[ { "title": "Human SLP-65 isoforms contribute differently to activation and apoptosis of B lymphocytes.", "journal": "Blood", "date": "2006-12-01", "authors": "Grabbe Annika, Wienands J\u00fcrgen", "reference": { "type": "PubMed", "id": "16912232", "url": "https://pubmed.ncbi.nlm.nih.gov/16912232" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9YGC1-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Chicken" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16912232", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Solution structure and phosphopeptide binding of the SH2 domain from the human Bruton's tyrosine kinase.", "journal": "Journal of biomolecular NMR", "date": "2006-09", "authors": "Huang Kuo-Chun, Cheng Hsi-Tsung, Pai Ming-Tao, Tzeng Shiou-Ru, Cheng Jya-Wei", "reference": { "type": "PubMed", "id": "16969585", "url": "https://pubmed.ncbi.nlm.nih.gov/16969585" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06187-1", "protein_name": "Tyrosine-protein kinase BTK", "gene_name": "BTK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 72, "end_pos": 72, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by SYK", "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" }, { "database": "IntAct", "id": "Q8WV28", "url": "https://www.ebi.ac.uk/intact/interactors/id:Q8WV28*" }, { "database": "iPTMnet", "id": "Q8WV28", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8WV28" }, { "database": "PubMed", "id": "16969585", "url": "https://pubmed.ncbi.nlm.nih.gov/16969585" }, { "database": "PRO", "id": "Q8WV28", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q8WV28" }, { "database": "PubMed", "id": "12456653", "url": "https://pubmed.ncbi.nlm.nih.gov/12456653" } ], "site_lbl": "Tyr72", "uniprot_canonical_ac": "Q8WV28-1" } ], "record_id": "pubmed.16969585", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Redundancy in B cell developmental pathways: c-Cbl inactivation rescues early B cell development through a B cell linker protein-independent pathway.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "2007", "authors": "Song H, Zhang J, Chiang YJ, Siraganian RP, Hodes RJ", "reference": { "type": "PubMed", "id": "17202354", "url": "https://pubmed.ncbi.nlm.nih.gov/17202354" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17202354", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The kinase Syk as an adaptor controlling sustained calcium signalling and B-cell development.", "journal": "EMBO J.", "date": "2008", "authors": "Kulathu Y, Hobeika E, Turchinovich G, Reth M", "reference": { "type": "PubMed", "id": "18369315", "url": "https://pubmed.ncbi.nlm.nih.gov/18369315" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48025-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "Syk", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QUN3-1", "protein_name": "B-cell linker protein", "gene_name": "Blnk", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 630, "end_pos": 630, "sequence_org": "Y", "sequence_mut": "F", "comment": "Loss of interaction with BLNK.", "evidence": [ { "database": "UniProtKB", "id": "P43405", "url": "https://www.uniprot.org/uniprotkb/P43405" }, { "database": "PubMed", "id": "18369315", "url": "https://pubmed.ncbi.nlm.nih.gov/18369315" } ], "uniprot_canonical_ac": "P43405-1" }, { "start_pos": 373, "end_pos": 373, "sequence_org": "R", "sequence_mut": "L", "comment": "Abolishes binding to CD79A and SYK.", "evidence": [ { "database": "UniProtKB", "id": "Q9QUN3", "url": "https://www.uniprot.org/uniprotkb/Q9QUN3" }, { "database": "PubMed", "id": "18369315", "url": "https://pubmed.ncbi.nlm.nih.gov/18369315" }, { "database": "PubMed", "id": "11449366", "url": "https://pubmed.ncbi.nlm.nih.gov/11449366" } ], "uniprot_canonical_ac": "Q9QUN3-1" } ], "phosphorylation": [ { "start_pos": 630, "end_pos": 630, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P43405", "url": "https://www.uniprot.org/uniprotkb/P43405" }, { "database": "PubMed", "id": "21469132", "url": "https://pubmed.ncbi.nlm.nih.gov/21469132" }, { "database": "PubMed", "id": "18369315", "url": "https://pubmed.ncbi.nlm.nih.gov/18369315" }, { "database": "IntAct", "id": "P43405", "url": "https://www.ebi.ac.uk/intact/interactors/id:P43405*" }, { "database": "iPTMnet", "id": "P43405", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P43405" } ], "site_lbl": "Tyr630", "uniprot_canonical_ac": "P43405-1" } ], "record_id": "pubmed.18369315", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "FGFR2-Cbl interaction in lipid rafts triggers attenuation of PI3K/Akt signaling and osteoblast survival.", "journal": "Bone", "date": "2008", "authors": "Dufour C, Guenou H, Kaabeche K, Bouvard D, Sanjay A, Marie PJ", "reference": { "type": "PubMed", "id": "18374639", "url": "https://pubmed.ncbi.nlm.nih.gov/18374639" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21802-1", "protein_name": "Fibroblast growth factor receptor 2", "gene_name": "FGFR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18374639", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 22 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Pre-B cell receptor-mediated cell cycle arrest in Philadelphia chromosome-positive acute lymphoblastic leukemia requires IKAROS function.", "journal": "The Journal of experimental medicine", "date": "2009", "authors": "Trageser D, Iacobucci I, Nahar R, Duy C, von Levetzow G, Klemm L, Park E, Schuh W, Gruber T, Herzog S, Kim YM, Hofmann WK, Li A, Storlazzi CT, Jack HM, Groffen J, Martinelli G, Heisterkamp N, Jumaa H, Muschen M", "reference": { "type": "PubMed", "id": "19620627", "url": "https://pubmed.ncbi.nlm.nih.gov/19620627" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 96, "end_pos": 96, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by SYK", "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" }, { "database": "PRO", "id": "Q8WV28", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q8WV28" }, { "database": "iPTMnet", "id": "Q8WV28", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8WV28" }, { "database": "PubMed", "id": "19620627", "url": "https://pubmed.ncbi.nlm.nih.gov/19620627" }, { "database": "PubMed", "id": "12456653", "url": "https://pubmed.ncbi.nlm.nih.gov/12456653" } ], "site_lbl": "Tyr96", "uniprot_canonical_ac": "Q8WV28-1" } ], "record_id": "pubmed.19620627", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SCIMP, a transmembrane adapter protein involved in major histocompatibility complex class II signaling.", "journal": "Mol. Cell. Biol.", "date": "2011", "authors": "Draber P, Vonkova I, Stepanek O, Hrdinka M, Kucova M, Skopcova T, Otahal P, Angelisova P, Horejsi V, Yeung M, Weiss A, Brdicka T", "reference": { "type": "PubMed", "id": "21930792", "url": "https://pubmed.ncbi.nlm.nih.gov/21930792" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q60631-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "Grb2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UWF3-1", "protein_name": "SLP adapter and CSK-interacting membrane protein", "gene_name": "SCIMP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19397-1", "protein_name": "Leukocyte surface antigen CD53", "gene_name": "CD53", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11049-1", "protein_name": "Leukocyte antigen CD37", "gene_name": "CD37", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41240-1", "protein_name": "Tyrosine-protein kinase CSK", "gene_name": "CSK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3UU41-1", "protein_name": "SLP adapter and CSK-interacting membrane protein", "gene_name": "Scimp", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P60033-1", "protein_name": "CD81 antigen", "gene_name": "CD81", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9QUN3-1", "protein_name": "B-cell linker protein", "gene_name": "Blnk", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P62993-1", "protein_name": "Growth factor receptor-bound protein 2", "gene_name": "GRB2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 107, "end_pos": 107, "sequence_org": "Y", "sequence_mut": "F", "comment": "Inhibits interaction with CSK. Stimulates activation of several downstream signaling pathways.", "evidence": [ { "database": "UniProtKB", "id": "Q6UWF3", "url": "https://www.uniprot.org/uniprotkb/Q6UWF3" }, { "database": "PubMed", "id": "21930792", "url": "https://pubmed.ncbi.nlm.nih.gov/21930792" } ], "uniprot_canonical_ac": "Q6UWF3-1" }, { "start_pos": 131, "end_pos": 131, "sequence_org": "Y", "sequence_mut": "F", "comment": "Inhibits interaction with BLNK. Inhibits activation of several downstream signaling pathways.", "evidence": [ { "database": "UniProtKB", "id": "Q6UWF3", "url": "https://www.uniprot.org/uniprotkb/Q6UWF3" }, { "database": "PubMed", "id": "21930792", "url": "https://pubmed.ncbi.nlm.nih.gov/21930792" } ], "uniprot_canonical_ac": "Q6UWF3-1" }, { "start_pos": 69, "end_pos": 69, "sequence_org": "Y", "sequence_mut": "F", "comment": "Inhibits interaction with GRB2.", "evidence": [ { "database": "UniProtKB", "id": "Q6UWF3", "url": "https://www.uniprot.org/uniprotkb/Q6UWF3" }, { "database": "PubMed", "id": "21930792", "url": "https://pubmed.ncbi.nlm.nih.gov/21930792" } ], "uniprot_canonical_ac": "Q6UWF3-1" }, { "start_pos": 81, "end_pos": 86, "sequence_org": "PPLPPR", "sequence_mut": "", "comment": "Inhibits interaction with LYN.", "evidence": [ { "database": "UniProtKB", "id": "Q6UWF3", "url": "https://www.uniprot.org/uniprotkb/Q6UWF3" }, { "database": "PubMed", "id": "21930792", "url": "https://pubmed.ncbi.nlm.nih.gov/21930792" } ], "uniprot_canonical_ac": "Q6UWF3-1" } ], "phosphorylation": [ { "start_pos": 107, "end_pos": 107, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q6UWF3", "url": "https://www.uniprot.org/uniprotkb/Q6UWF3" }, { "database": "PubMed", "id": "21930792", "url": "https://pubmed.ncbi.nlm.nih.gov/21930792" }, { "database": "iPTMnet", "id": "Q6UWF3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6UWF3" } ], "site_lbl": "Tyr107", "uniprot_canonical_ac": "Q6UWF3-1" }, { "start_pos": 131, "end_pos": 131, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q6UWF3", "url": "https://www.uniprot.org/uniprotkb/Q6UWF3" }, { "database": "PubMed", "id": "21930792", "url": "https://pubmed.ncbi.nlm.nih.gov/21930792" }, { "database": "iPTMnet", "id": "Q6UWF3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6UWF3" } ], "site_lbl": "Tyr131", "uniprot_canonical_ac": "Q6UWF3-1" }, { "start_pos": 69, "end_pos": 69, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "Q6UWF3", "url": "https://www.uniprot.org/uniprotkb/Q6UWF3" }, { "database": "PubMed", "id": "21930792", "url": "https://pubmed.ncbi.nlm.nih.gov/21930792" }, { "database": "iPTMnet", "id": "Q6UWF3", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q6UWF3" } ], "site_lbl": "Tyr69", "uniprot_canonical_ac": "Q6UWF3-1" } ], "record_id": "pubmed.21930792", "abstract": "", "glycosylation": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 11 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Down-regulation of B cell receptor signaling by hematopoietic progenitor kinase 1 (HPK1)-mediated phosphorylation and ubiquitination of activated B cell linker protein (BLNK).", "journal": "The Journal of biological chemistry", "date": "2012", "authors": "Wang X, Li JP, Kuo HK, Chiu LL, Dement GA, Lan JL, Chen DY, Yang CY, Hu H, Tan TH", "reference": { "type": "PubMed", "id": "22334673", "url": "https://pubmed.ncbi.nlm.nih.gov/22334673" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 152, "end_pos": 152, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q8WV28", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8WV28" }, { "database": "PubMed", "id": "22334673", "url": "https://pubmed.ncbi.nlm.nih.gov/22334673" } ], "site_lbl": "Thr152", "uniprot_canonical_ac": "Q8WV28-1" } ], "record_id": "pubmed.22334673", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Protein kinase B (AKT) regulates SYK activity and shuttling through 14-3-3 and importin 7.", "journal": "The international journal of biochemistry & cell biology", "date": "2016", "authors": "Mohammad DK, Nore BF, Gustafsson MO, Mohamed AJ, Smith CIE", "reference": { "type": "PubMed", "id": "27381982", "url": "https://pubmed.ncbi.nlm.nih.gov/27381982" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 84, "end_pos": 84, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by SYK", "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" }, { "database": "PRO", "id": "Q8WV28", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=Q8WV28" }, { "database": "iPTMnet", "id": "Q8WV28", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q8WV28" }, { "database": "PubMed", "id": "27381982", "url": "https://pubmed.ncbi.nlm.nih.gov/27381982" }, { "database": "PubMed", "id": "12456653", "url": "https://pubmed.ncbi.nlm.nih.gov/12456653" } ], "site_lbl": "Tyr84", "uniprot_canonical_ac": "Q8WV28-1" } ], "record_id": "pubmed.27381982", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Further delineation of primary B cell immunodeficiency caused by novel variants of the BLNK gene in two Chinese patients.", "journal": "Clinical immunology (Orlando, Fla.)", "date": "2020", "authors": "Li N, Wu J, Wu Y, Xu Y, Yao R, Li G, Zhang J, Zhou Y, Yin L, Yin Y, Yu T, Wang J", "reference": { "type": "PubMed", "id": "32194234", "url": "https://pubmed.ncbi.nlm.nih.gov/32194234" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.32194234", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Involvement of Blnk and Foxo1 in tumor suppression in BCRABL1transformed proB cells.", "journal": "Oncology reports", "date": "2021", "authors": "Zhang P, Wang Y, Qin M, Li D, Odhiambo WO, Yuan M, Lv Z, Liu C, Ma Y, Dong Y, Ji Y", "reference": { "type": "PubMed", "id": "33416167", "url": "https://pubmed.ncbi.nlm.nih.gov/33416167" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9QUN3-1", "protein_name": "B-cell linker protein", "gene_name": "Blnk", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33416167", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Silencing BLNK protects against interleukin-1beta-induced chondrocyte injury through the NF-kappaB signaling pathway.", "journal": "Cytokine", "date": "2021", "authors": "Cheng Y, Li F, Zhang WS, Zou GY, Shen YX", "reference": { "type": "PubMed", "id": "34521030", "url": "https://pubmed.ncbi.nlm.nih.gov/34521030" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4KM52-1", "protein_name": "B-cell linker protein", "gene_name": "Blnk", "tax_name": "Rat" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34521030", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "C/EBPbeta induces B-cell acute lymphoblastic leukemia and cooperates with BLNK mutations.", "journal": "Cancer science", "date": "2021", "authors": "Kurata M, Onishi I, Takahara T, Yamazaki Y, Ishibashi S, Goitsuka R, Kitamura D, Takita J, Hayashi Y, Largaesapda DA, Kitagawa M, Nakamura T", "reference": { "type": "PubMed", "id": "34653294", "url": "https://pubmed.ncbi.nlm.nih.gov/34653294" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34653294", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ErbB2/Her2-dependent downregulation of a cell death-promoting protein BLNK in breast cancer cells is required for 3D breast tumor growth.", "journal": "Cell death & disease", "date": "2022", "authors": "Liu X, Chipurupalli S, Jiang P, Tavasoli M, Yoo BH, McPhee M, Mazinani S, Francia G, Kerbel RS, Rosen KV", "reference": { "type": "PubMed", "id": "35933456", "url": "https://pubmed.ncbi.nlm.nih.gov/35933456" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.35933456", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The proto-oncogene product c-Cbl becomes tyrosine phosphorylated by stimulation with GM-CSF or Epo and constitutively binds to the SH3 domain of Grb2/Ash in human hematopoietic cells.", "journal": "The Journal of biological chemistry", "date": "1995", "authors": "Odai H, Sasaki K, Iwamatsu A, Hanazono Y, Tanaka T, Mitani K, Yazaki Y, Hirai H", "reference": { "type": "PubMed", "id": "7537740", "url": "https://pubmed.ncbi.nlm.nih.gov/7537740" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7537740", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Stimulation through the T cell receptor induces Cbl association with Crk proteins and the guanine nucleotide exchange protein C3G.", "journal": "The Journal of biological chemistry", "date": "1996", "authors": "Reedquist KA, Fukazawa T, Panchamoorthy G, Langdon WY, Shoelson SE, Druker BJ, Band H", "reference": { "type": "PubMed", "id": "8626543", "url": "https://pubmed.ncbi.nlm.nih.gov/8626543" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 774, "end_pos": 774, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P22681", "url": "https://www.uniprot.org/uniprotkb/P22681" }, { "database": "PubMed", "id": "20622007", "url": "https://pubmed.ncbi.nlm.nih.gov/20622007" }, { "database": "PubMed", "id": "26848865", "url": "https://pubmed.ncbi.nlm.nih.gov/26848865" }, { "database": "PubMed", "id": "11997497", "url": "https://pubmed.ncbi.nlm.nih.gov/11997497" }, { "database": "IntAct", "id": "P22681", "url": "https://www.ebi.ac.uk/intact/interactors/id:P22681*" }, { "database": "iPTMnet", "id": "P22681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681" }, { "database": "PubMed", "id": "15556646", "url": "https://pubmed.ncbi.nlm.nih.gov/15556646" }, { "database": "PubMed", "id": "8524328", "url": "https://pubmed.ncbi.nlm.nih.gov/8524328" }, { "database": "PubMed", "id": "8626543", "url": "https://pubmed.ncbi.nlm.nih.gov/8626543" }, { "database": "PRO", "id": "P22681", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P22681" }, { "database": "PubMed", "id": "14615606", "url": "https://pubmed.ncbi.nlm.nih.gov/14615606" }, { "database": "PubMed", "id": "23352614", "url": "https://pubmed.ncbi.nlm.nih.gov/23352614" }, { "database": "PubMed", "id": "23606532", "url": "https://pubmed.ncbi.nlm.nih.gov/23606532" }, { "database": "PubMed", "id": "24457597", "url": "https://pubmed.ncbi.nlm.nih.gov/24457597" }, { "database": "PubMed", "id": "27050377", "url": "https://pubmed.ncbi.nlm.nih.gov/27050377" }, { "database": "PubMed", "id": "34062268", "url": "https://pubmed.ncbi.nlm.nih.gov/34062268" }, { "database": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" } ], "site_lbl": "Tyr774", "uniprot_canonical_ac": "P22681-1" } ], "record_id": "pubmed.8626543", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The two major sites of cbl tyrosine phosphorylation in abl-transformed cells select the crkL SH2 domain.", "journal": "Oncogene", "date": "1996", "authors": "Andoniou CE, Thien CB, Langdon WY", "reference": { "type": "PubMed", "id": "8649859", "url": "https://pubmed.ncbi.nlm.nih.gov/8649859" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8649859", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation of Cbl following stimulation with interleukin-3 and its association with Grb2, Fyn, and phosphatidylinositol 3-kinase.", "journal": "The Journal of biological chemistry", "date": "1997", "authors": "Anderson SM, Burton EA, Koch BL", "reference": { "type": "PubMed", "id": "8995358", "url": "https://pubmed.ncbi.nlm.nih.gov/8995358" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8995358", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Proto-oncoprotein Vav interacts with c-Cbl in activated thymocytes and peripheral T cells.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "1997", "authors": "Marengere LE, Mirtsos C, Kozieradzki I, Veillette A, Mak TW, Penninger JM", "reference": { "type": "PubMed", "id": "9200440", "url": "https://pubmed.ncbi.nlm.nih.gov/9200440" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 700, "end_pos": 700, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by ABL1", "evidence": [ { "database": "UniProtKB", "id": "P22681", "url": "https://www.uniprot.org/uniprotkb/P22681" }, { "database": "IntAct", "id": "P22681", "url": "https://www.ebi.ac.uk/intact/interactors/id:P22681*" }, { "database": "iPTMnet", "id": "P22681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681" }, { "database": "PubMed", "id": "15556646", "url": "https://pubmed.ncbi.nlm.nih.gov/15556646" }, { "database": "PubMed", "id": "9200440", "url": "https://pubmed.ncbi.nlm.nih.gov/9200440" }, { "database": "PubMed", "id": "8524328", "url": "https://pubmed.ncbi.nlm.nih.gov/8524328" }, { "database": "PRO", "id": "P22681", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P22681" }, { "database": "PubMed", "id": "12881521", "url": "https://pubmed.ncbi.nlm.nih.gov/12881521" }, { "database": "PubMed", "id": "20940296", "url": "https://pubmed.ncbi.nlm.nih.gov/20940296" }, { "database": "PubMed", "id": "22880054", "url": "https://pubmed.ncbi.nlm.nih.gov/22880054" }, { "database": "PubMed", "id": "23352614", "url": "https://pubmed.ncbi.nlm.nih.gov/23352614" }, { "database": "PubMed", "id": "23845085", "url": "https://pubmed.ncbi.nlm.nih.gov/23845085" }, { "database": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" }, { "database": "PubMed", "id": "20622007", "url": "https://pubmed.ncbi.nlm.nih.gov/20622007" }, { "database": "PubMed", "id": "11997497", "url": "https://pubmed.ncbi.nlm.nih.gov/11997497" } ], "site_lbl": "Tyr700", "uniprot_canonical_ac": "P22681-1" } ], "record_id": "pubmed.9200440", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation of cbl after stimulation of Nb2 cells with prolactin and its association with phosphatidylinositol 3-kinase.", "journal": "Molecular endocrinology (Baltimore, Md.)", "date": "1997", "authors": "Hunter S, Koch BL, Anderson SM", "reference": { "type": "PubMed", "id": "9259313", "url": "https://pubmed.ncbi.nlm.nih.gov/9259313" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9259313", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Fyn, Yes, and Syk phosphorylation sites in c-Cbl map to the same tyrosine residues that become phosphorylated in activated T cells.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Feshchenko EA, Langdon WY, Tsygankov AY", "reference": { "type": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 700, "end_pos": 700, "kinase_uniprot_canonical_ac": "P43405-1", "kinase_gene_name": "SYK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681" }, { "database": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" }, { "database": "PubMed", "id": "9535867", "url": "https://pubmed.ncbi.nlm.nih.gov/9535867" } ], "site_lbl": "Tyr700", "uniprot_canonical_ac": "P22681-1" }, { "start_pos": 700, "end_pos": 700, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by ABL1", "evidence": [ { "database": "UniProtKB", "id": "P22681", "url": "https://www.uniprot.org/uniprotkb/P22681" }, { "database": "IntAct", "id": "P22681", "url": "https://www.ebi.ac.uk/intact/interactors/id:P22681*" }, { "database": "iPTMnet", "id": "P22681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681" }, { "database": "PubMed", "id": "15556646", "url": "https://pubmed.ncbi.nlm.nih.gov/15556646" }, { "database": "PubMed", "id": "9200440", "url": "https://pubmed.ncbi.nlm.nih.gov/9200440" }, { "database": "PubMed", "id": "8524328", "url": "https://pubmed.ncbi.nlm.nih.gov/8524328" }, { "database": "PRO", "id": "P22681", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P22681" }, { "database": "PubMed", "id": "12881521", "url": "https://pubmed.ncbi.nlm.nih.gov/12881521" }, { "database": "PubMed", "id": "20940296", "url": "https://pubmed.ncbi.nlm.nih.gov/20940296" }, { "database": "PubMed", "id": "22880054", "url": "https://pubmed.ncbi.nlm.nih.gov/22880054" }, { "database": "PubMed", "id": "23352614", "url": "https://pubmed.ncbi.nlm.nih.gov/23352614" }, { "database": "PubMed", "id": "23845085", "url": "https://pubmed.ncbi.nlm.nih.gov/23845085" }, { "database": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" }, { "database": "PubMed", "id": "20622007", "url": "https://pubmed.ncbi.nlm.nih.gov/20622007" }, { "database": "PubMed", "id": "11997497", "url": "https://pubmed.ncbi.nlm.nih.gov/11997497" } ], "site_lbl": "Tyr700", "uniprot_canonical_ac": "P22681-1" }, { "start_pos": 731, "end_pos": 731, "kinase_uniprot_canonical_ac": "P43405-1", "kinase_gene_name": "SYK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681" }, { "database": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" }, { "database": "PubMed", "id": "9535867", "url": "https://pubmed.ncbi.nlm.nih.gov/9535867" } ], "site_lbl": "Tyr731", "uniprot_canonical_ac": "P22681-1" }, { "start_pos": 731, "end_pos": 731, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine; by SRC", "evidence": [ { "database": "UniProtKB", "id": "P22681", "url": "https://www.uniprot.org/uniprotkb/P22681" }, { "database": "iPTMnet", "id": "P22681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681" }, { "database": "PubMed", "id": "15581361", "url": "https://pubmed.ncbi.nlm.nih.gov/15581361" }, { "database": "IntAct", "id": "P22681", "url": "https://www.ebi.ac.uk/intact/interactors/id:P22681*" }, { "database": "PubMed", "id": "15556646", "url": "https://pubmed.ncbi.nlm.nih.gov/15556646" }, { "database": "PubMed", "id": "9160881", "url": "https://pubmed.ncbi.nlm.nih.gov/9160881" }, { "database": "PubMed", "id": "9890970", "url": "https://pubmed.ncbi.nlm.nih.gov/9890970" }, { "database": "PubMed", "id": "9414268", "url": "https://pubmed.ncbi.nlm.nih.gov/9414268" }, { "database": "PRO", "id": "P22681", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P22681" }, { "database": "PubMed", "id": "14615606", "url": "https://pubmed.ncbi.nlm.nih.gov/14615606" }, { "database": "PubMed", "id": "14739300", "url": "https://pubmed.ncbi.nlm.nih.gov/14739300" }, { "database": "PubMed", "id": "15922744", "url": "https://pubmed.ncbi.nlm.nih.gov/15922744" }, { "database": "PubMed", "id": "23352614", "url": "https://pubmed.ncbi.nlm.nih.gov/23352614" }, { "database": "PubMed", "id": "23874206", "url": "https://pubmed.ncbi.nlm.nih.gov/23874206" }, { "database": "PubMed", "id": "25301722", "url": "https://pubmed.ncbi.nlm.nih.gov/25301722" }, { "database": "PubMed", "id": "27050377", "url": "https://pubmed.ncbi.nlm.nih.gov/27050377" }, { "database": "PubMed", "id": "30181811", "url": "https://pubmed.ncbi.nlm.nih.gov/30181811" }, { "database": "PubMed", "id": "33627783", "url": "https://pubmed.ncbi.nlm.nih.gov/33627783" }, { "database": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" } ], "site_lbl": "Tyr731", "uniprot_canonical_ac": "P22681-1" }, { "start_pos": 774, "end_pos": 774, "kinase_uniprot_canonical_ac": "P43405-1", "kinase_gene_name": "SYK", "residue": "Tyr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P22681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681" }, { "database": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" }, { "database": "PubMed", "id": "9535867", "url": "https://pubmed.ncbi.nlm.nih.gov/9535867" } ], "site_lbl": "Tyr774", "uniprot_canonical_ac": "P22681-1" }, { "start_pos": 774, "end_pos": 774, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Tyr", "comment": "Phosphotyrosine", "evidence": [ { "database": "UniProtKB", "id": "P22681", "url": "https://www.uniprot.org/uniprotkb/P22681" }, { "database": "PubMed", "id": "20622007", "url": "https://pubmed.ncbi.nlm.nih.gov/20622007" }, { "database": "PubMed", "id": "26848865", "url": "https://pubmed.ncbi.nlm.nih.gov/26848865" }, { "database": "PubMed", "id": "11997497", "url": "https://pubmed.ncbi.nlm.nih.gov/11997497" }, { "database": "IntAct", "id": "P22681", "url": "https://www.ebi.ac.uk/intact/interactors/id:P22681*" }, { "database": "iPTMnet", "id": "P22681", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P22681" }, { "database": "PubMed", "id": "15556646", "url": "https://pubmed.ncbi.nlm.nih.gov/15556646" }, { "database": "PubMed", "id": "8524328", "url": "https://pubmed.ncbi.nlm.nih.gov/8524328" }, { "database": "PubMed", "id": "8626543", "url": "https://pubmed.ncbi.nlm.nih.gov/8626543" }, { "database": "PRO", "id": "P22681", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=P22681" }, { "database": "PubMed", "id": "14615606", "url": "https://pubmed.ncbi.nlm.nih.gov/14615606" }, { "database": "PubMed", "id": "23352614", "url": "https://pubmed.ncbi.nlm.nih.gov/23352614" }, { "database": "PubMed", "id": "23606532", "url": "https://pubmed.ncbi.nlm.nih.gov/23606532" }, { "database": "PubMed", "id": "24457597", "url": "https://pubmed.ncbi.nlm.nih.gov/24457597" }, { "database": "PubMed", "id": "27050377", "url": "https://pubmed.ncbi.nlm.nih.gov/27050377" }, { "database": "PubMed", "id": "34062268", "url": "https://pubmed.ncbi.nlm.nih.gov/34062268" }, { "database": "PubMed", "id": "9525940", "url": "https://pubmed.ncbi.nlm.nih.gov/9525940" } ], "site_lbl": "Tyr774", "uniprot_canonical_ac": "P22681-1" } ], "record_id": "pubmed.9525940", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 3 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CBL-GRB2 interaction in myeloid immunoreceptor tyrosine activation motif signaling.", "journal": "Journal of immunology (Baltimore, Md. : 1950)", "date": "1998", "authors": "Park RK, Kyono WT, Liu Y, Durden DL", "reference": { "type": "PubMed", "id": "9590251", "url": "https://pubmed.ncbi.nlm.nih.gov/9590251" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8WV28-1", "protein_name": "B-cell linker protein", "gene_name": "BLNK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08631-1", "protein_name": "Tyrosine-protein kinase HCK", "gene_name": "HCK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43405-1", "protein_name": "Tyrosine-protein kinase SYK", "gene_name": "SYK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42336-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform", "gene_name": "PIK3CA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13905-1", "protein_name": "Rap guanine nucleotide exchange factor 1", "gene_name": "RAPGEF1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46109-1", "protein_name": "Crk-like protein", "gene_name": "CRKL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92569-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit gamma", "gene_name": "PIK3R3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00459-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta", "gene_name": "PIK3R2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07947-1", "protein_name": "Tyrosine-protein kinase Yes", "gene_name": "YES1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42338-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform", "gene_name": "PIK3CB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00329-1", "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform", "gene_name": "PIK3CD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27986-1", "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit alpha", "gene_name": "PIK3R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46108-1", "protein_name": "Adapter molecule crk", "gene_name": "CRK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06241-1", "protein_name": "Tyrosine-protein kinase Fyn", "gene_name": "FYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P22681-1", "protein_name": "E3 ubiquitin-protein ligase CBL", "gene_name": "CBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15498-1", "protein_name": "Proto-oncogene vav", "gene_name": "VAV1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8WV28", "url": "https://www.uniprot.org/uniprotkb/Q8WV28" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9590251", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CHMP1 functions as a member of a newly defined family of vesicle trafficking proteins.", "journal": "J. Cell Sci.", "date": "2001", "authors": "Howard TL, Stauffer DR, Degnin CR, Hollenberg SM", "reference": { "type": "PubMed", "id": "11559748", "url": "https://pubmed.ncbi.nlm.nih.gov/11559748" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P69771-1", "protein_name": "Vacuolar protein-sorting-associated protein 46", "gene_name": "DID2", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04272-1", "protein_name": "Vacuolar protein sorting-associated protein 20", "gene_name": "VPS20", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36095-1", "protein_name": "Vacuolar protein-sorting-associated protein 24", "gene_name": "VPS24", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36108-1", "protein_name": "DOA4-independent degradation protein 4", "gene_name": "DID4", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P39929-1", "protein_name": "Vacuolar-sorting protein SNF7", "gene_name": "SNF7", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03390-1", "protein_name": "Vacuolar protein-sorting-associated protein 60", "gene_name": "VPS60", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9HD42-1", "protein_name": "Charged multivesicular body protein 1a", "gene_name": "CHMP1A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 228, "end_pos": 228, "sequence_org": "E", "sequence_mut": "Q", "comment": "Defective in ATP-hydrolysis. Causes membrane association. Induces vacuolation of endosomal compartments and impairs cholesterol and protein sorting. Inhibits HIV-1 release. Increases binding to CHMP1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "15075231", "url": "https://pubmed.ncbi.nlm.nih.gov/15075231" }, { "database": "PubMed", "id": "10637304", "url": "https://pubmed.ncbi.nlm.nih.gov/10637304" }, { "database": "PubMed", "id": "11563910", "url": "https://pubmed.ncbi.nlm.nih.gov/11563910" }, { "database": "PubMed", "id": "11559748", "url": "https://pubmed.ncbi.nlm.nih.gov/11559748" }, { "database": "PubMed", "id": "11595185", "url": "https://pubmed.ncbi.nlm.nih.gov/11595185" } ], "uniprot_canonical_ac": "Q9UN37-1" } ], "record_id": "pubmed.11559748", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking.", "journal": "Journal