{
    "bcoid": "GLY_000126",
    "title": "Mouse UniProtKB Xref Reactome",
    "description": "TheMouse UniProtKB Xref Reactome contains mouse [taxid:10090] UniProtKB canonical accessions cross-referenced ...",
    "filename": "mouse_protein_xref_reactome.csv",
    "filetype": "csv",
    "categories": {
        "species": [
            "Mus musculus"
        ],
        "molecule": [
            "Protein"
        ],
        "tag": [
            "Reactome cross-references"
        ],
        "file_type": [
            "csv"
        ],
        "status": [
            "Reviewed"
        ],
        "scope": [
            "internal"
        ]
    },
    "minitable": {
        "content": [
            [
                "B2RXV4-1...",
                "protein_xref..."
            ],
            [
                "B2RXV4-1...",
                "protein_xref..."
            ]
        ],
        "headers": [
            "uniprotkb_ca...",
            "xref_key..."
        ],
        "colwidth": [
            "40%",
            "20%"
        ]
    },
    "sampledata": {
        "type": "table",
        "data": [
            [
                {
                    "type": "string",
                    "label": "uniprotkb_canonical_ac"
                },
                {
                    "type": "string",
                    "label": "xref_key"
                },
                {
                    "type": "string",
                    "label": "xref_id"
                },
                {
                    "type": "string",
                    "label": "xref_label"
                }
            ],
            [
                "B2RXV4-1",
                "protein_xref_reactome",
                "R-MMU-917937",
                "Iron uptake and transport"
            ],
            [
                "B2RXV4-1",
                "protein_xref_reactome",
                "R-MMU-189451",
                "Heme biosynthesis"
            ],
            [
                "B2RXV4-1",
                "protein_xref_reactome",
                "R-MMU-189451",
                "Heme biosynthesis"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-141444",
                "Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-141444",
                "Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-141444",
                "Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-141430",
                "Inactivation of APC/C via direct inhibition of the APC/C complex"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-141444",
                "Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-2500257",
                "Resolution of Sister Chromatid Cohesion"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-2500257",
                "Resolution of Sister Chromatid Cohesion"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-2467813",
                "Separation of Sister Chromatids"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-2467813",
                "Separation of Sister Chromatids"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-2500257",
                "Resolution of Sister Chromatid Cohesion"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-2500257",
                "Resolution of Sister Chromatid Cohesion"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-68877",
                "Mitotic Prometaphase"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-5663220",
                "RHO GTPases Activate Formins"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-5663220",
                "RHO GTPases Activate Formins"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-5663220",
                "RHO GTPases Activate Formins"
            ],
            [
                "E9Q3P4-1",
                "protein_xref_reactome",
                "R-MMU-9648025",
                "EML4 and NUDC in mitotic spindle formation"
            ],
            [
                "P03899-1",
                "protein_xref_reactome",
                "R-MMU-6799198",
                "Complex I biogenesis"
            ],
            [
                "P03899-1",
                "protein_xref_reactome",
                "R-MMU-6799198",
                "Complex I biogenesis"
            ],
            [
                "P03899-1",
                "protein_xref_reactome",
                "R-MMU-6799198",
                "Complex I biogenesis"
            ],
            [
                "P03899-1",
                "protein_xref_reactome",
