[
    {
        "title": "IGF-binding proteins are multifunctional and act via IGF-dependent and -independent mechanisms.",
        "journal": "The Journal of endocrinology",
        "date": "2002",
        "authors": "Mohan S, Baylink DJ",
        "reference": {
            "type": "PubMed",
            "id": "12379487",
            "url": "https://pubmed.ncbi.nlm.nih.gov/12379487"
        },
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        "title": "Cellular actions of the insulin-like growth factor binding proteins.",
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        "date": "2002",
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    {
        "title": "Amino- and carboxyl-terminal fragments of insulin-like growth factor (IGF) binding protein-3 cooperate to bind IGFs with high affinity and inhibit IGF receptor interactions.",
        "journal": "Endocrinology",
        "date": "2003",
        "authors": "Payet LD, Wang XH, Baxter RC, Firth SM",
        "reference": {
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            "id": "12810533",
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    {
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    {
        "title": "Structural determinants for binary and ternary complex formation between insulin-like growth factor-I (IGF-I) and IGF binding protein-3.",
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                "tax_name": "Human"
            },
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                "tax_name": "Human"
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                "protein_name": "Disintegrin and metalloproteinase domain-containing protein 10",
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                "protein_name": "Alpha-1-antitrypsin",
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        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q14766",
                        "url": "https://www.uniprot.org/uniprotkb/Q14766"
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                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.15126567",
        "abstract": "",
        "glycosylation": [],
        "mutagenesis": [],
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        "phosphorylation": [],
        "glycation": [],
        "section_stats": [
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    {
        "title": "Structural basis of heteromeric smad protein assembly in TGF-beta signaling.",
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    {
        "title": "Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding.",
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                "uniprot_canonical_ac": "O14791-1",
                "protein_name": "Apolipoprotein L1",
                "gene_name": "APOL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCE9-1",
                "protein_name": "Anoctamin-8",
                "gene_name": "ANO8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04114-1",
                "protein_name": "Apolipoprotein B-100",
                "gene_name": "APOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02751-15",
                "protein_name": "Fibronectin",
                "gene_name": "FN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01008-1",
                "protein_name": "Antithrombin-III",
                "gene_name": "SERPINC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6UX39-1",
                "protein_name": "Amelotin",
                "gene_name": "AMTN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01210-1",
                "protein_name": "Proenkephalin-A",
                "gene_name": "PENK",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q02818-1",
                "protein_name": "Nucleobindin-1",
                "gene_name": "NUCB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q07065-1",
                "protein_name": "Cytoskeleton-associated protein 4",
                "gene_name": "CKAP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02765-1",
                "protein_name": "Alpha-2-HS-glycoprotein",
                "gene_name": "AHSG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02679-1",
                "protein_name": "Fibrinogen gamma chain",
                "gene_name": "FGG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07237-1",
                "protein_name": "Protein disulfide-isomerase",
                "gene_name": "P4HB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14393-2",
                "protein_name": "Growth arrest-specific protein 6",
                "gene_name": "GAS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51654-1",
                "protein_name": "Glypican-3",
                "gene_name": "GPC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NBJ4-1",
                "protein_name": "Golgi membrane protein 1",
                "gene_name": "GOLM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09603-1",
                "protein_name": "Macrophage colony-stimulating factor 1",
                "gene_name": "CSF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05231-1",
                "protein_name": "Interleukin-6",
                "gene_name": "IL6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P988-1",
                "protein_name": "Palmitoleoyl-protein carboxylesterase NOTUM",
                "gene_name": "NOTUM",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P03956-1",
                "protein_name": "Interstitial collagenase",
                "gene_name": "MMP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13421-3",
                "protein_name": "Mesothelin",
                "gene_name": "MSLN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13219-1",
                "protein_name": "Pappalysin-1",
                "gene_name": "PAPPA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23327-1",
                "protein_name": "Sarcoplasmic reticulum histidine-rich calcium-binding protein",
                "gene_name": "HRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXD2-1",
                "protein_name": "Secretogranin-3",
                "gene_name": "SCG3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01033-1",
                "protein_name": "Metalloproteinase inhibitor 1",
                "gene_name": "TIMP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17936-1",
                "protein_name": "Insulin-like growth factor-binding protein 3",
                "gene_name": "IGFBP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02649-1",
                "protein_name": "Apolipoprotein E",
                "gene_name": "APOE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13521-1",
                "protein_name": "Secretogranin-2",
                "gene_name": "SCG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08311-1",
                "protein_name": "Cathepsin G",
                "gene_name": "CTSG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P00450-1",
                "protein_name": "Ceruloplasmin",
                "gene_name": "CP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10451-1",
                "protein_name": "Osteopontin",
                "gene_name": "SPP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0L4-1",
                "protein_name": "Complement C4-A",
                "gene_name": "C4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00622-1",
                "protein_name": "CCN family member 1",
                "gene_name": "CCN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20151-1",
                "protein_name": "Kallikrein-2",
                "gene_name": "KLK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07942-1",
                "protein_name": "Laminin subunit beta-1",
