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The clinical course is variable even within families. The disease is caused by loss of function of the gene MPI (15q24.1)." }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG-Ib", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "carbohydrate deficient glycoprotein syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital 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The clinical course is variable even within families. The disease is caused by loss of function of the gene MPI (15q24.1)." }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG-Ib", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "carbohydrate deficient glycoprotein syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital 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"MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": 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hypoalbuminaemia, life-threatening intestinal bleeding of diffuse origin, protein C and S deficiency, low anti-thrombine III levels and has_material_basis_in compound heterozygous mutation in the gene encoding mannosephosphate isomerase on chromosome 15q24." }, "synonyms": [ { "id": "DOID:0080554", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080554", "name": "congenital disorder of glycosylation 1b", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-congenital disorder of glycosylation", "description": "MPI-CDG is a form of congenital disorders of N-linked glycosylation, characterized by cyclic vomiting, profound hypoglycemia, failure to thrive, liver fibrosis, gastrointestinal complications (protein-losing enteropathy with hypoalbuminaemia, life-threatening intestinal bleeding of diffuse origin), and thrombotic events (protein C and S deficiency, low anti-thrombine III levels), whereas neurological development and cognitive capacity is usually normal. The clinical course is variable even within families. The disease is caused by loss of function of the gene MPI (15q24.1)." }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG-Ib", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "carbohydrate deficient glycoprotein syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital 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enteropathy with hypoalbuminaemia, life-threatening intestinal bleeding of diffuse origin, protein C and S deficiency, low anti-thrombine III levels and has_material_basis_in compound heterozygous mutation in the gene encoding mannosephosphate isomerase on chromosome 15q24." }, "synonyms": [ { "id": "DOID:0080554", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080554", "name": "congenital disorder of glycosylation 1b", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-congenital disorder of glycosylation", "description": "MPI-CDG is a form of congenital disorders of N-linked glycosylation, characterized by cyclic vomiting, profound hypoglycemia, failure to thrive, liver fibrosis, gastrointestinal complications (protein-losing enteropathy with hypoalbuminaemia, life-threatening intestinal bleeding of diffuse origin), and thrombotic events (protein C and S deficiency, low anti-thrombine III levels), whereas neurological development and cognitive capacity is usually normal. The clinical course is variable even within families. The disease is caused by loss of function of the gene MPI (15q24.1)." }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG-Ib", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "carbohydrate deficient glycoprotein syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital 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co-inhibitory therapy with mannose for oral squamous cell carcinoma.", "journal": "Medical oncology (Northwood, London, England)", "date": "2021", "authors": "Yao Y, Liu W, Li J, Zhou M, Qu C, Wang K", "reference": { "type": "PubMed", "id": "34313879", "url": "https://pubmed.ncbi.nlm.nih.gov/34313879" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P34949-1", "protein_name": "Mannose-6-phosphate isomerase", "gene_name": "MPI", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P34949", "url": "https://www.uniprot.org/uniprotkb/P34949" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34313879", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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{ "uniprot_canonical_ac": "P19367-1", "protein_name": "Hexokinase-1", "gene_name": "HK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P34949", "url": "https://www.uniprot.org/uniprotkb/P34949" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9119384", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "HPCX2", "description": "" }, { "id": "MONDO:0010405", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010405", "name": "prostate cancer, hereditary, X-linked 2", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the RNASEL gene." }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "RNASEL familial prostate cancer", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "HPC3", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, hereditary, type 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "prostate cancer, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012094", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012094", "name": "HPC4", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "prostate cancer, hereditary, type 5", "description": "" }, { "id": "MONDO:0012244", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012244", "name": "HPC5", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] }, { "disease_id": "DOID:0070339", "recommended_name": { "id": "DOID:0070339", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070339", "name": "cerebellar hyplasia/atrophy, epilepsy, and global developmental delay", "description": "A syndrome with a cerebellar malformation as a major feature characterized by cerebellar hypoplasia, bilateral retinal pigmentary changes, intellectual disability that can range from mild to moderate and pronounced language development delay. It presents with early developmental delay, central and peripheral non-progressive visual impairment or asymptomatic retinal changes, hypotonia, non-progressive ataxia and nystagmus." }, "synonyms": [ { "id": "MONDO:0008939", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008939", "name": "isolated cerebellar hypoplasia/agenesis", "description": "Hypoplasia of the cerebellum that is associated with inherited metabolic disorders and neurodegenerative disorders. Signs and symptoms include mental and developmental delays, walking and balance difficulties, floppy muscle tone, and seizures." }, { "id": "MONDO:0008939", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008939", "name": "Cerebellar Agenesis", "description": "" }, { "id": "MONDO:0008939", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008939", "name": "Chiari 4 malformation", "description": "" }, { "id": "MONDO:0008939", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008939", "name": "Chiari IV