[ { "title": "SIRT1 promotes the progression and chemoresistance of colorectal cancer through the p53/miR-101/KPNA3 axis.", "journal": "Cancer biology & therapy", "date": "2023-12-31", "authors": "Wang Xiao-Wei, Jiang Ying-Hao, Ye Wei, Shao Chun-Fa, Xie Jian-Jin, Li Xia", "reference": { "type": "PubMed", "id": "37575080", "url": "https://pubmed.ncbi.nlm.nih.gov/37575080" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00505-1", "protein_name": "Importin subunit alpha-4", "gene_name": "KPNA3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00505", "url": "https://www.uniprot.org/uniprotkb/O00505" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.37575080", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Isolation and mapping of karyopherin alpha 3 (KPNA3), a human gene that is highly homologous to genes encoding Xenopus importin, yeast SRP1 and human RCH1.", "journal": "Cytogenet. Cell Genet.", "date": "1997", "authors": "Takeda S, Fujiwara T, Shimizu F, Kawai A, Shinomiya K, Okuno S, Ozaki K, Katagiri T, Shimada Y, Nagata M, Watanabe T, Takaichi A, Kuga Y, Suzuki M, Hishigaki H, Takahashi E, Shin S, Nakamura Y, Hirai Y", "reference": { "type": "PubMed", "id": "9154134", "url": "https://pubmed.ncbi.nlm.nih.gov/9154134" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00505-1", "protein_name": "Importin subunit alpha-4", "gene_name": "KPNA3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00505", "url": "https://www.uniprot.org/uniprotkb/O00505" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9154134", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning and characterization of hSRP1 gamma, a tissue-specific nuclear transport factor.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1998", "authors": "Nachury M V, Ryder U W, Lamond A I, Weis K", "reference": { "type": "PubMed", "id": "9435235", "url": "https://pubmed.ncbi.nlm.nih.gov/9435235" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00505-1", "protein_name": "Importin subunit alpha-4", "gene_name": "KPNA3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00505", "url": "https://www.uniprot.org/uniprotkb/O00505" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9435235", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).", "journal": "Biochimica et biophysica acta", "date": "2000", "authors": "Caricasole A, Sala C, Roncarati R, Formenti E, Terstappen GC", "reference": { "type": "PubMed", "id": "11118617", "url": "https://pubmed.ncbi.nlm.nih.gov/11118617" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50148-1", "protein_name": "Guanine nucleotide-binding protein G(q) subunit alpha", "gene_name": "GNAQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51178-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1", "gene_name": "PLCD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92835-1", "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1", "gene_name": "INPP5D", "tax_name": "Human" }, { 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"Q15735-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase A", "gene_name": "INPP5J", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DP23-1", "protein_name": "Calmodulin-1", "gene_name": "CALM1; CALM2; CALM3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQ66-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1", "gene_name": "PLCB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75038-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2", "gene_name": "PLCH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4KWH8-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1", "gene_name": "PLCH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95837-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha-14", "gene_name": "GNA14", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15357-1", "protein_name": "Phosphatidylinositol 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beta-4", "gene_name": "PLCB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3E9-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3", "gene_name": "PLCD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01970-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3", "gene_name": "PLCB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BZ4-1", "protein_name": "5'-3' exonuclease PLD4", "gene_name": "PLD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43426-1", "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1", "gene_name": "SYNJ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29992-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha-11", "gene_name": "GNA11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30679-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha-15", "gene_name": "GNA15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DU7-1", "protein_name": "Inositol-trisphosphate 3-kinase C", "gene_name": "ITPKC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13572-1", "protein_name": "Inositol-tetrakisphosphate 1-kinase", "gene_name": "ITPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14573-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "ITPR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32019-1", "protein_name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "gene_name": "INPP5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The versatility and universality of calcium signalling.", "journal": "Nature reviews. Molecular cell biology", "date": "2000", "authors": "Berridge MJ, Lipp P, Bootman MD", "reference": { "type": "PubMed", "id": "11413485", "url": "https://pubmed.ncbi.nlm.nih.gov/11413485" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49619-1", "protein_name": "Diacylglycerol kinase gamma", "gene_name": "DGKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6T7-1", "protein_name": "Diacylglycerol kinase beta", "gene_name": "DGKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23743-1", "protein_name": "Diacylglycerol kinase alpha", "gene_name": "DGKA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13574-2", "protein_name": "Diacylglycerol kinase zeta", "gene_name": "DGKZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7LDG7-1", "protein_name": "RAS guanyl-releasing protein 2", "gene_name": "RASGRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24723-1", "protein_name": "Protein kinase C eta type", "gene_name": "PRKCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14571-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "ITPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05655-1", "protein_name": "Protein kinase C delta type", "gene_name": "PRKCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13507-2", "protein_name": "Short transient receptor potential channel 3", "gene_name": "TRPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02156-1", "protein_name": "Protein kinase C epsilon type", "gene_name": "PRKCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04759-1", "protein_name": "Protein kinase C theta type", "gene_name": "PRKCQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52824-1", "protein_name": "Diacylglycerol kinase theta", "gene_name": "DGKQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5KSL6-1", "protein_name": "Diacylglycerol kinase kappa", "gene_name": "DGKK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95267-1", "protein_name": "RAS guanyl-releasing protein 1", "gene_name": "RASGRP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCX4-1", "protein_name": "Short transient receptor potential channel 7", "gene_name": "TRPC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75912-2", "protein_name": "Diacylglycerol kinase iota", "gene_name": "DGKI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16760-1", "protein_name": "Diacylglycerol kinase delta", "gene_name": "DGKD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XP1-1", "protein_name": "Diacylglycerol kinase eta", "gene_name": "DGKH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52429-1", "protein_name": "Diacylglycerol kinase epsilon", "gene_name": "DGKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14573-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "ITPR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y210-1", "protein_name": "Short transient receptor potential channel 6", "gene_name": "TRPC6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11413485", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning and functional expression of human short TRP7, a candidate protein for store-operated Ca2+ influx.