{ "bcoid": "GLY_000361", "title": "HCV1a Gene Ontology (GO)", "description": "The Hepatitis C virus (genotype 1a, isolate H) Gene Ontology (GO) dataset contains hcv1a [taxid:11108] ...", "filename": "hcv1a_protein_go_annotation.csv", "filetype": "csv", "categories": { "species": [ "Hepatitis c virus (isolate h)" ], "molecule": [ "Protein" ], "tag": [ "Gene Ontology (Go)" ], "file_type": [ "csv" ], "status": [ "Reviewed" ], "scope": [ "internal" ] }, "minitable": { "content": [ [ "P27958-1...", "..." ], [ "P27958-1...", "..." ] ], "headers": [ "uniprotkb_ca...", "gene_symbol..." ], "colwidth": [ "40%", "20%" ] }, "sampledata": { "type": "table", "data": [ [ { "type": "string", "label": "uniprotkb_canonical_ac" }, { "type": "string", "label": "gene_symbol" }, { "type": "string", "label": "go_term_id" }, { "type": "string", "label": "go_term_label" }, { "type": "string", "label": "go_term_category" }, { "type": "string", "label": "eco_id" }, { "type": "string", "label": "pmid" } ], [ "P27958-1", "", "GO_0050689", "negative regulation of defense response to virus by host", "biological_process", "", "" ], [ "P27958-1", "", "GO_0070104", "negative regulation of interleukin-6-mediated signaling pathway", "biological_process", "", "" ], [ "P27958-1", "", "GO_0044164", "host cell cytosol", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0050709", "negative regulation of protein secretion", "biological_process", "", "" ], [ "P27958-1", "", "GO_0097677", "STAT family protein binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_1990254", "keratin filament binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0042025", "host cell nucleus", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0044053", "translocation of peptides or proteins into host cell cytoplasm", "biological_process", "", "" ], [ "P27958-1", "", "GO_1900102", "negative regulation of endoplasmic reticulum unfolded protein response", "biological_process", "", "" ], [ "P27958-1", "", "GO_0005124", "scavenger receptor binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0019082", "viral protein processing", "biological_process", "", "" ], [ "P27958-1", "", "GO_0019054", "modulation by virus of host cellular process", "biological_process", "", "" ], [ "P27958-1", "", "GO_0034136", "negative regulation of toll-like receptor 2 signaling pathway", "biological_process", "", "" ], [ "P27958-1", "", "GO_0003968", "RNA-dependent RNA polymerase activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0000122", "negative regulation of transcription by RNA polymerase II", "biological_process", "", "" ], [ "P27958-1", "", "GO_0003723", "RNA binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0004252", "serine-type endopeptidase activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0005216", "monoatomic ion channel activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0005524", "ATP binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0006508", "proteolysis", "biological_process", "", "" ], [ "P27958-1", "", "GO_0008270", "zinc ion binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0008284", "positive regulation of cell population proliferation", "biological_process", "", "" ], [ "P27958-1", "", "GO_0010628", "positive regulation of gene expression", "biological_process", "", "" ], [ "P27958-1", "", "GO_0017124", "SH3 domain binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0019899", "enzyme binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0042802", "identical protein binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0051259", "protein complex oligomerization", "biological_process", "", "" ], [ "P27958-1", "", "GO_0002674", "negative regulation of acute inflammatory response", "biological_process", "", "" ], [ "P27958-1", "", "GO_0016887", "ATP hydrolysis activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0031072", "heat shock protein binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0032715", "negative regulation of interleukin-6 production", "biological_process", "", "" ], [ "P27958-1", "", "GO_0005198", "structural molecule activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0008134", "transcription factor binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0019900", "kinase binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0051047", "positive regulation of secretion", "biological_process", "", "" ], [ "P27958-1", "", "GO_0033116", "endoplasmic reticulum-Golgi intermediate compartment membrane", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0060548", "negative regulation of cell death", "biological_process", "", "" ], [ "P27958-1", "", "GO_0031267", "small GTPase binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0045727", "positive regulation of translation", "biological_process", "", "" ], [ "P27958-1", "", "GO_0008233", "peptidase activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0019031", "viral envelope", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0010804", "negative regulation of tumor necrosis factor-mediated signaling pathway", "biological_process", "", "" ], [ "P27958-1", "", "GO_0031953", "negative regulation of protein autophosphorylation", "biological_process", "", "" ], [ "P27958-1", "", "GO_0019903", "protein phosphatase binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0017151", "DEAD/H-box RNA helicase binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0033673", "negative regulation of kinase activity", "biological_process", "", "" ], [ "P27958-1", "", "GO_0045862", "positive regulation of proteolysis", "biological_process", "", "" ], [ "P27958-1", "", "GO_0090201", "negative regulation of release of cytochrome c from mitochondria", "biological_process", "", "" ], [ "P27958-1", "", "GO_0002039", "p53 binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0004197", "cysteine-type endopeptidase activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0030889", "negative regulation of B cell proliferation", "biological_process", "", "" ], [ "P27958-1", "", "GO_0032780", "negative regulation of ATP-dependent activity", "biological_process", "", "" ], [ "P27958-1", "", "GO_0042288", "MHC class I protein binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_1903265", "positive regulation of tumor necrosis factor-mediated signaling pathway", "biological_process", "", "" ], [ "P27958-1", "", "GO_1990904", "ribonucleoprotein complex", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0019087", "transformation of host cell by virus", "biological_process", "", "" ], [ "P27958-1", "", "GO_0039502", "suppression by virus of host type I interferon-mediated signaling pathway", "biological_process", "", "" ], [ "P27958-1", "", "GO_0039563", "suppression by virus of host JAK-STAT cascade via inhibition of STAT1 activity", "biological_process", "", "" ], [ "P27958-1", "", "GO_0032467", "positive regulation of cytokinesis", "biological_process", "", "" ], [ "P27958-1", "", "GO_0019013", "viral nucleocapsid", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0019050", "suppression by virus of host apoptotic process", "biological_process", "", "" ], [ "P27958-1", "", "GO_1900118", "negative regulation of execution phase of apoptosis", "biological_process", "", "" ], [ "P27958-1", "", "GO_0060590", "ATPase regulator activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0008236", "serine-type peptidase activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0034144", "negative regulation of toll-like receptor 4 signaling pathway", "biological_process", "", "" ], [ "P27958-1", "", "GO_0039520", "induction by virus of host autophagy", "biological_process", "", "" ], [ "P27958-1", "", "GO_0019056", "modulation by virus of host transcription", "biological_process", "", "" ], [ "P27958-1", "", "GO_0039694", "viral RNA genome replication", "biological_process", "", "" ], [ "P27958-1", "", "GO_0030291", "protein serine/threonine kinase inhibitor activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0003724", "RNA helicase activity", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0044220", "host cell perinuclear region of cytoplasm", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0034156", "negative regulation of toll-like receptor 7 signaling pathway", "biological_process", "", "" ], [ "P27958-1", "", "GO_0034164", "negative regulation of toll-like receptor 9 signaling pathway", "biological_process", "", "" ], [ "P27958-1", "", "GO_0031369", "translation initiation factor binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0048524", "positive regulation of viral process", "biological_process", "", "" ], [ "P27958-1", "", "GO_1903301", "positive regulation of hexokinase activity", "biological_process", "", "" ], [ "P27958-1", "", "GO_0010694", "positive regulation of alkaline phosphatase activity", "biological_process", "", "" ], [ "P27958-1", "", "GO_0035663", "Toll-like receptor 2 binding", "molecular_function", "", "" ], [ "P27958-1", "", "GO_0055036", "virion membrane", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0030430", "host cell cytoplasm", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0020002", "host cell plasma membrane", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0033644", "host cell membrane", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0033647", "host intracellular organelle", "cellular_component", "", "" ], [ "P27958-1", "", "GO_0039545", "suppression by virus of host viral-induced cytoplasmic pattern recognition receptor signaling pathway via inhibition of MAVS activity", "biological_process", "", "" ] ] }, "readme": "Name\n - HCV1a Gene Ontology (GO)\n\nVersion\n - v-2.2.1\n\nCreated on\n - 2020-03-14T15:15:56.229012\n\nModified on\n - 2022-09-26T09:05:27.605977\n\nCreated by\n - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n - Maria Martin [martin@ebi.ac.uk], Preethi Vasudev [pvasudev@ebi.ac.uk]\n\nChecksum\n - \n\nUsability Domain\n - The Hepatitis C virus (genotype 1a, isolate H) Gene Ontology (GO) dataset contains hcv1a [taxid:11108] Gene Ontology Id and name, categories and evidence information for UniProtKB canonical accessions. The dataset is derived from 2019-09 UniProt release. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB and GlyGen\n\nDescription Domain\n Keywords\n - go id\n - go name\n - molecular function\n - biological process\n - cellular component\n - Gene Ontology (GO)\n\n Pipeline Steps\n - Step-1: The script extracts the GO Id, name, category and evidence from the triplestore of NT file and maps it to the UniProtKB canonical sequences.\n\nExecution Domain\n Scripts - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n Software Prerequisites\n Name: Python\n Version: 2.7.5\n URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n Input Subdomain\n Name: uniprot-proteome-hepatitis-c-virus-1a.nt\n URI: https:/data.glygen.org/ln2downloads/ebi/2023_10_30/uniprot-proteome-hepatitis-c-virus-1a.nt\n Output Subdomain\n Name: hcv1a_protein_go_annotation.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.2.1/reviewed/hcv1a_protein_go_annotation.csv\n Name: hcv1a_protein_go_annotation.stat.csv\n URI: https:/data.glygen.org/ln2releases/data/v-2.2.1/reviewed/hcv1a_protein_go_annotation.stat.csv\n\nFields\n Name: \"uniprotkb_canonical_ac\"\n Description: \"\"\n Unique Values: \"1\"\n Name: \"gene_symbol\"\n Description: \"\"Official gene name/symbol assigned to the gene. Human gene names/symbols are approved by the HUGO Gene Nomenclature Committee (HGNC)\"\n Unique Values: \"1\"\n Name: \"go_term_id\"\n Description: \"The Gene Ontology (GO) term unique alphanumeric identifier\"\n Unique Values: \"109\"\n Name: \"go_term_label\"\n Description: \"The Gene Ontology (GO) name that is a word or string of words\"\n Unique Values: \"109\"\n Name: \"go_term_category\"\n Description: \"\"The Gene Ontology (GO) domain to which the term belongs. There are three ontology domain in GO - cellular component\"\n Unique Values: \"3\"\n Name: \"eco_id\"\n Description: \"Evidence & Conclusion Ontology (ECO) identifier\"\n Unique Values: \"1\"\n Name: \"pmid\"\n Description: \"NCBI PubMed database Identifier\"\n Unique Values: \"1\"", "downloadurl": "/ln2data/releases/data/v-2.2.1/reviewed/hcv1a_protein_go_annotation.csv" }