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    "assessed_biomarker_entity": "Dublin-Boston score (IL-6 to IL-10)",
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                        "url": "https://data.glygen.org/GLY_000625"
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                    },
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        ],
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        {
            "best_biomarker_type": "prognostic",
            "status": "increased IL-6 to IL-10 score",
            "notes": "UPKB:P05231|UPKB:P22301",
            "literature_evidence": "The Dublin-Boston score uses the change between two IL-6:IL-10 ratio measurements taken 4 days apart to guide clinical decision-making by identifying hospitalized patients at risk of impending poor outcome, and is applicable to patients both in the ICU and on the ward. The score, and the change in IL-6:IL-10 from which it is derived, significantly outperform the predictive capabilities of IL-6 alone. [PMID:33039714]",
            "loinc_code": "",
            "tissue": {
                "name": "blood",
                "namespace": "UBERON",
                "id": "0000178",
                "url": "http://purl.obolibrary.org/obo/UBERON_0000178"
            },
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                "disease_id": "DOID:0080600",
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                    "url": "http://disease-ontology.org/term/DOID:0080600",
                    "name": "COVID-19",
                    "description": "A Coronavirus infection that is characterized by fever, cough and shortness of breath and that has_material_basis_in SARS-CoV-2."
                },
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                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "2019 Novel Coronavirus (2019-nCoV)",
                        "description": ""
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                    },
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "Wuhan seafood market pneumonia virus infection",
                        "description": ""
                    },
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "COVID19",
                        "description": ""
                    },
                    {
                        "id": "DOID:0080600",
                        "resource": "Disease Ontology",
                        "url": "http://disease-ontology.org/term/DOID:0080600",
                        "name": "SARS-CoV-2 infection",
                        "description": ""
                    }
                ]
            },
            "evidence": [
                {
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                    "url": "https://data.glygen.org/GLY_000625"
                },
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                    "id": "33039714",
                    "database": "PubMed",
                    "url": "https://glygen.org/publication/PubMed/33039714"
                }
            ]
        }
    ],
    "publication": [
        {
            "title": "A linear prognostic score based on the ratio of interleukin-6 to interleukin-10 predicts outcomes in COVID-19.",
            "journal": "EBioMedicine",
            "authors": "McElvaney Oliver J, Hobbs Brian D, Qiao Dandi, McElvaney Ois\u00edn F, Moll Matthew, McEvoy Natalie L, Clarke Jennifer, O'Connor Eoin, Walsh Se\u00e1n, Cho Michael H, Curley Gerard F, McElvaney Noel G",
            "date": "2020-11",
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                }
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    ],
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