                "gene_name": "LAMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06870-1",
                "protein_name": "Kallikrein-1",
                "gene_name": "KLK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKR3-1",
                "protein_name": "Kallikrein-13",
                "gene_name": "KLK13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P11047-1",
                "protein_name": "Laminin subunit gamma-1",
                "gene_name": "LAMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43493-2",
                "protein_name": "Trans-Golgi network integral membrane protein 2",
                "gene_name": "TGOLN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P19823-1",
                "protein_name": "Inter-alpha-trypsin inhibitor heavy chain H2",
                "gene_name": "ITIH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13103-1",
                "protein_name": "Secreted phosphoprotein 24",
                "gene_name": "SPP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15240-1",
                "protein_name": "Neurosecretory protein VGF",
                "gene_name": "VGF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BU40-6",
                "protein_name": "Chordin-like protein 1",
                "gene_name": "CHRDL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P24593-1",
                "protein_name": "Insulin-like growth factor-binding protein 5",
                "gene_name": "IGFBP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14703-1",
                "protein_name": "Membrane-bound transcription factor site-1 protease",
                "gene_name": "MBTPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXP8-1",
                "protein_name": "Pappalysin-2",
                "gene_name": "PAPPA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02652-1",
                "protein_name": "Apolipoprotein A-II",
                "gene_name": "APOA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NBP7-1",
                "protein_name": "Proprotein convertase subtilisin/kexin type 9",
                "gene_name": "PCSK9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXL6-1",
                "protein_name": "Extracellular serine/threonine protein kinase FAM20C",
                "gene_name": "FAM20C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35858-1",
                "protein_name": "Insulin-like growth factor-binding protein complex acid labile subunit",
                "gene_name": "IGFALS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6Q788-1",
                "protein_name": "Apolipoprotein A-V",
                "gene_name": "APOA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P00747-1",
                "protein_name": "Plasminogen",
                "gene_name": "PLG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02768-1",
                "protein_name": "Albumin",
                "gene_name": "ALB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07288-1",
                "protein_name": "Prostate-specific antigen",
                "gene_name": "KLK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NP70-1",
                "protein_name": "Ameloblastin",
                "gene_name": "AMBN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JRA6-1",
                "protein_name": "Transport and Golgi organization protein 1 homolog",
                "gene_name": "MIA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04070-1",
                "protein_name": "Vitamin K-dependent protein C",
                "gene_name": "PROC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P34741-1",
                "protein_name": "Syndecan-2",
                "gene_name": "SDC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01034-1",
                "protein_name": "Cystatin-C",
                "gene_name": "CST3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H8M9-1",
                "protein_name": "Protein eva-1 homolog A",
                "gene_name": "EVA1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P12259-1",
                "protein_name": "Coagulation factor V",
                "gene_name": "F5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRM1-1",
                "protein_name": "Enamelin",
                "gene_name": "ENAM",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BTY2-1",
                "protein_name": "Plasma alpha-L-fucosidase",
                "gene_name": "FUCA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02787-1",
                "protein_name": "Serotransferrin",
                "gene_name": "TF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK55-1",
                "protein_name": "Protein Z-dependent protease inhibitor",
                "gene_name": "SERPINA10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13611-1",
                "protein_name": "Versican core protein",
                "gene_name": "VCAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UP2-1",
                "protein_name": "Kinectin",
                "gene_name": "KTN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01042-1",
                "protein_name": "Kininogen-1",
                "gene_name": "KNG1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P12644-1",
                "protein_name": "Bone morphogenetic protein 4",
                "gene_name": "BMP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95972-1",
                "protein_name": "Bone morphogenetic protein 15",
                "gene_name": "BMP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N4F0-1",
                "protein_name": "BPI fold-containing family B member 2",
                "gene_name": "BPIFB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P19022-1",
                "protein_name": "Cadherin-2",
                "gene_name": "CDH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43852-1",
                "protein_name": "Calumenin",
                "gene_name": "CALU",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14515-1",
                "protein_name": "SPARC-like protein 1",
                "gene_name": "SPARCL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08253-1",
                "protein_name": "72 kDa type IV collagenase",
                "gene_name": "MMP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BRK3-1",
                "protein_name": "Matrix remodeling-associated protein 8",
                "gene_name": "MXRA8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16270-1",
                "protein_name": "Insulin-like growth factor-binding protein 7",
                "gene_name": "IGFBP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96AD5-1",
                "protein_name": "Patatin-like phospholipase domain-containing protein 2",
                "gene_name": "PNPLA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05546-1",
                "protein_name": "Heparin cofactor 2",
                "gene_name": "SERPIND1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95084-1",
                "protein_name": "Serine protease 23",
                "gene_name": "PRSS23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00391-1",
                "protein_name": "Sulfhydryl oxidase 1",
                "gene_name": "QSOX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15084-1",
                "protein_name": "Protein disulfide-isomerase A6",
                "gene_name": "PDIA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15232-1",
                "protein_name": "Matrilin-3",
                "gene_name": "MATN3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O76061-1",
                "protein_name": "Stanniocalcin-2",
                "gene_name": "STC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08582-1",