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Riccio A, Mattei C, Kelsell RE, Medhurst AD, Calver AR, Randall AD, Davis JB, Benham CD, Pangalos MN", "reference": { "type": "PubMed", "id": "11805119", "url": "https://pubmed.ncbi.nlm.nih.gov/11805119" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15547-1", "protein_name": "P2X purinoceptor 6", "gene_name": "P2RX6", "tax_name": 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"gene_name": "PRKCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14571-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "ITPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05655-1", "protein_name": "Protein kinase C delta type", "gene_name": "PRKCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93086-6", "protein_name": "P2X purinoceptor 5", "gene_name": "P2RX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56373-1", "protein_name": "P2X purinoceptor 3", "gene_name": "P2RX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51575-1", "protein_name": "P2X purinoceptor 1", "gene_name": "P2RX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL9-1", "protein_name": "P2X purinoceptor 2", "gene_name": "P2RX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D31-1", "protein_name": "Calcium release-activated calcium channel protein 1", "gene_name": "ORAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99571-1", "protein_name": "P2X purinoceptor 4", "gene_name": "P2RX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13507-2", "protein_name": "Short transient receptor potential channel 3", "gene_name": "TRPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02156-1", "protein_name": "Protein kinase C epsilon type", "gene_name": "PRKCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99572-1", "protein_name": "P2X purinoceptor 7", "gene_name": "P2RX7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04759-1", "protein_name": "Protein kinase C theta type", "gene_name": "PRKCQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52824-1", "protein_name": "Diacylglycerol kinase theta", "gene_name": "DGKQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5KSL6-1", "protein_name": "Diacylglycerol kinase kappa", "gene_name": "DGKK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95267-1", "protein_name": "RAS guanyl-releasing protein 1", "gene_name": "RASGRP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCX4-1", "protein_name": "Short transient receptor potential channel 7", "gene_name": "TRPC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75912-2", "protein_name": "Diacylglycerol kinase iota", "gene_name": "DGKI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16760-1", "protein_name": "Diacylglycerol kinase delta", "gene_name": "DGKD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XP1-1", "protein_name": "Diacylglycerol kinase eta", "gene_name": "DGKH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52429-1", "protein_name": "Diacylglycerol kinase epsilon", "gene_name": "DGKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14573-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "ITPR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y210-1", "protein_name": "Short transient receptor potential channel 6", "gene_name": "TRPC6", "tax_name": "Human" } ], 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of a family of calcium sensors as protein ligands of inositol trisphosphate receptor Ca(2+) release channels.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Yang J, McBride S, Mak DO, Vardi N, Palczewski K, Haeseleer F, Foskett JK", "reference": { "type": "PubMed", "id": "12032348", "url": "https://pubmed.ncbi.nlm.nih.gov/12032348" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O88751-1", "protein_name": "Calcium-binding protein 1", "gene_name": "Cabp1", "tax_name": "Rat" }, { "uniprot_canonical_ac": "P29994-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "Itpr1", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q14571-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "ITPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q63269-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "Itpr3", "tax_name": "Rat" }, { "uniprot_canonical_ac": "P29995-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "Itpr2", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q9NZU7-4", "protein_name": "Calcium-binding protein 1", "gene_name": "CABP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14573-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "ITPR3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 238, "end_pos": 238, "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of magnesium-binding. 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"title": "Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins.", "journal": "EMBO J.", "date": "2004", "authors": "Kasri NN, Holmes AM, Bultynck G, Parys JB, Bootman MD, Rietdorf K, Missiaen L, McDonald F, De Smedt H, Conway SJ, Holmes AB, Berridge MJ, Roderick HL", "reference": { "type": "PubMed", "id": "14685260", "url": "https://pubmed.ncbi.nlm.nih.gov/14685260" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZU7-4", "protein_name": "Calcium-binding protein 1", "gene_name": "CABP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The contribution of serine residues 1588 and 1755 to phosphorylation of the type I inositol 1,4,5-trisphosphate receptor by PKA and PKG.", "journal": "FEBS letters", "date": "2004", "authors": "Soulsby MD, Alzayady K, Xu Q, Wojcikiewicz RJ", "reference": { "type": "PubMed", "id": "14741364", "url": "https://pubmed.ncbi.nlm.nih.gov/14741364" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1598, "end_pos": 1598, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "23186163", "url": "https://pubmed.ncbi.nlm.nih.gov/23186163" }, { "database": "PubMed", "id": "17081983", "url": "https://pubmed.ncbi.nlm.nih.gov/17081983" }, { "database": "PubMed", "id": "18669648", "url": "https://pubmed.ncbi.nlm.nih.gov/18669648" }, { "database": "PubMed", "id": "24275569", "url": "https://pubmed.ncbi.nlm.nih.gov/24275569" }, { "database": "iPTMnet", "id": "Q14643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14643" }, { "database": "PubMed", "id": "14741364", "url": "https://pubmed.ncbi.nlm.nih.gov/14741364" }, { "database": "PubMed", "id": "17696464", "url": "https://pubmed.ncbi.nlm.nih.gov/17696464" } ], "site_lbl": "Ser1598", "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 1764, "end_pos": 1764, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKA", "evidence": [ { "database": "UniProtKB", "id": 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"Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 353, "end_pos": 353, "kinase_uniprot_canonical_ac": "P06241-1", "kinase_gene_name": "FYN", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14643" }, { "database": "PubMed", "id": "14761954", "url": "https://pubmed.ncbi.nlm.nih.gov/14761954" } ], "site_lbl": "Tyr353", "uniprot_canonical_ac": "Q14643-1" } ], "record_id": "pubmed.14761954", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Subtype-specific