{
    "bcoid": "GLY_000698",
    "title": "Fruitfly UniProtKB Xref Rhea",
    "description": "The Fruitfly UniProtKB Xref Rhea contains fruitfly [taxid:7227] UniProtKB canonical accessions cross-referenced ...",
    "filename": "fruitfly_protein_xref_rhea.csv",
    "filetype": "csv",
    "categories": {
        "species": [
            "Drosophila melanogaster"
        ],
        "molecule": [
            "Protein"
        ],
        "tag": [
            "Rhea cross-references"
        ],
        "file_type": [
            "csv"
        ],
        "status": [
            "Reviewed"
        ],
        "scope": [
            "internal"
        ]
    },
    "minitable": {
        "content": [
            [
                "P40793-1...",
                "protein_xref..."
            ],
            [
                "P40421-1...",
                "protein_xref..."
            ]
        ],
        "headers": [
            "uniprotkb_ca...",
            "xref_key..."
        ],
        "colwidth": [
            "40%",
            "20%"
        ]
    },
    "sampledata": {
        "type": "table",
        "data": [
            [
                {
                    "type": "string",
                    "label": "uniprotkb_canonical_ac"
                },
                {
                    "type": "string",
                    "label": "xref_key"
                },
                {
                    "type": "string",
                    "label": "xref_id"
                },
                {
                    "type": "string",
                    "label": "xref_label"
                }
            ],
            [
                "P40793-1",
                "protein_xref_rhea",
                "19669",
                "GTP + H2O = GDP + H(+) + phosphate"
            ],
            [
                "P40421-1",
                "protein_xref_rhea",
                "20629",
                "H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate"
            ],
            [
                "P40421-1",
                "protein_xref_rhea",
                "47004",
                "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate"
            ],
            [
                "P04388-1",
                "protein_xref_rhea",
                "19669",
                "GTP + H2O = GDP + H(+) + phosphate"
            ],
            [
                "Q27869-1",
                "protein_xref_rhea",
                "12705",
                "[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine"
            ],
            [
                "Q02870-1",
                "protein_xref_rhea",
                "13065",
                "ATP + H2O = ADP + H(+) + phosphate"
            ],
            [
                "Q95R35-1",
                "protein_xref_rhea",
                "28783",
                "H2O + L-cysteinylglycine = glycine + L-cysteine"
            ],
            [
                "Q95R35-1",
                "protein_xref_rhea",
                "60444",
                "an S-substituted L-cysteinylglycine + H2O = an S-substituted L-cysteine + glycine"
            ],
            [
                "Q95R35-1",
                "protein_xref_rhea",
                "62568",
                "H2O + S-benzyl-L-cysteinylglycine = glycine + S-benzyl-L-cysteine"
            ],
            [
                "P17336-1",
                "protein_xref_rhea",
                "20309",
                "2 H2O2 = 2 H2O + O2"
            ],
            [
                "P56079-1",
                "protein_xref_rhea",
                "16229",
                "a 1,2-diacyl-sn-glycero-3-phosphate + CTP + H(+) = a CDP-1,2-diacyl-sn-glycerol + diphosphate"
            ],
            [
                "P48555-1",
                "protein_xref_rhea",
                "19669",
                "GTP + H2O = GDP + H(+) + phosphate"
            ],
            [
                "P03896-1",
                "protein_xref_rhea",
                "29091",
                "a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) + NAD(+)"
            ],
            [
                "A1ZAI5-1",
                "protein_xref_rhea",
                "52716",
                "a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)"
            ],
            [
                "A1ZAI3-1",
                "protein_xref_rhea",
                "52716",
                "a long-chain fatty acyl-CoA + 2 H(+) + 2 NADPH = a long-chain primary fatty alcohol + CoA + 2 NADP(+)"
            ],
            [
                "A1ZAI3-1",
                "protein_xref_rhea",
                "36315",
                "2 H(+) + hexadecanoyl-CoA + 2 NADPH = CoA + hexadecan-1-ol + 2 NADP(+)"
            ],
            [
                "A1ZAI3-1",
                "protein_xref_rhea",
                "36319",
                "2 H(+) + 2 NADPH + octadecanoyl-CoA = CoA + 2 NADP(+) + octadecan-1-ol"
            ],
            [
                "P32870-1",
                "protein_xref_rhea",
                "15389",
                "ATP = 3',5'-cyclic AMP + diphosphate"
            ],
            [
                "M9PJN5-1",
                "protein_xref_rhea",
