{
    "assessed_biomarker_entity": "Sialylated tumor-related antigen (sTRA)",
    "assessed_entity_type": "glycan",
    "components": {
        "protein": [],
        "glycan": [
            {
                "accession": "G78959US",
                "evidence": [
                    {
                        "id": "GLY_000737",
                        "database": "GlyGen",
                        "url": "https://data.glygen.org/GLY_000737"
                    },
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                        "id": "33093149",
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                        "url": "https://glygen.org/publication/PubMed/33093149"
                    }
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            }
        ]
    },
    "instances": [
        {
            "best_biomarker_type": "predictive",
            "status": "increased sTRA level",
            "notes": "",
            "literature_evidence": "Furthermore, a blood-plasma test for the sTRA glycan identified the PDACs that showed rapid relapse following neoadjuvant chemotherapy. This research demonstrates the use of the sTRA glycan to identify the PDAC cases that are highly resistant to chemotherapy. [PMID:33093149]",
            "loinc_code": "",
            "tissue": {
                "name": "blood",
                "namespace": "UBERON",
                "id": "0000178",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178"
            },
            "disease": {
                "disease_id": "DOID:1793",
                "recommended_name": {
                    "id": "DOID:1793",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:1793",
                    "name": "pancreatic cancer",
                    "description": "An endocrine gland cancer located_in the pancreas."
                },
                "synonyms": [
                    {
                        "id": "DOID:1793",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "Ca body of pancreas",
                        "description": ""
                    },
                    {
                        "id": "DOID:1793",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "Ca head of pancreas",
                        "description": ""
                    },
                    {
                        "id": "DOID:1793",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "Ca tail of pancreas",
                        "description": ""
                    },
                    {
                        "id": "DOID:1793",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "malignant neoplasm of body of pancreas",
                        "description": ""
                    },
                    {
                        "id": "DOID:1793",
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                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "malignant neoplasm of head of pancreas",
                        "description": ""
                    },
                    {
                        "id": "DOID:1793",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "malignant neoplasm of tail of pancreas",
                        "description": ""
                    },
                    {
                        "id": "DOID:1793",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "pancreas neoplasm",
                        "description": ""
                    },
                    {
                        "id": "DOID:1793",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "pancreatic neoplasm",
                        "description": ""
                    },
                    {
                        "id": "DOID:1793",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:1793",
                        "name": "pancreatic tumor",
                        "description": ""
                    }
                ]
            },
            "evidence": [
                {
                    "id": "GLY_000737",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_000737"
                },
                {
                    "id": "33093149",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/33093149"
                }
            ]
        }
    ],
    "publication": [
        {
            "title": "Detection of Chemotherapy-resistant Pancreatic Cancer Using a Glycan Biomarker, sTRA.",
            "journal": "Clinical cancer research : an official journal of the American Association for Cancer Research",
            "authors": "Gao C, Wisniewski L, Liu Y, Staal B, Beddows I, Plenker D, Aldakkak M, Hall J, Barnett D, Gouda MK, Allen P, Drake R, Zureikat A, Huang Y, Evans D, Singhi A, Brand RE, Tuveson DA, Tsai S, Haab BB",
            "date": "2021",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "33093149",
                    "url": "https://glygen.org/publication/PubMed/33093149"
                }
            ],
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                    "id": "GLY_000737",
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                    "url": "https://data.glygen.org/GLY_000737"
                }
            ]
        }
    ],
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            "database": "GlyGen",
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        },
        {
            "id": "33093149",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/33093149"
        }
    ],
    "biomarker_id": "A0414",
    "aclist": [
        "G78959US"
    ],
    "crossref": [],
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