and ER lumenal environment-dependent regulation of inositol 1,4,5-trisphosphate receptor type 1 by ERp44.", "journal": "Cell", "date": "2005", "authors": "Higo T, Hattori M, Nakamura T, Natsume T, Michikawa T, Mikoshiba K", "reference": { "type": "PubMed", "id": "15652484", "url": "https://pubmed.ncbi.nlm.nih.gov/15652484" }, "referenced_glycans": [], 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Significant decrease of interaction with ERP44. Complete loss of channel inhibition by ERP44.", "evidence": [ { "database": "UniProtKB", "id": "P11881", "url": "https://www.uniprot.org/uniprotkb/P11881" }, { "database": "PubMed", "id": "15652484", "url": "https://pubmed.ncbi.nlm.nih.gov/15652484" } ], "uniprot_canonical_ac": "P11881-1" }, { "start_pos": 2504, "end_pos": 2504, "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on channel activity. Significant decrease of interaction with ERP44. Complete loss of channel inhibition by ERP44.", "evidence": [ { "database": "UniProtKB", "id": "P11881", "url": "https://www.uniprot.org/uniprotkb/P11881" }, { "database": "PubMed", "id": "15652484", "url": "https://pubmed.ncbi.nlm.nih.gov/15652484" } ], "uniprot_canonical_ac": "P11881-1" }, { "start_pos": 2527, "end_pos": 2527, "sequence_org": "C", "sequence_mut": "S", "comment": "Complete loss of channel activity. Significant decrease of interaction with ERP44.", "evidence": [ { "database": "UniProtKB", "id": "P11881", "url": "https://www.uniprot.org/uniprotkb/P11881" }, { "database": "PubMed", "id": "15652484", "url": "https://pubmed.ncbi.nlm.nih.gov/15652484" } ], "uniprot_canonical_ac": "P11881-1" } ], "record_id": "pubmed.15652484", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cdc2/cyclin B1 interacts with and modulates inositol 1,4,5-trisphosphate receptor (type 1) functions.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2005", "authors": "Malathi K, Li X, Krizanova O, Ondrias K, Sperber K, Ablamunits V, Jayaraman T", "reference": { "type": "PubMed", "id": "16237118", "url": "https://pubmed.ncbi.nlm.nih.gov/16237118" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 421, "end_pos": 421, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14643" }, { "database": "PubMed", "id": "14635192", "url": "https://pubmed.ncbi.nlm.nih.gov/14635192" }, { "database": "PubMed", "id": "16237118", "url": "https://pubmed.ncbi.nlm.nih.gov/16237118" } ], "site_lbl": "Ser421", "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 800, "end_pos": 800, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14643" }, { "database": "PubMed", "id": "14635192", "url": "https://pubmed.ncbi.nlm.nih.gov/14635192" }, { "database": "PubMed", "id": "16237118", "url": "https://pubmed.ncbi.nlm.nih.gov/16237118" } ], "site_lbl": "Thr800", "uniprot_canonical_ac": "Q14643-1" } ], "record_id": "pubmed.16237118", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Khan MT, Wagner L 2nd, Yule DI, Bhanumathy C, Joseph SK", "reference": { "type": "PubMed", "id": "16332683", "url": "https://pubmed.ncbi.nlm.nih.gov/16332683" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 2690, "end_pos": 2690, "kinase_uniprot_canonical_ac": "P31749-1", "kinase_gene_name": "AKT1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14643" }, { "database": "PubMed", "id": "16332683", "url": "https://pubmed.ncbi.nlm.nih.gov/16332683" } ], "site_lbl": "Ser2690", "uniprot_canonical_ac": "Q14643-1" } ], "record_id": "pubmed.16332683", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IRBIT suppresses IP3 receptor activity by competing with IP3 for the common binding site on the IP3 receptor.", "journal": "Molecular cell", "date": "2006", "authors": "Ando H, Mizutani A, Kiefer H, Tsuzurugi D, Michikawa T, Mikoshiba K", "reference": { "type": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43865-1", "protein_name": "S-adenosylhomocysteine hydrolase-like protein 1", "gene_name": "AHCYL1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 241, "end_pos": 241, "sequence_org": "R", "sequence_mut": "Q", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 249, "end_pos": 249, "sequence_org": "K", "sequence_mut": "Q", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 265, "end_pos": 265, "sequence_org": "R", "sequence_mut": "Q", "comment": "No effect on interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 267, "end_pos": 267, "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 269, "end_pos": 269, "sequence_org": "R", "sequence_mut": "Q", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 504, "end_pos": 504, "sequence_org": "R", "sequence_mut": "Q", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 506, "end_pos": 506, "sequence_org": "R", "sequence_mut": "Q", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 508, "end_pos": 508, "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 511, "end_pos": 511, "sequence_org": "R", "sequence_mut": "A", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 567, "end_pos": 567, "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 568, "end_pos": 568, "sequence_org": "R", "sequence_mut": "Q", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 569, "end_pos": 569, "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes interaction with AHCYL1.", "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" } ], "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on interaction with ITPR1. No effect on phosphorylation. No effect on interaction with SLC4A4. No effect on interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 66, "end_pos": 66, "sequence_org": "S", "sequence_mut": "A", "comment": "Slightly decreases interaction with ITPR1. Slightly decreases phosphorylation. No effect on interaction with SLC4A4. Abolishes interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 68, "end_pos": 68, "sequence_org": "S", "sequence_mut": "A", "comment": "Highly decreases phosphorylation. Abolishes interaction with ITPR1. No effect on interaction with BCL2L10. Marked decrease in interaction of BCL2L10 with ITPR1. Decreased ability of BCL2L10 to reduce ITPR1-mediated calcium release and to prevent apoptosis. No effect on formation of multimers. Abolishes interaction with SLC4A4. Abolishes interaction with FIP1L1. Highly decreases interaction with SLC9A3. Highly decreases interaction with SLC9A3; when associated with A-71 and A-74.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "20584908", "url": "https://pubmed.ncbi.nlm.nih.gov/20584908" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" }, { "database": "PubMed", "id": "27995898", "url": "https://pubmed.ncbi.nlm.nih.gov/27995898" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 70, "end_pos": 70, "sequence_org": "S", "sequence_mut": "A", "comment": "Highly decreases interaction with ITPR1. No effect on phosphorylation. No effect on interaction with SLC4A4. Abolishes interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 71, "end_pos": 71, "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes interaction with ITPR1. Highly decreases phosphorylation. Abolishes interaction with SLC4A4. Abolishes interaction with FIP1L1. Highly decreases interaction with SLC9A3; when associated with A-68 and A-74.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "20584908", "url": "https://pubmed.ncbi.nlm.nih.gov/20584908" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 72, "end_pos": 72, "sequence_org": "T", "sequence_mut": "A", "comment": "Highly decreases interaction with ITPR1. Slightly increases phosphorylation. No effect on interaction with SLC4A4. Highly decreases interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 74, "end_pos": 74, "sequence_org": "S", "sequence_mut": "G", "comment": "Abolishes interaction with ITPR1. Slightly decreases phosphorylation. Strongly decreases interaction with SLC4A4. Abolishes interaction with FIP1L1. Highly decreases interaction with SLC9A3; when associated with A-68 and A-71.