[ { "title": "Comparative studies on the substrate specificity of lecithin:cholesterol acyltransferase towards the molecular species of phosphatidylcholine in the plasma of 14 vertebrates.", "journal": "Journal of lipid research", "date": "1996-01", "authors": "Subbaiah P V, Liu M", "reference": { "type": "PubMed", "id": "8820107", "url": "https://pubmed.ncbi.nlm.nih.gov/8820107" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53760-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P16301-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "Lcat", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P30930-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Pig" }, { "uniprot_canonical_ac": "P18424-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "Lcat", "tax_name": "Rat" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8820107", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel missense mutation (Asn5-->Ile) in lecithin: cholesterol acyltransferase (LCAT) gene in a Japanese patient with LCAT deficiency.", "journal": "International journal of clinical & laboratory research", "date": "1996", "authors": "Okubo M, Aoyama Y, Shio H, Albers JJ, Murase T", "reference": { "type": "PubMed", "id": "9007616", "url": "https://pubmed.ncbi.nlm.nih.gov/9007616" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9007616", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular basis of fish-eye disease in a patient from Spain. Characterization of a novel mutation in the LCAT gene and lipid analysis of the cornea.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "1997", "authors": "Blanco-Vaca F, Qu SJ, Fiol C, Fan HZ, Pao Q, Marzal-Casacuberta A, Albers JJ, Hurtado I, Gracia V, Pinto X, Marti T, Pownall HJ", "reference": { "type": "PubMed", "id": "9261271", "url": "https://pubmed.ncbi.nlm.nih.gov/9261271" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9261271", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Characterization of recombinant human plasma lecithin: cholesterol acyltransferase (LCAT): N-linked carbohydrate structures and catalytic properties.", "journal": "Journal of lipid research", "date": "1998", "authors": "Lacko AG, Reason AJ, Nuckolls C, Kudchodkar BJ, Nair MP, Sundarrajan G, Pritchard PH, Morris HR, Dell A", "reference": { "type": "PubMed", "id": "9555945", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, "referenced_glycans": [ { "glytoucan_ac": "G90093AU" }, { "glytoucan_ac": "G72797UR" }, { "glytoucan_ac": "G20425TQ" }, { "glytoucan_ac": "G36191CD" }, { "glytoucan_ac": "G74286KY" }, { "glytoucan_ac": "G22388FD" }, { "glytoucan_ac": "G78059CC" }, { "glytoucan_ac": "G63889NK" }, { "glytoucan_ac": "G50045TK" }, { "glytoucan_ac": "G86357DX" }, { "glytoucan_ac": "G29857RC" }, { "glytoucan_ac": "G23863VK" } ], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "glycosylation": [ { "glytoucan_ac": "G20425TQ", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0010000.1100000000.010111000011111100.00010.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G22388FD", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0010000.1100000000.000000000001000000.10000.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G23863VK", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0100000.1110000000.010111100011111101.00010.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G29857RC", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0010000.1100000000.010100000001101000.10000.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G36191CD", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0100000.1100000000.010100000001111000.10000.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G50045TK", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0100000.1100000000.010111100011111101.00010.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G63889NK", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0010000.1110000000.000000000011111000.10000.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G72797UR", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0010000.1110000000.010111000011111101.00010.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G74286KY", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0010000.1110000000.000000000001000000.10000.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G78059CC", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0100000.1110000000.010100000001111000.10000.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G86357DX", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0010000.1110000000.010000000011111000.10000.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G90093AU", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "evidence": [ { "id": "9555945", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/9555945" }, { "id": "495", "database": "GlyConnect", "url": "https://glyconnect.expasy.org/browser/proteins/495" } ], "filter_code": "000000000000000000000.0000000.00010000000000.0010000.1110000000.010011000011111100.00010.01000", "uniprot_canonical_ac": "P04180-1" } ], "glycan_expression": [ { "glytoucan_ac": "G90093AU", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G72797UR", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G20425TQ", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G36191CD", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G74286KY", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G22388FD", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G78059CC", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G63889NK", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G50045TK", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G86357DX", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G29857RC", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "G23863VK", "abundance": "", "tissue": { "name": "kidney", "namespace": "UBERON", "id": "0002113", "url": "http://purl.obolibrary.org/obo/UBERON_0002113" }, "species": { "name": "Homo sapiens", "taxid": 9606, "reference_species": "Homo sapiens [9606]", "common_name": "Human", "glygen_name": "Human" }, "cell_line": {}, "uniprot_canonical_ac": "P04180-1" } ], "record_id": "pubmed.9555945", "abstract": "", "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "glytoucan_ac" ] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 12 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 12 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 12 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 12 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 1 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 12 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_n_linked_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_n_linked_glycans", "count": 12 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Transmission of two novel mutations in a pedigree with familial lecithin:cholesterol acyltransferase deficiency: structure-function relationships and studies in a compound heterozygous proband.", "journal": "Journal of lipid research", "date": "1998", "authors": "Argyropoulos G, Jenkins A, Klein RL, Lyons T, Wagenhorst B, St Armand J, Marcovina SM, Albers JJ, Pritchard PH, Garvey WT", "reference": { "type": "PubMed", "id": "9741700", "url": "https://pubmed.ncbi.nlm.nih.gov/9741700" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9741700", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The gene CSTF2T, encoding the human variant CstF-64 polyadenylation protein CstF-64, lacks introns and may be associated with male sterility.", "journal": "Genomics", "date": "2002", "authors": "Dass B, McDaniel L, Schultz RA, Attaya E, MacDonald CC", "reference": { "type": "PubMed", "id": "12408968", "url": "https://pubmed.ncbi.nlm.nih.gov/12408968" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0L4-1", "protein_name": "Cleavage stimulation factor subunit 2 tau variant", "gene_name": "CSTF2T", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8HXM1-1", "protein_name": "Cleavage stimulation factor subunit 2", "gene_name": "CSTF2", "tax_name": "Bovine" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H0L4", "url": "https://www.uniprot.org/uniprotkb/Q9H0L4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12408968", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein.", "journal": "The EMBO journal", "date": "2003", "authors": "Perez Canadillas JM, Varani G", "reference": { "type": "PubMed", "id": "12773396", "url": "https://pubmed.ncbi.nlm.nih.gov/12773396" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0L4-1", "protein_name": "Cleavage stimulation factor subunit 2 tau variant", "gene_name": "CSTF2T", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33240-1", "protein_name": "Cleavage stimulation factor subunit 2", "gene_name": "CSTF2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H0L4", "url": "https://www.uniprot.org/uniprotkb/Q9H0L4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12773396", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "sCLIP-an integrated platform to study RNA-protein interactomes in biomedical research: identification of CSTF2tau in alternative processing of small nuclear RNAs.", "journal": "Nucleic acids research", "date": "2017", "authors": "Kargapolova Y, Levin M, Lackner K, Danckwardt S", "reference": { "type": "PubMed", "id": "28334977", "url": "https://pubmed.ncbi.nlm.nih.gov/28334977" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0L4-1", "protein_name": "Cleavage stimulation factor subunit 2 tau variant", "gene_name": "CSTF2T", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H0L4", "url": "https://www.uniprot.org/uniprotkb/Q9H0L4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.28334977", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CSTF2T up-regulates IGHG1 by binding to ZEB1 to promote melanoma cell proliferation, migration, and invasion.", "journal": "Tissue & cell", "date": "2023-04", "authors": "Li Yanfei, Yun Xia, Li Jiaojiao, Bai Meilin", "reference": { "type": "PubMed", "id": "36736099", "url": "https://pubmed.ncbi.nlm.nih.gov/36736099" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0L4-1", "protein_name": "Cleavage stimulation factor subunit 2 tau variant", "gene_name": "CSTF2T", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H0L4", "url": "https://www.uniprot.org/uniprotkb/Q9H0L4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36736099", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Angiopoietins 3 and 4: diverging gene counterparts in mice and humans.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1999", "authors": "Valenzuela DM, Griffiths JA, Rojas J, Aldrich TH, Jones PF, Zhou H, McClain J, Copeland NG, Gilbert DJ, Jenkins NA, Huang T, Papadopoulos N, Maisonpierre PC, Davis S, Yancopoulos GD", "reference": { "type": "PubMed", "id": "10051567", "url": "https://pubmed.ncbi.nlm.nih.gov/10051567" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9WVH6-1", "protein_name": "Angiopoietin-4", "gene_name": "Angpt4", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10051567", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanism of action and in vivo role of platelet-derived growth factor.", "journal": "Physiological reviews", "date": "1999", "authors": "Heldin CH, Westermark B", "reference": { "type": "PubMed", "id": "10508235", "url": "https://pubmed.ncbi.nlm.nih.gov/10508235" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53420-1", "protein_name": "Collagen alpha-4(IV) chain", "gene_name": "COL4A4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09958-1", "protein_name": "Furin", "gene_name": "FURIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZP0-1", "protein_name": "Platelet-derived growth factor D", "gene_name": "PDGFD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05209-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 12", "gene_name": "PTPN12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07996-1", "protein_name": "Thrombospondin-1", "gene_name": "THBS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10451-1", "protein_name": "Osteopontin", "gene_name": "SPP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12110-1", "protein_name": "Collagen alpha-2(VI) chain", "gene_name": "COL6A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20908-1", "protein_name": "Collagen alpha-1(V) chain", "gene_name": "COL5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02462-1", "protein_name": "Collagen alpha-1(IV) chain", "gene_name": "COL4A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08572-1", "protein_name": "Collagen alpha-2(IV) chain", "gene_name": "COL4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20849-1", "protein_name": "Collagen alpha-1(IX) chain", "gene_name": "COL9A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25940-1", "protein_name": "Collagen alpha-3(V) chain", "gene_name": "COL5A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01955-1", "protein_name": "Collagen alpha-3(IV) chain", "gene_name": "COL4A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35442-1", "protein_name": "Thrombospondin-2", "gene_name": "THBS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35443-1", "protein_name": "Thrombospondin-4", "gene_name": "THBS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00747-1", "protein_name": "Plasminogen", "gene_name": "PLG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02461-1", "protein_name": "Collagen alpha-1(III) chain", "gene_name": "COL3A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29400-1", "protein_name": "Collagen alpha-5(IV) chain", "gene_name": "COL4A5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14055-1", "protein_name": "Collagen alpha-2(IX) chain", "gene_name": "COL9A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8TX70-1", "protein_name": "Collagen alpha-5(VI) chain", "gene_name": "COL6A5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05997-1", "protein_name": "Collagen alpha-2(V) chain", "gene_name": "COL5A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NMZ7-1", "protein_name": "Collagen alpha-6(VI) chain", "gene_name": "COL6A6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12111-1", "protein_name": "Collagen alpha-3(VI) chain", "gene_name": "COL6A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12109-1", "protein_name": "Collagen alpha-1(VI) chain", "gene_name": "COL6A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02458-2", "protein_name": "Collagen alpha-1(II) chain", "gene_name": "COL2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14050-1", "protein_name": "Collagen alpha-3(IX) chain", "gene_name": "COL9A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49746-1", "protein_name": "Thrombospondin-3", "gene_name": "THBS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00750-1", "protein_name": "Tissue-type plasminogen activator", "gene_name": "PLAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10508235", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 54 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of Tek/Tie2 binding partners. Binding to a multifunctional docking site mediates cell survival and migration.", "journal": "The Journal of biological chemistry", "date": "1999", "authors": "Jones N, Master Z, Jones J, Bouchard D, Gunji Y, Sasaki H, Daly R, Alitalo K, Dumont DJ", "reference": { "type": "PubMed", "id": "10521483", "url": "https://pubmed.ncbi.nlm.nih.gov/10521483" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03160-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "Grb7", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLM9-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "Grb14", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q02858-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "Tek", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P26450-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "Pik3r1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q60631-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "Grb2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35235-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "Ptpn11", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1102, "end_pos": 1102, "kinase_uniprot_canonical_ac": "Q02763-1", "kinase_gene_name": "TEK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q02763", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02763" }, { "database": "PubMed", "id": "10521483", "url": "https://pubmed.ncbi.nlm.nih.gov/10521483" }, { "database": "PubMed", "id": "9632797", "url": "https://pubmed.ncbi.nlm.nih.gov/9632797" }, { "database": "PubMed", "id": "20973951", "url": "https://pubmed.ncbi.nlm.nih.gov/20973951" }, { "database": "UniProtKB", "id": "Q02763", "url": "https://www.uniprot.org/uniprotkb/Q02763" }, { "database": "PubMed", "id": "14665640", "url": "https://pubmed.ncbi.nlm.nih.gov/14665640" } ], "site_lbl": "Tyr1102", "uniprot_canonical_ac": "Q02763-1" }, { "start_pos": 1100, "end_pos": 1100, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q02858", "url": "https://www.uniprot.org/uniprotkb/Q02858" }, { "database": "IntAct", "id": "Q02858", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q02858*" }, { "database": "iPTMnet", "id": "Q02858", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02858" }, { "database": "PubMed", "id": "10521483", "url": "https://pubmed.ncbi.nlm.nih.gov/10521483" }, { "database": "PubMed", "id": "9632797", "url": "https://pubmed.ncbi.nlm.nih.gov/9632797" } ], "site_lbl": "Tyr1100", "uniprot_canonical_ac": "Q02858-1" } ], "mutagenesis": [ { "start_pos": 1100, "end_pos": 1100, "sequence_org": "Y", "sequence_mut": "F", "comment": "Reduced levels of autophosphorylation. Abolishes interaction with GRB2 and GRB7. Abolishes phosphorylation of GRB7 and PIK3R1.", "evidence": [ { "database": "UniProtKB", "id": "Q02858", "url": "https://www.uniprot.org/uniprotkb/Q02858" }, { "database": "PubMed", "id": "10521483", "url": "https://pubmed.ncbi.nlm.nih.gov/10521483" }, { "database": "PubMed", "id": "9632797", "url": "https://pubmed.ncbi.nlm.nih.gov/9632797" }, { "database": "PubMed", "id": "12665569", "url": "https://pubmed.ncbi.nlm.nih.gov/12665569" } ], "uniprot_canonical_ac": "Q02858-1" } ], "record_id": "pubmed.10521483", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Role of Grb7 targeting to focal contacts and its phosphorylation by focal adhesion kinase in regulation of cell migration.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Han DC, Shen TL, Guan JL", "reference": { "type": "PubMed", "id": "10893408", "url": "https://pubmed.ncbi.nlm.nih.gov/10893408" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10893408", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tek/Tie2 signaling: new and old partners.", "journal": "Cancer metastasis reviews", "date": "2000", "authors": "Jones N, Dumont DJ", "reference": { "type": "PubMed", "id": "11191051", "url": "https://pubmed.ncbi.nlm.nih.gov/11191051" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11191051", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Angiopoietin-1, unlike angiopoietin-2, is incorporated into the extracellular matrix via its linker peptide region.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Xu Y, Yu Q", "reference": { "type": "PubMed", "id": "11447223", "url": "https://pubmed.ncbi.nlm.nih.gov/11447223" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11447223", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Angiopoietin and Tie signaling pathways in vascular development.", "journal": "Matrix biology : journal of the International Society for Matrix Biology", "date": "2001", "authors": "Loughna S, Sato TN", "reference": { "type": "PubMed", "id": "11566266", "url": "https://pubmed.ncbi.nlm.nih.gov/11566266" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11566266", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Grb7 family proteins: structure, interactions with other signaling molecules and potential cellular functions.", "journal": "Oncogene", "date": "2001", "authors": "Han DC, Shen TL, Guan JL", "reference": { "type": "PubMed", "id": "11607834", "url": "https://pubmed.ncbi.nlm.nih.gov/11607834" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11607834", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak.", "journal": "The EMBO journal", "date": "2001", "authors": "Master Z, Jones N, Tran J, Jones J, Kerbel RS, Dumont DJ", "reference": { "type": "PubMed", "id": "11689432", "url": "https://pubmed.ncbi.nlm.nih.gov/11689432" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O70469-1", "protein_name": "Docking protein 2", "gene_name": "Dok2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 345, "end_pos": 345, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "O60496", "url": "https://www.uniprot.org/uniprotkb/O60496" }, { "database": "iPTMnet", "id": "O60496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60496" }, { "database": "PubMed", "id": "11689432", "url": "https://pubmed.ncbi.nlm.nih.gov/11689432" }, { "database": "PubMed", "id": "9764820", "url": "https://pubmed.ncbi.nlm.nih.gov/9764820" }, { "database": "IntAct", "id": "O60496", "url": "https://www.ebi.ac.uk/intact/interactors/id:O60496*" }, { "database": "PubMed", "id": "10428862", "url": "https://pubmed.ncbi.nlm.nih.gov/10428862" } ], "site_lbl": "Tyr345", "uniprot_canonical_ac": "O60496-1" }, { "start_pos": 351, "end_pos": 351, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "O70469", "url": "https://www.uniprot.org/uniprotkb/O70469" }, { "database": "PubMed", "id": "10508618", "url": "https://pubmed.ncbi.nlm.nih.gov/10508618" }, { "database": "IntAct", "id": "O70469", "url": "https://www.ebi.ac.uk/intact/interactors/id:O70469*" }, { "database": "iPTMnet", "id": "O70469", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O70469" }, { "database": "PubMed", "id": "11689432", "url": "https://pubmed.ncbi.nlm.nih.gov/11689432" } ], "site_lbl": "Tyr351", "uniprot_canonical_ac": "O70469-1" } ], "record_id": "pubmed.11689432", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The angiopoietins and Tie2/Tek: adding to the complexity of cardiovascular development.", "journal": "Seminars in cell & developmental biology", "date": "2002", "authors": "Ward NL, Dumont DJ", "reference": { "type": "PubMed", "id": "11969368", "url": "https://pubmed.ncbi.nlm.nih.gov/11969368" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11969368", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Association of Grb7 with phosphoinositides and its role in the regulation of cell migration.