[ { "title": "Trafficking to the ciliary membrane: how to get across the periciliary diffusion barrier?", "journal": "Annual review of cell and developmental biology", "date": "2010", "authors": "Nachury MV, Seeley ES, Jin H", "reference": { "type": "PubMed", "id": "19575670", "url": "https://pubmed.ncbi.nlm.nih.gov/19575670" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P49368-1", "protein_name": "T-complex protein 1 subunit gamma", "gene_name": "CCT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50991-1", "protein_name": "T-complex protein 1 subunit delta", "gene_name": "CCT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32745-1", "protein_name": "Somatostatin receptor type 3", "gene_name": "SSTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99835-1", "protein_name": "Protein smoothened", "gene_name": "SMO", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3SYG4-1", "protein_name": "Protein PTHB1", "gene_name": "BBS9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3I7-1", "protein_name": "BBSome complex member BBS5", "gene_name": "BBS5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F7-1", "protein_name": "ADP-ribosylation factor-like protein 6", "gene_name": "ARL6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TAM2-1", "protein_name": "Tetratricopeptide repeat protein 8", "gene_name": "TTC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17987-1", "protein_name": "T-complex protein 1 subunit alpha", "gene_name": "TCP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96QF0-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "RAB3IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFJ9-1", "protein_name": "BBSome complex member BBS1", "gene_name": "BBS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWZ6-1", "protein_name": "BBSome complex member BBS7", "gene_name": "BBS7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RK4-1", "protein_name": "BBSome complex member BBS4", "gene_name": "BBS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXC9-1", "protein_name": "BBSome complex member BBS2", "gene_name": "BBS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TAM1-1", "protein_name": "BBSome complex assembly protein BBS10", "gene_name": "BBS10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZW61-1", "protein_name": "Chaperonin-containing T-complex member BBS12", "gene_name": "BBS12", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MTZ0-1", "protein_name": "BBSome-interacting protein 1", "gene_name": "BBIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78371-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "CCT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPJ1-1", "protein_name": "Molecular chaperone MKKS", "gene_name": "MKKS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48643-1", "protein_name": "T-complex protein 1 subunit epsilon", "gene_name": "CCT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQ48-1", "protein_name": "Leucine zipper transcription factor-like protein 1", "gene_name": "LZTFL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99705-1", "protein_name": "Melanin-concentrating hormone receptor 1", "gene_name": "MCHR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50990-1", "protein_name": "T-complex protein 1 subunit theta", "gene_name": "CCT8", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P49368", "url": "https://www.uniprot.org/uniprotkb/P49368" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19575670", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], 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"gene_name": "TTC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17987-1", "protein_name": "T-complex protein 1 subunit alpha", "gene_name": "TCP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96QF0-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "RAB3IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFJ9-1", "protein_name": "BBSome complex member BBS1", "gene_name": "BBS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IWZ6-1", "protein_name": "BBSome complex member BBS7", "gene_name": "BBS7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RK4-1", "protein_name": "BBSome complex member BBS4", "gene_name": "BBS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXC9-1", "protein_name": "BBSome complex member BBS2", "gene_name": "BBS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TAM1-1", "protein_name": "BBSome complex assembly protein BBS10", "gene_name": "BBS10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZW61-1", "protein_name": "Chaperonin-containing T-complex member BBS12", "gene_name": "BBS12", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8MTZ0-1", "protein_name": "BBSome-interacting protein 1", "gene_name": "BBIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78371-1", "protein_name": "T-complex protein 1 subunit beta", "gene_name": "CCT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPJ1-1", "protein_name": "Molecular chaperone MKKS", "gene_name": "MKKS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48643-1", "protein_name": "T-complex protein 1 subunit epsilon", "gene_name": "CCT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQ48-1", "protein_name": "Leucine zipper transcription factor-like protein 1", "gene_name": "LZTFL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99705-1", "protein_name": "Melanin-concentrating hormone receptor 1", "gene_name": "MCHR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50990-1", "protein_name": "T-complex protein 1 subunit theta", "gene_name": "CCT8", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P49368", "url": "https://www.uniprot.org/uniprotkb/P49368" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 81, "end_pos": 81, "sequence_org": "D", "sequence_mut": "N", "comment": "Greatly decreases all interactions with BBS7, BBS9 and BBS12 indicating that this residue may be required for overall protein conformation rather than required for ATP binding and substrate folding.", "evidence": [ { "database": "UniProtKB", "id": "Q8TAM1", "url": "https://www.uniprot.org/uniprotkb/Q8TAM1" }, { "database": "PubMed", "id": "20080638", "url": "https://pubmed.ncbi.nlm.nih.gov/20080638" } ], "uniprot_canonical_ac": "Q8TAM1-1" } ], "record_id": "pubmed.20080638", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], 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"common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 24, "end_pos": 25, "sequence_org": "KR", "sequence_mut": "AS", "comment": "Increases BBS4, BBS8 and BBS9 ciliary localization.", "evidence": [ { "database": "UniProtKB", "id": "Q9NQ48", "url": "https://www.uniprot.org/uniprotkb/Q9NQ48" }, { "database": "PubMed", "id": "22072986", "url": "https://pubmed.ncbi.nlm.nih.gov/22072986" } ], "uniprot_canonical_ac": "Q9NQ48-1" } ], "record_id": "pubmed.22072986", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 31 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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and chaperonin-assisted sequential assembly of stable bardet-biedl syndrome protein complex, the BBSome.", "journal": "The Journal of biological chemistry", "date": "2012", "authors": "Zhang Q, Yu