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "20584908", "url": "https://pubmed.ncbi.nlm.nih.gov/20584908" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 76, "end_pos": 76, "sequence_org": "S", "sequence_mut": "G", "comment": "No effect on interaction with ITPR1. No effect on phosphorylation. No effect on interaction with SLC4A4. No effect on interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 77, "end_pos": 77, "sequence_org": "S", "sequence_mut": "A", "comment": "Highly decreases interaction with ITPR1. Slightly decreases phosphorylation. Strongly decreases interaction with SLC4A4. Abolishes interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 80, "end_pos": 80, "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on interaction with SLC4A4. Highly decreases interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 82, "end_pos": 82, "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on interaction with ITPR1. No effect on phosphorylation. No effect on interaction with SLC4A4. Decreases interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 84, "end_pos": 84, "sequence_org": "S", "sequence_mut": "A", "comment": "Slightly decreases interaction with ITPR1. No effect on phosphorylation. No effect on interaction with SLC4A4. Decreases interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 85, "end_pos": 85, "sequence_org": "S", "sequence_mut": "A", "comment": "Slightly decreases interaction with ITPR1. No effect on phosphorylation. No effect on interaction with SLC4A4. Decreases interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 90, "end_pos": 90, "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on interaction with ITPR1. No effect on phosphorylation. No effect on interaction with SLC4A4. No effect on interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 97, "end_pos": 97, "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on interaction with ITPR1. No effect on interaction with SLC4A4. No effect on interaction with FIP1L1.", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16769890", "url": "https://pubmed.ncbi.nlm.nih.gov/16769890" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19224921", "url": "https://pubmed.ncbi.nlm.nih.gov/19224921" } ], "uniprot_canonical_ac": "O43865-1" } ], "phosphorylation": [ { "start_pos": 68, "end_pos": 68, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19220705", "url": "https://pubmed.ncbi.nlm.nih.gov/19220705" }, { "database": "PubMed", "id": "27995898", "url": "https://pubmed.ncbi.nlm.nih.gov/27995898" }, { "database": "iPTMnet", "id": "O43865", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O43865" }, { "database": "PubMed", "id": "27279487", "url": "https://pubmed.ncbi.nlm.nih.gov/27279487" } ], "site_lbl": "Ser68", "uniprot_canonical_ac": "O43865-1" }, { "start_pos": 71, "end_pos": 71, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "O43865", "url": "https://www.uniprot.org/uniprotkb/O43865" }, { "database": "PubMed", "id": "16793548", "url": "https://pubmed.ncbi.nlm.nih.gov/16793548" }, { "database": "PubMed", "id": "19220705", "url": "https://pubmed.ncbi.nlm.nih.gov/19220705" }, { "database": "PubMed", "id": "27995898", "url": "https://pubmed.ncbi.nlm.nih.gov/27995898" }, { "database": "iPTMnet", "id": "O43865", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O43865" } ], "site_lbl": "Ser71", "uniprot_canonical_ac": "O43865-1" } ], "record_id": "pubmed.16793548", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Inositol 1,4,5-trisphosphate receptor type 1 phosphorylation and regulation by extracellular signal-regulated kinase.", "journal": "Biochemical and biophysical research communications", "date": "2006", "authors": "Bai GR, Yang LH, Huang XY, Sun FZ", "reference": { "type": "PubMed", "id": "16925983", "url": "https://pubmed.ncbi.nlm.nih.gov/16925983" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11881-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "Itpr1", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1774, "end_pos": 1774, "kinase_uniprot_canonical_ac": "P28482-1", "kinase_gene_name": "MAPK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14643" }, { "database": "PubMed", "id": "16925983", "url": "https://pubmed.ncbi.nlm.nih.gov/16925983" } ], "site_lbl": "Ser1774", "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 436, "end_pos": 436, "kinase_uniprot_canonical_ac": "P28482-1", "kinase_gene_name": "MAPK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14643", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14643" }, { "database": "PubMed", "id": "16925983", "url": "https://pubmed.ncbi.nlm.nih.gov/16925983" } ], "site_lbl": "Ser436", "uniprot_canonical_ac": "Q14643-1" }, { "start_pos": 436, "end_pos": 436, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P11881", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P11881" }, { "database": "PubMed", "id": "16925983", "url": "https://pubmed.ncbi.nlm.nih.gov/16925983" } ], "site_lbl": "Ser436", "uniprot_canonical_ac": "P11881-1" } ], "record_id": "pubmed.16925983", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation.", "journal": "Blood", "date": "2007", "authors": "Antl M, von Bruhl ML, Eiglsperger C, Werner M, Konrad I, Kocher T, Wilm M, Hofmann F, Massberg S, Schlossmann J", "reference": { "type": "PubMed", "id": "16990611", "url": "https://pubmed.ncbi.nlm.nih.gov/16990611" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6F6-9", "protein_name": "Inositol 1,4,5-triphosphate receptor associated 1", "gene_name": "IRAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y691-1", "protein_name": "Calcium-activated potassium channel subunit beta-2", "gene_name": "KCNMB2", "tax_name": "Human" }, { 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glycosylation.", "journal": "The Journal of neuroscience : the official journal of the Society for Neuroscience", "date": "2007", "authors": "Rengifo J, Gibson CJ, Winkler E, Collin T, Ehrlich BE", "reference": { "type": "PubMed", "id": "18077693", "url": "https://pubmed.ncbi.nlm.nih.gov/18077693" }, "referenced_glycans": [ { "glytoucan_ac": "G49108TO" } ], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { 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"type", "subtype", "site_category", "site_seq", "relation", "comment", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Total deletion and a missense mutation of ITPR1 in Japanese SCA15 families.", "journal": "Neurology", "date": "2008", "authors": "Hara K, Shiga A, Nozaki H, Mitsui J, Takahashi Y, Ishiguro H, Yomono H, Kurisaki H, Goto J, Ikeuchi T, Tsuji S, Nishizawa M, Onodera O", "reference": { "type": "PubMed", "id": "18579805", "url": "https://pubmed.ncbi.nlm.nih.gov/18579805" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Lipid activation of protein kinases.", "journal": "Journal of lipid research", "date": "2009", "authors": "Newton AC", "reference": { "type": "PubMed", "id": "19033211", "url": "https://pubmed.ncbi.nlm.nih.gov/19033211" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49619-1", "protein_name": "Diacylglycerol kinase gamma", "gene_name": "DGKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6T7-1", "protein_name": "Diacylglycerol kinase beta", "gene_name": "DGKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23743-1", "protein_name": "Diacylglycerol kinase alpha", "gene_name": "DGKA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13574-2", "protein_name": "Diacylglycerol kinase zeta", "gene_name": "DGKZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7LDG7-1", "protein_name": "RAS guanyl-releasing