[
    {
        "title": "Reduction in cyclin D1/Cdk4/retinoblastoma protein signaling by CRE-decoy oligonucleotide.",
        "journal": "Biochemical and biophysical research communications",
        "date": "2001",
        "authors": "Park YG, Park S, Lim SO, Lee MS, Ryu CK, Kim I, Cho-Chung YS",
        "reference": {
            "type": "PubMed",
            "id": "11243864",
            "url": "https://pubmed.ncbi.nlm.nih.gov/11243864"
        },
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                "protein_name": "RAC-gamma serine/threonine-protein kinase",
                "gene_name": "AKT3",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P28482-1",
                "protein_name": "Mitogen-activated protein kinase 1",
                "gene_name": "MAPK1",
                "tax_name": "Human"
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                "protein_name": "Amphiregulin",
                "gene_name": "AREG",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P11831-1",
                "protein_name": "Serum response factor",
                "gene_name": "SRF",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q8TAS1-1",
                "protein_name": "Serine/threonine-protein kinase Kist",
                "gene_name": "UHMK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05397-1",
                "protein_name": "Focal adhesion kinase 1",
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            },
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                "protein_name": "Protransforming growth factor alpha",
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            },
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                "gene_name": "AKT2",
                "tax_name": "Human"
            },
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                "protein_name": "G1/S-specific cyclin-D1",
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                "protein_name": "Probetacellulin",
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                "tax_name": "Human"
            },
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                "gene_name": "MAPK3",
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            },
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                "uniprot_canonical_ac": "Q99075-1",
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                "uniprot_canonical_ac": "O14944-1",
                "protein_name": "Proepiregulin",
                "gene_name": "EREG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01100-1",
                "protein_name": "Protein c-Fos",
                "gene_name": "FOS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P00533-1",
                "protein_name": "Epidermal growth factor receptor",
                "gene_name": "EGFR",
                "tax_name": "Human"
            }
        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                        "database": "UniProtKB",
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                "glygen_name": "Human",
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        "abstract": "",
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            {
                "table_id": "glycosylation_automatic_literature_mining",
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    {
        "title": "Disabled-2 colocalizes with the LDLR in clathrin-coated pits and interacts with AP-2.",
        "journal": "Traffic (Copenhagen, Denmark)",
        "date": "2001",
        "authors": "Morris SM, Cooper JA",
        "reference": {
            "type": "PubMed",
            "id": "11247302",
            "url": "https://pubmed.ncbi.nlm.nih.gov/11247302"
        },
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                "protein_name": "Pro-epidermal growth factor",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q8NFH8-1",
                "protein_name": "RalBP1-associated Eps domain-containing protein 2",
                "gene_name": "REPS2",
                "tax_name": "Human"
            },
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                "protein_name": "Synaptotagmin-8",
                "gene_name": "SYT8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N9I0-1",
                "protein_name": "Synaptotagmin-2",
                "gene_name": "SYT2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86SS6-1",
                "protein_name": "Synaptotagmin-9",
                "gene_name": "SYT9",
                "tax_name": "Human"
            },
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                "protein_name": "Vesicle-associated membrane protein 7",
                "gene_name": "VAMP7",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P52594-1",
                "protein_name": "Arf-GAP domain and FG repeat-containing protein 1",
                "gene_name": "AGFG1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT88-1",
                "protein_name": "Synaptotagmin-11",
                "gene_name": "SYT11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60641-1",
                "protein_name": "Clathrin coat assembly protein AP180",
                "gene_name": "SNAP91",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15514-1",
                "protein_name": "Amphiregulin",
                "gene_name": "AREG",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P25098-1",
                "protein_name": "G protein-coupled receptor kinase 2",
                "gene_name": "GRK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95782-1",
                "protein_name": "AP-2 complex subunit alpha-1",
                "gene_name": "AP2A1",
                "tax_name": "Human"
            },
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                "protein_name": "Apolipoprotein B-100",
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            },
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                "protein_name": "COP9 signalosome complex subunit 3",
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                "tax_name": "Human"
            },
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            },
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                "protein_name": "Clathrin heavy chain 2",
                "gene_name": "CLTCL1",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P98078-1",
                "protein_name": "Disabled homolog 2",
                "gene_name": "Dab2",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "P17427-1",
                "protein_name": "AP-2 complex subunit alpha-2",
                "gene_name": "Ap2a2",
                "tax_name": "Mouse"
            },
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                "uniprot_canonical_ac": "A2ARV4-1",
                "protein_name": "Low-density lipoprotein receptor-related protein 2",
                "gene_name": "Lrp2",
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                "protein_name": "Segment polarity protein dishevelled homolog DVL-2",
                "gene_name": "DVL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35626-1",
                "protein_name": "G protein-coupled receptor kinase 3",
                "gene_name": "GRK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5SW96-1",
                "protein_name": "Low density lipoprotein receptor adapter protein 1",
                "gene_name": "LDLRAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01130-1",
                "protein_name": "Low-density lipoprotein receptor",
                "gene_name": "LDLR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CW1-1",
                "protein_name": "AP-2 complex subunit mu",
                "gene_name": "AP2M1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02786-1",
                "protein_name": "Transferrin receptor protein 1",
                "gene_name": "TFRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9ULV1-1",
                "protein_name": "Frizzled-4",
                "gene_name": "FZD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02787-1",
                "protein_name": "Serotransferrin",
                "gene_name": "TF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41221-1",
                "protein_name": "Protein Wnt-5a",
                "gene_name": "WNT5A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
                "protein_name": "COP9 signalosome complex subunit 5",
                "gene_name": "COPS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21579-1",
                "protein_name": "Synaptotagmin-1",
                "gene_name": "SYT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09496-1",
                "protein_name": "Clathrin light chain A",
                "gene_name": "CLTA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14108-1",
                "protein_name": "Lysosome membrane protein 2",
                "gene_name": "SCARB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35951-1",
                "protein_name": "Low-density lipoprotein receptor",
                "gene_name": "Ldlr",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "O14657-1",
                "protein_name": "Torsin-1B",
                "gene_name": "TOR1B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35070-1",
                "protein_name": "Probetacellulin",
                "gene_name": "BTC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15811-1",
                "protein_name": "Intersectin-1",
                "gene_name": "ITSN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01730-1",
                "protein_name": "T-cell surface glycoprotein CD4",
                "gene_name": "CD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09497-1",
                "protein_name": "Clathrin light chain B",
                "gene_name": "CLTB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I3-2",
                "protein_name": "Epsin-1",
                "gene_name": "EPN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0JRZ9-1",
                "protein_name": "F-BAR domain only protein 2",
                "gene_name": "FCHO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42566-1",
                "protein_name": "Epidermal growth factor receptor substrate 15",
                "gene_name": "EPS15",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O95208-1",
                "protein_name": "Epsin-2",
                "gene_name": "EPN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXE9-1",
                "protein_name": "Stonin-2",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P11717-1",
                "protein_name": "Cation-independent mannose-6-phosphate receptor",
                "gene_name": "IGF2R",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9NY64-1",
                "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q99075-1",
                "protein_name": "Proheparin-binding EGF-like growth factor",
