], [ "Q8IVL1-1", "Neuron navigator-2 and cyclin D2 are new candidate prognostic markers in uterine sarcoma.", "Virchows Archiv : an international journal of pathology", "2017 Sep", "Davidson B, Hellesylt E, Holth A, Danielsen HE, Skeie-Jensen T, Katz B", "protein_xref_pubmed", "28643014", "protein_xref_biomarkerdb", "A0354" ], [ "Q9NZQ7-1", "Tumor cell PD-L1 expression is a strong predictor of unfavorable prognosis in immune checkpoint therapy-naive clear cell renal cell cancer.", "International urology and nephrology", "2021 Dec", "Moller K, Fraune C, Blessin NC, Lennartz M, Kluth M, Hube-Magg C, Lindhorst L, Dahlem R, Fisch M, Eichenauer T, Riechardt S, Simon R, Sauter G, Buscheck F, Hoppner W, Matthies C, Doh O, Krech T, Marx AH, Zecha H, Rink M, Steurer S, Clauditz TS", "protein_xref_pubmed", "33797012", "protein_xref_biomarkerdb", "A0360" ], [ "P24530-1", "NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva.", "Cancer prevention research (Philadelphia, Pa.)", "2011-07", "Guerrero-Preston R, Soudry E, Acero J, Orera M, Moreno-L\u00f3pez L, Mac\u00eda-Col\u00f3n G, Jaffe A, Berdasco M, Ili-Gangas C, Brebi-Mieville P, Fu Y, Engstrom C, Irizarry R A, Esteller M, Westra W, Koch W, Califano J, Sidransky D", "protein_xref_pubmed", "21558411", "protein_xref_biomarkerdb", "A0157" ], [ "P05231-1", "Cytokine release syndrome in severe COVID-19: interleukin-6 receptor antagonist tocilizumab may be the key to reduce mortality.", "International journal of antimicrobial agents", "2020 May", "Zhang C, Wu Z, Li JW, Zhao H, Wang GQ", "protein_xref_pubmed", "32234467", "protein_xref_biomarkerdb", "A0001" ], [ "P01375-1", "Plasma tumor necrosis factor-alpha and C-reactive protein as biomarker for survival in head and neck squamous cell carcinoma.", "Journal of cancer research and clinical oncology", "2014 Mar", "Andersson BA, Lewin F, Lundgren J, Nilsson M, Rutqvist LE, Lofgren S, Laytragoon-Lewin N", "protein_xref_pubmed", "24481866", "protein_xref_biomarkerdb", "A0028" ], [ "P19429-1", "The role of biomarkers in diagnosis of COVID-19 - A systematic review.", "Life sciences", "2020 Aug 1", "Kermali M, Khalsa RK, Pillai K, Ismail Z, Harky A", "protein_xref_pubmed", "32475810", "protein_xref_biomarkerdb", "A0065" ], [ "P05231-1", "The role of interleukin-6 in monitoring severe case of coronavirus disease 2019.", "EMBO molecular medicine", "2020-07-07", "Liu Tao, Zhang Jieying, Yang Yuhui, Ma Hong, Li Zhenyu, Zhang Jiaoyue, Cheng Ji, Zhang Xiaoyun, Zhao Yanxia, Xia Zihan, Zhang Liling, Wu Gang, Yi Jianhua", "protein_xref_pubmed", "32428990", "protein_xref_biomarkerdb", "A0001" ], [ "Q6P1J9-1", "Squamous Cellular Carcinoma Antigen Serum Determination as a Biomarker of Barrett Esophagus and Esophageal Cancer: A Phase III Study.", "Journal of clinical gastroenterology", "2018", "Maddalo Gemma, Fassan Matteo, Cardin Romilda, Piciocchi Marika, Marafatto Filippo, Rugge Massimo, Zaninotto Giovanni, Pozzan Caterina, Castoro Carlo, Ruol Alberto, Biasiolo Alessandra, Farinati Fabio", "protein_xref_pubmed", "28422774", "protein_xref_biomarkerdb", "A0195" ], [ "Q6P1J9-1", "Squamous cell carcinoma antigen-immunoglobulin M complexes as novel biomarkers for hepatocellular carcinoma.", "Cancer", "2005-06-15", "Beneduce Luca, Castaldi Francesco, Marino Maria, Quarta Santina, Ruvoletto Mariagrazia, Benvegn\u00f9 Luisa, Calabrese Fiorella, Gatta Angelo, Pontisso Patrizia, Fassina Giorgio", "protein_xref_pubmed", "15887222", "protein_xref_biomarkerdb", "A0195" ], [ "P14174-1", "Diagnostic markers for early detection of ovarian cancer.", "Clinical cancer research : an official journal of the American Association for Cancer Research", "2008-02-15", "Visintin Irene, Feng Ziding, Longton Gary, Ward David C, Alvero Ayesha B, Lai Yinglei, Tenthorey Jeannette, Leiser Aliza, Flores-Saaib Ruben, Yu Herbert, Azori Masoud, Rutherford Thomas, Schwartz Peter E, Mor Gil", "protein_xref_pubmed", "18258665", "protein_xref_biomarkerdb", "A0461" ], [ "Q6P1J9-1", "UroMark-a urinary biomarker assay for the detection of bladder cancer.", "Clinical epigenetics", "2017", "Feber Andrew, Dhami Pawan, Dong Liqin, de Winter Patricia, Tan Wei Shen, Mart\u00ednez-Fern\u00e1ndez M\u00f3nica, Paul Dirk S, Hynes-Allen Antony, Rezaee Sheida, Gurung Pratik, Rodney Simon, Mehmood Ahmed, Villacampa Felipe, de la Rosa Federico, Jameson Charles, Cheng Kar Keung, Zeegers Maurice P, Bryan Richard T, James Nicholas D, Paramio Jesus M, Freeman Alex, Beck Stephan, Kelly John D", "protein_xref_pubmed", "28163793", "protein_xref_biomarkerdb", "A0479" ], [ "Q14112-1", "NID2 and HOXA9 promoter hypermethylation as biomarkers for prevention and early detection in oral cavity squamous cell carcinoma tissues and saliva.", "Cancer prevention research (Philadelphia, Pa.)", "2011-07", "Guerrero-Preston R, Soudry E, Acero J, Orera M, Moreno-L\u00f3pez L, Mac\u00eda-Col\u00f3n G, Jaffe A, Berdasco M, Ili-Gangas C, Brebi-Mieville P, Fu Y, Engstrom C, Irizarry R A, Esteller M, Westra W, Koch W, Califano J, Sidransky D", "protein_xref_pubmed", "21558411", "protein_xref_biomarkerdb", "A0453" ], [ "Q8WTV0-1", "Up-regulation of SR-BI promotes progression and serves as a prognostic biomarker in clear cell renal cell carcinoma.", "BMC cancer", "2018 Jan 22", "Xu GH, Lou N, Shi HC, Xu YC, Ruan HL, Xiao W, Liu L, Li X, Xiao HB, Qiu B, Bao L, Yuan CF, Zhou YL, Hu WJ, Chen K, Yang HM, Zhang XP", "protein_xref_pubmed", "29357836", "protein_xref_biomarkerdb", "A0373" ], [ "P29965-1", "Clinical significance of elevated serum soluble CD40 ligand levels as a diagnostic and prognostic tumor marker for pancreatic ductal adenocarcinoma.", "Journal of translational medicine", "2014 Apr 21", "Chung HW, Lim JB", "protein_xref_pubmed", "24745825", "protein_xref_biomarkerdb", "A0119" ], [ "P04637-1", "Evaluation of paraneoplastic antigens reveals TRIM21 autoantibodies as biomarker for early detection of ovarian cancer in combination with autoantibodies to NY-ESO-1 and TP53.", "Cancer biomarkers : section A of Disease markers", "2020", "Hurley Laura C, Levin Nancy K, Chatterjee Madhumita, Coles Jasmine, Muszkat Shlomo, Howarth Zachary, Dyson Gregory, Tainsky Michael A", "protein_xref_pubmed", "32083570", "protein_xref_biomarkerdb", "A0464" ], [ "Q8WXI7-1", "A novel multiple biomarker panel for the early detection of high-grade serous ovarian carcinoma.", "Gynecologic oncology", "2018-06", "Han Chanhee, Bellone Stefania, Siegel Eric R, Altwerger Gary, Menderes Gulden, Bonazzoli Elena, Egawa-Takata Tomomi, Pettinella Francesca, Bianchi Anna, Riccio Francesco, Zammataro Luca, Yadav Ghanshyam, Marto Jarrod A, Penet Marie-France, Levine Douglas A, Drapkin Ronny, Patel Abhijit, Litkouhi Babak, Ratner Elena, Silasi Dan-Arin, Huang Gloria S, Azodi Masoud, Schwartz Peter E, Santin Alessandro D", "protein_xref_pubmed", "29572027", "protein_xref_biomarkerdb", "A0456" ], [ "Q14508-1", "Elevations of serum cancer biomarkers correlate with severity of COVID-19.", "Journal of