protein 2", "gene_name": "RASGRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24723-1", "protein_name": "Protein kinase C eta type", "gene_name": "PRKCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14571-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "ITPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05655-1", "protein_name": "Protein kinase C delta type", "gene_name": "PRKCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13507-2", "protein_name": "Short transient receptor potential channel 3", "gene_name": "TRPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02156-1", "protein_name": "Protein kinase C epsilon type", "gene_name": "PRKCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04759-1", "protein_name": "Protein kinase C theta type", "gene_name": "PRKCQ", "tax_name": 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"Diacylglycerol kinase epsilon", "gene_name": "DGKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14573-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "ITPR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y210-1", "protein_name": "Short transient receptor potential channel 6", "gene_name": "TRPC6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19033211", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "An IRBIT homologue lacks binding activity to inositol 1,4,5-trisphosphate receptor due to the unique N-terminal appendage.", "journal": "J. Neurochem.", "date": "2009", "authors": "Ando H, Mizutani A, Mikoshiba K", "reference": { "type": "PubMed", "id": "19220705", "url": "https://pubmed.ncbi.nlm.nih.gov/19220705" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q80SW1-1", "protein_name": "S-adenosylhomocysteine hydrolase-like protein 1", "gene_name": "Ahcyl1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q68FL4-1", "protein_name": "S-adenosylhomocysteine hydrolase-like protein 2", "gene_name": "Ahcyl2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HN2-1", "protein_name": "S-adenosylhomocysteine hydrolase-like protein 2", "gene_name": "AHCYL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43865-1", "protein_name": "S-adenosylhomocysteine hydrolase-like protein 1", "gene_name": "AHCYL1", "tax_name": "Human" } ], 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Biol. Chem.", "date": "2013", "authors": "Schulman JJ, Wright FA, Kaufmann T, Wojcikiewicz RJ", "reference": { "type": "PubMed", "id": "23884412", "url": "https://pubmed.ncbi.nlm.nih.gov/23884412" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q63269-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "Itpr3", "tax_name": "Rat" }, { "uniprot_canonical_ac": "P29995-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "Itpr2", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q9UMX3-1", "protein_name": "Bcl-2-related ovarian killer protein", "gene_name": "BOK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11881-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "Itpr1", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ITPR1 gene p.Val1553Met mutation in Russian family with mild Spinocerebellar ataxia.", "journal": "Cerebellum & ataxias", "date": "2016", "authors": "Shadrina MI, Shulskaya MV, Klyushnikov SA, Nikopensius T, Nelis M, Kivistik PA, Komar AA, Limborska SA, Illarioshkin SN, Slominsky PA", "reference": { "type": "PubMed", "id": "26770814", "url": "https://pubmed.ncbi.nlm.nih.gov/26770814" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens 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Mol. Brain Res.", "date": "1995", "authors": "Nucifora F C, Li S H, Danoff S, Ullrich A, Ross C A", "reference": { "type": "PubMed", "id": "7500840", "url": "https://pubmed.ncbi.nlm.nih.gov/7500840" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7500840", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The human type 1 inositol 1,4,5-trisphosphate receptor from T lymphocytes. Structure, localization, and tyrosine phosphorylation.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Harnick DJ, Jayaraman T, Ma Y, Mulieri P, Go LO, Marks AR", "reference": { "type": "PubMed", "id": "7852357", "url": "https://pubmed.ncbi.nlm.nih.gov/7852357" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7852357", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human inositol 1,4,5-trisphosphate type-1 receptor, InsP3R1: structure, function, regulation of expression and chromosomal localization.", "journal": "Biochem. J.", "date": "1994", "authors": "Yamada N, Makino Y, Clark R A, Pearson D W, Mattei M G, Gu\u00e9net J L, Ohama E, Fujino I, Miyawaki A, Furuichi T", "reference": { "type": "PubMed", "id": "7945203", "url": "https://pubmed.ncbi.nlm.nih.gov/7945203" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7945203", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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"uniprot_canonical_ac": "P56373-1", "protein_name": "P2X purinoceptor 3", "gene_name": "P2RX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51575-1", "protein_name": "P2X purinoceptor 1", "gene_name": "P2RX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL9-1", "protein_name": "P2X purinoceptor 2", "gene_name": "P2RX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D31-1", "protein_name": "Calcium release-activated calcium channel protein 1", "gene_name": "ORAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99571-1", "protein_name": "P2X purinoceptor 4", "gene_name": "P2RX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13507-2", "protein_name": "Short transient receptor potential channel 3", "gene_name": "TRPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99572-1", "protein_name": "P2X purinoceptor 7", "gene_name": "P2RX7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q61056-1", "protein_name": "Short transient receptor potential 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"Induction of inositol 1,4,5 trisphosphate receptor genes by ionizing radiation.", "journal": "Int. J. Radiat. Biol.", "date": "1996", "authors": "Yan J, Khanna K K, Lavin M F", "reference": { "type": "PubMed", "id": "8648241", "url": "https://pubmed.ncbi.nlm.nih.gov/8648241" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8648241", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "P2X1 purinoceptor in human platelets. Molecular cloning and functional characterization after heterologous expression.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Sun B, Li J, Okahara K, Kambayashi J", "reference": { "type": "PubMed", "id": "9565569", "url": "https://pubmed.ncbi.nlm.nih.gov/9565569" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15547-1", "protein_name": "P2X purinoceptor 6", "gene_name": "P2RX6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SN7-1", "protein_name": "Protein orai-2", "gene_name": "ORAI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13586-1", "protein_name": "Stromal interaction molecule 1", "gene_name": "STIM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14571-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "ITPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93086-6", "protein_name": "P2X purinoceptor 5", "gene_name": "P2RX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56373-1", "protein_name": "P2X purinoceptor 3", "gene_name": "P2RX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51575-1", "protein_name": "P2X purinoceptor 1", "gene_name": "P2RX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL9-1", "protein_name": "P2X purinoceptor 2", "gene_name": "P2RX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D31-1", "protein_name": "Calcium release-activated calcium channel protein 1", "gene_name": "ORAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99571-1", "protein_name": "P2X purinoceptor 