                "gene_name": "HBEGF",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P20645-1",
                "protein_name": "Cation-dependent mannose-6-phosphate receptor",
                "gene_name": "M6PR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVZ3-1",
                "protein_name": "Adaptin ear-binding coat-associated protein 2",
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            {
                "uniprot_canonical_ac": "Q8NC96-1",
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            {
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                "protein_name": "Epigen",
                "gene_name": "EPGN",
                "tax_name": "Human"
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            {
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                "protein_name": "Proepiregulin",
                "gene_name": "EREG",
                "tax_name": "Human"
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            {
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                "protein_name": "Amyloid-beta precursor protein",
                "gene_name": "App",
                "tax_name": "Mouse"
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            {
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                "protein_name": "AP-2 complex subunit sigma",
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                "tax_name": "Human"
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            {
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            },
            {
                "uniprot_canonical_ac": "P00533-1",
                "protein_name": "Epidermal growth factor receptor",
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                "tax_name": "Human"
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            {
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                "protein_name": "Ubiquilin-1",
                "gene_name": "UBQLN1",
                "tax_name": "Human"
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            {
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                "protein_name": "E3 ubiquitin-protein ligase CBL",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O14964-1",
                "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate",
                "gene_name": "HGS",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P0CG48-1",
                "protein_name": "Polyubiquitin-C",
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                "tax_name": "Human"
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            {
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                "protein_name": "Signal transducing adapter molecule 2",
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            {
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                "protein_name": "Muscarinic acetylcholine receptor M2",
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                "tax_name": "Human"
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q2M2I8-1",
                "protein_name": "AP2-associated protein kinase 1",
                "gene_name": "AAK1",
                "tax_name": "Human"
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            {
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                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1",
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        ],
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                ],
                "common_name": "Human",
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                "reference_species": "Homo sapiens [9606]"
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        ],
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            {
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            {
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            {
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                ],
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            {
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                ],
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            {
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                "comment": "Greatly promotes interaction with DAB2.",
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                "comment": "Greatly impairs interaction with DAB2.",
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                ],
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            {
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                "sequence_org": "Y",
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                "comment": "No MAPK8IP1 nor APBA1 nor APBB1 nor DAB1 binding.",
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                ],
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            {
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                "comment": "Greatly impairs interaction with DAB2.",
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                ],
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                "comment": "Impairs interaction with DAB2.",
                "evidence": [
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                ],
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            {
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                "comment": "Greatly impairs interaction with DAB2.",
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                ],
                "uniprot_canonical_ac": "P12023-1"
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            {
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                "sequence_org": "Y",
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                "comment": "Impairs interaction with DAB2.",
                "evidence": [
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                ],
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                "sequence_org": "N",
                "sequence_mut": "A",
                "comment": "No MAPK8IP1 nor APBA1 nor Dab1 binding. No effect on APBB1 binding.",
                "evidence": [
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                    {
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                ],
                "uniprot_canonical_ac": "P12023-1"
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            {
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                "sequence_org": "N",
                "sequence_mut": "G",
                "comment": "Greatly impairs interaction with DAB2.",
                "evidence": [
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                ],
                "uniprot_canonical_ac": "P12023-1"
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            {
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                "sequence_org": "N",
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                "comment": "Greatly impairs interaction with DAB2.",
                "evidence": [
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                    {
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                ],
                "uniprot_canonical_ac": "P12023-1"
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            {
                "start_pos": 759,
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                "sequence_org": "N",
                "sequence_mut": "M",
                "comment": "Greatly impairs interaction with DAB2.",
                "evidence": [
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                        "id": "P12023",
                        "url": "https://www.uniprot.org/uniprotkb/P12023"
                    },
                    {
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                    {
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                ],
                "uniprot_canonical_ac": "P12023-1"
            },
            {
                "start_pos": 759,
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                "sequence_org": "N",
                "sequence_mut": "P",
                "comment": "Greatly impairs interaction with DAB2.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "P12023",
                        "url": "https://www.uniprot.org/uniprotkb/P12023"
                    },
                    {
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                        "id": "11247302",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/11247302"
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                    {
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/11517249"
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                ],
                "uniprot_canonical_ac": "P12023-1"
            },
            {
                "start_pos": 760,
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                "sequence_org": "P",
                "sequence_mut": "E",
                "comment": "Greatly impairs interaction with DAB2.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "P12023",
                        "url": "https://www.uniprot.org/uniprotkb/P12023"
                    },
                    {
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        ],
        "record_id": "pubmed.11470803",
        "abstract": "",
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    {
        "title": "Phosphorylation of threonine 156 of the mu2 subunit of the AP2 complex is essential for endocytosis in vitro and in vivo.",
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        "date": "2001",
        "authors": "Olusanya O, Andrews PD, Swedlow JR, Smythe E",
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    {
        "title": "The huntingtin interacting protein HIP1 is a clathrin and alpha-adaptin-binding protein involved in receptor-mediated endocytosis.",
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        ],
        "species": [
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                "name": "Homo sapiens",
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                "evidence": [
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                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.11532990",
        "abstract": "",
        "glycosylation": [],
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    {
        "title": "Clathrin- and AP-2-binding sites in HIP1 uncover a general assembly role for endocytic accessory proteins.",
        "journal": "The Journal of biological chemistry",
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        "authors": "Onishi-Haraikawa Y, Funaki M, Gotoh N, Shibuya M, Inukai K, Katagiri H, Fukushima Y, Anai M, Ogihara T, Sakoda H, Ono H, Kikuchi M, Oka Y, Asano T",
