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Chem.", "date": "1993", "authors": "Ha H, Hajek P, Bedwell DM, Burrows PD", "reference": { "type": "PubMed", "id": "7685033", "url": "https://pubmed.ncbi.nlm.nih.gov/7685033" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P45880-3", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "VDAC2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P45880", "url": "https://www.uniprot.org/uniprotkb/P45880" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7685033", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 35, "end_pos": 35, "sequence_org": "K", "sequence_mut": "R", "comment": "No effect on 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 39, "end_pos": 39, "sequence_org": "Y", "sequence_mut": "F", "comment": "No effect on 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 68, "end_pos": 68, "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on 5'-dRP lyase activity. Decreased ssDNA binding. Loss of 5'-dRP lyase activity; when associated with A-35 and A-72. Decreased ssDNA binding; when associated with A-35 and A-72. No effect on structure shown by circular dichroism.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 68, "end_pos": 68, "sequence_org": "K", "sequence_mut": "Q", "comment": "Slightly reduces 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 68, "end_pos": 68, "sequence_org": "K", "sequence_mut": "R", "comment": "Slightly reduces 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 72, "end_pos": 72, "sequence_org": "K", "sequence_mut": "A", "comment": "Severely reduced 5'-dRP lyase activity. Does not affect ssDNA binding. Loss of 5'-dRP lyase activity; when associated with A-35 and A-68. Decreased ssDNA binding; when associated with A-35 and A-68. No effect on structure shown by circular dichroism.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" } ], "record_id": "pubmed.16172026", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Leu22Pro tumor-associated variant of DNA polymerase beta is dRP lyase deficient.", "journal": "Nucleic acids research", "date": "2008-02", "authors": "Dalal Shibani, Chikova Anna, Jaeger Joachim, Sweasy Joann B", "reference": { "type": "PubMed", "id": "18039710", "url": "https://pubmed.ncbi.nlm.nih.gov/18039710" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18039710", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The Asp285 variant of DNA polymerase beta extends mispaired primer termini via increased nucleotide binding.", "journal": "Biochemistry", "date": "2008-08-05", "authors": "Murphy Drew L, Kosa Jessica, Jaeger Joachim, Sweasy Joann B", "reference": { "type": "PubMed", "id": "18616290", "url": "https://pubmed.ncbi.nlm.nih.gov/18616290" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": 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Structure of the 5'-flanking region and active promoter.", "journal": "J. Biol. Chem.", "date": "1988", "authors": "Widen S G, Kedar P, Wilson S H", "reference": { "type": "PubMed", "id": "3182828", "url": "https://pubmed.ncbi.nlm.nih.gov/3182828" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.3182828", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { 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Genet.", "date": "1995", "authors": "Dobashi Y, Kubota Y, Shuin T, Torigoe S, Yao M, Hosaka M", "reference": { "type": "PubMed", "id": "7705833", "url": "https://pubmed.ncbi.nlm.nih.gov/7705833" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7705833", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The human DNA polymerase beta gene structure. 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Sciences of the United States of America", "date": "1997", "authors": "Bennett RA, Wilson DM 3rd, Wong D, Demple B", "reference": { "type": "PubMed", "id": "9207062", "url": "https://pubmed.ncbi.nlm.nih.gov/9207062" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27695-1", "protein_name": "DNA repair nuclease/redox regulator APEX1", "gene_name": "APEX1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9207062", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: evidence for an induced fit mechanism.", "journal": "Biochemistry", "date": "1997", "authors": "Sawaya M R, Prasad R, Wilson S H, Kraut J, Pelletier H", "reference": { "type": "PubMed", "id": "9287163", "url": "https://pubmed.ncbi.nlm.nih.gov/9287163" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9287163", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional analysis of the amino-terminal 8-kDa domain of DNA polymerase beta as revealed by site-directed mutagenesis. DNA binding and 5'-deoxyribose phosphate lyase activities.", "journal": "The Journal of biological chemistry", "date": "1998-05-01", "authors": "Prasad R, Beard W A, Chyan J Y, Maciejewski M W, Mullen G P, Wilson S H", "reference": { "type": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 25, "end_pos": 25, "sequence_org": "F", "sequence_mut": "W", "comment": "No effect on 5'-dRP lyase activity. Decreased ssDNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 34, "end_pos": 34, "sequence_org": "H", "sequence_mut": "G", "comment": "Decreased 5'-dRP lyase activity. Decreased ssDNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 35, "end_pos": 35, "sequence_org": "K", "sequence_mut": "A", "comment": "Decreased 5'-dRP lyase activity. Decreased ssDNA binding. Loss of 5'-dRP lyase activity; when associated with A-68 and A-72. Decreased ssDNA binding; when associated with A-68 and A-72. No effect on structure shown by circular dichroism.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 60, "end_pos": 60, "sequence_org": "K", "sequence_mut": "A", "comment": "Decreased 5'-dRP lyase activity. Decreased ssDNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 68, "end_pos": 68, "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on 5'-dRP lyase activity. Decreased ssDNA binding. Loss of 5'-dRP lyase activity; when associated with A-35 and A-72. Decreased ssDNA binding; when associated with A-35 and A-72. No effect on structure shown by circular dichroism.