medical virology", "2020 Oct", "Wei X, Su J, Yang K, Wei J, Wan H, Cao X, Tan W, Wang H", "protein_xref_pubmed", "32347972", "protein_xref_biomarkerdb", "A0032" ], [ "Q96PU8-1", "Quaking I-5 protein inhibits invasion and migration of kidney renal clear cell carcinoma via inhibiting epithelial-mesenchymal transition suppression through the regulation of microRNA 200c.", "Translational andrology and urology", "2021 Oct", "Zhang R, Wang W, Aimudula A, Lu S, Lu P, Aihaiti R, Bao Y", "protein_xref_pubmed", "34804823", "protein_xref_biomarkerdb", "A0374" ], [ "P02741-1", "Plasma tumor necrosis factor-alpha and C-reactive protein as biomarker for survival in head and neck squamous cell carcinoma.", "Journal of cancer research and clinical oncology", "2014 Mar", "Andersson BA, Lewin F, Lundgren J, Nilsson M, Rutqvist LE, Lofgren S, Laytragoon-Lewin N", "protein_xref_pubmed", "24481866", "protein_xref_biomarkerdb", "A0009" ], [ "P01236-1", "Diagnostic markers for early detection of ovarian cancer.", "Clinical cancer research : an official journal of the American Association for Cancer Research", "2008-02-15", "Visintin Irene, Feng Ziding, Longton Gary, Ward David C, Alvero Ayesha B, Lai Yinglei, Tenthorey Jeannette, Leiser Aliza, Flores-Saaib Ruben, Yu Herbert, Azori Masoud, Rutherford Thomas, Schwartz Peter E, Mor Gil", "protein_xref_pubmed", "18258665", "protein_xref_biomarkerdb", "A0461" ], [ "P22607-1", "Expression levels of FGFR3 as a prognostic marker for the progression of primary pT1 bladder cancer and its association with mutation status.", "Oncology letters", "2017 Sep", "Kang HW, Kim YH, Jeong P, Park C, Kim WT, Ryu DH, Cha EJ, Ha YS, Kim TH, Kwon TG, Moon SK, Choi YH, Yun SJ, Kim WJ", "protein_xref_pubmed", "28927152", "protein_xref_biomarkerdb", "A0384" ], [ "P46013-1", "Prognostic significance of pathologic complete response and Ki67 expression after neoadjuvant chemotherapy in breast cancer.", "Breast cancer (Tokyo, Japan)", "2015 Mar", "Yoshioka T, Hosoda M, Yamamoto M, Taguchi K, Hatanaka KC, Takakuwa E, Hatanaka Y, Matsuno Y, Yamashita H", "protein_xref_pubmed", "23645542", "protein_xref_biomarkerdb", "A0254" ], [ "P10451-1", "Preoperative plasma osteopontin level as a biomarker complementary to carbohydrate antigen 125 in predicting ovarian cancer.", "The journal of obstetrics and gynaecology research", "2006-06", "Nakae Mitsuhiro, Iwamoto Ichiro, Fujino Toshinori, Maehata Yoshiyasu, Togami Shin-ichi, Yoshinaga Mitsuhiro, Douchi Tsutomu", "protein_xref_pubmed", "16764622", "protein_xref_biomarkerdb", "A0471" ], [ "Q9H8U3-1", "Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer.", "OncoTargets and therapy", "2018", "Sheng M, Dong Z, Xie Y", "protein_xref_pubmed", "30532555", "protein_xref_biomarkerdb", "A0478" ], [ "P19440-1", "Gamma-glutamyltransferase as novel biomarker in patients with uterine leiomyosarcoma.", "Scientific reports", "2016 Sep 20", "Schwameis R, Grimm C, Brodowicz T, Petru E, Hefler-Frischmuth K, Staudigl C, Reinthaller A, Heinze G, Polterauer S, Polterauer M", "protein_xref_pubmed", "27646551", "protein_xref_biomarkerdb", "A0347" ], [ "Q9UN36-1", "Expression of N-Myc Downstream-Regulated Gene 2 in Bladder Cancer and Its Potential Utility as a Urinary Diagnostic Biomarker.", "Medical science monitor : international medical journal of experimental and clinical research", "2017 Sep 27", "Zhang M, Ren B, Li Z, Niu W, Wang Y", "protein_xref_pubmed", "28953854", "protein_xref_biomarkerdb", "A0173" ], [ "A4D0V7-1", "Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer.", "OncoTargets and therapy", "2018", "Sheng M, Dong Z, Xie Y", "protein_xref_pubmed", "30532555", "protein_xref_biomarkerdb", "A0478" ], [ "P21583-1", "Transplantation of ACE2(-) Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia.", "Aging and disease", "2020 Apr", "Leng Z, Zhu R, Hou W, Feng Y, Yang Y, Han Q, Shan G, Meng F, Du D, Wang S, Fan J, Wang W, Deng L, Shi H, Li H, Hu Z, Zhang F, Gao J, Liu H, Li X, Zhao Y, Yin K, He X, Gao Z, Wang Y, Yang B, Jin R, Stambler I, Lim LW, Su H, Moskalev A, Cano A, Chakrabarti S, Min KJ, Ellison-Hughes G, Caruso C, Jin K, Zhao RC", "protein_xref_pubmed", "32257537", "protein_xref_biomarkerdb", "A0087" ], [ "Q9UHK6-1", "Prostate cancer detection on urinalysis for alpha methylacyl coenzyme a racemase protein.", "The Journal of urology", "2004 Oct", "Rogers CG, Yan G, Zha S, Gonzalgo ML, Isaacs WB, Luo J, De Marzo AM, Nelson WG, Pavlovich CP", "protein_xref_pubmed", "15371879", "protein_xref_biomarkerdb", "A0282" ], [ "P52566-1", "Systematic investigation of biomarker-like role of ARHGDIB in breast cancer.", "Cancer biomarkers : section A of Disease markers", "2020", "Wang X, Bi X, Huang X, Wang B, Guo Q, Wu Z", "protein_xref_pubmed", "32176626", "protein_xref_biomarkerdb", "A0204" ], [ "Q6P1J9-1", "Neutrophil extracellular traps (NETs) as markers of disease severity in COVID-19.", "medRxiv : the preprint server for health sciences", "2020-04-14", "Zuo Yu, Yalavarthi Srilakshmi, Shi Hui, Gockman Kelsey, Zuo Melanie, Madison Jacqueline A, Blair Christopher, Weber Andrew, Barnes Betsy J, Egeblad Mikala, Woods Robert J, Kanthi Yogendra, Knight Jason S", "protein_xref_pubmed", "32511633", "protein_xref_biomarkerdb", "A0074" ], [ "P04275-1", "von Willebrand factor is a useful biomarker for liver fibrosis and prediction of hepatocellular carcinoma development in patients with hepatitis B and C.", "United European gastroenterology journal", "2018 Nov", "Takaya H, Kawaratani H, Tsuji Y, Nakanishi K, Saikawa S, Sato S, Sawada Y, Kaji K, Okura Y, Shimozato N, Kitade M, Akahane T, Moriya K, Namisaki T, Mitoro A, Matsumoto M, Fukui H, Yoshiji H", "protein_xref_pubmed", "30386613", "protein_xref_biomarkerdb", "A0117" ], [ "Q9BYF1-1", "Decreased expression of angiotensin-converting enzyme 2 in pancreatic ductal adenocarcinoma is associated with tumor progression.", "The Tohoku journal of experimental medicine", "2009 Feb", "Zhou L, Zhang R, Yao W, Wang J, Qian A, Qiao M, Zhang Y, Yuan Y", "protein_xref_pubmed", "19212105", "protein_xref_biomarkerdb", "A0031" ], [ "Q8TEA8-1", "Identification of tumor-educated platelet biomarkers of non-small-cell lung cancer.", "OncoTargets and therapy", "2018", "Sheng M, Dong Z, Xie Y", "protein_xref_pubmed", "30532555", "protein_xref_biomarkerdb", "A0478" ], [ "P06731-1", "Panel of serum biomarkers for the diagnosis of lung cancer.", "Journal of clinical oncology : official journal of the American Society of Clinical Oncology", "2007-12-10", "Patz Edward F, Campa Michael J, Gottlin Elizabeth B, Kusmartseva Irina, Guan Xiang Rong, Herndon James E", "protein_xref_pubmed", "18065730", "protein_xref_biomarkerdb", "A0472" ], [ "P01584-1", "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.", "Lancet (London, England)", "2020 Feb 15", "Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y, Zhang L, Fan G, Xu J, Gu X, Cheng Z, Yu T, Xia J, Wei Y, Wu W, Xie X, Yin W, Li H, Liu M, Xiao Y, Gao H, Guo L, Xie