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            },
            {
                "uniprot_canonical_ac": "Q5T1C6-1",
                "protein_name": "Acyl-coenzyme A thioesterase THEM4",
                "gene_name": "THEM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75044-1",
                "protein_name": "SLIT-ROBO Rho GTPase-activating protein 2",
                "gene_name": "SRGAP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P46940-1",
                "protein_name": "Ras GTPase-activating-like protein IQGAP1",
                "gene_name": "IQGAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16512-1",
                "protein_name": "Serine/threonine-protein kinase N1",
                "gene_name": "PKN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU7-1",
                "protein_name": "Tribbles homolog 3",
                "gene_name": "TRIB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WZ64-1",
                "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2",
                "gene_name": "ARAP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15514-1",
                "protein_name": "Amphiregulin",
                "gene_name": "AREG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N4T4-1",
                "protein_name": "Rho guanine nucleotide exchange factor 39",
                "gene_name": "ARHGEF39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13153-1",
                "protein_name": "Serine/threonine-protein kinase PAK 1",
                "gene_name": "PAK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2X7-1",
                "protein_name": "ARF GTPase-activating protein GIT1",
                "gene_name": "GIT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15013-1",
                "protein_name": "Rho guanine nucleotide exchange factor 10",
                "gene_name": "ARHGEF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6B7-1",
                "protein_name": "SLIT-ROBO Rho GTPase-activating protein 1",
                "gene_name": "SRGAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15052-1",
                "protein_name": "Rho guanine nucleotide exchange factor 6",
                "gene_name": "ARHGEF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VW2-1",
                "protein_name": "Rho guanine nucleotide exchange factor 25",
                "gene_name": "ARHGEF25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15085-1",
                "protein_name": "Rho guanine nucleotide exchange factor 11",
                "gene_name": "ARHGEF11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13177-1",
                "protein_name": "Serine/threonine-protein kinase PAK 2",
                "gene_name": "PAK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4K3-1",
                "protein_name": "TNF receptor-associated factor 6",
                "gene_name": "TRAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NR80-1",
                "protein_name": "Rho guanine nucleotide exchange factor 4",
                "gene_name": "ARHGEF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWN8-1",
                "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3",
                "gene_name": "ARAP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12774-1",
                "protein_name": "Rho guanine nucleotide exchange factor 5",
                "gene_name": "ARHGEF5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZSZ5-4",
                "protein_name": "Rho guanine nucleotide exchange factor 18",
                "gene_name": "ARHGEF18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96P48-6",
                "protein_name": "Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1",
                "gene_name": "ARAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94989-1",
                "protein_name": "Rho guanine nucleotide exchange factor 15",
                "gene_name": "ARHGEF15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00401-1",
                "protein_name": "Actin nucleation-promoting factor WASL",
                "gene_name": "WASL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q02297-1",
                "protein_name": "Pro-neuregulin-1, membrane-bound isoform",
                "gene_name": "NRG1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P56975-1",
                "protein_name": "Pro-neuregulin-3, membrane-bound isoform",
                "gene_name": "NRG3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y5S8-1",
                "protein_name": "NADPH oxidase 1",
                "gene_name": "NOX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60890-1",
                "protein_name": "Oligophrenin-1",
                "gene_name": "OPHN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q01638-1",
                "protein_name": "Interleukin-1 receptor-like 1",
                "gene_name": "IL1RL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13009-1",
                "protein_name": "Rho guanine nucleotide exchange factor TIAM1",
                "gene_name": "TIAM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NF50-1",
                "protein_name": "Dedicator of cytokinesis protein 8",
                "gene_name": "DOCK8",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P15391-1",
                "protein_name": "B-lymphocyte antigen CD19",
                "gene_name": "CD19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49771-1",
                "protein_name": "Fms-related tyrosine kinase 3 ligand",
                "gene_name": "FLT3LG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15520-1",
                "protein_name": "Fibroblast growth factor 10",
                "gene_name": "FGF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WUY9-1",
                "protein_name": "DEP domain-containing protein 1B",
                "gene_name": "DEPDC1B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42336-1",
                "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform",
                "gene_name": "PIK3CA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K8-1",
                "protein_name": "Serine/threonine-protein kinase TAO3",
                "gene_name": "TAOK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92731-1",
                "protein_name": "Estrogen receptor beta",
                "gene_name": "ESR2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BSJ8-1",
                "protein_name": "Extended synaptotagmin-1",
                "gene_name": "ESYT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WU20-1",
                "protein_name": "Fibroblast growth factor receptor substrate 2",
                "gene_name": "FRS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P107-1",
                "protein_name": "GEM-interacting protein",
                "gene_name": "GMIP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15063-1",
                "protein_name": "Granule associated Rac and RHOG effector protein 1",
                "gene_name": "GARRE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWZ3-1",
                "protein_name": "Interleukin-1 receptor-associated kinase 4",
                "gene_name": "IRAK4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92619-1",
                "protein_name": "Rho GTPase-activating protein 45",
                "gene_name": "ARHGAP45",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13393-1",
                "protein_name": "Phospholipase D1",
                "gene_name": "PLD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14939-1",
                "protein_name": "Phospholipase D2",
                "gene_name": "PLD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBY0-1",
                "protein_name": "NADPH oxidase 3",
                "gene_name": "NOX3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15882-1",
                "protein_name": "N-chimaerin",
                "gene_name": "CHN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6T4R5-1",
                "protein_name": "Actin remodeling regulator NHS",
                "gene_name": "NHS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14511-1",
                "protein_name": "Pro-neuregulin-2, membrane-bound isoform",
                "gene_name": "NRG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5UE93-1",
                "protein_name": "Phosphoinositide 3-kinase regulatory subunit 6",
                "gene_name": "PIK3R6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5V2-1",
                "protein_name": "Ephexin-1",
                "gene_name": "NGEF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01138-1",
                "protein_name": "Beta-nerve growth factor",
                "gene_name": "NGF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16620-1",
                "protein_name": "BDNF/NT-3 growth factors receptor",
                "gene_name": "NTRK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48736-1",
                "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform",
                "gene_name": "PIK3CG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P85299-1",
                "protein_name": "Proline-rich protein 5",
                "gene_name": "PRR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98171-1",
                "protein_name": "Rho GTPase-activating protein 4",
                "gene_name": "ARHGAP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BPZ7-1",
                "protein_name": "Target of rapamycin complex 2 subunit MAPKAP1",
                "gene_name": "MAPKAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NI28-1",
                "protein_name": "Rho GTPase-activating protein 42",
                "gene_name": "ARHGAP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96QB1-2",
                "protein_name": "Rho GTPase-activating protein 7",
                "gene_name": "DLC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2F6-1",
                "protein_name": "Rho GTPase-activating protein 20",
                "gene_name": "ARHGAP20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRY4-1",
                "protein_name": "Rho GTPase-activating protein 35",
                "gene_name": "ARHGAP35",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH65-1",
                "protein_name": "Switch-associated protein 70",
                "gene_name": "SWAP70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P227-1",
                "protein_name": "Rho GTPase-activating protein 23",
                "gene_name": "ARHGAP23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q17R89-1",
                "protein_name": "Rho GTPase-activating protein 44",
                "gene_name": "ARHGAP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWW6-1",
                "protein_name": "Rho GTPase-activating protein 12",
                "gene_name": "ARHGAP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53QZ3-1",
                "protein_name": "Rho GTPase-activating protein 15",