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Shen TL, Han DC, Guan JL", "reference": { "type": "PubMed", "id": "12021278", "url": "https://pubmed.ncbi.nlm.nih.gov/12021278" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05397-1", "protein_name": "Focal adhesion kinase 1", "gene_name": "PTK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00944-1", "protein_name": "Focal adhesion kinase 1", "gene_name": "PTK2", "tax_name": "Chicken" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 239, "end_pos": 239, "sequence_org": "R", "sequence_mut": "L", "comment": "Abolishes phosphoinositide binding.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "12021278", "url": "https://pubmed.ncbi.nlm.nih.gov/12021278" } ], "uniprot_canonical_ac": "Q14451-1" } ], "phosphorylation": [ { "start_pos": 397, "end_pos": 397, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q05397", "url": "https://www.uniprot.org/uniprotkb/Q05397" }, { "database": "iPTMnet", "id": "Q05397", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q05397" }, { "database": "PubMed", "id": "11314030", "url": "https://pubmed.ncbi.nlm.nih.gov/11314030" }, { "database": "PubMed", "id": "12370821", "url": "https://pubmed.ncbi.nlm.nih.gov/12370821" }, { "database": "PubMed", "id": "17016520", "url": "https://pubmed.ncbi.nlm.nih.gov/17016520" }, { "database": "PubMed", "id": "20068231", "url": "https://pubmed.ncbi.nlm.nih.gov/20068231" }, { "database": "PubMed", "id": "7509446", "url": "https://pubmed.ncbi.nlm.nih.gov/7509446" }, { "database": "PubMed", "id": "7529876", "url": "https://pubmed.ncbi.nlm.nih.gov/7529876" }, { "database": "IntAct", "id": "Q05397", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q05397*" }, { "database": "PubMed", "id": "27178753", "url": "https://pubmed.ncbi.nlm.nih.gov/27178753" }, { "database": "PRO", "id": "Q05397", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q05397" }, { "database": "PubMed", "id": "10047444", "url": "https://pubmed.ncbi.nlm.nih.gov/10047444" }, { "database": "PubMed", "id": "10212207", "url": "https://pubmed.ncbi.nlm.nih.gov/10212207" }, { "database": "PubMed", "id": "10400703", "url": "https://pubmed.ncbi.nlm.nih.gov/10400703" }, { "database": "PubMed", "id": "10672902", "url": "https://pubmed.ncbi.nlm.nih.gov/10672902" }, { "database": "PubMed", "id": "10769034", "url": "https://pubmed.ncbi.nlm.nih.gov/10769034" }, { "database": "PubMed", "id": "10816598", "url": "https://pubmed.ncbi.nlm.nih.gov/10816598" }, { "database": "PubMed", "id": "10856226", "url": "https://pubmed.ncbi.nlm.nih.gov/10856226" }, { "database": "PubMed", "id": "10958798", "url": "https://pubmed.ncbi.nlm.nih.gov/10958798" }, { "database": "PubMed", "id": "10998418", "url": "https://pubmed.ncbi.nlm.nih.gov/10998418" }, { "database": "PubMed", "id": "11027591", "url": "https://pubmed.ncbi.nlm.nih.gov/11027591" }, { "database": "PubMed", "id": "11119718", "url": "https://pubmed.ncbi.nlm.nih.gov/11119718" }, { "database": "PubMed", "id": "11149924", "url": "https://pubmed.ncbi.nlm.nih.gov/11149924" }, { "database": "PubMed", "id": "11278488", "url": "https://pubmed.ncbi.nlm.nih.gov/11278488" }, { "database": "PubMed", "id": "11313859", "url": "https://pubmed.ncbi.nlm.nih.gov/11313859" }, { "database": "PubMed", "id": "11438458", "url": "https://pubmed.ncbi.nlm.nih.gov/11438458" }, { "database": "PubMed", "id": "11448998", "url": "https://pubmed.ncbi.nlm.nih.gov/11448998" }, { "database": "PubMed", "id": "11572981", "url": "https://pubmed.ncbi.nlm.nih.gov/11572981" }, { "database": "PubMed", "id": "11585739", "url": "https://pubmed.ncbi.nlm.nih.gov/11585739" }, { "database": "PubMed", "id": "11602246", "url": "https://pubmed.ncbi.nlm.nih.gov/11602246" }, { "database": "PubMed", "id": "11606050", "url": "https://pubmed.ncbi.nlm.nih.gov/11606050" }, { "database": "PubMed", "id": "11668182", "url": "https://pubmed.ncbi.nlm.nih.gov/11668182" }, { "database": "PubMed", "id": "11696015", "url": "https://pubmed.ncbi.nlm.nih.gov/11696015" }, { "database": "PubMed", "id": "11787067", "url": "https://pubmed.ncbi.nlm.nih.gov/11787067" }, { "database": "PubMed", "id": "11807823", "url": "https://pubmed.ncbi.nlm.nih.gov/11807823" }, { "database": "PubMed", "id": "11891289", "url": "https://pubmed.ncbi.nlm.nih.gov/11891289" }, { "database": "PubMed", "id": "11909938", "url": "https://pubmed.ncbi.nlm.nih.gov/11909938" }, { "database": "PubMed", "id": "12021278", "url": "https://pubmed.ncbi.nlm.nih.gov/12021278" }, { "database": "PubMed", "id": "12084011", "url": "https://pubmed.ncbi.nlm.nih.gov/12084011" }, { "database": "PubMed", "id": "12215217", "url": "https://pubmed.ncbi.nlm.nih.gov/12215217" }, { "database": "PubMed", "id": "12370243", "url": "https://pubmed.ncbi.nlm.nih.gov/12370243" }, { "database": "PubMed", "id": "12391143", "url": "https://pubmed.ncbi.nlm.nih.gov/12391143" }, { "database": "PubMed", "id": "12558988", "url": "https://pubmed.ncbi.nlm.nih.gov/12558988" }, { "database": "PubMed", "id": "12615911", "url": "https://pubmed.ncbi.nlm.nih.gov/12615911" }, { "database": "PubMed", "id": "12640026", "url": "https://pubmed.ncbi.nlm.nih.gov/12640026" }, { "database": "PubMed", "id": "12700132", "url": "https://pubmed.ncbi.nlm.nih.gov/12700132" }, { "database": "PubMed", "id": "12730223", "url": "https://pubmed.ncbi.nlm.nih.gov/12730223" }, { "database": "PubMed", "id": "12738990", "url": "https://pubmed.ncbi.nlm.nih.gov/12738990" }, { "database": "PubMed", "id": "12761229", "url": "https://pubmed.ncbi.nlm.nih.gov/12761229" }, { "database": "PubMed", "id": "12838315", "url": "https://pubmed.ncbi.nlm.nih.gov/12838315" }, { "database": "PubMed", "id": "12871985", "url": "https://pubmed.ncbi.nlm.nih.gov/12871985" }, { "database": "PubMed", "id": "12876277", "url": "https://pubmed.ncbi.nlm.nih.gov/12876277" }, { "database": "PubMed", "id": "12876384", "url": "https://pubmed.ncbi.nlm.nih.gov/12876384" }, { "database": "PubMed", "id": "12927054", "url": "https://pubmed.ncbi.nlm.nih.gov/12927054" }, { "database": "PubMed", "id": "12960434", "url": "https://pubmed.ncbi.nlm.nih.gov/12960434" }, { "database": "PubMed", "id": "14500712", "url": "https://pubmed.ncbi.nlm.nih.gov/14500712" }, { "database": "PubMed", "id": "14603053", "url": "https://pubmed.ncbi.nlm.nih.gov/14603053" }, { "database": "PubMed", "id": "14604860", "url": "https://pubmed.ncbi.nlm.nih.gov/14604860" }, { "database": "PubMed", "id": "14610060", "url": "https://pubmed.ncbi.nlm.nih.gov/14610060" }, { "database": "PubMed", "id": "14666664", "url": "https://pubmed.ncbi.nlm.nih.gov/14666664" }, { "database": "PubMed", "id": "14670178", "url": "https://pubmed.ncbi.nlm.nih.gov/14670178" }, { "database": "PubMed", "id": "14703945", "url": "https://pubmed.ncbi.nlm.nih.gov/14703945" }, { "database": "PubMed", "id": "14712221", "url": "https://pubmed.ncbi.nlm.nih.gov/14712221" }, { "database": "PubMed", "id": "14761895", "url": "https://pubmed.ncbi.nlm.nih.gov/14761895" }, { "database": "PubMed", "id": "14978737", "url": "https://pubmed.ncbi.nlm.nih.gov/14978737" }, { "database": "PubMed", "id": "15126359", "url": "https://pubmed.ncbi.nlm.nih.gov/15126359" }, { "database": "PubMed", "id": "15138291", "url": "https://pubmed.ncbi.nlm.nih.gov/15138291" }, { "database": "PubMed", "id": "15210734", "url": "https://pubmed.ncbi.nlm.nih.gov/15210734" }, { "database": "PubMed", "id": "15242759", "url": "https://pubmed.ncbi.nlm.nih.gov/15242759" }, { "database": "PubMed", "id": "15246682", "url": "https://pubmed.ncbi.nlm.nih.gov/15246682" }, { "database": "PubMed", "id": "15263022", "url": "https://pubmed.ncbi.nlm.nih.gov/15263022" }, { "database": "PubMed", "id": "15331608", "url": "https://pubmed.ncbi.nlm.nih.gov/15331608" }, { "database": "PubMed", "id": "15598735", "url": "https://pubmed.ncbi.nlm.nih.gov/15598735" }, { "database": "PubMed", "id": "15611137", "url": "https://pubmed.ncbi.nlm.nih.gov/15611137" }, { "database": "PubMed", "id": "15625302", "url": "https://pubmed.ncbi.nlm.nih.gov/15625302" }, { "database": "PubMed", "id": "15694384", "url": "https://pubmed.ncbi.nlm.nih.gov/15694384" }, { "database": "PubMed", "id": "15707572", "url": "https://pubmed.ncbi.nlm.nih.gov/15707572" }, { "database": "PubMed", "id": "15707596", "url": "https://pubmed.ncbi.nlm.nih.gov/15707596" }, { "database": "PubMed", "id": "15785954", "url": "https://pubmed.ncbi.nlm.nih.gov/15785954" }, { "database": "PubMed", "id": "15817454", "url": "https://pubmed.ncbi.nlm.nih.gov/15817454" }, { "database": "PubMed", "id": "15890789", "url": "https://pubmed.ncbi.nlm.nih.gov/15890789" }, { "database": "PubMed", "id": "15963258", "url": "https://pubmed.ncbi.nlm.nih.gov/15963258" }, { "database": "PubMed", "id": "16039608", "url": "https://pubmed.ncbi.nlm.nih.gov/16039608" }, { "database": "PubMed", "id": "16153436", "url": "https://pubmed.ncbi.nlm.nih.gov/16153436" }, { "database": "PubMed", "id": "16159962", "url": "https://pubmed.ncbi.nlm.nih.gov/16159962" }, { "database": "PubMed", "id": "16195476", "url": "https://pubmed.ncbi.nlm.nih.gov/16195476" }, { "database": "PubMed", "id": "16253116", "url": "https://pubmed.ncbi.nlm.nih.gov/16253116" }, { "database": "PubMed", "id": "16267008", "url": "https://pubmed.ncbi.nlm.nih.gov/16267008" }, { "database": "PubMed", "id": "16275754", "url": "https://pubmed.ncbi.nlm.nih.gov/16275754" }, { "database": "PubMed", "id": "16415178", "url": "https://pubmed.ncbi.nlm.nih.gov/16415178" }, { "database": "PubMed", "id": "16461767", "url": "https://pubmed.ncbi.nlm.nih.gov/16461767" }, { "database": "PubMed", "id": "16473349", "url": "https://pubmed.ncbi.nlm.nih.gov/16473349" }, { "database": "PubMed", "id": "16523241", "url": "https://pubmed.ncbi.nlm.nih.gov/16523241" }, { "database": "PubMed", "id": "16574795", "url": "https://pubmed.ncbi.nlm.nih.gov/16574795" }, { "database": "PubMed", "id": "16728403", "url": "https://pubmed.ncbi.nlm.nih.gov/16728403" }, { "database": "PubMed", "id": "16847103", "url": "https://pubmed.ncbi.nlm.nih.gov/16847103" }, { "database": "PubMed", "id": "16912186", "url": "https://pubmed.ncbi.nlm.nih.gov/16912186" }, { "database": "PubMed", "id": "16917494", "url": "https://pubmed.ncbi.nlm.nih.gov/16917494" }, { "database": "PubMed", "id": "16920701", "url": "https://pubmed.ncbi.nlm.nih.gov/16920701" }, { "database": "PubMed", "id": "16998832", "url": "https://pubmed.ncbi.nlm.nih.gov/16998832" }, { "database": "PubMed", "id": "17081517", "url": "https://pubmed.ncbi.nlm.nih.gov/17081517" }, { "database": "PubMed", "id": "17088251", "url": "https://pubmed.ncbi.nlm.nih.gov/17088251" }, { "database": "PubMed", "id": "17096371", "url": "https://pubmed.ncbi.nlm.nih.gov/17096371" }, { "database": "PubMed", "id": "17117420", "url": "https://pubmed.ncbi.nlm.nih.gov/17117420" }, { "database": "PubMed", "id": "17215324", "url": "https://pubmed.ncbi.nlm.nih.gov/17215324" }, { "database": "PubMed", "id": "17219439", "url": "https://pubmed.ncbi.nlm.nih.gov/17219439" }, { "database": "PubMed", "id": "17234774", "url": "https://pubmed.ncbi.nlm.nih.gov/17234774" }, { "database": "PubMed", "id": "17234784", "url": "https://pubmed.ncbi.nlm.nih.gov/17234784" }, { "database": "PubMed", "id": "17240116", "url": "https://pubmed.ncbi.nlm.nih.gov/17240116" }, { "database": "PubMed", "id": "17395594", "url": "https://pubmed.ncbi.nlm.nih.gov/17395594" }, { "database": "PubMed", "id": "17431114", "url": "https://pubmed.ncbi.nlm.nih.gov/17431114" }, { "database": "PubMed", "id": "17497960", "url": "https://pubmed.ncbi.nlm.nih.gov/17497960" }, { "database": "PubMed", "id": "17524523", "url": "https://pubmed.ncbi.nlm.nih.gov/17524523" }, { "database": "PubMed", "id": "17721515", "url": "https://pubmed.ncbi.nlm.nih.gov/17721515" }, { "database": "PubMed", "id": "17898132", "url": "https://pubmed.ncbi.nlm.nih.gov/17898132" }, { "database": "PubMed", "id": "18006843", "url": "https://pubmed.ncbi.nlm.nih.gov/18006843" }, { "database": "PubMed", "id": "18032789", "url": "https://pubmed.ncbi.nlm.nih.gov/18032789" }, { "database": "PubMed", "id": "18171471", "url": "https://pubmed.ncbi.nlm.nih.gov/18171471" }, { "database": "PubMed", "id": "18198129", "url": "https://pubmed.ncbi.nlm.nih.gov/18198129" }, { "database": "PubMed", "id": "18314876", "url": "https://pubmed.ncbi.nlm.nih.gov/18314876" }, { "database": "PubMed", "id": "18343694", "url": "https://pubmed.ncbi.nlm.nih.gov/18343694" }, { "database": "PubMed", "id": "18349846", "url": "https://pubmed.ncbi.nlm.nih.gov/18349846" }, { "database": "PubMed", "id": "18382658", "url": "https://pubmed.ncbi.nlm.nih.gov/18382658" }, { "database": "PubMed", "id": "18562041", "url": "https://pubmed.ncbi.nlm.nih.gov/18562041" }, { "database": "PubMed", "id": "18676832", "url": "https://pubmed.ncbi.nlm.nih.gov/18676832" }, { "database": "PubMed", "id": "18757826", "url": "https://pubmed.ncbi.nlm.nih.gov/18757826" }, { "database": "PubMed", "id": "18774960", "url": "https://pubmed.ncbi.nlm.nih.gov/18774960" }, { "database": "PubMed", "id": "18805444", "url": "https://pubmed.ncbi.nlm.nih.gov/18805444" }, { "database": "PubMed", "id": "18922173", "url": "https://pubmed.ncbi.nlm.nih.gov/18922173" }, { "database": "PubMed", "id": "18923058", "url": "https://pubmed.ncbi.nlm.nih.gov/18923058" }, { "database": "PubMed", "id": "18930841", "url": "https://pubmed.ncbi.nlm.nih.gov/18930841" }, { "database": "PubMed", "id": "18989950", "url": "https://pubmed.ncbi.nlm.nih.gov/18989950" }, { "database": "PubMed", "id": "19029090", "url": "https://pubmed.ncbi.nlm.nih.gov/19029090" }, { "database": "PubMed", "id": "19190626", "url": "https://pubmed.ncbi.nlm.nih.gov/19190626" }, { "database": "PubMed", "id": "19212436", "url": "https://pubmed.ncbi.nlm.nih.gov/19212436" }, { "database": "PubMed", "id": "19260479", "url": "https://pubmed.ncbi.nlm.nih.gov/19260479" }, { "database": "PubMed", "id": "19294408", "url": "https://pubmed.ncbi.nlm.nih.gov/19294408" }, { "database": "PubMed", "id": "19297531", "url": "https://pubmed.ncbi.nlm.nih.gov/19297531" }, { "database": "PubMed", "id": "19553453", "url": "https://pubmed.ncbi.nlm.nih.gov/19553453" }, { "database": "PubMed", "id": "19568240", "url": "https://pubmed.ncbi.nlm.nih.gov/19568240" }, { "database": "PubMed", "id": "19657053", "url": "https://pubmed.ncbi.nlm.nih.gov/19657053" }, { "database": "PubMed", "id": "19671193", "url": "https://pubmed.ncbi.nlm.nih.gov/19671193" }, { "database": "PubMed", "id": "19695571", "url": "https://pubmed.ncbi.nlm.nih.gov/19695571" }, { "database": "PubMed", "id": "19740433", "url": "https://pubmed.ncbi.nlm.nih.gov/19740433" }, { "database": "PubMed", "id": "19787193", "url": "https://pubmed.ncbi.nlm.nih.gov/19787193" }, { "database": "PubMed", "id": "19826415", "url": "https://pubmed.ncbi.nlm.nih.gov/19826415" }, { "database": "PubMed", "id": "19834610", "url": "https://pubmed.ncbi.nlm.nih.gov/19834610" }, { "database": "PubMed", "id": "19883375", "url": "https://pubmed.ncbi.nlm.nih.gov/19883375" }, { "database": "PubMed", "id": "19923420", "url": "https://pubmed.ncbi.nlm.nih.gov/19923420" }, { "database": "PubMed", "id": "19931412", "url": "https://pubmed.ncbi.nlm.nih.gov/19931412" }, { "database": "PubMed", "id": "20014455", "url": "https://pubmed.ncbi.nlm.nih.gov/20014455" }, { "database": "PubMed", "id": "20018849", "url": "https://pubmed.ncbi.nlm.nih.gov/20018849" }, { "database": "PubMed", "id": "20021699", "url": "https://pubmed.ncbi.nlm.nih.gov/20021699" }, { "database": "PubMed", "id": "20082722", "url": "https://pubmed.ncbi.nlm.nih.gov/20082722" }, { "database": "PubMed", "id": "20122724", "url": "https://pubmed.ncbi.nlm.nih.gov/20122724" }, { "database": "PubMed", "id": "20160475", "url": "https://pubmed.ncbi.nlm.nih.gov/20160475" }, { "database": "PubMed", "id": "20180147", "url": "https://pubmed.ncbi.nlm.nih.gov/20180147" }, { "database": "PubMed", "id": "20224789", "url": "https://pubmed.ncbi.nlm.nih.gov/20224789" }, { "database": "PubMed", "id": "20308429", "url": "https://pubmed.ncbi.nlm.nih.gov/20308429" }, { "database": "PubMed", "id": "20354780", "url": "https://pubmed.ncbi.nlm.nih.gov/20354780" }, { "database": "PubMed", "id": "20357007", "url": "https://pubmed.ncbi.nlm.nih.gov/20357007" }, { "database": "PubMed", "id": "20378826", "url": "https://pubmed.ncbi.nlm.nih.gov/20378826" }, { "database": "PubMed", "id": "20527022", "url": "https://pubmed.ncbi.nlm.nih.gov/20527022" }, { "database": "PubMed", "id": "20621036", "url": "https://pubmed.ncbi.nlm.nih.gov/20621036" }, { "database": "PubMed", "id": "20657775", "url": "https://pubmed.ncbi.nlm.nih.gov/20657775" }, { "database": "PubMed", "id": "20713357", "url": "https://pubmed.ncbi.nlm.nih.gov/20713357" }, { "database": "PubMed", "id": "20724588", "url": "https://pubmed.ncbi.nlm.nih.gov/20724588" }, { "database": "PubMed", "id": "20802517", "url": "https://pubmed.ncbi.nlm.nih.gov/20802517" }, { "database": "PubMed", "id": "20847951", "url": "https://pubmed.ncbi.nlm.nih.gov/20847951" }, { "database": "PubMed", "id": "20927395", "url": "https://pubmed.ncbi.nlm.nih.gov/20927395" }, { "database": "PubMed", "id": "20955590", "url": "https://pubmed.ncbi.nlm.nih.gov/20955590" }, { "database": "PubMed", "id": "21073482", "url": "https://pubmed.ncbi.nlm.nih.gov/21073482" }, { "database": "PubMed", "id": "21084641", "url": "https://pubmed.ncbi.nlm.nih.gov/21084641" }, { "database": "PubMed", "id": "21119598", "url": "https://pubmed.ncbi.nlm.nih.gov/21119598" }, { "database": "PubMed", "id": "21209368", "url": "https://pubmed.ncbi.nlm.nih.gov/21209368" }, { "database": "PubMed", "id": "21344482", "url": "https://pubmed.ncbi.nlm.nih.gov/21344482" }, { "database": "PubMed", "id": "21359179", "url": "https://pubmed.ncbi.nlm.nih.gov/21359179" }, { "database": "PubMed", "id": "21401419", "url": "https://pubmed.ncbi.nlm.nih.gov/21401419" }, { "database": "PubMed", "id": "21408150", "url": "https://pubmed.ncbi.nlm.nih.gov/21408150" }, { "database": "PubMed", "id": "21418517", "url": "https://pubmed.ncbi.nlm.nih.gov/21418517" }, { "database": "PubMed", "id": "21426305", "url": "https://pubmed.ncbi.nlm.nih.gov/21426305" }, { "database": "PubMed", "id": "21556755", "url": "https://pubmed.ncbi.nlm.nih.gov/21556755" }, { "database": "PubMed", "id": "21660950", "url": "https://pubmed.ncbi.nlm.nih.gov/21660950" }, { "database": "PubMed", "id": "21716326", "url": "https://pubmed.ncbi.nlm.nih.gov/21716326" }, { "database": "PubMed", "id": "21720547", "url": "https://pubmed.ncbi.nlm.nih.gov/21720547" }, { "database": "PubMed", "id": "21887232", "url": "https://pubmed.ncbi.nlm.nih.gov/21887232" }, { "database": "PubMed", "id": "21898412", "url": "https://pubmed.ncbi.nlm.nih.gov/21898412" }, { "database": "PubMed", "id": "21903606", "url": "https://pubmed.ncbi.nlm.nih.gov/21903606" }, { "database": "PubMed", "id": "21967109", "url": "https://pubmed.ncbi.nlm.nih.gov/21967109" }, { "database": "PubMed", "id": "22042621", "url": "https://pubmed.ncbi.nlm.nih.gov/22042621" }, { "database": "PubMed", "id": "22069492", "url": "https://pubmed.ncbi.nlm.nih.gov/22069492" }, { "database": "PubMed", "id": "22070920", "url": "https://pubmed.ncbi.nlm.nih.gov/22070920" }, { "database": "PubMed", "id": "22078467", "url": "https://pubmed.ncbi.nlm.nih.gov/22078467" }, { "database": "PubMed", "id": "22136719", "url": "https://pubmed.ncbi.nlm.nih.gov/22136719" }, { "database": "PubMed", "id": "22149259", "url": "https://pubmed.ncbi.nlm.nih.gov/22149259" }, { "database": "PubMed", "id": "22174684", "url": "https://pubmed.ncbi.nlm.nih.gov/22174684" }, { "database": "PubMed", "id": "22194972", "url": "https://pubmed.ncbi.nlm.nih.gov/22194972" }, { "database": "PubMed", "id": "22216254", "url": "https://pubmed.ncbi.nlm.nih.gov/22216254" }, { "database": "PubMed", "id": "22267972", "url": "https://pubmed.ncbi.nlm.nih.gov/22267972" }, { "database": "PubMed", "id": "22270917", "url": "https://pubmed.ncbi.nlm.nih.gov/22270917" }, { "database": "PubMed", "id": "22319618", "url": "https://pubmed.ncbi.nlm.nih.gov/22319618" }, { "database": "PubMed", "id": "22544741", "url": "https://pubmed.ncbi.nlm.nih.gov/22544741" }, { "database": "PubMed", "id": "22550026", "url": "https://pubmed.ncbi.nlm.nih.gov/22550026" }, { "database": "PubMed", "id": "22641287", "url": "https://pubmed.ncbi.nlm.nih.gov/22641287" }, { "database": "PubMed", "id": "22710722", "url": "https://pubmed.ncbi.nlm.nih.gov/22710722" }, { "database": "PubMed", "id": "22734001", "url": "https://pubmed.ncbi.nlm.nih.gov/22734001" }, { "database": "PubMed", "id": "22766511", "url": "https://pubmed.ncbi.nlm.nih.gov/22766511" }, { "database": "PubMed", "id": "22810307", "url": "https://pubmed.ncbi.nlm.nih.gov/22810307" }, { "database": "PubMed", "id": "22824793", "url": "https://pubmed.ncbi.nlm.nih.gov/22824793" }, { "database": "PubMed", "id": "22876288", "url": "https://pubmed.ncbi.nlm.nih.gov/22876288" }, { "database": "PubMed", "id": "22938480", "url": "https://pubmed.ncbi.nlm.nih.gov/22938