J, Wang G, Jiang R, Gao Z, Jin Q, Wang J, Cao B", "protein_xref_pubmed", "31986264", "protein_xref_biomarkerdb", "A0445" ], [ "Q6P1J9-1", "A review of causes and systemic approach to cardiac troponin elevation.", "Clinical cardiology", "2011-12", "Patil Harshal, Vaidya Omkar, Bogart Douglas", "protein_xref_pubmed", "22120679", "protein_xref_biomarkerdb", "A0029" ], [ "P59052-1", "Serum level of long noncoding RNA B3GALT5-AS1 as a diagnostic biomarker of colorectal cancer.", "Future oncology (London, England)", "2020 May", "Ding Y, Feng W, Ge JK, Dai L, Liu TT, Hua XY, Lu X, Ju SQ, Yu J", "protein_xref_pubmed", "32207329", "protein_xref_biomarkerdb", "A0209" ], [ "P21333-1", "Identification of candidate prostate cancer biomarkers in prostate needle biopsy specimens using proteomic analysis.", "International journal of cancer", "2007 Dec 15", "Lin JF, Xu J, Tian HY, Gao X, Chen QX, Gu Q, Xu GJ, Song JD, Zhao FK", "protein_xref_pubmed", "17722004", "protein_xref_biomarkerdb", "A0262" ], [ "O94875-1", "RNA-binding protein SORBS2 suppresses clear cell renal cell carcinoma metastasis by enhancing MTUS1 mRNA stability.", "Cell death & disease", "2020 Dec 12", "Lv Q, Dong F, Zhou Y, Cai Z, Wang G", "protein_xref_pubmed", "33311452", "protein_xref_biomarkerdb", "A0375" ] ] }, "readme": "Name\n - Human Protein Biomarkers Citations (Biomarker Database)\n\nVersion\n - v-2.3.1\n\nCreated on\n - 2023-03-03T02:24:59.574Z\n\nModified on\n - 2023-03-03T02:40:02.789Z\n\nCreated by\n - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n - \n\nChecksum\n - \n\nUsability Domain\n - Human Protein Biomarkers Citations dataset contains details of the publication present in the dataset Human Protein Cancer Biomarkers https://data.glygen.org/GLY_000625\n\nDescription Domain\n Keywords\n - Biomarkers\n - BiomarkerDB\n\n Pipeline Steps\n - Step-1: The script extracts the PMID from the dataset and uses the Entrez API to retrieve the publication details and extracts in a csv dataset\n\nExecution Domain\n Scripts - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: human_protein_biomarkers.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/human_protein_biomarkers.csv\n Output Subdomain\n Name: human_protein_citations_biomarkers.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/human_protein_citations_biomarkers.csv\n Name: human_protein_citations_biomarkers.stat.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/human_protein_citations_biomarkers.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"306\"\n Name: \"title\"\n Description: \"Title of the published article in the journal\"\n Unique Values: \"379\"\n Name: \"journal_name\"\n Description: \"The name of the journal in which the article is published\"\n Unique Values: \"235\"\n Name: \"publication_date\"\n Description: \"Contains the full date on which the issue of the journal was published. Sourced from MEDLINE/PubMed data element(fields) description.\"\n Unique Values: \"264\"\n Name: \"authors\"\n Description: \"NA\"\n Unique Values: \"379\"\n Name: \"xref_key\"\n Description: \"Source key associated to the xref_id\"\n Unique Values: \"1\"\n Name: \"xref_id\"\n Description: \"ID of the X-ref\"\n Unique Values: \"379\"\n Name: \"src_xref_key\"\n Description: \"Source Xref key\"\n Unique Values: \"1\"\n Name: \"src_xref_id\"\n Description: \"Source X-ref ID\"\n Unique Values: \"289\"", "downloadurl": "/ln2data/releases/data/v-2.3.1/reviewed/human_protein_citations_biomarkers.csv" }