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Muscular Dystrophy Overlapping Marinesco-Sjogren Syndrome and Dystroglycanopathy.", "journal": "American journal of human genetics", "date": "2017", "authors": "Osborn DPS, Pond HL, Mazaheri N, Dejardin J, Munn CJ, Mushref K, Cauley ES, Moroni I, Pasanisi MB, Sellars EA, Hill RS, Partlow JN, Willaert RK, Bharj J, Malamiri RA, Galehdari H, Shariati G, Maroofian R, Mora M, Swan LE, Voit T, Conti FJ, Jamshidi Y, Manzini MC", "reference": { "type": "PubMed", "id": "28190459", "url": "https://pubmed.ncbi.nlm.nih.gov/28190459" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BT40-1", "protein_name": "Inositol polyphosphate 5-phosphatase K", "gene_name": "INPP5K", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0A8M3AHJ9-1", "protein_name": "Inositol polyphosphate 5-phosphatase Ka isoform X1", "gene_name": "inpp5ka", "tax_name": "Zebrafish" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BT40", "url": "https://www.uniprot.org/uniprotkb/Q9BT40" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 310, "end_pos": 310, "sequence_org": "D", "sequence_mut": "G", "comment": "No phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9BT40", "url": "https://www.uniprot.org/uniprotkb/Q9BT40" }, { "database": "PubMed", "id": "28190456", "url": "https://pubmed.ncbi.nlm.nih.gov/28190456" }, { "database": "PubMed", "id": "28190459", "url": "https://pubmed.ncbi.nlm.nih.gov/28190459" } ], "uniprot_canonical_ac": "Q9BT40-1" } ], "record_id": "pubmed.28190459", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "INPP5K and Atlastin-1 maintain the nonuniform distribution of ER-plasma membrane contacts in neurons.", "journal": "Life science alliance", "date": "2021", "authors": "Sun J, Harion R, Naito T, Saheki Y", "reference": { "type": "PubMed", "id": "34556534", "url": "https://pubmed.ncbi.nlm.nih.gov/34556534" }, "referenced_glycans": [], "referenced_proteins": [ { 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"evidence": [ { "database": "UniProtKB", "id": "Q9BT40", "url": "https://www.uniprot.org/uniprotkb/Q9BT40" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36599086", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 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"p50(cdc37) is a nonexclusive Hsp90 cohort which participates intimately in Hsp90-mediated folding of immature kinase molecules.", "journal": "Biochemistry", "date": "2000", "authors": "Hartson S D, Irwin A D, Shao J, Scroggins B T, Volk L, Huang W, Matts R L", "reference": { "type": "PubMed", "id": "10858314", "url": "https://pubmed.ncbi.nlm.nih.gov/10858314" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10858314", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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Biol. Chem.", "date": "2001", "authors": "Shao J, Grammatikakis N, Scroggins B T, Uma S, Huang W, Chen J J, Hartson S D, Matts R L", "reference": { "type": "PubMed", "id": "11036079", "url": "https://pubmed.ncbi.nlm.nih.gov/11036079" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQI3-1", "protein_name": "Eukaryotic translation initiation factor 2-alpha kinase 1", "gene_name": "EIF2AK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11036079", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional interaction of human Cdc37 with the androgen receptor but not with the glucocorticoid receptor.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Rao J, Lee P, Benzeno S, Cardozo C, Albertus J, Robins D M, Caplan A J", "reference": { "type": "PubMed", "id": "11085988", "url": "https://pubmed.ncbi.nlm.nih.gov/11085988" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11085988", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "AEE788: a dual family epidermal growth factor receptor/ErbB2 and vascular endothelial growth factor receptor tyrosine kinase inhibitor with antitumor and antiangiogenic activity.", "journal": "Cancer research", "date": "2004", "authors": "Traxler P, Allegrini PR, Brandt R, Brueggen J, Cozens R, Fabbro D, Grosios K, Lane HA, McSheehy P, Mestan J, Meyer T, Tang C, Wartmann M, Wood J, Caravatti G", "reference": { "type": "PubMed", "id": "15256466", "url": "https://pubmed.ncbi.nlm.nih.gov/15256466" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05209-1", 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"journal": "Cancer research", "date": "2004", "authors": "Wood ER, Truesdale AT, McDonald OB, Yuan D, Hassell A, Dickerson SH, Ellis B, Pennisi C, Horne E, Lackey K, Alligood KJ, Rusnak DW, Gilmer TM, Shewchuk L", "reference": { "type": "PubMed", "id": "15374980", "url": "https://pubmed.ncbi.nlm.nih.gov/15374980" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05209-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 12", "gene_name": "PTPN12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" 