{ "bcoid": "GLY_000568", "title": "Mouse Proteoform Phosphorylation Citations (iPTMnet)", "description": "", "filename": "mouse_proteoform_citations_phosphorylation_sites_iptmnet.csv", "filetype": "csv", "categories": { "species": [ "Mus musculus" ], "molecule": [ "Proteoform" ], "tag": [ "Phosphorylation Citations (iPTMnet)" ], "file_type": [ "csv" ], "status": [ "Reviewed" ], "scope": [ "internal" ] }, "minitable": { "content": [ [ "E9PYG6-1...", "Investigatio..." ], [ "O08553-1...", "Cdk5-mediate..." ] ], "headers": [ "uniprotkb_ca...", "title..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "title" }, { "type": "string", "label": "journal_name" }, { "type": "string", "label": "publication_date" }, { "type": "string", "label": "authors" }, { "type": "string", "label": "xref_key" }, { "type": "string", "label": "xref_id" }, { "type": "string", "label": "src_xref_key" }, { "type": "string", "label": "src_xref_id" } ], [ "E9PYG6-1", "Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.", "Molecular & cellular proteomics : MCP", "2008-09", "Mertins Philipp, Eberl H Christian, Renkawitz J\u00f6rg, Olsen Jesper V, Tremblay Michel L, Mann Matthias, Ullrich Axel, Daub Henrik", "protein_xref_pubmed", "18515860", "protein_xref_iptmnet", "E9PYG6" ], [ "O08553-1", "Cdk5-mediated phosphorylation of CRMP-2 enhances its interaction with CaV2.2.", "FEBS letters", "2012-11-02", "Brittain Joel M, Wang Yuying, Eruvwetere Omotore, Khanna Rajesh", "protein_xref_pubmed", "23022559", "protein_xref_iptmnet", "O08553" ], [ "O09127-1", "Phosphorylation at Tyr-838 in the kinase domain of EphA8 modulates Fyn binding to the Tyr-615 site by enhancing tyrosine kinase activity.", "Oncogene", "1999 Sep 23", "Choi S, Park S", "protein_xref_pubmed", "10498895", "protein_xref_iptmnet", "O09127" ], [ "O35601-1", "ADAP-SLP-76 binding differentially regulates supramolecular activation cluster (SMAC) formation relative to T cell-APC conjugation.", "The Journal of experimental medicine", "2004-10-18", "Wang Hongyan, McCann Fiona E, Gordan John D, Wu Xiang, Raab Monika, Malik Talat H, Davis Daniel M, Rudd Christopher E", "protein_xref_pubmed", "15477347", "protein_xref_iptmnet", "O35601" ], [ "O70405-1", "Phosphorylation of ULK1 by AMPK regulates translocation of ULK1 to mitochondria and mitophagy.", "FEBS letters", "2015-07-08", "Tian Weili, Li Wen, Chen Yinqin, Yan Zeming, Huang Xia, Zhuang Haixia, Zhong Wangtao, Chen Yusen, Wu Wenxian, Lin Chunxia, Chen Hao, Hou Xiaoyan, Zhang Liangqing, Sui Senfang, Zhao Bin, Hu Zhe, Li Longxuan, Feng Du", "protein_xref_pubmed", "25980607", "protein_xref_iptmnet", "O70405" ], [ "O70469-1", "Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak.", "The EMBO journal", "2001 Nov 1", "Master Z, Jones N, Tran J, Jones J, Kerbel RS, Dumont DJ", "protein_xref_pubmed", "11689432", "protein_xref_iptmnet", "O70469" ], [ "P05132-1", "Phosphoryl transfer by protein kinase A is captured in a crystal lattice.", "Journal of the American Chemical Society", "2013 Mar 27", "Bastidas AC, Deal MS, Steichen JM, Guo Y, Wu J, Taylor SS", "protein_xref_pubmed", "23458248", "protein_xref_iptmnet", "P05132" ], [ "P05480-2", "Roles of the SH2 and SH3 domains in the regulation of neuronal Src kinase functions.", "The FEBS journal", "2011-02", "Groveman Bradley R, Xue Sheng, Marin Vedrana, Xu Jindong, Ali Mohammad K, Bienkiewicz Ewa A, Yu Xian-Min", "protein_xref_pubmed", "21199370", "protein_xref_iptmnet", "P05480" ], [ "P05532-1", "SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.", "Molecular and cellular biology", "1998 Apr", "Kozlowski M, Larose L, Lee F, Le DM, Rottapel R, Siminovitch KA", "protein_xref_pubmed", "9528781", "protein_xref_iptmnet", "P05532" ], [ "P05532-1", "Tyrosine residue 719 of the c-kit receptor is essential for binding of the P85 subunit of phosphatidylinositol (PI) 3-kinase and for c-kit-associated PI 3-kinase activity in COS-1 cells.", "The Journal of biological chemistry", "1994 Feb 25", "Serve H, Hsu YC, Besmer P", "protein_xref_pubmed", "7509796", "protein_xref_iptmnet", "P05532" ], [ "P05622-1", "Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras.", "Proceedings of the National Academy of Sciences of the United States of America", "1994 Jul 19", "Bennett AM, Tang TL, Sugimoto S, Walsh CT, Neel BG", "protein_xref_pubmed", "8041791", "protein_xref_iptmnet", "P05622" ], [ "P05622-1", "Sequence requirements for binding of Src family tyrosine kinases to activated growth factor receptors.", "The Journal of biological chemistry", "1995 Apr 28", "Alonso G, Koegl M, Mazurenko N, Courtneidge SA", "protein_xref_pubmed", "7730365", "protein_xref_iptmnet", "P05622" ], [ "P05622-1", "PSM, a mediator of PDGF-BB-, IGF-I-, and insulin-stimulated mitogenesis.", "Oncogene", "2000 Jan 6", "Riedel H, Yousaf N, Zhao Y, Dai H, Deng Y, Wang J", "protein_xref_pubmed", "10644978", "protein_xref_iptmnet", "P05622" ], [ "P05622-1", "Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.", "Molecular & cellular proteomics : MCP", "2008-09", "Mertins Philipp, Eberl H Christian, Renkawitz J\u00f6rg, Olsen Jesper V, Tremblay Michel L, Mann Matthias, Ullrich Axel, Daub Henrik", "protein_xref_pubmed", "18515860", "protein_xref_iptmnet", "P05622" ], [ "P08101-1", "Protein interactions of Src homology 2 (SH2) domain-containing inositol phosphatase (SHIP): association with Shc displaces SHIP from FcgammaRIIb in B cells.", "Journal of immunology (Baltimore, Md. : 1950)", "1999-02-01", "Tridandapani S, Pradhan M, LaDine J R, Garber S, Anderson C L, Coggeshall K M", "protein_xref_pubmed", "9973396", "protein_xref_iptmnet", "P08101" ], [ "P09581-1", "Identification of a second Grb2 binding site in the v-Fms tyrosine kinase.", "Oncogene", "1997 Sep 25", "Mancini A, Niedenthal R, Joos H, Koch A, Trouliaris S, Niemann H, Tamura T", "protein_xref_pubmed", "9380408", "protein_xref_iptmnet", "P09581" ], [ "P09581-1", "Mona, a novel hematopoietic-specific adaptor interacting with the macrophage colony-stimulating factor receptor, is implicated in monocyte/macrophage development.", "The EMBO journal", "1998-12-15", "Bourette R P, Arnaud S, Myles G M, Blanchet J P, Rohrschneider L R, Mouchiroud G", "protein_xref_pubmed", "9857184", "protein_xref_iptmnet", "P09581" ], [ "P09581-1", "Tyr721 regulates specific binding of the CSF-1 receptor kinase insert to PI 3'-kinase SH2 domains: a model for SH2-mediated receptor-target interactions.", "The EMBO journal", "1992 Apr", "Reedijk M, Liu X, van der Geer P, Letwin K, Waterfield MD, Hunter T, Pawson T", "protein_xref_pubmed", "1314163", "protein_xref_iptmnet", "P09581" ], [ "P09793-1", "Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152).", "Biochemical and biophysical research communications", "1998 Aug 19", "Miyatake S, Nakaseko C, Umemori H, Yamamoto T, Saito T", "protein_xref_pubmed", "9712716", "protein_xref_iptmnet", "P09793" ], [ "P10637-1", "PKA modulates GSK-3beta- and cdk5-catalyzed phosphorylation of tau in site- and kinase-specific manners.", "FEBS letters", "2006 Nov 13", "Liu F, Liang Z, Shi J, Yin D, El-Akkad E, Grundke-Iqbal I, Iqbal K, Gong CX", "protein_xref_pubmed", "17078951", "protein_xref_iptmnet", "P10637" ], [ "P11416-1", "A coordinated phosphorylation cascade initiated by p38MAPK/MSK1 directs RARalpha to target promoters.", "The EMBO journal", "2009 Jan 7", "Bruck N, Vitoux D, Ferry C, Duong V, Bauer A, de The H, Rochette-Egly