480" }, { "database": "PubMed", "id": "22952866", "url": "https://pubmed.ncbi.nlm.nih.gov/22952866" }, { "database": "PubMed", "id": "22982417", "url": "https://pubmed.ncbi.nlm.nih.gov/22982417" }, { "database": "PubMed", "id": "23102268", "url": "https://pubmed.ncbi.nlm.nih.gov/23102268" }, { "database": "PubMed", "id": "23109808", "url": "https://pubmed.ncbi.nlm.nih.gov/23109808" }, { "database": "PubMed", "id": "23128389", "url": "https://pubmed.ncbi.nlm.nih.gov/23128389" }, { "database": "PubMed", "id": "23209645", "url": "https://pubmed.ncbi.nlm.nih.gov/23209645" }, { "database": "PubMed", "id": "23264741", "url": "https://pubmed.ncbi.nlm.nih.gov/23264741" }, { "database": "PubMed", "id": "23272972", "url": "https://pubmed.ncbi.nlm.nih.gov/23272972" }, { "database": "PubMed", "id": "23339185", "url": "https://pubmed.ncbi.nlm.nih.gov/23339185" }, { "database": "PubMed", "id": "23357870", "url": "https://pubmed.ncbi.nlm.nih.gov/23357870" }, { "database": "PubMed", "id": "23485561", "url": "https://pubmed.ncbi.nlm.nih.gov/23485561" }, { "database": "PubMed", "id": "23515360", "url": "https://pubmed.ncbi.nlm.nih.gov/23515360" }, { "database": "PubMed", "id": "23525457", "url": "https://pubmed.ncbi.nlm.nih.gov/23525457" }, { "database": "PubMed", "id": "23681745", "url": "https://pubmed.ncbi.nlm.nih.gov/23681745" }, { "database": "PubMed", "id": "23755096", "url": "https://pubmed.ncbi.nlm.nih.gov/23755096" }, { "database": "PubMed", "id": "23755149", "url": "https://pubmed.ncbi.nlm.nih.gov/23755149" }, { "database": "PubMed", "id": "23792569", "url": "https://pubmed.ncbi.nlm.nih.gov/23792569" }, { "database": "PubMed", "id": "23812425", "url": "https://pubmed.ncbi.nlm.nih.gov/23812425" }, { "database": "PubMed", "id": "23836527", "url": "https://pubmed.ncbi.nlm.nih.gov/23836527" }, { "database": "PubMed", "id": "23858760", "url": "https://pubmed.ncbi.nlm.nih.gov/23858760" }, { "database": "PubMed", "id": "23874694", "url": "https://pubmed.ncbi.nlm.nih.gov/23874694" }, { "database": "PubMed", "id": "23970932", "url": "https://pubmed.ncbi.nlm.nih.gov/23970932" }, { "database": "PubMed", "id": "23984323", "url": "https://pubmed.ncbi.nlm.nih.gov/23984323" }, { "database": "PubMed", "id": "24010829", "url": "https://pubmed.ncbi.nlm.nih.gov/24010829" }, { "database": "PubMed", "id": "24025096", "url": "https://pubmed.ncbi.nlm.nih.gov/24025096" }, { "database": "PubMed", "id": "24039840", "url": "https://pubmed.ncbi.nlm.nih.gov/24039840" }, { "database": "PubMed", "id": "24039841", "url": "https://pubmed.ncbi.nlm.nih.gov/24039841" }, { "database": "PubMed", "id": "24040310", "url": "https://pubmed.ncbi.nlm.nih.gov/24040310" }, { "database": "PubMed", "id": "24058594", "url": "https://pubmed.ncbi.nlm.nih.gov/24058594" }, { "database": "PubMed", "id": "24062525", "url": "https://pubmed.ncbi.nlm.nih.gov/24062525" }, { "database": "PubMed", "id": "24083092", "url": "https://pubmed.ncbi.nlm.nih.gov/24083092" }, { "database": "PubMed", "id": "24091658", "url": "https://pubmed.ncbi.nlm.nih.gov/24091658" }, { "database": "PubMed", "id": "24121667", "url": "https://pubmed.ncbi.nlm.nih.gov/24121667" }, { "database": "PubMed", "id": "24123071", "url": "https://pubmed.ncbi.nlm.nih.gov/24123071" }, { "database": "PubMed", "id": "24194567", "url": "https://pubmed.ncbi.nlm.nih.gov/24194567" }, { "database": "PubMed", "id": "24201748", "url": "https://pubmed.ncbi.nlm.nih.gov/24201748" }, { "database": "PubMed", "id": "24260201", "url": "https://pubmed.ncbi.nlm.nih.gov/24260201" }, { "database": "PubMed", "id": "24290759", "url": "https://pubmed.ncbi.nlm.nih.gov/24290759" }, { "database": "PubMed", "id": "24294595", "url": "https://pubmed.ncbi.nlm.nih.gov/24294595" }, { "database": "PubMed", "id": "24360952", "url": "https://pubmed.ncbi.nlm.nih.gov/24360952" }, { "database": "PubMed", "id": "24370784", "url": "https://pubmed.ncbi.nlm.nih.gov/24370784" }, { "database": "PubMed", "id": "24381802", "url": "https://pubmed.ncbi.nlm.nih.gov/24381802" }, { "database": "PubMed", "id": "24409152", "url": "https://pubmed.ncbi.nlm.nih.gov/24409152" }, { "database": "PubMed", "id": "24533083", "url": "https://pubmed.ncbi.nlm.nih.gov/24533083" }, { "database": "PubMed", "id": "24586773", "url": "https://pubmed.ncbi.nlm.nih.gov/24586773" }, { "database": "PubMed", "id": "24632806", "url": "https://pubmed.ncbi.nlm.nih.gov/24632806" }, { "database": "PubMed", "id": "24642576", "url": "https://pubmed.ncbi.nlm.nih.gov/24642576" }, { "database": "PubMed", "id": "24655477", "url": "https://pubmed.ncbi.nlm.nih.gov/24655477" }, { "database": "PubMed", "id": "24681892", "url": "https://pubmed.ncbi.nlm.nih.gov/24681892" }, { "database": "PubMed", "id": "24706070", "url": "https://pubmed.ncbi.nlm.nih.gov/24706070" }, { "database": "PubMed", "id": "24736807", "url": "https://pubmed.ncbi.nlm.nih.gov/24736807" }, { "database": "PubMed", "id": "24772088", "url": "https://pubmed.ncbi.nlm.nih.gov/24772088" }, { "database": "PubMed", "id": "24786638", "url": "https://pubmed.ncbi.nlm.nih.gov/24786638" }, { "database": "PubMed", "id": "24858039", "url": "https://pubmed.ncbi.nlm.nih.gov/24858039" }, { "database": "PubMed", "id": "24863845", "url": "https://pubmed.ncbi.nlm.nih.gov/24863845" }, { "database": "PubMed", "id": "24885534", "url": "https://pubmed.ncbi.nlm.nih.gov/24885534" }, { "database": "PubMed", "id": "24885567", "url": "https://pubmed.ncbi.nlm.nih.gov/24885567" }, { "database": "PubMed", "id": "24894151", "url": "https://pubmed.ncbi.nlm.nih.gov/24894151" }, { "database": "PubMed", "id": "24911159", "url": "https://pubmed.ncbi.nlm.nih.gov/24911159" }, { "database": "PubMed", "id": "24999733", "url": "https://pubmed.ncbi.nlm.nih.gov/24999733" }, { "database": "PubMed", "id": "25056351", "url": "https://pubmed.ncbi.nlm.nih.gov/25056351" }, { "database": "PubMed", "id": "25113248", "url": "https://pubmed.ncbi.nlm.nih.gov/25113248" }, { "database": "PubMed", "id": "25187949", "url": "https://pubmed.ncbi.nlm.nih.gov/25187949" }, { "database": "PubMed", "id": "25193862", "url": "https://pubmed.ncbi.nlm.nih.gov/25193862" }, { "database": "PubMed", "id": "25226367", "url": "https://pubmed.ncbi.nlm.nih.gov/25226367" }, { "database": "PubMed", "id": "25277206", "url": "https://pubmed.ncbi.nlm.nih.gov/25277206" }, { "database": "PubMed", "id": "25300309", "url": "https://pubmed.ncbi.nlm.nih.gov/25300309" }, { "database": "PubMed", "id": "25313365", "url": "https://pubmed.ncbi.nlm.nih.gov/25313365" }, { "database": "PubMed", "id": "25351103", "url": "https://pubmed.ncbi.nlm.nih.gov/25351103" }, { "database": "PubMed", "id": "25428919", "url": "https://pubmed.ncbi.nlm.nih.gov/25428919" }, { "database": "PubMed", "id": "25486573", "url": "https://pubmed.ncbi.nlm.nih.gov/25486573" }, { "database": "PubMed", "id": "25539072", "url": "https://pubmed.ncbi.nlm.nih.gov/25539072" }, { "database": "PubMed", "id": "25611393", "url": "https://pubmed.ncbi.nlm.nih.gov/25611393" }, { "database": "PubMed", "id": "25617898", "url": "https://pubmed.ncbi.nlm.nih.gov/25617898" }, { "database": "PubMed", "id": "25631868", "url": "https://pubmed.ncbi.nlm.nih.gov/25631868" }, { "database": "PubMed", "id": "25705585", "url": "https://pubmed.ncbi.nlm.nih.gov/25705585" }, { "database": "PubMed", "id": "25708150", "url": "https://pubmed.ncbi.nlm.nih.gov/25708150" }, { "database": "PubMed", "id": "25749031", "url": "https://pubmed.ncbi.nlm.nih.gov/25749031" }, { "database": "PubMed", "id": "25753414", "url": "https://pubmed.ncbi.nlm.nih.gov/25753414" }, { "database": "PubMed", "id": "25778692", "url": "https://pubmed.ncbi.nlm.nih.gov/25778692" }, { "database": "PubMed", "id": "25868388", "url": "https://pubmed.ncbi.nlm.nih.gov/25868388" }, { "database": "PubMed", "id": "25880415", "url": "https://pubmed.ncbi.nlm.nih.gov/25880415" }, { "database": "PubMed", "id": "25889845", "url": "https://pubmed.ncbi.nlm.nih.gov/25889845" }, { "database": "PubMed", "id": "25890707", "url": "https://pubmed.ncbi.nlm.nih.gov/25890707" }, { "database": "PubMed", "id": "25947155", "url": "https://pubmed.ncbi.nlm.nih.gov/25947155" }, { "database": "PubMed", "id": "25949790", "url": "https://pubmed.ncbi.nlm.nih.gov/25949790" }, { "database": "PubMed", "id": "25958313", "url": "https://pubmed.ncbi.nlm.nih.gov/25958313" }, { "database": "PubMed", "id": "25978354", "url": "https://pubmed.ncbi.nlm.nih.gov/25978354" }, { "database": "PubMed", "id": "25980494", "url": "https://pubmed.ncbi.nlm.nih.gov/25980494" }, { "database": "PubMed", "id": "26004127", "url": "https://pubmed.ncbi.nlm.nih.gov/26004127" }, { "database": "PubMed", "id": "26079101", "url": "https://pubmed.ncbi.nlm.nih.gov/26079101" }, { "database": "PubMed", "id": "26110647", "url": "https://pubmed.ncbi.nlm.nih.gov/26110647" }, { "database": "PubMed", "id": "26119934", "url": "https://pubmed.ncbi.nlm.nih.gov/26119934" }, { "database": "PubMed", "id": "26172215", "url": "https://pubmed.ncbi.nlm.nih.gov/26172215" }, { "database": "PubMed", "id": "26216901", "url": "https://pubmed.ncbi.nlm.nih.gov/26216901" }, { "database": "PubMed", "id": "26230358", "url": "https://pubmed.ncbi.nlm.nih.gov/26230358" }, { "database": "PubMed", "id": "26245992", "url": "https://pubmed.ncbi.nlm.nih.gov/26245992" }, { "database": "PubMed", "id": "26294392", "url": "https://pubmed.ncbi.nlm.nih.gov/26294392" }, { "database": "PubMed", "id": "26300973", "url": "https://pubmed.ncbi.nlm.nih.gov/26300973" }, { "database": "PubMed", "id": "26365310", "url": "https://pubmed.ncbi.nlm.nih.gov/26365310" }, { "database": "PubMed", "id": "26375443", "url": "https://pubmed.ncbi.nlm.nih.gov/26375443" }, { "database": "PubMed", "id": "26377974", "url": "https://pubmed.ncbi.nlm.nih.gov/26377974" }, { "database": "PubMed", "id": "26393679", "url": "https://pubmed.ncbi.nlm.nih.gov/26393679" }, { "database": "PubMed", "id": "26406376", "url": "https://pubmed.ncbi.nlm.nih.gov/26406376" }, { "database": "PubMed", "id": "26456697", "url": "https://pubmed.ncbi.nlm.nih.gov/26456697" }, { "database": "PubMed", "id": "26501082", "url": "https://pubmed.ncbi.nlm.nih.gov/26501082" }, { "database": "PubMed", "id": "26542021", "url": "https://pubmed.ncbi.nlm.nih.gov/26542021" }, { "database": "PubMed", "id": "26546726", "url": "https://pubmed.ncbi.nlm.nih.gov/26546726" }, { "database": "PubMed", "id": "26549523", "url": "https://pubmed.ncbi.nlm.nih.gov/26549523" }, { "database": "PubMed", "id": "26556867", "url": "https://pubmed.ncbi.nlm.nih.gov/26556867" }, { "database": "PubMed", "id": "26649283", "url": "https://pubmed.ncbi.nlm.nih.gov/26649283" }, { "database": "PubMed", "id": "26689988", "url": "https://pubmed.ncbi.nlm.nih.gov/26689988" }, { "database": "PubMed", "id": "26700725", "url": "https://pubmed.ncbi.nlm.nih.gov/26700725" }, { "database": "PubMed", "id": "26703626", "url": "https://pubmed.ncbi.nlm.nih.gov/26703626" }, { "database": "PubMed", "id": "26751774", "url": "https://pubmed.ncbi.nlm.nih.gov/26751774" }, { "database": "PubMed", "id": "26752742", "url": "https://pubmed.ncbi.nlm.nih.gov/26752742" }, { "database": "PubMed", "id": "26788094", "url": "https://pubmed.ncbi.nlm.nih.gov/26788094" }, { "database": "PubMed", "id": "26821125", "url": "https://pubmed.ncbi.nlm.nih.gov/26821125" }, { "database": "PubMed", "id": "26833789", "url": "https://pubmed.ncbi.nlm.nih.gov/26833789" }, { "database": "PubMed", "id": "26842895", "url": "https://pubmed.ncbi.nlm.nih.gov/26842895" }, { "database": "PubMed", "id": "26848618", "url": "https://pubmed.ncbi.nlm.nih.gov/26848618" }, { "database": "PubMed", "id": "26866924", "url": "https://pubmed.ncbi.nlm.nih.gov/26866924" }, { "database": "PubMed", "id": "26893679", "url": "https://pubmed.ncbi.nlm.nih.gov/26893679" }, { "database": "PubMed", "id": "26931461", "url": "https://pubmed.ncbi.nlm.nih.gov/26931461" }, { "database": "PubMed", "id": "26961176", "url": "https://pubmed.ncbi.nlm.nih.gov/26961176" }, { "database": "PubMed", "id": "26975850", "url": "https://pubmed.ncbi.nlm.nih.gov/26975850" }, { "database": "PubMed", "id": "26984508", "url": "https://pubmed.ncbi.nlm.nih.gov/26984508" }, { "database": "PubMed", "id": "26984511", "url": "https://pubmed.ncbi.nlm.nih.gov/26984511" }, { "database": "PubMed", "id": "26988603", "url": "https://pubmed.ncbi.nlm.nih.gov/26988603" }, { "database": "PubMed", "id": "26993780", "url": "https://pubmed.ncbi.nlm.nih.gov/26993780" }, { "database": "PubMed", "id": "27041993", "url": "https://pubmed.ncbi.nlm.nih.gov/27041993" }, { "database": "PubMed", "id": "27145276", "url": "https://pubmed.ncbi.nlm.nih.gov/27145276" }, { "database": "PubMed", "id": "27191259", "url": "https://pubmed.ncbi.nlm.nih.gov/27191259" }, { "database": "PubMed", "id": "27220365", "url": "https://pubmed.ncbi.nlm.nih.gov/27220365" }, { "database": "PubMed", "id": "27237320", "url": "https://pubmed.ncbi.nlm.nih.gov/27237320" }, { "database": "PubMed", "id": "27246739", "url": "https://pubmed.ncbi.nlm.nih.gov/27246739" }, { "database": "PubMed", "id": "27248472", "url": "https://pubmed.ncbi.nlm.nih.gov/27248472" }, { "database": "PubMed", "id": "27278471", "url": "https://pubmed.ncbi.nlm.nih.gov/27278471" }, { "database": "PubMed", "id": "27286256", "url": "https://pubmed.ncbi.nlm.nih.gov/27286256" }, { "database": "PubMed", "id": "27344177", "url": "https://pubmed.ncbi.nlm.nih.gov/27344177" }, { "database": "PubMed", "id": "27363027", "url": "https://pubmed.ncbi.nlm.nih.gov/27363027" }, { "database": "PubMed", "id": "27402964", "url": "https://pubmed.ncbi.nlm.nih.gov/27402964" }, { "database": "PubMed", "id": "27428469", "url": "https://pubmed.ncbi.nlm.nih.gov/27428469" }, { "database": "PubMed", "id": "27460083", "url": "https://pubmed.ncbi.nlm.nih.gov/27460083" }, { "database": "PubMed", "id": "27462783", "url": "https://pubmed.ncbi.nlm.nih.gov/27462783" }, { "database": "PubMed", "id": "27467982", "url": "https://pubmed.ncbi.nlm.nih.gov/27467982" }, { "database": "PubMed", "id": "27487141", "url": "https://pubmed.ncbi.nlm.nih.gov/27487141" }, { "database": "PubMed", "id": "27542844", "url": "https://pubmed.ncbi.nlm.nih.gov/27542844" }, { "database": "PubMed", "id": "27567948", "url": "https://pubmed.ncbi.nlm.nih.gov/27567948" }, { "database": "PubMed", "id": "27602495", "url": "https://pubmed.ncbi.nlm.nih.gov/27602495" }, { "database": "PubMed", "id": "27611942", "url": "https://pubmed.ncbi.nlm.nih.gov/27611942" }, { "database": "PubMed", "id": "27638858", "url": "https://pubmed.ncbi.nlm.nih.gov/27638858" }, { "database": "PubMed", "id": "27715394", "url": "https://pubmed.ncbi.nlm.nih.gov/27715394" }, { "database": "PubMed", "id": "27845385", "url": "https://pubmed.ncbi.nlm.nih.gov/27845385" }, { "database": "PubMed", "id": "28053698", "url": "https://pubmed.ncbi.nlm.nih.gov/28053698" }, { "database": "PubMed", "id": "28068967", "url": "https://pubmed.ncbi.nlm.nih.gov/28068967" }, { "database": "PubMed", "id": "28076322", "url": "https://pubmed.ncbi.nlm.nih.gov/28076322" }, { "database": "PubMed", "id": "28124908", "url": "https://pubmed.ncbi.nlm.nih.gov/28124908" }, { "database": "PubMed", "id": "28134933", "url": "https://pubmed.ncbi.nlm.nih.gov/28134933" }, { "database": "PubMed", "id": "28188308", "url": "https://pubmed.ncbi.nlm.nih.gov/28188308" }, { "database": "PubMed", "id": "28222177", "url": "https://pubmed.ncbi.nlm.nih.gov/28222177" }, { "database": "PubMed", "id": "28225063", "url": "https://pubmed.ncbi.nlm.nih.gov/28225063" }, { "database": "PubMed", "id": "28257035", "url": "https://pubmed.ncbi.nlm.nih.gov/28257035" }, { "database": "PubMed", "id": "28338656", "url": "https://pubmed.ncbi.nlm.nih.gov/28338656" }, { "database": "PubMed", "id": "28361970", "url": "https://pubmed.ncbi.nlm.nih.gov/28361970" }, { "database": "PubMed", "id": "28398603", "url": "https://pubmed.ncbi.nlm.nih.gov/28398603" }, { "database": "PubMed", "id": "28406574", "url": "https://pubmed.ncbi.nlm.nih.gov/28406574" }, { "database": "PubMed", "id": "28415713", "url": "https://pubmed.ncbi.nlm.nih.gov/28415713" }, { "database": "PubMed", "id": "28418903", "url": "https://pubmed.ncbi.nlm.nih.gov/28418903" }, { "database": "PubMed", "id": "28423580", "url": "https://pubmed.ncbi.nlm.nih.gov/28423580" }, { "database": "PubMed", "id": "28427224", "url": "https://pubmed.ncbi.nlm.nih.gov/28427224" }, { "database": "PubMed", "id": "28445805", "url": "https://pubmed.ncbi.nlm.nih.gov/28445805" }, { "database": "PubMed", "id": "28450296", "url": "https://pubmed.ncbi.nlm.nih.gov/28450296" }, { "database": "PubMed", "id": "28459432", "url": "https://pubmed.ncbi.nlm.nih.gov/28459432" }, { "database": "PubMed", "id": "28507287", "url": "https://pubmed.ncbi.nlm.nih.gov/28507287" }, { "database": "PubMed", "id": "28542214", "url": "https://pubmed.ncbi.nlm.nih.gov/28542214" }, { "database": "PubMed", "id": "28624785", "url": "https://pubmed.ncbi.nlm.nih.gov/28624785" }, { "database": "PubMed", "id": "28642549", "url": "https://pubmed.ncbi.nlm.nih.gov/28642549" }, { "database": "PubMed", "id": "28667800", "url": "https://pubmed.ncbi.nlm.nih.gov/28667800" }, { "database": "PubMed", "id": "28715434", "url": "https://pubmed.ncbi.nlm.nih.gov/28715434" }, { "database": "PubMed", "id": "28741790", "url": "https://pubmed.ncbi.nlm.nih.gov/28741790" }, { "database": "PubMed", "id": "29021002", "url": "https://pubmed.ncbi.nlm.nih.gov/29021002" }, { "database": "PubMed", "id": "29036202", "url": "https://pubmed.ncbi.nlm.nih.gov/29036202" }, { "database": "PubMed", "id": "29039492", "url": "https://pubmed.ncbi.nlm.nih.gov/29039492" }, { "database": "PubMed", "id": "29046395", "url": "https://pubmed.ncbi.nlm.nih.gov/29046395" }, { "database": "PubMed", "id": "29050315", "url": "https://pubmed.ncbi.nlm.nih.gov/29050315" }, { "database": "PubMed", "id": "29066806", "url": "https://pubmed.ncbi.nlm.nih.gov/29066806" }, { "database": "PubMed", "id": "29088849", "url": "https://pubmed.ncbi.nlm.nih.gov/29088849" }, { "database": "PubMed", "id": "29151962", "url": "https://pubmed.ncbi.nlm.nih.gov/29151962" }, { "database": "PubMed", "id": "29158989", "url": "https://pubmed.ncbi.nlm.nih.gov/29158989" }, { "database": "PubMed", "id": "29186907", "url": "https://pubmed.ncbi.nlm.nih.gov/29186907" }, { "database": "PubMed", "id": "29190494", "url": "https://pubmed.ncbi.nlm.nih.gov/29190494" }, { "database": "PubMed", "id": "29228673", "url": "https://pubmed.ncbi.nlm.nih.gov/29228673" }, { "database": "PubMed", "id": "29263678", "url": "https://pubmed.ncbi.nlm.nih.gov/29263678" }, { "database": "PubMed", "id": "29276408", "url": "https://pubmed.ncbi.nlm.nih.gov/29276408" }, { "database": "PubMed", "id": "29311227", "url": "https://pubmed.ncbi.nlm.nih.gov/29311227" }, { "database": "PubMed", "id": "29382358", "url": "https://pubmed.ncbi.nlm.nih.gov/29382358" }, { "database": "PubMed", "id": "29422613", "url": "https://pubmed.ncbi.nlm.nih.gov/29422613" }, { "database": "PubMed", "id": "29434841", "url": "https://pubmed.ncbi.nlm.nih.gov/29434841" }, { "database": "PubMed", "id": "29439667", "url": "https://pubmed.ncbi.nlm.nih.gov/29439667" }, { "database": "PubMed", "id": "29484384", "url": "https://pubmed.ncbi.nlm.nih.gov/29484384" }, { "database": "PubMed", "id": "29491429", "url": "https://pubmed.ncbi.nlm.nih.gov/29491429" }, { "database": "PubMed", "id": "29535802", "url": "https://pubmed.ncbi.nlm.nih.gov/29535802" }, { "database": "PubMed", "id": "29563383", "url": "https://pubmed.ncbi.nlm.nih.gov/29563383" }, { "database": "PubMed", "id": "29593542", "url": "https://pubmed.ncbi.nlm.nih.gov/29593542" }, { "database": "PubMed", "id": "29700289", "url": "https://pubmed.ncbi.nlm.nih.gov/29700289" }, { "database": "PubMed", "id": "29728077", "url": "https://pubmed.ncbi.nlm.nih.gov/29728077" }, { "database": "PubMed", "id": "29740072", "url": "https://pubmed.ncbi.nlm.nih.gov/29740072" }, { "database": "PubMed", "id": "29752441", "url": "https://pubmed.ncbi.nlm.nih.gov/29752441" }, { "database": "PubMed", "id": "29791208", "url": "https://pubmed.ncbi.nlm.nih.gov/29791208" }, { "database": "PubMed", "id": "29796177", "url": "https://pubmed.ncbi.nlm.nih.gov/29796177" }, { "database": "PubMed", "id": "29903032", "url": "https://pubmed.ncbi.nlm.nih.gov/29903032" }, { "database": "PubMed", "id": "29915029", "url": "https://pubmed.ncbi.nlm.nih.gov/29915029" }, { "database": "PubMed", "id": "29928374", "url": "https://pubmed.ncbi.nlm.nih.gov/29928374" }, { "database": "PubMed", "id": "29986550", "url": "https://pubmed.ncbi.nlm.nih.gov/29986550" }, { "database": "PubMed", "id": "29993014", "url": "https://pubmed.ncbi.nlm.nih.gov/29993014" }, { "database": "PubMed", "id": "30013514", "url": "https://pubmed.ncbi.nlm.nih.gov/30013514" }, { "database": "PubMed", "id": "30033448", "url": "https://pubmed.ncbi.nlm.nih.gov/30033448" }, { "database": "PubMed", "id": "30055645", "url": "https://pubmed.ncbi.nlm.nih.gov/30055645" }, { "database": "PubMed", "id": "30065198", "url": "https://pubmed.ncbi.nlm.nih.gov/30065198" }, { "database": "PubMed", "id": "30087707", "url": "https://pubmed.ncbi.nlm.nih.gov/30087707" }, { "database": "PubMed", "id": "30166526", "url": "https://pubmed.ncbi.nlm.nih.gov/30166526" }, { "database": "PubMed", "id": "30332774", "url": "https://pubmed.ncbi.nlm.nih.gov/30332774" }, { "database": "PubMed", "id": "30337877", "url": "https://pubmed.ncbi.nlm.nih.gov/30337877" }, { "database": "PubMed", "id": "30347788", "url": "https://pubmed.ncbi.nlm.nih.gov/30347788" }, { "database": "PubMed", "id": "30387148", "url": "https://pubmed.ncbi.nlm.nih.gov/30387148" }, { "database": "PubMed", "id": "30458784", "url": "https://pubmed.ncbi.nlm.nih.gov/30458784" }, { "database": "PubMed", "id": "30464516", "url": "https://pubmed.ncbi.nlm.nih.gov/30464516" }, { "database": "PubMed", "id": "30488595", "url": "https://pubmed.ncbi.nlm.nih.gov/30488595" }