                "58196",
                "H2O + N(6)-acetyl-L-lysyl-[histone] = acetate + L-lysyl-[histone]"
            ],
            [
                "P07487-1",
                "protein_xref_rhea",
                "10300",
                "D-glyceraldehyde 3-phosphate + NAD(+) + phosphate = (2R)-3-phospho-glyceroyl phosphate + H(+) + NADH"
            ],
            [
                "P27619-1",
                "protein_xref_rhea",
                "19669",
                "GTP + H2O = GDP + H(+) + phosphate"
            ],
            [
                "Q01583-4",
                "protein_xref_rhea",
                "10272",
                "a 1,2-diacyl-sn-glycerol + ATP = a 1,2-diacyl-sn-glycero-3-phosphate + ADP + H(+)"
            ],
            [
                "P13678-1",
                "protein_xref_rhea",
                "17989",
                "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]"
            ],
            [
                "P13678-1",
                "protein_xref_rhea",
                "46608",
                "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]"
            ],
            [
                "Q04499-1",
                "protein_xref_rhea",
                "23784",
                "a quinone + L-proline = (S)-1-pyrroline-5-carboxylate + a quinol + H(+)"
            ],
            [
                "P32870-1",
                "protein_xref_rhea",
                "15389",
                "ATP = 3',5'-cyclic AMP + diphosphate"
            ],
            [
                "Q7JQ32-1",
                "protein_xref_rhea",
                "13665",
                "GTP = 3',5'-cyclic GMP + diphosphate"
            ],
            [
                "A0A0B4LGD3-1",
                "protein_xref_rhea",
                "72427",
                "chloride(in) + K(+)(in) = chloride(out) + K(+)(out)"
            ],
            [
                "Q9W1G0-1",
                "protein_xref_rhea",
                "17053",
                "D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate"
            ],
            [
                "Q9VY42-1",
                "protein_xref_rhea",
                "15093",
                "2-oxoglutarate + L-tyrosine = 3-(4-hydroxyphenyl)pyruvate + L-glutamate"
            ],
            [
                "Q9VY44-1",
                "protein_xref_rhea",
                "67004",
                "a 5'-end triphospho-ribonucleoside in mRNA + H2O = a 5'-end diphospho-ribonucleoside in mRNA + H(+) + phosphate"
            ],
            [
                "Q9VY44-1",
                "protein_xref_rhea",
                "67012",
                "a 5'-end diphospho-ribonucleoside in mRNA + GTP + H(+) = a 5'-end (5'-triphosphoguanosine)-(ribonucleoside) in mRNA + diphosphate"
            ],
            [
                "Q9VE09-1",
                "protein_xref_rhea",
                "17521",
                "ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate"
            ],
            [
                "Q9VCT3-1",
                "protein_xref_rhea",
                "32727",
                "a very-long-chain acyl-CoA + H(+) + malonyl-CoA = a very-long-chain 3-oxoacyl-CoA + CO2 + CoA"
            ],
            [
                "P06603-1",
                "protein_xref_rhea",
                "19669",
                "GTP + H2O = GDP + H(+) + phosphate"
            ],
            [
                "P06606-1",
                "protein_xref_rhea",
                "19669",
                "GTP + H2O = GDP + H(+) + phosphate"
            ],
            [
                "P06604-1",
                "protein_xref_rhea",
                "19669",
                "GTP + H2O = GDP + H(+) + phosphate"
            ],
            [
                "P06605-1",
                "protein_xref_rhea",
                "19669",
                "GTP + H2O = GDP + H(+) + phosphate"
            ],
            [
                "P18475-1",
                "protein_xref_rhea",
                "10596",
                "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]"
            ],
            [
                "Q9VWN3-1",
                "protein_xref_rhea",
                "40523",
                "a quinone + succinate = a quinol + fumarate"
            ],
            [
                "X2JEB8-1",
                "protein_xref_rhea",
                "10684",
                "H2O + O-phospho-L-tyrosyl-[protein] = L-tyrosyl-[protein] + phosphate"
            ],
            [
                "X2JEB8-1",
                "protein_xref_rhea",
                "20629",
                "H2O + O-phospho-L-seryl-[protein] = L-seryl-[protein] + phosphate"
            ],
            [
                "X2JEB8-1",
                "protein_xref_rhea",
                "47004",
                "H2O + O-phospho-L-threonyl-[protein] = L-threonyl-[protein] + phosphate"
            ],
            [
                "P00522-1",
                "protein_xref_rhea",
                "10596",
                "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]"
            ],
            [
                "P00528-1",
                "protein_xref_rhea",
