[ { "title": "Silence of MLK3 alleviates lipopolysaccharide-induced lung epithelial cell injury via inhibiting p53-mediated ferroptosis.", "journal": "Journal of molecular histology", "date": "2022", "authors": "Chen X, Qi G, Fang F, Miao Y, Wang L", "reference": { "type": "PubMed", "id": "35247112", "url": "https://pubmed.ncbi.nlm.nih.gov/35247112" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q80XI6-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 11", "gene_name": "Map3k11", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80XI6", "url": "https://www.uniprot.org/uniprotkb/Q80XI6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.35247112", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mixed lineage kinase 3 requires a functional CRIB domain for regulation of blood pressure, cardiac hypertrophy, and left ventricular function.", "journal": "American journal of physiology. 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Yixue Yingdewen ban", "date": "2012", "authors": "Li X, Xue B, Wang X, Sun L, Zhang T, Qu L, Zou X, Mu Y", "reference": { "type": "PubMed", "id": "22528219", "url": "https://pubmed.ncbi.nlm.nih.gov/22528219" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q922B1-1", "protein_name": "ADP-ribose glycohydrolase MACROD1", "gene_name": "Macrod1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q922B1", "url": "https://www.uniprot.org/uniprotkb/Q922B1" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.22528219", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, 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Chem.", "date": "1992", "authors": "Buschman E, Arceci R J, Croop J M, Che M, Arias I M, Housman D E, Gros P", "reference": { "type": "PubMed", "id": "1381362", "url": "https://pubmed.ncbi.nlm.nih.gov/1381362" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P21440-1", "protein_name": "Phosphatidylcholine translocator ABCB4", "gene_name": "Abcb4", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P21440", "url": "https://www.uniprot.org/uniprotkb/P21440" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.1381362", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Physical mapping, amplification, and overexpression of the mouse mdr gene family in multidrug-resistant cells.", "journal": "Mol. 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Cell", "date": "1997", "authors": "Liu J, Koyano-Nakagawa N, Amasaki Y, Saito-Ohara F, Ikeuchi T, Imai S, Takano T, Arai N, Yokota T, Arai K", "reference": { "type": "PubMed", "id": "9017603", "url": "https://pubmed.ncbi.nlm.nih.gov/9017603" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P97305-1", "protein_name": "Nuclear factor of activated T-cells, cytoplasmic 3", "gene_name": "Nfatc3", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P97305", "url": "https://www.uniprot.org/uniprotkb/P97305" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.9017603", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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PHS, Ng CCP, Leung EHW, Tan VH, Chan AKW, McAlonan G, Chan SY", "reference": { "type": "PubMed", "id": "31582721", "url": "https://pubmed.ncbi.nlm.nih.gov/31582721" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q80TE7-1", "protein_name": "Leucine-rich repeat-containing protein 7", "gene_name": "Lrrc7", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q80TE7", "url": "https://www.uniprot.org/uniprotkb/Q80TE7" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.31582721", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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Gastroenterol.", "date": "2000", "authors": "Cui Da-Xiang, Zeng Guei-Ying, Wang Feng, Xu Jun-Rong, Ren Dong-Qing, Guo Yan-Hai, Tian Fu-Rong, Yan Xiao-Jun, Hou Yu, Su Cheng-Zhi", "reference": { "type": "PubMed", "id": "11819679", "url": "https://pubmed.ncbi.nlm.nih.gov/11819679" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9CZ04-1", "protein_name": "COP9 signalosome complex subunit 7a", "gene_name": "Cops7a", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZ04", "url": "https://www.uniprot.org/uniprotkb/Q9CZ04" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.11819679", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ubiquitin-dependent degradation of Id1 and Id3 is mediated by the COP9 signalosome.", "journal": "J. Mol. Biol.", "date": "2004", "authors": "Berse M, Bounpheng M, Huang X, Christy B, Pollmann C, Dubiel W", "reference": { "type": "PubMed", "id": "15451666", "url": "https://pubmed.ncbi.nlm.nih.gov/15451666" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9CZ04-1", "protein_name": "COP9 signalosome complex subunit 7a", "gene_name": "Cops7a", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P41133-1", "protein_name": "DNA-binding protein inhibitor ID-3", "gene_name": "Id3", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O35864-1", "protein_name": "COP9 signalosome complex subunit 5", "gene_name": "Cops5", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P20067-1", "protein_name": "DNA-binding protein inhibitor ID-1", "gene_name": "Id1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CZ04", "url": "https://www.uniprot.org/uniprotkb/Q9CZ04" } ], "common_name": "Mouse", 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"journal": "Nature communications", "date": "2013", "authors": "Qiu J, Tan YW, Hagenston AM, Martel MA, Kneisel N, Skehel PA, Wyllie DJ, Bading H, Hardingham GE", "reference": { "type": "PubMed", "id": "23774321", "url": "https://pubmed.ncbi.nlm.nih.gov/23774321" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q3UMR5-1", "protein_name": "Calcium uniporter protein, mitochondrial", "gene_name": "Mcu", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q3UMR5", "url": "https://www.uniprot.org/uniprotkb/Q3UMR5" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.23774321", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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"https://pubmed.ncbi.nlm.nih.gov/24078630" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8K0B2-1", "protein_name": "Lysosomal cobalamin transport escort protein LMBD1", "gene_name": "Lmbrd1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P15208-1", "protein_name": "Insulin receptor", "gene_name": "Insr", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AZ61-1", "protein_name": "Lysosomal cobalamin transport escort protein LMBD1", "gene_name": "Lmbrd1", "tax_name": "Rat" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q8K0B2", "url": "https://www.uniprot.org/uniprotkb/Q8K0B2" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 229, "end_pos": 229, "sequence_org": "Y", "sequence_mut": "A", "comment": "Significantly reduced interaction with adapter protein complex 2 and disruption of its function in clathrin-mediated endocytosis of INSR.", "evidence": [ { "database": "UniProtKB", "id": "Q8K0B2", "url": "https://www.uniprot.org/uniprotkb/Q8K0B2" }, { "database": "PubMed", "id": "24078630", "url": "https://pubmed.ncbi.nlm.nih.gov/24078630" } ], "uniprot_canonical_ac": "Q8K0B2-1" }, { "start_pos": 291, "end_pos": 291, "sequence_org": "W", "sequence_mut": "A", "comment": "Significantly reduced interaction with adapter protein complex 2 and disruption of its function in clathrin-mediated endocytosis of INSR.", "evidence": [ { "database": "UniProtKB", "id": "Q8K0B2", "url": "https://www.uniprot.org/uniprotkb/Q8K0B2" }, { "database": "PubMed", "id": "24078630", "url": "https://pubmed.ncbi.nlm.nih.gov/24078630" } ], "uniprot_canonical_ac": "Q8K0B2-1" } ], "record_id": "pubmed.24078630", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], 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