of molecular biology", "date": "2001", "authors": "Scheuring S, Rohricht RA, Schoning-Burkhardt B, Beyer A, Muller S, Abts HF, Kohrer K", "reference": { "type": "PubMed", "id": "11563910", "url": "https://pubmed.ncbi.nlm.nih.gov/11563910" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRG1-1", "protein_name": "Vacuolar protein-sorting-associated protein 25", "gene_name": "VPS25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VN1-1", "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "VPS36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 235, "end_pos": 235, "sequence_org": "E", "sequence_mut": "Q", "comment": "Defective in vacuolar protein sorting.", "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" }, { "database": "PubMed", "id": "11563910", "url": "https://pubmed.ncbi.nlm.nih.gov/11563910" } ], "uniprot_canonical_ac": "O75351-1" }, { "start_pos": 228, "end_pos": 228, "sequence_org": "E", "sequence_mut": "Q", "comment": "Defective in ATP-hydrolysis. Causes membrane association. Induces vacuolation of endosomal compartments and impairs cholesterol and protein sorting. Inhibits HIV-1 release. Increases binding to CHMP1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "15075231", "url": "https://pubmed.ncbi.nlm.nih.gov/15075231" }, { "database": "PubMed", "id": "10637304", "url": "https://pubmed.ncbi.nlm.nih.gov/10637304" }, { "database": "PubMed", "id": "11563910", "url": "https://pubmed.ncbi.nlm.nih.gov/11563910" }, { "database": "PubMed", "id": "11559748", "url": "https://pubmed.ncbi.nlm.nih.gov/11559748" }, { "database": "PubMed", "id": "11595185", "url": "https://pubmed.ncbi.nlm.nih.gov/11595185" } ], "uniprot_canonical_ac": "Q9UN37-1" } ], "record_id": "pubmed.11563910", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 31 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Comparative sequence and expression analyses of four mammalian VPS4 genes.", "journal": "Gene", "date": "2003", "authors": "Beyer A, Scheuring S, Muller S, Mincheva A, Lichter P, Kohrer K", "reference": { "type": "PubMed", "id": "12594041", "url": "https://pubmed.ncbi.nlm.nih.gov/12594041" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46467-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "Vps4b", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VEJ9-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "Vps4a", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 235, "end_pos": 235, "sequence_org": "E", "sequence_mut": "Q", "comment": "Defective in ATP-hydrolysis. Causes membrane-association. Induces vacuolation of endosomal compartments and impairs cholesterol and protein sorting. Increased perinuclear localization.", "evidence": [ { "database": "UniProtKB", "id": "P46467", "url": "https://www.uniprot.org/uniprotkb/P46467" }, { "database": "PubMed", "id": "10637304", "url": "https://pubmed.ncbi.nlm.nih.gov/10637304" }, { "database": "PubMed", "id": "10679028", "url": "https://pubmed.ncbi.nlm.nih.gov/10679028" }, { "database": "PubMed", "id": "18796009", "url": "https://pubmed.ncbi.nlm.nih.gov/18796009" }, { "database": "PubMed", "id": "12594041", "url": "https://pubmed.ncbi.nlm.nih.gov/12594041" } ], "uniprot_canonical_ac": "P46467-1" }, { "start_pos": 228, "end_pos": 228, "sequence_org": "E", "sequence_mut": "Q", "comment": "Perinuclear localization.", "evidence": [ { "database": "UniProtKB", "id": "Q8VEJ9", "url": "https://www.uniprot.org/uniprotkb/Q8VEJ9" }, { "database": "PubMed", "id": "12594041", "url": "https://pubmed.ncbi.nlm.nih.gov/12594041" } ], "uniprot_canonical_ac": "Q8VEJ9-1" } ], "record_id": "pubmed.12594041", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The protein network of HIV budding.", "journal": "Cell", "date": "2003", "authors": "von Schwedler UK, Stuchell M, Muller B, Ward DM, Chung HY, Morita E, Wang HE, Davis T, He GP, Cimbora DM, Scott A, Krausslich HG, Kaplan J, Morham SG, Sundquist WI", "reference": { "type": "PubMed", "id": "14505570", "url": "https://pubmed.ncbi.nlm.nih.gov/14505570" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7LBR1-1", "protein_name": "Charged multivesicular body protein 1b", "gene_name": "CHMP1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRG1-1", "protein_name": "Vacuolar protein-sorting-associated protein 25", "gene_name": "VPS25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HD42-1", "protein_name": "Charged multivesicular body protein 1a", "gene_name": "CHMP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VN1-1", "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "VPS36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 95, "end_pos": 95, "sequence_org": "M", "sequence_mut": "A", "comment": "Reduces interaction with VPS37B and HIV-1 p6; abolishes interaction with PDCD6IP; impairs HIV-1 budding; inhibits down-regulation of EGFR. Abolishes MGRN1-binding. Loss of interaction with ARRDC1.", "evidence": [ { "database": "UniProtKB", "id": "Q99816", "url": "https://www.uniprot.org/uniprotkb/Q99816" }, { "database": "PubMed", "id": "22315426", "url": "https://pubmed.ncbi.nlm.nih.gov/22315426" }, { "database": "PubMed", "id": "12006492", "url": "https://pubmed.ncbi.nlm.nih.gov/12006492" }, { "database": "PubMed", "id": "12802020", "url": "https://pubmed.ncbi.nlm.nih.gov/12802020" }, { "database": "PubMed", "id": "15218037", "url": "https://pubmed.ncbi.nlm.nih.gov/15218037" }, { "database": "PubMed", "id": "14505570", "url": "https://pubmed.ncbi.nlm.nih.gov/14505570" }, { "database": "PubMed", "id": "17229889", "url": "https://pubmed.ncbi.nlm.nih.gov/17229889" } ], "uniprot_canonical_ac": "Q99816-1" } ], "record_id": "pubmed.14505570", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 16 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hrs function: viruses provide the clue.", "journal": "Trends in cell biology", "date": "2003", "authors": "Clague MJ, Urbe S", "reference": { "type": "PubMed", "id": "14624836", "url": "https://pubmed.ncbi.nlm.nih.gov/14624836" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRG1-1", "protein_name": "Vacuolar protein-sorting-associated protein 25", "gene_name": "VPS25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VN1-1", "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "VPS36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.14624836", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 31 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ATPase-deficient hVPS4 impairs formation of internal endosomal vesicles and stabilizes bilayered clathrin coats on endosomal vacuoles.", "journal": "Journal of cell science", "date": "2004", "authors": "Sachse M, Strous GJ, Klumperman J", "reference": { "type": "PubMed", "id": "15075231", "url": "https://pubmed.ncbi.nlm.nih.gov/15075231" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRG1-1", "protein_name": "Vacuolar protein-sorting-associated protein 25", "gene_name": "VPS25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VN1-1", "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "VPS36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 228, "end_pos": 228, "sequence_org": "E", "sequence_mut": "Q", "comment": "Defective in ATP-hydrolysis. Causes membrane association. Induces vacuolation of endosomal compartments and impairs cholesterol and protein sorting. Inhibits HIV-1 release. Increases binding to CHMP1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "15075231", "url": "https://pubmed.ncbi.nlm.nih.gov/15075231" }, { "database": "PubMed", "id": "10637304", "url": "https://pubmed.ncbi.nlm.nih.gov/10637304" }, { "database": "PubMed", "id": "11563910", "url": "https://pubmed.ncbi.nlm.nih.gov/11563910" }, { "database": "PubMed", "id": "11559748", "url": "https://pubmed.ncbi.nlm.nih.gov/11559748" }, { "database": "PubMed", "id": "11595185", "url": "https://pubmed.ncbi.nlm.nih.gov/11595185" } ], "uniprot_canonical_ac": "Q9UN37-1" } ], "record_id": "pubmed.15075231", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 31 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The human endosomal sorting complex required for transport (ESCRT-I) and its role in HIV-1 budding.", "journal": "The Journal of biological chemistry", "date": "2004", "authors": "Stuchell MD, Garrus JE, Muller B, Stray KM, Ghaffarian S, McKinnon R, Krausslich HG, Morham SG, Sundquist WI", "reference": { "type": "PubMed", "id": "15218037", "url": "https://pubmed.ncbi.nlm.nih.gov/15218037" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60551-1", "protein_name": "Glycylpeptide N-tetradecanoyltransferase 2", "gene_name": "NMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRG1-1", "protein_name": "Vacuolar protein-sorting-associated protein 25", "gene_name": "VPS25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VN1-1", "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "VPS36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 95, "end_pos": 95, "sequence_org": "M", "sequence_mut": "A", "comment": "Reduces interaction with VPS37B and HIV-1 p6; abolishes interaction with PDCD6IP; impairs HIV-1 budding; inhibits down-regulation of EGFR. Abolishes MGRN1-binding. Loss of interaction with ARRDC1.", "evidence": [ { "database": "UniProtKB", "id": "Q99816", "url": "https://www.uniprot.org/uniprotkb/Q99816" }, { "database": "PubMed", "id": "22315426", "url": "https://pubmed.ncbi.nlm.nih.gov/22315426" }, { "database": "PubMed", "id": "12006492", "url": "https://pubmed.ncbi.nlm.nih.gov/12006492" }, { "database": "PubMed", "id": "12802020", "url": "https://pubmed.ncbi.nlm.nih.gov/12802020" }, { "database": "PubMed", "id": "15218037", "url": "https://pubmed.ncbi.nlm.nih.gov/15218037" }, { "database": "PubMed", "id": "14505570", "url": "https://pubmed.ncbi.nlm.nih.gov/14505570" }, { "database": "PubMed", "id": "17229889", "url": "https://pubmed.ncbi.nlm.nih.gov/17229889" } ], "uniprot_canonical_ac": "Q99816-1" } ], "record_id": "pubmed.15218037", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 32 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Retrovirus budding.", "journal": "Annual review of cell and developmental biology", "date": "2004", "authors": "Morita E, Sundquist WI", "reference": { "type": "PubMed", "id": "15473846", "url": "https://pubmed.ncbi.nlm.nih.gov/15473846" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU5-1", "protein_name": "E3 ubiquitin-protein ligase NEDD4-like", "gene_name": "NEDD4L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15473846", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 28 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural characterization of the MIT domain from human Vps4b.", "journal": "Biochemical and biophysical research communications", "date": "2005", "authors": "Takasu H, Jee JG, Ohno A, Goda N, Fujiwara K, Tochio H, Shirakawa M, Hiroaki H", "reference": { "type": "PubMed", "id": "16018968", "url": "https://pubmed.ncbi.nlm.nih.gov/16018968" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16018968", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural and mechanistic studies of VPS4 proteins.", "journal": "The EMBO journal", "date": "2005", "authors": "Scott A, Chung HY, Gonciarz-Swiatek M, Hill GC, Whitby FG, Gaspar J, Holton JM, Viswanathan R, Ghaffarian S, Hill CP, Sundquist WI", "reference": { "type": "PubMed", "id": "16193069", "url": "https://pubmed.ncbi.nlm.nih.gov/16193069" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 208, "end_pos": 209, "sequence_org": "WL", "sequence_mut": "AA", "comment": "Strongly impairs HIV-1 release.", "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" }, { "database": "PubMed", "id": "16193069", "url": "https://pubmed.ncbi.nlm.nih.gov/16193069" } ], "uniprot_canonical_ac": "O75351-1" }, { "start_pos": 210, "end_pos": 210, "sequence_org": "G", "sequence_mut": "A", "comment": "Impairs HIV-1 release.", "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" }, { "database": "PubMed", "id": "16193069", "url": "https://pubmed.ncbi.nlm.nih.gov/16193069" } ], "uniprot_canonical_ac": "O75351-1" }, { "start_pos": 201, "end_pos": 202, "sequence_org": "WL", "sequence_mut": "AA", "comment": "Strongly impairs HIV-1 release.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16193069", "url": "https://pubmed.ncbi.nlm.nih.gov/16193069" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 203, "end_pos": 203, "sequence_org": "G", "sequence_mut": "A", "comment": "Impairs HIV-1 release.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16193069", "url": "https://pubmed.ncbi.nlm.nih.gov/16193069" } ], "uniprot_canonical_ac": "Q9UN37-1" } ], "record_id": "pubmed.16193069", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Degradation of endocytosed epidermal growth factor and virally ubiquitinated major histocompatibility complex class I is independent of mammalian ESCRTII.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Bowers K, Piper SC, Edeling MA, Gray SR, Owen DJ, Lehner PJ, Luzio JP", "reference": { "type": "PubMed", "id": "16371348", "url": "https://pubmed.ncbi.nlm.nih.gov/16371348" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRG1-1", "protein_name": "Vacuolar protein-sorting-associated protein 25", "gene_name": "VPS25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VN1-1", "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "VPS36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16371348", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 31 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release.", "journal": "Journal of virology", "date": "2006", "authors": "Langelier C, von Schwedler UK, Fisher RD, De Domenico I, White PL, Hill CP, Kaplan J, Ward D, Sundquist WI", "reference": { "type": "PubMed", "id": "16973552", "url": "https://pubmed.ncbi.nlm.nih.gov/16973552" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRG1-1", "protein_name": "Vacuolar protein-sorting-associated protein 25", "gene_name": "VPS25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VN1-1", "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "VPS36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16973552", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 31 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "ESCRT-III recognition by VPS4 ATPases.", "journal": "Nature", "date": "2007", "authors": "Stuchell-Brereton MD, Skalicky JJ, Kieffer C, Karren MA, Ghaffarian S, Sundquist WI", "reference": { "type": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52917-1", "protein_name": "Vacuolar protein sorting-associated protein 4", "gene_name": "VPS4", "tax_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7LBR1-1", "protein_name": "Charged multivesicular body protein 1b", "gene_name": "CHMP1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HD42-1", "protein_name": "Charged multivesicular body protein 1a", "gene_name": "CHMP1A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 173, "end_pos": 173, "sequence_org": "K", "sequence_mut": "Q", "comment": "Defective in ATP-binding. Causes membrane association. Induces vacuolation of endosomal compartments and impairs cholesterol sorting. Inhibits HIV-1 release. Greatly diminishes localization to punctate class E compartments and partially restores HIV-1 release; when associated with D-64. Greatly diminishes localization to punctate class E compartments; when associated with D-173.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "10637304", "url": "https://pubmed.ncbi.nlm.nih.gov/10637304" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "11595185", "url": "https://pubmed.ncbi.nlm.nih.gov/11595185" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with CHMP1B; diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Abolishes interaction with CHMP1B; diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Greatly diminishes localization to punctate class E compartments and partially restores HIV-1 release; when associated with Q-173.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Modestly reduces interaction with CHMP6.