                "protein_name": "Melanotransferrin",
                "gene_name": "MELTF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N114-1",
                "protein_name": "Protein shisa-5",
                "gene_name": "SHISA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09382-1",
                "protein_name": "Galectin-1",
                "gene_name": "LGALS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15293-1",
                "protein_name": "Reticulocalbin-1",
                "gene_name": "RCN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01024-1",
                "protein_name": "Complement C3",
                "gene_name": "C3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00255-2",
                "protein_name": "Menin",
                "gene_name": "MEN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13316-1",
                "protein_name": "Dentin matrix acidic phosphoprotein 1",
                "gene_name": "DMP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13217-1",
                "protein_name": "DnaJ homolog subfamily C member 3",
                "gene_name": "DNAJC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35555-1",
                "protein_name": "Fibrillin-1",
                "gene_name": "FBN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05060-1",
                "protein_name": "Secretogranin-1",
                "gene_name": "CHGB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08833-1",
                "protein_name": "Insulin-like growth factor-binding protein 1",
                "gene_name": "IGFBP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14314-1",
                "protein_name": "Glucosidase 2 subunit beta",
                "gene_name": "PRKCSH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20718-1",
                "protein_name": "Granzyme H",
                "gene_name": "GZMH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZV9-1",
                "protein_name": "Fibroblast growth factor 23",
                "gene_name": "FGF23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P18065-1",
                "protein_name": "Insulin-like growth factor-binding protein 2",
                "gene_name": "IGFBP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01344-1",
                "protein_name": "Insulin-like growth factor 2",
                "gene_name": "IGF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MK3-1",
                "protein_name": "Pseudokinase FAM20A",
                "gene_name": "FAM20A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05019-1",
                "protein_name": "Insulin-like growth factor 1",
                "gene_name": "IGF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P24592-1",
                "protein_name": "Insulin-like growth factor-binding protein 6",
                "gene_name": "IGFBP6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P22692-1",
                "protein_name": "Insulin-like growth factor-binding protein 4",
                "gene_name": "IGFBP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q08431-1",
                "protein_name": "Lactadherin",
                "gene_name": "MFGE8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55268-1",
                "protein_name": "Laminin subunit beta-2",
                "gene_name": "LAMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQ76-1",
                "protein_name": "Matrix extracellular phosphoglycoprotein",
                "gene_name": "MEPE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM21-1",
                "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A",
                "gene_name": "MGAT4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P24821-1",
                "protein_name": "Tenascin",
                "gene_name": "TNC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O76024-1",
                "protein_name": "Wolframin",
                "gene_name": "WFS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02771-1",
                "protein_name": "Alpha-fetoprotein",
                "gene_name": "AFP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14625-1",
                "protein_name": "Endoplasmin",
                "gene_name": "HSP90B1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCB0-1",
                "protein_name": "von Willebrand factor A domain-containing protein 1",
                "gene_name": "VWA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05067-1",
                "protein_name": "Amyloid-beta precursor protein",
                "gene_name": "APP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q06481-1",
                "protein_name": "Amyloid beta precursor like protein 2",
                "gene_name": "APLP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14672-1",
                "protein_name": "Disintegrin and metalloproteinase domain-containing protein 10",
                "gene_name": "ADAM10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02647-1",
                "protein_name": "Apolipoprotein A-I",
                "gene_name": "APOA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01009-1",
                "protein_name": "Alpha-1-antitrypsin",
                "gene_name": "SERPINA1",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q14766",
                        "url": "https://www.uniprot.org/uniprotkb/Q14766"
                    }
                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
            }
        ],
        "record_id": "pubmed.15525596",
        "abstract": "",
        "glycosylation": [],
        "mutagenesis": [],
        "snv": [],
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            "id": "15642270",
            "url": "https://pubmed.ncbi.nlm.nih.gov/15642270"
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        "referenced_glycans": [],
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                "protein_name": "Latent-transforming growth factor beta-binding protein 1",
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                "protein_name": "Amelogenin, X isoform",
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                "tax_name": "Human"
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                "protein_name": "Fibrinogen alpha chain",
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                "tax_name": "Human"
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                "protein_name": "Follistatin-related protein 1",
                "gene_name": "FSTL1",
                "tax_name": "Human"
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                "protein_name": "Follistatin-related protein 3",
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                "tax_name": "Human"
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                "protein_name": "Apolipoprotein L1",
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                "tax_name": "Human"
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                "protein_name": "Anoctamin-8",
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                "protein_name": "Apolipoprotein B-100",
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                "protein_name": "Fibronectin",
                "gene_name": "FN1",
                "tax_name": "Human"
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                "protein_name": "Antithrombin-III",
                "gene_name": "SERPINC1",
                "tax_name": "Human"
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                "protein_name": "Proenkephalin-A",
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    {