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"uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N5C8-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3", "gene_name": "TAB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYJ8-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2", "gene_name": "TAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15294-1", "protein_name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "gene_name": "OGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14254-1", "protein_name": "Flotillin-2", "gene_name": "FLOT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB16-1", "protein_name": "Mixed lineage kinase domain-like protein", "gene_name": "MLKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75955-1", "protein_name": "Flotillin-1", "gene_name": "FLOT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00560-1", "protein_name": "Syntenin-1", "gene_name": "SDCBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16282325", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 49 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Inhibition of the T790M gatekeeper mutant of the epidermal growth factor receptor by EXEL-7647.", "journal": "Clinical cancer research : an official journal of the American Association for Cancer Research", "date": "2007", "authors": "Gendreau SB, Ventura R, Keast P, Laird AD, Yakes FM, Zhang W, Bentzien F, Cancilla B, Lutman J, Chu F, Jackman L, Shi Y, Yu P, Wang J, Aftab DT, Jaeger CT, Meyer SM, De Costa A, Engell K, Chen J, Martini JF, Joly AH", "reference": { "type": "PubMed", "id": "17575237", "url": "https://pubmed.ncbi.nlm.nih.gov/17575237" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05209-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 12", "gene_name": "PTPN12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RT1-1", "protein_name": "Erbin", "gene_name": "ERBIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17575237", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cleavage of RIP3 inactivates its caspase-independent apoptosis pathway by removal of kinase domain.", "journal": "Cellular signalling", "date": "2007", "authors": "Feng S, Yang Y, Mei Y, Ma L, Zhu DE, Hoti N, Castanares M, Wu M", "reference": { "type": "PubMed", "id": "17644308", "url": "https://pubmed.ncbi.nlm.nih.gov/17644308" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FA3-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog 1", "gene_name": "PELI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60260-1", "protein_name": "E3 ubiquitin-protein ligase parkin", "gene_name": "PRKN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15294-1", "protein_name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "gene_name": "OGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14254-1", "protein_name": "Flotillin-2", "gene_name": "FLOT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB16-1", "protein_name": "Mixed lineage kinase domain-like protein", "gene_name": "MLKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75955-1", "protein_name": "Flotillin-1", "gene_name": "FLOT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00560-1", "protein_name": "Syntenin-1", "gene_name": "SDCBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17644308", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, 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"uniprot_canonical_ac": "Q7Z6E9-1", "protein_name": "E3 ubiquitin-protein ligase RBBP6", "gene_name": "RBBP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYL9-1", "protein_name": "Tropomodulin-3", "gene_name": "TMOD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43396-1", "protein_name": "Thioredoxin-like protein 1", "gene_name": "TXNL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76074-1", "protein_name": "cGMP-specific 3',5'-cyclic phosphodiesterase", "gene_name": "PDE5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40227-1", "protein_name": "T-complex protein 1 subunit zeta", "gene_name": "CCT6A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38159-1", "protein_name": "RNA-binding motif protein, X chromosome", "gene_name": "RBMX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", 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"uniprot_canonical_ac": "O00560-1", "protein_name": "Syntenin-1", "gene_name": "SDCBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26866270", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3.", "journal": "Nature cell biology", "date": "2016", "authors": "Seo J, Lee EW, Sung H, Seong D, Dondelinger Y, Shin J, Jeong M, Lee HK, Kim JH, Han SY, Lee C, Seong JK, Vandenabeele P, Song J", "reference": { "type": "PubMed", "id": "26900751", "url": "https://pubmed.ncbi.nlm.nih.gov/26900751" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced 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"gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60260-1", "protein_name": "E3 ubiquitin-protein ligase parkin", "gene_name": "PRKN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15294-1", "protein_name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "gene_name": "OGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14254-1", "protein_name": "Flotillin-2", "gene_name": "FLOT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB16-1", "protein_name": "Mixed lineage kinase domain-like protein", "gene_name": "MLKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75955-1", "protein_name": "Flotillin-1", "gene_name": "FLOT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00560-1", "protein_name": "Syntenin-1", "gene_name": "SDCBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "An Inducible Retroviral Expression System for Tandem Affinity Purification Mass-Spectrometry-Based Proteomics Identifies Mixed Lineage Kinase Domain-like Protein (MLKL) as an Heat Shock Protein 90 (HSP90) Client.", "journal": "Molecular & cellular proteomics : MCP", "date": "2016", "authors": "Bigenzahn JW, Fauster A, Rebsamen M, Kandasamy RK, Scorzoni S, Vladimer GI, Muller AC, Gstaiger M, Zuber J, Bennett KL, Superti-Furga G", "reference": { "type": "PubMed", "id": "26933192", "url": "https://pubmed.ncbi.nlm.nih.gov/26933192" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting 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"common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 284, "end_pos": 284, "sequence_org": "Y", "sequence_mut": "D", "comment": "Results in severely decreased interaction with CUL3. No effect on interaction with MSI2.", "evidence": [ { "database": "UniProtKB", "id": "Q9BYZ6", "url": "https://www.uniprot.org/uniprotkb/Q9BYZ6" }, { "database": "PubMed", "id": "29768694", "url": "https://pubmed.ncbi.nlm.nih.gov/29768694" }, { "database": "PubMed", "id": "37165955", "url": "https://pubmed.ncbi.nlm.nih.gov/37165955" }, { "database": "PubMed", "id": "27941885", "url": "https://pubmed.ncbi.nlm.nih.gov/27941885" }, { "database": "PubMed", "id": "15107402", "url": "https://pubmed.ncbi.nlm.nih.gov/15107402" } ], "uniprot_canonical_ac": "Q9BYZ6-1" } ], "record_id": "pubmed.27941885", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 339, "end_pos": 339, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q16543", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q16543" }, { "database": "PubMed", "id": "28073914", "url": "https://pubmed.ncbi.nlm.nih.gov/28073914" } ], "site_lbl": "Ser339", "uniprot_canonical_ac": "Q16543-1" } ], "record_id": "pubmed.28073914", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"url": "https://pubmed.ncbi.nlm.nih.gov/28661484" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FA3-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog 1", "gene_name": "PELI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60260-1", "protein_name": "E3 ubiquitin-protein ligase parkin", "gene_name": "PRKN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15294-1", "protein_name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "gene_name": "OGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14254-1", "protein_name": "Flotillin-2", "gene_name": "FLOT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NB16-1", "protein_name": "Mixed lineage kinase domain-like protein", "gene_name": "MLKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75955-1", "protein_name": "Flotillin-1", "gene_name": "FLOT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00560-1", "protein_name": "Syntenin-1", "gene_name": "SDCBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.28661484", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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{ "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients.", "journal": "EMBO J.", "date": "2017", "authors": "Woodford MR, Sager RA, Marris E, Dunn DM, Blanden AR, Murphy RL, Rensing N, Shapiro O, Panaretou B, Prodromou C, Loh SN, Gutmann DH, Bourboulia D, Bratslavsky G, Wong M, Mollapour M", "reference": { "type": "PubMed", "id": "29127155", "url": "https://pubmed.ncbi.nlm.nih.gov/29127155" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15185-1", "protein_name": "Prostaglandin E synthase 3", "gene_name": "PTGES3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07901-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "Hsp90aa1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BK64-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "gene_name": "Ahsa1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q92574-1", "protein_name": "Hamartin", "gene_name": "TSC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9EP53-1", "protein_name": "Hamartin", "gene_name": "Tsc1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P53041-1", "protein_name": "Serine/threonine-protein