                "R-MMU-6799198",
                "Complex I biogenesis"
            ],
            [
                "P03899-1",
                "protein_xref_reactome",
                "R-MMU-611105",
                "Respiratory electron transport"
            ],
            [
                "O35153-1",
                "protein_xref_reactome",
                "R-MMU-6807878",
                "COPI-mediated anterograde transport"
            ],
            [
                "O35153-1",
                "protein_xref_reactome",
                "R-MMU-6807878",
                "COPI-mediated anterograde transport"
            ],
            [
                "O35153-1",
                "protein_xref_reactome",
                "R-MMU-6807878",
                "COPI-mediated anterograde transport"
            ],
            [
                "O35153-1",
                "protein_xref_reactome",
                "R-MMU-6807878",
                "COPI-mediated anterograde transport"
            ],
            [
                "O35153-1",
                "protein_xref_reactome",
                "R-MMU-6811438",
                "Intra-Golgi traffic"
            ],
            [
                "O35153-1",
                "protein_xref_reactome",
                "R-MMU-6811438",
                "Intra-Golgi traffic"
            ],
            [
                "O35153-1",
                "protein_xref_reactome",
                "R-MMU-6811438",
                "Intra-Golgi traffic"
            ],
            [
                "P03893-1",
                "protein_xref_reactome",
                "R-MMU-6799198",
                "Complex I biogenesis"
            ],
            [
                "P03893-1",
                "protein_xref_reactome",
                "R-MMU-6799198",
                "Complex I biogenesis"
            ],
            [
                "P03893-1",
                "protein_xref_reactome",
                "R-MMU-6799198",
                "Complex I biogenesis"
            ],
            [
                "P03893-1",
                "protein_xref_reactome",
                "R-MMU-6799198",
                "Complex I biogenesis"
            ],
            [
                "P03893-1",
                "protein_xref_reactome",
                "R-MMU-611105",
                "Respiratory electron transport"
            ],
            [
                "Q9QYH9-1",
                "protein_xref_reactome",
                "R-MMU-5668541",
                "TNFR2 non-canonical NF-kB pathway"
            ],
            [
                "Q9QYH9-1",
                "protein_xref_reactome",
                "R-MMU-5668541",
                "TNFR2 non-canonical NF-kB pathway"
            ],
            [
                "Q9QYH9-1",
                "protein_xref_reactome",
                "R-MMU-5668541",
                "TNFR2 non-canonical NF-kB pathway"
            ],
            [
                "Q9QYH9-1",
                "protein_xref_reactome",
                "R-MMU-5668541",
                "TNFR2 non-canonical NF-kB pathway"
            ],
            [
                "Q9QYH9-1",
                "protein_xref_reactome",
                "R-MMU-5676594",
                "TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway"
            ],
            [
                "Q9QYH9-1",
                "protein_xref_reactome",
                "R-MMU-5676594",
                "TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway"
            ],
            [
                "P52479-1",
                "protein_xref_reactome",
                "R-MMU-5656169",
                "Termination of translesion DNA synthesis"
            ],
            [
                "P52479-1",
                "protein_xref_reactome",
                "R-MMU-5656169",
                "Termination of translesion DNA synthesis"
            ],
            [
                "P52479-1",
                "protein_xref_reactome",
                "R-MMU-5689880",
                "Ub-specific processing proteases"
            ],
            [
                "P52479-1",
                "protein_xref_reactome",
                "R-MMU-5689880",
                "Ub-specific processing proteases"
            ],
            [
                "P52479-1",
                "protein_xref_reactome",
                "R-MMU-5689880",
                "Ub-specific processing proteases"
            ],
            [
                "Q9QYH6-1",
                "protein_xref_reactome",
