[ { "title": "Characterization of regulatory events associated with membrane targeting of p90 ribosomal S6 kinase 1.", "journal": "Molecular and cellular biology", "date": "2001", "authors": "Richards SA, Dreisbach VC, Murphy LO, Blenis J", "reference": { "type": "PubMed", "id": "11585927", "url": "https://pubmed.ncbi.nlm.nih.gov/11585927" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51812-1", "protein_name": "Ribosomal protein S6 kinase alpha-3", "gene_name": "RPS6KA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15349-1", "protein_name": "Ribosomal protein S6 kinase alpha-2", "gene_name": "RPS6KA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK32-1", "protein_name": "Ribosomal protein S6 kinase alpha-6", "gene_name": "RPS6KA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15418-1", "protein_name": "Ribosomal protein S6 kinase alpha-1", "gene_name": "RPS6KA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15530-1", "protein_name": "3-phosphoinositide-dependent protein kinase 1", "gene_name": "PDPK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11585927", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"uniprot_canonical_ac": "Q9BUB5-1", "protein_name": "MAP kinase-interacting serine/threonine-protein kinase 1", "gene_name": "MKNK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43597-1", "protein_name": "Protein sprouty homolog 2", "gene_name": "SPRY2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A GRASP55-rab2 effector complex linking Golgi structure to membrane traffic.", "journal": "The Journal of cell biology", "date": "2001", "authors": "Short B, Preisinger C, Korner R, Kopajtich R, Byron O, Barr FA", "reference": { "type": "PubMed", "id": "11739401", "url": "https://pubmed.ncbi.nlm.nih.gov/11739401" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99JX3-1", "protein_name": "Golgi reassembly-stacking protein 2", "gene_name": "Gorasp2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AYB8-1", "protein_name": "Golgin-45", "gene_name": "Blzf1", "tax_name": "Rat" }, { "uniprot_canonical_ac": "P53350-1", "protein_name": "Serine/threonine-protein kinase PLK1", "gene_name": "PLK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06493-1", "protein_name": "Cyclin-dependent kinase 1", "gene_name": "CDK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U4-1", "protein_name": "Ras-related protein Rab-1B", "gene_name": "RAB1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q62839-1", "protein_name": "Golgin subfamily A member 2", "gene_name": "Golga2", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q9R064-1", "protein_name": "Golgi reassembly-stacking protein 2", "gene_name": "Gorasp2", "tax_name": "Rat" }, { "uniprot_canonical_ac": "O35254-1", "protein_name": "Golgi reassembly-stacking protein 1", "gene_name": "Gorasp1", "tax_name": "Rat" }, { "uniprot_canonical_ac": "O60763-1", "protein_name": "General vesicular transport factor p115", "gene_name": "USO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62820-1", "protein_name": "Ras-related protein Rab-1A", "gene_name": "RAB1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95067-1", "protein_name": "G2/mitotic-specific cyclin-B2", "gene_name": "CCNB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14635-1", "protein_name": 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Biol. Chem.", "date": "2002", "authors": "Sano Hiroyuki, Liu Simon C H, Lane William S, Piletz John E, Lienhard Gustav E", "reference": { "type": "PubMed", "id": "11912194", "url": "https://pubmed.ncbi.nlm.nih.gov/11912194" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2I1-1", "protein_name": "Nischarin", "gene_name": "NISCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14654-1", "protein_name": "Insulin receptor substrate 4", "gene_name": "IRS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08648-1", "protein_name": "Integrin alpha-5", "gene_name": "ITGA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase 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"Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12391162", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 14 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", 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cell", "date": "2002", "authors": "Lax I, Wong A, Lamothe B, Lee A, Frost A, Hawes J, Schlessinger J", "reference": { "type": "PubMed", "id": "12419216", "url": "https://pubmed.ncbi.nlm.nih.gov/12419216" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15520-1", "protein_name": "Fibroblast growth factor 10", "gene_name": "FGF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "FRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09038-4", "protein_name": "Fibroblast growth factor 2", "gene_name": 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622, "end_pos": 622, "sequence_org": "R", "sequence_mut": "*", "comment": "Germline mutation passed 1 filters: glycogene of type=glycogene, fibroblast growth factor receptor.", "chr_id": "8", "chr_pos": "38414892", "ref_nt": "A", "alt_nt": "null", "minor_allelic_frequency": "", "site_lbl": "R622", "keywords": [ "ebi", "germline", "disease" ], "disease": [ { "disease_id": "DOID:0090070", "recommended_name": { "id": "DOID:0090070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090070", "name": "hypogonadotropic hypogonadism", "description": "A hypogonadism characterized by a impaired signalling by gonadotrpin relasing hormone." }, "synonyms": [ { "id": "DOID:0090070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090070", "name": "congenital idiopathic hypogonadotropic hypogonadism", "description": "" }, { "id": "DOID:0090070", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090070", 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}, { "title": "Tyrosine phosphorylation of Sprouty2 enhances its interaction with c-Cbl and is crucial for its function.", "journal": "The Journal of biological chemistry", "date": "2003", "authors": "Fong CW, Leong HF, Wong ES, Lim J, Yusoff P, Guy GR", "reference": { "type": "PubMed", "id": "12815057", "url": "https://pubmed.ncbi.nlm.nih.gov/12815057" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15520-1", "protein_name": "Fibroblast growth factor 10", "gene_name": "FGF10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WU20-1", "protein_name": "Fibroblast growth factor receptor substrate 2", "gene_name": "FRS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUB5-1", "protein_name": "MAP kinase-interacting serine/threonine-protein kinase 1", "gene_name": "MKNK1", "tax_name": "Human" }, { 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by epidermal growth factor and cell adhesion interacts with and phosphorylates vinexin.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Mitsushima M, Suwa A, Amachi T, Ueda K, Kioka N", "reference": { "type": "PubMed", "id": "15184391", "url": "https://pubmed.ncbi.nlm.nih.gov/15184391" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9R1Z8-1", "protein_name": "Vinexin", "gene_name": "Sorbs3", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O60504-1", "protein_name": "Vinexin", "gene_name": "SORBS3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MCL1 is phosphorylated in the PEST region and stabilized upon ERK activation in viable cells, and at additional sites with cytotoxic okadaic acid or taxol.", "journal": "Oncogene", "date": "2004", "authors": "Domina AM, Vrana JA, Gregory MA, Hann SR, Craig RW", "reference": { "type": "PubMed", "id": "15241487", "url": "https://pubmed.ncbi.nlm.nih.gov/15241487" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07820-1", "protein_name": "Induced myeloid leukemia cell differentiation protein Mcl-1", "gene_name": "MCL1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 162, "end_pos": 162, "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes mitochondrial 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No effect on phosphorylation induced by okadaic acid or taxol.", "evidence": [ { "database": "UniProtKB", "id": "Q07820", "url": "https://www.uniprot.org/uniprotkb/Q07820" }, { "database": "PubMed", "id": "15241487", "url": "https://pubmed.ncbi.nlm.nih.gov/15241487" } ], "uniprot_canonical_ac": "Q07820-1" }, { "start_pos": 163, "end_pos": 163, "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on mitochondrial localization.", "evidence": [ { "database": "UniProtKB", "id": "Q07820", "url": "https://www.uniprot.org/uniprotkb/Q07820" }, { "database": "PubMed", "id": "15241487", "url": "https://pubmed.ncbi.nlm.nih.gov/15241487" } ], "uniprot_canonical_ac": "Q07820-1" }, { "start_pos": 163, "end_pos": 163, "sequence_org": "T", "sequence_mut": "E", "comment": "No effect on mitochondrial localization.", "evidence": [ { "database": "UniProtKB", "id": "Q07820", "url": "https://www.uniprot.org/uniprotkb/Q07820" }, { "database": "PubMed", "id": "15241487", "url": 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[] } ] }, { "title": "FRS2-dependent SRC activation is required for fibroblast growth factor receptor-induced phosphorylation of Sprouty and suppression of ERK activity.", "journal": "Journal of cell science", "date": "2004", "authors": "Li X, Brunton VG, Burgar HR, Wheldon LM, Heath JK", "reference": { "type": "PubMed", "id": "15564375", "url": "https://pubmed.ncbi.nlm.nih.gov/15564375" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUB5-1", "protein_name": "MAP kinase-interacting serine/threonine-protein kinase 1", "gene_name": "MKNK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation of carboxyl-terminal tyrosines modulates the specificity of Sprouty-2 inhibition of different signaling pathways.