        "title": "Quantitative analysis of insulin-like growth factor-modulated proteolysis of insulin-like growth factor binding protein-4 and -5 by pregnancy-associated plasma protein-A.",
        "journal": "Biochemistry",
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        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
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                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.17249697",
        "abstract": "",
        "glycosylation": [],
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    {
        "title": "LTBP-2 specifically interacts with the amino-terminal region of fibrillin-1 and competes with LTBP-1 for binding to this microfibrillar protein.",
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        "date": "2007",
        "authors": "Hirani R, Hanssen E, Gibson MA",
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        "abstract": "",
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        "title": "Regulation of insulin-like growth factor (IGF) bioactivity by sequential proteolytic cleavage of IGF binding protein-4 and -5.",
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        "date": "2007",
        "authors": "Laursen LS, Kjaer-Sorensen K, Andersen MH, Oxvig C",
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    {
        "title": "Cooperativity of the N- and C-terminal domains of insulin-like growth factor (IGF) binding protein 2 in IGF binding.",
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    {
        "title": "TGFbeta1 (Leu10Pro), p53 (Arg72Pro) can predict for increased risk for breast cancer in south Indian women and TGFbeta1 Pro (Leu10Pro) allele predicts response to neo-adjuvant chemo-radiotherapy.",
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        "title": "TGF-beta 1 binding protein: a component of the large latent complex of TGF-beta 1 with multiple repeat sequences.",
        "journal": "Cell",
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        "authors": "Kanzaki T, Olofsson A, Moren A, Wernstedt C, Hellman U, Miyazono K, Claesson-Welsh L, Heldin CH",
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    {
        "title": "A Single Kinase Generates the Majority of the Secreted Phosphoproteome.",
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        "date": "2015",
        "authors": "Tagliabracci VS, Wiley SE, Guo X, Kinch LN, Durrant E, Wen J, Xiao J, Cui J, Nguyen KB, Engel JL, Coon JJ, Grishin N, Pinna LA, Pagliarini DJ, Dixon JE",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04114-1",
                "protein_name": "Apolipoprotein B-100",
                "gene_name": "APOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02751-15",
                "protein_name": "Fibronectin",
                "gene_name": "FN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01008-1",
                "protein_name": "Antithrombin-III",
                "gene_name": "SERPINC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6UX39-1",
                "protein_name": "Amelotin",
                "gene_name": "AMTN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01210-1",
                "protein_name": "Proenkephalin-A",
                "gene_name": "PENK",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q02818-1",
                "protein_name": "Nucleobindin-1",
                "gene_name": "NUCB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q07065-1",
                "protein_name": "Cytoskeleton-associated protein 4",
                "gene_name": "CKAP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02765-1",
                "protein_name": "Alpha-2-HS-glycoprotein",
                "gene_name": "AHSG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02679-1",
                "protein_name": "Fibrinogen gamma chain",
                "gene_name": "FGG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07237-1",
                "protein_name": "Protein disulfide-isomerase",
                "gene_name": "P4HB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14393-2",
                "protein_name": "Growth arrest-specific protein 6",
                "gene_name": "GAS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51654-1",
                "protein_name": "Glypican-3",
                "gene_name": "GPC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NBJ4-1",
                "protein_name": "Golgi membrane protein 1",
                "gene_name": "GOLM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09603-1",
                "protein_name": "Macrophage colony-stimulating factor 1",
                "gene_name": "CSF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05231-1",
                "protein_name": "Interleukin-6",
                "gene_name": "IL6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P988-1",
                "protein_name": "Palmitoleoyl-protein carboxylesterase NOTUM",
                "gene_name": "NOTUM",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P03956-1",
                "protein_name": "Interstitial collagenase",
                "gene_name": "MMP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13421-3",
                "protein_name": "Mesothelin",
                "gene_name": "MSLN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13219-1",
                "protein_name": "Pappalysin-1",
                "gene_name": "PAPPA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23327-1",
                "protein_name": "Sarcoplasmic reticulum histidine-rich calcium-binding protein",
                "gene_name": "HRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXD2-1",
                "protein_name": "Secretogranin-3",
                "gene_name": "SCG3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01033-1",
                "protein_name": "Metalloproteinase inhibitor 1",
                "gene_name": "TIMP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17936-1",
                "protein_name": "Insulin-like growth factor-binding protein 3",
                "gene_name": "IGFBP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02649-1",
                "protein_name": "Apolipoprotein E",
                "gene_name": "APOE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13521-1",
                "protein_name": "Secretogranin-2",
                "gene_name": "SCG2",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P08311-1",
                "protein_name": "Cathepsin G",
                "gene_name": "CTSG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P00450-1",
                "protein_name": "Ceruloplasmin",
                "gene_name": "CP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10451-1",
                "protein_name": "Osteopontin",
                "gene_name": "SPP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0L4-1",
                "protein_name": "Complement C4-A",
                "gene_name": "C4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00622-1",
                "protein_name": "CCN family member 1",
                "gene_name": "CCN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20151-1",
                "protein_name": "Kallikrein-2",
                "gene_name": "KLK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07942-1",
                "protein_name": "Laminin subunit beta-1",
                "gene_name": "LAMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06870-1",
                "protein_name": "Kallikrein-1",
                "gene_name": "KLK1",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q9UKR3-1",
                "protein_name": "Kallikrein-13",
                "gene_name": "KLK13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P11047-1",
                "protein_name": "Laminin subunit gamma-1",
                "gene_name": "LAMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43493-2",