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 71, "end_pos": 71, "sequence_org": "E", "sequence_mut": "Q", "comment": "No effect on 5'-dRP lyase activity. No effect on structure shown by circular dichroism. No effect on ssDNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 72, "end_pos": 72, "sequence_org": "K", "sequence_mut": "A", "comment": "Severely reduced 5'-dRP lyase activity. Does not affect ssDNA binding. Loss of 5'-dRP lyase activity; when associated with A-35 and A-68. Decreased ssDNA binding; when associated with A-35 and A-68. No effect on structure shown by circular dichroism.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 75, "end_pos": 75, "sequence_org": "E", "sequence_mut": "A", "comment": "Slightly decreased 5'-dRP lyase activity. Decreased ssDNA binding. No effect on structure shown by circular dichroism.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 84, "end_pos": 84, "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 84, "end_pos": 84, "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on structure shown by circular dichroism. No effect on ssDNA binding.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 84, "end_pos": 84, "sequence_org": "K", "sequence_mut": "R", "comment": "No effect on 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" }, { "database": "PubMed", "id": "9556598", "url": "https://pubmed.ncbi.nlm.nih.gov/9556598" } ], "uniprot_canonical_ac": "P06746-1" } ], "record_id": "pubmed.9556598", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Catalytic center of DNA polymerase beta for excision of deoxyribose phosphate groups.", "journal": "Biochemistry", "date": "1998", "authors": "Matsumoto Y, Kim K, Katz DS, Feng JA", "reference": { "type": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 35, "end_pos": 35, "sequence_org": "K", "sequence_mut": "Q", "comment": "Reduces 5'-dRP lyase activity slightly.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 39, "end_pos": 39, "sequence_org": "Y", "sequence_mut": "Q", "comment": "Abolishes DNA polymerase and 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 68, "end_pos": 68, "sequence_org": "K", "sequence_mut": "Q", "comment": "Slightly reduces 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 68, "end_pos": 68, "sequence_org": "K", "sequence_mut": "R", "comment": "Slightly reduces 5'-dRP lyase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" }, { "database": "PubMed", "id": "16172026", "url": "https://pubmed.ncbi.nlm.nih.gov/16172026" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 72, 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No effect on DNA polymerase activity.", "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" }, { "database": "PubMed", "id": "9572863", "url": "https://pubmed.ncbi.nlm.nih.gov/9572863" } ], "uniprot_canonical_ac": "P06746-1" }, { "start_pos": 72, "end_pos": 72, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes 5'-dRP lyase activity. 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Substrate specificity and catalytic mechanism.", "journal": "The Journal of biological chemistry", "date": "1998-06-12", "authors": "Prasad R, Beard W A, Strauss P R, Wilson S H", "reference": { "type": "PubMed", "id": "9614142", "url": "https://pubmed.ncbi.nlm.nih.gov/9614142" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06746-1", "protein_name": "DNA polymerase beta", "gene_name": "POLB", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P06746", "url": "https://www.uniprot.org/uniprotkb/P06746" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9614142", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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site for N-glycans in glycoRNA.", "journal": "Cell", "date": "2024-09-19", "authors": "Xie Yixuan, Chai Peiyuan, Till Nicholas A, Hemberger Helena, Lebedenko Charlotta G, Porat Jennifer, Watkins Christopher P, Caldwell Reese M, George Benson M, Perr Jonathan, Bertozzi Carolyn R, Garcia Benjamin A, Flynn Ryan A", "reference": { "type": "PubMed", "id": "39173631", "url": "https://pubmed.ncbi.nlm.nih.gov/39173631" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8NBA8-1", "protein_name": "tRNA-uridine aminocarboxypropyltransferase 2", "gene_name": "DTWD2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8NBA8", "url": "https://www.uniprot.org/uniprotkb/Q8NBA8" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.39173631", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": 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U.S.A.", "date": "1992", "authors": "Ishibashi T, Bottaro DP, Chan A, Miki T, Aaronson SA", "reference": { "type": "PubMed", "id": "1281549", "url": "https://pubmed.ncbi.nlm.nih.gov/1281549" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51452-1", "protein_name": "Dual specificity protein phosphatase 3", "gene_name": "DUSP3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P51452", "url": "https://www.uniprot.org/uniprotkb/P51452" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1281549", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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Med. 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Mol. 