4", "gene_name": "P2RX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13507-2", "protein_name": "Short transient receptor potential channel 3", "gene_name": "TRPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99572-1", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The extended protein kinase C superfamily.", "journal": "The Biochemical journal", "date": "1998", "authors": "Mellor H, Parker PJ", "reference": { "type": "PubMed", "id": "9601053", "url": "https://pubmed.ncbi.nlm.nih.gov/9601053" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49619-1", "protein_name": "Diacylglycerol kinase gamma", "gene_name": "DGKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6T7-1", "protein_name": "Diacylglycerol kinase beta", "gene_name": "DGKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23743-1", "protein_name": "Diacylglycerol kinase alpha", "gene_name": "DGKA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13574-2", "protein_name": "Diacylglycerol kinase zeta", "gene_name": "DGKZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7LDG7-1", "protein_name": "RAS guanyl-releasing protein 2", "gene_name": "RASGRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24723-1", "protein_name": "Protein kinase C eta type", "gene_name": "PRKCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14571-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "ITPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05655-1", "protein_name": "Protein kinase C delta type", "gene_name": "PRKCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13507-2", "protein_name": "Short transient receptor potential channel 3", "gene_name": "TRPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02156-1", "protein_name": "Protein kinase C epsilon type", "gene_name": "PRKCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04759-1", "protein_name": "Protein kinase C theta type", "gene_name": "PRKCQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52824-1", "protein_name": "Diacylglycerol kinase theta", "gene_name": "DGKQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5KSL6-1", "protein_name": "Diacylglycerol kinase kappa", "gene_name": "DGKK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95267-1", "protein_name": "RAS guanyl-releasing protein 1", "gene_name": "RASGRP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCX4-1", "protein_name": "Short transient receptor potential channel 7", "gene_name": "TRPC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75912-2", "protein_name": "Diacylglycerol kinase iota", "gene_name": "DGKI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16760-1", "protein_name": "Diacylglycerol kinase delta", "gene_name": "DGKD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XP1-1", "protein_name": "Diacylglycerol kinase eta", "gene_name": "DGKH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52429-1", "protein_name": "Diacylglycerol kinase epsilon", "gene_name": "DGKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14573-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "ITPR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y210-1", "protein_name": "Short transient receptor potential channel 6", "gene_name": "TRPC6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9601053", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol.", "journal": "Nature", "date": "1999", "authors": "Hofmann T, Obukhov AG, Schaefer M, Harteneck C, Gudermann T, Schultz G", "reference": { "type": "PubMed", "id": "9930701", "url": "https://pubmed.ncbi.nlm.nih.gov/9930701" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14643-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR1", "gene_name": "ITPR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15547-1", "protein_name": "P2X purinoceptor 6", "gene_name": "P2RX6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SN7-1", "protein_name": "Protein orai-2", "gene_name": "ORAI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13586-1", "protein_name": "Stromal interaction molecule 1", "gene_name": "STIM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49619-1", "protein_name": "Diacylglycerol kinase gamma", "gene_name": "DGKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6T7-1", "protein_name": "Diacylglycerol kinase beta", "gene_name": "DGKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23743-1", "protein_name": "Diacylglycerol kinase alpha", "gene_name": "DGKA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13574-2", "protein_name": "Diacylglycerol kinase zeta", "gene_name": "DGKZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7LDG7-1", "protein_name": "RAS guanyl-releasing protein 2", "gene_name": "RASGRP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24723-1", "protein_name": "Protein kinase C eta type", "gene_name": "PRKCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14571-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR2", "gene_name": "ITPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05655-1", "protein_name": "Protein kinase C delta type", "gene_name": "PRKCD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93086-6", "protein_name": "P2X purinoceptor 5", "gene_name": "P2RX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56373-1", "protein_name": "P2X purinoceptor 3", "gene_name": "P2RX3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51575-1", "protein_name": "P2X purinoceptor 1", "gene_name": "P2RX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL9-1", "protein_name": "P2X purinoceptor 2", "gene_name": "P2RX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96D31-1", "protein_name": "Calcium release-activated calcium channel protein 1", "gene_name": "ORAI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99571-1", "protein_name": "P2X purinoceptor 4", "gene_name": "P2RX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13507-2", "protein_name": "Short transient receptor potential channel 3", "gene_name": "TRPC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02156-1", "protein_name": "Protein kinase C epsilon type", "gene_name": "PRKCE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99572-1", "protein_name": "P2X purinoceptor 7", "gene_name": "P2RX7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04759-1", "protein_name": "Protein kinase C theta type", "gene_name": "PRKCQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52824-1", "protein_name": "Diacylglycerol kinase theta", "gene_name": "DGKQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5KSL6-1", "protein_name": "Diacylglycerol kinase kappa", "gene_name": "DGKK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95267-1", "protein_name": "RAS guanyl-releasing protein 1", "gene_name": "RASGRP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCX4-1", "protein_name": "Short transient receptor potential channel 7", "gene_name": "TRPC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75912-2", "protein_name": "Diacylglycerol kinase iota", "gene_name": "DGKI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16760-1", "protein_name": "Diacylglycerol kinase delta", "gene_name": "DGKD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XP1-1", "protein_name": "Diacylglycerol kinase eta", "gene_name": "DGKH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52429-1", "protein_name": "Diacylglycerol kinase epsilon", "gene_name": "DGKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14573-1", "protein_name": "Inositol 1,4,5-trisphosphate-gated calcium channel ITPR3", "gene_name": "ITPR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y210-1", "protein_name": "Short transient receptor potential channel 