malformation", "description": "" }, { "id": "MONDO:0008939", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008939", "name": "cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay", "description": "" }, { "id": "MONDO:0008939", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008939", "name": "congenital cerebellar Hypoplasia", "description": "" }, { "id": "MONDO:0008939", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008939", "name": "near total absence of cerebellum", "description": "" }, { "id": "MONDO:0008939", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008939", "name": "subtotal absence of cerebellum", "description": "" }, { "id": "MIM:213000", "resource": "MIM", "url": "https://www.omim.org/entry/213000", "name": "Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay", "description": "Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070339" }, { "id": "0070339", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070339" } ] }, { "disease_id": "DOID:0050570", "recommended_name": { "id": "DOID:0050570", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050570", "name": "congenital disorder of glycosylation type I", "description": "A congenital disorder of glycosylation characterized by under-glycosylated serum glycoproteins." }, "synonyms": [ { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-congenital disorder of glycosylation", "description": "The most frequent form of congenital disorder of N-glycosylation and is characterized by cerebellar dysfunction, abnormal fat distribution, inverted nipples, strabismus and hypotonia. 3 forms of PMM2-CDG can be distinguished: the infantile multisystem type, late-infantile and childhood ataxia-intellectual disability type (3-10 yrs old), and the adult stable disability type. Infants usually develop ataxia, psychomotor delay and extraneurological manifestations including failure to thrive, enteropathy, hepatic dysfunction, coagulation abnormalities and cardiac and renal involvement. The phenotype is however highly variable and ranges from infants who die in the first year of life to mildly involved adults." }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG 1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG syndrome type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG-IA", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-CDG", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-congenital disorder of glycosylation", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate deficient glycoprotein syndrome type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation type 1a", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "phosphomannomutase 2 deficiency", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-CDG (CDG-Ia)", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome type 1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome type 1A (formerly)", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome, type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation, type Ia", "description": "" }, { "id": "MIM:212065", "resource": "MIM", "url": "https://www.omim.org/entry/212065", "name": "Congenital disorder of glycosylation 1A", "description": "Congenital disorder of glycosylation 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050570" } ] }, { "disease_id": "DOID:0080552", "recommended_name": { "id": "DOID:0080552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080552", "name": "congenital disorder of glycosylation Ia", "description": "A congenital disorder of glycosylation I that is characterized by a severe encephalopathy with axial hypotonia, abnormal eye movement, pronounced psychomotor retardation, peripheral neuropathy, cerebellar hypoplasia, and retinitis pigmentosa and has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding phosphomannomutase-2 on chromosome 16p13." }, "synonyms": [ { "id": "DOID:0080552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080552", "name": "PMM2-congenital disorder of glycosylation", "description": "" }, { "id": "DOID:0080552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080552", "name": "congenital disorder of glycosylation 1a", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-congenital disorder of glycosylation", "description": "The most frequent form of congenital disorder of N-glycosylation and is characterized by cerebellar dysfunction, abnormal fat distribution, inverted nipples, strabismus and hypotonia. 3 forms of PMM2-CDG can be distinguished: the infantile multisystem type, late-infantile and childhood ataxia-intellectual disability type (3-10 yrs old), and the adult stable disability type. Infants usually develop ataxia, psychomotor delay and extraneurological manifestations including failure to thrive, enteropathy, hepatic dysfunction, coagulation abnormalities and cardiac and renal involvement. 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frequent form of congenital disorder of N-glycosylation and is characterized by cerebellar dysfunction, abnormal fat distribution, inverted nipples, strabismus and hypotonia. 3 forms of PMM2-CDG can be distinguished: the infantile multisystem type, late-infantile and childhood ataxia-intellectual disability type (3-10 yrs old), and the adult stable disability type. Infants usually develop ataxia, psychomotor delay and extraneurological manifestations including failure to thrive, enteropathy, hepatic dysfunction, coagulation abnormalities and cardiac and renal involvement. The phenotype is however highly variable and ranges from infants who die in the first year of life to mildly involved adults." }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG 1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG syndrome type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG-IA", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-CDG", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-congenital disorder of glycosylation", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate deficient glycoprotein syndrome type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation type 1a", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "phosphomannomutase 2 deficiency", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-CDG (CDG-Ia)", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome type 1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome type 1A (formerly)", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome, type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation, type Ia", "description": "" }, { "id": "MIM:212065", "resource": "MIM", "url": "https://www.omim.org/entry/212065", "name": "Congenital disorder of glycosylation 1A", "description": "Congenital disorder of glycosylation 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050570", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050570" } ] }, { "disease_id": "DOID:0080552", "recommended_name": { "id": "DOID:0080552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080552", "name": "congenital disorder of glycosylation Ia", "description": "A congenital disorder of glycosylation I that is characterized by a severe encephalopathy with axial hypotonia, abnormal eye movement, pronounced psychomotor retardation, peripheral neuropathy, cerebellar hypoplasia, and retinitis pigmentosa and has_material_basis_in homozygous or compound heterozygous mutation in the gene encoding phosphomannomutase-2 on chromosome 16p13." }, "synonyms": [ { "id": "DOID:0080552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080552", "name": "PMM2-congenital disorder of glycosylation", "description": "" }, { "id": "DOID:0080552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080552", "name": "congenital disorder of glycosylation 1a", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-congenital disorder of glycosylation", "description": "The most frequent form of congenital disorder of N-glycosylation and is characterized by cerebellar dysfunction, abnormal fat distribution, inverted nipples, strabismus and hypotonia. 