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Inhibits membrane protein sorting to the vacuole.", "evidence": [ { "database": "UniProtKB", "id": "P52917", "url": "https://www.uniprot.org/uniprotkb/P52917" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" } ], "uniprot_canonical_ac": "P52917-1" }, { "start_pos": 192, "end_pos": 192, "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with SPAST and VPS4A; when associated with A-188.", "evidence": [ { "database": "UniProtKB", "id": "Q7LBR1", "url": "https://www.uniprot.org/uniprotkb/Q7LBR1" }, { "database": "PubMed", "id": "18997780", "url": "https://pubmed.ncbi.nlm.nih.gov/18997780" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" } ], "uniprot_canonical_ac": "Q7LBR1-1" }, { "start_pos": 192, "end_pos": 192, "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with VPS4B.", "evidence": [ { "database": "UniProtKB", "id": "Q7LBR1", "url": "https://www.uniprot.org/uniprotkb/Q7LBR1" }, { "database": "PubMed", "id": "18997780", "url": "https://pubmed.ncbi.nlm.nih.gov/18997780" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" } ], "uniprot_canonical_ac": "Q7LBR1-1" }, { "start_pos": 195, "end_pos": 195, "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with VPS4B.", "evidence": [ { "database": "UniProtKB", "id": "Q7LBR1", "url": "https://www.uniprot.org/uniprotkb/Q7LBR1" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" } ], "uniprot_canonical_ac": "Q7LBR1-1" } ], "record_id": "pubmed.17928862", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Novel interactions of ESCRT-III with LIP5 and VPS4 and their implications for ESCRT-III disassembly.", "journal": "Molecular biology of the cell", "date": "2008", "authors": "Shim S, Merrill SA, Hanson PI", "reference": { "type": "PubMed", "id": "18385515", "url": "https://pubmed.ncbi.nlm.nih.gov/18385515" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7LBR1-1", "protein_name": "Charged multivesicular body protein 1b", "gene_name": "CHMP1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 390, "end_pos": 396, "sequence_org": "GAIEMTW", "sequence_mut": "", "comment": "Abolishes interaction with VTA1.", "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" }, { "database": "PubMed", "id": "18385515", "url": "https://pubmed.ncbi.nlm.nih.gov/18385515" } ], "uniprot_canonical_ac": "O75351-1" }, { "start_pos": 158, "end_pos": 159, "sequence_org": "DE", "sequence_mut": "AA", "comment": "Diminishes interaction with VPS4B.", "evidence": [ { "database": "UniProtKB", "id": "Q7LBR1", "url": "https://www.uniprot.org/uniprotkb/Q7LBR1" }, { "database": "PubMed", "id": "18385515", "url": "https://pubmed.ncbi.nlm.nih.gov/18385515" } ], "uniprot_canonical_ac": "Q7LBR1-1" }, { "start_pos": 169, "end_pos": 170, "sequence_org": "DE", "sequence_mut": "AA", "comment": "Diminishes interaction with VPS4B.", "evidence": [ { "database": "UniProtKB", "id": "O43633", "url": "https://www.uniprot.org/uniprotkb/O43633" }, { "database": "PubMed", "id": "18385515", "url": "https://pubmed.ncbi.nlm.nih.gov/18385515" } ], "uniprot_canonical_ac": "O43633-1" }, { "start_pos": 216, "end_pos": 216, "sequence_org": "L", "sequence_mut": "A", "comment": "Diminishes interaction with VTA1.", "evidence": [ { "database": "UniProtKB", "id": "O43633", "url": "https://www.uniprot.org/uniprotkb/O43633" }, { "database": "PubMed", "id": "18385515", "url": "https://pubmed.ncbi.nlm.nih.gov/18385515" } ], "uniprot_canonical_ac": "O43633-1" }, { "start_pos": 217, "end_pos": 222, "sequence_org": "KNLRRD", "sequence_mut": "", "comment": "Abolishes interaction with VTA1.", "evidence": [ { "database": "UniProtKB", "id": "O43633", "url": "https://www.uniprot.org/uniprotkb/O43633" }, { "database": "PubMed", "id": "18385515", "url": "https://pubmed.ncbi.nlm.nih.gov/18385515" } ], "uniprot_canonical_ac": "O43633-1" } ], "record_id": "pubmed.18385515", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Two distinct modes of ESCRT-III recognition are required for VPS4 functions in lysosomal protein targeting and HIV-1 budding.", "journal": "Developmental cell", "date": "2008", "authors": "Kieffer C, Skalicky JJ, Morita E, De Domenico I, Ward DM, Kaplan J, Sundquist WI", "reference": { "type": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 15, "end_pos": 15, "sequence_org": "A", "sequence_mut": "D", "comment": "Reduces HIV-1 release 10-fold; when associated with D-66.", "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" } ], "uniprot_canonical_ac": "O75351-1" }, { "start_pos": 15, "end_pos": 15, "sequence_org": "A", "sequence_mut": "D", "comment": "Reduces HIV-1 release 2-fold.", "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" } ], "uniprot_canonical_ac": "O75351-1" }, { "start_pos": 66, "end_pos": 66, "sequence_org": "L", "sequence_mut": "D", "comment": "Reduces HIV-1 release 10-fold; when associated with D-15.", "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" } ], "uniprot_canonical_ac": "O75351-1" }, { "start_pos": 66, "end_pos": 66, "sequence_org": "L", "sequence_mut": "D", "comment": "Reduces HIV-1 release 3-fold.", "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" } ], "uniprot_canonical_ac": "O75351-1" }, { "start_pos": 13, "end_pos": 13, "sequence_org": "V", "sequence_mut": "A", "comment": "Diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 13, "end_pos": 13, "sequence_org": "V", "sequence_mut": "D", "comment": "Abolishes interaction with CHMP6, no effect on interaction with CHMP1A.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 13, "end_pos": 13, "sequence_org": "V", "sequence_mut": "D", "comment": "Diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 13, "end_pos": 13, "sequence_org": "V", "sequence_mut": "D", "comment": "Greatly diminishes localization to punctate class E compartments; when associated with Q-173.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 173, "end_pos": 173, "sequence_org": "K", "sequence_mut": "Q", "comment": "Defective in ATP-binding. Causes membrane association. Induces vacuolation of endosomal compartments and impairs cholesterol sorting. Inhibits HIV-1 release. Greatly diminishes localization to punctate class E compartments and partially restores HIV-1 release; when associated with D-64. Greatly diminishes localization to punctate class E compartments; when associated with D-173.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "10637304", "url": "https://pubmed.ncbi.nlm.nih.gov/10637304" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "11595185", "url": "https://pubmed.ncbi.nlm.nih.gov/11595185" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with CHMP1B; diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Abolishes interaction with CHMP1B; diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Greatly diminishes localization to punctate class E compartments and partially restores HIV-1 release; when associated with Q-173.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Modestly reduces interaction with CHMP6.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 170, "end_pos": 170, "sequence_org": "L", "sequence_mut": "D", "comment": "Abolishes interaction with VPS4A.", "evidence": [ { "database": "UniProtKB", "id": "Q96FZ7", "url": "https://www.uniprot.org/uniprotkb/Q96FZ7" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" } ], "uniprot_canonical_ac": "Q96FZ7-1" }, { "start_pos": 173, "end_pos": 173, "sequence_org": "V", "sequence_mut": "D", "comment": "Abolishes interaction with VPS4A.", "evidence": [ { "database": "UniProtKB", "id": "Q96FZ7", "url": "https://www.uniprot.org/uniprotkb/Q96FZ7" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" } ], "uniprot_canonical_ac": "Q96FZ7-1" }, { "start_pos": 178, "end_pos": 178, "sequence_org": "L", "sequence_mut": "D", "comment": "Reduces interaction with VPS4A.", "evidence": [ { "database": "UniProtKB", "id": "Q96FZ7", "url": "https://www.uniprot.org/uniprotkb/Q96FZ7" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" } ], "uniprot_canonical_ac": "Q96FZ7-1" } ], "record_id": "pubmed.18606141", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Helical structures of ESCRT-III are disassembled by VPS4.", "journal": "Science (New York, N.Y.)", "date": "2008", "authors": "Lata S, Schoehn G, Jain A, Pires R, Piehler J, Gottlinger HG, Weissenhorn W", "reference": { "type": "PubMed", "id": "18687924", "url": "https://pubmed.ncbi.nlm.nih.gov/18687924" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18687924", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Biochemical analyses of human IST1 and its function in cytokinesis.", "journal": "Mol. Biol. Cell", "date": "2009", "authors": "Bajorek M, Morita E, Skalicky JJ, Morham SG, Babst M, Sundquist WI", "reference": { "type": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7LBR1-1", "protein_name": "Charged multivesicular body protein 1b", "gene_name": "CHMP1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HD42-1", "protein_name": "Charged multivesicular body protein 1a", "gene_name": "CHMP1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53990-1", "protein_name": "IST1 homolog", "gene_name": "IST1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 13, "end_pos": 13, "sequence_org": "V", "sequence_mut": "A", "comment": "Diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 13, "end_pos": 13, "sequence_org": "V", "sequence_mut": "D", "comment": "Abolishes interaction with CHMP6, no effect on interaction with CHMP1A.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 13, "end_pos": 13, "sequence_org": "V", "sequence_mut": "D", "comment": "Diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 13, "end_pos": 13, "sequence_org": "V", "sequence_mut": "D", "comment": "Greatly diminishes localization to punctate class E compartments; when associated with Q-173.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "A", "comment": "Abolishes interaction with CHMP1B; diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Abolishes interaction with CHMP1B; diminishes interaction with IST1.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Greatly diminishes localization to punctate class E compartments and partially restores HIV-1 release; when associated with Q-173.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 64, "end_pos": 64, "sequence_org": "L", "sequence_mut": "D", "comment": "Modestly reduces interaction with CHMP6.", "evidence": [ { "database": "UniProtKB", "id": "Q9UN37", "url": "https://www.uniprot.org/uniprotkb/Q9UN37" }, { "database": "PubMed", "id": "16174732", "url": "https://pubmed.ncbi.nlm.nih.gov/16174732" }, { "database": "PubMed", "id": "18606141", "url": "https://pubmed.ncbi.nlm.nih.gov/18606141" }, { "database": "PubMed", "id": "17928862", "url": "https://pubmed.ncbi.nlm.nih.gov/17928862" }, { "database": "PubMed", "id": "19129480", "url": "https://pubmed.ncbi.nlm.nih.gov/19129480" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9UN37-1" }, { "start_pos": 191, "end_pos": 191, "sequence_org": "L", "sequence_mut": "A", "comment": "No effect on interaction with IST1; when associated with L-194.", "evidence": [ { "database": "UniProtKB", "id": "Q9HD42", "url": "https://www.uniprot.org/uniprotkb/Q9HD42" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9HD42-1" }, { "start_pos": 194, "end_pos": 194, "sequence_org": "L", "sequence_mut": "A", "comment": "No effect on interaction with IST1; when associated with L-194.", "evidence": [ { "database": "UniProtKB", "id": "Q9HD42", "url": "https://www.uniprot.org/uniprotkb/Q9HD42" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "Q9HD42-1" }, { "start_pos": 323, "end_pos": 323, "sequence_org": "L", "sequence_mut": "D", "comment": "Diminishes interaction with VPS4A. Greatly diminishes interaction with VPS4A; when associated with A-353.", "evidence": [ { "database": "UniProtKB", "id": "P53990", "url": "https://www.uniprot.org/uniprotkb/P53990" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "P53990-1" }, { "start_pos": 326, "end_pos": 326, "sequence_org": "L", "sequence_mut": "D", "comment": "Diminishes interaction with VPS4A. Greatly diminishes interaction with VPS4A and abolishes interaction with VTA1; when associated with A-353. Greatly diminishes interaction with VPS4A; when associated with A-360.", "evidence": [ { "database": "UniProtKB", "id": "P53990", "url": "https://www.uniprot.org/uniprotkb/P53990" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "P53990-1" }, { "start_pos": 353, "end_pos": 353, "sequence_org": "L", "sequence_mut": "A", "comment": "Diminishes interaction with VPS4A. Greatly diminishes interaction with VPS4A and abolishes interaction with VTA1; when associated with D-326. Greatly diminishes interaction with VPS4A; when associated with D-323.", "evidence": [ { "database": "UniProtKB", "id": "P53990", "url": "https://www.uniprot.org/uniprotkb/P53990" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "P53990-1" }, { "start_pos": 360, "end_pos": 360, "sequence_org": "L", "sequence_mut": "A", "comment": "Diminishes interaction with VPS4A. Greatly diminishes interaction with VPS4A; when associated with D-326.", "evidence": [ { "database": "UniProtKB", "id": "P53990", "url": "https://www.uniprot.org/uniprotkb/P53990" }, { "database": "PubMed", "id": "19129479", "url": "https://pubmed.ncbi.nlm.nih.gov/19129479" } ], "uniprot_canonical_ac": "P53990-1" } ], "record_id": "pubmed.19129479", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The cell biology of HIV-1 virion genesis.", "journal": "Cell host & microbe", "date": "2009", "authors": "Bieniasz PD", "reference": { "type": "PubMed", "id": "19527882", "url": "https://pubmed.ncbi.nlm.nih.gov/19527882" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU5-1", "protein_name": "E3 ubiquitin-protein ligase NEDD4-like", "gene_name": "NEDD4L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19527882", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 28 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "UBAP1 is a component of an endosome-specific ESCRT-I complex that is essential for MVB sorting.", "journal": "Current biology : CB", "date": "2011", "authors": "Stefani F, Zhang L, Taylor S, Donovan J, Rollinson S, Doyotte A, Brownhill K, Bennion J, Pickering-Brown S, Woodman P", "reference": { "type": "PubMed", "id": "21757351", "url": "https://pubmed.ncbi.nlm.nih.gov/21757351" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92783-1", "protein_name": "Signal transducing adapter molecule 1", "gene_name": "STAM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRG1-1", "protein_name": "Vacuolar protein-sorting-associated protein 25", "gene_name": "VPS25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H3S7-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 23", "gene_name": "PTPN23", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VN1-1", "protein_name": "Vacuolar protein-sorting-associated protein 36", "gene_name": "VPS36", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14964-1", "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate", "gene_name": "HGS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75886-1", "protein_name": "Signal transducing adapter molecule 2", "gene_name": "STAM2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 678, "end_pos": 678, "sequence_org": "F", "sequence_mut": "D", "comment": "Abolishes interaction with UBAP1.", "evidence": [ { "database": "UniProtKB", "id": "Q9H3S7", "url": "https://www.uniprot.org/uniprotkb/Q9H3S7" }, { "database": "PubMed", "id": "21757351", "url": "https://pubmed.ncbi.nlm.nih.gov/21757351" }, { "database": "PubMed", "id": "27839950", "url": "https://pubmed.ncbi.nlm.nih.gov/27839950" } ], "uniprot_canonical_ac": "Q9H3S7-1" }, { "start_pos": 678, "end_pos": 678, "sequence_org": "F", "sequence_mut": "S", "comment": "Abolishes interaction with UBAP1.", "evidence": [ { "database": "UniProtKB", "id": "Q9H3S7", "url": "https://www.uniprot.org/uniprotkb/Q9H3S7" }, { "database": "PubMed", "id": "21757351", "url": "https://pubmed.ncbi.nlm.nih.gov/21757351" }, { "database": "PubMed", "id": "27839950", "url": "https://pubmed.ncbi.nlm.nih.gov/27839950" } ], "uniprot_canonical_ac": "Q9H3S7-1" }, { "start_pos": 37, "end_pos": 37, "sequence_org": "P", "sequence_mut": "A", "comment": "Abolishes association with the ESCRT-I complex.", "evidence": [ { "database": "UniProtKB", "id": "Q9NZ09", "url": "https://www.uniprot.org/uniprotkb/Q9NZ09" }, { "database": "PubMed", "id": "21757351", "url": "https://pubmed.ncbi.nlm.nih.gov/21757351" } ], "uniprot_canonical_ac": "Q9NZ09-1" }, { "start_pos": 404, "end_pos": 404, "sequence_org": "Y", "sequence_mut": "A", "comment": "Strongly reduced interaction with ubiquitinated proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q9NZ09", "url": "https://www.uniprot.org/uniprotkb/Q9NZ09" }, { "database": "PubMed", "id": "21757351", "url": "https://pubmed.ncbi.nlm.nih.gov/21757351" } ], "uniprot_canonical_ac": "Q9NZ09-1" }, { "start_pos": 472, "end_pos": 472, "sequence_org": "F", "sequence_mut": "A", "comment": "Strongly reduced interaction with ubiquitinated proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q9NZ09", "url": "https://www.uniprot.org/uniprotkb/Q9NZ09" }, { "database": "PubMed", "id": "21757351", "url": "https://pubmed.ncbi.nlm.nih.gov/21757351" } ], "uniprot_canonical_ac": "Q9NZ09-1" }, { "start_pos": 