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Genet.", "date": "1994", "authors": "Bollag R J, Siegfried Z, Cebra-Thomas J A, Garvey N, Davison E M, Silver L M", "reference": { "type": "PubMed", "id": "7920656", "url": "https://pubmed.ncbi.nlm.nih.gov/7920656" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q60707-1", "protein_name": "T-box transcription factor TBX2", "gene_name": "Tbx2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P70324-1", "protein_name": "T-box transcription factor TBX3", "gene_name": "Tbx3", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P70323-1", "protein_name": "T-box transcription factor TBX1", "gene_name": "Tbx1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q60707", "url": "https://www.uniprot.org/uniprotkb/Q60707" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.7920656", "abstract": "", "glycosylation": 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Shulenin S, Dean M, Kuprash DV, Nedospasov SA", "reference": { "type": "PubMed", "id": "14768054", "url": "https://pubmed.ncbi.nlm.nih.gov/14768054" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q6U7R4-1", "protein_name": "T-cell immunoglobulin and mucin domain-containing protein 4", "gene_name": "Timd4", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q6U7R4", "url": "https://www.uniprot.org/uniprotkb/Q6U7R4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.14768054", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"Adipose tissue hyperplasia with enhanced adipocyte-derived stem cell activity in Tc1(C8orf4)-deleted mice.", "journal": "Scientific reports", "date": "2016", "authors": "Jang H, Kim M, Lee S, Kim J, Woo DC, Kim KW, Song K, Lee I", "reference": { "type": "PubMed", "id": "27775060", "url": "https://pubmed.ncbi.nlm.nih.gov/27775060" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9D915-1", "protein_name": "Transcriptional and immune response regulator", "gene_name": "Tcim", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D915", "url": "https://www.uniprot.org/uniprotkb/Q9D915" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.27775060", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The murine catecholamine methyltransferase mTOMT is essential for mechanotransduction by cochlear hair cells.", "journal": "eLife", "date": "2017", "authors": "Cunningham CL, Wu Z, Jafari A, Zhao B, Schrode K, Harkins-Perry S, Lauer A, Muller U", "reference": { "type": "PubMed", "id": "28504928", "url": "https://pubmed.ncbi.nlm.nih.gov/28504928" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "A1Y9I9-1", "protein_name": "Transmembrane O-methyltransferase homolog", "gene_name": "Tomt", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "A1Y9I9", "url": "https://www.uniprot.org/uniprotkb/A1Y9I9" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 108, "end_pos": 108, "sequence_org": "Y", "sequence_mut": "A", "comment": "Is able to rescue the mechanotransduction defect of L-48.", "evidence": [ { "database": "UniProtKB", "id": "A1Y9I9", "url": "https://www.uniprot.org/uniprotkb/A1Y9I9" }, { "database": "PubMed", "id": "28504928", "url": "https://pubmed.ncbi.nlm.nih.gov/28504928" } ], "uniprot_canonical_ac": "A1Y9I9-1" }, { "start_pos": 22, "end_pos": 25, "sequence_org": "HHFR", "sequence_mut": "", "comment": "Absence of auditory brain stem response (ABR) to click stimuli demonstrates that the mice are profoundly deaf. Distortion product otoacoustic emissions (DPOAEs) are absent at 4 weeks of age at all frequencies tested. Normal hair bundle morphology as at postnatal day (P) 5 the sensory epithelia are patterned into three rows of outer hair cells (OHCs) and one row of inner hair cells (IHCs). The bundles of OHCs appear similar in size to those of wild-type mice and form a normal staircase pattern.", "evidence": [ { "database": "UniProtKB", "id": "A1Y9I9", "url": "https://www.uniprot.org/uniprotkb/A1Y9I9" }, { "database": "PubMed", "id": "28504928", "url": "https://pubmed.ncbi.nlm.nih.gov/28504928" } ], "uniprot_canonical_ac": "A1Y9I9-1" }, { "start_pos": 48, "end_pos": 48, "sequence_org": "R", "sequence_mut": "L", "comment": "In add; reduces methyltransferase activity; causes hyperkinesis, circling, head-tossing, aggression, progressive degeneration of the organ of Corti, hair cell defects and profound deafness. Distortion product otoacoustic emissions (DPOAEs) are absent at 4 weeks of age at all frequencies tested. At postnatal