C", "protein_xref_pubmed", "19078967", "protein_xref_iptmnet", "P11416" ], [ "P13405-1", "RB regulates pancreas development by stabilizing Pdx1.", "The EMBO journal", "2011-04-20", "Kim Yong-Chul, Kim So Yoon, Mellado-Gil Jose Manuel, Yadav Hariom, Neidermyer William, Kamaraju Anil K, Rane Sushil G", "protein_xref_pubmed", "21399612", "protein_xref_iptmnet", "P13405" ], [ "P14753-1", "Tyrosine 425 within the activated erythropoietin receptor binds Syp, reduces the erythropoietin required for Syp tyrosine phosphorylation, and promotes mitogenesis.", "Blood", "1996 Jun 1", "Tauchi T, Damen JE, Toyama K, Feng GS, Broxmeyer HE, Krystal G", "protein_xref_pubmed", "8639815", "protein_xref_iptmnet", "P14753" ], [ "P14753-1", "Proteasomes regulate erythropoietin receptor and signal transducer and activator of transcription 5 (STAT5) activation. Possible involvement of the ubiquitinated Cis protein.", "The Journal of biological chemistry", "1998 Oct 23", "Verdier F, Chretien S, Muller O, Varlet P, Yoshimura A, Gisselbrecht S, Lacombe C, Mayeux P", "protein_xref_pubmed", "9774439", "protein_xref_iptmnet", "P14753" ], [ "P14753-1", "Lyn physically associates with the erythropoietin receptor and may play a role in activation of the Stat5 pathway.", "Blood", "1998 May 15", "Chin H, Arai A, Wakao H, Kamiyama R, Miyasaka N, Miura O", "protein_xref_pubmed", "9573010", "protein_xref_iptmnet", "P14753" ], [ "P18052-1", "The receptor-like protein-tyrosine phosphatase, RPTP alpha, is phosphorylated by protein kinase C on two serines close to the inner face of the plasma membrane.", "The Journal of biological chemistry", "1995 May 5", "Tracy S, van der Geer P, Hunter T", "protein_xref_pubmed", "7537734", "protein_xref_iptmnet", "P18052" ], [ "P18052-1", "The structure of the membrane distal phosphatase domain of RPTPalpha reveals interdomain flexibility and an SH2 domain interaction region.", "Biochemistry", "2003-07-08", "Sonnenburg Erica Dutil, Bilwes Alexandrine, Hunter Tony, Noel Joseph P", "protein_xref_pubmed", "12834342", "protein_xref_iptmnet", "P18052" ], [ "P18052-1", "Phosphorylation of receptor protein-tyrosine phosphatase alpha on Tyr789, a binding site for the SH3-SH2-SH3 adaptor protein GRB-2 in vivo.", "The EMBO journal", "1994 Jul 1", "den Hertog J, Tracy S, Hunter T", "protein_xref_pubmed", "7518772", "protein_xref_iptmnet", "P18052" ], [ "P20444-1", "A Ras activation pathway dependent on Syk phosphorylation of protein kinase C.", "Proceedings of the National Academy of Sciences of the United States of America", "2003 Aug 5", "Kawakami Y, Kitaura J, Yao L, McHenry RW, Kawakami Y, Newton AC, Kang S, Kato RM, Leitges M, Rawlings DJ, Kawakami T", "protein_xref_pubmed", "12881490", "protein_xref_iptmnet", "P20444" ], [ "P23804-1", "Polo-like kinase-1 phosphorylates MDM2 at Ser260 and stimulates MDM2-mediated p53 turnover.", "FEBS letters", "2009 Nov 19", "Dias SS, Hogan C, Ochocka AM, Meek DW", "protein_xref_pubmed", "19833129", "protein_xref_iptmnet", "P23804" ], [ "P26618-1", "Platelet-derived growth factor-mediated signaling through the Shb adaptor protein: effects on cytoskeletal organization.", "Experimental cell research", "2000 Jun 15", "Hooshmand-Rad R, Lu L, Heldin CH, Claesson-Welsh L, Welsh M", "protein_xref_pubmed", "10837138", "protein_xref_iptmnet", "P26618" ], [ "P28867-1", "Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-delta with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-delta.", "Oncogene", "1998-07-02", "Song J S, Swann P G, Szallasi Z, Blank U, Blumberg P M, Rivera J", "protein_xref_pubmed", "9692543", "protein_xref_iptmnet", "P28867" ], [ "P30875-1", "Direct binding of p85 to sst2 somatostatin receptor reveals a novel mechanism for inhibiting PI3K pathway.", "The