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Sci.", "date": "1999", "authors": "Coetzee W A, Amarillo Y, Chiu J, Chow A, Lau D, McCormack T, Moreno H, Nadal M S, Ozaita A, Pountney D, Saganich M, Vega-Saenz de Miera E, Rudy B", "reference": { "type": "PubMed", "id": "10414301", "url": "https://pubmed.ncbi.nlm.nih.gov/10414301" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14721-1", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "gene_name": "KCNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03717-1", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "gene_name": "Kcnb1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q92953-1", "protein_name": "Potassium voltage-gated channel subfamily B member 2", "gene_name": "KCNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6H8H5-1", "protein_name": "Potassium voltage-gated channel subfamily B member 2", "gene_name": "Kcnb2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q63099-1", 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[] } ] }, { "title": "Structural basis of binding and inhibition of novel tarantula toxins in mammalian voltage-dependent potassium channels.", "journal": "Chem. Res. 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Muhle H, Afawi Z, Klein KM, Jayaraman V, Rajagopalan R, Goldberg E, Marsh E, Kessler S, Bergqvist C, Conlin LK, Krok BL, Thiffault I, Pendziwiat M, Helbig I, Polster T, Borggraefe I, Lemke JR, van den Boogaardt MJ, Moller RS, Koeleman BPC", "reference": { "type": "PubMed", "id": "28806457", "url": "https://pubmed.ncbi.nlm.nih.gov/28806457" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14721-1", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "gene_name": "KCNB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14721", "url": "https://www.uniprot.org/uniprotkb/Q14721" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.28806457", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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], "phosphorylation": [ { "start_pos": 593, "end_pos": 593, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q14721", "url": "https://www.uniprot.org/uniprotkb/Q14721" }, { "database": "PubMed", "id": "33124732", "url": "https://pubmed.ncbi.nlm.nih.gov/33124732" }, { "database": "iPTMnet", "id": "Q14721", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14721" } ], "site_lbl": "Ser593", "uniprot_canonical_ac": "Q14721-1" }, { "start_pos": 608, "end_pos": 608, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q92953", "url": "https://www.uniprot.org/uniprotkb/Q92953" }, { "database": "PubMed", "id": "33124732", "url": "https://pubmed.ncbi.nlm.nih.gov/33124732" }, { "database": "iPTMnet", "id": "Q92953", "url": 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"database": "iPTMnet", "id": "Q14849", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14849" }, { "database": "PubMed", "id": "18452278", "url": "https://pubmed.ncbi.nlm.nih.gov/18452278" } ], "site_lbl": "Ser209", "uniprot_canonical_ac": "Q14849-1" }, { "start_pos": 295, "end_pos": 295, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine", "evidence": [ { "database": "UniProtKB", "id": "Q7L4E1", "url": "https://www.uniprot.org/uniprotkb/Q7L4E1" }, { "database": "PubMed", "id": "33124732", "url": "https://pubmed.ncbi.nlm.nih.gov/33124732" }, { "database": "iPTMnet", "id": "Q7L4E1", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q7L4E1" } ], "site_lbl": "Ser295", "uniprot_canonical_ac": "Q7L4E1-1" }, { "start_pos": 160, "end_pos": 160, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine", "evidence": [ { "database": "UniProtKB", "id": "Q96TC7", "url": 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Impairs the interactions of the MSP domain with the phosphorylated FFAT motif of STARD3.", "evidence": [ { "database": "UniProtKB", "id": "O95292", "url": "https://www.uniprot.org/uniprotkb/O95292" }, { "database": "PubMed", "id": "33124732", "url": "https://pubmed.ncbi.nlm.nih.gov/33124732" } ], "uniprot_canonical_ac": "O95292-1" }, { "start_pos": 50, "end_pos": 50, "sequence_org": "K", "sequence_mut": "L", "comment": "Impairs the interaction of the MSP domain with the phosphorylated FFAT motif of STARD3. Does not affect its ability to interact with the conventional FFAT motif of OSBPL1A.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0L0", "url": "https://www.uniprot.org/uniprotkb/Q9P0L0" }, { "database": "PubMed", "id": "33124732", "url": "https://pubmed.ncbi.nlm.nih.gov/33124732" } ], "uniprot_canonical_ac": "Q9P0L0-1" }, { "start_pos": 209, "end_pos": 209, "sequence_org": "S", "sequence_mut": "A", "comment": "Impairs VAPA and VAPB interaction. Does not affect endoplasmic reticulum membrane location of VAPA, VAPB and MOSPD2. Is unable to make ER-endosome contacts. Does not accumulate cholesterol in late endosomes (LEs). Does not interact with MOSPD2.", "evidence": [ { "database": "UniProtKB", "id": "Q14849", "url": "https://www.uniprot.org/uniprotkb/Q14849" }, { "database": "PubMed", "id": "33124732", "url": "https://pubmed.ncbi.nlm.nih.gov/33124732" } ], "uniprot_canonical_ac": "Q14849-1" }, { "start_pos": 