3 forms of PMM2-CDG can be distinguished: the infantile multisystem type, late-infantile and childhood ataxia-intellectual disability type (3-10 yrs old), and the adult stable disability type. Infants usually develop ataxia, psychomotor delay and extraneurological manifestations including failure to thrive, enteropathy, hepatic dysfunction, coagulation abnormalities and cardiac and renal involvement. The phenotype is however highly variable and ranges from infants who die in the first year of life to mildly involved adults." }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG 1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG syndrome type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG-IA", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "CDG1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-CDG", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-congenital disorder of glycosylation", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate deficient glycoprotein syndrome type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation type 1a", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "phosphomannomutase 2 deficiency", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "PMM2-CDG (CDG-Ia)", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome type 1A", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome type 1A (formerly)", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "carbohydrate-deficient glycoprotein syndrome, type Ia", "description": "" }, { "id": "MONDO:0008907", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008907", "name": "congenital disorder of glycosylation, type Ia", "description": "" }, { "id": "MIM:212065", "resource": "MIM", "url": "https://www.omim.org/entry/212065", "name": "Congenital disorder of glycosylation 1A", "description": "Congenital disorder of glycosylation 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080552" } ] } ], "keywords": [ "ebi", "germline", "disease" ], "filter_code": "001000000000000000000.00000000000000.000000000001000000.00001.10.000.000", "uniprot_canonical_ac": "O15305-1" } ], "record_id": "pubmed.9140401", "abstract": "", "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Carbohydrate-deficient glycoprotein syndrome type Ib. Phosphomannose isomerase deficiency and mannose therapy.", "journal": "The Journal of clinical investigation", "date": "1998", "authors": "Niehues R, Hasilik M, Alton G, Korner C, Schiebe-Sukumar M, Koch HG, Zimmer KP, Wu R, Harms E, Reiter K, von Figura K, Freeze HH, Harms HK, Marquardt T", "reference": { "type": "PubMed", "id": "9525984", "url": "https://pubmed.ncbi.nlm.nih.gov/9525984" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P34949-1", "protein_name": "Mannose-6-phosphate isomerase", "gene_name": "MPI", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P34949", "url": "https://www.uniprot.org/uniprotkb/P34949" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "snv": [ { "evidence": [ { "id": "P34949", "database": "BioMuta", "url": "https://hivelab.biochemistry.gwu.edu/biomuta/proteinview/P34949" }, { "id": "rs104894489", "database": "dbSNP", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs104894489" }, { "id": "rs104894489", "database": "ExAC", "url": "https://www.ncbi.nlm.nih.gov/SNP/snp_ref.cgi?type=rs&rs=rs104894489" }, { "id": "rs104894489", "database": "TOPMed", "url": "https://www.ncbi.nlm.nih.gov/snp/rs104894489#frequency_tab" }, { "id": "rs104894489", "database": "gnomAD", "url": "http://gnomad.broadinstitute.org/awesome?query=rs104894489" }, { "id": "10980531", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/10980531" }, { "id": "9525984", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9525984" }, { "id": "rs104894489", "database": "COSMIC", "url": "https://www.ensembl.org/homo_sapiens/Variation/Explore?v=rs104894489" } ], "glycoeffect": [], "start_pos": 219, "end_pos": 219, "subjects_tested": "3601", "subjects_positive": "1", "frequency": "0.0", "sequence_org": "R", "sequence_mut": "Q", "comment": "Somatic mutation passed 1 filters: protein-of-interest(glycogene, carbohydrate synthesis and metabolism/nucleotide synthesis).", "chr_id": "15", "chr_pos": "74893306", "ref_nt": "G", "alt_nt": "A", "minor_allelic_frequency": "", "site_lbl": "R219", "disease": [ { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "CRC", "description": "" }, { "id": "MIM:114500", "resource": "MIM", "url": "https://www.omim.org/entry/114500", "name": "Colorectal cancer", "description": "Colorectal cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ] }, { "disease_id": "DOID:0080554", "recommended_name": { "id": "DOID:0080554", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080554", "name": "congenital disorder of glycosylation Ib", "description": "A congenital disorder of glycosylation I that is characterized by protein-losing enteropathy, cyclic vomiting, profound hypoglycemia, failure to thrive, liver fibrosis, protein-losing enteropathy with hypoalbuminaemia, life-threatening intestinal bleeding of diffuse origin, protein C and S deficiency, low anti-thrombine III levels and has_material_basis_in compound heterozygous mutation in the gene encoding mannosephosphate isomerase on chromosome 15q24." }, "synonyms": [ { "id": "DOID:0080554", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080554", "name": "congenital disorder of glycosylation 1b", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-congenital disorder of glycosylation", "description": "MPI-CDG is a form of congenital disorders of N-linked glycosylation, characterized by cyclic vomiting, profound hypoglycemia, failure to thrive, liver fibrosis, gastrointestinal complications (protein-losing enteropathy with hypoalbuminaemia, life-threatening intestinal bleeding of diffuse origin), and thrombotic events (protein C and S deficiency, low anti-thrombine III levels), whereas neurological development and cognitive capacity is usually normal. The clinical course is variable even within families. The disease is caused by loss of function of the gene MPI (15q24.1)." }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG-Ib", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "carbohydrate deficient glycoprotein syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital disorder of glycosylation type 1b", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital disorder of glycosylation type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "phosphomannose isomerase deficiency", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG 1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG gastrointestinal type", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG (CDG-Ib)", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", 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"https://www.omim.org/entry/602579" }, { "id": "MPI", "database": "Genomics England", "url": "https://panelapp.genomicsengland.co.uk/panels/25/gene/MPI/#!details" }, { "id": "4351", "database": "GlyCosmos", "url": "https://glycosmos.org/glycogenes/show/4351#disease" }, { "id": "0080554", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080554" } ] } ], "keywords": [ "biomuta", "somatic", "cancer", "disease", "ebi" ], "filter_code": "010000000000000000000.00000000000000.000000000001000000.00001.11.000.000", "uniprot_canonical_ac": "P34949-1" } ], "record_id": "pubmed.9525984", "abstract": "", "glycosylation": [], "mutagenesis": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": 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disorder of glycosylation I that is characterized by protein-losing enteropathy, cyclic vomiting, profound hypoglycemia, failure to thrive, liver fibrosis, protein-losing enteropathy with hypoalbuminaemia, life-threatening intestinal bleeding of diffuse origin, protein C and S deficiency, low anti-thrombine III levels and has_material_basis_in compound heterozygous mutation in the gene encoding mannosephosphate isomerase on chromosome 15q24." }, "synonyms": [ { "id": "DOID:0080554", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080554", "name": "congenital disorder of glycosylation 1b", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-congenital disorder of glycosylation", "description": "MPI-CDG is a form of congenital disorders of N-linked glycosylation, characterized by cyclic vomiting, profound hypoglycemia, failure to thrive, liver fibrosis, 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The clinical course is variable even within families. The disease is caused by loss of function of the gene MPI (15q24.1)." }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG-Ib", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "carbohydrate deficient glycoprotein syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital 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The clinical course is variable even within families. The disease is caused by loss of function of the gene MPI (15q24.1)." }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG-Ib", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "carbohydrate deficient glycoprotein syndrome type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital disorder of glycosylation type 1b", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital disorder of glycosylation type IB", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "phosphomannose isomerase deficiency", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG 1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "CDG gastrointestinal type", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "MPI-CDG (CDG-Ib)", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "SLSJ syndrome", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "Saguenay Lac Saint Jean syndrome", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "carbohydrate-deficient glycoprotein syndrome type 1B", "description": "" }, { "id": "MONDO:0011257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257", "name": "congenital disorder of glycosylation, type IB", "description": "" }, { "id": "MIM:602579", "resource": "MIM", "url": "https://www.omim.org/entry/602579", "name": "Congenital disorder of glycosylation 1B", "description": "Congenital disorder of glycosylation 1B" } ], "unlinked_id_list": [], "evidence": [ { "id": "0011257", "database": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011257" }, { "id": "602579", "database": "MIM", "url": 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Struct. Biol.", "date": "1993", "authors": "Schauer T M, Nesper M, Kehl M, Lottspeich F, M\u00fcller-Taubenberger A, Gerisch G, Baumeister W", "reference": { "type": "PubMed", "id": "8130037", "url": "https://pubmed.ncbi.nlm.nih.gov/8130037" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54BC8-1", "protein_name": "Proteasome subunit beta type-5", "gene_name": "psmB5", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GJ6-1", "protein_name": "Proteasome subunit beta type-6", "gene_name": "psmB6", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "P34119-1", "protein_name": "Proteasome subunit alpha type-4", "gene_name": "psmA4", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "P34120-1", "protein_name": "Proteasome subunit alpha type-7", "gene_name": "psmA7", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54BC8", "url": "https://www.uniprot.org/uniprotkb/Q54BC8" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.8130037", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tyrosine phosphorylation-independent nuclear translocation of a dictyostelium STAT in response to DIF signaling.", "journal": "Molecular cell", "date": "2001-04", "authors": "Fukuzawa M, Araki T, Adrian I, Williams J G", "reference": { "type": "PubMed", "id": "11336701", "url": "https://pubmed.ncbi.nlm.nih.gov/11336701" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54BD4-1", "protein_name": "Signal transducer and activator of transcription C", "gene_name": "dstC", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54BD4", "url": "https://www.uniprot.org/uniprotkb/Q54BD4" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "mutagenesis": [ { "start_pos": 924, "end_pos": 924, "sequence_org": "Y", "sequence_mut": "F", "comment": "Loss of activity. Has no effect on DIF-induced translocation to the nucleus.", "evidence": [ { "database": "UniProtKB", "id": "Q54BD4", "url": "https://www.uniprot.org/uniprotkb/Q54BD4" }, { "database": "PubMed", "id": "11336701", "url": "https://pubmed.ncbi.nlm.nih.gov/11336701" } ], "uniprot_canonical_ac": "Q54BD4-1" } ], "phosphorylation": [ { "start_pos": 924, "end_pos": 924, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q54BD4", "url": "https://www.uniprot.org/uniprotkb/Q54BD4" }, { "database": "PubMed", "id": "11336701", "url": "https://pubmed.ncbi.nlm.nih.gov/11336701" } ], "site_lbl": "Tyr924", "uniprot_canonical_ac": "Q54BD4-1" } ], "record_id": "pubmed.11336701", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Dictyostelium prestalk cell inducer DIF regulates nuclear accumulation of a STAT protein by controlling its rate of export from the nucleus.", "journal": "Development (Cambridge, England)", "date": "2003-02", "authors": "Fukuzawa Masashi, Abe Tomoaki, Williams Jeffrey G", "reference": { "type": "PubMed", "id": "12506009", "url": 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Cell", "date": "2004", "authors": "Coukell Barrie, Li Yi, Moniakis John, Cameron Anne", "reference": { "type": "PubMed", "id": "14871937", "url": "https://pubmed.ncbi.nlm.nih.gov/14871937" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54BF5-1", "protein_name": "Calcium