, { "database": "PubMed", "id": "30498362", "url": "https://pubmed.ncbi.nlm.nih.gov/30498362" }, { "database": "PubMed", "id": "30531837", "url": "https://pubmed.ncbi.nlm.nih.gov/30531837" }, { "database": "PubMed", "id": "30539198", "url": "https://pubmed.ncbi.nlm.nih.gov/30539198" }, { "database": "PubMed", "id": "30555628", "url": "https://pubmed.ncbi.nlm.nih.gov/30555628" }, { "database": "PubMed", "id": "30563275", "url": "https://pubmed.ncbi.nlm.nih.gov/30563275" }, { "database": "PubMed", "id": "30571746", "url": "https://pubmed.ncbi.nlm.nih.gov/30571746" }, { "database": "PubMed", "id": "30696915", "url": "https://pubmed.ncbi.nlm.nih.gov/30696915" }, { "database": "PubMed", "id": "30717801", "url": "https://pubmed.ncbi.nlm.nih.gov/30717801" }, { "database": "PubMed", "id": "30728047", "url": "https://pubmed.ncbi.nlm.nih.gov/30728047" }, { "database": "PubMed", "id": "30742951", "url": "https://pubmed.ncbi.nlm.nih.gov/30742951" }, { "database": "PubMed", "id": "30744493", "url": "https://pubmed.ncbi.nlm.nih.gov/30744493" }, { "database": "PubMed", "id": "30761269", "url": "https://pubmed.ncbi.nlm.nih.gov/30761269" }, { "database": "PubMed", "id": "30779783", "url": "https://pubmed.ncbi.nlm.nih.gov/30779783" }, { "database": "PubMed", "id": "30816469", "url": "https://pubmed.ncbi.nlm.nih.gov/30816469" }, { "database": "PubMed", "id": "30836148", "url": "https://pubmed.ncbi.nlm.nih.gov/30836148" }, { "database": "PubMed", "id": "30894654", "url": "https://pubmed.ncbi.nlm.nih.gov/30894654" }, { "database": "PubMed", "id": "30920523", "url": "https://pubmed.ncbi.nlm.nih.gov/30920523" }, { "database": "PubMed", "id": "31006845", "url": "https://pubmed.ncbi.nlm.nih.gov/31006845" }, { "database": "PubMed", "id": "31060904", "url": "https://pubmed.ncbi.nlm.nih.gov/31060904" }, { "database": "PubMed", "id": "31160603", "url": "https://pubmed.ncbi.nlm.nih.gov/31160603" }, { "database": "PubMed", "id": "31170089", "url": "https://pubmed.ncbi.nlm.nih.gov/31170089" }, { "database": "PubMed", "id": "31186741", "url": "https://pubmed.ncbi.nlm.nih.gov/31186741" }, { "database": "PubMed", "id": "31297342", "url": "https://pubmed.ncbi.nlm.nih.gov/31297342" }, { "database": "PubMed", "id": "31383893", "url": "https://pubmed.ncbi.nlm.nih.gov/31383893" }, { "database": "PubMed", "id": "31420553", "url": "https://pubmed.ncbi.nlm.nih.gov/31420553" }, { "database": "PubMed", "id": "31428520", "url": "https://pubmed.ncbi.nlm.nih.gov/31428520" }, { "database": "PubMed", "id": "31478830", "url": "https://pubmed.ncbi.nlm.nih.gov/31478830" }, { "database": "PubMed", "id": "31480645", "url": "https://pubmed.ncbi.nlm.nih.gov/31480645" }, { "database": "PubMed", "id": "31501460", "url": "https://pubmed.ncbi.nlm.nih.gov/31501460" }, { "database": "PubMed", "id": "31516757", "url": "https://pubmed.ncbi.nlm.nih.gov/31516757" }, { "database": "PubMed", "id": "31519958", "url": "https://pubmed.ncbi.nlm.nih.gov/31519958" }, { "database": "PubMed", "id": "31554180", "url": "https://pubmed.ncbi.nlm.nih.gov/31554180" }, { "database": "PubMed", "id": "31565187", "url": "https://pubmed.ncbi.nlm.nih.gov/31565187" }, { "database": "PubMed", "id": "31627430", "url": "https://pubmed.ncbi.nlm.nih.gov/31627430" }, { "database": "PubMed", "id": "31648990", "url": "https://pubmed.ncbi.nlm.nih.gov/31648990" }, { "database": "PubMed", "id": "31652779", "url": "https://pubmed.ncbi.nlm.nih.gov/31652779" }, { "database": "PubMed", "id": "31654241", "url": "https://pubmed.ncbi.nlm.nih.gov/31654241" }, { "database": "PubMed", "id": "31671408", "url": "https://pubmed.ncbi.nlm.nih.gov/31671408" }, { "database": "PubMed", "id": "31671889", "url": "https://pubmed.ncbi.nlm.nih.gov/31671889" }, { "database": "PubMed", "id": "31831830", "url": "https://pubmed.ncbi.nlm.nih.gov/31831830" }, { "database": "PubMed", "id": "31867162", "url": "https://pubmed.ncbi.nlm.nih.gov/31867162" }, { "database": "PubMed", "id": "31870092", "url": "https://pubmed.ncbi.nlm.nih.gov/31870092" }, { "database": "PubMed", "id": "31926619", "url": "https://pubmed.ncbi.nlm.nih.gov/31926619" }, { "database": "PubMed", "id": "32155953", "url": "https://pubmed.ncbi.nlm.nih.gov/32155953" }, { "database": "PubMed", "id": "32256987", "url": "https://pubmed.ncbi.nlm.nih.gov/32256987" }, { "database": "PubMed", "id": "32274611", "url": "https://pubmed.ncbi.nlm.nih.gov/32274611" }, { "database": "PubMed", "id": "32286266", "url": "https://pubmed.ncbi.nlm.nih.gov/32286266" }, { "database": "PubMed", "id": "32337793", "url": "https://pubmed.ncbi.nlm.nih.gov/32337793" }, { "database": "PubMed", "id": "32415208", "url": "https://pubmed.ncbi.nlm.nih.gov/32415208" }, { "database": "PubMed", "id": "32604782", "url": "https://pubmed.ncbi.nlm.nih.gov/32604782" }, { "database": "PubMed", "id": "32733919", "url": "https://pubmed.ncbi.nlm.nih.gov/32733919" }, { "database": "PubMed", "id": "32784087", "url": "https://pubmed.ncbi.nlm.nih.gov/32784087" }, { "database": "PubMed", "id": "32806748", "url": "https://pubmed.ncbi.nlm.nih.gov/32806748" }, { "database": "PubMed", "id": "32843133", "url": "https://pubmed.ncbi.nlm.nih.gov/32843133" }, { "database": "PubMed", "id": "32844749", "url": "https://pubmed.ncbi.nlm.nih.gov/32844749" }, { "database": "PubMed", "id": "32848136", "url": "https://pubmed.ncbi.nlm.nih.gov/32848136" }, { "database": "PubMed", "id": "32850845", "url": "https://pubmed.ncbi.nlm.nih.gov/32850845" }, { "database": "PubMed", "id": "32872257", "url": "https://pubmed.ncbi.nlm.nih.gov/32872257" }, { "database": "PubMed", "id": "33025708", "url": "https://pubmed.ncbi.nlm.nih.gov/33025708" }, { "database": "PubMed", "id": "33036231", "url": "https://pubmed.ncbi.nlm.nih.gov/33036231" }, { "database": "PubMed", "id": "33076263", "url": "https://pubmed.ncbi.nlm.nih.gov/33076263" }, { "database": "PubMed", "id": "33184263", "url": "https://pubmed.ncbi.nlm.nih.gov/33184263" }, { "database": "PubMed", "id": "33287873", "url": "https://pubmed.ncbi.nlm.nih.gov/33287873" }, { "database": "PubMed", "id": "33413438", "url": "https://pubmed.ncbi.nlm.nih.gov/33413438" }, { "database": "PubMed", "id": "33420364", "url": "https://pubmed.ncbi.nlm.nih.gov/33420364" }, { "database": "PubMed", "id": "33532186", "url": "https://pubmed.ncbi.nlm.nih.gov/33532186" }, { "database": "PubMed", "id": "33614634", "url": "https://pubmed.ncbi.nlm.nih.gov/33614634" }, { "database": "PubMed", "id": "33634070", "url": "https://pubmed.ncbi.nlm.nih.gov/33634070" }, { "database": "PubMed", "id": "33668531", "url": "https://pubmed.ncbi.nlm.nih.gov/33668531" }, { "database": "PubMed", "id": "33715263", "url": "https://pubmed.ncbi.nlm.nih.gov/33715263" }, { "database": "PubMed", "id": "33724150", "url": "https://pubmed.ncbi.nlm.nih.gov/33724150" }, { "database": "PubMed", "id": "33750427", "url": "https://pubmed.ncbi.nlm.nih.gov/33750427" }, { "database": "PubMed", "id": "33799345", "url": "https://pubmed.ncbi.nlm.nih.gov/33799345" }, { "database": "PubMed", "id": "33846818", "url": "https://pubmed.ncbi.nlm.nih.gov/33846818" }, { "database": "PubMed", "id": "33898431", "url": "https://pubmed.ncbi.nlm.nih.gov/33898431" }, { "database": "PubMed", "id": "33920284", "url": "https://pubmed.ncbi.nlm.nih.gov/33920284" }, { "database": "PubMed", "id": "33981002", "url": "https://pubmed.ncbi.nlm.nih.gov/33981002" }, { "database": "PubMed", "id": "35201437", "url": "https://pubmed.ncbi.nlm.nih.gov/35201437" }, { "database": "PubMed", "id": "35257717", "url": "https://pubmed.ncbi.nlm.nih.gov/35257717" }, { "database": "PubMed", "id": "35426066", "url": "https://pubmed.ncbi.nlm.nih.gov/35426066" }, { "database": "PubMed", "id": "35962191", "url": "https://pubmed.ncbi.nlm.nih.gov/35962191" }, { "database": "PubMed", "id": "35982848", "url": "https://pubmed.ncbi.nlm.nih.gov/35982848" }, { "database": "PubMed", "id": "36009384", "url": "https://pubmed.ncbi.nlm.nih.gov/36009384" }, { "database": "PubMed", "id": "7553664", "url": "https://pubmed.ncbi.nlm.nih.gov/7553664" }, { "database": "PubMed", "id": "7739563", "url": "https://pubmed.ncbi.nlm.nih.gov/7739563" }, { "database": "PubMed", "id": "8051157", "url": "https://pubmed.ncbi.nlm.nih.gov/8051157" }, { "database": "PubMed", "id": "8824286", "url": "https://pubmed.ncbi.nlm.nih.gov/8824286" }, { "database": "PubMed", "id": "8941336", "url": "https://pubmed.ncbi.nlm.nih.gov/8941336" }, { "database": "PubMed", "id": "9148935", "url": "https://pubmed.ncbi.nlm.nih.gov/9148935" }, { "database": "PubMed", "id": "9416004", "url": "https://pubmed.ncbi.nlm.nih.gov/9416004" }, { "database": "PubMed", "id": "9922457", "url": "https://pubmed.ncbi.nlm.nih.gov/9922457" }, { "database": "PubMed", "id": "15561106", "url": "https://pubmed.ncbi.nlm.nih.gov/15561106" }, { "database": "PubMed", "id": "19339212", "url": "https://pubmed.ncbi.nlm.nih.gov/19339212" }, { "database": "PubMed", "id": "19369195", "url": "https://pubmed.ncbi.nlm.nih.gov/19369195" } ], "site_lbl": "Tyr397", "uniprot_canonical_ac": "Q05397-1" } ], "record_id": "pubmed.12021278", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Solution structure of the human Grb7-SH2 domain/erbB2 peptide complex and structural basis for Grb7 binding to ErbB2.", "journal": "J. Biomol. NMR", "date": "2003", "authors": "Ivancic Monika, Daly Roger J, Lyons Barbara A", "reference": { "type": "PubMed", "id": "12975581", "url": "https://pubmed.ncbi.nlm.nih.gov/12975581" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12975581", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation sites in the PDGF receptor with different specificities for binding GAP and PI3 kinase in vivo.", "journal": "The EMBO journal", "date": "1992", "authors": "Kashishian A, Kazlauskas A, Cooper JA", "reference": { "type": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 634, "end_pos": 634, "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of kinase activity. Abolishes interaction with RASA1. No effect on phosphatidylinositol 3-kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1846866", "url": "https://pubmed.ncbi.nlm.nih.gov/1846866" }, { "database": "PubMed", "id": "20494825", "url": "https://pubmed.ncbi.nlm.nih.gov/20494825" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 634, "end_pos": 634, "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of kinase activity. Abolishes interaction with RASA1. No effect on phosphatidylinositol 3-kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1846866", "url": "https://pubmed.ncbi.nlm.nih.gov/1846866" }, { "database": "PubMed", "id": "20494825", "url": "https://pubmed.ncbi.nlm.nih.gov/20494825" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 716, "end_pos": 716, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect neither on interaction with GRB10 and RASA1 nor on phosphatidylinositol 3-kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 740, "end_pos": 740, "sequence_org": "Y", "sequence_mut": "F", "comment": "Strongly reduces up-regulation of cell proliferation; when associated with F-751. Strongly decreases phosphatidylinositol 3-kinase activity. No effect on interaction with GRB10 and RASA1.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "21679854", "url": "https://pubmed.ncbi.nlm.nih.gov/21679854" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 751, "end_pos": 751, "sequence_org": "Y", "sequence_mut": "F", "comment": "Strongly reduces up-regulation of cell proliferation; when associated with F-740. Abolishes phosphatidylinositol 3-kinase activity and interaction with NCK1, and slightly reduces interaction with RASA1. No effect on interaction with GRB10.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "21679854", "url": "https://pubmed.ncbi.nlm.nih.gov/21679854" }, { "database": "PubMed", "id": "1653029", "url": "https://pubmed.ncbi.nlm.nih.gov/1653029" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "7692233", "url": "https://pubmed.ncbi.nlm.nih.gov/7692233" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 763, "end_pos": 763, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect on interaction with RASA1 and on phosphatidylinositol 3-kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 771, "end_pos": 771, "sequence_org": "Y", "sequence_mut": "F", "comment": "Loss of interaction with GRB10. Abolishes interaction with RASA1. No effect on phosphatidylinositol 3-kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 775, "end_pos": 775, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect on interaction with RASA1 and on phosphatidylinositol 3-kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 778, "end_pos": 778, "sequence_org": "Y", "sequence_mut": "F", "comment": "Strongly reduces expression levels.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 857, "end_pos": 857, "sequence_org": "Y", "sequence_mut": "F", "comment": "Reduces kinase activity. No effect on interaction with GRB10. Abolishes interaction with RASA1. No effect on phosphatidylinositol 3-kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "20494825", "url": "https://pubmed.ncbi.nlm.nih.gov/20494825" }, { "database": "PubMed", "id": "1653029", "url": "https://pubmed.ncbi.nlm.nih.gov/1653029" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" } ], "uniprot_canonical_ac": "P09619-1" } ], "phosphorylation": [ { "start_pos": 740, "end_pos": 740, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "8195171", "url": "https://pubmed.ncbi.nlm.nih.gov/8195171" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" } ], "site_lbl": "Tyr740", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 740, "end_pos": 740, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "1330535", "url": "https://pubmed.ncbi.nlm.nih.gov/1330535" }, { "database": "PubMed", "id": "10752619", "url": "https://pubmed.ncbi.nlm.nih.gov/10752619" }, { "database": "PubMed", "id": "11710529", "url": "https://pubmed.ncbi.nlm.nih.gov/11710529" }, { "database": "PubMed", "id": "11896612", "url": "https://pubmed.ncbi.nlm.nih.gov/11896612" }, { "database": "PubMed", "id": "7683666", "url": "https://pubmed.ncbi.nlm.nih.gov/7683666" }, { "database": "PubMed", "id": "7876130", "url": "https://pubmed.ncbi.nlm.nih.gov/7876130" }, { "database": "PubMed", "id": "8382612", "url": "https://pubmed.ncbi.nlm.nih.gov/8382612" }, { "database": "PubMed", "id": "8382774", "url": "https://pubmed.ncbi.nlm.nih.gov/8382774" }, { "database": "PubMed", "id": "8670861", "url": "https://pubmed.ncbi.nlm.nih.gov/8670861" }, { "database": "PubMed", "id": "9512716", "url": "https://pubmed.ncbi.nlm.nih.gov/9512716" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "17403678", "url": "https://pubmed.ncbi.nlm.nih.gov/17403678" }, { "database": "PubMed", "id": "15902258", "url": "https://pubmed.ncbi.nlm.nih.gov/15902258" } ], "site_lbl": "Tyr740", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 751, "end_pos": 751, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "10336465", "url": "https://pubmed.ncbi.nlm.nih.gov/10336465" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "1330535", "url": "https://pubmed.ncbi.nlm.nih.gov/1330535" }, { "database": "PubMed", "id": "10752619", "url": "https://pubmed.ncbi.nlm.nih.gov/10752619" }, { "database": "PubMed", "id": "11710529", "url": "https://pubmed.ncbi.nlm.nih.gov/11710529" }, { "database": "PubMed", "id": "7536927", "url": "https://pubmed.ncbi.nlm.nih.gov/7536927" }, { "database": "PubMed", "id": "7680644", "url": "https://pubmed.ncbi.nlm.nih.gov/7680644" }, { "database": "PubMed", "id": "7683666", "url": "https://pubmed.ncbi.nlm.nih.gov/7683666" }, { "database": "PubMed", "id": "7692233", "url": "https://pubmed.ncbi.nlm.nih.gov/7692233" }, { "database": "PubMed", "id": "7876130", "url": "https://pubmed.ncbi.nlm.nih.gov/7876130" }, { "database": "PubMed", "id": "9153411", "url": "https://pubmed.ncbi.nlm.nih.gov/9153411" }, { "database": "PubMed", "id": "8382774", "url": "https://pubmed.ncbi.nlm.nih.gov/8382774" }, { "database": "PubMed", "id": "8564419", "url": "https://pubmed.ncbi.nlm.nih.gov/8564419" }, { "database": "PubMed", "id": "8670861", "url": "https://pubmed.ncbi.nlm.nih.gov/8670861" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "17403678", "url": "https://pubmed.ncbi.nlm.nih.gov/17403678" }, { "database": "PubMed", "id": "17961557", "url": "https://pubmed.ncbi.nlm.nih.gov/17961557" }, { "database": "PubMed", "id": "18567737", "url": "https://pubmed.ncbi.nlm.nih.gov/18567737" }, { "database": "PubMed", "id": "2170111", "url": "https://pubmed.ncbi.nlm.nih.gov/2170111" }, { "database": "PubMed", "id": "24648957", "url": "https://pubmed.ncbi.nlm.nih.gov/24648957" }, { "database": "PubMed", "id": "28487538", "url": "https://pubmed.ncbi.nlm.nih.gov/28487538" }, { "database": "PubMed", "id": "33093618", "url": "https://pubmed.ncbi.nlm.nih.gov/33093618" }, { "database": "PubMed", "id": "33509954", "url": "https://pubmed.ncbi.nlm.nih.gov/33509954" }, { "database": "PubMed", "id": "14966296", "url": "https://pubmed.ncbi.nlm.nih.gov/14966296" }, { "database": "PubMed", "id": "1709159", "url": "https://pubmed.ncbi.nlm.nih.gov/1709159" }, { "database": "PubMed", "id": "2550144", "url": "https://pubmed.ncbi.nlm.nih.gov/2550144" } ], "site_lbl": "Tyr751", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 771, "end_pos": 771, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "8195171", "url": "https://pubmed.ncbi.nlm.nih.gov/8195171" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "10821867", "url": "https://pubmed.ncbi.nlm.nih.gov/10821867" } ], "site_lbl": "Tyr771", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 771, "end_pos": 771, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "10733900", "url": "https://pubmed.ncbi.nlm.nih.gov/10733900" }, { "database": "PubMed", "id": "8382774", "url": "https://pubmed.ncbi.nlm.nih.gov/8382774" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "26631574", "url": "https://pubmed.ncbi.nlm.nih.gov/26631574" }, { "database": "PubMed", "id": "33509954", "url": "https://pubmed.ncbi.nlm.nih.gov/33509954" }, { "database": "PubMed", "id": "14966296", "url": "https://pubmed.ncbi.nlm.nih.gov/14966296" }, { "database": "PubMed", "id": "15902258", "url": "https://pubmed.ncbi.nlm.nih.gov/15902258" } ], "site_lbl": "Tyr771", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 857, "end_pos": 857, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "1661130", "url": "https://pubmed.ncbi.nlm.nih.gov/1661130" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "15271984", "url": "https://pubmed.ncbi.nlm.nih.gov/15271984" }, { "database": "PubMed", "id": "15994317", "url": "https://pubmed.ncbi.nlm.nih.gov/15994317" }, { "database": "PubMed", "id": "1653029", "url": "https://pubmed.ncbi.nlm.nih.gov/1653029" }, { "database": "PubMed", "id": "9642269", "url": "https://pubmed.ncbi.nlm.nih.gov/9642269" }, { "database": "PubMed", "id": "24165129", "url": "https://pubmed.ncbi.nlm.nih.gov/24165129" }, { "database": "PubMed", "id": "26104298", "url": "https://pubmed.ncbi.nlm.nih.gov/26104298" }, { "database": "PubMed", "id": "34360683", "url": "https://pubmed.ncbi.nlm.nih.gov/34360683" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "15902258", "url": "https://pubmed.ncbi.nlm.nih.gov/15902258" }, { "database": "PubMed", "id": "1709159", "url": "https://pubmed.ncbi.nlm.nih.gov/1709159" }, { "database": "PubMed", "id": "2550144", "url": "https://pubmed.ncbi.nlm.nih.gov/2550144" } ], "site_lbl": "Tyr857", "uniprot_canonical_ac": "P09619-1" } ], "record_id": "pubmed.1314164", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 4 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Distinct phosphotyrosines on a growth factor receptor bind to specific molecules that mediate different signaling pathways.", "journal": "Cell", "date": "1992", "authors": "Fantl WJ, Escobedo JA, Martin GA, Turck CW, del Rosario M, McCormick F, Williams LT", "reference": { "type": "PubMed", "id": "1374684", "url": "https://pubmed.ncbi.nlm.nih.gov/1374684" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1374684", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "GTPase-activating protein and phosphatidylinositol 3-kinase bind to distinct regions of the platelet-derived growth factor receptor beta subunit.", "journal": "Molecular and cellular biology", "date": "1992", "authors": "Kazlauskas A, Kashishian A, Cooper JA, Valius M", "reference": { "type": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23727-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Bovine" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 740, "end_pos": 740, "sequence_org": "Y", "sequence_mut": "F", "comment": "Strongly reduces up-regulation of cell proliferation; when associated with F-751. Strongly decreases phosphatidylinositol 3-kinase activity. No effect on interaction with GRB10 and RASA1.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "21679854", "url": "https://pubmed.ncbi.nlm.nih.gov/21679854" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 751, "end_pos": 751, "sequence_org": "Y", "sequence_mut": "F", "comment": "Strongly reduces up-regulation of cell proliferation; when associated with F-740. Abolishes phosphatidylinositol 3-kinase activity and interaction with NCK1, and slightly reduces interaction with RASA1. No effect on interaction with GRB10.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "21679854", "url": "https://pubmed.ncbi.nlm.nih.gov/21679854" }, { "database": "PubMed", "id": "1653029", "url": "https://pubmed.ncbi.nlm.nih.gov/1653029" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "7692233", "url": "https://pubmed.ncbi.nlm.nih.gov/7692233" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 771, "end_pos": 771, "sequence_org": "Y", "sequence_mut": "F", "comment": "Loss of interaction with GRB10. Abolishes interaction with RASA1. No effect on phosphatidylinositol 3-kinase activity.