phosphatase 5", "gene_name": "PPP5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95433-1", "protein_name": "Activator of 90 kDa heat shock protein ATPase homolog 1", "gene_name": "AHSA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11802-1", "protein_name": "Cyclin-dependent kinase 4", "gene_name": "CDK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49815-1", "protein_name": "Tuberin", "gene_name": "TSC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", 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"evidence": [ { "database": "UniProtKB", "id": "P07900", "url": "https://www.uniprot.org/uniprotkb/P07900" }, { "database": "PubMed", "id": "29127155", "url": "https://pubmed.ncbi.nlm.nih.gov/29127155" } ], "uniprot_canonical_ac": "P07900-1" }, { "start_pos": 47, "end_pos": 47, "sequence_org": "E", "sequence_mut": "A", "comment": "Strong ATP-binding. Strong interaction with HSF1, HIF1A, ERBB2, MET, KEAP1 and RHOBTB2. No effect on interaction with TSC1.", "evidence": [ { "database": "UniProtKB", "id": "P07900", "url": "https://www.uniprot.org/uniprotkb/P07900" }, { "database": "PubMed", "id": "26517842", "url": "https://pubmed.ncbi.nlm.nih.gov/26517842" }, { "database": "PubMed", "id": "29127155", "url": "https://pubmed.ncbi.nlm.nih.gov/29127155" } ], "uniprot_canonical_ac": "P07900-1" }, { "start_pos": 728, "end_pos": 732, "sequence_org": "MEEVD", "sequence_mut": "", "comment": "Loss of interaction with TSC1.", "evidence": [ { "database": "UniProtKB", "id": "P07900", "url": "https://www.uniprot.org/uniprotkb/P07900" }, { "database": "PubMed", "id": "29127155", "url": "https://pubmed.ncbi.nlm.nih.gov/29127155" } ], "uniprot_canonical_ac": "P07900-1" }, { "start_pos": 93, "end_pos": 93, "sequence_org": "D", "sequence_mut": "A", "comment": "Impaired ATP-binding. Strong interaction with HIF1A, MET, KEAP1 and RHOBTB2. Loss of interaction with HSF1 and ERBB2. Los of interaction with TSC1.", "evidence": [ { "database": "UniProtKB", "id": "P07900", "url": "https://www.uniprot.org/uniprotkb/P07900" }, { "database": "PubMed", "id": "26517842", "url": "https://pubmed.ncbi.nlm.nih.gov/26517842" }, { "database": "PubMed", "id": "29127155", "url": "https://pubmed.ncbi.nlm.nih.gov/29127155" } ], "uniprot_canonical_ac": "P07900-1" }, { "start_pos": 223, "end_pos": 223, "sequence_org": "Y", "sequence_mut": "E", "comment": "Phosphomimetic mutant. Increases the binding to HSP90AA1 resulting in TSC1 dissociation from HSP90AA1.", "evidence": [ { "database": "UniProtKB", "id": "O95433", "url": "https://www.uniprot.org/uniprotkb/O95433" }, { "database": "PubMed", "id": "29127155", "url": "https://pubmed.ncbi.nlm.nih.gov/29127155" } ], "uniprot_canonical_ac": "O95433-1" } ], "phosphorylation": [ { "start_pos": 223, "end_pos": 223, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by ABL", "evidence": [ { "database": "UniProtKB", "id": "O95433", "url": "https://www.uniprot.org/uniprotkb/O95433" }, { "database": "iPTMnet", "id": "O95433", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O95433" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "26235616", "url": "https://pubmed.ncbi.nlm.nih.gov/26235616" }, { "database": "PubMed", "id": "26693507", "url": 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0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation induced cochaperone unfolding promotes kinase recruitment and client class-specific Hsp90 phosphorylation.", "journal": "Nature communications", "date": "2018", "authors": "Bachman AB, Keramisanou D, Xu W, Beebe K, Moses MA, Vasantha Kumar MV, Gray G, Noor RE, van der Vaart A, Neckers L, Gelis I", "reference": { "type": "PubMed", "id": "29343704", "url": "https://pubmed.ncbi.nlm.nih.gov/29343704" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16543", "url": "https://www.uniprot.org/uniprotkb/Q16543" } ], 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], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 14 }, { "field": "total_sites", "count": 14 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 14 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 14 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 14 }, { "field": "exact_o_linked_sites", "count": 14 }, { "field": "exact_o_linked_glycan_sites", "count": 14 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.", "journal": "Cell chemical biology", "date": "2019", "authors": "McNamara DE, Dovey CM, Hale AT, Quarato G, Grace CR, Guibao CD, Diep J, Nourse A, Cai CR, Wu H, Kalathur RC, Green DR, York JD, Carette JE, Moldoveanu T", "reference": { "type": "PubMed", "id": "31031142", "url": "https://pubmed.ncbi.nlm.nih.gov/31031142" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FA3-1", "protein_name": "E3 ubiquitin-protein ligase pellino