up-regulated protein D", "gene_name": "cupD", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z203-1", "protein_name": "Calcium up-regulated protein B", "gene_name": "cupB", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FW5-1", "protein_name": "Calcium up-regulated protein A", "gene_name": "cupA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z1I0-1", "protein_name": "Calcium up-regulated protein F", "gene_name": "cupF", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z1Z9-1", "protein_name": "Calcium up-regulated protein G", "gene_name": "cupG", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7Z202-1", "protein_name": 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the United States of America", "date": "2005-02-22", "authors": "Zhang Haiyu, G\u00f3mez-Garc\u00eda Mar\u00eda R, Brown Michael R W, Kornberg Arthur", "reference": { "type": "PubMed", "id": "15701689", "url": "https://pubmed.ncbi.nlm.nih.gov/15701689" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54BM7-1", "protein_name": "Polyphosphate kinase", "gene_name": "ppkA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54BM7", "url": "https://www.uniprot.org/uniprotkb/Q54BM7" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.15701689", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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Seminary Emily R, Hill R Blake, Link Brian A, Ebert Allison D, Scaglione K Matthew", "reference": { "type": "PubMed", "id": "30029002", "url": "https://pubmed.ncbi.nlm.nih.gov/30029002" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54BX3-1", "protein_name": "serine-rich chaperone protein 1", "gene_name": "hssl63", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54BX3", "url": "https://www.uniprot.org/uniprotkb/Q54BX3" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "mutagenesis": [ { "start_pos": 2, "end_pos": 35, "sequence_org": "TILSTFTSFSNPPKLNKSSFSSSTGSSLSMGSNS", "sequence_mut": "AILAAFAAFANPPKLNKAAFAAAAGAALAMGANA", "comment": "In ST1; does not affect ability to suppress aggregation of proteins with long polyglutamine (polyQ) tracts.", "evidence": [ { 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Microbiol.", "date": "2006", "authors": "Farbrother Patrick, Wagner Carina, Na Jianbo, Tunggal Budi, Morio Takahiro, Urushihara Hideko, Tanaka Yoshimasa, Schleicher Michael, Steinert Michael, Eichinger Ludwig", "reference": { "type": "PubMed", "id": "16469056", "url": "https://pubmed.ncbi.nlm.nih.gov/16469056" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54C27-1", "protein_name": "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "gene_name": "ost1", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QQ0-1", "protein_name": "Inosine-5'-monophosphate dehydrogenase", "gene_name": "impdh", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86CR8-1", "protein_name": "Autophagy-related protein 8", "gene_name": "atg8", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6TMJ3-1", "protein_name": "SrfA-induced gene J protein", "gene_name": "sigJ", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A transcriptional profile of multicellular development in Dictyostelium discoideum.", "journal": "Development", "date": "2002", "authors": "Van Driessche Nancy, Shaw Chad, Katoh Mariko, Morio Takahiro, Sucgang Richard, Ibarra Miroslava, Kuwayama Hidekazu, Saito Tamao, Urushihara Hideko, Maeda Mineko, Takeuchi Ikuo, Ochiai Hiroshi, Eaton William, Tollett Jeffrey, Halter John, Kuspa Adam, Tanaka Yoshimasa, Shaulsky Gad", "reference": { "type": "PubMed", "id": "11923193", "url": "https://pubmed.ncbi.nlm.nih.gov/11923193" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54CK6-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "gene_name": "vti1A", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RF4-1", "protein_name": "Calcium-binding protein 4a", "gene_name": "cbpD1", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9GPM4-1", "protein_name": "Phosphoglycerate kinase", "gene_name": "pgkA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9U7C9-1", "protein_name": "Nucleomorphin", "gene_name": "numA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "P13773-1", "protein_name": "Cyclic AMP receptor 1", "gene_name": "carA-1; carA-2", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "P54638-1", "protein_name": "Acetylornithine deacetylase", "gene_name": "argE", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q27564-1", "protein_name": "Thymidine kinase 1", "gene_name": "thyB", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "P02599-1", "protein_name": "Calmodulin", "gene_name": "calA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54CK6", "url": "https://www.uniprot.org/uniprotkb/Q54CK6" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.11923193", 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"authors": "Bogdanovic Aleksandra, Bennett Nelly, Kieffer Sylvie, Louwagie Mathilde, Morio Takahiro, Garin J\u00e9r\u00f4me, Satre Michel, Bruckert Franz", "reference": { "type": "PubMed", "id": "12175335", "url": "https://pubmed.ncbi.nlm.nih.gov/12175335" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54CK6-1", "protein_name": "Vesicle transport through interaction with t-SNAREs homolog 1A", "gene_name": "vti1A", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54JY7-1", "protein_name": "Syntaxin-7A", "gene_name": "syn7A", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NP6-1", "protein_name": "Alpha-soluble NSF attachment protein", "gene_name": "snpA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NW7-1", "protein_name": "Vesicle-associated membrane protein 7A", "gene_name": "vamp7A", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q553P5-1", "protein_name": "Syntaxin-8A", "gene_name": "syn8A", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q75JI3-1", "protein_name": "Vesicle-fusing ATPase", "gene_name": "nsfA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9U9R7-1", "protein_name": "Gamma-soluble NSF attachment protein", "gene_name": "snpC", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54CK6", "url": "https://www.uniprot.org/uniprotkb/Q54CK6" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.12175335", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.", "journal": "Molecular biology of the cell", "date": "2005-10", "authors": "Lee Susan, Comer Frank I, Sasaki Atsuo, McLeod Ian X, Duong Yung, Okumura Koichi, Yates John R, Parent Carole A, Firtel Richard A", "reference": { "type": "PubMed", "id": "16079174", "url": "https://pubmed.ncbi.nlm.nih.gov/16079174" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54D08-1", "protein_name": "Protein LST8 homolog", "gene_name": "lst8", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86C65-1", "protein_name": "Serine/threonine-protein kinase tor", "gene_name": "tor", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "O77203-1", "protein_name": "Protein pianissimo A", "gene_name": "piaA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y0C9-1", "protein_name": "Ras-interacting protein RIP3", "gene_name": "ripA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BR7-1", "protein_name": "Protein raptor homolog", "gene_name": "raptor", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54D08", "url": "https://www.uniprot.org/uniprotkb/Q54D08" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "mutagenesis": [ { "start_pos": 680, "end_pos": 680, "sequence_org": "K", "sequence_mut": "E", "comment": "Loss of interaction with rasG-GTP; when associated with arg-681.