EMBO journal", "2006 Sep 6", "Bousquet C, Guillermet-Guibert J, Saint-Laurent N, Archer-Lahlou E, Lopez F, Fanjul M, Ferrand A, Fourmy D, Pichereaux C, Monsarrat B, Pradayrol L, Esteve JP, Susini C", "protein_xref_pubmed", "16917505", "protein_xref_iptmnet", "P30875" ], [ "P30999-1", "Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.", "Molecular & cellular proteomics : MCP", "2008-09", "Mertins Philipp, Eberl H Christian, Renkawitz J\u00f6rg, Olsen Jesper V, Tremblay Michel L, Mann Matthias, Ullrich Axel, Daub Henrik", "protein_xref_pubmed", "18515860", "protein_xref_iptmnet", "P30999" ], [ "P31809-1", "The carboxyl-terminal region of biliary glycoprotein controls its tyrosine phosphorylation and association with protein-tyrosine phosphatases SHP-1 and SHP-2 in epithelial cells.", "The Journal of biological chemistry", "1999 Jan 1", "Huber M, Izzi L, Grondin P, Houde C, Kunath T, Veillette A, Beauchemin N", "protein_xref_pubmed", "9867848", "protein_xref_iptmnet", "P31809" ], [ "P34152-3", "Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase.", "Nature", "1994 Dec 22-29", "Schlaepfer DD, Hanks SK, Hunter T, van der Geer P", "protein_xref_pubmed", "7997267", "protein_xref_iptmnet", "P34152" ], [ "P34152-3", "Focal adhesion kinase overexpression enhances ras-dependent integrin signaling to ERK2/mitogen-activated protein kinase through interactions with and activation of c-Src.", "The Journal of biological chemistry", "1997 May 16", "Schlaepfer DD, Hunter T", "protein_xref_pubmed", "9148935", "protein_xref_iptmnet", "P34152" ], [ "P34152-3", "Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases.", "Molecular and cellular biology", "1996 Oct", "Schlaepfer DD, Hunter T", "protein_xref_pubmed", "8816475", "protein_xref_iptmnet", "P34152" ], [ "P35235-2", "Site-specific incorporation of a phosphotyrosine mimetic reveals a role for tyrosine phosphorylation of SHP-2 in cell signaling.", "Molecular cell", "2001 Oct", "Lu W, Gong D, Bar-Sagi D, Cole PA", "protein_xref_pubmed", "11684012", "protein_xref_iptmnet", "P35235" ], [ "P35235-2", "Interleukin (IL)-3 and granulocyte/macrophage colony-stimulating factor, but not IL-4, induce tyrosine phosphorylation, activation, and association of SHPTP2 with Grb2 and phosphatidylinositol 3'-kinase.", "The Journal of biological chemistry", "1994 Sep 23", "Welham MJ, Dechert U, Leslie KB, Jirik F, Schrader JW", "protein_xref_pubmed", "7522233", "protein_xref_iptmnet", "P35235" ], [ "P35235-2", "Analysis of tyrosine phosphorylation-dependent protein-protein interactions in TrkB-mediated intracellular signaling using modified yeast two-hybrid system.", "Journal of biochemistry", "2001 Jul", "Yamada M, Suzuki K, Mizutani M, Asada A, Matozaki T, Ikeuchi T, Koizumi S, Hatanaka H", "protein_xref_pubmed", "11432792", "protein_xref_iptmnet", "P35235" ], [ "P35235-2", "SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130.", "The Journal of biological chemistry", "2003-01-03", "Lehmann Ute, Schmitz Jochen, Weissenbach Manuela, Sobota Radoslaw M, Hortner Michael, Friederichs Kerstin, Behrmann Iris, Tsiaris William, Sasaki Atsuo, Schneider-Mergener Jens, Yoshimura Akihiko, Neel Benjamin G, Heinrich Peter C, Schaper Fred", "protein_xref_pubmed", "12403768", "protein_xref_iptmnet", "P35235" ], [ "P35235-2", "The adaptor function of SHP-2 downstream of the prolactin receptor is required for the recruitment of p29, a substrate of SHP-2.", "Cellular signalling", "2003 Mar", "Minoo P, Chughtai N, Campiglio M, Stein-Gerlach M, Lebrun JJ, Ullrich A, Ali S", "protein_xref_pubmed", "12531430", "protein_xref_iptmnet", "P35235" ], [ "P35235-2", "Multiple in vivo phosphorylated tyrosine phosphatase SHP-2 engages binding to Grb2 via