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" } ], "uniprot_canonical_ac": "P09619-1" } ], "phosphorylation": [ { "start_pos": 740, "end_pos": 740, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "8195171", "url": "https://pubmed.ncbi.nlm.nih.gov/8195171" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" } ], "site_lbl": "Tyr740", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 751, "end_pos": 751, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "8195171", "url": "https://pubmed.ncbi.nlm.nih.gov/8195171" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" }, { "database": "PubMed", "id": "2550144", "url": "https://pubmed.ncbi.nlm.nih.gov/2550144" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "10821867", "url": "https://pubmed.ncbi.nlm.nih.gov/10821867" } ], "site_lbl": "Tyr751", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 771, "end_pos": 771, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "8195171", "url": "https://pubmed.ncbi.nlm.nih.gov/8195171" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "10821867", "url": "https://pubmed.ncbi.nlm.nih.gov/10821867" } ], "site_lbl": "Tyr771", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 771, "end_pos": 771, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "10733900", "url": "https://pubmed.ncbi.nlm.nih.gov/10733900" }, { "database": "PubMed", "id": "8382774", "url": "https://pubmed.ncbi.nlm.nih.gov/8382774" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "26631574", "url": "https://pubmed.ncbi.nlm.nih.gov/26631574" }, { "database": "PubMed", "id": "33509954", "url": "https://pubmed.ncbi.nlm.nih.gov/33509954" }, { "database": "PubMed", "id": "14966296", "url": "https://pubmed.ncbi.nlm.nih.gov/14966296" }, { "database": "PubMed", "id": "15902258", "url": "https://pubmed.ncbi.nlm.nih.gov/15902258" } ], "site_lbl": "Tyr771", "uniprot_canonical_ac": "P09619-1" } ], "record_id": "pubmed.1375321", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 27 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of two C-terminal autophosphorylation sites in the PDGF beta-receptor: involvement in the interaction with phospholipase C-gamma.", "journal": "The EMBO journal", "date": "1992", "authors": "Ronnstrand L, Mori S, Arridsson AK, Eriksson A, Wernstedt C, Hellman U, Claesson-Welsh L, Heldin CH", "reference": { "type": "PubMed", "id": "1396585", "url": "https://pubmed.ncbi.nlm.nih.gov/1396585" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1009, "end_pos": 1009, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect on interaction with GRB10. Abolishes interaction with PLCG1; when associated with F-1021.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1396585", "url": "https://pubmed.ncbi.nlm.nih.gov/1396585" }, { "database": "PubMed", "id": "7691811", "url": "https://pubmed.ncbi.nlm.nih.gov/7691811" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 1021, "end_pos": 1021, "sequence_org": "Y", "sequence_mut": "F", "comment": "Strongly reduces up-regulation of cell proliferation. Abolishes interaction with PLCG1; when associated with F-1009. No effect on interaction with GRB10.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "21679854", "url": "https://pubmed.ncbi.nlm.nih.gov/21679854" }, { "database": "PubMed", "id": "1396585", "url": "https://pubmed.ncbi.nlm.nih.gov/1396585" }, { "database": "PubMed", "id": "17620338", "url": "https://pubmed.ncbi.nlm.nih.gov/17620338" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" } ], "uniprot_canonical_ac": "P09619-1" } ], "phosphorylation": [ { "start_pos": 1009, "end_pos": 1009, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "8195171", "url": "https://pubmed.ncbi.nlm.nih.gov/8195171" }, { "database": "PubMed", "id": "7678051", "url": "https://pubmed.ncbi.nlm.nih.gov/7678051" }, { "database": "PubMed", "id": "1396585", "url": "https://pubmed.ncbi.nlm.nih.gov/1396585" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "10821867", "url": "https://pubmed.ncbi.nlm.nih.gov/10821867" } ], "site_lbl": "Tyr1009", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 1009, "end_pos": 1009, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "1396585", "url": "https://pubmed.ncbi.nlm.nih.gov/1396585" }, { "database": "PubMed", "id": "11027258", "url": "https://pubmed.ncbi.nlm.nih.gov/11027258" }, { "database": "PubMed", "id": "7530043", "url": "https://pubmed.ncbi.nlm.nih.gov/7530043" }, { "database": "PubMed", "id": "8183548", "url": "https://pubmed.ncbi.nlm.nih.gov/8183548" }, { "database": "PubMed", "id": "8538796", "url": "https://pubmed.ncbi.nlm.nih.gov/8538796" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "17403678", "url": "https://pubmed.ncbi.nlm.nih.gov/17403678" }, { "database": "PubMed", "id": "25569182", "url": "https://pubmed.ncbi.nlm.nih.gov/25569182" }, { "database": "PubMed", "id": "33509954", "url": "https://pubmed.ncbi.nlm.nih.gov/33509954" }, { "database": "PubMed", "id": "7678051", "url": "https://pubmed.ncbi.nlm.nih.gov/7678051" }, { "database": "PubMed", "id": "7688466", "url": "https://pubmed.ncbi.nlm.nih.gov/7688466" }, { "database": "PubMed", "id": "15902258", "url": "https://pubmed.ncbi.nlm.nih.gov/15902258" } ], "site_lbl": "Tyr1009", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 1021, "end_pos": 1021, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "12062403", "url": "https://pubmed.ncbi.nlm.nih.gov/12062403" }, { "database": "PubMed", "id": "7678051", "url": "https://pubmed.ncbi.nlm.nih.gov/7678051" }, { "database": "PubMed", "id": "1396585", "url": "https://pubmed.ncbi.nlm.nih.gov/1396585" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "10821867", "url": "https://pubmed.ncbi.nlm.nih.gov/10821867" } ], "site_lbl": "Tyr1021", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 1021, "end_pos": 1021, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "1396585", "url": "https://pubmed.ncbi.nlm.nih.gov/1396585" }, { "database": "PubMed", "id": "10373546", "url": "https://pubmed.ncbi.nlm.nih.gov/10373546" }, { "database": "PubMed", "id": "15641795", "url": "https://pubmed.ncbi.nlm.nih.gov/15641795" }, { "database": "PubMed", "id": "17620338", "url": "https://pubmed.ncbi.nlm.nih.gov/17620338" }, { "database": "PubMed", "id": "11896612", "url": "https://pubmed.ncbi.nlm.nih.gov/11896612" }, { "database": "PubMed", "id": "7678051", "url": "https://pubmed.ncbi.nlm.nih.gov/7678051" }, { "database": "PubMed", "id": "7876130", "url": "https://pubmed.ncbi.nlm.nih.gov/7876130" }, { "database": "PubMed", "id": "8119896", "url": "https://pubmed.ncbi.nlm.nih.gov/8119896" }, { "database": "PubMed", "id": "8181064", "url": "https://pubmed.ncbi.nlm.nih.gov/8181064" }, { "database": "PubMed", "id": "8555205", "url": "https://pubmed.ncbi.nlm.nih.gov/8555205" }, { "database": "PubMed", "id": "9989826", "url": "https://pubmed.ncbi.nlm.nih.gov/9989826" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "26104298", "url": "https://pubmed.ncbi.nlm.nih.gov/26104298" }, { "database": "PubMed", "id": "26631574", "url": "https://pubmed.ncbi.nlm.nih.gov/26631574" }, { "database": "PubMed", "id": "27048651", "url": "https://pubmed.ncbi.nlm.nih.gov/27048651" }, { "database": "PubMed", "id": "33509954", "url": "https://pubmed.ncbi.nlm.nih.gov/33509954" }, { "database": "PubMed", "id": "14966296", "url": "https://pubmed.ncbi.nlm.nih.gov/14966296" }, { "database": "PubMed", "id": "15902258", "url": "https://pubmed.ncbi.nlm.nih.gov/15902258" } ], "site_lbl": "Tyr1021", "uniprot_canonical_ac": "P09619-1" } ], "record_id": "pubmed.1396585", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Adaptor ShcA protein binds tyrosine kinase Tie2 receptor and regulates migration and sprouting but not survival of endothelial cells.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Audero E, Cascone I, Maniero F, Napione L, Arese M, Lanfrancone L, Bussolino F", "reference": { "type": "PubMed", "id": "14665640", "url": "https://pubmed.ncbi.nlm.nih.gov/14665640" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1102, "end_pos": 1102, "sequence_org": "Y", "sequence_mut": "F", "comment": "Abolishes interaction with SHC1.", "evidence": [ { "database": "UniProtKB", "id": "Q02763", "url": "https://www.uniprot.org/uniprotkb/Q02763" }, { "database": "PubMed", "id": "14665640", "url": "https://pubmed.ncbi.nlm.nih.gov/14665640" } ], "uniprot_canonical_ac": "Q02763-1" } ], "phosphorylation": [ { "start_pos": 1080, "end_pos": 1080, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "IntAct", "id": "Q02763", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q02763*" }, { "database": "iPTMnet", "id": "Q02763", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02763" }, { "database": "PubMed", "id": "14665640", "url": "https://pubmed.ncbi.nlm.nih.gov/14665640" } ], "site_lbl": "Tyr1080", "uniprot_canonical_ac": "Q02763-1" }, { "start_pos": 1102, "end_pos": 1102, "kinase_uniprot_canonical_ac": "Q02763-1", "kinase_gene_name": "TEK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q02763", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02763" }, { "database": "PubMed", "id": "10521483", "url": "https://pubmed.ncbi.nlm.nih.gov/10521483" }, { "database": "PubMed", "id": "9632797", "url": "https://pubmed.ncbi.nlm.nih.gov/9632797" }, { "database": "PubMed", "id": "20973951", "url": "https://pubmed.ncbi.nlm.nih.gov/20973951" }, { "database": "UniProtKB", "id": "Q02763", "url": "https://www.uniprot.org/uniprotkb/Q02763" }, { "database": "PubMed", "id": "14665640", "url": "https://pubmed.ncbi.nlm.nih.gov/14665640" } ], "site_lbl": "Tyr1102", "uniprot_canonical_ac": "Q02763-1" } ], "record_id": "pubmed.14665640", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional significance of Tie2 signaling in the adult vasculature.", "journal": "Recent progress in hormone research", "date": "2004", "authors": "Peters KG, Kontos CD, Lin PC, Wong AL, Rao P, Huang L, Dewhirst MW, Sankar S", "reference": { "type": "PubMed", "id": "14749497", "url": "https://pubmed.ncbi.nlm.nih.gov/14749497" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14749497", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Grb7-SH2 domain dimerisation is affected by a single point mutation.", "journal": "European biophysics journal : EBJ", "date": "2005", "authors": "Porter CJ, Wilce MC, Mackay JP, Leedman P, Wilce JA", "reference": { "type": "PubMed", "id": "15841400", "url": "https://pubmed.ncbi.nlm.nih.gov/15841400" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 511, "end_pos": 511, "sequence_org": "F", "sequence_mut": "R", "comment": "Abolishes dimerization. Abolishes activation of HRAS.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "15841400", "url": "https://pubmed.ncbi.nlm.nih.gov/15841400" } ], "uniprot_canonical_ac": "Q14451-1" } ], "record_id": "pubmed.15841400", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure of the angiopoietin-2 receptor binding domain and identification of surfaces involved in Tie2 recognition.", "journal": "Structure (London, England : 1993)", "date": "2005", "authors": "Barton WA, Tzvetkova D, Nikolov DB", "reference": { "type": "PubMed", "id": "15893672", "url": "https://pubmed.ncbi.nlm.nih.gov/15893672" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15893672", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Activation of Tie2 by angiopoietin-1 and angiopoietin-2 results in their release and receptor internalization.", "journal": "Journal of cell science", "date": "2006", "authors": "Bogdanovic E, Nguyen VP, Dumont DJ", "reference": { "type": "PubMed", "id": "16895971", "url": "https://pubmed.ncbi.nlm.nih.gov/16895971" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16895971", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation.", "journal": "BMC Struct. Biol.", "date": "2007", "authors": "Porter Corrine J, Matthews Jacqueline M, Mackay Joel P, Pursglove Sharon E, Schmidberger Jason W, Leedman Peter J, Pero Stephanie C, Krag David N, Wilce Matthew C J, Wilce Jacqueline A", "reference": { "type": "PubMed", "id": "17894853", "url": "https://pubmed.ncbi.nlm.nih.gov/17894853" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17894853", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The cell migration protein Grb7 associates with transcriptional regulator FHL2 in a Grb7 phosphorylation-dependent manner.", "journal": "Journal of molecular recognition : JMR", "date": "2009", "authors": "Siamakpour-Reihani S, Argiros HJ, Wilmeth LJ, Haas LL, Peterson TA, Johnson DL, Shuster CB, Lyons BA", "reference": { "type": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14192-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "FHL2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 259, "end_pos": 259, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 260, "end_pos": 260, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 284, "end_pos": 284, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 480, "end_pos": 480, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 492, "end_pos": 492, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" } ], "record_id": "pubmed.18853468", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tyrosine phosphorylation of growth factor receptor-bound protein-7 by focal adhesion kinase in the regulation of cell migration, proliferation, and tumorigenesis.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Chu PY, Huang LY, Hsu CH, Liang CC, Guan JL, Hung TH, Shen TL", "reference": { "type": "PubMed", "id": "19473962", "url": "https://pubmed.ncbi.nlm.nih.gov/19473962" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P34152-3", "protein_name": "Focal adhesion kinase 1", "gene_name": "Ptk2", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 188, "end_pos": 188, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by FAK1", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "iPTMnet", "id": "Q14451", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14451" }, { "database": "PubMed", "id": "20622016", "url": "https://pubmed.ncbi.nlm.nih.gov/20622016" }, { "database": "PubMed", "id": "19473962", "url": "https://pubmed.ncbi.nlm.nih.gov/19473962" } ], "site_lbl": "Tyr188", "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 338, "end_pos": 338, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by FAK1", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "iPTMnet", "id": "Q14451", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14451" }, { "database": "PubMed", "id": "20622016", "url": "https://pubmed.ncbi.nlm.nih.gov/20622016" }, { "database": "PubMed", "id": "19473962", "url": "https://pubmed.ncbi.nlm.nih.gov/19473962" } ], "site_lbl": "Tyr338", "uniprot_canonical_ac": "Q14451-1" } ], "record_id": "pubmed.19473962", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "EGF-induced Grb7 recruits and promotes Ras activity essential for the tumorigenicity of Sk-Br3 breast cancer cells.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Chu PY, Li TK, Ding ST, Lai IR, Shen TL", "reference": { "type": "PubMed", "id": "20622016", "url": "https://pubmed.ncbi.nlm.nih.gov/20622016" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 188, "end_pos": 188, "sequence_org": "Y", "sequence_mut": "F", "comment": "Abolishes Ras activity increase and ERK1/2 phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20622016", "url": "https://pubmed.ncbi.nlm.nih.gov/20622016" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 338, "end_pos": 338, "sequence_org": "Y", "sequence_mut": "F", "comment": "Abolishes Ras activity increase and ERK1/2 phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20622016", "url": "https://pubmed.ncbi.nlm.nih.gov/20622016" } ], "uniprot_canonical_ac": "Q14451-1" } ], "phosphorylation": [ { "start_pos": 188, "end_pos": 188, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by FAK1", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "iPTMnet", "id": "Q14451", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14451" }, { "database": "PubMed", "id": "20622016", "url": "https://pubmed.ncbi.nlm.nih.gov/20622016" }, { "database": "PubMed", "id": "19473962", "url": "https://pubmed.ncbi.nlm.nih.gov/19473962" } ], "site_lbl": "Tyr188", "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 338, "end_pos": 338, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by FAK1", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "iPTMnet", "id": "Q14451", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14451" }, { "database": "PubMed", "id": "20622016", "url": "https://pubmed.ncbi.nlm.nih.gov/20622016" }, { "database": "PubMed", "id": "19473962", "url": "https://pubmed.ncbi.nlm.nih.gov/19473962" } ], "site_lbl": "Tyr338", "uniprot_canonical_ac": "Q14451-1" } ], "record_id": "pubmed.20622016", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Grb7 binds to Hax-1 and undergoes an intramolecular domain association that offers a model for Grb7 regulation.", "journal": "Journal of molecular recognition : JMR", "date": "2011", "authors": "Siamakpour-Reihani S, Peterson TA, Bradford AM, Argiros HJ, Haas LL, Lor SN, Haulsee ZM, Spuches AM, Johnson DL, Rohrschneider LR, Shuster CB, Lyons BA", "reference": { "type": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00165-1", "protein_name": "HCLS1-associated protein X-1", "gene_name": "HAX1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 259, "end_pos": 259, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 260, "end_pos": 260, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 284, "end_pos": 284, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 480, "end_pos": 480, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" }, { "start_pos": 492, "end_pos": 492, "sequence_org": "Y", "sequence_mut": "F", "comment": "Global loss of tyrosine phosphorylation. Abolishes interaction with FHL2 and HAX1.", "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" }, { "database": "PubMed", "id": "20665473", "url": "https://pubmed.ncbi.nlm.nih.gov/20665473" }, { "database": "PubMed", "id": "18853468", "url": "https://pubmed.ncbi.nlm.nih.gov/18853468" } ], "uniprot_canonical_ac": "Q14451-1" } ], "record_id": "pubmed.20665473", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Role of phosphatidylinositol kinase in PDGF receptor signal transduction.", "journal": "Science (New York, N.Y.)", "date": "1989", "authors": "Coughlin SR, Escobedo JA, Williams LT", "reference": { "type": "PubMed", "id": "2466336", "url": "https://pubmed.ncbi.nlm.nih.gov/2466336" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2466336", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Grb7 Protein Stability Modulated by Pin1 in Association with Cell Cycle Progression.", "journal": "PloS one", "date": "2016", "authors": "Tai YL, Tung LH, Lin YC, Lu PJ, Chu PY, Wang MY, Huang WP, Chen KC, Lee H, Shen TL", "reference": { "type": "PubMed", "id": "27658202", "url": "https://pubmed.ncbi.nlm.nih.gov/27658202" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 194, "end_pos": 194, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14451", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14451" }, { "database": "PubMed", "id": "27658202", "url": "https://pubmed.ncbi.nlm.nih.gov/27658202" } ], "site_lbl": "Ser194", "uniprot_canonical_ac": "Q14451-1" } ], "record_id": "pubmed.27658202", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Growth factor receptor bound protein-7 regulates proliferation, cell cycle, and mitochondrial apoptosis of thyroid cancer cells via MAPK/ERK signaling.", "journal": "Molecular and cellular biochemistry", "date": "2020", "authors": "Tang H, Yang P, Yang X, Peng S, Hu X, Bao G", "reference": { "type": "PubMed", "id": "32577949", "url": "https://pubmed.ncbi.nlm.nih.gov/32577949" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.32577949", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "GRB7 is an oncogenic driver and potential therapeutic target in oesophageal adenocarcinoma.", "journal": "The Journal of pathology", "date": "2020", "authors": "Gotovac JR, Liu DS, Yates MJ, Milne JV, Macpherson AA, Simpson KJ, Eslick GD, Mitchell C, Duong CP, Phillips WA, Clemons NJ", "reference": { "type": "PubMed", "id": "32737994", "url": "https://pubmed.ncbi.nlm.nih.gov/32737994" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.32737994", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Upregulated GRB7 promotes proliferation and tumorigenesis of Bladder Cancer via Phospho-AKT Pathway.", "journal": "International journal of biological sciences", "date": "2020", "authors": "Zheng Y, Pei Y, Yang L, Zeng Z, Wang J, Xie G, Wang L, Yuan J", "reference": { "type": "PubMed", "id": "33162827", "url": "https://pubmed.ncbi.nlm.nih.gov/33162827" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33162827", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Knockdown of growth factor receptor bound protein 7 suppresses angiogenesis by inhibiting the secretion of vascular endothelial growth factor A in ovarian cancer cells.", "journal": "Bioengineered", "date": "2021", "authors": "Xu Q, Liu Z, Zhu ZQ, Fan Y, Chen R, Xie XH, Cheng M", "reference": { "type": "PubMed", "id": "34783299", "url": "https://pubmed.ncbi.nlm.nih.gov/34783299" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34783299", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Follicular cells protect Xenopus oocyte from abnormal maturation via integrin signaling downregulation and O-GlcNAcylation control.", "journal": "The Journal of biological chemistry", "date": "2023-08", "authors": "Martoriati Alain, Molinaro Caroline, Marchand Guillaume, Fliniaux Ingrid, Marin Matthieu, Bodart Jean-Fran\u00e7ois, Takeda-Uchimura Yoshiko, Lefebvre Tony, Dehennaut Vanessa, Cailliau Katia", "reference": { "type": "PubMed", "id": "37354972", "url": "https://pubmed.ncbi.nlm.nih.gov/37354972" }, "referenced_glycans": [ { "glytoucan_ac": "G49108TO" } ], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "29485866", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/29485866" }, { "id": "Q14451", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q14451" }, { "id": "37354972", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/37354972" } ], "filter_code": "000000000000000000000.xxxxxxx.00000001000000.xxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxxxxxx.xxxxx.01000", "uniprot_canonical_ac": "Q14451-1" } ], "record_id": "pubmed.37354972", "abstract": "", "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "glytoucan_ac" ] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "GRB7 plays a promoting role in the progression of gastric cancer.", "journal": "BMC cancer", "date": "2023-12-21", "authors": "Zhu Guomin, Cai Hu, Xiao Qiang, Zeng Shukun, Jiang Xiaohua, Liu Donglan", "reference": { "type": "PubMed", "id": "38129809", "url": "https://pubmed.ncbi.nlm.nih.gov/38129809" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38129809", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "GRB2 and SH-PTP2: potentially important endothelial signaling molecules downstream of the TEK/TIE2 receptor tyrosine kinase.", "journal": "Oncogene", "date": "1995", "authors": "Huang L, Turck CW, Rao P, Peters KG", "reference": { "type": "PubMed", "id": "7478529", "url": "https://pubmed.ncbi.nlm.nih.gov/7478529" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7478529", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of two juxtamembrane autophosphorylation sites in the PDGF beta-receptor; involvement in the interaction with Src family tyrosine kinases.", "journal": "The EMBO journal", "date": "1993", "authors": "Mori S, Ronnstrand L, Yokote K, Engstrom A, Courtneidge SA, Claesson-Welsh L, Heldin CH", "reference": { "type": "PubMed", "id": "7685273", "url": "https://pubmed.ncbi.nlm.nih.gov/7685273" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 579, "end_pos": 579, "sequence_org": "Y", "sequence_mut": "F", "comment": "Loss of kinase activity; when associated with F-581. Strongly reduces interaction with SRC family kinases. No effect on interaction with GRB10.