6", "gene_name": "TRPC6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14643", "url": "https://www.uniprot.org/uniprotkb/Q14643" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9930701", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 32 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Rogers MA, Langbein L, Winter H, Ehmann C, Praetzel S, Korn B, Schweizer J", "reference": { "type": "PubMed", "id": "11279113", "url": "https://pubmed.ncbi.nlm.nih.gov/11279113" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BYQ0-1", "protein_name": "Keratin-associated protein 9-8", "gene_name": "KRTAP9-8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR6-1", "protein_name": "Keratin-associated protein 3-3", "gene_name": "KRTAP3-3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR7-1", "protein_name": "Keratin-associated protein 3-2", "gene_name": "KRTAP3-2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR2-1", "protein_name": "Keratin-associated protein 4-5", "gene_name": "KRTAP4-5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C7H8-1", "protein_name": "Keratin-associated protein 2-3", "gene_name": "KRTAP2-3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07627-1", "protein_name": "Keratin-associated protein 1-1", "gene_name": "KRTAP1-1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR3-1", "protein_name": "Keratin-associated protein 4-4", "gene_name": "KRTAP4-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYQ9-1", "protein_name": "Keratin-associated protein 4-8", "gene_name": "KRTAP4-8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYT5-1", "protein_name": "Keratin-associated protein 2-2", "gene_name": "KRTAP2-2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYP8-1", "protein_name": "Keratin-associated protein 17-1", "gene_name": "KRTAP17-1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYU5-1", "protein_name": "Keratin-associated protein 2-1", "gene_name": "KRTAP2-1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYP9-1", "protein_name": "Keratin-associated protein 9-9", "gene_name": "KRTAP9-9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYQ5-1", "protein_name": "Keratin-associated protein 4-6", "gene_name": "KRTAP4-6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYQ7-1", "protein_name": "Keratin-associated protein 4-1", "gene_name": "KRTAP4-1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR8-1", "protein_name": "Keratin-associated protein 3-1", "gene_name": "KRTAP3-1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR9-1", "protein_name": "Keratin-associated protein 2-4", "gene_name": "KRTAP2-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR0-1", "protein_name": "Keratin-associated protein 4-7", "gene_name": "KRTAP4-7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYQ6-1", "protein_name": "Keratin-associated protein 4-11", "gene_name": "KRTAP4-11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C5Y4-1", "protein_name": "Keratin-associated protein 1-4", "gene_name": "KRTAP1-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUG1-1", "protein_name": "Keratin-associated protein 1-3", "gene_name": "KRTAP1-3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYS1-1", "protein_name": "Keratin-associated protein 1-5", "gene_name": "KRTAP1-5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYQ8-1", "protein_name": "Keratin-associated protein 4-9", "gene_name": "KRTAP4-9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR4-1", "protein_name": "Keratin-associated protein 4-3", "gene_name": "KRTAP4-3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYQ4-1", "protein_name": "Keratin-associated protein 9-2", "gene_name": "KRTAP9-2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQ66-1", "protein_name": "Keratin-associated protein 4-12", "gene_name": "KRTAP4-12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYR5-1", "protein_name": "Keratin-associated protein 4-2", "gene_name": "KRTAP4-2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYQ2-1", "protein_name": "Keratin-associated protein 9-4", "gene_name": "KRTAP9-4", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure, expression, and chromosome mapping of LATS2, a mammalian homologue of the Drosophila tumor suppressor gene lats/warts.", "journal": "Genomics", "date": "2000", "authors": "Yabuta N, Fujii T, Copeland NG, Gilbert DJ, Jenkins NA, Nishiguchi H, Endo Y, Toji S, Tanaka H, Nishimune Y, Nojima H", "reference": { "type": "PubMed", "id": "10673337", "url": "https://pubmed.ncbi.nlm.nih.gov/10673337" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRM7-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "LATS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7TSJ6-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "Lats2", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRM7", "url": "https://www.uniprot.org/uniprotkb/Q9NRM7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10673337", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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novel human protein kinase, kpm, that is homologous to warts/lats, a Drosophila tumor suppressor.", "journal": "Oncogene", "date": "2000", "authors": "Hori T, Takaori-Kondo A, Kamikubo Y, Uchiyama T", "reference": { "type": "PubMed", "id": "10871863", "url": "https://pubmed.ncbi.nlm.nih.gov/10871863" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRM7-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "LATS2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRM7", "url": "https://www.uniprot.org/uniprotkb/Q9NRM7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 697, "end_pos": 697, "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of kinase activity, autophosphorylation and tumor suppressor activity.", "evidence": [ { "database": "UniProtKB", "id": 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} ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The LATS2/KPM tumor suppressor is a negative regulator of the androgen receptor.", "journal": "Molecular endocrinology (Baltimore, Md.)", "date": "2004", "authors": "Powzaniuk M, McElwee-Witmer S, Vogel RL, Hayami T, Rutledge SJ, Chen F, Harada S, Schmidt A, Rodan GA, Freedman LP, Bai C", "reference": { "type": "PubMed", "id": "15131260", "url": "https://pubmed.ncbi.nlm.nih.gov/15131260" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRM7-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "LATS2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRM7", "url": "https://www.uniprot.org/uniprotkb/Q9NRM7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15131260", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1.", "journal": "Oncogene", "date": "2005", "authors": "Chan EH, Nousiainen M, Chalamalasetty RB, Schafer A, Nigg EA, Sillje HH", "reference": { "type": "PubMed", "id": "15688006", "url": "https://pubmed.ncbi.nlm.nih.gov/15688006" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRM7-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "LATS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07157-1", "protein_name": "Tight junction protein 1", "gene_name": "TJP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13043-1", "protein_name": "Serine/threonine-protein kinase 4", "gene_name": "STK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8S9-1", "protein_name": "MOB kinase activator 1A", "gene_name": "MOB1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B6-1", "protein_name": "Protein salvador homolog 1", "gene_name": "SAV1", 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0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural basis for protein-protein interactions in the 14-3-3 protein family.