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0C9", "url": "https://www.uniprot.org/uniprotkb/Q9Y0C9" }, { "database": "PubMed", "id": "16079174", "url": "https://pubmed.ncbi.nlm.nih.gov/16079174" } ], "uniprot_canonical_ac": "Q9Y0C9-1" }, { "start_pos": 681, "end_pos": 681, "sequence_org": "R", "sequence_mut": "E", "comment": "Loss of interaction with rasG-GTP; when associated with Lys-680.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y0C9", "url": "https://www.uniprot.org/uniprotkb/Q9Y0C9" }, { "database": "PubMed", "id": "16079174", "url": "https://pubmed.ncbi.nlm.nih.gov/16079174" } ], "uniprot_canonical_ac": "Q9Y0C9-1" } ], "record_id": "pubmed.16079174", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "uniprot_canonical_ac", 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification and characterization of two flavohemoglobin genes in Dictyostelium discoideum.", "journal": "Cell structure and function", "date": "2000-02", "authors": "Iijima M, Shimizu H, Tanaka Y, Urushihara H", "reference": { "type": "PubMed", "id": "10791894", "url": "https://pubmed.ncbi.nlm.nih.gov/10791894" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54D73-1", "protein_name": "Flavohemoprotein B", "gene_name": "fhbB", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9UAG7-1", "protein_name": "Flavohemoprotein A", "gene_name": "fhbA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54D73", "url": "https://www.uniprot.org/uniprotkb/Q54D73" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.10791894", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Trishanku, a novel regulator of cell-type stability and morphogenesis in Dictyostelium discoideum.", "journal": "Differentiation; research in biological diversity", "date": "2006-12", "authors": "Jaiswal Jyoti K, Mujumdar Nameeta, Macwilliams Harry K, Nanjundiah Vidyanand", "reference": { "type": "PubMed", "id": "17177856", "url": "https://pubmed.ncbi.nlm.nih.gov/17177856" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54D84-1", "protein_name": "Trishanku", "gene_name": "triA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54D84", "url": "https://www.uniprot.org/uniprotkb/Q54D84" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.17177856", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The trishanku gene and terminal morphogenesis in Dictyostelium discoideum.", "journal": "Evolution & development", "date": "2009", "authors": "Mujumdar Nameeta, Inouye Kei, Nanjundiah Vidyanand", "reference": { "type": "PubMed", "id": "19878291", "url": "https://pubmed.ncbi.nlm.nih.gov/19878291" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54D84-1", "protein_name": "Trishanku", "gene_name": "triA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54D84", "url": "https://www.uniprot.org/uniprotkb/Q54D84" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.19878291", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Purification and characterization of developmentally regulated AMP deaminase from Dictyostelium discoideum.", "journal": "Differentiation; research in biological diversity", "date": "1991-04", "authors": "Malliaros D P, Kozwich D L, Jahngen E G", "reference": { "type": "PubMed", "id": "1916064", "url": "https://pubmed.ncbi.nlm.nih.gov/1916064" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54DD0-1", "protein_name": "AMP deaminase", "gene_name": "amdA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54DD0", "url": "https://www.uniprot.org/uniprotkb/Q54DD0" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.1916064", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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Cell", "date": "2005", "authors": "Yumura Shigehiko, Yoshida Masashi, Betapudi Venkaiah, Licate Lucila S, Iwadate Yoshiaki, Nagasaki Akira, Uyeda Taro Q P, Egelhoff Thomas T", "reference": { "type": "PubMed", "id": "15987738", "url": "https://pubmed.ncbi.nlm.nih.gov/15987738" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54DK4-1", "protein_name": "Alpha-protein kinase 1", "gene_name": "ak1", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SF9-1", "protein_name": "Myosin heavy chain kinase D", "gene_name": "mhkD", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8MY12-1", "protein_name": "Myosin heavy chain kinase C", "gene_name": "mhkC", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54DK4", "url": "https://www.uniprot.org/uniprotkb/Q54DK4" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", 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Cell Sci.", "date": "1996", "authors": "Liu T, Clarke M", "reference": { "type": "PubMed", "id": "8743951", "url": "https://pubmed.ncbi.nlm.nih.gov/8743951" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54E04-1", "protein_name": "Vacuolar proton translocating ATPase 100 kDa subunit", "gene_name": "vatM", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54E04", "url": "https://www.uniprot.org/uniprotkb/Q54E04" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.8743951", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The ENTH and C-terminal domains of Dictyostelium epsin cooperate to regulate the dynamic interaction with clathrin-coated pits.", "journal": "Journal of cell science", "date": "2008-10-15", "authors": "Brady Rebecca J, Wen Yujia, O'Halloran Theresa J", "reference": { "type": "PubMed", "id": "18827012", "url": "https://pubmed.ncbi.nlm.nih.gov/18827012" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54EH1-1", "protein_name": "Epsin", "gene_name": "epnA", "tax_name": "Social 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"https://pubmed.ncbi.nlm.nih.gov/16819464" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54ER9-1", "protein_name": "Basic-leucine zipper transcription factor B", "gene_name": "dimB", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54ER9", "url": "https://www.uniprot.org/uniprotkb/Q54ER9" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.16819464", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": 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"common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.19002378", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { 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"journal": "Int. J. Parasitol.", "date": "2004", "authors": "Huang Jinling, Mullapudi Nandita, Sicheritz-Ponten Thomas, Kissinger Jessica C", "reference": { "type": "PubMed", "id": "15003488", "url": "https://pubmed.ncbi.nlm.nih.gov/15003488" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54EW8-1", "protein_name": "Dihydrolipoyl