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protein, aggregates during apoptosis of human promyelocytic leukemia HL-60 cells.", "journal": "J. Biol. Chem.", "date": "1999", "authors": "Masumoto J, Taniguchi S, Ayukawa K, Sarvotham H, Kishino T, Niikawa N, Hidaka E, Katsuyama T, Higuchi T, Sagara J", "reference": { "type": "PubMed", "id": "10567338", "url": "https://pubmed.ncbi.nlm.nih.gov/10567338" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10567338", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Activation of a caspase-9-mediated apoptotic pathway by subcellular redistribution of the novel caspase recruitment domain protein TMS1.", "journal": "Cancer research", "date": "2000", "authors": "McConnell BB, Vertino PM", "reference": { "type": "PubMed", "id": "11103777", "url": "https://pubmed.ncbi.nlm.nih.gov/11103777" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Nucleotide receptors: an emerging family of regulatory molecules in blood cells.", "journal": "Blood", "date": "2001", "authors": "Di Virgilio F, Chiozzi P, Ferrari D, Falzoni S, Sanz JM, Morelli A, Torboli M, Bolognesi G, Baricordi 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Biophys. Res. Commun.", "date": "2001", "authors": "Geddes B J, Wang L, Huang W J, Lavellee M, Manji G A, Brown M, Jurman M, Cao J, Morgenstern J, Merriam S, Glucksmann M A, DiStefano P S, Bertin J", "reference": { "type": "PubMed", "id": "11374873", "url": "https://pubmed.ncbi.nlm.nih.gov/11374873" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPP4-1", "protein_name": "NLR family CARD domain-containing protein 4", "gene_name": "NLRC4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11374873", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interaction between pyrin and the apoptotic speck protein (ASC) modulates ASC-induced apoptosis.", "journal": "J. Biol. Chem.", "date": "2001", "authors": "Richards N, Schaner P, Diaz A, Stuckey J, Shelden E, Wadhwa A, Gumucio DL", "reference": { "type": "PubMed", "id": "11498534", "url": "https://pubmed.ncbi.nlm.nih.gov/11498534" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15553-2", "protein_name": "Pyrin", "gene_name": "MEFV", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09601-1", "protein_name": "Heme oxygenase 1", "gene_name": "HMOX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43586-1", "protein_name": "Proline-serine-threonine 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Biol. Chem.", "date": "2002", "authors": "Manji GA, Wang L, Geddes BJ, Brown M, Merriam S, Al-Garawi A, Mak S, Lora JM, Briskin M, Jurman M, Cao J, DiStefano PS, Bertin J", "reference": { "type": "PubMed", "id": "11786556", "url": "https://pubmed.ncbi.nlm.nih.gov/11786556" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15553-2", "protein_name": "Pyrin", "gene_name": "MEFV", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09601-1", "protein_name": "Heme oxygenase 1", "gene_name": "HMOX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXC3-1", 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Biol. 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Cell", "date": "2002", "authors": "Martinon F, Burns K, Tschopp J", "reference": { "type": "PubMed", "id": "12191486", "url": "https://pubmed.ncbi.nlm.nih.gov/12191486" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15553-2", "protein_name": "Pyrin", "gene_name": "MEFV", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09601-1", "protein_name": "Heme oxygenase 1", "gene_name": "HMOX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43586-1", "protein_name": "Proline-serine-threonine phosphatase-interacting protein 1", "gene_name": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Pyrin binds the PSTPIP1/CD2BP1 protein, defining familial Mediterranean fever and PAPA syndrome as disorders in the same pathway.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2003", "authors": "Shoham NG, Centola M, Mansfield E, Hull KM, Wood G, Wise CA, Kastner DL", "reference": { "type": "PubMed", "id": "14595024", "url": "https://pubmed.ncbi.nlm.nih.gov/14595024" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15553-2", "protein_name": "Pyrin", "gene_name": "MEFV", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09601-1", "protein_name": "Heme oxygenase 1", "gene_name": "HMOX1", "tax_name": "Human" }, { 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Immunol.", "date": "2003", "authors": "Stehlik Christian, Lee Sug Hyung, Dorfleutner Andrea, Stassinopoulos Angela, Sagara Junji, Reed John C", "reference": { "type": "PubMed", "id": "14634131", "url": "https://pubmed.ncbi.nlm.nih.gov/14634131" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14634131", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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bid-dependent apoptosis in type II