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "7685273", "url": "https://pubmed.ncbi.nlm.nih.gov/7685273" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" } ], "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 581, "end_pos": 581, "sequence_org": "Y", "sequence_mut": "F", "comment": "Loss of kinase activity; when associated with F-579. No effect on interaction with GRB10.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "7685273", "url": "https://pubmed.ncbi.nlm.nih.gov/7685273" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" } ], "uniprot_canonical_ac": "P09619-1" } ], "phosphorylation": [ { "start_pos": 579, "end_pos": 579, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "7685273", "url": "https://pubmed.ncbi.nlm.nih.gov/7685273" }, { "database": "PubMed", "id": "7687537", "url": "https://pubmed.ncbi.nlm.nih.gov/7687537" }, { "database": "PubMed", "id": "12706723", "url": "https://pubmed.ncbi.nlm.nih.gov/12706723" }, { "database": "PubMed", "id": "9742401", "url": "https://pubmed.ncbi.nlm.nih.gov/9742401" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "24165129", "url": "https://pubmed.ncbi.nlm.nih.gov/24165129" }, { "database": "PubMed", "id": "34360683", "url": "https://pubmed.ncbi.nlm.nih.gov/34360683" }, { "database": "PubMed", "id": "15902258", "url": "https://pubmed.ncbi.nlm.nih.gov/15902258" } ], "site_lbl": "Tyr579", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 581, "end_pos": 581, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "7685273", "url": "https://pubmed.ncbi.nlm.nih.gov/7685273" }, { "database": "PubMed", "id": "12706723", "url": "https://pubmed.ncbi.nlm.nih.gov/12706723" }, { "database": "PubMed", "id": "9742401", "url": "https://pubmed.ncbi.nlm.nih.gov/9742401" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" } ], "site_lbl": "Tyr581", "uniprot_canonical_ac": "P09619-1" } ], "record_id": "pubmed.7685273", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Activation of the SH2-containing phosphotyrosine phosphatase SH-PTP2 by its binding site, phosphotyrosine 1009, on the human platelet-derived growth factor receptor.", "journal": "The Journal of biological chemistry", "date": "1993", "authors": "Lechleider RJ, Sugimoto S, Bennett AM, Kashishian AS, Cooper JA, Shoelson SE, Walsh CT, Neel BG", "reference": { "type": "PubMed", "id": "7691811", "url": "https://pubmed.ncbi.nlm.nih.gov/7691811" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1009, "end_pos": 1009, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect on interaction with GRB10. Abolishes interaction with PLCG1; when associated with F-1021.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "1396585", "url": "https://pubmed.ncbi.nlm.nih.gov/1396585" }, { "database": "PubMed", "id": "7691811", "url": "https://pubmed.ncbi.nlm.nih.gov/7691811" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" } ], "uniprot_canonical_ac": "P09619-1" } ], "record_id": "pubmed.7691811", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Two signaling molecules share a phosphotyrosine-containing binding site in the platelet-derived growth factor receptor.", "journal": "Molecular and cellular biology", "date": "1993", "authors": "Nishimura R, Li W, Kashishian A, Mondino A, Zhou M, Cooper J, Schlessinger J", "reference": { "type": "PubMed", "id": "7692233", "url": "https://pubmed.ncbi.nlm.nih.gov/7692233" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 751, "end_pos": 751, "sequence_org": "Y", "sequence_mut": "F", "comment": "Strongly reduces up-regulation of cell proliferation; when associated with F-740. Abolishes phosphatidylinositol 3-kinase activity and interaction with NCK1, and slightly reduces interaction with RASA1. No effect on interaction with GRB10.", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "21679854", "url": "https://pubmed.ncbi.nlm.nih.gov/21679854" }, { "database": "PubMed", "id": "1653029", "url": "https://pubmed.ncbi.nlm.nih.gov/1653029" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "7692233", "url": "https://pubmed.ncbi.nlm.nih.gov/7692233" }, { "database": "PubMed", "id": "10454568", "url": "https://pubmed.ncbi.nlm.nih.gov/10454568" }, { "database": "PubMed", "id": "1375321", "url": "https://pubmed.ncbi.nlm.nih.gov/1375321" } ], "uniprot_canonical_ac": "P09619-1" } ], "phosphorylation": [ { "start_pos": 751, "end_pos": 751, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "10336465", "url": "https://pubmed.ncbi.nlm.nih.gov/10336465" }, { "database": "PubMed", "id": "1314164", "url": "https://pubmed.ncbi.nlm.nih.gov/1314164" }, { "database": "PubMed", "id": "1330535", "url": "https://pubmed.ncbi.nlm.nih.gov/1330535" }, { "database": "PubMed", "id": "10752619", "url": "https://pubmed.ncbi.nlm.nih.gov/10752619" }, { "database": "PubMed", "id": "11710529", "url": "https://pubmed.ncbi.nlm.nih.gov/11710529" }, { "database": "PubMed", "id": "7536927", "url": "https://pubmed.ncbi.nlm.nih.gov/7536927" }, { "database": "PubMed", "id": "7680644", "url": "https://pubmed.ncbi.nlm.nih.gov/7680644" }, { "database": "PubMed", "id": "7683666", "url": "https://pubmed.ncbi.nlm.nih.gov/7683666" }, { "database": "PubMed", "id": "7692233", "url": "https://pubmed.ncbi.nlm.nih.gov/7692233" }, { "database": "PubMed", "id": "7876130", "url": "https://pubmed.ncbi.nlm.nih.gov/7876130" }, { "database": "PubMed", "id": "9153411", "url": "https://pubmed.ncbi.nlm.nih.gov/9153411" }, { "database": "PubMed", "id": "8382774", "url": "https://pubmed.ncbi.nlm.nih.gov/8382774" }, { "database": "PubMed", "id": "8564419", "url": "https://pubmed.ncbi.nlm.nih.gov/8564419" }, { "database": "PubMed", "id": "8670861", "url": "https://pubmed.ncbi.nlm.nih.gov/8670861" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "17403678", "url": "https://pubmed.ncbi.nlm.nih.gov/17403678" }, { "database": "PubMed", "id": "17961557", "url": "https://pubmed.ncbi.nlm.nih.gov/17961557" }, { "database": "PubMed", "id": "18567737", "url": "https://pubmed.ncbi.nlm.nih.gov/18567737" }, { "database": "PubMed", "id": "2170111", "url": "https://pubmed.ncbi.nlm.nih.gov/2170111" }, { "database": "PubMed", "id": "24648957", "url": "https://pubmed.ncbi.nlm.nih.gov/24648957" }, { "database": "PubMed", "id": "28487538", "url": "https://pubmed.ncbi.nlm.nih.gov/28487538" }, { "database": "PubMed", "id": "33093618", "url": "https://pubmed.ncbi.nlm.nih.gov/33093618" }, { "database": "PubMed", "id": "33509954", "url": "https://pubmed.ncbi.nlm.nih.gov/33509954" }, { "database": "PubMed", "id": "14966296", "url": "https://pubmed.ncbi.nlm.nih.gov/14966296" }, { "database": "PubMed", "id": "1709159", "url": "https://pubmed.ncbi.nlm.nih.gov/1709159" }, { "database": "PubMed", "id": "2550144", "url": "https://pubmed.ncbi.nlm.nih.gov/2550144" } ], "site_lbl": "Tyr751", "uniprot_canonical_ac": "P09619-1" } ], "record_id": "pubmed.7692233", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation.", "journal": "Molecular and cellular biology", "date": "1994", "authors": "Arvidsson AK, Rupp E, Nanberg E, Downward J, Ronnstrand L, Wennstrom S, Schlessinger J, Heldin CH, Claesson-Welsh L", "reference": { "type": "PubMed", "id": "7935391", "url": "https://pubmed.ncbi.nlm.nih.gov/7935391" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 716, "end_pos": 716, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "7935391", "url": "https://pubmed.ncbi.nlm.nih.gov/7935391" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "15902258", "url": "https://pubmed.ncbi.nlm.nih.gov/15902258" } ], "site_lbl": "Tyr716", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 716, "end_pos": 716, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "7935391", "url": "https://pubmed.ncbi.nlm.nih.gov/7935391" }, { "database": "PubMed", "id": "8940081", "url": "https://pubmed.ncbi.nlm.nih.gov/8940081" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "16288304", "url": "https://pubmed.ncbi.nlm.nih.gov/16288304" }, { "database": "PubMed", "id": "18567737", "url": "https://pubmed.ncbi.nlm.nih.gov/18567737" }, { "database": "PubMed", "id": "26631574", "url": "https://pubmed.ncbi.nlm.nih.gov/26631574" } ], "site_lbl": "Tyr716", "uniprot_canonical_ac": "P09619-1" } ], "record_id": "pubmed.7935391", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Platelet-derived growth factor receptor mediates activation of ras through different signaling pathways in different cell types.", "journal": "Molecular and cellular biology", "date": "1993", "authors": "Satoh T, Fantl WJ, Escobedo JA, Williams LT, Kaziro Y", "reference": { "type": "PubMed", "id": "8388543", "url": "https://pubmed.ncbi.nlm.nih.gov/8388543" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8388543", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation sites at the C-terminus of the platelet-derived growth factor receptor bind phospholipase C gamma 1.", "journal": "Molecular biology of the cell", "date": "1993", "authors": "Kashishian A, Cooper JA", "reference": { "type": "PubMed", "id": "8443409", "url": "https://pubmed.ncbi.nlm.nih.gov/8443409" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8443409", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Modulation of the SH2 binding specificity and kinase activity of Src by tyrosine phosphorylation within its SH2 domain.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Stover DR, Furet P, Lydon NB", "reference": { "type": "PubMed", "id": "8647855", "url": "https://pubmed.ncbi.nlm.nih.gov/8647855" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8647855", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Platelet-derived growth factor induces phosphorylation of multiple JAK family kinases and STAT proteins.", "journal": "Molecular and cellular biology", "date": "1996", "authors": "Vignais ML, Sadowski HB, Watling D, Rogers NC, Gilman M", "reference": { "type": "PubMed", "id": "8657151", "url": "https://pubmed.ncbi.nlm.nih.gov/8657151" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8657151", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Grb7 is a downstream signaling component of platelet-derived growth factor alpha- and beta-receptors.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Yokote K, Margolis B, Heldin CH, Claesson-Welsh L", "reference": { "type": "PubMed", "id": "8940081", "url": "https://pubmed.ncbi.nlm.nih.gov/8940081" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03160-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "Grb7", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 716, "end_pos": 716, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "7935391", "url": "https://pubmed.ncbi.nlm.nih.gov/7935391" }, { "database": "PubMed", "id": "8940081", "url": "https://pubmed.ncbi.nlm.nih.gov/8940081" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" }, { "database": "PubMed", "id": "16288304", "url": "https://pubmed.ncbi.nlm.nih.gov/16288304" }, { "database": "PubMed", "id": "18567737", "url": "https://pubmed.ncbi.nlm.nih.gov/18567737" }, { "database": "PubMed", "id": "26631574", "url": "https://pubmed.ncbi.nlm.nih.gov/26631574" } ], "site_lbl": "Tyr716", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 775, "end_pos": 775, "kinase_uniprot_canonical_ac": "P09619-1", "kinase_gene_name": "PDGFRB", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "8940081", "url": "https://pubmed.ncbi.nlm.nih.gov/8940081" }, { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "PubMed", "id": "10821867", "url": "https://pubmed.ncbi.nlm.nih.gov/10821867" } ], "site_lbl": "Tyr775", "uniprot_canonical_ac": "P09619-1" }, { "start_pos": 775, "end_pos": 775, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P09619", "url": "https://www.uniprot.org/uniprotkb/P09619" }, { "database": "IntAct", "id": "P09619", "url": "https://www.ebi.ac.uk/intact/interactors/id:P09619*" }, { "database": "iPTMnet", "id": "P09619", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P09619" }, { "database": "PubMed", "id": "8940081", "url": "https://pubmed.ncbi.nlm.nih.gov/8940081" }, { "database": "PRO", "id": "P09619", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P09619" } ], "site_lbl": "Tyr775", "uniprot_canonical_ac": "P09619-1" } ], "record_id": "pubmed.8940081", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 28 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Isolation of angiopoietin-1, a ligand for the TIE2 receptor, by secretion-trap expression cloning.", "journal": "Cell", "date": "1996", "authors": "Davis S, Aldrich TH, Jones PF, Acheson A, Compton DL, Jain V, Ryan TE, Bruno J, Radziejewski C, Maisonpierre PC, Yancopoulos GD", "reference": { "type": "PubMed", "id": "8980223", "url": "https://pubmed.ncbi.nlm.nih.gov/8980223" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O08538-1", "protein_name": "Angiopoietin-1", "gene_name": "Angpt1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8980223", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Coexpression of Grb7 with epidermal growth factor receptor or Her2/erbB2 in human advanced esophageal carcinoma.", "journal": "Cancer Res.", "date": "1997", "authors": "Tanaka S, Mori M, Akiyoshi T, Tanaka Y, Mafune K, Wands JR, Sugimachi K", "reference": { "type": "PubMed", "id": "8988034", "url": "https://pubmed.ncbi.nlm.nih.gov/8988034" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8988034", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1997", "authors": "Kishi T, Sasaki H, Akiyama N, Ishizuka T, Sakamoto H, Aizawa S, Sugimura T, Terada M", "reference": { "type": "PubMed", "id": "9125150", "url": "https://pubmed.ncbi.nlm.nih.gov/9125150" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9125150", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Activation of Stat5 by platelet-derived growth factor (PDGF) is dependent on phosphorylation sites in PDGF beta-receptor juxtamembrane and kinase insert domains.", "journal": "Oncogene", "date": "1998", "authors": "Valgeirsdottir S, Paukku K, Silvennoinen O, Heldin CH, Claesson-Welsh L", "reference": { "type": "PubMed", "id": "9484840", "url": "https://pubmed.ncbi.nlm.nih.gov/9484840" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9484840", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A role for Src in signal relay by the platelet-derived growth factor alpha receptor.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Gelderloos JA, Rosenkranz S, Bazenet C, Kazlauskas A", "reference": { "type": "PubMed", "id": "9488729", "url": "https://pubmed.ncbi.nlm.nih.gov/9488729" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9488729", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Analysis of Grb7 recruitment by heregulin-activated erbB receptors reveals a novel target selectivity for erbB3.", "journal": "J. Biol. Chem.", "date": "1998", "authors": "Fiddes RJ, Campbell DH, Janes PW, Sivertsen SP, Sasaki H, Wallasch C, Daly RJ", "reference": { "type": "PubMed", "id": "9516479", "url": "https://pubmed.ncbi.nlm.nih.gov/9516479" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02297-1", "protein_name": "Pro-neuregulin-1, membrane-bound isoform", "gene_name": "NRG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14511-1", "protein_name": "Pro-neuregulin-2, membrane-bound isoform", "gene_name": "NRG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15303-1", "protein_name": "Receptor tyrosine-protein kinase erbB-4", "gene_name": "ERBB4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21860-1", "protein_name": "Receptor tyrosine-protein kinase erbB-3", "gene_name": "ERBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04626-1", "protein_name": "Receptor tyrosine-protein kinase erbB-2", "gene_name": "ERBB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1199, "end_pos": 1199, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21860", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21860" }, { "database": "PubMed", "id": "16729043", "url": "https://pubmed.ncbi.nlm.nih.gov/16729043" }, { "database": "PubMed", "id": "9516479", "url": "https://pubmed.ncbi.nlm.nih.gov/9516479" }, { "database": "IntAct", "id": "P21860", "url": "https://www.ebi.ac.uk/intact/interactors/id:P21860*" } ], "site_lbl": "Tyr1199", "uniprot_canonical_ac": "P21860-1" }, { "start_pos": 1262, "end_pos": 1262, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P21860", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P21860" }, { "database": "PubMed", "id": "16729043", "url": "https://pubmed.ncbi.nlm.nih.gov/16729043" }, { "database": "PubMed", "id": "9516479", "url": "https://pubmed.ncbi.nlm.nih.gov/9516479" }, { "database": "IntAct", "id": "P21860", "url": "https://www.ebi.ac.uk/intact/interactors/id:P21860*" }, { "database": "PubMed", "id": "16273093", "url": "https://pubmed.ncbi.nlm.nih.gov/16273093" } ], "site_lbl": "Tyr1262", "uniprot_canonical_ac": "P21860-1" } ], "record_id": "pubmed.9516479", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of Tyr-762 in the platelet-derived growth factor alpha-receptor as the binding site for Crk proteins.", "journal": "Oncogene", "date": "1998", "authors": "Yokote K, Hellman U, Ekman S, Saito Y, Ronnstrand L, Saito Y, Heldin CH, Mori S", "reference": { "type": "PubMed", "id": "9546424", "url": "https://pubmed.ncbi.nlm.nih.gov/9546424" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 762, "end_pos": 762, "kinase_uniprot_canonical_ac": "P16234-1", "kinase_gene_name": "PDGFRA", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P16234", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16234" }, { "database": "PubMed", "id": "9546424", "url": "https://pubmed.ncbi.nlm.nih.gov/9546424" }, { "database": "UniProtKB", "id": "P16234", "url": "https://www.uniprot.org/uniprotkb/P16234" }, { "database": "PubMed", "id": "10733900", "url": "https://pubmed.ncbi.nlm.nih.gov/10733900" } ], "site_lbl": "Tyr762", "uniprot_canonical_ac": "P16234-1" }, { "start_pos": 762, "end_pos": 762, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "P16234", "url": "https://www.uniprot.org/uniprotkb/P16234" }, { "database": "IntAct", "id": "P16234", "url": "https://www.ebi.ac.uk/intact/interactors/id:P16234*" }, { "database": "iPTMnet", "id": "P16234", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P16234" }, { "database": "PubMed", "id": "10733900", "url": "https://pubmed.ncbi.nlm.nih.gov/10733900" }, { "database": "PubMed", "id": "9546424", "url": "https://pubmed.ncbi.nlm.nih.gov/9546424" }, { "database": "PRO", "id": "P16234", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P16234" } ], "site_lbl": "Tyr762", "uniprot_canonical_ac": "P16234-1" } ], "record_id": "pubmed.9546424", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Kontos CD, Stauffer TP, Yang WP, York JD, Huang L, Blanar MA, Meyer T, Peters KG", "reference": { "type": "PubMed", "id": "9632797", "url": "https://pubmed.ncbi.nlm.nih.gov/9632797" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02858-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "Tek", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 1102, "end_pos": 1102, "kinase_uniprot_canonical_ac": "Q02763-1", "kinase_gene_name": "TEK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q02763", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02763" }, { "database": "PubMed", "id": "10521483", "url": "https://pubmed.ncbi.nlm.nih.gov/10521483" }, { "database": "PubMed", "id": "9632797", "url": "https://pubmed.ncbi.nlm.nih.gov/9632797" }, { "database": "PubMed", "id": "20973951", "url": "https://pubmed.ncbi.nlm.nih.gov/20973951" }, { "database": "UniProtKB", "id": "Q02763", "url": "https://www.uniprot.org/uniprotkb/Q02763" }, { "database": "PubMed", "id": "14665640", "url": "https://pubmed.ncbi.nlm.nih.gov/14665640" } ], "site_lbl": "Tyr1102", "uniprot_canonical_ac": "Q02763-1" }, { "start_pos": 