59, "end_pos": 59, "sequence_org": "E", "sequence_mut": "G", "comment": "Abolishes association with the ESCRT-I complex.", "evidence": [ { "database": "UniProtKB", "id": "Q9NZ09", "url": "https://www.uniprot.org/uniprotkb/Q9NZ09" }, { "database": "PubMed", "id": "21757351", "url": "https://pubmed.ncbi.nlm.nih.gov/21757351" } ], "uniprot_canonical_ac": "Q9NZ09-1" } ], "record_id": "pubmed.21757351", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 32 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of an AAA ATPase VPS4B-dependent pathway that modulates epidermal growth factor receptor abundance and signaling during hypoxia.", "journal": "Molecular and cellular biology", "date": "2012", "authors": "Lin HH, Li X, Chen JL, Sun X, Cooper FN, Chen YR, Zhang W, Chung Y, Li A, Cheng CT, Yang L, Deng X, Liu X, Yen Y, Johnson DL, Shih HM, Yang A, Ann DK", "reference": { "type": "PubMed", "id": "22252323", "url": "https://pubmed.ncbi.nlm.nih.gov/22252323" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22252323", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Syndecan-syntenin-ALIX regulates the biogenesis of exosomes.", "journal": "Nature cell biology", "date": "2012", "authors": "Baietti MF, Zhang Z, Mortier E, Melchior A, Degeest G, Geeraerts A, Ivarsson Y, Depoortere F, Coomans C, Vermeiren E, Zimmermann P, David G", "reference": { "type": "PubMed", "id": "22660413", "url": "https://pubmed.ncbi.nlm.nih.gov/22660413" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96H20-1", "protein_name": "Vacuolar-sorting protein SNF8", "gene_name": "SNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18827-1", "protein_name": "Syndecan-1", "gene_name": "SDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08962-1", "protein_name": "CD63 antigen", "gene_name": "CD63", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P31431-1", "protein_name": "Syndecan-4", "gene_name": "SDC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52848-1", "protein_name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1", "gene_name": "NDST1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20339-1", "protein_name": "Ras-related protein Rab-5A", "gene_name": "RAB5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9WU78-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "Pdcd6ip", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O08992-1", "protein_name": "Syntenin-1", "gene_name": "Sdcbp", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P34741-1", "protein_name": "Syndecan-2", "gene_name": "SDC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16394-1", "protein_name": "Exostosin-1", "gene_name": "EXT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51149-1", "protein_name": "Ras-related protein Rab-7a", "gene_name": "RAB7A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52849-1", "protein_name": "Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 2", "gene_name": "NDST2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93063-1", "protein_name": "Exostosin-2", "gene_name": "EXT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00560-1", "protein_name": "Syntenin-1", "gene_name": "SDCBP", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 676, "end_pos": 676, "sequence_org": "F", "sequence_mut": "A", "comment": "Loss of interaction with SDCBP.", "evidence": [ { "database": "UniProtKB", "id": "Q8WUM4", "url": "https://www.uniprot.org/uniprotkb/Q8WUM4" }, { "database": "PubMed", "id": "22660413", "url": "https://pubmed.ncbi.nlm.nih.gov/22660413" } ], "uniprot_canonical_ac": "Q8WUM4-1" }, { "start_pos": 47, "end_pos": 48, "sequence_org": "YP", "sequence_mut": "AA", "comment": "No loss of interaction with PDCD6IP. Loss of interaction with PDCD6IP; when associated with 4-A--A-5 and 51-A--A-52.", "evidence": [ { "database": "UniProtKB", "id": "O08992", "url": "https://www.uniprot.org/uniprotkb/O08992" }, { "database": "PubMed", "id": "22660413", "url": "https://pubmed.ncbi.nlm.nih.gov/22660413" } ], "uniprot_canonical_ac": "O08992-1" }, { "start_pos": 4, "end_pos": 5, "sequence_org": "YP", "sequence_mut": "AA", "comment": "No loss of interaction with PDCD6IP. Loss of interaction with PDCD6IP; when associated with 46-A--A-47 and 50-A--A-51.", "evidence": [ { "database": "UniProtKB", "id": "O08992", "url": "https://www.uniprot.org/uniprotkb/O08992" }, { "database": "PubMed", "id": "22660413", "url": "https://pubmed.ncbi.nlm.nih.gov/22660413" } ], "uniprot_canonical_ac": "O08992-1" }, { "start_pos": 51, "end_pos": 52, "sequence_org": "YP", "sequence_mut": "AA", "comment": "No loss of interaction with PDCD6IP. Loss of interaction with PDCD6IP; when associated with 4-A--A-5 and 47-A--A-48.", "evidence": [ { "database": "UniProtKB", "id": "O08992", "url": "https://www.uniprot.org/uniprotkb/O08992" }, { "database": "PubMed", "id": "22660413", "url": "https://pubmed.ncbi.nlm.nih.gov/22660413" } ], "uniprot_canonical_ac": "O08992-1" } ], "record_id": "pubmed.22660413", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 21 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "HIV-1 assembly, budding, and maturation.", "journal": "Cold Spring Harbor perspectives in medicine", "date": "2012", "authors": "Sundquist WI, Krausslich HG", "reference": { "type": "PubMed", "id": "22762019", "url": "https://pubmed.ncbi.nlm.nih.gov/22762019" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU5-1", "protein_name": "E3 ubiquitin-protein ligase NEDD4-like", "gene_name": "NEDD4L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22762019", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 28 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "HIV Gag polyprotein: processing and early viral particle assembly.", "journal": "Trends in microbiology", "date": "2013", "authors": "Bell NM, Lever AM", "reference": { "type": "PubMed", "id": "23266279", "url": "https://pubmed.ncbi.nlm.nih.gov/23266279" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU5-1", "protein_name": "E3 ubiquitin-protein ligase NEDD4-like", "gene_name": "NEDD4L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23266279", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 28 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Wrapping up the bad news: HIV assembly and release.", "journal": "Retrovirology", "date": "2013", "authors": "Meng B, Lever AM", "reference": { "type": "PubMed", "id": "23305486", "url": "https://pubmed.ncbi.nlm.nih.gov/23305486" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FZ7-1", "protein_name": "Charged multivesicular body protein 6", "gene_name": "CHMP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUX9-1", "protein_name": "Charged multivesicular body protein 7", "gene_name": "CHMP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BY43-1", "protein_name": "Charged multivesicular body protein 4a", "gene_name": "CHMP4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3E7-1", "protein_name": "Charged multivesicular body protein 3", "gene_name": "CHMP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43633-1", "protein_name": "Charged multivesicular body protein 2a", "gene_name": "CHMP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQN3-1", "protein_name": "Charged multivesicular body protein 2b", "gene_name": "CHMP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99816-1", "protein_name": "Tumor susceptibility gene 101 protein", "gene_name": "TSG101", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM4-1", "protein_name": "Programmed cell death 6-interacting protein", "gene_name": "PDCD6IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CF2-1", "protein_name": "Charged multivesicular body protein 4c", "gene_name": "CHMP4C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZZ3-1", "protein_name": "Charged multivesicular body protein 5", "gene_name": "CHMP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7P6-1", "protein_name": "Multivesicular body subunit 12B", "gene_name": "MVB12B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XT2-1", "protein_name": "Vacuolar protein sorting-associated protein 37D", "gene_name": "VPS37D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62937-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A", "gene_name": "PPIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9H4-1", "protein_name": "Vacuolar protein sorting-associated protein 37B", "gene_name": "VPS37B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5D8V6-1", "protein_name": "Vacuolar protein sorting-associated protein 37C", "gene_name": "VPS37C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H444-1", "protein_name": "Charged multivesicular body protein 4b", "gene_name": "CHMP4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZ09-1", "protein_name": "Ubiquitin-associated protein 1", "gene_name": "UBAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NP79-1", "protein_name": "Vacuolar protein sorting-associated protein VTA1 homolog", "gene_name": "VTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU5-1", "protein_name": "E3 ubiquitin-protein ligase NEDD4-like", "gene_name": "NEDD4L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96EY5-1", "protein_name": "Multivesicular body subunit 12A", "gene_name": "MVB12A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UK41-1", "protein_name": "Vacuolar protein sorting-associated protein 28 homolog", "gene_name": "VPS28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ2-1", "protein_name": "Vacuolar protein sorting-associated protein 37A", "gene_name": "VPS37A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23305486", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 28 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A splicing mutation in VPS4B causes dentin dysplasia I.", "journal": "J. Med. Genet.", "date": "2016", "authors": "Yang Q, Chen D, Xiong F, Chen D, Liu C, Liu Y, Yu Q, Xiong J, Liu J, Li K, Zhao L, Ye Y, Zhou H, Hu L, Tian Z, Shang X, Zhang L, Wei X, Zhou W, Li D, Zhang W, Xu X", "reference": { "type": "PubMed", "id": "27247351", "url": "https://pubmed.ncbi.nlm.nih.gov/27247351" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0AC58GK36-1", "protein_name": "vesicle-fusing ATPase", "gene_name": "vps4b", "tax_name": "Zebrafish" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27247351", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Neoepitope targets of tumour-infiltrating lymphocytes from patients with pancreatic cancer.", "journal": "British journal of cancer", "date": "2019-01", "authors": "Meng Qingda, Valentini Davide, Rao Martin, Moro Carlos Fern\u00e1ndez, Paraschoudi Georgia, J\u00e4ger Elke, Dodoo Ernest, Rangelova Elena, Del Chiaro Marco, Maeurer Markus", "reference": { "type": "PubMed", "id": "30377343", "url": "https://pubmed.ncbi.nlm.nih.gov/30377343" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15397-1", "protein_name": "Importin-8", "gene_name": "IPO8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13569-1", "protein_name": "Cystic fibrosis transmembrane conductance regulator", "gene_name": "CFTR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IZD9-1", "protein_name": "Dedicator of cytokinesis protein 3", "gene_name": "DOCK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4G0A6-1", "protein_name": "Probable ubiquitin carboxyl-terminal hydrolase MINDY-4", "gene_name": "MINDY4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86VD1-1", "protein_name": "MORC family CW-type zinc finger protein 1", "gene_name": "MORC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P273-1", "protein_name": "Teneurin-3", "gene_name": "TENM3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.30377343", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I.", "journal": "International journal of oral science", "date": "2020", "authors": "Li Q, Lu F, Chen T, Zhang K, Lu Y, Li X, Wang Y, Liu L, Tian Q, Xiong F, Chen D", "reference": { "type": "PubMed", "id": "32737282", "url": "https://pubmed.ncbi.nlm.nih.gov/32737282" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.32737282", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.", "journal": "Cell reports", "date": "2020", "authors": "Neggers JE, Paolella BR, Asfaw A, Rothberg MV, Skipper TA, Yang A, Kalekar RL, Krill-Burger JM, Dharia NV, Kugener G, Kalfon J, Yuan C, Dumont N, Gonzalez A, Abdusamad M, Li YY, Spurr LF, Wu WW, Durbin AD, Wolpin BM, Piccioni F, Root DE, Boehm JS, Cherniack AD, Tsherniak A, Hong AL, Hahn WC, Stegmaier K, Golub TR, Vazquez F, Aguirre AJ", "reference": { "type": "PubMed", "id": "33326793", "url": "https://pubmed.ncbi.nlm.nih.gov/33326793" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33326793", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Analysis of individual HIV-1 budding event using fast AFM reveals a multiplexed role for VPS4.", "journal": "Biophysical journal", "date": "2022-11-01", "authors": "Harel Shimon, Altaras Yarin, Nachmias Dikla, Rotem-Dai Noa, Dvilansky Inbar, Elia Natalie, Rousso Itay", "reference": { "type": "PubMed", "id": "36042696", "url": "https://pubmed.ncbi.nlm.nih.gov/36042696" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN37-1", "protein_name": "Vacuolar protein sorting-associated protein 4A", "gene_name": "VPS4A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36042696", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "p-AKT/VPS4B regulates the small extracellular vesicle size in venous malformation endothelial cells.", "journal": "Oral diseases", "date": "2024-04", "authors": "Lai Wen-Qiang, Xia Hou-Fu, Chen Gao-Hong, Wang Xiao-Le, Yang Jie-Gang, Wu Lian-Zhi, Zhao Yi-Fang, Jia Yu-Lin, Chen Gang", "reference": { "type": "PubMed", "id": "37154262", "url": "https://pubmed.ncbi.nlm.nih.gov/37154262" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.37154262", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Improved VPS4B O-GlcNAc modification triggers lipid droplets transferring from adipocytes to nasopharyngeal carcinoma cells.", "journal": "Cancer & metabolism", "date": "2025-05-23", "authors": "Yin Haimeng, Shan Ying, Zhu Qin, Yuan Ling, Ju Feng, Shi Yu, Han Yumo, Wu Rui, Xia Tian, Zhang Kaiwen, You Yiwen, You Bo", "reference": { "type": "PubMed", "id": "40410860", "url": "https://pubmed.ncbi.nlm.nih.gov/40410860" }, "referenced_glycans": [ { "glytoucan_ac": "G49108TO" } ], "referenced_proteins": [ { "uniprot_canonical_ac": "O75351-1", "protein_name": "Vacuolar protein sorting-associated protein 4B", "gene_name": "VPS4B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O75351", "url": "https://www.uniprot.org/uniprotkb/O75351" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "28510447", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/28510447" }, { "id": "O75351", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=O75351" }, { "id": "40914422", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/40914422" }, { "id": "40410860", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/40410860" } ], "filter_code": "000000000000000000000.xxxxxxx.00000001000000.xxxxxxx.xxxxxxxxxx.xxxxxxxxxxxxxxxxxx.xxxxx.01000", "uniprot_canonical_ac": "O75351-1" } ], "record_id": "pubmed.40410860", "abstract": "", "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "glytoucan_ac" ] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sorting nexin 4 and amphiphysin 2, a new partnership between endocytosis and intracellular trafficking.", "journal": "Journal of cell science", "date": "2003", "authors": "Leprince C, Le Scolan E, Meunier B, Fraisier V, Brandon N, De Gunzburg J, Camonis J", "reference": { "type": "PubMed", "id": "12668730", "url": "https://pubmed.ncbi.nlm.nih.gov/12668730" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O95219-1", "protein_name": "Sorting nexin-4", "gene_name": "SNX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O08539-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "Bin1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "O00499-1", "protein_name": "Myc box-dependent-interacting protein 1", "gene_name": "BIN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q91YJ2-1", "protein_name": "Sorting nexin-4", "gene_name": "Snx4", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O95219", "url": "https://www.uniprot.org/uniprotkb/O95219" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12668730", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartment.", "journal": "Nature cell biology", "date": "2007", "authors": "Traer CJ, Rutherford AC, Palmer KJ, Wassmer T, Oakley J, Attar N, Carlton JG, Kremerskothen J, Stephens DJ, Cullen PJ", "reference": { "type": "PubMed", "id": "17994011", "url": "https://pubmed.ncbi.nlm.nih.gov/17994011" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O95219-1", "protein_name": "Sorting