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Rubin C, Zwang Y, Vaisman N, Ron D, Yarden Y", "reference": { "type": "PubMed", "id": "15637081", "url": "https://pubmed.ncbi.nlm.nih.gov/15637081" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUB5-1", "protein_name": "MAP kinase-interacting serine/threonine-protein kinase 1", "gene_name": "MKNK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of Raf-1 by direct feedback phosphorylation.", "journal": "Molecular cell", "date": "2005", "authors": "Dougherty MK, Muller J, Ritt DA, Zhou M, Zhou XZ, Copeland TD, Conrads TP, Veenstra TD, Lu KP, Morrison DK", "reference": { "type": "PubMed", "id": "15664191", "url": "https://pubmed.ncbi.nlm.nih.gov/15664191" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10398-1", "protein_name": "Serine/threonine-protein kinase A-Raf", "gene_name": "ARAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26045-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 3", "gene_name": "PTPN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27448-5", "protein_name": "MAP/microtubule affinity-regulating kinase 3", "gene_name": "MARK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"end_pos": 418, "sequence_org": "S", "sequence_mut": "A", "comment": "No net loss of phosphorylation, this may be due to a compensatory phosphorylation of T-422 in vitro.", "evidence": [ { "database": "UniProtKB", "id": "Q13322", "url": "https://www.uniprot.org/uniprotkb/Q13322" }, { "database": "PubMed", "id": "15952796", "url": "https://pubmed.ncbi.nlm.nih.gov/15952796" } ], "uniprot_canonical_ac": "Q13322-1" }, { "start_pos": 476, "end_pos": 476, "sequence_org": "S", "sequence_mut": "A", "comment": "Loss of phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "Q13322", "url": "https://www.uniprot.org/uniprotkb/Q13322" }, { "database": "PubMed", "id": "15952796", "url": "https://pubmed.ncbi.nlm.nih.gov/15952796" } ], "uniprot_canonical_ac": "Q13322-1" } ], "phosphorylation": [ { "start_pos": 150, "end_pos": 150, "kinase_uniprot_canonical_ac": "P27361-1", "kinase_gene_name": "MAPK3", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q13322", 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{ "database": "iPTMnet", "id": "Q13322", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q13322" }, { "database": "PubMed", "id": "21659604", "url": "https://pubmed.ncbi.nlm.nih.gov/21659604" }, { "database": "PubMed", "id": "15952796", "url": "https://pubmed.ncbi.nlm.nih.gov/15952796" } ], "site_lbl": "Ser476", "uniprot_canonical_ac": "Q13322-1" } ], "record_id": "pubmed.15952796", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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Biophys. Res. Commun.", "date": "2005", "authors": "Ohori Makoto, Kinoshita Takayoshi, Okubo Mitsuru, Sato Kentaro, Yamazaki Akiko, Arakawa Hiroyuki, Nishimura Shintaro, Inamura Noriaki, Nakajima Hidenori, Neya Masahiro, Miyake Hiroshi, Fujii Takashi", "reference": { "type": "PubMed", "id": "16139248", "url": "https://pubmed.ncbi.nlm.nih.gov/16139248" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16139248", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Crystal structure of human ERK2 complexed with a pyrazolo[3,4-c]pyridazine derivative.", "journal": "Bioorg. Med. Chem. 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transcription factor 4b with both extracellular signal-regulated kinase mitogen-activated protein kinase and dual-specificity tyrosine phosphatase DUSP26.", "journal": "Molecular and cellular biology", "date": "2006", "authors": "Hu Y, Mivechi NF", "reference": { "type": "PubMed", "id": "16581800", "url": "https://pubmed.ncbi.nlm.nih.gov/16581800" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9D700-1", "protein_name": "Dual specificity protein phosphatase 26", "gene_name": "Dusp26", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P45983-1", "protein_name": "Mitogen-activated protein kinase 8", "gene_name": "MAPK8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BV47-1", "protein_name": "Dual specificity protein phosphatase 26", "gene_name": "DUSP26", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "P23352-1", "protein_name": "Anosmin-1", "gene_name": "ANOS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31371-1", "protein_name": "Fibroblast growth factor 9", "gene_name": "FGF9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11362-1", "protein_name": "Fibroblast growth factor receptor 1", "gene_name": "FGFR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05230-1", "protein_name": "Fibroblast growth factor 1", "gene_name": "FGF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HCT0-1", "protein_name": "Fibroblast growth factor 22", "gene_name": "FGF22", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": 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"CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16764984", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"protein_name": "Dual specificity protein phosphatase 2", "gene_name": "DUSP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16690-1", "protein_name": "Dual specificity protein phosphatase 5", "gene_name": "DUSP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53042-1", "protein_name": "Serine/threonine-protein phosphatase 5", "gene_name": "Ppp5c", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53041-1", "protein_name": "Serine/threonine-protein phosphatase 5", "gene_name": "PPP5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z569-1", "protein_name": "BRCA1-associated protein", "gene_name": "BRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVT5-1", "protein_name": "Kinase suppressor of Ras 1", "gene_name": "KSR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35236-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 7", "gene_name": "PTPN7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13202-1", "protein_name": "Dual