tyrosine 584.", "Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research", "1996 Dec", "Vogel W, Ullrich A", "protein_xref_pubmed", "8959326", "protein_xref_iptmnet", "P35235" ], [ "P35235-2", "Use of the two hybrid system to detect the association of the protein-tyrosine-phosphatase, SHPTP2, with another SH2-containing protein, Grb7.", "Oncogene", "1996 Apr 4", "Keegan K, Cooper JA", "protein_xref_pubmed", "8622870", "protein_xref_iptmnet", "P35235" ], [ "P35918-1", "A single autophosphorylation site on KDR/Flk-1 is essential for VEGF-A-dependent activation of PLC-gamma and DNA synthesis in vascular endothelial cells.", "The EMBO journal", "2001 Jun 1", "Takahashi T, Yamaguchi S, Chida K, Shibuya M", "protein_xref_pubmed", "11387210", "protein_xref_iptmnet", "P35918" ], [ "P35918-1", "The presence of a single tyrosine residue at the carboxyl domain of vascular endothelial growth factor receptor-2/FLK-1 regulates its autophosphorylation and activation of signaling molecules.", "The Journal of biological chemistry", "2002 Jul 26", "Meyer RD, Dayanir V, Majnoun F, Rahimi N", "protein_xref_pubmed", "12023952", "protein_xref_iptmnet", "P35918" ], [ "P39447-1", "Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.", "Molecular & cellular proteomics : MCP", "2008-09", "Mertins Philipp, Eberl H Christian, Renkawitz J\u00f6rg, Olsen Jesper V, Tremblay Michel L, Mann Matthias, Ullrich Axel, Daub Henrik", "protein_xref_pubmed", "18515860", "protein_xref_iptmnet", "P39447" ], [ "P42227-1", "Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB/STAT3 pathway after ischemic stroke in mice.", "Journal of neuroinflammation", "2016-10-10", "Qiu Jing, Yan Zhongjun, Tao Kai, Li Yansong, Li Yuqian, Li Jingchen, Dong Yushu, Feng Dayun, Chen Huisheng", "protein_xref_pubmed", "27724964", "protein_xref_iptmnet", "P42227" ], [ "P42227-1", "Observation of unphosphorylated STAT3 core protein binding to target dsDNA by PEMSA and X-ray crystallography.", "FEBS letters", "2013-04-02", "Nkansah Edwin, Shah Rahi, Collie Gavin W, Parkinson Gary N, Palmer Jonathan, Rahman Khondaker M, Bui Tam T, Drake Alex F, Husby Jarmila, Neidle Stephen, Zinzalla Giovanna, Thurston David E, Wilderspin Andrew F", "protein_xref_pubmed", "23434585", "protein_xref_iptmnet", "P42227" ], [ "P48025-1", "Inhibition of beta 2 integrin receptor and Syk kinase signaling in monocytes by the Src family kinase Fgr.", "Immunity", "2001 Oct", "Vines CM, Potter JW, Xu Y, Geahlen RL, Costello PS, Tybulewicz VL, Lowell CA, Chang PW, Gresham HD, Willman CL", "protein_xref_pubmed", "11672534", "protein_xref_iptmnet", "P48025" ], [ "P48025-1", "Structural basis for the requirement of two phosphotyrosine residues in signaling mediated by Syk tyrosine kinase.", "Journal of molecular biology", "2006-03-10", "Groesch Teresa D, Zhou Fei, Mattila Sampo, Geahlen Robert L, Post Carol Beth", "protein_xref_pubmed", "16410013", "protein_xref_iptmnet", "P48025" ], [ "P48168-1", "Regulation of glycine receptor diffusion properties and gephyrin interactions by protein kinase C.", "The EMBO journal", "2011-08-09", "Specht Christian G, Gr\u00fcnewald Nora, Pascual Olivier, Rostgaard Nina, Schwarz G\u00fcnter, Triller Antoine", "protein_xref_pubmed", "21829170", "protein_xref_iptmnet", "P48168" ], [ "P49817-1", "A phosphotyrosine-dependent protein interaction screen reveals a role for phosphorylation of caveolin-1 on tyrosine 14: recruitment of C-terminal Src kinase.", "The Journal of biological chemistry", "2002-03-15", "Cao Haiming, Courchesne William E, Mastick Cynthia Corley", "protein_xref_pubmed", "11805080", "protein_xref_iptmnet", "P49817" ], [ "P52800-1", "Single phosphorylation of Tyr304 in the cytoplasmic tail of ephrin B2 confers