                "R-MMU-9768919",
                "NPAS4 regulates expression of target genes"
            ],
            [
                "P70414-1",
                "protein_xref_reactome",
                "R-MMU-418359",
                "Reduction of cytosolic Ca++ levels"
            ],
            [
                "P70414-1",
                "protein_xref_reactome",
                "R-MMU-5578775",
                "Ion homeostasis"
            ],
            [
                "P70414-1",
                "protein_xref_reactome",
                "R-MMU-425561",
                "Sodium/Calcium exchangers"
            ],
            [
                "P70419-1",
                "protein_xref_reactome",
                "R-MMU-913709",
                "O-linked glycosylation of mucins"
            ],
            [
                "P70419-1",
                "protein_xref_reactome",
                "R-MMU-190372",
                "FGFR3c ligand binding and activation"
            ],
            [
                "Q9EP78-1",
                "protein_xref_reactome",
                "R-MMU-2022870",
                "Chondroitin sulfate biosynthesis"
            ],
            [
                "Q9EP73-1",
                "protein_xref_reactome",
                "R-MMU-389948",
                "PD-1 signaling"
            ],
            [
                "Q9EP73-1",
                "protein_xref_reactome",
                "R-MMU-389948",
                "PD-1 signaling"
            ],
            [
                "Q9EP73-1",
                "protein_xref_reactome",
                "R-MMU-389948",
                "PD-1 signaling"
            ],
            [
                "Q9EP73-1",
                "protein_xref_reactome",
                "R-MMU-389948",
                "PD-1 signaling"
            ],
            [
                "Q9EP75-1",
                "protein_xref_reactome",
                "R-MMU-211979",
                "Eicosanoids"
            ],
            [
                "Q9EP75-1",
                "protein_xref_reactome",
                "R-MMU-211979",
                "Eicosanoids"
            ],
            [
                "Q9EP75-1",
                "protein_xref_reactome",
                "R-MMU-2142691",
                "Synthesis of Leukotrienes (LT) and Eoxins (EX)"
            ],
            [
                "Q9EP75-1",
                "protein_xref_reactome",
                "R-MMU-2142691",
                "Synthesis of Leukotrienes (LT) and Eoxins (EX)"
            ],
            [
                "Q9EP75-1",
                "protein_xref_reactome",
                "R-MMU-2142691",
                "Synthesis of Leukotrienes (LT) and Eoxins (EX)"
            ],
            [
                "O08911-1",
                "protein_xref_reactome",
                "R-MMU-168638",
                "NOD1/2 Signaling Pathway"
            ],
            [
                "O08911-1",
                "protein_xref_reactome",
                "R-MMU-4420097",
                "VEGFA-VEGFR2 Pathway"
            ],
            [
                "O08911-1",
                "protein_xref_reactome",
                "R-MMU-525793",
                "Myogenesis"
            ],
            [
                "O08911-1",
                "protein_xref_reactome",
                "R-MMU-525793",
                "Myogenesis"
            ],
            [
                "O08911-1",
                "protein_xref_reactome",
                "R-MMU-376172",
                "DSCAM interactions"
            ],
            [
                "O08911-1",
                "protein_xref_reactome",
                "R-MMU-5675221",
                "Negative regulation of MAPK pathway"
            ],
            [
                "O08911-1",
                "protein_xref_reactome",
                "R-MMU-5675221",
                "Negative regulation of MAPK pathway"
            ],
            [
                "O08911-1",
                "protein_xref_reactome",
                "R-MMU-5675221",
                "Negative regulation of MAPK pathway"
            ],
            [
                "O08912-1",
                "protein_xref_reactome",
                "R-MMU-6811436",
                "COPI-independent Golgi-to-ER retrograde traffic"
            ],
            [
                "O08912-1",
                "protein_xref_reactome",
                "R-MMU-6811436",
                "COPI-independent Golgi-to-ER retrograde traffic"
            ],