                "gene_name": "ARHGAP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13017-1",
                "protein_name": "Rho GTPase-activating protein 5",
                "gene_name": "ARHGAP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42331-1",
                "protein_name": "Rho GTPase-activating protein 25",
                "gene_name": "ARHGAP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q52LW3-1",
                "protein_name": "Rho GTPase-activating protein 29",
                "gene_name": "ARHGAP29",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9C0H5-1",
                "protein_name": "Rho GTPase-activating protein 39",
                "gene_name": "ARHGAP39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q2M1Z3-1",
                "protein_name": "Rho GTPase-activating protein 31",
                "gene_name": "ARHGAP31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00161-1",
                "protein_name": "Synaptosomal-associated protein 23",
                "gene_name": "SNAP23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZUJ8-1",
                "protein_name": "Phosphoinositide 3-kinase adapter protein 1",
                "gene_name": "PIK3AP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96N67-1",
                "protein_name": "Dedicator of cytokinesis protein 7",
                "gene_name": "DOCK7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1I0-1",
                "protein_name": "Dedicator of cytokinesis protein 4",
                "gene_name": "DOCK4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JSL3-1",
                "protein_name": "Dedicator of cytokinesis protein 11",
                "gene_name": "DOCK11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7D0-1",
                "protein_name": "Dedicator of cytokinesis protein 5",
                "gene_name": "DOCK5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33681-1",
                "protein_name": "T-lymphocyte activation antigen CD80",
                "gene_name": "CD80",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75962-1",
                "protein_name": "Triple functional domain protein",
                "gene_name": "TRIO",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAA9-1",
                "protein_name": "Vang-like protein 1",
                "gene_name": "VANGL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01135-1",
                "protein_name": "Protransforming growth factor alpha",
                "gene_name": "TGFA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84095-1",
                "protein_name": "Rho-related GTP-binding protein RhoG",
                "gene_name": "RHOG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BY6-1",
                "protein_name": "Dedicator of cytokinesis protein 10",
                "gene_name": "DOCK10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14344-1",
                "protein_name": "Guanine nucleotide-binding protein subunit alpha-13",
                "gene_name": "GNA13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IW93-1",
                "protein_name": "Rho guanine nucleotide exchange factor 19",
                "gene_name": "ARHGEF19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q58EX7-1",
                "protein_name": "Puratrophin-1",
                "gene_name": "PLEKHG4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UQB8-1",
                "protein_name": "BAR/IMD domain-containing adapter protein 2",
                "gene_name": "BAIAP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15836-1",
                "protein_name": "Vesicle-associated membrane protein 3",
                "gene_name": "VAMP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P286-1",
                "protein_name": "Serine/threonine-protein kinase PAK 5",
                "gene_name": "PAK5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q00587-1",
                "protein_name": "Cdc42 effector protein 1",
                "gene_name": "CDC42EP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P11274-1",
                "protein_name": "Breakpoint cluster region protein",
                "gene_name": "BCR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09038-4",
                "protein_name": "Fibroblast growth factor 2",
                "gene_name": "FGF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P52757-1",
                "protein_name": "Beta-chimaerin",
                "gene_name": "CHN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10747-1",
                "protein_name": "T-cell-specific surface glycoprotein CD28",
                "gene_name": "CD28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75914-1",
                "protein_name": "Serine/threonine-protein kinase PAK 3",
                "gene_name": "PAK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L576-1",
                "protein_name": "Cytoplasmic FMR1-interacting protein 1",
                "gene_name": "CYFIP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96F07-1",
                "protein_name": "Cytoplasmic FMR1-interacting protein 2",
                "gene_name": "CYFIP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P29317-1",
                "protein_name": "Ephrin type-A receptor 2",
                "gene_name": "EPHA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04839-1",
                "protein_name": "NADPH oxidase 2",
                "gene_name": "CYBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96AC1-1",
                "protein_name": "Fermitin family homolog 2",
                "gene_name": "FERMT2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13576-1",
                "protein_name": "Ras GTPase-activating-like protein IQGAP2",
                "gene_name": "IQGAP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VI3-1",
                "protein_name": "Ras GTPase-activating-like protein IQGAP3",
                "gene_name": "IQGAP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78504-1",
                "protein_name": "Protein jagged-1",
                "gene_name": "JAG1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15068-1",
                "protein_name": "Guanine nucleotide exchange factor DBS",
                "gene_name": "MCF2L",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10911-1",
                "protein_name": "Proto-oncogene DBL",
                "gene_name": "MCF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R327-1",
                "protein_name": "Rapamycin-insensitive companion of mTOR",
                "gene_name": "RICTOR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60229-1",
                "protein_name": "Kalirin",
                "gene_name": "KALRN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2I1-1",
                "protein_name": "Nischarin",
                "gene_name": "NISCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WYR1-1",
                "protein_name": "Phosphoinositide 3-kinase regulatory subunit 5",
                "gene_name": "PIK3R5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPY6-1",
                "protein_name": "Actin-binding protein WASF3",
                "gene_name": "WASF3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q07889-1",
                "protein_name": "Son of sevenless homolog 1",
                "gene_name": "SOS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14578-1",
                "protein_name": "Citron Rho-interacting kinase",
                "gene_name": "CIT",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P16234-1",
                "protein_name": "Platelet-derived growth factor receptor alpha",
                "gene_name": "PDGFRA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10767-1",
                "protein_name": "Fibroblast growth factor 6",
                "gene_name": "FGF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43320-1",
                "protein_name": "Fibroblast growth factor 16",
                "gene_name": "FGF16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95750-1",
                "protein_name": "Fibroblast growth factor 19",
                "gene_name": "FGF19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08620-1",
                "protein_name": "Fibroblast growth factor 4",
                "gene_name": "FGF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P11487-1",
                "protein_name": "Fibroblast growth factor 3",
                "gene_name": "FGF3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21781-1",
                "protein_name": "Fibroblast growth factor 7",
                "gene_name": "FGF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4F1-1",
                "protein_name": "FERM, ARHGEF and pleckstrin domain-containing protein 1",
                "gene_name": "FARP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZNL6-1",
                "protein_name": "FYVE, RhoGEF and PH domain-containing protein 5",
                "gene_name": "FGD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31371-1",
                "protein_name": "Fibroblast growth factor 9",
                "gene_name": "FGF9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQU5-1",
                "protein_name": "Serine/threonine-protein kinase PAK 6",
                "gene_name": "PAK6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42166-1",
                "protein_name": "Lamina-associated polypeptide 2, isoform alpha",
                "gene_name": "TMPO",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5T2T1-1",
                "protein_name": "MAGUK p55 subfamily member 7",
                "gene_name": "MPP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6IAA8-1",
                "protein_name": "Ragulator complex protein LAMTOR1",
                "gene_name": "LAMTOR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BVC4-1",
                "protein_name": "Target of rapamycin complex subunit LST8",
                "gene_name": "MLST8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94988-4",
                "protein_name": "Protein FAM13A",
                "gene_name": "FAM13A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q07890-1",
                "protein_name": "Son of sevenless homolog 2",
                "gene_name": "SOS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12979-1",
                "protein_name": "Active breakpoint cluster region-related protein",
                "gene_name": "ABR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P52735-1",
                "protein_name": "Guanine nucleotide exchange factor VAV2",
                "gene_name": "VAV2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H5-1",
                "protein_name": "Rac GTPase-activating protein 1",
                "gene_name": "RACGAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15758-1",
                "protein_name": "Neutral amino acid transporter B(0)",