day (P) 5 the sensory epithelia are patterned into three rows of outer hair cells (OHCs) and one row of inner hair cells (IHCs) with no obvious structural abnormalities. The bundles of OHCs appear similar in size to those of wild-type mice and form a normal staircase pattern. The hair bundles of OHCs have a slightly more rounded morphology, especially in basal regions of the cochlea. The morphology of IHCs is not significantly altered. Hair cells are maintained in the presence of gentamicin, an aminoglycoside antibiotic that enters hair cells through their transduction channels and normally causes hair cell death. Mechanotransduction currents are very small in P4 hair cells and completely absent in P7 hair cells. Membrane potential, outward-evoked currents and nonlinear capacitance are normal in OHCs. No difference in the expression or localization of tip link proteins CDH23 and PCDH15 or ATP2B2, MYO7A, ESPN and WHRN proteins at P5-P8 in hair bundles of hair cells. No difference in the number of tip links in IHCs and OHCs at P7-P8. No difference in the levels of catecholamines, including norepinephrine, homovanillic acid (HVA) and norepinephrine, or serotonin levels in the inner ear. Loss of reverse polarity currents.", "evidence": [ { "database": "UniProtKB", "id": "A1Y9I9", "url": "https://www.uniprot.org/uniprotkb/A1Y9I9" }, { "database": "PubMed", "id": "18794526", "url": "https://pubmed.ncbi.nlm.nih.gov/18794526" }, { "database": "PubMed", "id": "28504928", "url": "https://pubmed.ncbi.nlm.nih.gov/28504928" } ], "uniprot_canonical_ac": "A1Y9I9-1" } ], "record_id": "pubmed.28504928", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Screening for genes up-regulated in 5/6 nephrectomized mouse kidney.", "journal": "Kidney Int.", "date": "1999", "authors": "Zhang H, Wada J, Kanwar Y S, Tsuchiyama Y, Hiragushi K, Hida K, Shikata K, Makino H", "reference": { "type": "PubMed", "id": "10432394", "url": "https://pubmed.ncbi.nlm.nih.gov/10432394" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ESG4-1", "protein_name": "Collectrin", "gene_name": "Cltrn", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9ESG4", "url": "https://www.uniprot.org/uniprotkb/Q9ESG4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.10432394", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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Biol. 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Biophys. Res. 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"journal": "Molecular endocrinology (Baltimore, Md.)", "date": "2006-06", "authors": "Teyssier Catherine, Ou Chen-Yin, Khetchoumian Konstantin, Losson R\u00e9gine, Stallcup Michael R", "reference": { "type": "PubMed", "id": "16322096", "url": "https://pubmed.ncbi.nlm.nih.gov/16322096" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q64127-1", "protein_name": "Transcription intermediary factor 1-alpha", "gene_name": "Trim24", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WVG6-1", "protein_name": "Histone-arginine methyltransferase CARM1", "gene_name": "Carm1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O15164-1", "protein_name": "Transcription intermediary factor 1-alpha", "gene_name": "TRIM24", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q64127", "url": "https://www.uniprot.org/uniprotkb/Q64127" } ], "common_name": "Mouse", "glygen_name": "Mouse", 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Immunol.", "date": "2000", "authors": "Bouchon A, Dietrich J, Colonna M", "reference": { "type": "PubMed", "id": "10799849", "url": "https://pubmed.ncbi.nlm.nih.gov/10799849" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q99NH8-1", "protein_name": "Triggering receptor expressed on myeloid cells 2", "gene_name": "Trem2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP99-1", "protein_name": "Triggering receptor expressed on myeloid cells 1", "gene_name": "TREM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43914-1", "protein_name": "TYRO protein tyrosine kinase-binding protein", "gene_name": "TYROBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZC2-1", "protein_name": "Triggering receptor expressed on myeloid cells 2", "gene_name": "TREM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9JKE2-1", "protein_name": "Triggering receptor expressed on myeloid cells 1", "gene_name": "Trem1", "tax_name": "Mouse" } ], "species": [ { 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