nexin-4", "gene_name": "SNX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IX03-1", "protein_name": "Protein KIBRA", "gene_name": "WWC1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O95219", "url": "https://www.uniprot.org/uniprotkb/O95219" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 132, "end_pos": 132, "sequence_org": "K", "sequence_mut": "A", "comment": "Abolishes phosphatidylinositol phosphate binding. Abolishes endosomal location.", "evidence": [ { "database": "UniProtKB", "id": "O95219", "url": "https://www.uniprot.org/uniprotkb/O95219" }, { "database": "PubMed", "id": "17994011", "url": "https://pubmed.ncbi.nlm.nih.gov/17994011" } ], "uniprot_canonical_ac": "O95219-1" } ], "record_id": "pubmed.17994011", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A heterodimeric SNX4--SNX7 SNX-BAR autophagy complex coordinates ATG9A trafficking for efficient autophagosome assembly.", "journal": "Journal of cell science", "date": "2020-07-15", "authors": "Ant\u00f3n Zuri\u00f1e, Betin Virginie M S, Simonetti Boris, Traer Colin J, Attar Naomi, Cullen Peter J, Lane Jon D", "reference": { "type": "PubMed", "id": "32513819", "url": "https://pubmed.ncbi.nlm.nih.gov/32513819" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O95219-1", "protein_name": "Sorting nexin-4", "gene_name": "SNX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNH6-1", "protein_name": "Sorting nexin-7", "gene_name": "SNX7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5VWJ9-1", "protein_name": "Sorting nexin-30", "gene_name": "SNX30", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3C6-1", "protein_name": "Autophagy-related protein 9A", "gene_name": "ATG9A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O95219", "url": "https://www.uniprot.org/uniprotkb/O95219" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.32513819", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The phosphatidylinositol 3-phosphate-binding protein SNX4 controls ATG9A recycling and autophagy.", "journal": "Journal of cell science", "date": "2021", "authors": "Ravussin A, Brech A, Tooze SA, Stenmark H", "reference": { "type": "PubMed", "id": "33468622", "url": "https://pubmed.ncbi.nlm.nih.gov/33468622" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O95219-1", "protein_name": "Sorting nexin-4", "gene_name": "SNX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3C6-1", "protein_name": "Autophagy-related protein 9A", "gene_name": "ATG9A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O95219", "url": "https://www.uniprot.org/uniprotkb/O95219" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33468622", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Comprehensive mutagenesis identifies the peptide repertoire of a p53 T-cell receptor mimic antibody that displays no toxicity in mice transgenic for human HLA-A*0201.", "journal": "PloS one", "date": "2021", "authors": "Trenevska Iva, Anderson Amanda P, Bentley Carol, Hassanali Tasneem, Wiblin Sarah, Maguire Shaun, Pezzella Francesco, Banham Alison H, Li Demin", "reference": { "type": "PubMed", "id": "33836029", "url": "https://pubmed.ncbi.nlm.nih.gov/33836029" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O95219-1", "protein_name": "Sorting nexin-4", "gene_name": "SNX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9ULX6-1", "protein_name": "A-kinase anchor protein 8-like", "gene_name": "AKAP8L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00203-1", "protein_name": "AP-3 complex subunit beta-1", "gene_name": "AP3B1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68036-1", "protein_name": "Ubiquitin-conjugating enzyme E2 L3", "gene_name": "UBE2L3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y483-1", "protein_name": "Metal-response element-binding transcription factor 2", "gene_name": "MTF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92626-1", "protein_name": "Peroxidasin homolog", "gene_name": "PXDN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33993-1", "protein_name": "DNA replication licensing factor MCM7", "gene_name": "MCM7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19544-1", "protein_name": "Wilms tumor protein", "gene_name": "WT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPM6-1", "protein_name": "LIM/homeobox protein Lhx6", "gene_name": "LHX6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y566-1", "protein_name": "SH3 and multiple ankyrin repeat domains protein 1", "gene_name": "SHANK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05923-1", "protein_name": "Dual specificity protein phosphatase 2", "gene_name": "DUSP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P02545-1", "protein_name": "Prelamin-A/C", "gene_name": "LMNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q63ZY3-1", "protein_name": "KN motif and ankyrin repeat domain-containing protein 2", "gene_name": "KANK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR9-1", "protein_name": "Glucose-6-phosphatase 2", "gene_name": "G6PC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P14679-1", "protein_name": "Tyrosinase", "gene_name": "TYR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05783-1", "protein_name": "Keratin, type I cytoskeletal 18", "gene_name": "KRT18", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60885-1", "protein_name": "Bromodomain-containing protein 4", "gene_name": "BRD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95503-1", "protein_name": "Chromobox protein homolog 6", "gene_name": "CBX6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78358-1", "protein_name": "Cancer/testis antigen 1", "gene_name": "CTAG1A; CTAG1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4A5-1", "protein_name": "Transformation/transcription domain-associated protein", "gene_name": "TRRAP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPA5-1", "protein_name": "Protein bassoon", "gene_name": "BSN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y07-1", "protein_name": "Serine/threonine-protein kinase VRK2", "gene_name": "VRK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40967-1", "protein_name": "Melanocyte protein PMEL", "gene_name": "PMEL", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RD6-3", "protein_name": "Pannexin-2", "gene_name": "PANX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z6I6-1", "protein_name": "Rho GTPase-activating protein 30", "gene_name": "ARHGAP30", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00507-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9Y", "gene_name": "USP9Y", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32019-1", "protein_name": "Type II inositol 1,4,5-trisphosphate 5-phosphatase", "gene_name": "INPP5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6KC79-1", "protein_name": "Nipped-B-like protein", "gene_name": "NIPBL", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O95219", "url": "https://www.uniprot.org/uniprotkb/O95219" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.33836029", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 29 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Secretion of lecithin:cholesterol acyltransferase by brain neuroglial cell lines.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1999", "authors": "Collet X, Francone O, Besnard F, Fielding C J", "reference": { "type": "PubMed", "id": "10222237", "url": "https://pubmed.ncbi.nlm.nih.gov/10222237" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10222237", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Binding affinity and reactivity of lecithin cholesterol acyltransferase with native lipoproteins.", "journal": "Biochemical and biophysical research communications", "date": "1999-05-19", "authors": "Kosek A B, Durbin D, Jonas A", "reference": { "type": "PubMed", "id": "10329423", "url": "https://pubmed.ncbi.nlm.nih.gov/10329423" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10329423", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Formation of spherical, reconstituted high density lipoproteins containing both apolipoproteins A-I and A-II is mediated by lecithin:cholesterol acyltransferase.", "journal": "The Journal of biological chemistry", "date": "2000-03-24", "authors": "Clay M A, Pyle D H, Rye K A, Barter P J", "reference": { "type": "PubMed", "id": "10722751", "url": "https://pubmed.ncbi.nlm.nih.gov/10722751" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10722751", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hypocomplementemic type II membranoproliferative glomerulonephritis in a male patient with familial lecithin-cholesterol acyltransferase deficiency due to two different allelic mutations.", "journal": "Nephron", "date": "2001", "authors": "Sessa A, Battini G, Meroni M, Daidone G, Carnera I, Brambilla PL, Vigano G, Giordano F, Pallotti F, Torri Tarelli L, Calabresi L, Rolleri M, Bertolini S", "reference": { "type": "PubMed", "id": "11423760", "url": "https://pubmed.ncbi.nlm.nih.gov/11423760" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11423760", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Serum lysophosphatidic acid is produced through diverse phospholipase pathways.", "journal": "The Journal of biological chemistry", "date": "2002-12-13", "authors": "Aoki Junken, Taira Akitsu, Takanezawa Yasukazu, Kishi Yasuhiro, Hama Kotaro, Kishimoto Tatsuya, Mizuno Koji, Saku Keijiro, Taguchi Ryo, Arai Hiroyuki", "reference": { "type": "PubMed", "id": "12354767", "url": "https://pubmed.ncbi.nlm.nih.gov/12354767" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q64610-1", "protein_name": "Autotaxin", "gene_name": "Enpp2", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q13822-1", "protein_name": "Autotaxin", "gene_name": "ENPP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12354767", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel LCAT mutation (Phe382-->Val) in a kindred with familial LCAT deficiency and defective apolipoprotein B-100.", "journal": "Atherosclerosis", "date": "2003", "authors": "Nanjee MN, Stocks J, Cooke CJ, Molhuizen HO, Marcovina S, Crook D, Kastelein JP, Miller NE", "reference": { "type": "PubMed", "id": "12957688", "url": "https://pubmed.ncbi.nlm.nih.gov/12957688" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12957688", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Negative charge at amino acid 149 is the molecular determinant for substrate specificity of lecithin: cholesterol acyltransferase for phosphatidylcholine containing 20-carbon sn-2 fatty acyl chains.", "journal": "Biochemistry", "date": "2003", "authors": "Zhao Y, Wang J, Gebre AK, Chisholm JW, Parks JS", "reference": { "type": "PubMed", "id": "14636062", "url": "https://pubmed.ncbi.nlm.nih.gov/14636062" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18424-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "Lcat", "tax_name": "Rat" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 173, "end_pos": 173, "sequence_org": "E", "sequence_mut": "A", "comment": "Increased activity towards PAPC. Increased PAPC/POPC activity ratio.", "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" }, { "database": "PubMed", "id": "14636062", "url": "https://pubmed.ncbi.nlm.nih.gov/14636062" } ], "uniprot_canonical_ac": "P04180-1" }, { "start_pos": 173, "end_pos": 173, "sequence_org": "E", "sequence_mut": "D", "comment": "Little change in enzyme specific activity nor in PAPC/POPC activity ratio.", "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" }, { "database": "PubMed", "id": "14636062", "url": "https://pubmed.ncbi.nlm.nih.gov/14636062" } ], "uniprot_canonical_ac": "P04180-1" }, { "start_pos": 173, "end_pos": 173, "sequence_org": "E", "sequence_mut": "K", "comment": "Decreased enzyme specific activity. Increased PAPC/POPC activity ratio.", "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" }, { "database": "PubMed", "id": "14636062", "url": "https://pubmed.ncbi.nlm.nih.gov/14636062" } ], "uniprot_canonical_ac": "P04180-1" }, { "start_pos": 173, "end_pos": 173, "sequence_org": "E", "sequence_mut": "L", "comment": "Increased activity towards PAPC. Increased PAPC/POPC activity ratio.", "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" }, { "database": "PubMed", "id": "14636062", "url": "https://pubmed.ncbi.nlm.nih.gov/14636062" } ], "uniprot_canonical_ac": "P04180-1" }, { "start_pos": 173, "end_pos": 173, "sequence_org": "E", "sequence_mut": "Q", "comment": "Decreased enzyme specific activity. Increased PAPC/POPC activity ratio.", "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" }, { "database": "PubMed", "id": "14636062", "url": "https://pubmed.ncbi.nlm.nih.gov/14636062" } ], "uniprot_canonical_ac": "P04180-1" }, { "start_pos": 173, "end_pos": 173, "sequence_org": "A", "sequence_mut": "E", "comment": "Reduced activity with 20-carbon phosphatidylcholine as substrate. Little change with 18-carbon phosphatidylcholine as substrate.", "evidence": [ { "database": "UniProtKB", "id": "P18424", "url": "https://www.uniprot.org/uniprotkb/P18424" }, { "database": "PubMed", "id": "14636062", "url": "https://pubmed.ncbi.nlm.nih.gov/14636062" } ], "uniprot_canonical_ac": "P18424-1" } ], "record_id": "pubmed.14636062", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The genetic defect of the original Norwegian lecithin:cholesterol acyltransferase deficiency families.", "journal": "FEBS letters", "date": "1992", "authors": "Skretting G, Blomhoff JP, Solheim J, Prydz H", "reference": { "type": "PubMed", "id": "1516702", "url": "https://pubmed.ncbi.nlm.nih.gov/1516702" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1516702", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "An amino acid exchange in exon I of the human lecithin: cholesterol acyltransferase (LCAT) gene is associated with fish eye disease.", "journal": "Biochemical and biophysical research communications", "date": "1992", "authors": "Skretting G, Prydz H", "reference": { "type": "PubMed", "id": "1571050", "url": "https://pubmed.ncbi.nlm.nih.gov/1571050" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1571050", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The molecular basis of lecithin:cholesterol acyltransferase deficiency syndromes: a comprehensive study of molecular and biochemical findings in 13 unrelated Italian families.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2005", "authors": "Calabresi L, Pisciotta L, Costantin A, Frigerio I, Eberini I, Alessandrini P, Arca M, Bon GB, Boscutti G, Busnach G, Frasca G, Gesualdo L, Gigante M, Lupattelli G, Montali A, Pizzolitto S, Rabbone I, Rolleri M, Ruotolo G, Sampietro T, Sessa A, Vaudo G, Cantafora A, Veglia F, Calandra S, Bertolini S, Franceschini G", "reference": { "type": "PubMed", "id": "15994445", "url": "https://pubmed.ncbi.nlm.nih.gov/15994445" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15994445", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Familial lecithin-cholesterol acyltransferase deficiency: biochemical characteristics and molecular analysis of a new LCAT mutation in a Polish family.", "journal": "Atherosclerosis", "date": "2006", "authors": "Idzior-Walus B, Sieradzki J, Kostner G, Malecki MT, Klupa T, Wesolowska T, Rostworowski W, Hartwich J, Walus M, Kiec AD, Naruszewicz M", "reference": { "type": "PubMed", "id": "16051254", "url": "https://pubmed.ncbi.nlm.nih.gov/16051254" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16051254", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Compound heterozygosity (G71R/R140H) in the lecithin:cholesterol acyltransferase (LCAT) gene results in an intermediate phenotype between LCAT-deficiency and fish-eye disease.", "journal": "Atherosclerosis", "date": "2006", "authors": "Horl G, Kroisel PM, Wagner E, Tiran B, Petek E, Steyrer E", "reference": { "type": "PubMed", "id": "16216249", "url": "https://pubmed.ncbi.nlm.nih.gov/16216249" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16216249", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Differential phenotypic expression by three mutant alleles in familial lecithin:cholesterol acyltransferase deficiency.", "journal": "Lancet (London, England)", "date": "1991", "authors": "Gotoda T, Yamada N, Murase T, Sakuma M, Murayama N, Shimano H, Kozaki K, Albers JJ, Yazaki Y, Akanuma Y", "reference": { "type": "PubMed", "id": "1681161", "url": "https://pubmed.ncbi.nlm.nih.gov/1681161" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1681161", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "LCAT deficiency: molecular and phenotypic characterization of an Italian family.", "journal": "Journal of nephrology", "date": "2006", "authors": "Gigante M, Ranieri E, Cerullo G, Calabresi L, Iolascon A, Assmann G, Morrone L, Pisciotta L, Schena FP, Gesualdo