            [
                "O08912-1",
                "protein_xref_reactome",
                "R-MMU-6811436",
                "COPI-independent Golgi-to-ER retrograde traffic"
            ],
            [
                "O08912-1",
                "protein_xref_reactome",
                "R-MMU-913709",
                "O-linked glycosylation of mucins"
            ],
            [
                "O08915-1",
                "protein_xref_reactome",
                "R-MMU-8937144",
                "Aryl hydrocarbon receptor signalling"
            ],
            [
                "O08915-1",
                "protein_xref_reactome",
                "R-MMU-8937144",
                "Aryl hydrocarbon receptor signalling"
            ],
            [
                "O08915-1",
                "protein_xref_reactome",
                "R-MMU-8937144",
                "Aryl hydrocarbon receptor signalling"
            ],
            [
                "O08914-1",
                "protein_xref_reactome",
                "R-MMU-2142753",
                "Arachidonic acid metabolism"
            ],
            [
                "O08917-1",
                "protein_xref_reactome",
                "R-MMU-5213460",
                "RIPK1-mediated regulated necrosis"
            ],
            [
                "O08917-1",
                "protein_xref_reactome",
                "R-MMU-8849932",
                "Synaptic adhesion-like molecules"
            ],
            [
                "O08917-1",
                "protein_xref_reactome",
                "R-MMU-8980692",
                "RHOA GTPase cycle"
            ],
            [
                "O08917-1",
                "protein_xref_reactome",
                "R-MMU-9013026",
                "RHOB GTPase cycle"
            ],
            [
                "O08917-1",
                "protein_xref_reactome",
                "R-MMU-9013106",
                "RHOC GTPase cycle"
            ]
        ]
    },
    "readme": "Name\n   - Mouse UniProtKB Xref Reactome\n\nVersion\n   - v-2.2.1\n\nCreated on\n  - 2019-03-15T16:16:23.633025\n\nModified on\n   - 2022-09-26T08:56:48.476514\n\nCreated by\n   - Jeet Vora [jeetvora@gwu.edu], Robel Kahsay [rykahsay@gwu.edu], Karina Martinez [karinamartinez@gwu.edu], Jingyue Wu [jingyue.wu@email.gwu.edu]\n\nAuthors\n   - Maria Martin [martin@ebi.ac.uk], Preethi Vasudev [pvasudev@ebi.ac.uk]\n\nChecksum\n   - \n\nUsability Domain\n   - TheMouse UniProtKB Xref Reactome contains mouse [taxid:10090] UniProtKB canonical accessions cross-referenced to Reactome database accessions/identifiers.  The dataset is derived from 2019-09 UniProtKB release. If you use this dataset please provide proper attribution to EMBL-EBI-UniProtKB and GlyGen\n   - REACTOME is an open-source, open access, manually curated and peer-reviewed pathway database.\n\nDescription Domain\n   Keywords\n   - pathways\n   - reactions\n   - REACTOME\n   - cross-reference\n\n   Pipeline Steps\n   - Step-1: The script loads the UniProtKB canonical accessions that are cross-referenced to REACTOME database accessions/identifiers from the triplestore containing triples from nt file and extracts the data as a csv dataset. \n\nExecution Domain\n   Scripts   - https://github.com/glygener/glygen-backend-integration/blob/master/dataset-maker/make-protein-dataset.py\n\n\n   Software Prerequisites\n      Name: Python\n      Version: 2.7.5\n      URI: https://www.python.org/download/releases/2.7.5/\n\nI/O Domain\n   Input Subdomain\n      Name: uniprot-proteome-mus-musculus.nt\n      URI: https:/data.glygen.org/ln2downloads/ebi/2023_10_30/uniprot-proteome-mus-musculus.nt\n   Output Subdomain\n      Name: mouse_protein_xref_reactome.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.2.1/reviewed/mouse_protein_xref_reactome.csv\n      Name: mouse_protein_xref_reactome.stat.csv\n      URI: https:/data.glygen.org/ln2releases/data/v-2.2.1/reviewed/mouse_protein_xref_reactome.stat.csv\n\nFields\n      Name: \"uniprotkb_canonical_ac\"\n     Description: \"\"\n      Unique Values: \"9058\"\n      Name: \"xref_key\"\n     Description: \"Source key associated to the  xref_id\"\n      Unique Values: \"1\"\n      Name: \"xref_id\"\n     Description: \"ID of the X-ref\"\n      Unique Values: \"1373\"\n      Name: \"xref_label\"\n     Description: \"Label/Name associated with x-ref\"\n      Unique Values: \"1373\"",
    "downloadurl": "/ln2data/releases/data/v-2.2.1/reviewed/mouse_protein_xref_reactome.csv"
}