                "10596",
                "ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]"
            ],
            [
                "Q9V9Y8-1",
                "protein_xref_rhea",
                "10748",
                "H(+) + hydrogencarbonate = CO2 + H2O"
            ],
            [
                "Q9VU38-1",
                "protein_xref_rhea",
                "20824",
                "adenosine + ATP = ADP + AMP + H(+)"
            ],
            [
                "Q9VU38-1",
                "protein_xref_rhea",
                "20824",
                "adenosine + ATP = ADP + AMP + H(+)"
            ],
            [
                "Q9VU37-1",
                "protein_xref_rhea",
                "21672",
                "[protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine + S-adenosyl-L-methionine = [protein]-C-terminal S-[(2E,6E)-farnesyl]-L-cysteine methyl ester + S-adenosyl-L-homocysteine"
            ],
            [
                "Q9VSW1-1",
                "protein_xref_rhea",
                "19889",
                "alpha-D-glucose 1-phosphate + H(+) + UTP = diphosphate + UDP-alpha-D-glucose"
            ],
            [
                "P40320-1",
                "protein_xref_rhea",
                "21080",
                "ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine"
            ],
            [
                "Q9VF26-1",
                "protein_xref_rhea",
                "13065",
                "ATP + H2O = ADP + H(+) + phosphate"
            ],
            [
                "Q9VF27-1",
                "protein_xref_rhea",
                "29091",
                "a ubiquinone + 5 H(+)(in) + NADH = a ubiquinol + 4 H(+)(out) + NAD(+)"
            ],
            [
                "Q9VF20-1",
                "protein_xref_rhea",
                "61360",
                "ATP + H2O + pheophorbide a(in) = ADP + H(+) + pheophorbide a(out) + phosphate"
            ],
            [
                "Q9VF20-1",
                "protein_xref_rhea",
                "19261",
                "ATP + H2O + heme b(in) = ADP + H(+) + heme b(out) + phosphate"
            ],
            [
                "Q9VF20-1",
                "protein_xref_rhea",
                "61336",
                "ATP + H2O + protoporphyrin IX(in) = ADP + H(+) + phosphate + protoporphyrin IX(out)"
            ],
            [
                "Q9VF20-1",
                "protein_xref_rhea",
                "66664",
                "ATP + coproporphyrin III(in) + H2O = ADP + coproporphyrin III(out) + H(+) + phosphate"
            ],
            [
                "Q9VF20-1",
                "protein_xref_rhea",
                "66680",
                "ATP + coproporphyrinogen III(in) + H2O = ADP + coproporphyrinogen III(out) + H(+) + phosphate"
            ],
            [
                "Q9VF20-1",
                "protein_xref_rhea",
                "66768",
                "ATP + coproporphyrin I(in) + H2O = ADP + coproporphyrin I(out) + H(+) + phosphate"
            ],
            [
                "Q9VF20-1",
                "protein_xref_rhea",
                "66772",
                "ATP + H2O + uroporphyrin I(in) = ADP + H(+) + phosphate + uroporphyrin I(out)"
            ],
            [
                "Q9VF20-1",
                "protein_xref_rhea",
                "66776",
                "ATP + H2O + uroporphyrin III(in) = ADP + H(+) + phosphate + uroporphyrin III(out)"
            ],
            [
                "Q9VGJ9-1",
                "protein_xref_rhea",
                "21764",
                "heme b + 3 O2 + 3 reduced [NADPH--hemoprotein reductase] = biliverdin IXalpha + CO + Fe(2+) + H(+) + 3 H2O + 3 oxidized [NADPH--hemoprotein reductase]"
            ],
            [
                "Q9W374-1",
                "protein_xref_rhea",
                "18093",
                "5,6-dihydrouracil + NADP(+) = H(+) + NADPH + uracil"
            ],
            [
                "Q9V6L0-1",
                "protein_xref_rhea",
                "60200",
                "2 2-oxoglutarate + N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 2 O2 = 2 CO2 + 2 formaldehyde + N(6)-methyl-L-lysyl(9)-[histone H3] + 2 succinate"
            ],
            [
                "Q9VAP1-1",
                "protein_xref_rhea",
                "23380",
                "N-acetyl-alpha-D-glucosaminyl-diphosphodolichol + UDP-N-acetyl-alpha-D-glucosamine = H(+) + N,N'-diacetylchitobiosyl diphosphodolichol + UDP"
            ],
            [
                "A8DZ26-1",
                "protein_xref_rhea",
                "13065",
                "ATP + H2O = ADP + H(+) + phosphate"
            ],
            [
                "A0A0B4KHF0-1",
                "protein_xref_rhea",
                "11148",
                "4 Fe(2+) + 4 H(+) + O2 = 4 Fe(3+) + 2 H2O"
            ],
            [
                "A1ZBL9-1",
                "protein_xref_rhea",
                "17989",
                "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]"
            ],
            [
                "A1ZBL9-1",
                "protein_xref_rhea",
                "46608",
