[ { "title": "The human cytomegalovirus UL36 gene controls caspase-dependent and -independent cell death programs activated by infection of monocytes differentiating to macrophages.", "journal": "Journal of virology", "date": "2010", "authors": "McCormick AL, Roback L, Livingston-Rosanoff D, St Clair C", "reference": { "type": "PubMed", "id": "20219915", "url": "https://pubmed.ncbi.nlm.nih.gov/20219915" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase 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"protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20219915", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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targeting TBK1-IKKi kinases.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Parvatiyar K, Barber GN, Harhaj EW", "reference": { "type": "PubMed", "id": "20304918", "url": "https://pubmed.ncbi.nlm.nih.gov/20304918" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EQ8-1", "protein_name": "E3 ubiquitin-protein ligase RNF125", "gene_name": "RNF125", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WI3-1", "protein_name": "Protein NLRC5", "gene_name": "NLRC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41226-1", "protein_name": "Ubiquitin-like modifier-activating enzyme 7", "gene_name": "UBA7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C037-1", "protein_name": "E3 ubiquitin-protein ligase TRIM4", "gene_name": "TRIM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H1Y0-1", "protein_name": "Autophagy protein 5", "gene_name": "ATG5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUD6-1", "protein_name": "E3 ubiquitin-protein ligase RNF135", "gene_name": "RNF135", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes: affinity, specificity, and regulation.", "journal": "Molecular cell", "date": "2010", "authors": "Zheng C, Kabaleeswaran V, Wang Y, Cheng G, Wu H", "reference": { "type": "PubMed", "id": "20385093", "url": "https://pubmed.ncbi.nlm.nih.gov/20385093" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15750-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1", "gene_name": "TAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", 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"gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N5C8-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3", "gene_name": "TAB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYJ8-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2", "gene_name": "TAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hepatitis B virus polymerase blocks pattern recognition receptor signaling via interaction with DDX3: implications for immune evasion.", "journal": "PLoS Pathog.", "date": "2010", "authors": "Wang Haifeng, Ryu Wang-Shick", "reference": { "type": "PubMed", "id": "20657822", "url": "https://pubmed.ncbi.nlm.nih.gov/20657822" }, "referenced_glycans": [], "referenced_proteins": [ { 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"protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 177, "end_pos": 177, "kinase_uniprot_canonical_ac": "Q9UHD2-1", "kinase_gene_name": "TBK1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q96CV9", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q96CV9" }, { "database": "PubMed", "id": "18307994", "url": "https://pubmed.ncbi.nlm.nih.gov/18307994" }, { "database": "PubMed", "id": "21617041", "url": "https://pubmed.ncbi.nlm.nih.gov/21617041" }, { "database": "PubMed", "id": "21862579", "url": "https://pubmed.ncbi.nlm.nih.gov/21862579" } ], "site_lbl": "Ser177", "uniprot_canonical_ac": "Q96CV9-1" } ], "record_id": 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"kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The SARS-coronavirus-host interactome: identification of cyclophilins as target for pan-coronavirus inhibitors.", "journal": "PLoS pathogens", "date": "2011", "authors": "Pfefferle S, Schopf J, Kogl M, Friedel CC, Muller MA, Carbajo-Lozoya J, Stellberger T, von Dall'Armi E, Herzog P, Kallies S, Niemeyer D, Ditt V, Kuri T, Zust R, Pumpor K, Hilgenfeld R, Schwarz F, Zimmer R, Steffen I, Weber F, Thiel V, Herrler G, Thiel HJ, Schwegmann-Wessels C, Pohlmann S, Haas J, Drosten C, von Brunn A", "reference": { "type": "PubMed", "id": "22046132", "url": "https://pubmed.ncbi.nlm.nih.gov/22046132" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase 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{ "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22179575", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SARS coronavirus 3b accessory protein modulates transcriptional activity of RUNX1b.", "journal": "PloS one", "date": "2012", "authors": "Varshney B, Agnihothram S, Tan YJ, Baric R, Lal SK", "reference": { "type": "PubMed", "id": "22253733", "url": "https://pubmed.ncbi.nlm.nih.gov/22253733" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59633-1", "protein_name": "ORF3b protein", "gene_name": "3b", "tax_name": "SARS-CoV" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22253733", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CLIPR-59 regulates TNF-alpha-induced apoptosis by controlling ubiquitination of RIP1.", "journal": "Cell death & disease", "date": "2012", "authors": "Fujikura D, Ito M, Chiba S, Harada T, Perez F, Reed JC, Uede T, Miyazaki T", "reference": { "type": "PubMed", "id": "22297296", "url": "https://pubmed.ncbi.nlm.nih.gov/22297296" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22297296", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Coronavirus papain-like proteases negatively regulate antiviral innate immune response through disruption of STING-mediated signaling.", "journal": "PloS one", "date": "2012", "authors": "Sun L, Xing Y, Chen X, Zheng Y, Yang Y, Nichols DB, Clementz MA, Banach BS, Li K, Baker SC, Chen Z", "reference": { "type": "PubMed", "id": "22312431", "url": "https://pubmed.ncbi.nlm.nih.gov/22312431" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22312431", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of NF-kappaB by deubiquitinases.", "journal": "Immunological reviews", "date": "2012", "authors": "Harhaj EW, Dixit VM", "reference": { "type": "PubMed", "id": "22435550", "url": "https://pubmed.ncbi.nlm.nih.gov/22435550" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", 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linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": 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"Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22435550", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "NEMO inhibits programmed necrosis in an NFkappaB-independent manner by restraining RIP1.", "journal": "PloS one", "date": "2012", "authors": "O'Donnell MA, Hase H, Legarda D, Ting AT", "reference": { "type": "PubMed", "id": "22848449", "url": "https://pubmed.ncbi.nlm.nih.gov/22848449" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 