D, Seo S, Stone EM, Sheffield VC", "reference": { "type": "PubMed", "id": "22500027", "url": "https://pubmed.ncbi.nlm.nih.gov/22500027" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P49368-1", "protein_name": "T-complex protein 1 subunit gamma", "gene_name": "CCT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50991-1", "protein_name": "T-complex protein 1 subunit delta", "gene_name": "CCT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32745-1", "protein_name": "Somatostatin receptor type 3", "gene_name": "SSTR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99835-1", "protein_name": "Protein smoothened", "gene_name": "SMO", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3SYG4-1", "protein_name": "Protein PTHB1", "gene_name": "BBS9", 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Signaling Pathway in Gender-Disparity Hepatocarcinogenesis.", "journal": "Cells", "date": "2021", "authors": "Tsai YW, Jeng KS, He MK, Hsieh YW, Lai HH, Lai CY, Huang CC, Chang CF, Huang CT, Her GM", "reference": { "type": "PubMed", "id": "34943942", "url": "https://pubmed.ncbi.nlm.nih.gov/34943942" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BW11-1", "protein_name": "Max dimerization protein 3", "gene_name": "MXD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6YLH9-1", "protein_name": "Caveolin", "gene_name": "cav1", "tax_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5XIY8-1", "protein_name": "PAX-interacting protein 1", "gene_name": "paxip1", "tax_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7SX95-1", "protein_name": "Max dimerization protein 3", "gene_name": "mxd3", "tax_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1NTE7-1", "protein_name": "Collagen, type V, alpha 2a precursor", "gene_name": "col5a2a", "tax_name": 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional organization of the human uncoupling protein-2 gene, and juxtaposition to the uncoupling protein-3 gene.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1999", "authors": "Pecqueur C, Cassard-Doulcier A M, Raimbault S, Miroux B, Fleury C, Gelly C, Bouillaud F, Ricquier D", "reference": { "type": "PubMed", "id": "10082652", "url": "https://pubmed.ncbi.nlm.nih.gov/10082652" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55851-1", "protein_name": "Dicarboxylate carrier SLC25A8", "gene_name": "UCP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55851", "url": "https://www.uniprot.org/uniprotkb/P55851" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10082652", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", 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is associated with decreased risk of obesity in middle-aged humans.", "journal": "Nat. Genet.", "date": "2001", "authors": "Esterbauer H, Schneitler C, Oberkofler H, Ebenbichler C, Paulweber B, Sandhofer F, Ladurner G, Hell E, Strosberg A D, Patsch J R, Krempler F, Patsch W", "reference": { "type": "PubMed", "id": "11381268", "url": "https://pubmed.ncbi.nlm.nih.gov/11381268" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55851-1", "protein_name": "Dicarboxylate carrier SLC25A8", "gene_name": "UCP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55851", "url": "https://www.uniprot.org/uniprotkb/P55851" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11381268", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia.", "journal": "Nat. Genet.", "date": "1997", "authors": "Fleury C, Neverova M, Collins S, Raimbault S, Champigny O, Levi-Meyrueis C, Bouillaud F, Seldin M F, Surwit R S, Ricquier D, Warden C H", "reference": { "type": "PubMed", "id": "9054939", "url": "https://pubmed.ncbi.nlm.nih.gov/9054939" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55851-1", "protein_name": "Dicarboxylate carrier SLC25A8", "gene_name": "UCP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55851", "url": "https://www.uniprot.org/uniprotkb/P55851" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9054939", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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"Structure and organization of the human uncoupling protein 2 gene and identification of a common biallelic variant in Caucasian and African-American subjects.", "journal": "Diabetes", "date": "1998", "authors": "Argyropoulos G, Brown A M, Peterson R, Likes C E, Watson D K, Garvey W T", "reference": { "type": "PubMed", "id": "9568704", "url": "https://pubmed.ncbi.nlm.nih.gov/9568704" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55851-1", "protein_name": "Dicarboxylate carrier SLC25A8", "gene_name": "UCP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55851", "url": "https://www.uniprot.org/uniprotkb/P55851" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9568704", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { 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"authors": "Zhang Z, Wu Q, He Y, Lu P, Li D, Yang M, Gu W, Liu R, Hong J, Wang J", "reference": { "type": "PubMed", "id": "33776928", "url": "https://pubmed.ncbi.nlm.nih.gov/33776928" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P78415-1", "protein_name": "Iroquois-class homeodomain protein IRX-3", "gene_name": "IRX3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P78415", "url": "https://www.uniprot.org/uniprotkb/P78415" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33776928", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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population: a possible risk increases of body weight excess.", "journal": "Colombia medica (Cali, Colombia)", "date": "2022", "authors": "Ruiz-D\u00edaz Mar\u00eda Stephany, Mena-Yi Diana, G\u00f3mez-Camargo Doris, Mora-Garc\u00eda Gustavo", "reference": { "type": "PubMed", "id": "36415696", "url": "https://pubmed.ncbi.nlm.nih.gov/36415696" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P78415-1", "protein_name": "Iroquois-class homeodomain protein IRX-3", "gene_name": "IRX3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P78415", "url": "https://www.uniprot.org/uniprotkb/P78415" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36415696", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", 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"reference": { "type": "PubMed", "id": "10753868", "url": "https://pubmed.ncbi.nlm.nih.gov/10753868" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q15077-1", "protein_name": "P2Y purinoceptor 6", "gene_name": "P2RY6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P47900-1", "protein_name": "P2Y purinoceptor 1", "gene_name": "P2RY1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00398-1", "protein_name": "Putative P2Y purinoceptor 10", "gene_name": "P2RY10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H244-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2RY12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41231-1", "protein_name": "P2Y purinoceptor 2", "gene_name": "P2RY2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96G91-1", "protein_name": "P2Y purinoceptor 11", "gene_name": "P2RY11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BPV8-1", "protein_name": "P2Y purinoceptor 13", "gene_name": "P2RY13", 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