cells.", "journal": "Oncogene", "date": "2007-03-15", "authors": "Hasegawa M, Kawase K, Inohara N, Imamura R, Yeh W-C, Kinoshita T, Suda T", "reference": { "type": "PubMed", "id": "16964285", "url": "https://pubmed.ncbi.nlm.nih.gov/16964285" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16964285", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } 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Immun.", "date": "2007", "authors": "Dorfleutner Andrea, Bryan Nicole B, Talbott Siera J, Funya Kristin N, Rellick Stephanie L, Reed John C, Shi Xianglin, Rojanasakul Yon, Flynn Daniel C, Stehlik Christian", "reference": { "type": "PubMed", "id": "17178784", "url": "https://pubmed.ncbi.nlm.nih.gov/17178784" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXC3-1", "protein_name": "Pyrin domain-containing protein 1", "gene_name": "PYDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q56P42-1", "protein_name": "Pyrin domain-containing protein 2", "gene_name": "PYDC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NX02-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 2", "gene_name": "NLRP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17178784", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Pyrin-only protein 2 modulates NF-kappaB and disrupts ASC:CLR interactions.", "journal": "J. 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "A role for mitochondria in NLRP3 inflammasome activation.", "journal": "Nature", "date": "2011", "authors": "Zhou Rongbin, Yazdi Amir S, Menu Philippe, Tschopp J\u00fcrg", "reference": { "type": "PubMed", "id": "21124315", "url": "https://pubmed.ncbi.nlm.nih.gov/21124315" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21124315", "abstract": 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Holley-Guthrie Elizabeth A, Huang Max Tze-Han, Moore Chris B, Bergstralh Daniel T, Allen Irving C, Lei Yu, Gris Denis, Ting Jenny Pan-Yun", "reference": { "type": "PubMed", "id": "21487011", "url": "https://pubmed.ncbi.nlm.nih.gov/21487011" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21487011", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15553-2", "protein_name": "Pyrin", "gene_name": "MEFV", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09601-1", "protein_name": "Heme oxygenase 1", "gene_name": "HMOX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43586-1", "protein_name": "Proline-serine-threonine phosphatase-interacting protein 1", "gene_name": "PSTPIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10599-1", "protein_name": "Thioredoxin", "gene_name": "TXN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2Z0-1", "protein_name": "Protein SGT1 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[] } ] }, { "title": "Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1beta via a noncanonical caspase-8 inflammasome.", "journal": "Nature immunology", "date": "2012", "authors": "Gringhuis SI, Kaptein TM, Wevers BA, Theelen B, van der Vlist M, Boekhout T, Geijtenbeek TB", "reference": { "type": "PubMed", "id": "22267217", "url": "https://pubmed.ncbi.nlm.nih.gov/22267217" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01584-1", "protein_name": "Interleukin-1 beta", "gene_name": "IL1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UDY8-1", "protein_name": "Mucosa-associated lymphoid tissue lymphoma translocation 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a viral recognition pathway used by the host to signal inflammasome activation.", "journal": "Thorax", "date": "2013", "authors": "Triantafilou Kathy, Kar Satwik, Vakakis Emmanouil, Kotecha Sailesh, Triantafilou Martha", "reference": { "type": "PubMed", "id": "23229815", "url": "https://pubmed.ncbi.nlm.nih.gov/23229815" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23229815", "abstract": "", 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Med.", "date": "2013", "authors": "Jourdan Tony, Godlewski Grzegorz, Cinar Resat, Bertola Adeline, Szanda Gerg\u0151, Liu Jie, Tam Joseph, Han Tiffany, Mukhopadhyay Bani, Skarulis Monica C, Ju Cynthia, Aouadi Myriam, Czech Michael P, Kunos George", "reference": { "type": "PubMed", "id": "23955712", "url": "https://pubmed.ncbi.nlm.nih.gov/23955712" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20272-1", "protein_name": "Cannabinoid receptor 1", "gene_name": "Cnr1", "tax_name": "Rat" }, { "uniprot_canonical_ac": "P14844-1", "protein_name": "C-C motif chemokine 2", "gene_name": "Ccl2", "tax_name": "Rat" }, { "uniprot_canonical_ac": "P01584-1", "protein_name": "Interleukin-1 beta", "gene_name": "IL1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20607-1", "protein_name": "Interleukin-6", 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0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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Biol. Chem.", "date": "2016", "authors": "Oroz