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manifested by the interplay of novel MAL antisense long noncoding RNA AC103563.8, E7 oncoprotein and EZH2.", "journal": "Clinical epigenetics", "date": "2024-03-10", "authors": "Sinha Abarna, Ghosh Abhisikta, Ghosh Arnab, Mathai Sonia, Bhaumik Jaydip, Mukhopadhyay Asima, Maitra Arindam, Biswas Nidhan K, Sengupta Sharmila", "reference": { "type": "PubMed", "id": "38461243", "url": "https://pubmed.ncbi.nlm.nih.gov/38461243" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P21145-1", "protein_name": "Myelin and lymphocyte protein", "gene_name": "MAL", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P21145", "url": "https://www.uniprot.org/uniprotkb/P21145" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38461243", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], 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Yongmei, Yang Dan, Shang NiYa, Tian Yamin, Jia Jun", "reference": { "type": "PubMed", "id": "38678596", "url": "https://pubmed.ncbi.nlm.nih.gov/38678596" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P21145-1", "protein_name": "Myelin and lymphocyte protein", "gene_name": "MAL", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P21145", "url": "https://www.uniprot.org/uniprotkb/P21145" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.38678596", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Alternative splicing of human T-cell-specific MAL mRNA and its correlation with the exon/intron organization of the gene.", "journal": "Genomics", "date": "1994", "authors": "Ranca\u00f1o C, Rubio T, Alonso M A", "reference": { "type": "PubMed", "id": "8088843", "url": "https://pubmed.ncbi.nlm.nih.gov/8088843" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P21145-1", "protein_name": "Myelin and lymphocyte protein", "gene_name": "MAL", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", 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of MAL, a human T-cell-specific proteolipid protein.", "journal": "J. Biol. Chem.", "date": "1994", "authors": "Rancano C, Rubio T, Correas I, Alonso MA", "reference": { "type": "PubMed", "id": "8132541", "url": "https://pubmed.ncbi.nlm.nih.gov/8132541" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P21145-1", "protein_name": "Myelin and lymphocyte protein", "gene_name": "MAL", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P21145", "url": "https://www.uniprot.org/uniprotkb/P21145" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8132541", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"authors": "Gao Q, Wang P, Qiu H, Qiu B, Yi W, Tu W, Lin B, Sun D, Zeng R, Huang M, Chen J, Cen J, Zhuang J", "reference": { "type": "PubMed", "id": "33743352", "url": "https://pubmed.ncbi.nlm.nih.gov/33743352" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P15173-1", "protein_name": "Myogenin", "gene_name": "MYOG", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P15173", "url": "https://www.uniprot.org/uniprotkb/P15173" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33743352", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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biochemistry", "date": "2010", "authors": "Aleksandrova A, Galkin O, Koneni R, Fontes JD", "reference": { "type": "PubMed", "id": "19777325", "url": "https://pubmed.ncbi.nlm.nih.gov/19777325" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P98168-1", "protein_name": "Zinc finger X-linked protein ZXDA", "gene_name": "ZXDA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2QGD7-1", "protein_name": "Zinc finger protein ZXDC", "gene_name": "ZXDC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P98168", "url": "https://www.uniprot.org/uniprotkb/P98168" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19777325", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CircZXDC Promotes Vascular Smooth Muscle Cell Transdifferentiation via Regulating miRNA-125a-3p/ABCC6 in Moyamoya Disease.", "journal": "Cells", "date": "2022-11-26", "authors": "Liu Yuan, Huang Yimin, Zhang Xincheng, Ma Xiaopeng, He Xuejun, Gan Chao, Zou Xin, Wang Sheng, Shu Kai, Lei Ting, Zhang Huaqiu", "reference": { "type": "PubMed", "id": "36497052", "url": "https://pubmed.ncbi.nlm.nih.gov/36497052" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q2QGD7-1", "protein_name": "Zinc finger protein ZXDC", "gene_name": "ZXDC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95255-1", "protein_name": "ATP-binding cassette sub-family C member 6", "gene_name": "ABCC6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q2QGD7", "url": 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Biol.", "date": "2001", "authors": "Moraes T F, Edwards R A, McKenna S, Pastushok L, Xiao W, Glover J N, Ellison M J", "reference": { "type": "PubMed", "id": "11473255", "url": "https://pubmed.ncbi.nlm.nih.gov/11473255" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P61088", "url": "https://www.uniprot.org/uniprotkb/P61088" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11473255", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1.", "journal": "Nature", "date": "2010", "authors": "Nakada S, Tai I, Panier S, Al-Hakim A, Iemura S, Juang YC, O'Donnell L, Kumakubo A, Munro M, Sicheri F, Gingras AC, Natsume T, Suda T, Durocher D", "reference": { "type": "PubMed", "id": "20725033", "url": "https://pubmed.ncbi.nlm.nih.gov/20725033" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FW1-1", "protein_name": "Ubiquitin thioesterase OTUB1", "gene_name": "OTUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P61088", "url": "https://www.uniprot.org/uniprotkb/P61088" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 265, "end_pos": 265, "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes ability to inhibit RNF168; when associated with A-88 and S-91. 