{ "bcoid": "GLY_000685", "title": "Fruitfly Glycohydrolases", "description": "The Fruitfly Glycohydrolases dataset contains a list of fruitfly [taxid:7227] glycohydrolases derived ...", "filename": "fruitfly_protein_glycohydrolase.csv", "filetype": "csv", "categories": { "species": [ "Drosophila melanogaster" ], "molecule": [ "Protein" ], "tag": [ "Glycohydrolases" ], "file_type": [ "csv" ], "status": [ "Reviewed" ], "scope": [ "internal" ] }, "minitable": { "content": [ [ "P08144-1...", "Drosophila m..." ], [ "P53624-1...", "Drosophila m..." ] ], "headers": [ "uniprotkb_ca...", "organism..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "organism" }, { "type": "string", "label": "status" }, { "type": "string", "label": "gene_symbol" }, { "type": "string", "label": "uniprotkb_protein_name" }, { "type": "string", "label": "ec_number" }, { "type": "string", "label": "brenda_ec_number" }, { "type": "string", "label": "cazy_gh_gamily" }, { "type": "string", "label": "interpro_id" }, { "type": "string", "label": "pfam_ac" }, { "type": "string", "label": "go_molecular_function" } ], [ "P08144-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Amy-p", "Alpha-amylase A, EC 3.2.1.1 (1,4-alpha-D-glucan glucanohydrolase)", "3.2.1.1", "3.2.1.1", "GH13", "IPR006048|IPR031319|IPR006046|IPR006047|IPR013780|IPR017853", "PF00128|PF02806", "alpha-amylase activity [GO:0004556]| calcium ion binding [GO:0005509]" ], [ "P53624-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "alpha-Man-Ia", "Mannosyl-oligosaccharide alpha-1,2-mannosidase IA, EC 3.2.1.113 (Man(9)-alpha-mannosidase) (Mannosidase-1)", "3.2.1.113", "", "GH47", "IPR012341|IPR001382|IPR036026", "PF01532", "calcium ion binding [GO:0005509]| mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]" ], [ "P81641-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Amy-d", "Alpha-amylase B, EC 3.2.1.1 (1,4-alpha-D-glucan glucanohydrolase)", "3.2.1.1", "", "GH13", "IPR006048|IPR031319|IPR006046|IPR006047|IPR013780|IPR017853", "PF00128|PF02806", "alpha-amylase activity [GO:0004556]| calcium ion binding [GO:0005509]" ], [ "Q24451-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "alpha-Man-IIa", "Alpha-mannosidase 2, EC 3.2.1.114 (Golgi alpha-mannosidase II, AMan II, Man II) (Golgi alpha-mannosidase IIa) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase)", "3.2.1.114", "3.2.1.114", "GH38", "IPR041566|IPR011013|IPR011330|IPR011682|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780", "PF09261|PF18230|PF07748|PF01074", "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| mannosidase activity [GO:0015923]| mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity [GO:0004572]| metal ion binding [GO:0046872]" ], [ "Q8WSF3-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "fdl", "Probable beta-hexosaminidase fdl, EC 3.2.1.52 (Protein fused lobes)", "3.2.1.52", "", "GH20", "IPR025705|IPR015883|IPR017853|IPR029018|IPR029019", "PF00728|PF14845", "beta-N-acetylglucosaminidase activity [GO:0016231]| beta-N-acetylhexosaminidase activity [GO:0004563]| N-acetyl-beta-D-galactosaminidase activity [GO:0102148]" ], [ "Q9W092-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Cht2", "Probable chitinase 2, EC 3.2.1.14", "3.2.1.14", "", "GH18", "IPR011583|IPR029070|IPR001223|IPR001579|IPR017853", "PF00704", "chitin binding [GO:0008061]| chitinase activity [GO:0004568]" ], [ "Q9W2M2-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Treh", "Trehalase, EC 3.2.1.28 (Alpha,alpha-trehalase) (Alpha,alpha-trehalose glucohydrolase)", "3.2.1.28", "3.2.1.28", "GH37", "IPR008928|IPR012341|IPR001661|IPR018232", "PF01204", "alpha,alpha-trehalase activity [GO:0004555]" ], [ "O18408-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Amyrel", "Alpha-amylase-related protein, EC 3.2.1.1", "3.2.1.1", "", "GH13", "IPR006048|IPR031319|IPR006046|IPR006047|IPR013780|IPR017853", "PF00128|PF02806", "4-alpha-glucanotransferase activity [GO:0004134]| alpha-amylase activity [GO:0004556]| amylase activity [GO:0016160]| metal ion binding [GO:0046872]" ], [ "P29615-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "LysP", "Lysozyme P, EC 3.2.1.17 (1,4-beta-N-acetylmuramidase P)", "3.2.1.17", "", "GH22", "IPR001916|IPR019799|IPR000974|IPR023346", "PF00062", "lysozyme activity [GO:0003796]" ], [ "P37159-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "LysE", "Lysozyme E, EC 3.2.1.17 (1,4-beta-N-acetylmuramidase E)", "3.2.1.17", "", "GH22", "IPR001916|IPR019799|IPR000974|IPR023346", "PF00062", "lysozyme activity [GO:0003796]" ], [ "P37161-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "LysX", "Lysozyme X, EC 3.2.1.17 (1,4-beta-N-acetylmuramidase X)", "3.2.1.17", "", "GH22", "IPR001916|IPR019799|IPR000974|IPR023346", "PF00062", "lysozyme activity [GO:0003796]" ], [ "P83972-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "LysD", "Lysozyme D, EC 3.2.1.17 (1,4-beta-N-acetylmuramidase D)", "3.2.1.17", "", "GH22", "IPR001916|IPR019799|IPR000974|IPR023346", "PF00062", "chitinase activity [GO:0004568]| lysozyme activity [GO:0003796]" ], [ "Q7KT91-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "", "Non-lysosomal glucosylceramidase, NLGase, EC 3.2.1.45", "3.2.1.45", "", "GH116", "IPR008928|IPR012341|IPR014551|IPR006775|IPR024462", "PF04685|PF12215", "beta-glucosidase activity [GO:0008422]| glucosylceramidase activity [GO:0004348]| glucosyltransferase activity [GO:0046527]" ], [ "Q8IMY3-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Gba1b", "Glucosylceramidase, EC 3.2.1.45", "3.2.1.45", "", "GH30", "IPR033452|IPR001139|IPR033453|IPR017853", "PF02055|PF17189", "glucosylceramidase activity [GO:0004348]| glucosyltransferase activity [GO:0046527]" ], [ "Q8IPB7-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "LManII", "Alpha-mannosidase, EC 3.2.1.-", "3.2.1.-", "", "GH38", "IPR011013|IPR041147|IPR011330|IPR011682|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780", "PF09261|PF17677|PF07748|PF01074", "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]| metal ion binding [GO:0046872]" ], [ "Q9V9T9-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "betaGlu", "Beta-glucuronidase, EC 3.2.1.31", "3.2.1.31", "", "GH2", "IPR036156|IPR008979|IPR006101|IPR006103|IPR023230|IPR006102|IPR006104|IPR017853|IPR013783", "PF00703|PF02836|PF02837", "beta-glucuronidase activity [GO:0004566]| carbohydrate binding [GO:0030246]" ], [ "Q9VCJ4-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Gba1a", "Glucosylceramidase, EC 3.2.1.45", "3.2.1.45", "", "GH30", "IPR033452|IPR001139|IPR033453|IPR013780|IPR017853", "PF02055|PF17189", "glucosylceramidase activity [GO:0004348]| glucosyltransferase activity [GO:0046527]" ], [ "Q9VMJ5-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Gal", "Beta-galactosidase, EC 3.2.1.23 (Acid beta-galactosidase)", "3.2.1.23", "", "GH35", "IPR026283|IPR025300|IPR008979|IPR031330|IPR001944|IPR017853", "PF13364|PF01301", "beta-galactosidase activity [GO:0004565]| protein homodimerization activity [GO:0042803]" ], [ "Q9VTJ4-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Fuca", "Putative alpha-L-fucosidase, EC 3.2.1.51 (Alpha-L-fucoside fucohydrolase)", "3.2.1.51", "3.2.1.51", "GH29", "IPR016286|IPR031919|IPR000933|IPR013780|IPR017853", "PF01120|PF16757", "alpha-L-fucosidase activity [GO:0004560]| fucose binding [GO:0042806]" ], [ "Q9W3C4-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Hexo2", "Beta-N-acetylhexosaminidase, EC 3.2.1.52", "3.2.1.52", "", "GH20", "IPR025705|IPR015883|IPR017853|IPR029018|IPR029019", "PF00728|PF14845", "beta-N-acetylglucosaminidase activity [GO:0016231]| beta-N-acetylhexosaminidase activity [GO:0004563]| N-acetyl-beta-D-galactosaminidase activity [GO:0102148]" ], [ "Q9W5U2-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Cht10", "Probable chitinase 10, EC 3.2.1.14 (Probable chitinase 1) (Probable chitinase 3)", "3.2.1.14", "", "CBM14|GH18", "IPR002557|IPR036508|IPR011583|IPR029070|IPR001223|IPR001579|IPR017853", "PF01607|PF00704", "chitin binding [GO:0008061]| chitinase activity [GO:0004568]" ], [ "P07190-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Mal-A1", "Maltase