                "gene_name": "SLC1A5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4H2-1",
                "protein_name": "Insulin receptor substrate 2",
                "gene_name": "IRS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60953-2",
                "protein_name": "Cell division control protein 42 homolog",
                "gene_name": "CDC42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43815-1",
                "protein_name": "Striatin",
                "gene_name": "STRN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2A7-1",
                "protein_name": "Nck-associated protein 1",
                "gene_name": "NCKAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14598-1",
                "protein_name": "Neutrophil cytosol factor 1",
                "gene_name": "NCF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31749-1",
                "protein_name": "RAC-alpha serine/threonine-protein kinase",
                "gene_name": "AKT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14155-4",
                "protein_name": "Rho guanine nucleotide exchange factor 7",
                "gene_name": "ARHGEF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P50402-1",
                "protein_name": "Emerin",
                "gene_name": "EMD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92569-1",
                "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma",
                "gene_name": "PIK3R3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42345-1",
                "protein_name": "Serine/threonine-protein kinase mTOR",
                "gene_name": "MTOR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4E7-1",
                "protein_name": "Differentially expressed in FDCP 6 homolog",
                "gene_name": "DEF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42768-1",
                "protein_name": "Actin nucleation-promoting factor WAS",
                "gene_name": "WAS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q68EM7-1",
                "protein_name": "Rho GTPase-activating protein 17",
                "gene_name": "ARHGAP17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96N96-1",
                "protein_name": "Spermatogenesis-associated protein 13",
                "gene_name": "SPATA13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86SJ2-1",
                "protein_name": "Amphoterin-induced protein 2",
                "gene_name": "AMIGO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15311-1",
                "protein_name": "RalA-binding protein 1",
                "gene_name": "RALBP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P03372-1",
                "protein_name": "Estrogen receptor",
                "gene_name": "ESR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63000-1",
                "protein_name": "Ras-related C3 botulinum toxin substrate 1",
                "gene_name": "RAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00459-1",
                "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta",
                "gene_name": "PIK3R2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31751-1",
                "protein_name": "RAC-beta serine/threonine-protein kinase",
                "gene_name": "AKT2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06239-1",
                "protein_name": "Tyrosine-protein kinase Lck",
                "gene_name": "LCK",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02786-1",
                "protein_name": "Transferrin receptor protein 1",
                "gene_name": "TFRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q06124-2",
                "protein_name": "Tyrosine-protein phosphatase non-receptor type 11",
                "gene_name": "PTPN11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05556-1",
                "protein_name": "Integrin beta-1",
                "gene_name": "ITGB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13498-1",
                "protein_name": "Cytochrome b-245 light chain",
                "gene_name": "CYBA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94887-1",
                "protein_name": "FERM, ARHGEF and pleckstrin domain-containing protein 2",
                "gene_name": "FARP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NFA2-1",
                "protein_name": "NADPH oxidase organizer 1",
                "gene_name": "NOXO1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N264-1",
                "protein_name": "Rho GTPase-activating protein 24",
                "gene_name": "ARHGAP24",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95466-1",
                "protein_name": "Formin-like protein 1",
                "gene_name": "FMNL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36888-1",
                "protein_name": "Receptor-type tyrosine-protein kinase FLT3",
                "gene_name": "FLT3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKW4-1",
                "protein_name": "Guanine nucleotide exchange factor VAV3",
                "gene_name": "VAV3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05230-1",
                "protein_name": "Fibroblast growth factor 1",
                "gene_name": "FGF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09619-1",
                "protein_name": "Platelet-derived growth factor receptor beta",
                "gene_name": "PDGFRB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BRR9-1",
                "protein_name": "Rho GTPase-activating protein 9",
                "gene_name": "ARHGAP9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14559-1",
                "protein_name": "Rho GTPase-activating protein 33",
                "gene_name": "ARHGAP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCT0-1",
                "protein_name": "Fibroblast growth factor 22",
                "gene_name": "FGF22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O76093-1",
                "protein_name": "Fibroblast growth factor 18",
                "gene_name": "FGF18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TF74-1",
                "protein_name": "WAS/WASL-interacting protein family member 2",
                "gene_name": "WIPF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P52565-1",
                "protein_name": "Rho GDP-dissociation inhibitor 1",
                "gene_name": "ARHGDIA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43295-1",
                "protein_name": "SLIT-ROBO Rho GTPase-activating protein 3",
                "gene_name": "SRGAP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14161-1",
                "protein_name": "ARF GTPase-activating protein GIT2",
                "gene_name": "GIT2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NGB9-1",
                "protein_name": "WAS/WASL-interacting protein family member 3",
                "gene_name": "WIPF3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14210-1",
                "protein_name": "Hepatocyte growth factor",
                "gene_name": "HGF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23560-1",
                "protein_name": "Neurotrophic factor BDNF precursor form",
                "gene_name": "BDNF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UP2-1",
                "protein_name": "Kinectin",
                "gene_name": "KTN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6W5-1",
                "protein_name": "Actin-binding protein WASF2",
                "gene_name": "WASF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHR4-1",
                "protein_name": "BAR/IMD domain-containing adapter protein 2-like 1",
                "gene_name": "BAIAP2L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92608-1",
                "protein_name": "Dedicator of cytokinesis protein 2",
                "gene_name": "DOCK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H3Q1-1",
                "protein_name": "Cdc42 effector protein 4",
                "gene_name": "CDC42EP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35568-1",
                "protein_name": "Insulin receptor substrate 1",
                "gene_name": "IRS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H8V3-1",
                "protein_name": "Protein ECT2",
                "gene_name": "ECT2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13480-1",
                "protein_name": "GRB2-associated-binding protein 1",
                "gene_name": "GAB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92558-1",
                "protein_name": "Actin-binding protein WASF1",
                "gene_name": "WASF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSV4-3",
                "protein_name": "Protein diaphanous homolog 3",
                "gene_name": "DIAPH3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86Y07-1",
                "protein_name": "Serine/threonine-protein kinase VRK2",
                "gene_name": "VRK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42338-1",
                "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform",
                "gene_name": "PIK3CB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15080-1",
                "protein_name": "Neutrophil cytosol factor 4",
                "gene_name": "NCF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13459-1",
                "protein_name": "Unconventional myosin-IXb",
                "gene_name": "MYO9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43121-1",
                "protein_name": "Cell surface glycoprotein MUC18",
                "gene_name": "MCAM",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55160-1",
                "protein_name": "Nck-associated protein 1-like",
                "gene_name": "NCKAP1L",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00329-1",
                "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform",
                "gene_name": "PIK3CD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A1L390-1",
                "protein_name": "Pleckstrin homology domain-containing family G member 3",
                "gene_name": "PLEKHG3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7P9-1",
                "protein_name": "Pleckstrin homology domain-containing family G member 2",
                "gene_name": "PLEKHG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A1A4S6-1",
                "protein_name": "Rho GTPase-activating protein 10",
                "gene_name": "ARHGAP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15153-1",
                "protein_name": "Ras-related C3 botulinum toxin substrate 2",
                "gene_name": "RAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9ULL1-1",
                "protein_name": "Pleckstrin homology domain-containing family G member 1",
                "gene_name": "PLEKHG1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70Z35-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein",
                "gene_name": "PREX2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z6I6-1",
