{
    "assessed_biomarker_entity": "Stromal cell-derived factor 1 (CXCL12)",
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            "literature_evidence": "Immunohistochemistry revealed positive CXCR4 and CXCL12 expression in 48 (61 %) and 62 (78 %) patients, respectively. The MIB-1 proliferation index was markedly higher in ESCC with a positive expression of CXCR4 or CXCL12. [PMID:27439769]",
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            "title": "CXCL12 expression promotes esophageal squamous cell carcinoma proliferation and worsens the prognosis.",
            "journal": "BMC cancer",
            "authors": "Uchi Y, Takeuchi H, Matsuda S, Saikawa Y, Kawakubo H, Wada N, Takahashi T, Nakamura R, Fukuda K, Omori T, Kitagawa Y",
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