A1, EC 3.2.1.20 (Larval visceral protein H)", "3.2.1.20", "", "GH13", "IPR006047|IPR013780|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "P07191-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Mal-A2", "Maltase A2, EC 3.2.1.20 (Larval visceral protein D)", "3.2.1.20", "", "GH13", "IPR006047|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "P07192-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "Mal-A3", "Maltase A3, EC 3.2.1.20 (Larval visceral protein L)", "3.2.1.20", "", "GH13", "IPR006047|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "P37160-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "LysS", "Lysozyme S, EC 3.2.1.17 (1,4-beta-N-acetylmuramidase S)", "3.2.1.17", "", "GH22", "IPR001916|IPR019799|IPR000974|IPR023346", "PF00062", "lysozyme activity [GO:0003796]" ], [ "Q08694-1", "Drosophila melanogaster (Fruit fly)", "reviewed", "LysB", "Lysozyme B, EC 3.2.1.17 (1,4-beta-N-acetylmuramidase B)", "3.2.1.17", "", "GH22", "IPR001916|IPR019799|IPR000974|IPR023346", "PF00062", "lysozyme activity [GO:0003796]" ], [ "Q9W2H8-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Dmel\\CG9485", "Glycogen debranching enzyme, EC 2.4.1.25, EC 3.2.1.33 (Glycogen debrancher)", "2.4.1.25| 3.2.1.33", "", "GH13|GH133", "IPR008928|IPR012341|IPR010401|IPR032788|IPR029436|IPR032792|IPR032790|IPR006421|IPR017853", "PF06202|PF14701|PF14702|PF14699", "4-alpha-glucanotransferase activity [GO:0004134]| amylo-alpha-1,6-glucosidase activity [GO:0004135]| beta-maltose 4-alpha-glucanotransferase activity [GO:0102500]" ], [ "Q9VGE7-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Ect3", "Beta-galactosidase, EC 3.2.1.23", "3.2.1.23", "", "GH35", "IPR026283|IPR025300|IPR008979|IPR031330|IPR019801|IPR001944|IPR017853", "PF13364|PF01301", "beta-galactosidase activity [GO:0004565]" ], [ "A0A0B4KGE4-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "CD98hc", "Alpha-glucosidase, EC 3.2.1.20", "3.2.1.20", "", "GH13", "IPR006047|IPR013780|IPR017853|IPR045857|IPR042280|IPR031984", "PF00128|PF16028", "hydrolase activity, acting on glycosyl bonds [GO:0016798]" ], [ "Q9VZ04-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "GCS1", "Mannosyl-oligosaccharide glucosidase, EC 3.2.1.106", "3.2.1.106", "", "GH63", "IPR008928|IPR012341|IPR031335|IPR031631|IPR038518|IPR004888", "PF03200|PF16923", "Glc3Man9GlcNAc2 oligosaccharide glucosidase activity [GO:0004573]" ], [ "A1Z7E8-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Mal-A4", "Alpha-glucosidase, EC 3.2.1.20", "3.2.1.20", "", "GH13", "IPR006047|IPR013780|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "A1Z7F1-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Mal-A6", "Alpha-glucosidase, EC 3.2.1.20", "3.2.1.20", "", "GH13", "IPR006047|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "A1Z7F2-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Mal-A7", "Alpha-glucosidase, EC 3.2.1.20", "3.2.1.20", "", "GH13", "IPR006047|IPR013780|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "A1Z7F3-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Mal-A8", "Alpha-glucosidase, EC 3.2.1.20", "3.2.1.20", "", "GH13", "IPR006047|IPR013780|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "A1ZAL1-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "EG:EG0003.8", "Lysozyme, EC 3.2.1.17", "3.2.1.17", "", "GH22", "IPR008597|IPR023346", "PF05497", "lysozyme activity [GO:0003796]" ], [ "Q5U124-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Mal-A5", "Alpha-glucosidase, EC 3.2.1.20", "3.2.1.20", "", "GH13", "IPR006047|IPR013780|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "A0A4P1SA55-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Mal-B2", "Alpha-glucosidase, EC 3.2.1.20", "3.2.1.20", "", "GH13", "IPR006047|IPR013780|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "Q9VKE6-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "Mal-B1", "Alpha-glucosidase, EC 3.2.1.20", "3.2.1.20", "", "GH13", "IPR006047|IPR013780|IPR017853|IPR045857", "PF00128", "maltose alpha-glucosidase activity [GO:0032450]" ], [ "Q9VKV2-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "LManI", "Alpha-mannosidase, EC 3.2.1.