1100, "end_pos": 1100, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by autocatalysis", "evidence": [ { "database": "UniProtKB", "id": "Q02858", "url": "https://www.uniprot.org/uniprotkb/Q02858" }, { "database": "IntAct", "id": "Q02858", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q02858*" }, { "database": "iPTMnet", "id": "Q02858", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q02858" }, { "database": "PubMed", "id": "10521483", "url": "https://pubmed.ncbi.nlm.nih.gov/10521483" }, { "database": "PubMed", "id": "9632797", "url": "https://pubmed.ncbi.nlm.nih.gov/9632797" } ], "site_lbl": "Tyr1100", "uniprot_canonical_ac": "Q02858-1" } ], "mutagenesis": [ { "start_pos": 1100, "end_pos": 1100, "sequence_org": "Y", "sequence_mut": "F", "comment": "Reduced levels of autophosphorylation. Abolishes interaction with GRB2 and GRB7. Abolishes phosphorylation of GRB7 and PIK3R1.", "evidence": [ { "database": "UniProtKB", "id": "Q02858", "url": "https://www.uniprot.org/uniprotkb/Q02858" }, { "database": "PubMed", "id": "10521483", "url": "https://pubmed.ncbi.nlm.nih.gov/10521483" }, { "database": "PubMed", "id": "9632797", "url": "https://pubmed.ncbi.nlm.nih.gov/9632797" }, { "database": "PubMed", "id": "12665569", "url": "https://pubmed.ncbi.nlm.nih.gov/12665569" } ], "uniprot_canonical_ac": "Q02858-1" } ], "record_id": "pubmed.9632797", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel variant of human Grb7 is associated with invasive esophageal carcinoma.", "journal": "J. Clin. Invest.", "date": "1998", "authors": "Tanaka S, Mori M, Akiyoshi T, Tanaka Y, Mafune K, Wands J R, Sugimachi K", "reference": { "type": "PubMed", "id": "9710451", "url": "https://pubmed.ncbi.nlm.nih.gov/9710451" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9710451", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Signal transduction via platelet-derived growth factor receptors.", "journal": "Biochimica et biophysica acta", "date": "1998", "authors": "Heldin CH, Ostman A, Ronnstrand L", "reference": { "type": "PubMed", "id": "9739761", "url": "https://pubmed.ncbi.nlm.nih.gov/9739761" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42229-1", "protein_name": "Signal transducer and activator of transcription 5A", "gene_name": "STAT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53420-1", "protein_name": "Collagen alpha-4(IV) chain", "gene_name": "COL4A4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51692-1", "protein_name": "Signal transducer and activator of transcription 5B", "gene_name": "STAT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09958-1", "protein_name": "Furin", "gene_name": "FURIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZP0-1", "protein_name": "Platelet-derived growth factor D", "gene_name": "PDGFD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05209-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 12", "gene_name": "PTPN12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07996-1", "protein_name": "Thrombospondin-1", "gene_name": "THBS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10451-1", "protein_name": "Osteopontin", "gene_name": "SPP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12110-1", "protein_name": "Collagen alpha-2(VI) chain", "gene_name": "COL6A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20908-1", "protein_name": "Collagen alpha-1(V) chain", "gene_name": "COL5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02462-1", "protein_name": "Collagen alpha-1(IV) chain", "gene_name": "COL4A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08572-1", "protein_name": "Collagen alpha-2(IV) chain", "gene_name": "COL4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20849-1", "protein_name": "Collagen alpha-1(IX) chain", "gene_name": "COL9A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25940-1", "protein_name": "Collagen alpha-3(V) chain", "gene_name": "COL5A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01955-1", "protein_name": "Collagen alpha-3(IV) chain", "gene_name": "COL4A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16234-1", "protein_name": "Platelet-derived growth factor receptor alpha", "gene_name": "PDGFRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35442-1", "protein_name": "Thrombospondin-2", "gene_name": "THBS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35443-1", "protein_name": "Thrombospondin-4", "gene_name": "THBS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56945-1", "protein_name": "Breast cancer anti-estrogen resistance protein 1", "gene_name": "BCAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20936-1", "protein_name": "Ras GTPase-activating protein 1", "gene_name": "RASA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00747-1", "protein_name": "Plasminogen", "gene_name": "PLG", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02461-1", "protein_name": "Collagen alpha-1(III) chain", "gene_name": "COL3A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29400-1", "protein_name": "Collagen alpha-5(IV) chain", "gene_name": "COL4A5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14055-1", "protein_name": "Collagen alpha-2(IX) chain", "gene_name": "COL9A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8TX70-1", "protein_name": "Collagen alpha-5(VI) chain", "gene_name": "COL6A5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05997-1", "protein_name": "Collagen alpha-2(V) chain", "gene_name": "COL5A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NMZ7-1", "protein_name": "Collagen alpha-6(VI) chain", "gene_name": "COL6A6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12111-1", "protein_name": "Collagen alpha-3(VI) chain", "gene_name": "COL6A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12109-1", "protein_name": "Collagen alpha-1(VI) chain", "gene_name": "COL6A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02458-2", "protein_name": "Collagen alpha-1(II) chain", "gene_name": "COL2A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14050-1", "protein_name": "Collagen alpha-3(IX) chain", "gene_name": "COL9A3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09619-1", "protein_name": "Platelet-derived growth factor receptor beta", "gene_name": "PDGFRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49746-1", "protein_name": "Thrombospondin-3", "gene_name": "THBS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40763-1", "protein_name": "Signal transducer and activator of transcription 3", "gene_name": "STAT3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01127-1", "protein_name": "Platelet-derived growth factor subunit B", "gene_name": "PDGFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42226-1", "protein_name": "Signal transducer and activator of transcription 6", "gene_name": "STAT6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00750-1", "protein_name": "Tissue-type plasminogen activator", "gene_name": "PLAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19174-1", "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "gene_name": "PLCG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12931-1", "protein_name": "Proto-oncogene tyrosine-protein kinase Src", "gene_name": "SRC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16333-1", "protein_name": "SH2/SH3 adapter protein NCK1", "gene_name": "NCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43639-1", "protein_name": "Cytoplasmic protein NCK2", "gene_name": "NCK2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9739761", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 54 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Tek/Tie2 receptor signals through a novel Dok-related docking protein, Dok-R.", "journal": "Oncogene", "date": "1998", "authors": "Jones N, Dumont DJ", "reference": { "type": "PubMed", "id": "9764820", "url": "https://pubmed.ncbi.nlm.nih.gov/9764820" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14451-1", "protein_name": "Growth factor receptor-bound protein 7", "gene_name": "GRB7", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15123-1", "protein_name": "Angiopoietin-2", "gene_name": "ANGPT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15389-1", "protein_name": "Angiopoietin-1", "gene_name": "ANGPT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y264-1", "protein_name": "Angiopoietin-4", "gene_name": "ANGPT4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02763-1", "protein_name": "Angiopoietin-1 receptor", "gene_name": "TEK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14449-1", "protein_name": "Growth factor receptor-bound protein 14", "gene_name": "GRB14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60496-1", "protein_name": "Docking protein 2", "gene_name": "DOK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07889-1", "protein_name": "Son of sevenless homolog 1", "gene_name": "SOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "O70469-1", "protein_name": "Docking protein 2", "gene_name": "Dok2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29353-1", "protein_name": "SHC-transforming protein 1", "gene_name": "SHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14451", "url": "https://www.uniprot.org/uniprotkb/Q14451" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 345, "end_pos": 345, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "O60496", "url": "https://www.uniprot.org/uniprotkb/O60496" }, { "database": "iPTMnet", "id": "O60496", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O60496" }, { "database": "PubMed", "id": "11689432", "url": "https://pubmed.ncbi.nlm.nih.gov/11689432" }, { "database": "PubMed", "id": "9764820", "url": "https://pubmed.ncbi.nlm.nih.gov/9764820" }, { "database": "IntAct", "id": "O60496", "url": "https://www.ebi.ac.uk/intact/interactors/id:O60496*" }, { "database": "PubMed", "id": "10428862", "url": "https://pubmed.ncbi.nlm.nih.gov/10428862" } ], "site_lbl": "Tyr345", "uniprot_canonical_ac": "O60496-1" } ], "record_id": "pubmed.9764820", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 17 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of a type 6 protein ser/thr phosphatase regulated by interleukin-2 stimulation.", "journal": "Journal of cellular biochemistry", "date": "1999-05-01", "authors": "Filali M, Li S, Kim H W, Wadzinski B, Kamoun M", "reference": { "type": "PubMed", "id": "10227379", "url": "https://pubmed.ncbi.nlm.nih.gov/10227379" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10227379", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional conservation of the telomerase protein Est1p in humans.", "journal": "Current biology : CB", "date": "2003", "authors": "Snow BE, Erdmann N, Cruickshank J, Goldman H, Gill RM, Robinson MO, Harrington L", "reference": { "type": "PubMed", "id": "12699629", "url": "https://pubmed.ncbi.nlm.nih.gov/12699629" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86US8-1", "protein_name": "Telomerase-binding protein EST1A", "gene_name": "SMG6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPR3-1", "protein_name": "Nonsense-mediated mRNA decay factor SMG5", "gene_name": "SMG5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12699629", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1.", "journal": "Molecular and cellular biology", "date": "2004", "authors": "Armbruster BN, Linardic CM, Veldman T, Bansal NP, Downie DL, Counter CM", "reference": { "type": "PubMed", "id": "15060173", "url": "https://pubmed.ncbi.nlm.nih.gov/15060173" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15060173", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of telomerase by telomeric proteins.", "journal": "Annual review of biochemistry", "date": "2004", "authors": "Smogorzewska A, de Lange T", "reference": { "type": "PubMed", "id": "15189140", "url": "https://pubmed.ncbi.nlm.nih.gov/15189140" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15189140", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cell cycle-regulated trafficking of human telomerase to telomeres.", "journal": "Molecular biology of the cell", "date": "2006", "authors": "Tomlinson RL, Ziegler TD, Supakorndej T, Terns RM, Terns MP", "reference": { "type": "PubMed", "id": "16339074", "url": "https://pubmed.ncbi.nlm.nih.gov/16339074" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16339074", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The human Pif1 helicase, a potential Escherichia coli RecD homologue, inhibits telomerase activity.", "journal": "Nucleic acids research", "date": "2006", "authors": "Zhang DH, Zhou B, Huang Y, Xu LX, Zhou JQ", "reference": { "type": "PubMed", "id": "16522649", "url": "https://pubmed.ncbi.nlm.nih.gov/16522649" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5ZJH9-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 234, "end_pos": 234, "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of ATPase activity. Lower activity for single-stranded DNA.", "evidence": [ { "database": "UniProtKB", "id": "Q9H611", "url": "https://www.uniprot.org/uniprotkb/Q9H611" }, { "database": "PubMed", "id": "16522649", "url": "https://pubmed.ncbi.nlm.nih.gov/16522649" } ], "uniprot_canonical_ac": "Q9H611-1" } ], "record_id": "pubmed.16522649", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Protein phosphatase 6 down-regulates TAK1 kinase activation in the IL-1 signaling pathway.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Kajino T, Ren H, Iemura S, Natsume T, Stefansson B, Brautigan DL, Matsumoto K, Ninomiya-Tsuji J", "reference": { "type": "PubMed", "id": "17079228", "url": "https://pubmed.ncbi.nlm.nih.gov/17079228" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43318-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 7", "gene_name": "MAP3K7", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 187, "end_pos": 187, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by autocatalysis; alternate", "evidence": [ { "database": "UniProtKB", "id": "O43318", "url": "https://www.uniprot.org/uniprotkb/O43318" }, { "database": "PRO", "id": "O43318", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=O43318" }, { "database": "iPTMnet", "id": "O43318", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O43318" }, { "database": "PubMed", "id": "15590691", "url": "https://pubmed.ncbi.nlm.nih.gov/15590691" }, { "database": "PubMed", "id": "17079228", "url": "https://pubmed.ncbi.nlm.nih.gov/17079228" }, { "database": "PubMed", "id": "18299321", "url": "https://pubmed.ncbi.nlm.nih.gov/18299321" }, { "database": "PubMed", "id": "19112497", "url": "https://pubmed.ncbi.nlm.nih.gov/19112497" }, { "database": "PubMed", "id": "19232515", "url": "https://pubmed.ncbi.nlm.nih.gov/19232515" }, { "database": "PubMed", "id": "19284290", "url": "https://pubmed.ncbi.nlm.nih.gov/19284290" }, { "database": "PubMed", "id": "20538596", "url": "https://pubmed.ncbi.nlm.nih.gov/20538596" }, { "database": "PubMed", "id": "22590573", "url": "https://pubmed.ncbi.nlm.nih.gov/22590573" }, { "database": "PubMed", "id": "23229544", "url": "https://pubmed.ncbi.nlm.nih.gov/23229544" }, { "database": "PubMed", "id": "23472066", "url": "https://pubmed.ncbi.nlm.nih.gov/23472066" }, { "database": "PubMed", "id": "23646170", "url": "https://pubmed.ncbi.nlm.nih.gov/23646170" }, { "database": "PubMed", "id": "24736749", "url": "https://pubmed.ncbi.nlm.nih.gov/24736749" }, { "database": "PubMed", "id": "24912525", "url": "https://pubmed.ncbi.nlm.nih.gov/24912525" }, { "database": "PubMed", "id": "25849436", "url": "https://pubmed.ncbi.nlm.nih.gov/25849436" }, { "database": "PubMed", "id": "26100626", "url": "https://pubmed.ncbi.nlm.nih.gov/26100626" }, { "database": "PubMed", "id": "27486461", "url": "https://pubmed.ncbi.nlm.nih.gov/27486461" }, { "database": "PubMed", "id": "28231796", "url": "https://pubmed.ncbi.nlm.nih.gov/28231796" }, { "database": "PubMed", "id": "28507161", "url": "https://pubmed.ncbi.nlm.nih.gov/28507161" }, { "database": "PubMed", "id": "28553204", "url": "https://pubmed.ncbi.nlm.nih.gov/28553204" }, { "database": "PubMed", "id": "28714004", "url": "https://pubmed.ncbi.nlm.nih.gov/28714004" }, { "database": "PubMed", "id": "28819003", "url": "https://pubmed.ncbi.nlm.nih.gov/28819003" }, { "database": "PubMed", "id": "28906490", "url": "https://pubmed.ncbi.nlm.nih.gov/28906490" }, { "database": "PubMed", "id": "28993672", "url": "https://pubmed.ncbi.nlm.nih.gov/28993672" }, { "database": "PubMed", "id": "30168902", "url": "https://pubmed.ncbi.nlm.nih.gov/30168902" }, { "database": "PubMed", "id": "30626936", "url": "https://pubmed.ncbi.nlm.nih.gov/30626936" }, { "database": "PubMed", "id": "33052966", "url": "https://pubmed.ncbi.nlm.nih.gov/33052966" }, { "database": "PubMed", "id": "16845370", "url": "https://pubmed.ncbi.nlm.nih.gov/16845370" }, { "database": "PubMed", "id": "19675569", "url": "https://pubmed.ncbi.nlm.nih.gov/19675569" }, { "database": "PubMed", "id": "21512573", "url": "https://pubmed.ncbi.nlm.nih.gov/21512573" } ], "site_lbl": "Thr187", "uniprot_canonical_ac": "O43318-1" } ], "record_id": "pubmed.17079228", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human PIF helicase is cell cycle regulated and associates with telomerase.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2006", "authors": "Mateyak MK, Zakian VA", "reference": { "type": "PubMed", "id": "17172855", "url": "https://pubmed.ncbi.nlm.nih.gov/17172855" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17172855", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Protein composition of catalytically active human telomerase from immortal cells.", "journal": "Science (New York, N.Y.)", "date": "2007", "authors": "Cohen SB, Graham ME, Lovrecz GO, Bache N, Robinson PJ, Reddel RR", "reference": { "type": "PubMed", "id": "17395830", "url": "https://pubmed.ncbi.nlm.nih.gov/17395830" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5ZJH9-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17395830", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Protein phosphatase PP6 N terminal domain restricts G1 to S phase progression in human cancer cells.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2007", "authors": "Stefansson B, Brautigan DL", "reference": { "type": "PubMed", "id": "17568194", "url": "https://pubmed.ncbi.nlm.nih.gov/17568194" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06400-1", "protein_name": "Retinoblastoma-associated protein", "gene_name": "RB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 807, "end_pos": 807, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CDK1 and CDK3", "evidence": [ { "database": "UniProtKB", "id": "P06400", "url": "https://www.uniprot.org/uniprotkb/P06400" }, { "database": "iPTMnet", "id": "P06400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P06400" }, { "database": "PubMed", "id": "15084261", "url": "https://pubmed.ncbi.nlm.nih.gov/15084261" }, { "database": "PubMed", "id": "15741232", "url": "https://pubmed.ncbi.nlm.nih.gov/15741232" }, { "database": "PubMed", "id": "15809340", "url": "https://pubmed.ncbi.nlm.nih.gov/15809340" }, { "database": "PubMed", "id": "22094256", "url": "https://pubmed.ncbi.nlm.nih.gov/22094256" }, { "database": "PubMed", "id": "9139732", "url": "https://pubmed.ncbi.nlm.nih.gov/9139732" }, { "database": "PubMed", "id": "15194426", "url": "https://pubmed.ncbi.nlm.nih.gov/15194426" }, { "database": "PubMed", "id": "15941859", "url": "https://pubmed.ncbi.nlm.nih.gov/15941859" }, { "database": "PubMed", "id": "16236452", "url": "https://pubmed.ncbi.nlm.nih.gov/16236452" }, { "database": "PubMed", "id": "1756735", "url": "https://pubmed.ncbi.nlm.nih.gov/1756735" }, { "database": "PubMed", "id": "17568194", "url": "https://pubmed.ncbi.nlm.nih.gov/17568194" }, { "database": "PubMed", "id": "18190706", "url": "https://pubmed.ncbi.nlm.nih.gov/18190706" }, { "database": "PubMed", "id": "18383818", "url": "https://pubmed.ncbi.nlm.nih.gov/18383818" }, { "database": "PubMed", "id": "18784806", "url": "https://pubmed.ncbi.nlm.nih.gov/18784806" }, { "database": "PubMed", "id": "18938028", "url": "https://pubmed.ncbi.nlm.nih.gov/18938028" }, { "database": "PubMed", "id": "20703084", "url": "https://pubmed.ncbi.nlm.nih.gov/20703084" }, { "database": "PubMed", "id": "21115810", "url": "https://pubmed.ncbi.nlm.nih.gov/21115810" }, { "database": "PubMed", "id": "22787429", "url": "https://pubmed.ncbi.nlm.nih.gov/22787429" }, { "database": "PubMed", "id": "24274149", "url": "https://pubmed.ncbi.nlm.nih.gov/24274149" }, { "database": "PubMed", "id": "24401087", "url": "https://pubmed.ncbi.nlm.nih.gov/24401087" }, { "database": "PubMed", "id": "24463355", "url": "https://pubmed.ncbi.nlm.nih.gov/24463355" }, { "database": "PubMed", "id": "25009665", "url": "https://pubmed.ncbi.nlm.nih.gov/25009665" }, { "database": "PubMed", "id": "25522274", "url": "https://pubmed.ncbi.nlm.nih.gov/25522274" }, { "database": "PubMed", "id": "25695870", "url": "https://pubmed.ncbi.nlm.nih.gov/25695870" }, { "database": "PubMed", "id": "26121043", "url": "https://pubmed.ncbi.nlm.nih.gov/26121043" }, { "database": "PubMed", "id": "27527160", "url": "https://pubmed.ncbi.nlm.nih.gov/27527160" }, { "database": "PubMed", "id": "28169375", "url": "https://pubmed.ncbi.nlm.nih.gov/28169375" }, { "database": "PubMed", "id": "28176922", "url": "https://pubmed.ncbi.nlm.nih.gov/28176922" }, { "database": "PubMed", "id": "28734226", "url": "https://pubmed.ncbi.nlm.nih.gov/28734226" }, { "database": "PubMed", "id": "29088742", "url": "https://pubmed.ncbi.nlm.nih.gov/29088742" }, { "database": "PubMed", "id": "31042625", "url": "https://pubmed.ncbi.nlm.nih.gov/31042625" }, { "database": "PubMed", "id": "33324635", "url": "https://pubmed.ncbi.nlm.nih.gov/33324635" }, { "database": "PubMed", "id": "33556114", "url": "https://pubmed.ncbi.nlm.nih.gov/33556114" }, { "database": "PubMed", "id": "18669648", "url": "https://pubmed.ncbi.nlm.nih.gov/18669648" }, { "database": "PubMed", "id": "19690332", "url": "https://pubmed.ncbi.nlm.nih.gov/19690332" }, { "database": "PubMed", "id": "23186163", "url": "https://pubmed.ncbi.nlm.nih.gov/23186163" } ], "site_lbl": "Ser807", "uniprot_canonical_ac": "P06400-1" }, { "start_pos": 