homolog 1", "gene_name": "PELI1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15294-1", "protein_name": "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit", "gene_name": "OGT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14254-1", "protein_name": "Flotillin-2", "gene_name": "FLOT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": 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ALIX-syntenin-1-mediated exocytosis protect the cell membrane from damage caused by necroptosis.", "journal": "Science signaling", "date": "2019", "authors": "Fan W, Guo J, Gao B, Zhang W, Ling L, Xu T, Pan C, Li L, Chen S, Wang H, Zhang J, Wang X", "reference": { "type": "PubMed", "id": "31138766", "url": "https://pubmed.ncbi.nlm.nih.gov/31138766" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16543-1", "protein_name": "Hsp90 co-chaperone Cdc37", "gene_name": "CDC37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FA3-1", 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homodimer inhibits PLEKHA7 expression to promote gastric cancer invasion and metastasis.", "journal": "Oncogene", "date": "2023-03", "authors": "Wu Yu-Yun, Xiao Yu-Feng, Tian Li-Xing, He Bing, Liu Jiao, Li Zhi-Bin, Yang Huan, Chen Yang, Luo Qiang, Li Bo-Sheng, Yang Shi-Ming", "reference": { "type": "PubMed", "id": "36823376", "url": "https://pubmed.ncbi.nlm.nih.gov/36823376" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6IQ23-1", "protein_name": "Pleckstrin homology domain-containing family A member 7", "gene_name": "PLEKHA7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q6IQ23", "url": "https://www.uniprot.org/uniprotkb/Q6IQ23" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36823376", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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"uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55273-1", "protein_name": "Cyclin-dependent kinase 4 inhibitor D", "gene_name": "CDKN2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51965-1", "protein_name": "Ubiquitin-conjugating enzyme E2 E1", "gene_name": "UBE2E1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C5Y9-1", "protein_name": "Histone H2A-Bbd type 1", "gene_name": "H2AB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16270-1", "protein_name": "Insulin-like growth factor-binding protein 7", "gene_name": "IGFBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTM1-1", "protein_name": "Histone H2A.J", "gene_name": "H2AJ", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93077-1", "protein_name": "Histone H2A type 1-C", "gene_name": "H2AC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11802-1", "protein_name": "Cyclin-dependent kinase 4", "gene_name": "CDK4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13042-1", "protein_name": "Cell division cycle protein 16 homolog", "gene_name": "CDC16", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38936-1", "protein_name": "Cyclin-dependent kinase inhibitor 1", "gene_name": "CDKN1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00534-1", "protein_name": "Cyclin-dependent kinase 6", "gene_name": "CDK6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM11-1", "protein_name": "Fizzy-related protein homolog", "gene_name": "FZR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42773-1", "protein_name": "Cyclin-dependent kinase 4 inhibitor C", "gene_name": "CDKN2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NHZ8-1", "protein_name": "Anaphase-promoting complex subunit CDC26", "gene_name": "CDC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71UI9-1", "protein_name": "Histone H2A.V", "gene_name": "H2AZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04908-1", "protein_name": "Histone H2A type 1-B/E", "gene_name": "H2AC4; H2AC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20671-1", "protein_name": "Histone H2A type 1-D", "gene_name": "H2AC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16777-1", "protein_name": "Histone H2A type 2-C", "gene_name": "H2AC20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6FI13-1", "protein_name": "Histone H2A type 2-A", "gene_name": "H2AC18; H2AC19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99878-1", "protein_name": "Histone H2A type 1-J", "gene_name": "H2AC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01100-1", "protein_name": "Protein c-Fos", "gene_name": "FOS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05412-1", "protein_name": "Transcription factor Jun", "gene_name": "JUN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95231-1", "protein_name": "Homeobox protein VENTX", "gene_name": "VENTX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UJX4", "url": "https://www.uniprot.org/uniprotkb/Q9UJX4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10432220", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] } ]