                "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]"
            ],
            [
                "A0A126GUV7-1",
                "protein_xref_rhea",
                "17989",
                "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]"
            ],
            [
                "A0A126GUV7-1",
                "protein_xref_rhea",
                "46608",
                "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]"
            ],
            [
                "Q95028-1",
                "protein_xref_rhea",
                "23444",
                "(S)-lactate + NAD(+) = H(+) + NADH + pyruvate"
            ],
            [
                "Q0KHV6-1",
                "protein_xref_rhea",
                "17989",
                "ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]"
            ],
            [
                "Q0KHV6-1",
                "protein_xref_rhea",
                "46608",
                "ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]"
            ],
            [
                "Q7K1W4-1",
                "protein_xref_rhea",
                "23900",
                "cis-stilbene oxide + H2O = (1R,2R)-hydrobenzoin"
            ],
            [
                "Q7K1W4-1",
                "protein_xref_rhea",
                "55764",
                "1-(4-methoxyphenyl)-N-methyl-N-[(3-methyloxetan-3-yl)methyl]methanamine + H2O = 2-{[(4-methoxybenzyl)(methyl)amino]methyl}-2-methylpropane-1,3-diol"
            ],
            [
                "Q9VZ64-1",
                "protein_xref_rhea",
                "12556",
                "6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate + H(+)"
            ],
            [
                "A0A4D6K026-1",
                "protein_xref_rhea",
                "13665",
                "GTP = 3',5'-cyclic GMP + diphosphate"
            ],
            [
                "Q9VBK8-1",
                "protein_xref_rhea",
                "20696",
                "2 H(+) + 2 superoxide = H2O2 + O2"
            ],
            [
                "Q9VL52-1",
                "protein_xref_rhea",
                "13065",
                "ATP + H2O = ADP + H(+) + phosphate"
            ],
            [
                "Q9VI85-1",
                "protein_xref_rhea",
                "62432",
                "a uridine in tRNA + S-adenosyl-L-methionine = a 3-[(3S)-3-amino-3-carboxypropyl]uridine in tRNA + H(+) + S-methyl-5'-thioadenosine"
            ],
            [
                "Q9VU79-1",
                "protein_xref_rhea",
                "13665",
                "GTP = 3',5'-cyclic GMP + diphosphate"
            ],
            [
                "A0A0B4LGD3-1",
                "protein_xref_rhea",
                "72427",
                "chloride(in) + K(+)(in) = chloride(out) + K(+)(out)"
            ],
            [
                "Q9W251-1",
                "protein_xref_rhea",
                "36683",
                "hexadecanoyl-CoA + L-cysteinyl-[protein] = CoA + S-hexadecanoyl-L-cysteinyl-[protein]"
            ]
        ]
    },
    "readme": "Name\n   - Fruitfly UniProtKB Xref Rhea\n\nVersion\n   - v-2.2.1\n\nCreated on\n  - 2022-09-06T16:53:49.310443\n\nModified on\n   - 2022-09-26T09:08:12.763780\n\nCreated by\n   - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n   - \n\nChecksum\n   - \n\nUsability Domain\n   - The Fruitfly UniProtKB Xref Rhea contains fruitfly [taxid:7227] UniProtKB canonical accessions cross-referenced to Rhea database accessions/identifiers. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB and GlyGen. \n   - Rhea\n\nDescription Domain\n   Keywords\n   - reactions\n   - Rhea\n   - cross-reference\n\n   Pipeline Steps\n   - Step-1: The script loads the UniProtKB canonical accessions that are cross-referenced to Rhea database accessions/identifiers from the triplestore containing triples from nt file and extracts the data as a csv dataset. \n\nExecution Domain\n   Scripts   - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n   Software Prerequisites\n      Name: Python\n      Version: 2.7.5\n      URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n   Input Subdomain\n      Name: uniprot-proteome-drosophila-melanogaster.nt\n      URI: https:/data.glygen.org/ln2downloads/ebi/2023_10_30/uniprot-proteome-drosophila-melanogaster.nt\n   Output Subdomain\n      Name: fruitfly_protein_xref_rhea.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.2.1/reviewed/fruitfly_protein_xref_rhea.csv\n      Name: fruitfly_protein_xref_rhea.stat.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.2.1/reviewed/fruitfly_protein_xref_rhea.stat.csv\n\nFields\n      Name: \"uniprotkb_canonical_ac\"\n     Description: \"\"\n      Unique Values: \"1226\"\n      Name: \"xref_key\"\n     Description: \"Source key associated to the  xref_id\"\n      Unique Values: \"1\"\n      Name: \"xref_id\"\n     Description: \"ID of the X-ref\"\n      Unique Values: \"934\"\n      Name: \"xref_label\"\n     Description: \"Label/Name associated with x-ref\"\n      Unique Values: \"934\"",
    "downloadurl": "/ln2data/releases/data/v-2.2.1/reviewed/fruitfly_protein_xref_rhea.csv"
}