811, "end_pos": 811, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by CDK1 and CDK3", "evidence": [ { "database": "UniProtKB", "id": "P06400", "url": "https://www.uniprot.org/uniprotkb/P06400" }, { "database": "iPTMnet", "id": "P06400", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P06400" }, { "database": "PubMed", "id": "15084261", "url": "https://pubmed.ncbi.nlm.nih.gov/15084261" }, { "database": "PubMed", "id": "15741232", "url": "https://pubmed.ncbi.nlm.nih.gov/15741232" }, { "database": "PubMed", "id": "22094256", "url": "https://pubmed.ncbi.nlm.nih.gov/22094256" }, { "database": "PubMed", "id": "9139732", "url": "https://pubmed.ncbi.nlm.nih.gov/9139732" }, { "database": "PubMed", "id": "15194426", "url": "https://pubmed.ncbi.nlm.nih.gov/15194426" }, { "database": "PubMed", "id": "15941859", "url": "https://pubmed.ncbi.nlm.nih.gov/15941859" }, { "database": "PubMed", "id": "16236452", "url": "https://pubmed.ncbi.nlm.nih.gov/16236452" }, { "database": "PubMed", "id": "1756735", "url": "https://pubmed.ncbi.nlm.nih.gov/1756735" }, { "database": "PubMed", "id": "17568194", "url": "https://pubmed.ncbi.nlm.nih.gov/17568194" }, { "database": "PubMed", "id": "18190706", "url": "https://pubmed.ncbi.nlm.nih.gov/18190706" }, { "database": "PubMed", "id": "18383818", "url": "https://pubmed.ncbi.nlm.nih.gov/18383818" }, { "database": "PubMed", "id": "18784806", "url": "https://pubmed.ncbi.nlm.nih.gov/18784806" }, { "database": "PubMed", "id": "18938028", "url": "https://pubmed.ncbi.nlm.nih.gov/18938028" }, { "database": "PubMed", "id": "20703084", "url": "https://pubmed.ncbi.nlm.nih.gov/20703084" }, { "database": "PubMed", "id": "21115810", "url": "https://pubmed.ncbi.nlm.nih.gov/21115810" }, { "database": "PubMed", "id": "22787429", "url": "https://pubmed.ncbi.nlm.nih.gov/22787429" }, { "database": "PubMed", "id": "24401087", "url": "https://pubmed.ncbi.nlm.nih.gov/24401087" }, { "database": "PubMed", "id": "24463355", "url": "https://pubmed.ncbi.nlm.nih.gov/24463355" }, { "database": "PubMed", "id": "25522274", "url": "https://pubmed.ncbi.nlm.nih.gov/25522274" }, { "database": "PubMed", "id": "25695870", "url": "https://pubmed.ncbi.nlm.nih.gov/25695870" }, { "database": "PubMed", "id": "26121043", "url": "https://pubmed.ncbi.nlm.nih.gov/26121043" }, { "database": "PubMed", "id": "27527160", "url": "https://pubmed.ncbi.nlm.nih.gov/27527160" }, { "database": "PubMed", "id": "28169375", "url": "https://pubmed.ncbi.nlm.nih.gov/28169375" }, { "database": "PubMed", "id": "28176922", "url": "https://pubmed.ncbi.nlm.nih.gov/28176922" }, { "database": "PubMed", "id": "28734226", "url": "https://pubmed.ncbi.nlm.nih.gov/28734226" }, { "database": "PubMed", "id": "29088742", "url": "https://pubmed.ncbi.nlm.nih.gov/29088742" }, { "database": "PubMed", "id": "31042625", "url": "https://pubmed.ncbi.nlm.nih.gov/31042625" }, { "database": "PubMed", "id": "33324635", "url": "https://pubmed.ncbi.nlm.nih.gov/33324635" }, { "database": "PubMed", "id": "33556114", "url": "https://pubmed.ncbi.nlm.nih.gov/33556114" }, { "database": "PubMed", "id": "18669648", "url": "https://pubmed.ncbi.nlm.nih.gov/18669648" }, { "database": "PubMed", "id": "23186163", "url": "https://pubmed.ncbi.nlm.nih.gov/23186163" } ], "site_lbl": "Ser811", "uniprot_canonical_ac": "P06400-1" } ], "record_id": "pubmed.17568194", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly.", "journal": "Cell", "date": "2008", "authors": "Venteicher AS, Meng Z, Mason PJ, Veenstra TD, Artandi SE", "reference": { "type": "PubMed", "id": "18358808", "url": "https://pubmed.ncbi.nlm.nih.gov/18358808" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5ZJH9-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18358808", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mutations in the telomerase component NHP2 cause the premature ageing syndrome dyskeratosis congenita.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2008", "authors": "Vulliamy T, Beswick R, Kirwan M, Marrone A, Digweed M, Walne A, Dokal I", "reference": { "type": "PubMed", "id": "18523010", "url": "https://pubmed.ncbi.nlm.nih.gov/18523010" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5ZJH9-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18523010", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis.", "journal": "Science (New York, N.Y.)", "date": "2009", "authors": "Venteicher AS, Abreu EB, Meng Z, McCann KE, Terns RM, Veenstra TD, Terns MP, Artandi SE", "reference": { "type": "PubMed", "id": "19179534", "url": "https://pubmed.ncbi.nlm.nih.gov/19179534" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86US8-1", "protein_name": "Telomerase-binding protein EST1A", "gene_name": "SMG6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99973-1", "protein_name": "Telomerase protein component 1", "gene_name": "TEP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19179534", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SHQ1 is required prior to NAF1 for assembly of H/ACA small nucleolar and telomerase RNPs.", "journal": "RNA (New York, N.Y.)", "date": "2009", "authors": "Grozdanov PN, Roy S, Kittur N, Meier UT", "reference": { "type": "PubMed", "id": "19383767", "url": "https://pubmed.ncbi.nlm.nih.gov/19383767" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19383767", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Pathogenic NAP57 mutations decrease ribonucleoprotein assembly in dyskeratosis congenita.", "journal": "Human molecular genetics", "date": "2009", "authors": "Grozdanov PN, Fernandez-Fuentes N, Fiser A, Meier UT", "reference": { "type": "PubMed", "id": "19734544", "url": "https://pubmed.ncbi.nlm.nih.gov/19734544" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 353, "end_pos": 353, "sequence_org": "A", "sequence_mut": "R", "comment": "Increases interaction with SHQ1.", "evidence": [ { "database": "UniProtKB", "id": "O60832", "url": "https://www.uniprot.org/uniprotkb/O60832" }, { "database": "PubMed", "id": "19734544", "url": "https://pubmed.ncbi.nlm.nih.gov/19734544" } ], "uniprot_canonical_ac": "O60832-1" } ], "record_id": "pubmed.19734544", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TIN2-tethered TPP1 recruits human telomerase to telomeres in vivo.", "journal": "Molecular and cellular biology", "date": "2010", "authors": "Abreu E, Aritonovska E, Reichenbach P, Cristofari G, Culp B, Terns RM, Lingner J, Terns MP", "reference": { "type": "PubMed", "id": "20404094", "url": "https://pubmed.ncbi.nlm.nih.gov/20404094" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20404094", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human Pif1 helicase is a G-quadruplex DNA-binding protein with G-quadruplex DNA-unwinding activity.", "journal": "The Biochemical journal", "date": "2010", "authors": "Sanders CM", "reference": { "type": "PubMed", "id": "20524933", "url": "https://pubmed.ncbi.nlm.nih.gov/20524933" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20524933", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RTEL1 dismantles T loops and counteracts telomeric G4-DNA to maintain telomere integrity.", "journal": "Cell", "date": "2012", "authors": "Vannier JB, Pavicic-Kaltenbrunner V, Petalcorin MI, Ding H, Boulton SJ", "reference": { "type": "PubMed", "id": "22579284", "url": "https://pubmed.ncbi.nlm.nih.gov/22579284" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0VGM9-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "Rtel1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22579284", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The TEL patch of telomere protein TPP1 mediates telomerase recruitment and processivity.", "journal": "Nature", "date": "2012", "authors": "Nandakumar J, Bell CF, Weidenfeld I, Zaug AJ, Leinwand LA, Cech TR", "reference": { "type": "PubMed", "id": "23103865", "url": "https://pubmed.ncbi.nlm.nih.gov/23103865" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23103865", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Pif1 family helicases suppress genome instability at G-quadruplex motifs.", "journal": "Nature", "date": "2013", "authors": "Paeschke K, Bochman ML, Garcia PD, Cejka P, Friedman KL, Kowalczykowski SC, Zakian VA", "reference": { "type": "PubMed", "id": "23657261", "url": "https://pubmed.ncbi.nlm.nih.gov/23657261" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38766-1", "protein_name": "ATP-dependent DNA helicase RRM3", "gene_name": "RRM3", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07271-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23657261", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Genetic and molecular identification of three human TPP1 functions in telomerase action: recruitment, activation, and homeostasis set point regulation.", "journal": "Genes & development", "date": "2014", "authors": "Sexton AN, Regalado SG, Lai CS, Cost GJ, O'Neil CM, Urnov FD, Gregory PD, Jaenisch R, Collins K, Hockemeyer D", "reference": { "type": "PubMed", "id": "25128433", "url": "https://pubmed.ncbi.nlm.nih.gov/25128433" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25128433", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of human TERT elements necessary for telomerase recruitment to telomeres.", "journal": "eLife", "date": "2014", "authors": "Schmidt JC, Dalby AB, Cech TR", "reference": { "type": "PubMed", "id": "25271372", "url": "https://pubmed.ncbi.nlm.nih.gov/25271372" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25271372", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TRF2 recruits RTEL1 to telomeres in S phase to promote t-loop unwinding.", "journal": "Molecular cell", "date": "2015", "authors": "Sarek G, Vannier JB, Panier S, Petrini JHJ, Boulton SJ", "reference": { "type": "PubMed", "id": "25620558", "url": "https://pubmed.ncbi.nlm.nih.gov/25620558" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25620558", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Aurora A kinase regulates proper spindle positioning in C. elegans and in human cells.", "journal": "Journal of cell science", "date": "2016-08-01", "authors": "Kotak Sachin, Afshar Katayon, Busso Coralie, G\u00f6nczy Pierre", "reference": { "type": "PubMed", "id": "27335426", "url": "https://pubmed.ncbi.nlm.nih.gov/27335426" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14965-1", "protein_name": "Aurora kinase A", "gene_name": "AURKA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27335426", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Assembly of the WHIP-TRIM14-PPP6C Mitochondrial Complex Promotes RIG-I-Mediated Antiviral Signaling.", "journal": "Molecular cell", "date": "2017", "authors": "Tan P, He L, Cui J, Qian C, Cao X, Lin M, Zhu Q, Li Y, Xing C, Yu X, Wang HY, Wang RF", "reference": { "type": "PubMed", "id": "29053956", "url": "https://pubmed.ncbi.nlm.nih.gov/29053956" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96S55-1", "protein_name": "ATPase WRNIP1", "gene_name": "WRNIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14142-1", "protein_name": "Tripartite motif-containing protein 14", "gene_name": "TRIM14", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.29053956", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Inherited SHQ1 mutations impair interaction with NAP57/dyskerin, a major target in dyskeratosis congenita.", "journal": "Molecular genetics & genomic medicine", "date": "2017", "authors": "Bizarro J, Meier UT", "reference": { "type": "PubMed", "id": "29178645", "url": "https://pubmed.ncbi.nlm.nih.gov/29178645" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.29178645", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cryo-EM structure of substrate-bound human telomerase holoenzyme.", "journal": "Nature", "date": "2018", "authors": "Nguyen THD, Tam J, Wu RA, Greber BJ, Toso D, Nogales E, Collins K", "reference": { "type": "PubMed", "id": "29695869", "url": "https://pubmed.ncbi.nlm.nih.gov/29695869" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.29695869", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle.", "journal": "Nature", "date": "2019", "authors": "Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, Zheng XF, Flynn HR, Snijders AP, Chowdhury D, Cesare AJ, Boulton SJ", "reference": { "type": "PubMed", "id": "31723267", "url": "https://pubmed.ncbi.nlm.nih.gov/31723267" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5H9R7-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "gene_name": "PPP6R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20248-1", "protein_name": "Cyclin-A2", "gene_name": "CCNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX24-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 2", "gene_name": "NHP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPE3-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 3", "gene_name": "NOP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ71-1", "protein_name": "Regulator of telomere elongation helicase 1", "gene_name": "RTEL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15554-3", "protein_name": "Telomeric repeat-binding factor 2", "gene_name": "TERF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60832-1", "protein_name": "H/ACA ribonucleoprotein complex subunit DKC1", "gene_name": "DKC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78396-1", "protein_name": "Cyclin-A1", "gene_name": "CCNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14746-1", "protein_name": "Telomerase reverse transcriptase", "gene_name": "TERT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y265-1", "protein_name": "RuvB-like 1", "gene_name": "RUVBL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY12-1", "protein_name": "H/ACA ribonucleoprotein complex subunit 1", "gene_name": "GAR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYB0-1", "protein_name": "Telomeric repeat-binding factor 2-interacting protein 1", "gene_name": "TERF2IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15084-3", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A", "gene_name": "ANKRD28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUR4-1", "protein_name": "Telomerase Cajal body protein 1", "gene_name": "WRAP53", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H611-1", "protein_name": "ATP-dependent DNA helicase PIF1", "gene_name": "PIF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24941-1", "protein_name": "Cyclin-dependent kinase 2", "gene_name": "CDK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y230-1", "protein_name": "RuvB-like 2", "gene_name": "RUVBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PI26-1", "protein_name": "Protein SHQ1 homolog", "gene_name": "SHQ1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54274-1", "protein_name": "Telomeric repeat-binding factor 1", "gene_name": "TERF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AP0-3", "protein_name": "Adrenocortical dysplasia protein homolog", "gene_name": "ACD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BSI4-1", "protein_name": "TERF1-interacting nuclear factor 2", "gene_name": "TINF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NUX5-1", "protein_name": "Protection of telomeres protein 1", "gene_name": "POT1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.31723267", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PPP6C Negatively Regulates STING-Dependent Innate Immune Responses.", "journal": "mBio", "date": "2020", "authors": "Ni G, Ma Z, Wong JP, Zhang Z, Cousins E, Major MB, Damania B", "reference": { "type": "PubMed", "id": "32753499", "url": "https://pubmed.ncbi.nlm.nih.gov/32753499" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 366, "end_pos": 366, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by TBK1", "evidence": [ { "database": "UniProtKB", "id": "Q86WV6", "url": "https://www.uniprot.org/uniprotkb/Q86WV6" }, { "database": "iPTMnet", "id": "Q86WV6", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q86WV6" }, { "database": "PubMed", "id": "29491158", "url": "https://pubmed.ncbi.nlm.nih.gov/29491158" }, { "database": "PubMed", "id": "30321235", "url": "https://pubmed.ncbi.nlm.nih.gov/30321235" }, { "database": "PubMed", "id": "32582856", "url": "https://pubmed.ncbi.nlm.nih.gov/32582856" }, { "database": "PubMed", "id": "32690950", "url": "https://pubmed.ncbi.nlm.nih.gov/32690950" }, { "database": "PubMed", "id": "27302953", "url": "https://pubmed.ncbi.nlm.nih.gov/27302953" }, { "database": "PubMed", "id": "32753499", "url": "https://pubmed.ncbi.nlm.nih.gov/32753499" }, { "database": "PubMed", "id": "25636800", "url": "https://pubmed.ncbi.nlm.nih.gov/25636800" } ], "site_lbl": "Ser366", "uniprot_canonical_ac": "Q86WV6-1" } ], "record_id": "pubmed.32753499", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP(L) to promote TNFalpha-mediated cell death.", "journal": "Cell death & disease", "date": "2022", "authors": "Wu G, Li D, Liang W, Sun W, Xie X, Tong Y, Shan B, Zhang M, Lu X, Yuan J, Li Y", "reference": { "type": "PubMed", "id": "36071040", "url": "https://pubmed.ncbi.nlm.nih.gov/36071040" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36071040", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "M6A-induced transcription factor IRF5 contributes to the progression of cervical cancer by upregulating PPP6C.", "journal": "Clinical and experimental pharmacology & physiology", "date": "2024-07", "authors": "Hou Peng-Xiao, Fan Qian, Zhang Qin, Liu Jia-Jia, Wu Qian", "reference": { "type": "PubMed", "id": "38745265", "url": "https://pubmed.ncbi.nlm.nih.gov/38745265" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13568-1", "protein_name": "Interferon regulatory factor 5", "gene_name": "IRF5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38745265", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The protein phosphatase PP6 promotes RIPK1-dependent PANoptosis.", "journal": "BMC biology", "date": "2024-05-29", "authors": "Bynigeri Ratnakar R, Malireddi R K Subbarao, Mall Raghvendra, Connelly Jon P, Pruett-Miller Shondra M, Kanneganti Thirumala-Devi", "reference": { "type": "PubMed", "id": "38807188", "url": "https://pubmed.ncbi.nlm.nih.gov/38807188" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38807188", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The novel human protein serine/threonine phosphatase 6 is a functional homologue of budding yeast Sit4p and fission yeast ppe1, which are involved in cell cycle regulation.", "journal": "J. Cell Sci.", "date": "1996", "authors": "Bastians H, Ponstingl H", "reference": { "type": "PubMed", "id": "9013334", "url": "https://pubmed.ncbi.nlm.nih.gov/9013334" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9013334", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Alpha 4 associates with protein phosphatases 2A, 4, and 6.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1998", "authors": "Chen J, Peterson R T, Schreiber S L", "reference": { "type": "PubMed", "id": "9647778", "url": "https://pubmed.ncbi.nlm.nih.gov/9647778" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O00743-1", "protein_name": "Serine/threonine-protein phosphatase 6 catalytic subunit", "gene_name": "PPP6C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78318-1", "protein_name": "Immunoglobulin-binding protein 1", "gene_name": "IGBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O00743", "url": "https://www.uniprot.org/uniprotkb/O00743" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9647778", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Crystal structure of a human peptidyl-tRNA hydrolase reveals a new fold and suggests basis for a bifunctional activity.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "De Pereda JM, Waas WF, Jan Y, Ruoslahti E, Schimmel P, Pascual J", "reference": { "type": "PubMed", "id": "14660562", "url": "https://pubmed.ncbi.nlm.nih.gov/14660562" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y3E5-1", "protein_name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "gene_name": "PTRH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y79-1", "protein_name": "Peptidyl-tRNA hydrolase", "gene_name": "PTRH1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y3E5", "url": "https://www.uniprot.org/uniprotkb/Q9Y3E5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14660562", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors.", "journal": "Cell", "date": "2004", "authors": "Jan Y, Matter M, Pai JT, Chen YL, Pilch J, Komatsu M, Ong E, Fukuda M, Ruoslahti E", "reference": { "type": "PubMed", "id": "15006356", "url": "https://pubmed.ncbi.nlm.nih.gov/15006356" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y3E5-1", "protein_name": "Peptidyl-tRNA hydrolase 2, mitochondrial", "gene_name": "PTRH2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y3E5", "url": "https://www.uniprot.org/uniprotkb/Q9Y3E5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15006356", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] } ]