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Cell", "date": "2012", "authors": "Juang YC, Landry MC, Sanches M, Vittal V, Leung CC, Ceccarelli DF, Mateo AR, Pruneda JN, Mao DY, Szilard RK, Orlicky S, Munro M, Brzovic PS, Klevit RE, Sicheri F, Durocher D", "reference": { "type": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FW1-1", "protein_name": "Ubiquitin thioesterase OTUB1", "gene_name": "OTUB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P61088", "url": "https://www.uniprot.org/uniprotkb/P61088" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 116, "end_pos": 116, "sequence_org": "A", "sequence_mut": "T", "comment": "Does not affect ability to inhibit UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 134, "end_pos": 134, "sequence_org": "T", "sequence_mut": "R", "comment": "Impairs inhibition of UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 137, "end_pos": 137, "sequence_org": "D", "sequence_mut": "G", "comment": "Impairs inhibition of UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 190, "end_pos": 190, "sequence_org": "F", "sequence_mut": "S", "comment": "Fails to inhibit ubiquitin conjugation by UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 261, "end_pos": 261, "sequence_org": "Y", "sequence_mut": "H", "comment": "Impairs inhibition of UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 263, "end_pos": 263, "sequence_org": "P", "sequence_mut": "L", "comment": "Fails to inhibit ubiquitin conjugation by UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 33, "end_pos": 33, "sequence_org": "Q", "sequence_mut": "R", "comment": "Impairs inhibition of UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 37, "end_pos": 37, "sequence_org": "I", "sequence_mut": "T", "comment": "Impairs inhibition of UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 39, "end_pos": 39, "sequence_org": "Q", "sequence_mut": "L", "comment": "Does not affect activity in DNA repair and ability to inhibit UBE2N/UBC13.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 91, "end_pos": 91, "sequence_org": "C", "sequence_mut": "A", "comment": "Prevents RNF128 autoubiquitination, and stabilizes RNF128 in vivo. Abolishes both ubiquitin-binding and adduct formation with ubiquitin-vinylsulfone. Does not affect ability to deubiquitinate RPTOR; when associated with A-88 and A-265.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "20725033", "url": "https://pubmed.ncbi.nlm.nih.gov/20725033" }, { "database": "PubMed", "id": "14661020", "url": "https://pubmed.ncbi.nlm.nih.gov/14661020" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" }, { "database": "PubMed", "id": "19211026", "url": "https://pubmed.ncbi.nlm.nih.gov/19211026" }, { "database": "PubMed", "id": "12704427", "url": "https://pubmed.ncbi.nlm.nih.gov/12704427" }, { "database": "PubMed", "id": "19383985", "url": "https://pubmed.ncbi.nlm.nih.gov/19383985" }, { "database": "PubMed", "id": "18954305", "url": "https://pubmed.ncbi.nlm.nih.gov/18954305" }, { "database": "PubMed", "id": "35927303", "url": "https://pubmed.ncbi.nlm.nih.gov/35927303" } ], "uniprot_canonical_ac": "Q96FW1-1" }, { "start_pos": 91, "end_pos": 91, "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes hydrolase activity in vitro. Does not affect ability to inhibit RNF168. Does not affect ability to deubiquitinate DEPTOR. Abolishes ability to inhibit RNF168; when associated with E-88 and A-265.", "evidence": [ { "database": "UniProtKB", "id": "Q96FW1", "url": "https://www.uniprot.org/uniprotkb/Q96FW1" }, { "database": "PubMed", "id": "20725033", "url": "https://pubmed.ncbi.nlm.nih.gov/20725033" }, { "database": "PubMed", "id": "14661020", "url": "https://pubmed.ncbi.nlm.nih.gov/14661020" }, { "database": "PubMed", "id": "22325355", "url": "https://pubmed.ncbi.nlm.nih.gov/22325355" }, { "database": "PubMed", "id": "19211026", "url": "https://pubmed.ncbi.nlm.nih.gov/19211026" }, { "database": "PubMed", "id": "12704427", "url": "https://pubmed.ncbi.nlm.nih.gov/12704427" }, { "database": "PubMed", "id": "19383985", "url": "https://pubmed.ncbi.nlm.nih.gov/19383985" }, { "database": "PubMed", "id": "18954305", "url": "https://pubmed.ncbi.nlm.nih.gov/18954305" }, { "database": "PubMed", "id": "29382726", "url": "https://pubmed.ncbi.nlm.nih.gov/29382726" } ], "uniprot_canonical_ac": "Q96FW1-1" } ], "record_id": 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"https://pubmed.ncbi.nlm.nih.gov/22367539" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FW1-1", "protein_name": "Ubiquitin thioesterase OTUB1", "gene_name": "OTUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P61088", "url": "https://www.uniprot.org/uniprotkb/P61088" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22367539", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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}, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural insights into the nanomolar affinity of RING E3 ligase ZNRF1 for Ube2N and its functional implications.", "journal": "Biochem. J.", "date": "2018", "authors": "Behera AP, Naskar P, Agarwal S, Banka PA, Poddar A, Datta AB", "reference": { "type": "PubMed", "id": "29626159", "url": "https://pubmed.ncbi.nlm.nih.gov/29626159" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8ND25-1", "protein_name": "E3 ubiquitin-protein ligase ZNRF1", "gene_name": "ZNRF1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P61088", "url": "https://www.uniprot.org/uniprotkb/P61088" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 183, "end_pos": 183, "sequence_org": "E", "sequence_mut": "A", "comment": "About 10-fold decreased binding to UBE2N.", "evidence": [ { "database": "UniProtKB", "id": "Q8ND25", 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Biochem.", "date": "1996", "authors": "Yamaguchi T, Kim NS, Sekine S, Seino H, Osaka F, Yamao F, Kato S", "reference": { "type": "PubMed", "id": "8902611", "url": "https://pubmed.ncbi.nlm.nih.gov/8902611" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P61088", "url": "https://www.uniprot.org/uniprotkb/P61088" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8902611", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { 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