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"gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": 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"Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": 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"gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": 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"Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23313255", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99836-1", "protein_name": "Myeloid differentiation primary response protein MyD88", "gene_name": "MYD88", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XR7-1", "protein_name": "TIR domain-containing adapter molecule 2", "gene_name": "TICAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUC6-1", "protein_name": "TIR domain-containing adapter molecule 1", "gene_name": "TICAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 30, "end_pos": 30, "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of ubiquitination and decreased kinase activity. No effect on homodimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" }, { "database": "PubMed", "id": "23453969", "url": "https://pubmed.ncbi.nlm.nih.gov/23453969" } ], "uniprot_canonical_ac": "Q14164-1" }, { "start_pos": 30, "end_pos": 30, "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of ubiquitination and decreased kinase activity. Decreases interaction with IKBKB, IKBKG and MYD88. No effect on homodimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" }, { "database": "PubMed", "id": "23453969", "url": "https://pubmed.ncbi.nlm.nih.gov/23453969" } ], "uniprot_canonical_ac": "Q14164-1" }, { "start_pos": 401, "end_pos": 401, "sequence_org": "K", "sequence_mut": "A", "comment": "Loss of ubiquitination and decreased kinase activity. No effect on homodimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" }, { "database": "PubMed", "id": "23453969", "url": "https://pubmed.ncbi.nlm.nih.gov/23453969" } ], "uniprot_canonical_ac": "Q14164-1" }, { "start_pos": 401, "end_pos": 401, "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of ubiquitination and decreased kinase activity. Decreases interaction with IKBKB, IKBKG and MYD88. No effect on homodimerization.", "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" }, { "database": "PubMed", "id": "23453969", "url": "https://pubmed.ncbi.nlm.nih.gov/23453969" } ], "uniprot_canonical_ac": "Q14164-1" }, { "start_pos": 416, "end_pos": 416, "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on ubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" }, { "database": "PubMed", "id": "23453969", "url": "https://pubmed.ncbi.nlm.nih.gov/23453969" } ], "uniprot_canonical_ac": "Q14164-1" }, { "start_pos": 416, "end_pos": 416, "sequence_org": "K", "sequence_mut": "R", "comment": "No effect on ubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" }, { "database": "PubMed", "id": "23453969", "url": "https://pubmed.ncbi.nlm.nih.gov/23453969" } ], "uniprot_canonical_ac": 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"sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure and ubiquitination-dependent activation of TANK-binding kinase 1.", "journal": "Cell reports", "date": "2013", "authors": "Tu D, Zhu Z, Zhou AY, Yun CH, Lee KE, Toms AV, Li Y, Dunn GP, Chan E, Thai 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No effect on interaction with IKBKE.", "evidence": [ { "database": "UniProtKB", "id": "O00571", "url": "https://www.uniprot.org/uniprotkb/O00571" }, { "database": "PubMed", "id": "23478265", "url": "https://pubmed.ncbi.nlm.nih.gov/23478265" } ], "uniprot_canonical_ac": "O00571-1" }, { "start_pos": 71, "end_pos": 71, "sequence_org": "S", "sequence_mut": "A", "comment": "Reduces total phosphorylation by 60%. No effect on interaction with IKBKE.", "evidence": [ { "database": "UniProtKB", "id": "O00571", "url": "https://www.uniprot.org/uniprotkb/O00571" }, { "database": "PubMed", "id": "23478265", "url": "https://pubmed.ncbi.nlm.nih.gov/23478265" } ], "uniprot_canonical_ac": "O00571-1" }, { "start_pos": 82, "end_pos": 83, "sequence_org": "SS", "sequence_mut": "AA", "comment": "Reduces total phosphorylation by 50%. No effect on interaction with IKBKE.", "evidence": [ { "database": "UniProtKB", "id": "O00571", "url": "https://www.uniprot.org/uniprotkb/O00571" }, { "database": "PubMed", "id": "23478265", "url": "https://pubmed.ncbi.nlm.nih.gov/23478265" } ], "uniprot_canonical_ac": "O00571-1" } ], "record_id": "pubmed.23478265", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Assembling an ion channel: ORF 3a from SARS-CoV.", "journal": "Biopolymers", "date": "2013", "authors": "Chien TH, Chiang YL, Chen CP, Henklein P, Hanel K, Hwang IS, Willbold D, Fischer WB", "reference": { "type": "PubMed", "id": "23483519", "url": "https://pubmed.ncbi.nlm.nih.gov/23483519" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": 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"gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23483519", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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}, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor 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pathway via NS2B/3 protease-IkappaB kinase epsilon interaction.", "journal": "Clinical and vaccine immunology : CVI", "date": "2014", "authors": "Anglero-Rodriguez YI, Pantoja P, Sariol CA", "reference": { "type": "PubMed", "id": "24173023", "url": "https://pubmed.ncbi.nlm.nih.gov/24173023" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10909-1", "protein_name": "Clusterin", "gene_name": "CLU", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11226-1", "protein_name": "Mannose-binding protein C", "gene_name": "MBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY25-1", "protein_name": "C-type lectin domain family 5 member A", "gene_name": "CLEC5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N7H5-1", "protein_name": "RNA polymerase II-associated factor 1 homolog", "gene_name": "PAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PD62-1", "protein_name": "RNA polymerase-associated protein CTR9 homolog", "gene_name": "CTR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVC0-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92541-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "RTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09871-1", "protein_name": "Complement C1s subcomponent", "gene_name": "C1S", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04003-1", "protein_name": "C4b-binding protein alpha chain", "gene_name": "C4BPA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20851-1", "protein_name": "C4b-binding protein beta chain", "gene_name": "C4BPB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C0L5-1", "protein_name": "Complement C4-B", "gene_name": "C4B_2; C4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C0L4-1", "protein_name": "Complement