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Biophys. Acta", "date": "2002", "authors": "Oldfield S, Lowry C, Ruddick J, Lightman S", "reference": { "type": "PubMed", "id": "12183068", "url": "https://pubmed.ncbi.nlm.nih.gov/12183068" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q91WA9-1", "protein_name": "ATP-binding cassette subfamily G member 4", "gene_name": "Abcg4", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZCM3-1", "protein_name": "ATP-binding cassette subfamily G member 4", "gene_name": "Abcg4", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q9H172-1", "protein_name": "ATP-binding cassette sub-family G member 4", "gene_name": "ABCG4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZY2-1", "protein_name": "Phospholipid-transporting ATPase ABCA7", "gene_name": "ABCA7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N139-1", "protein_name": "ATP-binding cassette sub-family A member 6", "gene_name": "ABCA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WWZ4-1", 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Cell Biol.", "date": "2000", "authors": "Alahari S K, Lee J W, Juliano R L", "reference": { "type": "PubMed", "id": "11121431", "url": "https://pubmed.ncbi.nlm.nih.gov/11121431" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P11688-1", "protein_name": "Integrin alpha-5", "gene_name": "Itga5", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q80TM9-1", "protein_name": "Nischarin", "gene_name": "Nisch", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11688", "url": "https://www.uniprot.org/uniprotkb/P11688" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.11121431", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A membrane proximal region of the integrin alpha5 subunit is important for its interaction with nischarin.", "journal": "Biochem. J.", "date": "2004", "authors": "Alahari Suresh K, Nasrallah Hani", "reference": { "type": "PubMed", "id": "14535848", "url": "https://pubmed.ncbi.nlm.nih.gov/14535848" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P11688-1", "protein_name": "Integrin alpha-5", "gene_name": "Itga5", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q80TM9-1", "protein_name": "Nischarin", "gene_name": "Nisch", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P11688", "url": "https://www.uniprot.org/uniprotkb/P11688" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.14535848", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ 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"authors": "Arva A, Kasu YAT, Duncan J, Alkhatatbeh MA, Brower CS", "reference": { "type": "PubMed", "id": "33443146", "url": "https://pubmed.ncbi.nlm.nih.gov/33443146" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q810M6-1", "protein_name": "Protein LIAT1", "gene_name": "Liat1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ERI5-1", "protein_name": "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "gene_name": "Jmjd6", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZQX7-1", "protein_name": "Protein LIAT1", "gene_name": "LIAT1", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q810M6", "url": "https://www.uniprot.org/uniprotkb/Q810M6" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "mutagenesis": [ { "start_pos": 277, "end_pos": 277, "sequence_org": "N", "sequence_mut": "A", "comment": "Loss of 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of Ly-6K as a novel marker for mouse plasma cells.", "journal": "Molecular immunology", "date": "2008", "authors": "von Allmen CE, Bauer M, Dietmeier K, Buser RB, Gwerder M, Muntwiler S, Utzinger S, Saudan P, Bachmann MF, Beerli RR", "reference": { "type": "PubMed", "id": "18372042", "url": "https://pubmed.ncbi.nlm.nih.gov/18372042" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CWP4", "url": "https://www.uniprot.org/uniprotkb/Q9CWP4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.18372042", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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Commun.", "date": "2008", "authors": "Yoshitake H, Tsukamoto H, Maruyama-Fukushima M, Takamori K, Ogawa H, Araki Y", "reference": { "type": "PubMed", "id": "18503752", "url": "https://pubmed.ncbi.nlm.nih.gov/18503752" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JMI7-1", "protein_name": "Testis-expressed protein 101", "gene_name": "Tex101", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CWP4", "url": "https://www.uniprot.org/uniprotkb/Q9CWP4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.18503752", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular expression of Ly6k, a putative glycosylphosphatidyl-inositol-anchored membrane protein on the mouse testicular germ cells.", "journal": "Biochem. 