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"Different types of repeat expansion in the TATA-binding protein gene are associated with a new form of inherited ataxia.", "journal": "Eur. J. Hum. Genet.", "date": "2001", "authors": "Z\u00fchlke C, Hellenbroich Y, Dalski A, Kononowa N, Hagenah J, Vieregge P, Riess O, Klein C, Schwinger E", "reference": { "type": "PubMed", "id": "11313753", "url": "https://pubmed.ncbi.nlm.nih.gov/11313753" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20226-1", "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P20226", "url": "https://www.uniprot.org/uniprotkb/P20226" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11313753", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SCA17, a novel autosomal dominant cerebellar ataxia caused by an expanded polyglutamine in TATA-binding protein.", "journal": "Hum. Mol. Genet.", "date": "2001", "authors": "Nakamura K, Jeong S Y, Uchihara T, Anno M, Nagashima K, Nagashima T, Ikeda S, Tsuji S, Kanazawa I", "reference": { "type": "PubMed", "id": "11448935", "url": "https://pubmed.ncbi.nlm.nih.gov/11448935" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20226-1", "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P20226", "url": "https://www.uniprot.org/uniprotkb/P20226" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11448935", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "BRFU, a TFIIB-like factor, is directly recruited to the TATA-box of polymerase III small nuclear RNA gene promoters through its interaction with TATA-binding protein.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Cabart P, Murphy S", "reference": { "type": "PubMed", "id": "11564744", "url": "https://pubmed.ncbi.nlm.nih.gov/11564744" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20226-1", "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAW0-1", "protein_name": "Transcription factor IIIB 50 kDa subunit", "gene_name": "BRF2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P20226", "url": "https://www.uniprot.org/uniprotkb/P20226" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11564744", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Trinucleotide repeats in 202 families with ataxia: a small expanded (CAG)n allele at the SCA17 locus.", "journal": "Arch. 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Genomics, evolution, and expression of TBPL2, a member of the TBP family.", "journal": "DNA Cell Biol.", "date": "2007", "authors": "Di Pietro C, Ragusa M, Duro L, Guglielmino MR, Barbagallo D, Carnemolla A, Lagana A, Buffa P, Angelica R, Rinaldi A, Calafato MS, Milicia I, Caserta C, Giugno R, Pulvirenti A, Giunta V, Rapisarda A, Di Pietro V, Grillo A, Messina A, Ferro A, Grzeschik KH, Purrello M", "reference": { "type": "PubMed", "id": "17570761", "url": "https://pubmed.ncbi.nlm.nih.gov/17570761" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20226-1", "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6SJ95-1", "protein_name": "TATA box-binding protein-like 2", "gene_name": "Tbpl2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P62380-1", "protein_name": "TATA box-binding protein-like 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properties of cloned human TATA binding protein.", "journal": "Science (New York, N.Y.)", "date": "1990-06-29", "authors": "Peterson M G, Tanese N, Pugh B F, Tjian R", "reference": { "type": "PubMed", "id": "2363050", "url": "https://pubmed.ncbi.nlm.nih.gov/2363050" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20226-1", "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P20226", "url": "https://www.uniprot.org/uniprotkb/P20226" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2363050", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", 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"journal": "Gene", "date": "2023-12-30", "authors": "Miyasaka Shinji, Kitada Ryota, Kokubo Tetsuro", "reference": { "type": "PubMed", "id": "37716588", "url": "https://pubmed.ncbi.nlm.nih.gov/37716588" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20226-1", "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P20226", "url": "https://www.uniprot.org/uniprotkb/P20226" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.37716588", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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functional interaction between the HIV-1 Tat transactivator and the TATA box binding protein in vivo.", "journal": "J. Mol. Biol.", "date": "1995", "authors": "Veschambre P, Simard P, Jalinot P", "reference": { "type": "PubMed", "id": "7608968", "url": "https://pubmed.ncbi.nlm.nih.gov/7608968" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20226-1", "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P20226", "url": "https://www.uniprot.org/uniprotkb/P20226" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7608968", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The RNA polymerase I transcription factor, upstream binding factor, interacts directly with the TATA box-binding protein.", "journal": "J. Biol. Chem.", "date": "1994", "authors": "Kwon H, Green M R", "reference": { "type": "PubMed", "id": "7982918", "url": "https://pubmed.ncbi.nlm.nih.gov/7982918" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20226-1", "protein_name": "TATA-box-binding protein", "gene_name": "TBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17480-1", "protein_name": "Nucleolar transcription factor 1", "gene_name": "UBTF", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P20226", "url": "https://www.uniprot.org/uniprotkb/P20226" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7982918", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ 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[] } ] }, { "title": "Identification and characterization of the promoter for the gene encoding human tripeptidyl-peptidase II.", "journal": "Gene", "date": "2005", "authors": "Lindas AC, Tomkinson B", "reference": { "type": "PubMed", "id": "15716107", "url": "https://pubmed.ncbi.nlm.nih.gov/15716107" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P29144-1", "protein_name": "Tripeptidyl-peptidase 2", "gene_name": "TPP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P29144", "url": "https://www.uniprot.org/uniprotkb/P29144" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15716107", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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