C4-A", "gene_name": "C4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52630-3", "protein_name": "Signal transducer and activator of transcription 2", "gene_name": "STAT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08238-1", "protein_name": "Heat shock protein HSP 90-beta", "gene_name": "HSP90AB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98175-1", "protein_name": "RNA-binding protein 10", "gene_name": "RBM10", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00571-1", "protein_name": "ATP-dependent RNA helicase DDX3X", "gene_name": "DDX3X", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZS3-1", "protein_name": "Superkiller complex protein 8", "gene_name": "SKIC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6P1J9-1", "protein_name": "Parafibromin", "gene_name": "CDC73", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02745-1", "protein_name": "Complement C1q subcomponent subunit A", "gene_name": "C1QA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04004-1", "protein_name": "Vitronectin", "gene_name": "VTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5T4S7-1", "protein_name": "E3 ubiquitin-protein ligase UBR4", "gene_name": "UBR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N884-1", "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "CGAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NV70-1", "protein_name": "Exocyst complex component 1", "gene_name": "EXOC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02647-1", "protein_name": "Apolipoprotein A-I", "gene_name": "APOA1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24173023", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 30 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A20 in inflammation and autoimmunity.", "journal": "Trends in immunology", "date": "2014", "authors": "Catrysse L, Vereecke L, Beyaert R, van Loo G", "reference": { "type": "PubMed", "id": "24246475", "url": "https://pubmed.ncbi.nlm.nih.gov/24246475" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein 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domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24246475", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RACK1 modulates NF-kappaB activation by interfering with the interaction between TRAF2 and the IKK complex.", "journal": "Cell research", "date": "2014", "authors": "Yao F, Long LY, Deng YZ, Feng YY, Ying GY, Bao WD, Li G, Guan DX, Zhu YQ, Li JJ, Xie D", "reference": { "type": "PubMed", "id": "24323043", "url": "https://pubmed.ncbi.nlm.nih.gov/24323043" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24323043", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain.", "journal": "Cellular & molecular immunology", "date": "2014", "authors": "Siu KL, Chan CP, Kok KH, Chiu-Yat Woo P, Jin DY", "reference": { "type": "PubMed", "id": "24509444", "url": "https://pubmed.ncbi.nlm.nih.gov/24509444" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24509444", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SARS coronavirus papain-like protease inhibits the type I interferon signaling pathway through interaction with the STING-TRAF3-TBK1 complex.", "journal": "Protein & cell", "date": "2014", "authors": "Chen X, Yang X, Zheng Y, Yang Y, Xing Y, Chen Z", "reference": { "type": "PubMed", "id": "24622840", "url": "https://pubmed.ncbi.nlm.nih.gov/24622840" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { 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"protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C6U8-1", "protein_name": "Replicase polyprotein 1a", "gene_name": "1a", "tax_name": "SARS-CoV" }, { "uniprot_canonical_ac": "P0C6X7-1", "protein_name": "Replicase polyprotein 1ab", "gene_name": "rep", "tax_name": "SARS-CoV" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": 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Mol. Cell Biol.", "date": "2014", "authors": "Ning Yun-Jia, Wang Manli, Deng Maping, Shen Shu, Liu Wei, Cao Wu-Chun, Deng Fei, Wang Yan-Yi, Hu Zhihong, Wang Hualin", "reference": { "type": "PubMed", "id": "24706939", "url": "https://pubmed.ncbi.nlm.nih.gov/24706939" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24706939", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Binding of OTULIN to the PUB domain of HOIP controls NF-kappaB signaling.", "journal": "Molecular cell", "date": "2014", "authors": "Schaeffer V, Akutsu M, Olma MH, Gomes LC, Kawasaki M, Dikic I", "reference": { "type": "PubMed", "id": "24726327", "url": "https://pubmed.ncbi.nlm.nih.gov/24726327" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating activity of SARS-CoV papain-like protease.", "journal": "PLoS pathogens", "date": "2014", "authors": "Ratia K, Kilianski A, Baez-Santos YM, Baker SC, Mesecar A", "reference": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKKepsilon kinase-mediated antiviral response.", "journal": "Immunity", "date": "2014", "authors": "Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martinez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, Garcia-Sastre A", "reference": { "type": "PubMed", "id": "24882218", "url": "https://pubmed.ncbi.nlm.nih.gov/24882218" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8BGE7-1", "protein_name": "Tripartite motif-containing protein 6", "gene_name": "Trim6", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C030-1", "protein_name": "Tripartite motif-containing protein 6", "gene_name": "TRIM6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": 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}, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SARS-coronavirus open reading frame-9b suppresses innate immunity by targeting mitochondria and the MAVS/TRAF3/TRAF6 signalosome.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2014", "authors": "Shi CS, Qi HY, Boularan C, Huang NN, Abu-Asab M, Shelhamer JH, Kehrl JH", "reference": { "type": "PubMed", "id": "25135833", "url": "https://pubmed.ncbi.nlm.nih.gov/25135833" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14457-1", "protein_name": "Beclin-1", "gene_name": "BECN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99570-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 4", "gene_name": "PIK3R4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P2Y5-1", "protein_name": "UV radiation resistance-associated gene protein", "gene_name": "UVRAG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZQ8-1", "protein_name": "Microtubule-associated protein 1 light chain 3 beta", "gene_name": "MAP1LC3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEB9-1", "protein_name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "gene_name": "PIK3C3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59636-1", "protein_name": "ORF9b protein", "gene_name": "9b", "tax_name": "SARS-CoV" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25135833", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 55 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The