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Rep.", "date": "2016", "authors": "Endo S, Yoshitake H, Tsukamoto H, Matsuura H, Kato K, Sakuraba M, Takamori K, Fujiwara H, Takeda S, Araki Y", "reference": { "type": "PubMed", "id": "27005865", "url": "https://pubmed.ncbi.nlm.nih.gov/27005865" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JMI7-1", "protein_name": "Testis-expressed protein 101", "gene_name": "Tex101", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9CWP4", "url": "https://www.uniprot.org/uniprotkb/Q9CWP4" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.27005865", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, 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Androl.", "date": "2013", "authors": "Wei J, Li SJ, Shi H, Wang HY, Rong CT, Zhu P, Jin SH, Liu J, Li JY", "reference": { "type": "PubMed", "id": "24013621", "url": "https://pubmed.ncbi.nlm.nih.gov/24013621" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9D925-1", "protein_name": "Lysozyme-like protein 4", "gene_name": "Lyzl4", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DA11-1", "protein_name": "Lysozyme-like protein 6", "gene_name": "Lyzl6", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O75951-1", "protein_name": "Lysozyme-like protein 6", "gene_name": "LYZL6", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q9D925", "url": "https://www.uniprot.org/uniprotkb/Q9D925" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.24013621", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": 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No effect on AP-1 activity or activation of CHUK and IKBKB. Loss of binding to IKBKB.", "evidence": [ { "database": "UniProtKB", "id": "P53349", "url": "https://www.uniprot.org/uniprotkb/P53349" }, { "database": "PubMed", "id": "14500727", "url": "https://pubmed.ncbi.nlm.nih.gov/14500727" } ], "uniprot_canonical_ac": "P53349-1" }, { "start_pos": 1396, "end_pos": 1396, "sequence_org": "F", "sequence_mut": "A", "comment": "Loss of AP-1 and NF-kappa-B transcription factor activity. Reduced ability to activate MAP2K1, MAP2K4, MAP2K7, CHUK and IKBKB.", "evidence": [ { "database": "UniProtKB", "id": "P53349", "url": "https://www.uniprot.org/uniprotkb/P53349" }, { "database": "PubMed", "id": "14500727", "url": "https://pubmed.ncbi.nlm.nih.gov/14500727" } ], "uniprot_canonical_ac": "P53349-1" }, { "start_pos": 1397, "end_pos": 1397, "sequence_org": "M", "sequence_mut": "A", "comment": "Loss of AP-1 and NF-kappa-B transcription factor activity. 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"1993", "authors": "Lange-Carter CA, Pleiman CM, Gardner AM, Blumer KJ, Johnson GL", "reference": { "type": "PubMed", "id": "8385802", "url": "https://pubmed.ncbi.nlm.nih.gov/8385802" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P53349-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 1", "gene_name": "Map3k1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P31938-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "Map2k1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P53349", "url": "https://www.uniprot.org/uniprotkb/P53349" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.8385802", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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Chem.", "date": "1987", "authors": "Bagchi S, Wise L S, Brown M L, Bregman D, Sul H S, Rubin C S", "reference": { "type": "PubMed", "id": "3805042", "url": "https://pubmed.ncbi.nlm.nih.gov/3805042" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P06801-1", "protein_name": "NADP-dependent malic enzyme", "gene_name": "Me1", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P06801", "url": "https://www.uniprot.org/uniprotkb/P06801" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.3805042", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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T O, Griffin J W, Tu P h, Lee V M, Li C, Roder J, Trapp B D", "reference": { "type": "PubMed", "id": "9482781", "url": "https://pubmed.ncbi.nlm.nih.gov/9482781" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P20917-1", "protein_name": "Myelin-associated glycoprotein", "gene_name": "Mag", "tax_name": "Mouse" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "P20917", "url": "https://www.uniprot.org/uniprotkb/P20917" } ], "common_name": "Mouse", "glygen_name": "Mouse", "reference_species": "Mus musculus [10090]" } ], "record_id": "pubmed.9482781", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { 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"title": "Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases.", "journal": "eLife", "date": "2016", "authors": "Steger M, Tonelli F, Ito G, Davies P, Trost M, Vetter M, Wachter S, Lorentzen E, Duddy G, Wilson S, Baptista MA, Fiske BK, Fell MJ, Morrow JA, Reith AD, Alessi DR, Mann M", "reference": { "type": "PubMed", "id": "26824392", "url": "https://pubmed.ncbi.nlm.nih.gov/26824392" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q5S006-1", "protein_name": "Leucine-rich