                "protein_name": "Trans-Golgi network integral membrane protein 2",
                "gene_name": "TGOLN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P19823-1",
                "protein_name": "Inter-alpha-trypsin inhibitor heavy chain H2",
                "gene_name": "ITIH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13103-1",
                "protein_name": "Secreted phosphoprotein 24",
                "gene_name": "SPP2",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O15240-1",
                "protein_name": "Neurosecretory protein VGF",
                "gene_name": "VGF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BU40-6",
                "protein_name": "Chordin-like protein 1",
                "gene_name": "CHRDL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P24593-1",
                "protein_name": "Insulin-like growth factor-binding protein 5",
                "gene_name": "IGFBP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14703-1",
                "protein_name": "Membrane-bound transcription factor site-1 protease",
                "gene_name": "MBTPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXP8-1",
                "protein_name": "Pappalysin-2",
                "gene_name": "PAPPA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02652-1",
                "protein_name": "Apolipoprotein A-II",
                "gene_name": "APOA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NBP7-1",
                "protein_name": "Proprotein convertase subtilisin/kexin type 9",
                "gene_name": "PCSK9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXL6-1",
                "protein_name": "Extracellular serine/threonine protein kinase FAM20C",
                "gene_name": "FAM20C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35858-1",
                "protein_name": "Insulin-like growth factor-binding protein complex acid labile subunit",
                "gene_name": "IGFALS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6Q788-1",
                "protein_name": "Apolipoprotein A-V",
                "gene_name": "APOA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P00747-1",
                "protein_name": "Plasminogen",
                "gene_name": "PLG",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P02768-1",
                "protein_name": "Albumin",
                "gene_name": "ALB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07288-1",
                "protein_name": "Prostate-specific antigen",
                "gene_name": "KLK3",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9NP70-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q5JRA6-1",
                "protein_name": "Transport and Golgi organization protein 1 homolog",
                "gene_name": "MIA3",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P04070-1",
                "protein_name": "Vitamin K-dependent protein C",
                "gene_name": "PROC",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P34741-1",
                "protein_name": "Syndecan-2",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P01034-1",
                "protein_name": "Cystatin-C",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9H8M9-1",
                "protein_name": "Protein eva-1 homolog A",
                "gene_name": "EVA1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6WN34-1",
                "protein_name": "Chordin-like protein 2",
                "gene_name": "CHRDL2",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P12259-1",
                "protein_name": "Coagulation factor V",
                "gene_name": "F5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRM1-1",
                "protein_name": "Enamelin",
                "gene_name": "ENAM",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q9BTY2-1",
                "protein_name": "Plasma alpha-L-fucosidase",
                "gene_name": "FUCA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02787-1",
                "protein_name": "Serotransferrin",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9UK55-1",
                "protein_name": "Protein Z-dependent protease inhibitor",
                "gene_name": "SERPINA10",
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            {
                "uniprot_canonical_ac": "P13611-1",
                "protein_name": "Versican core protein",
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                "uniprot_canonical_ac": "Q86UP2-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P01042-1",
                "protein_name": "Kininogen-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "P12644-1",
                "protein_name": "Bone morphogenetic protein 4",
                "gene_name": "BMP4",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "O95972-1",
                "protein_name": "Bone morphogenetic protein 15",
                "gene_name": "BMP15",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8N4F0-1",
                "protein_name": "BPI fold-containing family B member 2",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "P19022-1",
                "protein_name": "Cadherin-2",
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            {
                "uniprot_canonical_ac": "O43852-1",
                "protein_name": "Calumenin",
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            {
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                "protein_name": "72 kDa type IV collagenase",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9BRK3-1",
                "protein_name": "Matrix remodeling-associated protein 8",
                "gene_name": "MXRA8",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q16270-1",
                "protein_name": "Insulin-like growth factor-binding protein 7",
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            {
                "uniprot_canonical_ac": "Q96AD5-1",
                "protein_name": "Patatin-like phospholipase domain-containing protein 2",
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            {
                "uniprot_canonical_ac": "P05546-1",
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            {
                "uniprot_canonical_ac": "O95084-1",
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            {
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            {
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O76061-1",
                "protein_name": "Stanniocalcin-2",
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                "uniprot_canonical_ac": "P08582-1",
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            {
                "uniprot_canonical_ac": "Q8N114-1",
                "protein_name": "Protein shisa-5",
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            {
                "uniprot_canonical_ac": "P09382-1",
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            {
                "uniprot_canonical_ac": "Q15293-1",
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            {
                "uniprot_canonical_ac": "P01024-1",
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            {
                "uniprot_canonical_ac": "O00255-2",
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            {
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            {
                "uniprot_canonical_ac": "Q13217-1",
                "protein_name": "DnaJ homolog subfamily C member 3",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P02810-1",
                "protein_name": "Salivary acidic proline-rich phosphoprotein 1/2",
                "gene_name": "PRH1; PRH2; PRR4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05060-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P08833-1",