Javier, Barrera-Vilarmau Susana, Alfonso Carlos, Rivas Germ\u00e1n, de Alba Eva", "reference": { "type": "PubMed", "id": "27432880", "url": "https://pubmed.ncbi.nlm.nih.gov/27432880" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27432880", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The deubiquitinating enzyme, ubiquitin-specific peptidase 50, regulates inflammasome activation by targeting the ASC adaptor protein.", "journal": "FEBS letters", "date": "2017", "authors": "Lee JY, Seo D, You J, Chung S, Park JS, Lee JH, Jung SM, Lee YS, Park SH", "reference": { "type": "PubMed", "id": "28094437", "url": "https://pubmed.ncbi.nlm.nih.gov/28094437" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P8X6-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 50", "gene_name": "Usp50", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q70EL3-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 50", "gene_name": "USP50", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 327, "end_pos": 327, "sequence_org": "H", "sequence_mut": "A", "comment": "Does not affect ubiquitin-like protein peptidase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q70EL3", "url": "https://www.uniprot.org/uniprotkb/Q70EL3" }, { "database": "PubMed", "id": "28094437", "url": "https://pubmed.ncbi.nlm.nih.gov/28094437" } ], "uniprot_canonical_ac": "Q70EL3-1" }, { "start_pos": 53, "end_pos": 53, "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes ubiquitin-like protein peptidase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q70EL3", "url": "https://www.uniprot.org/uniprotkb/Q70EL3" }, { "database": "PubMed", "id": "28094437", "url": "https://pubmed.ncbi.nlm.nih.gov/28094437" }, { "database": "PubMed", "id": "36876523", "url": "https://pubmed.ncbi.nlm.nih.gov/36876523" } ], "uniprot_canonical_ac": "Q70EL3-1" } ], "record_id": "pubmed.28094437", "abstract": "", "glycosylation": [], "snv": [], 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}, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Inflammasome Activation Triggers Caspase-1-Mediated Cleavage of cGAS to Regulate Responses to DNA Virus Infection.", "journal": "Immunity", "date": "2017", "authors": "Wang Y, Ning X, Gao P, Wu S, Sha M, Lv M, Zhou X, Gao J, Fang R, Meng G, Su X, Jiang Z", "reference": { "type": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P70343-1", "protein_name": "Caspase-4", "gene_name": "Casp4", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPB4-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "Pycard", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P29452-1", "protein_name": "Caspase-1", "gene_name": "Casp1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P49662-1", "protein_name": "Caspase-4", "gene_name": "CASP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51878-1", "protein_name": "Caspase-5", "gene_name": "CASP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8C6L5-1", "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "Cgas", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N884-1", "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "CGAS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9ULZ3", "url": "https://www.uniprot.org/uniprotkb/Q9ULZ3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 254, "end_pos": 254, "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of catalytic activity and of autocatalytic processing. Loss of LPS-induced pyroptosis. No effect on the interaction with LPS.", "evidence": [ { "database": "UniProtKB", "id": "P70343", "url": "https://www.uniprot.org/uniprotkb/P70343" }, { "database": "PubMed", "id": "22002608", "url": "https://pubmed.ncbi.nlm.nih.gov/22002608" }, { "database": "PubMed", "id": "25119034", "url": "https://pubmed.ncbi.nlm.nih.gov/25119034" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" }, { "database": "PubMed", "id": "30135078", "url": "https://pubmed.ncbi.nlm.nih.gov/30135078" }, { "database": "PubMed", "id": "30392956", "url": "https://pubmed.ncbi.nlm.nih.gov/30392956" } ], "uniprot_canonical_ac": "P70343-1" }, { "start_pos": 258, "end_pos": 258, "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of enzymatic activity. Loss of LPS-induced pyroptosis. No effect on the interaction with LPS. Decrease in cell death induced by TMEM214 overexpression. Does not support IL1B and IL18 secretion following UVB irradiation.", "evidence": [ { "database": "UniProtKB", "id": "P49662", "url": "https://www.uniprot.org/uniprotkb/P49662" }, { "database": "PubMed", "id": "22246630", "url": "https://pubmed.ncbi.nlm.nih.gov/22246630" }, { "database": "PubMed", "id": "25119034", "url": "https://pubmed.ncbi.nlm.nih.gov/25119034" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" }, { "database": "PubMed", "id": "23661706", "url": "https://pubmed.ncbi.nlm.nih.gov/23661706" }, { "database": "PubMed", "id": "37993712", "url": "https://pubmed.ncbi.nlm.nih.gov/37993712" }, { "database": "PubMed", "id": "37993714", "url": "https://pubmed.ncbi.nlm.nih.gov/37993714" } ], "uniprot_canonical_ac": "P49662-1" }, { "start_pos": 