209, "end_pos": 209, "sequence_org": "S", "sequence_mut": "D", "comment": "Does not affect VAPA and VAPB interactions; when associated with A-210. Does not interact with VAPA and VAPB. Recruits VAPA and VAPB around the endosome; when associated with A-210. Restores cholesterol accumulation in late endosomes; when associated with A-210. Moderately interacts with MOSPD2. Almost impairs interaction with MOSPD2; when associated with A-210.", "evidence": [ { "database": "UniProtKB", "id": "Q14849", "url": "https://www.uniprot.org/uniprotkb/Q14849" }, { "database": "PubMed", "id": "33124732", "url": "https://pubmed.ncbi.nlm.nih.gov/33124732" } ], "uniprot_canonical_ac": "Q14849-1" }, { "start_pos": 210, "end_pos": 210, "sequence_org": "P", "sequence_mut": "A", "comment": "Does not affect VAPA and VAPB interactions; when associated with D-209. Improve VAPA interaction. Does not interact with VAPA and VAPB. Recruits VAPA and VAPB around the endosome; when associated with D-209. Restores cholesterol accumulation in late endosomes; when associated with A-209. 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0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Compound heterozygous KCNV2 variants contribute to cone dystrophy with supernormal rod responses in a Chinese family.", "journal": "Mol. Genet. Genomic Med.", "date": "2021", "authors": "Liu M, Zhu Y, Huang L, Jiang W, Wu N, Song Y, Lu Y, Ma Y", "reference": { "type": "PubMed", "id": "34535971", "url": "https://pubmed.ncbi.nlm.nih.gov/34535971" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14721-1", "protein_name": "Potassium voltage-gated channel subfamily B member 1", "gene_name": "KCNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TDN2-1", "protein_name": "Potassium voltage-gated channel subfamily V member 2", "gene_name": "KCNV2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14721", "url": "https://www.uniprot.org/uniprotkb/Q14721" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34535971", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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Biol.", "date": "2000", "authors": "Santelli E, Richmond T J", "reference": { "type": "PubMed", "id": "10715212", "url": "https://pubmed.ncbi.nlm.nih.gov/10715212" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q02078-1", "protein_name": "Myocyte-specific enhancer factor 2A", "gene_name": "MEF2A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q02078", "url": "https://www.uniprot.org/uniprotkb/Q02078" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10715212", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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"date": "2003", "authors": "Cox DM, Du M, Marback M, Yang EC, Chan J, Siu KW, McDermott JC", "reference": { "type": "PubMed", "id": "12586839", "url": "https://pubmed.ncbi.nlm.nih.gov/12586839" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q02078-1", "protein_name": "Myocyte-specific enhancer factor 2A", "gene_name": "MEF2A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q02078", "url": "https://www.uniprot.org/uniprotkb/Q02078" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 255, "end_pos": 255, "sequence_org": "S", "sequence_mut": "A", "comment": "Slightly increased MEF2A protein level.", "evidence": [ { "database": "UniProtKB", "id": "Q02078", "url": "https://www.uniprot.org/uniprotkb/Q02078" }, { "database": "PubMed", "id": "12586839", "url": "https://pubmed.ncbi.nlm.nih.gov/12586839" 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Med. Genet.", "date": "2006", "authors": "Gonz\u00e1lez P, Garc\u00eda-Castro M, Reguero J R, Batalla A, Ord\u00f3\u00f1ez A G, Palop R L, Lozano I, Montes M, Alvarez V, Coto E", "reference": { "type": "PubMed", "id": "15958500", "url": "https://pubmed.ncbi.nlm.nih.gov/15958500" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q02078-1", "protein_name": "Myocyte-specific enhancer factor 2A", "gene_name": "MEF2A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q02078", "url": "https://www.uniprot.org/uniprotkb/Q02078" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15958500", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A calcium-regulated MEF2 sumoylation switch controls postsynaptic differentiation.", "journal": "Science (New York, N.Y.)", "date": "2006", "authors": "Shalizi A, Gaudilliere B, Yuan Z, Stegmuller J, Shirogane T, Ge Q, Tan Y, Schulman B, Harper JW, Bonni A", "reference": { "type": "PubMed", "id": "16484498", "url": "https://pubmed.ncbi.nlm.nih.gov/16484498" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q02078-1", "protein_name": "Myocyte-specific enhancer factor 2A", "gene_name": "MEF2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q2MJT0-1", "protein_name": "Myocyte-specific enhancer factor 2A", "gene_name": "Mef2a", "tax_name": "Rat" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q02078", "url": "https://www.uniprot.org/uniprotkb/Q02078" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 408, "end_pos": 408, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; 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