                "protein_name": "Insulin-like growth factor-binding protein 1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P14314-1",
                "protein_name": "Glucosidase 2 subunit beta",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P20718-1",
                "protein_name": "Granzyme H",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZV9-1",
                "protein_name": "Fibroblast growth factor 23",
                "gene_name": "FGF23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P18065-1",
                "protein_name": "Insulin-like growth factor-binding protein 2",
                "gene_name": "IGFBP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01344-1",
                "protein_name": "Insulin-like growth factor 2",
                "gene_name": "IGF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MK3-1",
                "protein_name": "Pseudokinase FAM20A",
                "gene_name": "FAM20A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05019-1",
                "protein_name": "Insulin-like growth factor 1",
                "gene_name": "IGF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P24592-1",
                "protein_name": "Insulin-like growth factor-binding protein 6",
                "gene_name": "IGFBP6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P22692-1",
                "protein_name": "Insulin-like growth factor-binding protein 4",
                "gene_name": "IGFBP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q08431-1",
                "protein_name": "Lactadherin",
                "gene_name": "MFGE8",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P55268-1",
                "protein_name": "Laminin subunit beta-2",
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            },
            {
                "uniprot_canonical_ac": "Q9NQ76-1",
                "protein_name": "Matrix extracellular phosphoglycoprotein",
                "gene_name": "MEPE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM21-1",
                "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A",
                "gene_name": "MGAT4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P24821-1",
                "protein_name": "Tenascin",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O76024-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P02771-1",
                "protein_name": "Alpha-fetoprotein",
                "gene_name": "AFP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14625-1",
                "protein_name": "Endoplasmin",
                "gene_name": "HSP90B1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCB0-1",
                "protein_name": "von Willebrand factor A domain-containing protein 1",
                "gene_name": "VWA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05067-1",
                "protein_name": "Amyloid-beta precursor protein",
                "gene_name": "APP",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q06481-1",
                "protein_name": "Amyloid beta precursor like protein 2",
                "gene_name": "APLP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14672-1",
                "protein_name": "Disintegrin and metalloproteinase domain-containing protein 10",
                "gene_name": "ADAM10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02647-1",
                "protein_name": "Apolipoprotein A-I",
                "gene_name": "APOA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01009-1",
                "protein_name": "Alpha-1-antitrypsin",
                "gene_name": "SERPINA1",
                "tax_name": "Human"
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        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q14766",
                        "url": "https://www.uniprot.org/uniprotkb/Q14766"
                    }
                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
            }
        ],
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                    {
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                    {
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                    {
                        "database": "PubMed",
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                    {
                        "database": "PubMed",
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                    {
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                    {
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                    {
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                    {
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                "kinase_gene_name": "",
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                    {
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                    {
                        "database": "PubMed",
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                    {
                        "database": "PubMed",
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                    {
                        "database": "PubMed",
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                    {
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                "kinase_gene_name": "",
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                    {
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                    {
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                "start_pos": 590,
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                    {
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                "start_pos": 719,
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                "kinase_gene_name": "",
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                    {
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                    {
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                    {
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                    {
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                    {
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                "kinase_gene_name": "",
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                    {
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                    {
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                    {
                        "database": "PubMed",
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                    {
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                    {
                        "database": "PubMed",
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                "site_lbl": "Ser2116",
                "uniprot_canonical_ac": "P13611-1"
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                "relation": "attached",
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            {
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                "site_seq": "N",
                "relation": "attached",
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                    {
                        "id": "26091039",
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                    {
                        "id": "24190977",
                        "database": "PubMed",
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                    {
                        "id": "GLY_000143",
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                    {
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                        "database": "PubMed",