L", "reference": { "type": "PubMed", "id": "16874701", "url": "https://pubmed.ncbi.nlm.nih.gov/16874701" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16874701", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Two different allelic mutations in the lecithin-cholesterol acyltransferase gene associated with the fish eye syndrome. Lecithin-cholesterol acyltransferase (Thr123----Ile) and lecithin-cholesterol acyltransferase (Thr347----Met).", "journal": "The Journal of clinical investigation", "date": "1992", "authors": "Klein HG, Lohse P, Pritchard PH, Bojanovski D, Schmidt H, Brewer HB Jr", "reference": { "type": "PubMed", "id": "1737840", "url": "https://pubmed.ncbi.nlm.nih.gov/1737840" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1737840", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Relationship of endogenous hyperleptinemia to serum paraoxonase 1, cholesteryl ester transfer protein, and lecithin cholesterol acyltransferase in obese individuals.", "journal": "Metabolism", "date": "2007", "authors": "Bajnok Laszlo, Seres Ildiko, Varga Zsuzsa, Jeges Sara, Peti Attila, Karanyi Zsolt, Juhasz Attila, Csongradi Eva, Mezosi Emese, Nagy Endre V, Paragh Gyorgy", "reference": { "type": "PubMed", "id": "17950106", "url": "https://pubmed.ncbi.nlm.nih.gov/17950106" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17950106", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Lecithin-cholesterol acyltransferase (LCAT) deficiency with a missense mutation in exon 6 of the LCAT gene.", "journal": "Biochemical and biophysical research communications", "date": "1991", "authors": "Maeda E, Naka Y, Matozaki T, Sakuma M, Akanuma Y, Yoshino G, Kasuga M", "reference": { "type": "PubMed", "id": "1859405", "url": "https://pubmed.ncbi.nlm.nih.gov/1859405" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1859405", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins.", "journal": "Journal of lipid research", "date": "2009", "authors": "Hirsch-Reinshagen V, Donkin J, Stukas S, Chan J, Wilkinson A, Fan J, Parks JS, Kuivenhoven JA, Lutjohann D, Pritchard H, Wellington CL", "reference": { "type": "PubMed", "id": "19065001", "url": "https://pubmed.ncbi.nlm.nih.gov/19065001" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16301-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "Lcat", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19065001", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "High prevalence of mutations in LCAT in patients with low HDL cholesterol levels in The Netherlands: identification and characterization of eight novel mutations.", "journal": "Human mutation", "date": "2011", "authors": "Holleboom AG, Kuivenhoven JA, Peelman F, Schimmel AW, Peter J, Defesche JC, Kastelein JJ, Hovingh GK, Stroes ES, Motazacker MM", "reference": { "type": "PubMed", "id": "21901787", "url": "https://pubmed.ncbi.nlm.nih.gov/21901787" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21901787", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Lecithin cholesterol acyl transferase deficiency: molecular analysis of a mutated allele.", "journal": "Human genetics", "date": "1990", "authors": "Taramelli R, Pontoglio M, Candiani G, Ottolenghi S, Dieplinger H, Catapano A, Albers J, Vergani C, McLean J", "reference": { "type": "PubMed", "id": "2370048", "url": "https://pubmed.ncbi.nlm.nih.gov/2370048" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2370048", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The enzyme lecithin-cholesterol acyltransferase esterifies cerebrosterol and limits the toxic effect of this oxysterol on SH-SY5Y cells.", "journal": "Journal of neurochemistry", "date": "2014", "authors": "La Marca V, Spagnuolo MS, Cigliano L, Marasco D, Abrescia P", "reference": { "type": "PubMed", "id": "24620755", "url": "https://pubmed.ncbi.nlm.nih.gov/24620755" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.24620755", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure and function of lysosomal phospholipase A2 and lecithin:cholesterol acyltransferase.", "journal": "Nat. Commun.", "date": "2015", "authors": "Glukhova A, Hinkovska-Galcheva V, Kelly R, Abe A, Shayman JA, Tesmer JJ", "reference": { "type": "PubMed", "id": "25727495", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NCC3-1", "protein_name": "Lysosomal phospholipase A and acyltransferase", "gene_name": "PLA2G15", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X90&bu=0&command=select+.B:240;+center+selection;+zoom+selection" }, "start_pos": 273, "start_aa": "Asn", "end_pos": 273, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn273", "evidence": [ { "id": "29741879", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/29741879" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": "http://data.glygen.org/GLY_000040" }, { "id": "Q8NCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3#ptm_processing" }, { "id": "4X93", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X93" }, { "id": "4X91", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X91" }, { "id": "4X95", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X95" }, { "id": "4X94", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X94" }, { "id": "25727495", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" }, { "id": "4X90", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X90" }, { "id": "4X92", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X92" }, { "id": "4X97", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X97" }, { "id": "24190977", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/24190977" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" } ], "filter_code": "001000000000000000000.00010000000000.00.01101", "uniprot_canonical_ac": "Q8NCC3-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X90&bu=0&command=select+.B:256;+center+selection;+zoom+selection" }, "start_pos": 289, "start_aa": "Asn", "end_pos": 289, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn289", "evidence": [ { "id": "Q8NCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3#ptm_processing" }, { "id": "4X90", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X90" }, { "id": "4X97", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X97" }, { "id": "4X92", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X92" }, { "id": "25727495", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" }, { "id": "4X91", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X91" }, { "id": "4X95", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X95" }, { "id": "4X93", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X93" }, { "id": "4X94", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X94" }, { "id": "23090970", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/23090970" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" }, { "id": "24190977", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/24190977" } ], "filter_code": "001000000000000000000.00010000000000.00.01101", "uniprot_canonical_ac": "Q8NCC3-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X90&bu=0&command=select+.B:365;+center+selection;+zoom+selection" }, "start_pos": 398, "start_aa": "Asn", "end_pos": 398, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn398", "evidence": [ { "id": "Q8NCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3#ptm_processing" }, { "id": "25727495", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" }, { "id": "4X95", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X95" }, { "id": "4X97", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X97" }, { "id": "4X91", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X91" }, { "id": "4X90", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X90" }, { "id": "4X94", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X94" }, { "id": "4X92", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X92" }, { "id": "4X93", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X93" }, { "id": "6MTW", "database": "PDB", "url": "https://www.rcsb.org/structure/6MTW" } ], "filter_code": "001000000000000000000.00010000000000.00.01101", "uniprot_canonical_ac": "Q8NCC3-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4X90&bu=0&command=select+.B:66;+center+selection;+zoom+selection" }, "start_pos": 99, "start_aa": "Asn", "end_pos": 99, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn99", "evidence": [ { "id": "Q8NCC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3#ptm_processing" }, { "id": "4X90", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X90" }, { "id": "4X95", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X95" }, { "id": "4X92", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X92" }, { "id": "25727495", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" }, { "id": "4X94", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X94" }, { "id": "4X93", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X93" }, { "id": "4X97", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X97" }, { "id": "4X91", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X91" }, { "id": "6MTW", "database": "PDB", "url": "https://www.rcsb.org/structure/6MTW" } ], "filter_code": "001000000000000000000.00010000000000.00.01100", "uniprot_canonical_ac": "Q8NCC3-1" } ], "mutagenesis": [ { "start_pos": 198, "end_pos": 198, "sequence_org": "S", "sequence_mut": "A", "comment": "Abolishes phospholipase and transacylase activity. Abolishes association with membranes.", "evidence": [ { "database": "UniProtKB", "id": "Q8NCC3", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3" }, { "database": "PubMed", "id": "25727495", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" } ], "uniprot_canonical_ac": "Q8NCC3-1" }, { "start_pos": 235, "end_pos": 235, "sequence_org": "K", "sequence_mut": "A", "comment": "No effect on phospholipase activity. Abolishes transacylase activity. Has no effect on association with membranes.", "evidence": [ { "database": "UniProtKB", "id": "Q8NCC3", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3" }, { "database": "PubMed", "id": "25727495", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" } ], "uniprot_canonical_ac": "Q8NCC3-1" }, { "start_pos": 362, "end_pos": 362, "sequence_org": "T", "sequence_mut": "A", "comment": "No effect on phospholipase activity. Strongly decreases transacylase activity and abolishes association with membranes.", "evidence": [ { "database": "UniProtKB", "id": "Q8NCC3", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3" }, { "database": "PubMed", "id": "25727495", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" } ], "uniprot_canonical_ac": "Q8NCC3-1" }, { "start_pos": 46, "end_pos": 46, "sequence_org": "D", "sequence_mut": "A", "comment": "Decreases membrane binding, phospholipase and transacylase activity at acidic pH.", "evidence": [ { "database": "UniProtKB", "id": "Q8NCC3", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3" }, { "database": "PubMed", "id": "25727495", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" }, { "database": "PubMed", "id": "29724779", "url": "https://pubmed.ncbi.nlm.nih.gov/29724779" } ], "uniprot_canonical_ac": "Q8NCC3-1" }, { "start_pos": 46, "end_pos": 46, "sequence_org": "D", "sequence_mut": "C", "comment": "Decreases membrane binding, phospholipase and transacylase activity at acidic pH.", "evidence": [ { "database": "UniProtKB", "id": "Q8NCC3", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3" }, { "database": "PubMed", "id": "25727495", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" }, { "database": "PubMed", "id": "29724779", "url": "https://pubmed.ncbi.nlm.nih.gov/29724779" } ], "uniprot_canonical_ac": "Q8NCC3-1" }, { "start_pos": 83, "end_pos": 83, "sequence_org": "L", "sequence_mut": "S", "comment": "No effect on phospholipase activity. Strongly decreases transacylase activity and association with membranes.", "evidence": [ { "database": "UniProtKB", "id": "Q8NCC3", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3" }, { "database": "PubMed", "id": "25727495", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" } ], "uniprot_canonical_ac": "Q8NCC3-1" }, { "start_pos": 85, "end_pos": 85, "sequence_org": "V", "sequence_mut": "S", "comment": "No effect on phospholipase activity. Strongly decreases transacylase activity and association with membranes.", "evidence": [ { "database": "UniProtKB", "id": "Q8NCC3", "url": "https://www.uniprot.org/uniprotkb/Q8NCC3" }, { "database": "PubMed", "id": "25727495", "url": "https://pubmed.ncbi.nlm.nih.gov/25727495" } ], "uniprot_canonical_ac": "Q8NCC3-1" } ], "record_id": "pubmed.25727495", "abstract": "", "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 4 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_n_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 4 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_n_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The high-resolution crystal structure of human LCAT.", "journal": "Journal of lipid research", "date": "2015", "authors": "Piper DE, Romanow WG, Gunawardane RN, Fordstrom P, Masterman S, Pan O, Thibault ST, Zhang R, Meininger D, Schwarz M, Wang Z, King C, Zhou M, Walker NP", "reference": { "type": "PubMed", "id": "26195816", "url": "https://pubmed.ncbi.nlm.nih.gov/26195816" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine;Complex", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4XWG&bu=0&command=select+.A:84;+center+selection;+zoom+selection" }, "start_pos": 108, "start_aa": "Asn", "end_pos": 108, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn108", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "26195816", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/26195816" }, { "id": "4X96", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X96" }, { "id": "4XWG", "database": "PDB", "url": "https://www.rcsb.org/structure/4XWG" }, { "id": "4XX1", "database": "PDB", "url": "https://www.rcsb.org/structure/4XX1" }, { "id": "5BV7", "database": "PDB", "url": "https://www.rcsb.org/structure/5BV7" }, { "id": "6MVD", "database": "PDB", "url": "https://www.rcsb.org/structure/6MVD" } ], "filter_code": "001000000000000000000.10000000000000.00.01001", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine;Complex", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4XWG&bu=0&command=select+.A:272;+center+selection;+zoom+selection" }, "start_pos": 296, "start_aa": "Asn", "end_pos": 296, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn296", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "16335952", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/16335952" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "26195816", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/26195816" }, { "id": "4X96", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X96" }, { "id": "23090970", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/23090970" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" }, { "id": "4XWG", "database": "PDB", "url": "https://www.rcsb.org/structure/4XWG" }, { "id": "4XX1", "database": "PDB", "url": "https://www.rcsb.org/structure/4XX1" }, { "id": "5TXF", "database": "PDB", "url": "https://www.rcsb.org/structure/5TXF" }, { "id": "6MVD", "database": "PDB", "url": "https://www.rcsb.org/structure/6MVD" } ], "filter_code": "001000000000000000000.10000000000000.00.