repeat serine/threonine-protein kinase 2", "gene_name": "Lrrk2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P61006-1", "protein_name": "Ras-related protein Rab-8A", "gene_name": "RAB8A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61026-1", "protein_name": "Ras-related protein Rab-10", "gene_name": "RAB10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IQ22-1", "protein_name": "Ras-related protein Rab-12", "gene_name": "RAB12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96QF0-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "RAB3IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35283-1", "protein_name": "Ras-related protein Rab-12", "gene_name": "Rab12", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P20336-1", "protein_name": "Ras-related protein Rab-3A", "gene_name": "RAB3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55258-1", "protein_name": "Ras-related protein Rab-8A", "gene_name": "Rab8a", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P61027-1", "protein_name": "Ras-related protein Rab-10", "gene_name": "Rab10", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q5S007-1", "protein_name": "Leucine-rich repeat serine/threonine-protein kinase 2", "gene_name": "LRRK2", "tax_name": "Human" } ], "species": [ { "name": "Mus musculus", "taxid": 10090, "evidence": [ { "database": "UniProtKB", "id": "Q5S006", "url": "https://www.uniprot.org/uniprotkb/Q5S006" } 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Does not translocate to LRRK2-positive lysosomes and does not suppress lysosomal enlargement.", "evidence": [ { "database": "UniProtKB", "id": "P61006", "url": "https://www.uniprot.org/uniprotkb/P61006" }, { "database": "PubMed", "id": "29125462", "url": "https://pubmed.ncbi.nlm.nih.gov/29125462" }, { "database": "PubMed", "id": "30398148", "url": "https://pubmed.ncbi.nlm.nih.gov/30398148" }, { "database": "PubMed", "id": "26824392", "url": "https://pubmed.ncbi.nlm.nih.gov/26824392" }, { "database": "PubMed", "id": "30209220", "url": "https://pubmed.ncbi.nlm.nih.gov/30209220" } ], "uniprot_canonical_ac": "P61006-1" }, { "start_pos": 72, "end_pos": 72, "sequence_org": "T", "sequence_mut": "E", "comment": "Phosphomimetic mutant. No effect on the binding of GDP or GTP. Loss of GDI1, GDI2, CHM, CHML, RABGGTA, RABGGTB, RAB3IP, TBC1D15, and INPP5B binding. Increases localization to the cell membrane.", "evidence": [ { "database": "UniProtKB", "id": "P61006", "url": "https://www.uniprot.org/uniprotkb/P61006" }, { "database": "PubMed", "id": "29125462", "url": "https://pubmed.ncbi.nlm.nih.gov/29125462" }, { "database": "PubMed", "id": "30398148", "url": "https://pubmed.ncbi.nlm.nih.gov/30398148" }, { "database": "PubMed", "id": "26824392", "url": "https://pubmed.ncbi.nlm.nih.gov/26824392" }, { "database": "PubMed", "id": "30209220", "url": "https://pubmed.ncbi.nlm.nih.gov/30209220" } ], "uniprot_canonical_ac": "P61006-1" }, { "start_pos": 73, "end_pos": 73, "sequence_org": "T", "sequence_mut": "A", "comment": "Loss of phosphorylation. No effect on GDI1 and GDI2 binding. Increases localization to the cytosol. Does not translocate to LRRK2-positive lysosomes and does not promote lysosomal content release.", "evidence": [ { "database": "UniProtKB", "id": "P61026", "url": "https://www.uniprot.org/uniprotkb/P61026" }, { "database": "PubMed", "id": "29125462", "url": "https://pubmed.ncbi.nlm.nih.gov/29125462" }, { "database": "PubMed", "id": "30398148", "url": "https://pubmed.ncbi.nlm.nih.gov/30398148" }, { "database": "PubMed", "id": "26824392", "url": "https://pubmed.ncbi.nlm.nih.gov/26824392" }, { "database": "PubMed", "id": "30209220", "url": "https://pubmed.ncbi.nlm.nih.gov/30209220" } ], "uniprot_canonical_ac": "P61026-1" }, { "start_pos": 73, "end_pos": 73, "sequence_org": "T", "sequence_mut": "E", "comment": "Phosphomimetic mutant. Loss of GDI1 and GDI2 binding. Increases localization to the Golgi complex.", "evidence": [ { "database": "UniProtKB", "id": "P61026", "url": "https://www.uniprot.org/uniprotkb/P61026" }, { "database": "PubMed", "id": "29125462", "url": "https://pubmed.ncbi.nlm.nih.gov/29125462" }, { "database": "PubMed", "id": "30398148", "url": "https://pubmed.ncbi.nlm.nih.gov/30398148" }, { "database": "PubMed", "id": "26824392", "url": "https://pubmed.ncbi.nlm.nih.gov/26824392" }, { "database": "PubMed", "id": "30209220", "url": "https://pubmed.ncbi.nlm.nih.gov/30209220" } ], "uniprot_canonical_ac": "P61026-1" }, { "start_pos": 106, "end_pos": 106, "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of phosphorylation. 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No loss of interaction with SEC16A and no loss of ability to recruit SEC16A to endoplasmic reticulum exit sites. 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