315, "end_pos": 315, "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes protease activity.", "evidence": [ { "database": "UniProtKB", "id": "P51878", "url": "https://www.uniprot.org/uniprotkb/P51878" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "P51878-1" }, { "start_pos": 140, "end_pos": 140, "sequence_org": "D", "sequence_mut": "A", "comment": "Highly decreases cleavage by CASP1 and enhances type IIFN and RSAD2 induction upon DNA virus infection. Abolishes cleavage by CASP1, enhances RSAD2 induction upon DNA virus infection but no effect on cleavage by CASP5; when associated with A-157. Highly decreases cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-33; A-67; A-90 and A-95. Abolishes cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-33; A-67; A-90; A-95 and A-157.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "Q8N884-1" }, { "start_pos": 140, "end_pos": 140, "sequence_org": "D", "sequence_mut": "H", "comment": "Highly decreases cleavage by CASP1 and enhances type IIFN and RSAD2 induction upon DNA virus infection.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "Q8N884-1" }, { "start_pos": 157, "end_pos": 157, "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on type IIFN and RSAD2 induction. Highly decreases cleavage by CASP1 and enhances type IIFN and enhances RSAD2 induction upon DNA virus infection. Abolishes cleavage by CASP1, enhances RSAD2 induction upon DNA virus infection but no effect on cleavage by CASP5; when associated with A-140. Abolishes cleavage by CASP1; when associated with A-33; A-67; A-90; A-95 and A-140.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "Q8N884-1" }, { "start_pos": 157, "end_pos": 157, "sequence_org": "D", "sequence_mut": "H", "comment": "Highly decreases cleavage by CASP1 and enhances type IIFN and enhances RSAD2 induction upon DNA virus infection.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "Q8N884-1" }, { "start_pos": 33, "end_pos": 33, "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on type IIFN and RSAD2 induction. No effect on cleavage by CASP1. No effect on cleavage by CASP1; when associated with A-67; A-90 and A-95. Highly decreases cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-67; A-90; A-95 and A-140. Abolishes cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-67; A-90; A-95; A-140 and A-157.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "Q8N884-1" }, { "start_pos": 67, "end_pos": 67, "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on type IIFN and RSAD2 induction. No effect on cleavage by CASP1; when associated with A-33; A-90 and A-95. Highly decreases cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-33; A-90; A-95 and A-140. Abolishes cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-33; A-90; A-95; A-140 and A-157.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "Q8N884-1" }, { "start_pos": 90, "end_pos": 90, "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on type IIFN and RSAD2 induction. No effect on cleavage by CASP1; when associated with A-33; A-67 and A-95. Highly decreases cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-33; A-67; A-95 and A-140. Abolishes cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-33; A-67; A-95; A-140 and A-157.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "Q8N884-1" }, { "start_pos": 95, "end_pos": 95, "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on type IIFN and RSAD2 induction. No effect on cleavage by CASP1; when associated with A-33; A-67 and A-90. Highly decreases cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-33; A-67; A-90 and A-140. Abolishes cleavage by CASP1 and enhances RSAD2 induction upon DNA virus infection; when associated with A-33; A-67; A-90; A-140 and A-157.", "evidence": [ { "database": "UniProtKB", "id": "Q8N884", "url": "https://www.uniprot.org/uniprotkb/Q8N884" }, { "database": "PubMed", "id": "28314590", "url": "https://pubmed.ncbi.nlm.nih.gov/28314590" } ], "uniprot_canonical_ac": "Q8N884-1" } ], "record_id": "pubmed.28314590", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hsp90 inhibition as a means to inhibit activation of the NLRP3 inflammasome.", "journal": "Scientific reports", "date": "2018", "authors": "Piippo N, Korhonen E, Hytti M, Skottman H, Kinnunen K, Josifovska N, Petrovski G, Kaarniranta K, Kauppinen A", "reference": { "type": "PubMed", "id": "29712950", "url": "https://pubmed.ncbi.nlm.nih.gov/29712950" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15553-2", "protein_name": "Pyrin", "gene_name": "MEFV", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", 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