high-affinity and bifunctional binding to both the SH2 domain of Grb4 and the PDZ domain of the PDZ-RGS3 protein.", "European journal of biochemistry", "2004 May", "Su Z, Xu P, Ni F", "protein_xref_pubmed", "15096211", "protein_xref_iptmnet", "P52800" ], [ "P54763-3", "A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases.", "The EMBO journal", "2006-10-04", "Wiesner Silke, Wybenga-Groot Leanne E, Warner Neil, Lin Hong, Pawson Tony, Forman-Kay Julie D, Sicheri Frank", "protein_xref_pubmed", "16977320", "protein_xref_iptmnet", "P54763" ], [ "P55284-1", "Association of Csk to VE-cadherin and inhibition of cell proliferation.", "The EMBO journal", "2005 May 4", "Baumeister U, Funke R, Ebnet K, Vorschmitt H, Koch S, Vestweber D", "protein_xref_pubmed", "15861137", "protein_xref_iptmnet", "P55284" ], [ "P70218-1", "B cell adaptor containing src homology 2 domain (BASH) links B cell receptor signaling to the activation of hematopoietic progenitor kinase 1.", "The Journal of experimental medicine", "2001 Aug 20", "Tsuji S, Okamoto M, Yamada K, Okamoto N, Goitsuka R, Arnold R, Kiefer F, Kitamura D", "protein_xref_pubmed", "11514608", "protein_xref_iptmnet", "P70218" ], [ "P97318-1", "Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons.", "Current biology : CB", "2004 Apr 6", "Ballif BA, Arnaud L, Arthur WT, Guris D, Imamoto A, Cooper JA", "protein_xref_pubmed", "15062102", "protein_xref_iptmnet", "P97318" ], [ "P97465-1", "Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.", "Molecular & cellular proteomics : MCP", "2008-09", "Mertins Philipp, Eberl H Christian, Renkawitz J\u00f6rg, Olsen Jesper V, Tremblay Michel L, Mann Matthias, Ullrich Axel, Daub Henrik", "protein_xref_pubmed", "18515860", "protein_xref_iptmnet", "P97465" ], [ "P98083-1", "Interaction of Shc with Grb2 regulates association of Grb2 with mSOS.", "Molecular and cellular biology", "1995-02", "Ravichandran K S, Lorenz U, Shoelson S E, Burakoff S J", "protein_xref_pubmed", "7529871", "protein_xref_iptmnet", "P98083" ], [ "Q01279-1", "Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.", "Molecular & cellular proteomics : MCP", "2008-09", "Mertins Philipp, Eberl H Christian, Renkawitz J\u00f6rg, Olsen Jesper V, Tremblay Michel L, Mann Matthias, Ullrich Axel, Daub Henrik", "protein_xref_pubmed", "18515860", "protein_xref_iptmnet", "Q01279" ], [ "Q02248-1", "Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling.", "PloS one", "2008", "Piao S, Lee SH, Kim H, Yum S, Stamos JL, Xu Y, Lee SJ, Lee J, Oh S, Han JK, Park BJ, Weis WI, Ha NC", "protein_xref_pubmed", "19107203", "protein_xref_iptmnet", "Q02248" ], [ "Q02858-1", "Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.", "The Journal of biological chemistry", "1999 Oct 22", "Jones N, Master Z, Jones J, Bouchard D, Gunji Y, Sasaki H, Daly R, Alitalo K, Dumont DJ", "protein_xref_pubmed", "10521483", "protein_xref_iptmnet", "Q02858" ], [ "Q02858-1", "Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt.", "Molecular and cellular biology", "1998 Jul", "Kontos CD, Stauffer TP, Yang WP, York JD, Huang L, Blanar MA, Meyer T, Peters KG", "protein_xref_pubmed", "9632797", "protein_xref_iptmnet", "Q02858" ], [ "Q03145-1", "A change in conformational dynamics underlies the activation of Eph receptor tyrosine kinases.", "The EMBO journal", "2006-10-04", "Wiesner Silke, Wybenga-Groot Leanne E, Warner Neil, Lin Hong, Pawson Tony, Forman-Kay Julie D, Sicheri Frank", "protein_xref_pubmed", "16977320", "protein_xref_iptmnet", "Q03145" ], [ "Q06649-1", "Tyrosine phosphorylation of adaptor protein 3BP2 induces T cell receptor-mediated activation of transcription factor.", "Biochemistry", "2005 Mar 15", "Qu X, Kawauchi-Kamata K, Miah SM, Hatani