specificity protein phosphatase 8", "gene_name": "DUSP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY84-1", "protein_name": "Dual specificity protein phosphatase 16", "gene_name": "DUSP16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13115-1", "protein_name": "Dual specificity protein phosphatase 4", "gene_name": "DUSP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16828-1", "protein_name": "Dual specificity protein phosphatase 6", "gene_name": "DUSP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99956-1", "protein_name": "Dual specificity protein phosphatase 9", "gene_name": "DUSP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { 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"sequence_org": "H", "sequence_mut": "Q", "comment": "Catalytically inactive; no effect on interaction with CRY2 but increases the stability of the interaction with CSNK1E. No effect on RAF1 phosphorylation.", "evidence": [ { "database": "UniProtKB", "id": "P53041", "url": "https://www.uniprot.org/uniprotkb/P53041" }, { "database": "PubMed", "id": "16790549", "url": "https://pubmed.ncbi.nlm.nih.gov/16790549" }, { "database": "PubMed", "id": "16892053", "url": "https://pubmed.ncbi.nlm.nih.gov/16892053" }, { "database": "PubMed", "id": "19948726", "url": "https://pubmed.ncbi.nlm.nih.gov/19948726" } ], "uniprot_canonical_ac": "P53041-1" }, { "start_pos": 97, "end_pos": 97, "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of interaction with HSP90AA1. No effect on interaction with S100A1, S100A2 and S100A6. 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Med. Chem.", "date": "2007", "authors": "Aronov Alex M, Baker Christopher, Bemis Guy W, Cao Jingrong, Chen Guanjing, Ford Pamella J, Germann Ursula A, Green Jeremy, Hale Michael R, Jacobs Marc, Janetka James W, Maltais Francois, Martinez-Botella Gabriel, Namchuk Mark N, Straub Judy, Tang Qing, Xie Xiaoling", "reference": { "type": "PubMed", "id": "17300186", "url": "https://pubmed.ncbi.nlm.nih.gov/17300186" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17300186", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mutations of beta-arrestin 2 that limit self-association also interfere with interactions with the beta2-adrenoceptor and the ERK1/2 MAPKs: implications for beta2-adrenoceptor signalling via the ERK1/2 MAPKs.", "journal": "Biochem. J.", "date": "2008", "authors": "Xu Tian-Rui, Baillie George S, Bhari Narinder, Houslay Thomas M, Pitt Andrew M, Adams David R, Kolch Walter, Houslay Miles D, Milligan Graeme", "reference": { "type": "PubMed", "id": "18435604", "url": "https://pubmed.ncbi.nlm.nih.gov/18435604" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53779-1", "protein_name": "Mitogen-activated protein kinase 10", "gene_name": "MAPK10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32120-1", "protein_name": "Beta-arrestin-2", "gene_name": "ARRB2", "tax_name": "Bovine" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 285, "end_pos": 286, "sequence_org": "KR", "sequence_mut": "AA", "comment": "Lowers self-association; impairs interaction with ADRB2, MAPK1 and MAPK3; no effect on interaction with MAPK10.", "evidence": [ { "database": "UniProtKB", "id": "P32120", "url": "https://www.uniprot.org/uniprotkb/P32120" }, { "database": "PubMed", "id": "18435604", "url": "https://pubmed.ncbi.nlm.nih.gov/18435604" } ], "uniprot_canonical_ac": "P32120-1" }, { "start_pos": 295, "end_pos": 295, "sequence_org": "K", "sequence_mut": "A", "comment": "Impairs interaction with ADRB2, MAPK1 ANDMAPK3; no effect on interaction with MAPK10.", "evidence": [ { "database": "UniProtKB", "id": "P32120", "url": "https://www.uniprot.org/uniprotkb/P32120" }, { "database": "PubMed", "id": "18435604", "url": "https://pubmed.ncbi.nlm.nih.gov/18435604" } ], 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{ "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RKTG sequesters B-Raf to the Golgi apparatus and inhibits the proliferation and tumorigenicity of human malignant melanoma cells.", "journal": "Carcinogenesis", "date": "2008", "authors": "Fan F, Feng L, He J, Wang X, Jiang X, Zhang Y, Wang Z, Chen Y", "reference": { "type": "PubMed", "id": "18515281", "url": "https://pubmed.ncbi.nlm.nih.gov/18515281" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6TCH7-1", "protein_name": "Progestin and adipoQ receptor family member 3", "gene_name": "PAQR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform", "gene_name": "PPP2CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6W6-1", "protein_name": "Dual specificity protein phosphatase 10", "gene_name": "DUSP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16829-1", "protein_name": "Dual specificity protein phosphatase 7", "gene_name": "DUSP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28562-1", "protein_name": "Dual specificity protein phosphatase 1", "gene_name": "DUSP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30086-1", "protein_name": "Phosphatidylethanolamine-binding protein 1", "gene_name": "PEBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53778-1", "protein_name": "Mitogen-activated protein kinase 12", "gene_name": "MAPK12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05923-1", "protein_name": "Dual