                "protein_name": "Rho GTPase-activating protein 30",
                "gene_name": "ARHGAP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZUM4-1",
                "protein_name": "Rho GTPase-activating protein 27",
                "gene_name": "ARHGAP27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01127-1",
                "protein_name": "Platelet-derived growth factor subunit B",
                "gene_name": "PDGFB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51617-1",
                "protein_name": "Interleukin-1 receptor-associated kinase 1",
                "gene_name": "IRAK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16513-1",
                "protein_name": "Serine/threonine-protein kinase N2",
                "gene_name": "PKN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51149-1",
                "protein_name": "Ras-related protein Rab-7a",
                "gene_name": "RAB7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N103-1",
                "protein_name": "T-cell activation Rho GTPase-activating protein",
                "gene_name": "TAGAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VT97-1",
                "protein_name": "Rho GTPase-activating protein SYDE2",
                "gene_name": "SYDE2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IVF5-1",
                "protein_name": "Rho guanine nucleotide exchange factor TIAM2",
                "gene_name": "TIAM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16288-1",
                "protein_name": "NT-3 growth factor receptor",
                "gene_name": "NTRK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04629-1",
                "protein_name": "High affinity nerve growth factor receptor",
                "gene_name": "NTRK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08581-1",
                "protein_name": "Hepatocyte growth factor receptor",
                "gene_name": "MET",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35070-1",
                "protein_name": "Probetacellulin",
                "gene_name": "BTC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WUW1-1",
                "protein_name": "Protein BRICK1",
                "gene_name": "BRK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNA1-1",
                "protein_name": "Rho GTPase-activating protein 26",
                "gene_name": "ARHGAP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14739-1",
                "protein_name": "Delta(14)-sterol reductase LBR",
                "gene_name": "LBR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42081-1",
                "protein_name": "T-lymphocyte activation antigen CD86",
                "gene_name": "CD86",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VT25-1",
                "protein_name": "Serine/threonine-protein kinase MRCK alpha",
                "gene_name": "CDC42BPA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z5H3-1",
                "protein_name": "Rho GTPase-activating protein 22",
                "gene_name": "ARHGAP22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TCU6-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein",
                "gene_name": "PREX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q07960-1",
                "protein_name": "Rho GTPase-activating protein 1",
                "gene_name": "ARHGAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O96013-1",
                "protein_name": "Serine/threonine-protein kinase PAK 4",
                "gene_name": "PAK4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q3KR16-1",
                "protein_name": "Pleckstrin homology domain-containing family G member 6",
                "gene_name": "PLEKHG6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BZ29-1",
                "protein_name": "Dedicator of cytokinesis protein 9",
                "gene_name": "DOCK9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IZD9-1",
                "protein_name": "Dedicator of cytokinesis protein 3",
                "gene_name": "DOCK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5T5U3-1",
                "protein_name": "Rho GTPase-activating protein 21",
                "gene_name": "ARHGAP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96HP0-1",
                "protein_name": "Dedicator of cytokinesis protein 6",
                "gene_name": "DOCK6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99836-1",
                "protein_name": "Myeloid differentiation primary response protein MyD88",
                "gene_name": "MYD88",
                "tax_name": "Human"
            },
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    {
        "title": "Phosphorylation of the AP2 mu subunit by AAK1 mediates high affinity binding to membrane protein sorting signals.",
        "journal": "The Journal of cell biology",
        "date": "2002",
        "authors": "Ricotta D, Conner SD, Schmid SL, von Figura K, Honing S",
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                "evidence": [
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        "record_id": "pubmed.11877461",
        "abstract": "",
        "glycosylation": [],
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        "section_stats": [
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                "protein_name": "Src substrate cortactin",
                "gene_name": "CTTN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15514-1",
                "protein_name": "Amphiregulin",
                "gene_name": "AREG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95782-1",
                "protein_name": "AP-2 complex subunit alpha-1",
                "gene_name": "AP2A1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04114-1",
                "protein_name": "Apolipoprotein B-100",
                "gene_name": "APOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P59998-1",
                "protein_name": "Actin-related protein 2/3 complex subunit 4",
                "gene_name": "ARPC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15144-1",
                "protein_name": "Actin-related protein 2/3 complex subunit 2",
                "gene_name": "ARPC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N6T3-1",
                "protein_name": "ADP-ribosylation factor GTPase-activating protein 1",
                "gene_name": "ARFGAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61158-1",
                "protein_name": "Actin-related protein 3",
                "gene_name": "ACTR3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15511-1",
                "protein_name": "Actin-related protein 2/3 complex subunit 5",
                "gene_name": "ARPC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61160-1",
                "protein_name": "Actin-related protein 2",
                "gene_name": "ACTR2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00401-1",
                "protein_name": "Actin nucleation-promoting factor WASL",
                "gene_name": "WASL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25103-1",
                "protein_name": "Substance-P receptor",
                "gene_name": "TACR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96D71-1",
                "protein_name": "RalBP1-associated Eps domain-containing protein 1",
                "gene_name": "REPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P53675-1",
                "protein_name": "Clathrin heavy chain 2",
                "gene_name": "CLTCL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5T0N5-1",
                "protein_name": "Formin-binding protein 1-like",
                "gene_name": "FNBP1L",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92783-1",
                "protein_name": "Signal transducing adapter molecule 1",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P16871-1",
                "protein_name": "Interleukin-7 receptor subunit alpha",
                "gene_name": "IL7R",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63027-1",
                "protein_name": "Vesicle-associated membrane protein 2",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VV43-1",
                "protein_name": "Dyslexia-associated protein KIAA0319",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75146-1",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "O00291-1",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P01185-1",
                "protein_name": "Vasopressin-neurophysin 2-copeptin",
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                "tax_name": "Human"
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            },
            {
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                "protein_name": "Disabled homolog 2",
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                "protein_name": "Vesicular acetylcholine transporter",
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                "protein_name": "Low-density lipoprotein receptor-related protein 2",
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                "protein_name": "Type-1 angiotensin II receptor",
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                "protein_name": "Heat shock cognate 71 kDa protein",
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                "uniprot_canonical_ac": "Q92747-1",
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            {
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            {
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                "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate",
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            {
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                "uniprot_canonical_ac": "Q9UKS6-1",
                "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3",
                "gene_name": "PACSIN3",
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                "uniprot_canonical_ac": "P60709-1",
                "protein_name": "Actin, cytoplasmic 1",
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                "uniprot_canonical_ac": "Q2M2I8-1",
                "protein_name": "AP2-associated protein kinase 1",
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        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "P01133",
                        "url": "https://www.uniprot.org/uniprotkb/P01133"
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    {
        "title": "Serine/threonine phosphorylation of ShcA. Regulation of protein-tyrosine phosphatase-pest binding and involvement in insulin signaling.",
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        "title": "Molecular architecture and functional model of the endocytic AP2 complex.",
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    {
        "title": "A growth factor-dependent nuclear kinase phosphorylates p27(Kip1) and regulates cell cycle progression.",