T, Yamamura H, Sada K", "protein_xref_pubmed", "15751964", "protein_xref_iptmnet", "Q06649" ], [ "Q06649-1", "Adaptor protein 3BP2 is a potential ligand of Src homology 2 and 3 domains of Lyn protein-tyrosine kinase.", "The Journal of biological chemistry", "2003 Jul 4", "Maeno K, Sada K, Kyo S, Miah SM, Kawauchi-Kamata K, Qu X, Shi Y, Yamamura H", "protein_xref_pubmed", "12709437", "protein_xref_iptmnet", "Q06649" ], [ "Q06806-1", "The endothelial receptor tyrosine kinase Tie1 activates phosphatidylinositol 3-kinase and Akt to inhibit apoptosis.", "Molecular and cellular biology", "2002 Mar", "Kontos CD, Cha EH, York JD, Peters KG", "protein_xref_pubmed", "11865050", "protein_xref_iptmnet", "Q06806" ], [ "Q60598-1", "Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.", "Molecular & cellular proteomics : MCP", "2008-09", "Mertins Philipp, Eberl H Christian, Renkawitz J\u00f6rg, Olsen Jesper V, Tremblay Michel L, Mann Matthias, Ullrich Axel, Daub Henrik", "protein_xref_pubmed", "18515860", "protein_xref_iptmnet", "Q60598" ], [ "Q60598-1", "Tyrosine phosphorylation controls cortactin binding to two enterohaemorrhagic Escherichia coli effectors: Tir and EspFu/TccP.", "Cellular microbiology", "2007-07", "Cantarelli Vlademir V, Kodama Toshio, Nijstad Niels, Abolghait Said Kamal, Nada Shigeyuki, Okada Masato, Iida Tetsuya, Honda Takeshi", "protein_xref_pubmed", "17451412", "protein_xref_iptmnet", "Q60598" ], [ "Q60838-1", "Identification of a novel Wnt5a-CK1varepsilon-Dvl2-Plk1-mediated primary cilia disassembly pathway.", "The EMBO journal", "2012 May 18", "Lee KH, Johmura Y, Yu LR, Park JE, Gao Y, Bang JK, Zhou M, Veenstra TD, Yeon Kim B, Lee KS", "protein_xref_pubmed", "22609948", "protein_xref_iptmnet", "Q60838" ], [ "Q61037-1", "Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1/TSC2 in C2C12 myotubes.", "The FEBS journal", "2010-05", "Miyazaki Mitsunori, McCarthy John J, Esser Karyn A", "protein_xref_pubmed", "20412061", "protein_xref_iptmnet", "Q61037" ], [ "Q61152-1", "SH2 domain-mediated interaction of inhibitory protein tyrosine kinase Csk with protein tyrosine phosphatase-HSCF.", "Molecular and cellular biology", "2001 Feb", "Wang B, Lemay S, Tsai S, Veillette A", "protein_xref_pubmed", "11158295", "protein_xref_iptmnet", "Q61152" ], [ "Q61851-1", "Interaction of fibroblast growth factor receptor 3 and the adapter protein SH2-B. A role in STAT5 activation.", "The Journal of biological chemistry", "2002-05-03", "Kong Monica, Wang Ching S, Donoghue Daniel J", "protein_xref_pubmed", "11827956", "protein_xref_iptmnet", "Q61851" ], [ "Q62073-1", "The E3 ligase Itch and deubiquitinase Cyld act together to regulate Tak1 and inflammation.", "Nature immunology", "2011-11-06", "Ahmed Neesar, Zeng Minghui, Sinha Indrajit, Polin Lisa, Wei Wei-Zen, Rathinam Chozhavendan, Flavell Richard, Massoumi Ramin, Venuprasad K", "protein_xref_pubmed", "22057290", "protein_xref_iptmnet", "Q62073" ], [ "Q62077-1", "Analysis of leptin signalling in hematopoietic cells using an adapted MAPPIT strategy.", "FEBS letters", "2006-05-29", "Montoye T, Piessevaux J, Lavens D, Wauman J, Catteeuw D, Vandekerckhove J, Lemmens I, Tavernier J", "protein_xref_pubmed", "16698021", "protein_xref_iptmnet", "Q62077" ], [ "Q62077-1", "Investigation of protein-tyrosine phosphatase 1B function by quantitative proteomics.", "Molecular & cellular proteomics : MCP", "2008-09", "Mertins Philipp, Eberl H Christian, Renkawitz J\u00f6rg, Olsen Jesper V, Tremblay Michel L, Mann Matthias, Ullrich Axel, Daub Henrik", "protein_xref_pubmed", "18515860", "protein_xref_iptmnet", "Q62077" ], [ "Q62120-1", "The JAK-binding protein JAB inhibits Janus tyrosine kinase activity through binding in the activation