specificity protein phosphatase 2", "gene_name": "DUSP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16690-1", "protein_name": "Dual specificity protein phosphatase 5", "gene_name": "DUSP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16537-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "gene_name": "PPP2R5E", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15172-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform", "gene_name": "PPP2R5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53041-1", "protein_name": "Serine/threonine-protein phosphatase 5", "gene_name": "PPP5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z569-1", "protein_name": "BRCA1-associated protein", "gene_name": "BRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IVT5-1", "protein_name": "Kinase suppressor of Ras 1", "gene_name": "KSR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35236-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 7", "gene_name": "PTPN7", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 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"gene_name": "CCNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61019-1", "protein_name": "Ras-related protein Rab-2A", "gene_name": "RAB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q08379-1", "protein_name": "Golgin subfamily A member 2", "gene_name": "GOLGA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQQ3-1", "protein_name": "Golgi reassembly-stacking protein 1", "gene_name": "GORASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H8Y8-1", "protein_name": "Golgi reassembly-stacking protein 2", "gene_name": "GORASP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2G9-1", "protein_name": "Golgin-45", "gene_name": "BLZF1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19651986", 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"glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20117945", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 23 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The role of GRASP65 in Golgi cisternal stacking and cell cycle progression.", "journal": "Traffic (Copenhagen, Denmark)", "date": "2010", "authors": "Tang D, Yuan H, Wang Y", "reference": { "type": "PubMed", "id": "20214750", "url": "https://pubmed.ncbi.nlm.nih.gov/20214750" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53350-1", "protein_name": "Serine/threonine-protein kinase PLK1", "gene_name": "PLK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06493-1", "protein_name": "Cyclin-dependent kinase 1", "gene_name": "CDK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U4-1", "protein_name": "Ras-related protein Rab-1B", "gene_name": "RAB1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60763-1", "protein_name": "General vesicular transport factor p115", "gene_name": "USO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62820-1", "protein_name": "Ras-related protein Rab-1A", "gene_name": "RAB1A", "tax_name": "Human" }, { 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PTPH1 dephosphorylates and cooperates with p38gamma MAPK to increase ras oncogenesis through PDZ-mediated interaction.", "journal": "Cancer research", "date": "2010", "authors": "Hou SW, Zhi HY, Pohl N, Loesch M, Qi XM, Li RS, Basir Z, Chen G", "reference": { "type": "PubMed", "id": "20332238", "url": "https://pubmed.ncbi.nlm.nih.gov/20332238" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01112-1", "protein_name": "GTPase HRas", "gene_name": "HRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01111-1", "protein_name": "GTPase NRas", "gene_name": "NRAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6TCH7-1", "protein_name": "Progestin and adipoQ receptor family member 3", "gene_name": "PAQR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62714-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit 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"uniprot_canonical_ac": "P35236-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 7", "gene_name": "PTPN7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13202-1", "protein_name": "Dual specificity protein phosphatase 8", "gene_name": "DUSP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY84-1", "protein_name": "Dual specificity protein phosphatase 16", "gene_name": "DUSP16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13115-1", "protein_name": "Dual specificity protein phosphatase 4", "gene_name": "DUSP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16828-1", "protein_name": "Dual specificity protein phosphatase 6", "gene_name": "DUSP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99956-1", "protein_name": "Dual specificity protein phosphatase 9", "gene_name": "DUSP9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15056-1", "protein_name": "Serine/threonine-protein kinase B-raf", "gene_name": "BRAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04049-1", "protein_name": "RAF proto-oncogene serine/threonine-protein kinase", "gene_name": "RAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31946-1", "protein_name": "14-3-3 protein