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        "date": "2002",
        "authors": "Boehm M, Yoshimoto T, Crook MF, Nallamshetty S, True A, Nabel GJ, Nabel EG",
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            {
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            {
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                "tax_name": "Human"
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            {
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            {
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            {
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            {
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            {
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    {
        "title": "Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics.",
        "journal": "The Journal of cell biology",
        "date": "2002",
        "authors": "Wasiak S, Legendre-Guillemin V, Puertollano R, Blondeau F, Girard M, de Heuvel E, Boismenu D, Bell AW, Bonifacino JS, McPherson PS",
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                "gene_name": "ARFGAP1",
                "tax_name": "Human"
            },
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                "protein_name": "Actin-related protein 3",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "O15511-1",
                "protein_name": "Actin-related protein 2/3 complex subunit 5",
                "gene_name": "ARPC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61160-1",
                "protein_name": "Actin-related protein 2",
                "gene_name": "ACTR2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00401-1",
                "protein_name": "Actin nucleation-promoting factor WASL",
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                "tax_name": "Human"
            },
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                "protein_name": "Substance-P receptor",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q96D71-1",
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            {
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                "gene_name": "CLTCL1",
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            },
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                "protein_name": "Formin-binding protein 1-like",
                "gene_name": "FNBP1L",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92783-1",
                "protein_name": "Signal transducing adapter molecule 1",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P16871-1",
                "protein_name": "Interleukin-7 receptor subunit alpha",
                "gene_name": "IL7R",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63027-1",
                "protein_name": "Vesicle-associated membrane protein 2",
                "gene_name": "VAMP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5VV43-1",
                "protein_name": "Dyslexia-associated protein KIAA0319",
                "gene_name": "KIAA0319",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75146-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O00291-1",
                "protein_name": "Huntingtin-interacting protein 1",
                "gene_name": "HIP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01185-1",
                "protein_name": "Vasopressin-neurophysin 2-copeptin",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00443-1",
                "protein_name": "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha",
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                "tax_name": "Human"
            },
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            },
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                "protein_name": "Vesicle-associated membrane protein 8",
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                "tax_name": "Human"
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                "protein_name": "Formin-binding protein 1",
                "gene_name": "FNBP1",
                "tax_name": "Human"
            },
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                "protein_name": "Protransforming growth factor alpha",
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                "protein_name": "Ras-related protein Rab-5B",
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                "protein_name": "Cyclin-G-associated kinase",
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            },
            {
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                "protein_name": "Vesicular acetylcholine transporter",
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                "tax_name": "Human"
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                "protein_name": "Type-1 angiotensin II receptor",
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                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
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            },
            {
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                "protein_name": "Heat shock cognate 71 kDa protein",
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            {
                "uniprot_canonical_ac": "Q96B97-1",
                "protein_name": "SH3 domain-containing kinase-binding protein 1",
                "gene_name": "SH3KBP1",
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            },
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                "uniprot_canonical_ac": "P63010-1",
                "protein_name": "AP-2 complex subunit beta",
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                "protein_name": "Actin, cytoplasmic 2",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
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            },
            {
                "uniprot_canonical_ac": "O14641-1",
                "protein_name": "Segment polarity protein dishevelled homolog DVL-2",
                "gene_name": "DVL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92747-1",
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                "gene_name": "ARPC1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62330-1",
                "protein_name": "ADP-ribosylation factor 6",
                "gene_name": "ARF6",
                "tax_name": "Human"
            },
            {
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                "protein_name": "Low density lipoprotein receptor adapter protein 1",
                "gene_name": "LDLRAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01130-1",
                "protein_name": "Low-density lipoprotein receptor",
                "gene_name": "LDLR",
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                "protein_name": "AP-2 complex subunit mu",
                "gene_name": "AP2M1",
                "tax_name": "Human"
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            {
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                "protein_name": "Ras-related protein Rab-5A",
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                "protein_name": "Amphiphysin",
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                "tax_name": "Human"
            },
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                "protein_name": "Transferrin receptor protein 1",
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            },
            {
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                "protein_name": "Inositol polyphosphate 5-phosphatase OCRL",
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            },
            {
                "uniprot_canonical_ac": "Q14677-1",
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                "gene_name": "CLINT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9ULV1-1",
                "protein_name": "Frizzled-4",
                "gene_name": "FZD4",
                "tax_name": "Human"
            },
            {
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                "protein_name": "GTPase-activating protein and VPS9 domain-containing protein 1",
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                "tax_name": "Human"
            },
            {
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                "protein_name": "Polyphosphatidylinositol phosphatase SYNJ2",
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            },
            {
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                "protein_name": "Serotransferrin",
                "gene_name": "TF",
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            },
            {
                "uniprot_canonical_ac": "Q9NZ52-1",
                "protein_name": "ADP-ribosylation factor-binding protein GGA3",
                "gene_name": "GGA3",
                "tax_name": "Human"
            },
            {
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                "protein_name": "Protein Wnt-5a",
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                "tax_name": "Human"
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            {
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            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
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            },
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                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
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            },
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                "tax_name": "Human"
            },
            {
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                "protein_name": "Clathrin light chain A",
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                "tax_name": "Human"
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            },
            {
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                "uniprot_canonical_ac": "Q9BY11-1",
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                "gene_name": "PACSIN1",
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            },
            {
                "uniprot_canonical_ac": "O43426-1",
                "protein_name": "Polyphosphatidylinositol phosphatase SYNJ1",
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                "tax_name": "Human"
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            {
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            },
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            },
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                "protein_name": "Polyubiquitin-B",
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                "protein_name": "Clathrin light chain B",