-", "3.2.1.-", "", "GH38", "IPR011013|IPR041147|IPR011330|IPR011682|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780", "PF09261|PF17677|PF07748|PF01074", "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| mannosyl-oligosaccharide 1,2-alpha-mannosidase activity [GO:0004571]| metal ion binding [GO:0046872]" ], [ "Q9VLI0-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "LManV", "Alpha-mannosidase, EC 3.2.1.-", "3.2.1.-", "", "GH38", "IPR011013|IPR041147|IPR011330|IPR011682|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780", "PF09261|PF17677|PF07748|PF01074", "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]" ], [ "Q9VLI1-1", "Drosophila melanogaster (Fruit fly)", "unreviewed", "LManIV", "Alpha-mannosidase, EC 3.2.1.-", "3.2.1.-", "", "GH38", "IPR011013|IPR041147|IPR011330|IPR011682|IPR015341|IPR037094|IPR000602|IPR027291|IPR028995|IPR013780", "PF09261|PF17677|PF07748|PF01074", "alpha-mannosidase activity [GO:0004559]| carbohydrate binding [GO:0030246]| metal ion binding [GO:0046872]" ] ] }, "readme": "Name\n - Fruitfly Glycohydrolases\n\nVersion\n - v-2.3.1\n\nCreated on\n - 2022-09-06T11:23:37.687653\n\nModified on\n - 2022-09-26T09:08:12.673905\n\nCreated by\n - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n - \n\nChecksum\n - \n\nUsability Domain\n - The Fruitfly Glycohydrolases dataset contains a list of fruitfly [taxid:7227] glycohydrolases derived from UniProtKB database using advanced search and other databases including CAZy, InterPro and Pfam.If you use this dataset please provide proper attribution to UniProtKB and GlyGen\n\nDescription Domain\n Keywords\n - glycohydrolase\n - glycosidase\n - EC Number\n - CAZy\n\n Pipeline Steps\n - Step-1: The script maps and replaces the UniProtKB accession to the UniProtKB canonical accession\n\nExecution Domain\n Scripts - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: fruitfly_protein_glycohydrolase.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/compiled/fruitfly_protein_glycohydrolase.csv\n Name: fruitfly_protein_masterlist.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/fruitfly_protein_masterlist.csv\n Output Subdomain\n Name: fruitfly_protein_glycohydrolase.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/fruitfly_protein_glycohydrolase.csv\n Name: fruitfly_protein_glycohydrolase.stat.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/fruitfly_protein_glycohydrolase.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"41\"\n Name: \"organism\"\n Description: \"Name of the species\"\n Unique Values: \"1\"\n Name: \"status\"\n Description: \"Status of the protein record in UniProtKB database that can be reviewed for UniProtKB/Swiss-Prot entry or unreviewed for UniProtKB/TrEMBL entry\"\n Unique Values: \"2\"\n Name: \"gene_symbol\"\n Description: \"\"Official gene name/symbol assigned to the gene. Human gene names/symbols are approved by the HUGO Gene Nomenclature Committee (HGNC)\"\n Unique Values: \"41\"\n Name: \"uniprotkb_protein_name\"\n Description: \"Name of the protein in UniProtKB database\"\n Unique Values: \"30\"\n Name: \"ec_number\"\n Description: \"Enzyme Commision number assigned to an enzyme by Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB)\"\n Unique Values: \"15\"\n Name: \"brenda_ec_number\"\n Description: \"Enzyme Commission (EC) number assigned to enzyme in BRENDA database\"\n Unique Values: \"5\"\n Name: \"cazy_gh_gamily\"\n Description: \"The family assigned to glycohydrolase in the CAZy database\"\n Unique Values: \"15\"\n Name: \"interpro_id\"\n Description: \"InterPro Identifier\"\n Unique Values: \"22\"\n Name: \"pfam_ac\"\n Description: \"Accession assigned to the protein family in the Pfam database\"\n Unique Values: \"19\"\n Name: \"go_molecular_function\"\n Description: \"\"The elemental activities of a gene product at the molecular level\"\n Unique Values: \"21\"", "downloadurl": "/ln2data/releases/data/v-2.3.1/reviewed/fruitfly_protein_glycohydrolase.csv" }