beta/alpha", "gene_name": "YWHAB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10398-1", "protein_name": "Serine/threonine-protein kinase A-Raf", "gene_name": "ARAF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26045-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 3", "gene_name": "PTPN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27448-5", "protein_name": "MAP/microtubule affinity-regulating kinase 3", "gene_name": "MARK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30154-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "gene_name": "PPP2R1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30153-1", "protein_name": "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "gene_name": "PPP2R1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P67775-1", "protein_name": "Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform", "gene_name": "PPP2CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14738-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "gene_name": "PPP2R5D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13362-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "gene_name": "PPP2R5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15173-1", "protein_name": "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform", "gene_name": "PPP2R5B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20332238", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 40 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": 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Part A", "date": "2010", "authors": "Rauen KA, Tidyman WE, Estep AL, Sampath S, Peltier HM, Bale SJ, Lacassie Y", "reference": { "type": "PubMed", "id": "20358587", "url": "https://pubmed.ncbi.nlm.nih.gov/20358587" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P36507-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 2", "gene_name": "MAP2K2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02750-1", "protein_name": "Dual specificity mitogen-activated protein kinase kinase 1", "gene_name": "MAP2K1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": 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Rv3655c proteins participate in the suppression of macrophage apoptosis.", "journal": "PloS one", "date": "2010", "authors": "Danelishvili L, Yamazaki Y, Selker J, Bermudez LE", "reference": { "type": "PubMed", "id": "20454556", "url": "https://pubmed.ncbi.nlm.nih.gov/20454556" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23246-1", "protein_name": "Splicing factor, proline- and glutamine-rich", "gene_name": "SFPQ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q63HN8-3", "protein_name": "E3 ubiquitin-protein ligase RNF213", "gene_name": "RNF213", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08311-1", "protein_name": "Cathepsin G", "gene_name": "CTSG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49840-1", "protein_name": "Glycogen synthase kinase-3 alpha", "gene_name": "GSK3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27361-1", "protein_name": "Mitogen-activated protein kinase 3", "gene_name": "MAPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14373-1", "protein_name": "Zinc finger protein RFP", "gene_name": "TRIM27", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P28482", "url": "https://www.uniprot.org/uniprotkb/P28482" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20454556", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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Cell physiology", "date": "2010", "authors": "Bermudez O, Pages G, Gimond C", "reference": { "type": "PubMed", "id": "20463170", "url": "https://pubmed.ncbi.nlm.nih.gov/20463170" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15121-1", "protein_name": "Astrocytic phosphoprotein PEA-15", "gene_name": "PEA15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6W6-1", "protein_name": "Dual specificity protein phosphatase 10", "gene_name": "DUSP10", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16829-1", "protein_name": "Dual specificity protein phosphatase 7", "gene_name": "DUSP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28562-1", "protein_name": "Dual specificity protein phosphatase 1", "gene_name": "DUSP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05923-1", "protein_name": "Dual 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mitotic inhibition of GRASP65 organelle tethering involves Polo-like kinase 1 (PLK1) phosphorylation proximate to an internal PDZ ligand.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Sengupta D, Linstedt AD", "reference": { "type": "PubMed", "id": "20937827", "url": "https://pubmed.ncbi.nlm.nih.gov/20937827" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P28482-1", "protein_name": "Mitogen-activated protein kinase 1", "gene_name": "MAPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53350-1", "protein_name": "Serine/threonine-protein kinase PLK1", "gene_name": "PLK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06493-1", "protein_name": "Cyclin-dependent kinase 1", "gene_name": "CDK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0U4-1", "protein_name": "Ras-related 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