loop.", "The EMBO journal", "1999 Mar 1", "Yasukawa H, Misawa H, Sakamoto H, Masuhara M, Sasaki A, Wakioka T, Ohtsuka S, Imaizumi T, Matsuda T, Ihle JN, Yoshimura A", "protein_xref_pubmed", "10064597", "protein_xref_iptmnet", "Q62120" ], [ "Q62120-1", "The N-terminal SH2 domain of the tyrosine phosphatase, SHP-2, is essential for Jak2-dependent signaling via the angiotensin II type AT1 receptor.", "Cellular signalling", "2007 Mar", "Godeny MD, Sayyah J, VonDerLinden D, Johns M, Ostrov DA, Caldwell-Busby J, Sayeski PP", "protein_xref_pubmed", "17027227", "protein_xref_iptmnet", "Q62120" ], [ "Q62120-1", "Tyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta.", "Molecular and cellular biology", "2004 May", "Kurzer JH, Argetsinger LS, Zhou YJ, Kouadio JL, O'Shea JJ, Carter-Su C", "protein_xref_pubmed", "15121872", "protein_xref_iptmnet", "Q62120" ], [ "Q62120-1", "Structural basis for phosphotyrosine recognition by the Src homology-2 domains of the adapter proteins SH2-B and APS.", "Journal of molecular biology", "2006 Aug 4", "Hu J, Hubbard SR", "protein_xref_pubmed", "16824542", "protein_xref_iptmnet", "Q62120" ], [ "Q62120-1", "Binding of SH2-B family members within a potential negative regulatory region maintains JAK2 in an active state.", "Molecular and cellular biology", "2006-09", "Kurzer Jason H, Saharinen Pipsa, Silvennoinen Olli, Carter-Su Christin", "protein_xref_pubmed", "16914724", "protein_xref_iptmnet", "Q62120" ], [ "Q62137-1", "Tyrosine 813 is a site of JAK2 autophosphorylation critical for activation of JAK2 by SH2-B beta.", "Molecular and cellular biology", "2004 May", "Kurzer JH, Argetsinger LS, Zhou YJ, Kouadio JL, O'Shea JJ, Carter-Su C", "protein_xref_pubmed", "15121872", "protein_xref_iptmnet", "Q62137" ] ] }, "readme": "Name\n - Mouse Proteoform Phosphorylation Citations (iPTMnet)\n\nVersion\n - v-2.3.1\n\nCreated on\n - 2021-06-03T17:31:30.200524\n\nModified on\n - 2023-03-14T16:58:53.981Z\n\nCreated by\n - [jeetvora@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n - \n\nChecksum\n - \n\nExecution Domain\n Scripts\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: mouse_proteoform_phosphorylation_sites_iptmnet.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/mouse_proteoform_phosphorylation_sites_iptmnet.csv\n Output Subdomain\n Name: mouse_proteoform_citations_phosphorylation_sites_iptmnet.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/mouse_proteoform_citations_phosphorylation_sites_iptmnet.csv\n Name: mouse_proteoform_citations_phosphorylation_sites_iptmnet.stat.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.3.1/reviewed/mouse_proteoform_citations_phosphorylation_sites_iptmnet.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"5212\"\n Name: \"title\"\n Description: \"Title of the published article in the journal\"\n Unique Values: \"5707\"\n Name: \"journal_name\"\n Description: \"The name of the journal in which the article is published\"\n Unique Values: \"719\"\n Name: \"publication_date\"\n Description: \"Contains the full date on which the issue of the journal was published. Sourced from MEDLINE/PubMed data element(fields) description.\"\n Unique Values: \"2949\"\n Name: \"authors\"\n Description: \"NA\"\n Unique Values: \"5697\"\n Name: \"xref_key\"\n Description: \"Source key associated to the xref_id\"\n Unique Values: \"1\"\n Name: \"xref_id\"\n Description: \"ID of the X-ref\"\n Unique Values: \"5707\"\n Name: \"src_xref_key\"\n Description: \"Source Xref key\"\n Unique Values: \"1\"\n Name: \"src_xref_id\"\n Description: \"Source X-ref ID\"\n Unique Values: \"5257\"", "downloadurl": "/ln2data/releases/data/v-2.3.1/reviewed/mouse_proteoform_citations_phosphorylation_sites_iptmnet.csv" }