{
    "assessed_biomarker_entity": "Apolipoprotein C-I (APOC1)",
    "assessed_entity_type": "protein",
    "components": {
        "protein": [
            {
                "accession": "P02654-1",
                "name": "Apolipoprotein C-I",
                "evidence": [
                    {
                        "id": "GLY_000625",
                        "database": "GlyGen",
                        "url": "https://data.glygen.org/GLY_000625"
                    },
                    {
                        "id": "31555694",
                        "database": "PubMed",
                        "url": "https://glygen.org/publication/PubMed/31555694"
                    }
                ]
            }
        ],
        "glycan": []
    },
    "instances": [
        {
            "best_biomarker_type": "prognostic",
            "status": "increased APOC1 level",
            "notes": "Also a diagnostic biomarker",
            "literature_evidence": "It was firstly found that concentration of APOC1 in serum was significantly higher in GC than that in control. Expression of APOC1 protein was also higher in GC than that in adjacent issues of GC and normal tissues using tissues array by immunohistochemistry. [PMID:31555694]",
            "loinc_code": "",
            "tissue": {
                "name": "stomach",
                "namespace": "UBERON",
                "id": "0000945",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000945"
            },
            "disease": {
                "disease_id": "DOID:10534",
                "recommended_name": {
                    "id": "DOID:10534",
                    "resource": "Disease Ontology",
                    "url": "http://disease-ontology.org/term/DOID:10534",
                    "name": "stomach cancer",
                    "description": "A gastrointestinal system cancer that is located_in the stomach."
                },
                "synonyms": [
                    {
                        "id": "DOID:10534",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:10534",
                        "name": "gastric cancer",
                        "description": ""
                    },
                    {
                        "id": "DOID:10534",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:10534",
                        "name": "gastric neoplasm",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "gastric cancer",
                        "description": "A primary or metastatic malignant neoplasm involving the stomach."
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "gastric neoplasm",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "Ca lesser curvature - stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "cancer of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "gastric cancer",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "gastric cancer risk after h. pylori infection",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "gastric cancer, somatic",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant gastric neoplasm",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant gastric tumor",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant neoplasm of lesser curve of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant neoplasm of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant neoplasm of the stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant stomach neoplasm",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant tumor of body of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant tumor of greater curve of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant tumor of lesser curve of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant tumor of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant tumor of the stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "stomach cancer",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "Ca body - stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "ca greater curvature of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "malignant neoplasm of body of stomach",
                        "description": ""
                    },
                    {
                        "id": "MONDO:0001056",
                        "resource": "MONDO",
                        "url": "https://monarchinitiative.org/disease/MONDO:0001056",
                        "name": "gastric cancer, intestinal",
                        "description": ""
                    },
                    {
                        "id": "MIM:613659",
                        "resource": "MIM",
                        "url": "https://www.omim.org/entry/613659",
                        "name": "Gastric cancer",
                        "description": "Gastric cancer"
                    }
                ]
            },
            "evidence": [
                {
                    "id": "GLY_000625",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_000625"
                },
                {
                    "id": "31555694",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/31555694"
                }
            ]
        }
    ],
    "publication": [
        {
            "title": "Apolipoprotein C1 (APOC1) as a novel diagnostic and prognostic biomarker for gastric cancer.",
            "journal": "Annals of translational medicine",
            "authors": "Yi J, Ren L, Wu J, Li W, Zheng X, Du G, Wang J",
            "date": "2019",
            "reference": [
                {
                    "type": "PubMed",
                    "id": "31555694",
                    "url": "https://glygen.org/publication/PubMed/31555694"
                }
            ],
            "evidence": [
                {
                    "id": "GLY_000625",
                    "database": "GlyGen",
                    "url": "https://data.glygen.org/GLY_000625"
                }
            ]
        }
    ],
    "evidence": [
        {
            "id": "GLY_000625",
            "database": "GlyGen",
            "url": "https://data.glygen.org/GLY_000625"
        },
        {
            "id": "31555694",
            "database": "PubMed",
            "url": "https://glygen.org/publication/PubMed/31555694"
        }
    ],
    "biomarker_id": "A0378",
    "aclist": [
        "P02654-1"
    ],
    "crossref": [],
    "section_stats": [
        {
            "table_id": "instances",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "best_biomarker_type",
                "status",
                "notes",
                "literature_evidence",
                "loinc_code",
                "tissue.name",
                "tissue.namespace",
                "tissue.id",
                "tissue.url",
                "disease.disease_id"
            ]
        },
        {
            "table_id": "components",
            "table_stats": [
                {
                    "field": "total",
                    "count": 2
                }
            ],
            "sort_fields": []
        },
        {
            "table_id": "publication",
            "table_stats": [
                {
                    "field": "total",
                    "count": 1
                }
            ],
            "sort_fields": [
                "title",
                "journal",
                "authors",
                "date"
            ]
        }
    ]
}