dehydrogenase, mitochondrial", "gene_name": "lpd", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q6RYT0-1", "protein_name": "Fructose-1,6-bisphosphatase", "gene_name": "fbp", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54EW8", "url": "https://www.uniprot.org/uniprotkb/Q54EW8" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.15003488", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Characterization of the Ste20-like kinase Krs1 of Dictyostelium discoideum.", "journal": "Eur. J. Cell Biol.", "date": "2006", "authors": "Arasada Rajesh, Son Hyunju, Ramalingam Nagendran, Eichinger Ludwig, Schleicher Michael, Rohlfs Meino", "reference": { "type": "PubMed", "id": "16842885", "url": "https://pubmed.ncbi.nlm.nih.gov/16842885" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54EY4-1", "protein_name": "Serine/threonine-protein kinase dst3", "gene_name": "dst3", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54JG7-1", "protein_name": "Serine/threonine-protein kinase dst4", "gene_name": "dst4", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54XL6-1", "protein_name": "Serine/threonine-protein kinase fray1", "gene_name": "fray1", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H4-1", "protein_name": "Serine/threonine-protein kinase fray2", "gene_name": "fray2", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IX1-1", "protein_name": "Serine/threonine-protein kinase dst1", "gene_name": "dst1", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "O61125-1", "protein_name": "Serine/threonine-protein kinase 4 homolog A", "gene_name": "krsA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GC2-1", "protein_name": "Serine/threonine-protein kinase dst2", "gene_name": "dst2", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54EY4", "url": "https://www.uniprot.org/uniprotkb/Q54EY4" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.16842885", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "NADPH oxidase homologs are required for normal cell differentiation and morphogenesis in Dictyostelium discoideum.", "journal": "Biochim. Biophys. Acta", "date": "2005", "authors": "Lardy Bernard, Bof Mireille, Aubry Laurence, Paclet Marie H\u00e9l\u00e8ne, Morel Fran\u00e7oise, Satre Michel, Klein G\u00e9rard", "reference": { "type": "PubMed", "id": "15950752", "url": "https://pubmed.ncbi.nlm.nih.gov/15950752" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54F44-1", "protein_name": "Superoxide-generating NADPH oxidase heavy chain subunit C", "gene_name": "noxC", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86GL4-1", "protein_name": "Superoxide-generating NADPH oxidase heavy chain subunit B", "gene_name": "noxB", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9XYS3-1", "protein_name": "Superoxide-generating NADPH oxidase heavy chain subunit A", "gene_name": "noxA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q867T7-1", "protein_name": "NADPH oxidase activator", "gene_name": "ncfA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q867X6-1", "protein_name": "Superoxide-generating NADPH oxidase light chain subunit", "gene_name": "cybA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54F44", "url": "https://www.uniprot.org/uniprotkb/Q54F44" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.15950752", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 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"field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The homeobox-containing gene Wariai regulates anterior-posterior patterning and cell-type homeostasis in Dictyostelium.", "journal": "Development (Cambridge, England)", "date": "1998-01", "authors": "Han Z, Firtel R A", "reference": { "type": "PubMed", "id": "9486804", "url": "https://pubmed.ncbi.nlm.nih.gov/9486804" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54F46-1", "protein_name": "Homeobox protein Wariai", "gene_name": "warA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869W0-1", "protein_name": "Homeobox protein 2", "gene_name": "hbx2", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54F46", "url": "https://www.uniprot.org/uniprotkb/Q54F46" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.9486804", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.", "journal": "Nature chemical biology", "date": "2006-09", "authors": "Austin Michael B, Saito Tamao, Bowman Marianne E, Haydock Stephen, Kato Atsushi, Moore Bradley S, Kay Robert R, Noel Joseph P", "reference": { "type": "PubMed", "id": "16906151", "url": "https://pubmed.ncbi.nlm.nih.gov/16906151" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54FI3-1", "protein_name": "Polyketide synthase 37", "gene_name": "StlB", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E72-1", "protein_name": "Probable polyketide synthase 1", "gene_name": "stlA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8T638-1", "protein_name": "Des-methyl DIF-1 methyltransferase A", "gene_name": "dmtA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54FI3", "url": "https://www.uniprot.org/uniprotkb/Q54FI3" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.16906151", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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flavin-dependent halogenase catalyzes the chlorination step in the biosynthesis of Dictyostelium differentiation-inducing factor 1.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2010-03-30", "authors": "Neumann Christopher S, Walsh Christopher T, Kay Robert R", "reference": { "type": "PubMed", "id": "20231486", "url": "https://pubmed.ncbi.nlm.nih.gov/20231486" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54FI3-1", "protein_name": "Polyketide synthase 37", "gene_name": "StlB", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8T638-1", "protein_name": "Des-methyl DIF-1 methyltransferase A", "gene_name": "dmtA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54FI3", "url": "https://www.uniprot.org/uniprotkb/Q54FI3" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Characterization of recombinant Dictyostelium discoideum sepiapterin reductase expressed in E. coli.", "journal": "Molecules and cells", "date": "2000-08-31", "authors": "Kim Y A, Chung H J, Kim Y J, Choi Y K, Hwang Y K, Lee S W, Park Y S", "reference": { "type": "PubMed", "id": "10987137", "url": "https://pubmed.ncbi.nlm.nih.gov/10987137" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54GP3-1", "protein_name": "Sepiapterin reductase", "gene_name": "sprA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54GP3", "url": "https://www.uniprot.org/uniprotkb/Q54GP3" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.10987137", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "D-threo-tetrahydrobiopterin is synthesized via 1'-oxo-2'-D-hydroxypropyl-tetrahydropterin in Dictyostelium discoideum Ax2.", "journal": "FEBS letters", "date": "2005-06-06", "authors": "Choi Yong Kee, Park Jung Soon, Kong Jin Seon, Morio Takahiro, Park Young Shik", "reference": { "type": "PubMed", "id": "15896778", "url": "https://pubmed.ncbi.nlm.nih.gov/15896778" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54GP3-1", "protein_name": "Sepiapterin reductase", "gene_name": "sprA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54GP3", "url": "https://www.uniprot.org/uniprotkb/Q54GP3" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.15896778", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional role of sepiapterin reductase in the biosynthesis of tetrahydropteridines in Dictyostelium discoideum Ax2.", "journal": "Biochimica et biophysica acta", "date": "2006-06", "authors": "Choi Yong Kee, Kong Jin Sun, Park Young Shik", "reference": { "type": "PubMed", "id": "16527408", "url": "https://pubmed.ncbi.nlm.nih.gov/16527408" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54GP3-1", "protein_name": "Sepiapterin reductase", "gene_name": "sprA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54GP3", "url": "https://www.uniprot.org/uniprotkb/Q54GP3" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.16527408", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tetrahydropteridine deficiency impairs mitochondrial function in Dictyostelium discoideum Ax2.", "journal": "FEBS letters", "date": "2007-11-27", "authors": "Kim Hye-Lim, Choi Yong Kee, Kim Do Hyung, Park Sun Ok, Han Jin, Park Young Shik", "reference": { "type": "PubMed", "id": "17976377", "url": "https://pubmed.ncbi.nlm.nih.gov/17976377" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54GP3-1", "protein_name": "Sepiapterin reductase", "gene_name": "sprA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54GP3", "url": "https://www.uniprot.org/uniprotkb/Q54GP3" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.17976377", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Reduced glutathione levels affect the culmination and cell fate decision in Dictyostelium discoideum.", "journal": "Developmental biology", "date": "2006-07-15", "authors": "Choi Chang-Hoon, Kim Beom-Jun, Jeong Sun-Young, Lee Chang-Hun, Kim Ji-Sun, Park Seong-Jun, Yim Hyung-Soon, Kang Sa-Ouk", "reference": { "type": "PubMed", "id": "16678813", "url": "https://pubmed.ncbi.nlm.nih.gov/16678813" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54GP8-1", "protein_name": "Glutaredoxin", "gene_name": "grxA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8T137-1", "protein_name": "Glutathione reductase", "gene_name": "gsr", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54GP8", "url": "https://www.uniprot.org/uniprotkb/Q54GP8" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.16678813", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The novel ankyrin-repeat containing kinase ARCK-1 acts as a suppressor of the Spalten signaling pathway during Dictyostelium development.", "journal": "Developmental biology", "date": "2003-11-15", "authors": "Aubry Laurence, Lee Susan, Ravanel Kissia, Firtel Richard A", "reference": { "type": "PubMed", "id": "14597204", "url": "https://pubmed.ncbi.nlm.nih.gov/14597204" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54HC6-1", "protein_name": "Ankyrin repeat-containing protein kinase A", "gene_name": "arkA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "O15743-1", "protein_name": "Protein spalten", "gene_name": "spnA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54HC6", "url": "https://www.uniprot.org/uniprotkb/Q54HC6" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" 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Kammerer R A, Steinmetz M O, Bourenkov G P, Aebi U", "reference": { "type": "PubMed", "id": "10745004", "url": "https://pubmed.ncbi.nlm.nih.gov/10745004" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54HG2-1", "protein_name": "Cortexillin-1", "gene_name": "ctxA", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54HG2", "url": "https://www.uniprot.org/uniprotkb/Q54HG2" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.10745004", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of Rap1 activity by RapGAP1 controls cell adhesion at the front of chemotaxing cells.", "journal": "The Journal of cell biology", "date": "2007-12-03", "authors": "Jeon Taeck J, Lee Dai-Jen, Lee Susan, Weeks Gerald, Firtel Richard A", "reference": { "type": "PubMed", "id": "18039932", "url": "https://pubmed.ncbi.nlm.nih.gov/18039932" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54HG2-1", "protein_name": "Cortexillin-1", "gene_name": "ctxA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q75J96-1", "protein_name": "RapA guanosine triphosphatase-activating protein 1", "gene_name": "rapgap1", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54HG2", "url": "https://www.uniprot.org/uniprotkb/Q54HG2" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.18039932", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cortexillins, major determinants of cell shape and size, are actin-bundling proteins with a parallel coiled-coil tail.", "journal": "Cell", "date": "1996", "authors": "Faix J, Steinmetz M, Boves H, Kammerer R A, Lottspeich F, Mintert U, Murphy J, Stock A, Aebi U, Gerisch G", "reference": { "type": "PubMed", "id": "8752217", "url": "https://pubmed.ncbi.nlm.nih.gov/8752217" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54HG2-1", "protein_name": "Cortexillin-1", "gene_name": "ctxA", "tax_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q550R2-1", "protein_name": "Cortexillin-2", "gene_name": "ctxB", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54HG2", "url": "https://www.uniprot.org/uniprotkb/Q54HG2" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.8752217", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Metal ion dependency of serine racemase from Dictyostelium discoideum.", "journal": "Amino acids", "date": "2012-10", "authors": "Ito Tomokazu, Murase Hirotaka, Maekawa Motoki, Goto Masaru, Hayashi Shuhei, Saito Hajime, Maki Masatoshi, Hemmi Hisashi, Yoshimura Tohru", "reference": { "type": "PubMed", "id": "22311068", "url": "https://pubmed.ncbi.nlm.nih.gov/22311068" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54HH2-1", "protein_name": "Serine racemase", "gene_name": "srr", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54HH2", "url": "https://www.uniprot.org/uniprotkb/Q54HH2" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "mutagenesis": [ { "start_pos": 207, "end_pos": 207, "sequence_org": "E", "sequence_mut": "A", "comment": "Retains 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Proteins and proteomics", "date": "2020-09", "authors": "Ito Tomokazu, Matsuoka Mai, Goto Masaru, Watanabe Soichiro, Mizobuchi Taichi, Matsushita Kazuma, Nasu Ryoma, Hemmi Hisashi, Yoshimura Tohru", "reference": { "type": "PubMed", "id": "32474107", "url": "https://pubmed.ncbi.nlm.nih.gov/32474107" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q54HH2-1", "protein_name": "Serine racemase", "gene_name": "srr", "tax_name": "Social amoeba" } ], "species": [ { "name": "Dictyostelium discoideum", "taxid": 44689, "evidence": [ { "database": "UniProtKB", "id": "Q54HH2", "url": "https://www.uniprot.org/uniprotkb/Q54HH2" } ], "common_name": "Social amoeba", "glygen_name": "Cellular slime mold", "reference_species": "Dictyostelium discoideum [44689]" } ], "record_id": "pubmed.32474107", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification and cell cycle-dependent localization of nine novel, genuine centrosomal components in Dictyostelium discoideum.", "journal": "Cell Motil. 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