cylindromatosis gene product, CYLD, interacts with MIB2 to regulate notch signalling.", "journal": "Oncotarget", "date": "2014", "authors": "Rajan N, Elliott RJ, Smith A, Sinclair N, Swift S, Lord CJ, Ashworth A", "reference": { "type": "PubMed", "id": "25565632", "url": "https://pubmed.ncbi.nlm.nih.gov/25565632" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25565632", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SARS hCoV papain-like protease is a unique Lys48 linkage-specific di-distributive deubiquitinating enzyme.", "journal": "The Biochemical journal", "date": "2015", "authors": "Bekes M, Rut W, Kasperkiewicz P, Mulder MP, Ovaa H, Drag M, Lima CD, Huang TT", "reference": { "type": "PubMed", "id": "25764917", "url": "https://pubmed.ncbi.nlm.nih.gov/25764917" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25764917", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Severe acute respiratory syndrome coronavirus protein 6 mediates ubiquitin-dependent proteosomal degradation of N-Myc (and STAT) interactor.", "journal": "Virologica Sinica", "date": "2015", "authors": "Cheng W, Chen S, Li R, Chen Y, Wang M, Guo D", "reference": { "type": "PubMed", "id": "25907116", "url": "https://pubmed.ncbi.nlm.nih.gov/25907116" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25907116", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phage display technique identifies the interaction of severe acute respiratory syndrome coronavirus open reading frame 6 protein with nuclear pore complex interacting protein NPIPB3 in modulating Type I interferon antagonism.", "journal": "Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi", "date": "2017", "authors": "Huang SH, Lee TY, Lin YJ, Wan L, Lai CH, Lin CW", "reference": { "type": "PubMed", "id": "26320399", "url": "https://pubmed.ncbi.nlm.nih.gov/26320399" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" 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"P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like 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"gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26320399", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "NF-kappaB-Independent Role of IKKalpha/IKKbeta in Preventing RIPK1 Kinase-Dependent Apoptotic and Necroptotic Cell Death during TNF Signaling.", "journal": "Molecular cell", "date": "2015", "authors": "Dondelinger Y, Jouan-Lanhouet S, Divert T, Theatre E, Bertin J, Gough PJ, Giansanti P, Heck AJ, Dejardin E, Vandenabeele P, Bertrand MJ", "reference": { "type": "PubMed", "id": "26344099", "url": 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"uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26344099", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference.", "journal": "Journal of virology", "date": "2015", "authors": "Taylor JK, Coleman CM, Postel S, Sisk JM, Bernbaum JG, Venkataraman T, Sundberg EJ, Frieman MB", "reference": { "type": "PubMed", "id": "26378163", "url": 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homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P59635-1", "protein_name": "ORF7a protein", "gene_name": "7a", "tax_name": "SARS-CoV" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26378163", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune Signaling.", "journal": "Cell reports", "date": "2016", "authors": "Hrdinka M, Fiil BK, Zucca M, Leske D, Bagola K, Yabal M, Elliott PR, Damgaard RB, Komander D, Jost PJ, Gyrd-Hansen M", "reference": { "type": "PubMed", "id": "26997266", "url": "https://pubmed.ncbi.nlm.nih.gov/26997266" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SARS Coronavirus Papain-Like Protease Inhibits the TLR7 Signaling Pathway through Removing Lys63-Linked Polyubiquitination of TRAF3 and TRAF6.", "journal": "International journal of molecular sciences", "date": "2016", "authors": "Li SW, Wang CY, Jou YJ, Huang SH, Hsiao LH, Wan L, Lin YJ, Kung SH, Lin CW", "reference": { "type": "PubMed", "id": "27164085", "url": "https://pubmed.ncbi.nlm.nih.gov/27164085" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27164085", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.", "journal": "Molecular cell", "date": "2016", "authors": "Bekes M, van der Heden van Noort GJ, Ekkebus R, Ovaa H, Huang TT, Lima CD", "reference": { "type": "PubMed", "id": "27203180", "url": "https://pubmed.ncbi.nlm.nih.gov/27203180" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKA8-1", "protein_name": "Calcipressin-3", "gene_name": "RCAN3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13427-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase G", "gene_name": "PPIG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15366-1", "protein_name": "Poly(rC)-binding protein 2", "gene_name": "PCBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62942-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP1A", "gene_name": "FKBP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27203180", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IKBKE Is a Substrate of EGFR and a Therapeutic Target in Non-Small Cell Lung Cancer with Activating Mutations of EGFR.", "journal": "Cancer research", "date": "2016", "authors": "Challa S, Guo JP, Ding X, Xu CX, Li Y, Kim D, Smith MA, Cress DW, Coppola D, Haura EB, Cheng JQ", "reference": { "type": "PubMed", "id": "27287717", "url": "https://pubmed.ncbi.nlm.nih.gov/27287717" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 153, "end_pos": 153, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14164" }, { "database": "PubMed", "id": "27287717", "url": "https://pubmed.ncbi.nlm.nih.gov/27287717" } ], "site_lbl": "Tyr153", "uniprot_canonical_ac": "Q14164-1" }, { "start_pos": 179, "end_pos": 179, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q14164", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q14164" }, { "database": "PubMed", "id": "27287717", "url": "https://pubmed.ncbi.nlm.nih.gov/27287717" } ], "site_lbl": "Tyr179", "uniprot_canonical_ac": "Q14164-1" } ], 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"end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SPATA2 links CYLD to the TNF-alpha receptor signaling complex and modulates the receptor signaling outcomes.", "journal": "The EMBO journal", "date": "2016", "authors": "Wagner SA, Satpathy S, Beli P, Choudhary C", "reference": { "type": "PubMed", "id": "27307491", "url": "https://pubmed.ncbi.nlm.nih.gov/27307491" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27307491", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SPATA2 promotes CYLD activity and regulates TNF-induced NF-kappaB signaling and cell death.", "journal": "EMBO reports", "date": "2016", "authors": "Schlicher L, Wissler M, Preiss F, Brauns-Schubert P, Jakob C, Dumit V, Borner C, Dengjel J, Maurer U", "reference": { "type": "PubMed", "id": "27458237", "url": "https://pubmed.ncbi.nlm.nih.gov/27458237" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { 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"gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8K004-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "Spata2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27545878", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 47 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Linear ubiquitination is involved in the pathogenesis of optineurin-associated amyotrophic lateral sclerosis.", "journal": "Nature communications", "date": "2016-08-24", "authors": "Nakazawa Seshiru, Oikawa Daisuke, Ishii Ryohei, Ayaki Takashi, Takahashi Hirotaka, Takeda Hiroyuki, Ishitani Ryuichiro, Kamei Kiyoko, Takeyoshi Izumi, Kawakami Hideshi, Iwai Kazuhiro, Hatada Izuho, Sawasaki Tatsuya, Ito Hidefumi, Nureki Osamu, Tokunaga Fuminori", "reference": { "type": "PubMed", "id": "27552911", "url": "https://pubmed.ncbi.nlm.nih.gov/27552911" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27552911", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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Cell Death.", "journal": "Molecular cell", "date": "2017", "authors": "Jaco I, Annibaldi A, Lalaoui N, Wilson R, Tenev T, Laurien L, Kim C, Jamal K, Wicky John S, Liccardi G, Chau D, Murphy JM, Brumatti G, Feltham R, Pasparakis M, Silke J, Meier P", "reference": { "type": "PubMed", "id": "28506461", "url": "https://pubmed.ncbi.nlm.nih.gov/28506461" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { 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"title": "Association of rs1285933 single nucleotide polymorphism in CLEC5A gene with dengue severity and its functional effects.", "journal": "Human immunology", "date": "2017", "authors": "Xavier-Carvalho C, Cezar RDDS, Freire NM, Vasconcelos CMM, Solorzano VEF, de Toledo-Pinto TG, Fialho LG, do Carmo RF, Vasconcelos LRS, Cordeiro MT, Baptista P, de Azeredo EL, da Cunha RV, de Souza LJ, Pacheco AG, Kubelka CF, Moura PMMF, Moraes MO", "reference": { "type": "PubMed", "id": "28764923", "url": "https://pubmed.ncbi.nlm.nih.gov/28764923" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10909-1", "protein_name": "Clusterin", "gene_name": "CLU", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": 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{ "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential.", "journal": "Cell reports", "date": "2018", "authors": "Feltham R, Jamal K, Tenev T, Liccardi G, Jaco I, Domingues CM, Morris O, John SW, Annibaldi A, Widya M, Kearney CJ, Clancy D, Elliott PR, Glatter T, Qiao Q, Thompson AJ, Nesvizhskii A, Schmidt A, Komander D, Wu H, Martin S, Meier P", "reference": { "type": "PubMed", "id": "29642005", "url": "https://pubmed.ncbi.nlm.nih.gov/29642005" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.", "journal": "Cell", "date": "2018", "authors": "Xu D, Jin T, Zhu H, Chen H, Ofengeim D, Zou C, Mifflin L, Pan L, Amin P, Li W, Shan B, Naito MG, Meng H, Li Y, Pan H, Aron L, Adiconis X, Levin JZ, Yankner BA, Yuan J", "reference": { "type": "PubMed", "id": "30146158", "url": "https://pubmed.ncbi.nlm.nih.gov/30146158" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated 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"gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SARS-Coronavirus Open Reading Frame-3a drives multimodal necrotic cell death.", "journal": "Cell death & disease", "date": "2018", "authors": "Yue Y, Nabar NR, Shi CS, Kamenyeva O, Xiao X, Hwang IY, Wang M, Kehrl JH", "reference": { "type": "PubMed", "id": "30185776", "url": "https://pubmed.ncbi.nlm.nih.gov/30185776" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULZ3-1", "protein_name": "Apoptosis-associated speck-like protein containing a CARD", "gene_name": "PYCARD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting 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}, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96J02-1", "protein_name": "E3 ubiquitin-protein ligase Itchy homolog", "gene_name": "ITCH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01196-1", "protein_name": "Runt-related transcription factor 1", "gene_name": "RUNX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92617-1", "protein_name": "Nuclear pore complex-interacting protein family member B3", "gene_name": "NPIPB3", "tax_name": 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"protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": "RIPK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q10589-1", "protein_name": "Bone marrow stromal antigen 2", "gene_name": "BST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFalpha-induced apoptosis.", "journal": "The Journal of biological chemistry", "date": "2018", "authors": "Tang Y, Joo D, Liu G, Tu H, You J, Jin J, Zhao X, Hung MC, Lin X", "reference": { "type": "PubMed", "id": "30361438", "url": "https://pubmed.ncbi.nlm.nih.gov/30361438" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor 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"gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.30361438", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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II-associated factor 1 homolog", "gene_name": "PAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PD62-1", "protein_name": "RNA polymerase-associated protein CTR9 homolog", "gene_name": "CTR9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVC0-1", "protein_name": "RNA polymerase-associated protein LEO1", "gene_name": "LEO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92541-1", "protein_name": "RNA polymerase-associated protein RTF1 homolog", "gene_name": "RTF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09871-1", "protein_name": "Complement C1s subcomponent", "gene_name": "C1S", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04003-1", "protein_name": "C4b-binding protein alpha chain", "gene_name": "C4BPA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20851-1", "protein_name": "C4b-binding protein beta chain", "gene_name": "C4BPB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C0L5-1", "protein_name": "Complement C4-B", "gene_name": "C4B_2; C4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C0L4-1", "protein_name": "Complement C4-A", "gene_name": "C4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52630-3", "protein_name": "Signal transducer and activator of transcription 2", "gene_name": "STAT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08238-1", "protein_name": "Heat shock protein HSP 90-beta", "gene_name": "HSP90AB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98175-1", "protein_name": "RNA-binding protein 10", "gene_name": "RBM10", "tax_name": "Human" }, { 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Larvae initially have normal brain sizes, but later in the third larval stage, the brain is smaller than in wild-type counterparts.", "evidence": [ { "database": "UniProtKB", "id": "Q8MQX9", "url": "https://www.uniprot.org/uniprotkb/Q8MQX9" }, { "database": "PubMed", "id": "30550790", "url": "https://pubmed.ncbi.nlm.nih.gov/30550790" }, { "database": "PubMed", "id": "25259927", "url": "https://pubmed.ncbi.nlm.nih.gov/25259927" } ], "uniprot_canonical_ac": "Q8MQX9-1" } ], "record_id": "pubmed.30550790", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 34 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"field": "total", "count": 41 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"MAP1LC3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEB9-1", "protein_name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "gene_name": "PIK3C3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase B", "gene_name": "PPIB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13287-1", "protein_name": "N-myc-interactor", "gene_name": "NMI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y572-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 3", "gene_name": 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"uniprot_canonical_ac": "O43447-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase H", "gene_name": "PPIH", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14974-1", "protein_name": "Importin subunit beta-1", "gene_name": "KPNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.31231549", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 54 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", 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Stuhler K, Tschapek A, Godecke A, Stork B", "reference": { "type": "PubMed", "id": "32320653", "url": "https://pubmed.ncbi.nlm.nih.gov/32320653" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Linear Ubiquitination of RIPK1 on Lys612 Regulates Systemic Inflammation via Preventing Cell Death.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2021", "authors": "Tu H, Tang Y, Zhang J, Cheng L, Joo D, Zhao X, Lin X", "reference": { "type": "PubMed", "id": "34162724", "url": "https://pubmed.ncbi.nlm.nih.gov/34162724" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit 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"Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 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"uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34162724", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human TBK1 deficiency leads to autoinflammation driven by TNF-induced cell death.", "journal": "Cell", "date": "2021", "authors": "Taft J, Markson M, Legarda D, Patel R, Chan M, Malle L, Richardson A, Gruber C, Martin-Fernandez M, Mancini GMS, van Laar JAM, van Pelt P, Buta S, Wokke BHA, Sabli IKD, Sancho-Shimizu V, Chavan PP, Schnappauf O, Khubchandani R, Cuceoglu MK, Ozen S, Kastner DL, Ting AT, Aksentijevich I, Hollink IHIM, Bogunovic D", "reference": { "type": "PubMed", "id": "34363755", "url": "https://pubmed.ncbi.nlm.nih.gov/34363755" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "OTUD1 deubiquitinase regulates NF-kappaB- and KEAP1-mediated inflammatory responses and reactive oxygen species-associated cell death pathways.", "journal": "Cell death & disease", "date": "2022", "authors": "Oikawa D, Gi M, Kosako H, Shimizu K, Takahashi H, Shiota M, Hosomi S, Komakura K, Wanibuchi H, Tsuruta D, Sawasaki T, Tokunaga F", "reference": { "type": "PubMed", "id": "35941131", "url": "https://pubmed.ncbi.nlm.nih.gov/35941131" }, "referenced_glycans": [], "referenced_proteins": [ { 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"Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": 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{ "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Increased IKK\u03f5 protein stability ensures efficient type I interferon responses in conditions of TBK1 deficiency.", "journal": "Frontiers in immunology", "date": "2023", "authors": "Wegner Julia, Hunkler Charlotte, Ciupka Katrin, Hartmann Gunther, Schlee Martin", "reference": { "type": "PubMed", "id": "36936901", "url": "https://pubmed.ncbi.nlm.nih.gov/36936901" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit 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"uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUC6-1", "protein_name": "TIR domain-containing adapter molecule 1", "gene_name": "TICAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36936901", "abstract": "", "glycosylation": [], 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Exploring the Roles of Key Mediators IKBKE and HSPA1A in Alzheimer's Disease and Hepatocellular Carcinoma through Bioinformatics Analysis.", "journal": "International journal of molecular sciences", "date": "2024-06-25", "authors": "Wang Yiying, Yang Yakun, Liang Ce, Zhang Hailin", "reference": { "type": "PubMed", "id": "39000042", "url": "https://pubmed.ncbi.nlm.nih.gov/39000042" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DMV8-1", "protein_name": "Heat shock 70 kDa 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fas- and tumor necrosis factor-induced apoptosis is inhibited by the poxvirus crmA gene product.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Tewari M, Dixit VM", "reference": { "type": "PubMed", "id": "7531702", "url": "https://pubmed.ncbi.nlm.nih.gov/7531702" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 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"protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide 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"gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7531702", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Tumor necrosis factor-induced apoptosis is mediated by a CrmA-sensitive cell death pathway.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1995", "authors": "Miura M, Friedlander RM, Yuan J", "reference": { "type": "PubMed", "id": "7667287", "url": "https://pubmed.ncbi.nlm.nih.gov/7667287" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7667287", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Vaccinia virus serpin B13R (SPI-2) inhibits interleukin-1beta-converting enzyme and protects virus-infected cells from TNF- and Fas-mediated apoptosis, but does not prevent IL-1beta-induced fever.", "journal": "The Journal of general virology", "date": "1997", "authors": "Kettle S, Alcami A, Khanna A, Ehret R, Jassoy C, Smith GL", "reference": { "type": "PubMed", "id": "9049422", "url": "https://pubmed.ncbi.nlm.nih.gov/9049422" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9049422", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Target protease specificity of the viral serpin CrmA. Analysis of five caspases.