                "gene_name": "CLTB",
                "tax_name": "Human"
            },
            {
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                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
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            },
            {
                "uniprot_canonical_ac": "Q05193-1",
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                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q9Y6I3-2",
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            },
            {
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                "protein_name": "Ras-related protein Rab-5C",
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            },
            {
                "uniprot_canonical_ac": "Q0JRZ9-1",
                "protein_name": "F-BAR domain only protein 2",
                "gene_name": "FCHO2",
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            },
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                "uniprot_canonical_ac": "Q9UQ16-1",
                "protein_name": "Dynamin-3",
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                "tax_name": "Human"
            },
            {
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                "protein_name": "Epidermal growth factor receptor substrate 15",
                "gene_name": "EPS15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95208-1",
                "protein_name": "Epsin-2",
                "gene_name": "EPN2",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "Q8WXE9-1",
                "protein_name": "Stonin-2",
                "gene_name": "STON2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P11717-1",
                "protein_name": "Cation-independent mannose-6-phosphate receptor",
                "gene_name": "IGF2R",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NY64-1",
                "protein_name": "Solute carrier family 2, facilitated glucose transporter member 8",
                "gene_name": "SLC2A8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99075-1",
                "protein_name": "Proheparin-binding EGF-like growth factor",
                "gene_name": "HBEGF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20645-1",
                "protein_name": "Cation-dependent mannose-6-phosphate receptor",
                "gene_name": "M6PR",
                "tax_name": "Human"
            },
            {
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                "protein_name": "Adaptin ear-binding coat-associated protein 2",
                "gene_name": "NECAP2",
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            },
            {
                "uniprot_canonical_ac": "Q8NC96-1",
                "protein_name": "Adaptin ear-binding coat-associated protein 1",
                "gene_name": "NECAP1",
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            },
            {
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                "protein_name": "Epigen",
                "gene_name": "EPGN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14944-1",
                "protein_name": "Proepiregulin",
                "gene_name": "EREG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P53680-1",
                "protein_name": "AP-2 complex subunit sigma",
                "gene_name": "AP2S1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94973-1",
                "protein_name": "AP-2 complex subunit alpha-2",
                "gene_name": "AP2A2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15642-1",
                "protein_name": "Cdc42-interacting protein 4",
                "gene_name": "TRIP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P00533-1",
                "protein_name": "Epidermal growth factor receptor",
                "gene_name": "EGFR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P22681-1",
                "protein_name": "E3 ubiquitin-protein ligase CBL",
                "gene_name": "CBL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14964-1",
                "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate",
                "gene_name": "HGS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
                "protein_name": "Polyubiquitin-C",
                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKS6-1",
                "protein_name": "Protein kinase C and casein kinase substrate in neurons protein 3",
                "gene_name": "PACSIN3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75886-1",
                "protein_name": "Signal transducing adapter molecule 2",
                "gene_name": "STAM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08172-1",
                "protein_name": "Muscarinic acetylcholine receptor M2",
                "gene_name": "CHRM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60709-1",
                "protein_name": "Actin, cytoplasmic 1",
                "gene_name": "ACTB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99962-1",
                "protein_name": "Endophilin-A1",
                "gene_name": "SH3GL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q2M2I8-1",
                "protein_name": "AP2-associated protein kinase 1",
                "gene_name": "AAK1",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "P01133",
                        "url": "https://www.uniprot.org/uniprotkb/P01133"
                    }
                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
            }
        ],
        "record_id": "pubmed.12213833",
        "abstract": "",
        "glycosylation": [],
        "mutagenesis": [],
        "snv": [],
        "phosphorylation": [],
        "glycation": [],
        "section_stats": [
            {
                "table_id": "referenced_proteins",
                "table_stats": [
                    {
                        "field": "total",
                        "count": 131
                    }
                ],
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        "title": "Sprouty2 attenuates epidermal growth factor receptor ubiquitylation and endocytosis, and consequently enhances Ras/ERK signalling.",
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        "authors": "Wong ES, Fong CW, Lim J, Yusoff P, Low BC, Langdon WY, Guy GR",
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        "title": "ARF6-GTP recruits Nm23-H1 to facilitate dynamin-mediated endocytosis during adherens junctions disassembly.",
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    {
        "title": "Phosphorylation of key serine residues is required for internalization of the complement 5a (C5a) anaphylatoxin receptor via a beta-arrestin, dynamin, and clathrin-dependent pathway.",
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    {
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    {
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    {
        "title": "ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type Igamma.",
        "journal": "The Journal of cell biology",
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        "authors": "Krauss M, Kinuta M, Wenk MR, De Camilli P, Takei K, Haucke V",
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    {
        "title": "Xenopus autosomal recessive hypercholesterolemia protein couples lipoprotein receptors with the AP-2 complex in oocytes and embryos and is required for vitellogenesis.",
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        "authors": "Zhou Y, Zhang J, King ML",
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        "record_id": "pubmed.12952949",
        "abstract": "",
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                "table_id": "glycosylation_automatic_literature_mining",
                "table_stats": [
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    {
        "title": "Dishevelled 2 recruits beta-arrestin 2 to mediate Wnt5A-stimulated endocytosis of Frizzled 4.",
        "journal": "Science (New York, N.Y.)",
        "date": "2003",
        "authors": "Chen W, ten Berge D, Brown J, Ahn S, Hu LA, Miller WE, Caron MG, Barak LS, Nusse R, Lefkowitz RJ",
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                "protein_name": "AP2-associated protein kinase 1",
                "gene_name": "AAK1",
                "tax_name": "Human"
            }
        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                        "id": "P01133",
                        "url": "https://www.uniprot.org/uniprotkb/P01133"
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                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
            }
        ],
        "record_id": "pubmed.12958364",
        "abstract": "",
        "glycosylation": [],
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            {
                "table_id": "glycosylation_automatic_literature_mining",
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        ]
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    {
        "title": "Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif.",
        "journal": "EMBO reports",
        "date": "2003",
        "authors": "Ritter B, Philie J, Girard M, Tung EC, Blondeau F, McPherson PS",
        "reference": {
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            "id": "14555962",
            "url": "https://pubmed.ncbi.nlm.nih.gov/14555962"
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        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.14581451",
        "abstract": "",
        "glycosylation": [],
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    {
        "title": "AAK1-mediated micro2 phosphorylation is stimulated by assembled clathrin.",
        "journal": "Traffic (Copenhagen, Denmark)",
        "date": "2003",
        "authors": "Conner SD, Schroter T, Schmid SL",
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        "title": "Endophilin is required for synaptic vesicle endocytosis by localizing synaptojanin.",
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        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                        "id": "P01133",
                        "url": "https://www.uniprot.org/uniprotkb/P01133"
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                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.14622579",
        "abstract": "",
        "glycosylation": [],
        "mutagenesis": [],
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        "phosphorylation": [],
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        "section_stats": [
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        ],
        "record_id": "pubmed.14662753",
        "abstract": "",
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        "title": "The Mechanism of Hsp90 regulation by the protein kinase-specific cochaperone p50(cdc37).",
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