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                "comment": "Impaired secretion; when associated with A-335 and A-470.",
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                    {
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                ],
                "uniprot_canonical_ac": "Q8IXL6-1"
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            {
                "start_pos": 335,
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                "sequence_org": "N",
                "sequence_mut": "A",
                "comment": "Impaired secretion; when associated with A-101 and A-470.",
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                "sequence_mut": "A",
                "comment": "Impaired secretion; when associated with A-101 and A-335.",
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                    {
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                "uniprot_canonical_ac": "Q8IXL6-1"
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                "start_pos": 478,
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                    {
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                    {
                        "database": "PubMed",
                        "id": "23754375",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/23754375"
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                    {
                        "database": "PubMed",
                        "id": "25789606",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/25789606"
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                    {
                        "database": "PubMed",
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                    {
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                "start_pos": 91,
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                "sequence_org": "LQD",
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                "start_pos": 24,
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                "sequence_org": "S",
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        "title": "Matrix metalloproteinases degrade insulin-like growth factor-binding protein-3 in dermal fibroblast cultures.",
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    {
        "title": "Recombinant human insulin-like growth factor (IGF)-binding protein-6 inhibits IGF-II-induced differentiation of L6A1 myoblasts.",
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        "authors": "Bach LA, Hsieh S, Brown AL, Rechler MM",
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    {
        "title": "Identification of insulin-like growth factor-binding protein-3 (IGFBP-3) fragments and IGFBP-5 proteolytic activity in human seminal plasma: a comparison of normal and vasectomized patients.",
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        "authors": "Lee KO, Oh Y, Giudice LC, Cohen P, Peehl DM, Rosenfeld RG",
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        "title": "Biological effects of prostate specific antigen as an insulin-like growth factor binding protein-3 protease.",
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    {
        "title": "Interactions between insulin-like growth factor-I (IGF-I) and the system of plasminogen activators and their inhibitors in the control of IGF-binding protein-3 production and proteolysis in human osteosarcoma cells.",
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        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                        "id": "Q14766",
                        "url": "https://www.uniprot.org/uniprotkb/Q14766"
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                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.7527330",
        "abstract": "",
        "glycosylation": [],
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        "phosphorylation": [],
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    {
        "title": "Biochemical analysis of prostate specific antigen-proteolyzed insulin-like growth factor binding protein-3.",
        "journal": "Growth regulation",
        "date": "1994",
        "authors": "Fielder PJ, Rosenfeld RG, Graves HC, Grandbois K, Maack CA, Sawamura S, Ogawa Y, Sommer A, Cohen P",
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    {
        "title": "Serum levels of insulin-like growth factor (IGF)-binding protein-3 (IGFBP-3) in healthy infants, children, and adolescents: the relation to IGF-I, IGF-II, IGFBP-1, IGFBP-2, age, sex, body mass index, and pubertal maturation.",
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    {
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        "title": "Binding of mutants of human insulin-like growth factor II to insulin-like growth factor binding proteins 1-6.",
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                "protein_name": "Latent-transforming growth factor beta-binding protein 1",
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                "tax_name": "Human"
            },
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                "protein_name": "Transmembrane protein 132A",
                "gene_name": "TMEM132A",
                "tax_name": "Human"
            },
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                "protein_name": "Prothrombin",
                "gene_name": "F2",
                "tax_name": "Human"
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                "protein_name": "Amelogenin, X isoform",
                "gene_name": "AMELX",
                "tax_name": "Human"
            },
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                "protein_name": "Fibrinogen alpha chain",
                "gene_name": "FGA",
                "tax_name": "Human"
            },
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                "protein_name": "Follistatin-related protein 1",
                "gene_name": "FSTL1",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "O95633-1",
                "protein_name": "Follistatin-related protein 3",
                "gene_name": "FSTL3",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "O14791-1",
                "protein_name": "Apolipoprotein L1",
                "gene_name": "APOL1",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q9HCE9-1",
                "protein_name": "Anoctamin-8",
                "gene_name": "ANO8",
                "tax_name": "Human"
            },
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                "protein_name": "Apolipoprotein B-100",
                "gene_name": "APOB",
                "tax_name": "Human"
            },
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                "protein_name": "Fibronectin",
                "gene_name": "FN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01008-1",
                "protein_name": "Antithrombin-III",
                "gene_name": "SERPINC1",
                "tax_name": "Human"
            },
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                "protein_name": "Amelotin",
                "gene_name": "AMTN",
                "tax_name": "Human"
            },
            {
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                "protein_name": "Proenkephalin-A",
                "gene_name": "PENK",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q02818-1",
                "protein_name": "Nucleobindin-1",
                "gene_name": "NUCB1",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q07065-1",
                "protein_name": "Cytoskeleton-associated protein 4",