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Zhou Q, Snipas S, Orth K, Muzio M, Dixit VM, Salvesen GS", "reference": { "type": "PubMed", "id": "9065443", "url": "https://pubmed.ncbi.nlm.nih.gov/9065443" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P98170-1", "protein_name": "E3 ubiquitin-protein ligase XIAP", "gene_name": "XIAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13546-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 1", "gene_name": "RIPK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75385-1", "protein_name": "Serine/threonine-protein kinase ULK1", "gene_name": "ULK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21580-1", "protein_name": "Tumor necrosis factor alpha-induced protein 3", "gene_name": "TNFAIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96DZ5-1", "protein_name": "CAP-Gly domain-containing linker protein 3", "gene_name": "CLIP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19438-1", "protein_name": "Tumor necrosis factor receptor superfamily member 1A", "gene_name": "TNFRSF1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UM82-1", "protein_name": "Spermatogenesis-associated protein 2", "gene_name": "SPATA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49137-1", "protein_name": "MAP kinase-activated protein kinase 2", "gene_name": "MAPKAPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYM8-1", "protein_name": "RanBP-type and C3HC4-type zinc finger-containing protein 1", "gene_name": "RBCK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EP0-1", "protein_name": "E3 ubiquitin-protein ligase RNF31", "gene_name": "RNF31", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H0F6-1", "protein_name": "Sharpin", "gene_name": "SHARPIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VV17-1", "protein_name": "OTU domain-containing protein 1", "gene_name": "OTUD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96AX9-1", "protein_name": "E3 ubiquitin-protein ligase MIB2", "gene_name": "MIB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT8-1", "protein_name": "Signal peptide peptidase-like 2A", "gene_name": "SPPL2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61077-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D3", "gene_name": "UBE2D3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VP1-1", "protein_name": "Tax1-binding protein 1", "gene_name": "TAX1BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13158-1", "protein_name": "FAS-associated death domain protein", "gene_name": "FADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6GQQ9-1", "protein_name": "OTU domain-containing protein 7B", "gene_name": "OTUD7B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQC7-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD", "gene_name": "CYLD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK80-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21", "gene_name": "USP21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TCT7-1", "protein_name": "Signal peptide peptidase-like 2B", "gene_name": "SPPL2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13077-1", "protein_name": "TNF receptor-associated factor 1", "gene_name": "TRAF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14790-1", "protein_name": "Caspase-8", "gene_name": "CASP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15628-1", "protein_name": "Tumor necrosis factor receptor type 1-associated DEATH domain protein", "gene_name": "TRADD", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13490-1", "protein_name": "Baculoviral IAP repeat-containing protein 2", "gene_name": "BIRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13489-1", "protein_name": "Baculoviral IAP repeat-containing protein 3", "gene_name": "BIRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01375-1", "protein_name": "Tumor necrosis factor", "gene_name": "TNF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96BN8-1", "protein_name": "Ubiquitin thioesterase otulin", "gene_name": "OTULIN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12933-1", "protein_name": "TNF receptor-associated factor 2", "gene_name": "TRAF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13107-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4", "gene_name": "USP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63244-1", "protein_name": "Small ribosomal subunit protein RACK1", "gene_name": "RACK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75604-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2", "gene_name": "USP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9065443", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Virus-dependent phosphorylation of the IRF-3 transcription factor regulates nuclear translocation, transactivation potential, and proteasome-mediated degradation.", "journal": "Molecular and cellular biology", "date": "1998", "authors": "Lin R, Heylbroeck C, Pitha PM, Hiscott J", "reference": { "type": "PubMed", "id": "9566918", "url": "https://pubmed.ncbi.nlm.nih.gov/9566918" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92844-1", "protein_name": "TRAF family member-associated NF-kappa-B activator", "gene_name": "TANK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "GEC1 interacts with the kappa opioid receptor and enhances expression of the receptor.", "journal": "The Journal of biological chemistry", "date": "2006-03-24", "authors": "Chen Chongguang, Li Jian-Guo, Chen Yong, Huang Peng, Wang Yulin, Liu-Chen Lee-Yuan", "reference": { "type": "PubMed", "id": "16431922", "url": "https://pubmed.ncbi.nlm.nih.gov/16431922" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0R8-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 1", "gene_name": "GABARAPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41145-1", "protein_name": "Kappa-type opioid receptor", "gene_name": "OPRK1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H0R8", "url": "https://www.uniprot.org/uniprotkb/Q9H0R8" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16431922", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "p62/SQSTM1 binds directly to Atg8/LC3 to facilitate degradation of ubiquitinated protein aggregates by autophagy.", "journal": "J. Biol. Chem.", "date": "2007", "authors": "Pankiv S, Clausen TH, Lamark T, Brech A, Bruun JA, Outzen H, Overvatn A, Bjorkoy G, Johansen T", "reference": { "type": "PubMed", "id": "17580304", "url": "https://pubmed.ncbi.nlm.nih.gov/17580304" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0R8-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 1", "gene_name": "GABARAPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95166-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein", "gene_name": "GABARAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H492-1", "protein_name": "Microtubule-associated protein 1 light chain 3 alpha", "gene_name": "MAP1LC3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99814-1", "protein_name": "Endothelial PAS domain-containing protein 1", "gene_name": "EPAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14596-1", "protein_name": "Next to BRCA1 gene 1 protein", 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{ "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Network organization of the human autophagy