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2006", "authors": "Yang X, Lee WH, Sobott F, Papagrigoriou E, Robinson CV, Grossmann JG, Sundstrom M, Doyle DA, Elkins JM", "reference": { "type": "PubMed", "id": "17085597", "url": "https://pubmed.ncbi.nlm.nih.gov/17085597" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRM7-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "LATS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07157-1", "protein_name": "Tight junction protein 1", "gene_name": "TJP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13043-1", "protein_name": "Serine/threonine-protein kinase 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"protein_name": "14-3-3 protein theta", "gene_name": "YWHAQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61981-1", "protein_name": "14-3-3 protein gamma", "gene_name": "YWHAG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46937-1", "protein_name": "Transcriptional coactivator YAP1", "gene_name": "YAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZV5-1", "protein_name": "WW domain-containing transcription regulator protein 1", "gene_name": "WWTR1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRM7", "url": "https://www.uniprot.org/uniprotkb/Q9NRM7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17085597", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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transcriptional coactivation activity toward ERBB4. In YAP-4SA; prevents phosphorylation by LATS1 and LATS2, promoting retention in the nucleus; when associated with A-61; A-109; A-127 and A-164. No effect on phosphorylation by PRPK4.", "evidence": [ { "database": "UniProtKB", "id": "P46937", "url": "https://www.uniprot.org/uniprotkb/P46937" }, { "database": "PubMed", "id": "20048001", "url": "https://pubmed.ncbi.nlm.nih.gov/20048001" }, { "database": "PubMed", "id": "17974916", "url": "https://pubmed.ncbi.nlm.nih.gov/17974916" }, { "database": "PubMed", "id": "18158288", "url": "https://pubmed.ncbi.nlm.nih.gov/18158288" }, { "database": "PubMed", "id": "12807903", "url": "https://pubmed.ncbi.nlm.nih.gov/12807903" }, { "database": "PubMed", "id": "29695716", "url": "https://pubmed.ncbi.nlm.nih.gov/29695716" } ], "uniprot_canonical_ac": "P46937-1" }, { "start_pos": 129, "end_pos": 129, "sequence_org": "P", "sequence_mut": "D", "comment": "No effect on phosphorylation but loss of interaction with YWHAB.", "evidence": [ { "database": "UniProtKB", "id": "P46937", "url": "https://www.uniprot.org/uniprotkb/P46937" }, { "database": "PubMed", "id": "17974916", "url": 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"", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.", "journal": "Molecular biology of the cell", "date": "2011", "authors": "Paramasivam M, Sarkeshik A, Yates JR 3rd, Fernandes MJ, McCollum D", "reference": { "type": "PubMed", "id": "21832154", "url": "https://pubmed.ncbi.nlm.nih.gov/21832154" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRM7-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "LATS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07157-1", "protein_name": "Tight junction protein 1", "gene_name": "TJP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13043-1", "protein_name": "Serine/threonine-protein kinase 4", "gene_name": "STK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8S9-1", "protein_name": "MOB kinase activator 1A", "gene_name": "MOB1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B6-1", "protein_name": "Protein salvador homolog 1", "gene_name": "SAV1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13188-1", "protein_name": "Serine/threonine-protein kinase 3", "gene_name": "STK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UDY2-1", "protein_name": "Tight junction protein 2", "gene_name": "TJP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IX03-1", "protein_name": "Protein KIBRA", "gene_name": "WWC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75161-1", "protein_name": "Nephrocystin-4", "gene_name": "NPHP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42574-1", "protein_name": "Caspase-3", "gene_name": "CASP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14641-1", "protein_name": "Segment polarity protein dishevelled homolog DVL-2", "gene_name": "DVL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY63-1", "protein_name": "Angiomotin-like protein 1", "gene_name": "AMOTL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2J4-1", "protein_name": "Angiomotin-like protein 2", "gene_name": "AMOTL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95835-1", "protein_name": 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"count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation.", "journal": "The EMBO journal", "date": "2012", "authors": "Zhang K, Rodriguez-Aznar E, Yabuta N, Owen RJ, Mingot JM, Nojima H, Nieto MA, Longmore GD", "reference": { "type": "PubMed", "id": "21952048", "url": "https://pubmed.ncbi.nlm.nih.gov/21952048" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRM7-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "LATS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "B0S8I4-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "lats2", "tax_name": "Zebrafish" }, { "uniprot_canonical_ac": "O95863-1", "protein_name": "Zinc finger protein SNAI1", "gene_name": "SNAI1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRM7", "url": "https://www.uniprot.org/uniprotkb/Q9NRM7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1041, "end_pos": 1041, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q9NRM7", "url": "https://www.uniprot.org/uniprotkb/Q9NRM7" }, { "database": "PubMed", "id": "21952048", "url": "https://pubmed.ncbi.nlm.nih.gov/21952048" }, { "database": "IntAct", "id": "Q9NRM7", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q9NRM7*" }, { "database": "iPTMnet", "id": "Q9NRM7", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q9NRM7" }, { "database": "PubMed", "id": "21832154", "url": "https://pubmed.ncbi.nlm.nih.gov/21832154" }, { "database": "PubMed", "id": "30154411", "url": "https://pubmed.ncbi.nlm.nih.gov/30154411" }, { "database": "PubMed", "id": "31669263", "url": "https://pubmed.ncbi.nlm.nih.gov/31669263" } ], "site_lbl": "Thr1041", "uniprot_canonical_ac": "Q9NRM7-1" }, { "start_pos": 203, "end_pos": 203, "kinase_uniprot_canonical_ac": "Q9NRM7-1", "kinase_gene_name": "LATS2", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O95863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O95863" }, { "database": "PubMed", "id": "21952048", "url": "https://pubmed.ncbi.nlm.nih.gov/21952048" } ], "site_lbl": "Thr203", "uniprot_canonical_ac": "O95863-1" }, { "start_pos": 203, "end_pos": 203, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by LATS2", "evidence": [ { "database": "UniProtKB", "id": "O95863", "url": "https://www.uniprot.org/uniprotkb/O95863" }, { "database": "IntAct", "id": "O95863", "url": "https://www.ebi.ac.uk/intact/interactors/id:O95863*" }, { "database": "iPTMnet", "id": "O95863", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O95863" }, { "database": "PubMed", "id": "21952048", "url": "https://pubmed.ncbi.nlm.nih.gov/21952048" }, { 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[] } ] }, { "title": "Mir-629 Repressed LATS2 Expression and Promoted the Proliferation of Prostate Cancer Cells.", "journal": "Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme", "date": "2023-08", "authors": "Li Yuqiao, Zeng Sha, Cao Longbin", "reference": { "type": "PubMed", "id": "36990459", "url": "https://pubmed.ncbi.nlm.nih.gov/36990459" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NRM7-1", "protein_name": "Serine/threonine-protein kinase LATS2", "gene_name": "LATS2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NRM7", "url": "https://www.uniprot.org/uniprotkb/Q9NRM7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36990459", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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