                "gene_name": "CKAP4",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P02765-1",
                "protein_name": "Alpha-2-HS-glycoprotein",
                "gene_name": "AHSG",
                "tax_name": "Human"
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                "protein_name": "Fibrinogen gamma chain",
                "gene_name": "FGG",
                "tax_name": "Human"
            },
            {
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                "protein_name": "Protein disulfide-isomerase",
                "gene_name": "P4HB",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q14393-2",
                "protein_name": "Growth arrest-specific protein 6",
                "gene_name": "GAS6",
                "tax_name": "Human"
            },
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                "protein_name": "Glypican-3",
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                "tax_name": "Human"
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                "protein_name": "Golgi membrane protein 1",
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                "tax_name": "Human"
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                "protein_name": "Macrophage colony-stimulating factor 1",
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                "tax_name": "Human"
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                "protein_name": "Interleukin-6",
                "gene_name": "IL6",
                "tax_name": "Human"
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                "protein_name": "Palmitoleoyl-protein carboxylesterase NOTUM",
                "gene_name": "NOTUM",
                "tax_name": "Human"
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                "protein_name": "Interstitial collagenase",
                "gene_name": "MMP1",
                "tax_name": "Human"
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                "protein_name": "Mesothelin",
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                "tax_name": "Human"
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                "protein_name": "Pappalysin-1",
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                "tax_name": "Human"
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                "tax_name": "Human"
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                "protein_name": "Secretogranin-3",
                "gene_name": "SCG3",
                "tax_name": "Human"
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                "protein_name": "Metalloproteinase inhibitor 1",
                "gene_name": "TIMP1",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P17936-1",
                "protein_name": "Insulin-like growth factor-binding protein 3",
                "gene_name": "IGFBP3",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P02649-1",
                "protein_name": "Apolipoprotein E",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13521-1",
                "protein_name": "Secretogranin-2",
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                "tax_name": "Human"
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                "protein_name": "Cathepsin G",
                "gene_name": "CTSG",
                "tax_name": "Human"
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                "protein_name": "Ceruloplasmin",
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                "tax_name": "Human"
            },
            {
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                "protein_name": "Osteopontin",
                "gene_name": "SPP1",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P0C0L4-1",
                "protein_name": "Complement C4-A",
                "gene_name": "C4A",
                "tax_name": "Human"
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                "protein_name": "CCN family member 1",
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                "protein_name": "Kallikrein-2",
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                "tax_name": "Human"
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                "protein_name": "Laminin subunit beta-1",
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                "tax_name": "Human"
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                "protein_name": "Kallikrein-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9UKR3-1",
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                "tax_name": "Human"
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                "tax_name": "Human"
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                "protein_name": "Trans-Golgi network integral membrane protein 2",
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                "protein_name": "Inter-alpha-trypsin inhibitor heavy chain H2",
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                "tax_name": "Human"
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                "tax_name": "Human"
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            {
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            {
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            {
                "uniprot_canonical_ac": "P22692-1",
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            {
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            {
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                "protein_name": "Matrix extracellular phosphoglycoprotein",
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                "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A",
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            {
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            {
                "uniprot_canonical_ac": "P02771-1",
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                "tax_name": "Human"
            },
            {
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q6PCB0-1",
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            {
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    {
        "title": "Glucose does not influence the insulin-like growth factor (JGF) binding to carrier proteins (IGFBPs): analysis of rat and human serum by western ligand blotting.",
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    {
        "title": "Measurement of insulin-like growth factor (IGF)-II binding to purified IGF binding proteins 1-6: comparison of charcoal adsorption and high performance size exclusion chromatography.",
        "journal": "Biochimica et biophysica acta",
        "date": "1996",
        "authors": "Bach LA, Rechler MM",
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    {
        "title": "MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling.",
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        "title": "Mechanism of TGFbeta receptor inhibition by FKBP12.",
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    {
        "title": "The insulin-like growth factor (IGF)binding protein 1 binding epitope on IGF-I probed by heteronuclear NMR spectroscopy and mutational analysis.",
        "journal": "The Journal of biological chemistry",
        "date": "1998",
        "authors": "Jansson M, Andersson G, Uhlen M, Nilsson B, Kordel J",
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            "id": "9733769",
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        "title": "Elevated levels of the IGF-binding protein protease MMP-1 in asthmatic airway smooth muscle.",
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