system.", "journal": "Nature", "date": "2010", "authors": "Behrends C, Sowa ME, Gygi SP, Harper JW", "reference": { "type": "PubMed", "id": "20562859", "url": "https://pubmed.ncbi.nlm.nih.gov/20562859" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0R8-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 1", "gene_name": "GABARAPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95166-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein", "gene_name": "GABARAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEV9-1", "protein_name": "Guanine nucleotide exchange protein SMCR8", "gene_name": "SMCR8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15040-1", "protein_name": "Tectonin beta-propeller repeat-containing protein 2", "gene_name": "TECPR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60520-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "gene_name": "GABARAPL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXW4-1", "protein_name": "Microtubule-associated protein 1 light chain 3 gamma", "gene_name": "MAP1LC3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZQ8-1", "protein_name": "Microtubule-associated protein 1 light chain 3 beta", "gene_name": "MAP1LC3B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H0R8", "url": 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"referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Rab GTPase-activating proteins in autophagy: regulation of endocytic and autophagy pathways by direct binding to human ATG8 modifiers.", "journal": "Mol. Cell. Biol.", "date": "2012", "authors": "Popovic D, Akutsu M, Novak I, Harper JW, Behrends C, Dikic I", "reference": { "type": "PubMed", "id": "22354992", "url": "https://pubmed.ncbi.nlm.nih.gov/22354992" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0R8-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 1", "gene_name": "GABARAPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95166-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein", "gene_name": "GABARAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H492-1", "protein_name": "Microtubule-associated protein 1 light chain 3 alpha", "gene_name": "MAP1LC3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60520-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "gene_name": "GABARAPL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXW4-1", "protein_name": "Microtubule-associated protein 1 light chain 3 gamma", "gene_name": "MAP1LC3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZQ8-1", "protein_name": "Microtubule-associated protein 1 light chain 3 beta", "gene_name": "MAP1LC3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92609-1", "protein_name": "TBC1 domain family member 5", "gene_name": "TBC1D5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H0R8", "url": "https://www.uniprot.org/uniprotkb/Q9H0R8" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 59, "end_pos": 59, "sequence_org": "W", "sequence_mut": "A", "comment": "Disrupts interaction with VPS29.", "evidence": [ { "database": "UniProtKB", "id": "Q92609", "url": "https://www.uniprot.org/uniprotkb/Q92609" }, { "database": "PubMed", "id": "22354992", "url": "https://pubmed.ncbi.nlm.nih.gov/22354992" } ], "uniprot_canonical_ac": "Q92609-1" } ], 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "DOR/Tp53inp2 and Tp53inp1 constitute a metazoan gene family encoding dual regulators of autophagy and transcription.", "journal": "PLoS ONE", "date": "2012", "authors": "Sancho Ana, Duran Jordi, Garc\u00eda-Espa\u00f1a Antonio, Mauvezin Caroline, Alemu Endalkachew A, Lamark Trond, Macias Maria J, DeSalle Rob, Royo Miriam, Sala David, Chicote Javier U, Palac\u00edn Manuel, Johansen Terje, Zorzano Antonio", "reference": { "type": "PubMed", "id": "22470510", "url": "https://pubmed.ncbi.nlm.nih.gov/22470510" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H0R8-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 1", "gene_name": "GABARAPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95166-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein", "gene_name": "GABARAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H492-1", "protein_name": "Microtubule-associated protein 1 light chain 3 alpha", "gene_name": "MAP1LC3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P60520-1", "protein_name": "Gamma-aminobutyric acid receptor-associated protein-like 2", "gene_name": "GABARAPL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BXW4-1", "protein_name": "Microtubule-associated protein 1 light chain 3 gamma", "gene_name": "MAP1LC3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZQ8-1", "protein_name": "Microtubule-associated protein 1 light chain 3 beta", "gene_name": "MAP1LC3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXH6-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2", "gene_name": "TP53INP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A56-1", "protein_name": "Tumor protein p53-inducible nuclear protein 1", "gene_name": "TP53INP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H0R8", "url": "https://www.uniprot.org/uniprotkb/Q9H0R8" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22470510", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MAPK15/ERK8 stimulates autophagy by interacting with LC3 and GABARAP proteins.", "journal": "Autophagy", "date": "2012", "authors": "Colecchia D, Strambi A, Sanzone S, Iavarone C, Rossi M, Dall'Armi C, Piccioni F, Verrotti di Pianella A, Chiariello M", "reference": { "type": "PubMed", "id": "22948227", "url": 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"start_pos": 155, "end_pos": 155, "sequence_org": "D", "sequence_mut": "A", "comment": "Unable to induce the formation of autophagosomal structures. Is able to bind to MAP1LC3B and to colocalize with this protein to autophagosomal structures. Does not induce phosphorylation by methyl methanesulfonate. Loas of phosphorylation. Dominant negative mutant. Not phosphorylated at Thr-175 and Tyr-177.", "evidence": [ { "database": "UniProtKB", "id": "Q8TD08", "url": "https://www.uniprot.org/uniprotkb/Q8TD08" }, { "database": "PubMed", "id": "22948227", "url": "https://pubmed.ncbi.nlm.nih.gov/22948227" }, { "database": "PubMed", "id": "16336213", "url": "https://pubmed.ncbi.nlm.nih.gov/16336213" }, { "database": "PubMed", "id": "19166846", "url": "https://pubmed.ncbi.nlm.nih.gov/19166846" } ], "uniprot_canonical_ac": "Q8TD08-1" }, { "start_pos": 340, "end_pos": 343, "sequence_org": "YQMI", "sequence_mut": "AQMA", "comment": "Impairs interaction with GABARAP and MAP1LC3B. Affects subcellular localization in autophagosome. Does not induce autophagy.", "evidence": [ { "database": "UniProtKB", "id": "Q8TD08", "url": "https://www.uniprot.org/uniprotkb/Q8TD08" }, { "database": "PubMed", "id": "22948227", "url": "https://pubmed.ncbi.nlm.nih.gov/22948227" } ], "uniprot_canonical_ac": "Q8TD08-1" } ], "record_id": "pubmed.22948227", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] } ]