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine;Complex", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4XWG&bu=0&command=select+.A:384;+center+selection;+zoom+selection" }, "start_pos": 408, "start_aa": "Asn", "end_pos": 408, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn408", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "26195816", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/26195816" }, { "id": "4X96", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X96" }, { "id": "4XWG", "database": "PDB", "url": "https://www.rcsb.org/structure/4XWG" }, { "id": "4XX1", "database": "PDB", "url": "https://www.rcsb.org/structure/4XX1" }, { "id": "5BV7", "database": "PDB", "url": "https://www.rcsb.org/structure/5BV7" }, { "id": "6MVD", "database": "PDB", "url": "https://www.rcsb.org/structure/6MVD" } ], "filter_code": "001000000000000000000.10000000000000.00.01001", "uniprot_canonical_ac": "P04180-1" } ], "record_id": "pubmed.26195816", "abstract": "", "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 3 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_n_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 3 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_n_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "filter_code", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The isolation and characterisation of a cDNA clone for human lecithin:cholesterol acyl transferase and its use to analyse the genes in patients with LCAT deficiency and fish eye disease.", "journal": "Biochem. Biophys. Res. Commun.", "date": "1987", "authors": "Rogne S, Skretting G, Larsen F, Myklebost O, Mev\u00e5g B, Carlson L A, Holmquist L, Gjone E, Prydz H", "reference": { "type": "PubMed", "id": "2823801", "url": "https://pubmed.ncbi.nlm.nih.gov/2823801" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2823801", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The isolation and characterisation of cDNA and genomic clones for human lecithin: cholesterol acyltransferase.", "journal": "Biochim. Biophys. Acta", "date": "1987", "authors": "Tata F, Chaves M E, Markham A F, Scrace G D, Waterfield M D, McIntyre N, Williamson R, Humphries S E", "reference": { "type": "PubMed", "id": "2823898", "url": "https://pubmed.ncbi.nlm.nih.gov/2823898" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2823898", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Lecithin:cholesterol acyltransferase. Functional regions and a structural model of the enzyme.", "journal": "J. Biol. Chem.", "date": "1987", "authors": "Yang C Y, Manoogian D, Pao Q, Lee F S, Knapp R D, Gotto A M, Pownall H J", "reference": { "type": "PubMed", "id": "2880847", "url": "https://pubmed.ncbi.nlm.nih.gov/2880847" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.2880847", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "LCAT deficiency: a systematic review with the clinical and genetic description of Mexican kindred.", "journal": "Lipids in health and disease", "date": "2021", "authors": "Mehta R, Elias-Lopez D, Martagon AJ, Perez-Mendez OA, Sanchez MLO, Segura Y, Tusie MT, Aguilar-Salinas CA", "reference": { "type": "PubMed", "id": "34256778", "url": "https://pubmed.ncbi.nlm.nih.gov/34256778" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34256778", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Cloning and expression of human lecithin-cholesterol acyltransferase cDNA.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "1986", "authors": "McLean J, Fielding C, Drayna D, Dieplinger H, Baer B, Kohr W, Henzel W, Lawn R", "reference": { "type": "PubMed", "id": "3458198", "url": "https://pubmed.ncbi.nlm.nih.gov/3458198" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.3458198", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Altered HDL proteome predicts incident CVD in chronic kidney disease patients.", "journal": "Journal of lipid research", "date": "2021", "authors": "Shao B, Mathew AV, Thornock C, Pennathur S", "reference": { "type": "PubMed", "id": "34634315", "url": "https://pubmed.ncbi.nlm.nih.gov/34634315" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15166-1", "protein_name": "Serum paraoxonase/lactonase 3", "gene_name": "PON3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34634315", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Plasma FA composition in familial LCAT deficiency indicates SOAT2-derived cholesteryl ester formation in humans.", "journal": "Journal of lipid research", "date": "2022", "authors": "Pavanello C, Ossoli A, Strazzella A, Rise P, Veglia F, Lhomme M, Parini P, Calabresi L", "reference": { "type": "PubMed", "id": "35598637", "url": "https://pubmed.ncbi.nlm.nih.gov/35598637" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.35598637", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Rapidly progressive renal failure to reveal LCAT deficiency in an Algerian family.", "journal": "Clinical nephrology", "date": "2022-11-24", "authors": "Khellaf Ghalia, Benziane Ali, Kaci Louiza, Missoum Soumia, Lahmar Mourad, Benabadji Mohamed", "reference": { "type": "PubMed", "id": "36420900", "url": "https://pubmed.ncbi.nlm.nih.gov/36420900" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36420900", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human lecithin-cholesterol acyltransferase gene: complete gene sequence and sites of expression.", "journal": "Nucleic Acids Res.", "date": "1986", "authors": "McLean J, Wion K, Drayna D, Fielding C, Lawn R", "reference": { "type": "PubMed", "id": "3797244", "url": "https://pubmed.ncbi.nlm.nih.gov/3797244" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.3797244", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Low LCAT activity is linked to acute decompensated heart failure and mortality in patients with CKD.", "journal": "Journal of lipid research", "date": "2024-09", "authors": "Stadler Julia T, B\u00e4rnthaler Thomas, Borenich Andrea, Emrich Insa E, Habisch Hansj\u00f6rg, Rani Alankrita, Holzer Michael, Madl Tobias, Heine Gunnar H, Marsche Gunther", "reference": { "type": "PubMed", "id": "39154733", "url": "https://pubmed.ncbi.nlm.nih.gov/39154733" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.39154733", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A single G to A nucleotide transition in exon IV of the lecithin: cholesterol acyltransferase (LCAT) gene results in an Arg140 to His substitution and causes LCAT-deficiency.", "journal": "Human genetics", "date": "1995", "authors": "Steyrer E, Haubenwallner S, Horl G, Giessauf W, Kostner GM, Zechner R", "reference": { "type": "PubMed", "id": "7607641", "url": "https://pubmed.ncbi.nlm.nih.gov/7607641" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7607641", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Site-specific detection and structural characterization of the glycosylation of human plasma proteins lecithin:cholesterol acyltransferase and apolipoprotein D using HPLC/electrospray mass spectrometry and sequential glycosidase digestion.", "journal": "Protein science : a publication of the Protein Society", "date": "1995", "authors": "Schindler PA, Settineri CA, Collet X, Fielding CJ, Burlingame AL", "reference": { "type": "PubMed", "id": "7613477", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, "referenced_glycans": [ { "glytoucan_ac": "G36839GD" }, { "glytoucan_ac": "G84467IZ" } ], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05090-1", "protein_name": "Apolipoprotein D", "gene_name": "APOD", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine;Complex", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4XWG&bu=0&command=select+.A:84;+center+selection;+zoom+selection" }, "start_pos": 108, "start_aa": "Asn", "end_pos": 108, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn108", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "26195816", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/26195816" }, { "id": "4X96", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X96" }, { "id": "4XWG", "database": "PDB", "url": "https://www.rcsb.org/structure/4XWG" }, { "id": "4XX1", "database": "PDB", "url": "https://www.rcsb.org/structure/4XX1" }, { "id": "5BV7", "database": "PDB", "url": "https://www.rcsb.org/structure/5BV7" }, { "id": "6MVD", "database": "PDB", "url": "https://www.rcsb.org/structure/6MVD" } ], "filter_code": "001000000000000000000.10000000000000.00.01001", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine;Complex", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4XWG&bu=0&command=select+.A:272;+center+selection;+zoom+selection" }, "start_pos": 296, "start_aa": "Asn", "end_pos": 296, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn296", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "16335952", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/16335952" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "26195816", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/26195816" }, { "id": "4X96", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X96" }, { "id": "23090970", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/23090970" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" }, { "id": "4XWG", "database": "PDB", "url": "https://www.rcsb.org/structure/4XWG" }, { "id": "4XX1", "database": "PDB", "url": "https://www.rcsb.org/structure/4XX1" }, { "id": "5TXF", "database": "PDB", "url": "https://www.rcsb.org/structure/5TXF" }, { "id": "6MVD", "database": "PDB", "url": "https://www.rcsb.org/structure/6MVD" } ], "filter_code": "001000000000000000000.10000000000000.00.01000", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine;Complex", "icn3d_view": { "label": "iCn3D", "url": "https://www.ncbi.nlm.nih.gov/Structure/icn3d/?bcifid=4XWG&bu=0&command=select+.A:384;+center+selection;+zoom+selection" }, "start_pos": 408, "start_aa": "Asn", "end_pos": 408, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn408", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "26195816", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/26195816" }, { "id": "4X96", "database": "PDB", "url": "https://www.rcsb.org/sequence/4X96" }, { "id": "4XWG", "database": "PDB", "url": "https://www.rcsb.org/structure/4XWG" }, { "id": "4XX1", "database": "PDB", "url": "https://www.rcsb.org/structure/4XX1" }, { "id": "5BV7", "database": "PDB", "url": "https://www.rcsb.org/structure/5BV7" }, { "id": "6MVD", "database": "PDB", "url": "https://www.rcsb.org/structure/6MVD" } ], "filter_code": "001000000000000000000.10000000000000.00.01001", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GalNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "T", "relation": "attached", "comment": "O-linked (GalNAc...) threonine;O-GalNAcylation", "icn3d_view": {}, "start_pos": 431, "start_aa": "Thr", "end_pos": 431, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr431", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" } ], "filter_code": "000000000000000010000.00000010000000.00.01001", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "O-GalNAcylation", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "S", "relation": "attached", "comment": "O-linked (GalNAc...) serine;O-GalNAcylation", "icn3d_view": {}, "start_pos": 433, "start_aa": "Ser", "end_pos": 433, "end_aa": "Ser", "residue": "Ser", "site_lbl": "Ser433", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" } ], "filter_code": "000000000000000100000.00000010000000.00.01001", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine;Complex", "icn3d_view": {}, "start_pos": 44, "start_aa": "Asn", "end_pos": 44, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn44", "evidence": [ { "id": "P04180", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P04180#ptm_processing" }, { "id": "16335952", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/16335952" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "23090970", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/23090970" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" }, { "id": "24190977", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/24190977" } ], "filter_code": "001000000000000000000.10000000000000.00.01001", "uniprot_canonical_ac": "P04180-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "Complex", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) (complex) asparagine;Complex", "icn3d_view": {}, "start_pos": 65, "start_aa": "Asn", "end_pos": 65, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn65", "evidence": [ { "id": "P05090", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05090#ptm_processing" }, { "id": "19159218", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/19159218" }, { "id": "7918467", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7918467" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "22171320", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/22171320" }, { "id": "24190977", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/24190977" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" } ], "filter_code": "001000000000000000000.10000000000000.00.01000", "uniprot_canonical_ac": "P05090-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "automatic_literature_mining", "site_category_dict": { "automatic_literature_mining": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Asn", "end_pos": 78, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn78", "evidence": [ { "id": "7918467", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7918467" }, { "id": "GLY_000481", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000481" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" } ], "mining_tool": "GlycoSiteMiner_1.0", "mining_tool_list": [ { "label": "GlycoSiteMiner_1.0" } ], "filter_code": "001000000000000000000.00010000000000.00.01000", "uniprot_canonical_ac": "P05090-1" }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "other", "prediction_tool_list": [], "site_category": "reported", "site_category_dict": { "reported": true }, "site_seq": "N", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 98, "start_aa": "Asn", "end_pos": 98, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn98", "evidence": [ { "id": "19838169", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/19838169" }, { "id": "GLY_000040", "database": "UniCarbKB", "url": "http://data.glygen.org/GLY_000040" }, { "id": "P05090", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/P05090#ptm_processing" }, { "id": "19159218", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/19159218" }, { "id": "7918467", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7918467" }, { "id": "14760718", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/14760718" }, { "id": "16335952", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/16335952" }, { "id": "7613477", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/7613477" }, { "id": "19139490", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/19139490" }, { "id": "22171320", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/22171320" }, { "id": "24190977", "database": "PubMed", "url": "https://pubmed.ncbi.nlm.nih.gov/24190977" }, { "id": "GLY_000143", "database": "GlyGen", "url": "https://data.glygen.org/GLY_000143" } ], "filter_code": "001000000000000000000.00010000000000.00.01001", "uniprot_canonical_ac": "P05090-1" } ], "glycan_expression": [ { "glytoucan_ac": "G84467IZ", "abundance": "", "tissue": { "name": "blood plasma", "namespace": "UBERON", "id": "0001969", "url": "http://purl.obolibrary.org/obo/UBERON_0001969" }, "species": { "name": "Gallus gallus", "taxid": 9031, "reference_species": "Gallus gallus [9031]", "common_name": "Chicken", "glygen_name": "Chicken" }, "cell_line": {} } ], "record_id": "pubmed.7613477", "abstract": "", "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "glytoucan_ac" ] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 9 }, { "field": "total_sites", "count": 9 }, { "field": "n_linked_sites", "count": 7 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 9 }, { "field": "exact_n_linked_sites", "count": 7 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "filter_code", "uniprot_canonical_ac", "mining_tool" ] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 8 }, { "field": "total_sites", "count": 8 }, { "field": "n_linked_sites", "count": 6 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 8 }, { "field": "exact_n_linked_sites", "count": 6 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "filter_code", "uniprot_canonical_ac", "mining_tool" ] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 1 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_n_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "icn3d_view.label", "icn3d_view.url", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl", "filter_code", "uniprot_canonical_ac", "mining_tool" ] } ] }, { "title": "Deficiency of lecithin:cholesterol acyltransferase due to compound heterozygosity of two novel mutations (Gly33Arg and 30 bp ins) in the LCAT gene.", "journal": "Human molecular genetics", "date": "1995", "authors": "Wiebusch H, Cullen P, Owen JS, Collins D, Sharp PS, Funke H, Assmann G", "reference": { "type": "PubMed", "id": "7711728", "url": "https://pubmed.ncbi.nlm.nih.gov/7711728" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7711728", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Hydrolysis and transesterification of platelet-activating factor by lecithin-cholesterol acyltransferase.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "1994-06-21", "authors": "Liu M, Subbaiah P V", "reference": { "type": "PubMed", "id": "8016111", "url": "https://pubmed.ncbi.nlm.nih.gov/8016111" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8016111", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Lecithin:cholesterol acyltransferase deficiency: identification of a causative gene mutation and a co-inherited protein polymorphism.", "journal": "Biochimica et biophysica acta", "date": "1993", "authors": "Hill JS, O K, Wang X, Pritchard PH", "reference": { "type": "PubMed", "id": "8318557", "url": "https://pubmed.ncbi.nlm.nih.gov/8318557" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8318557", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Genetic and phenotypic heterogeneity in familial lecithin: cholesterol acyltransferase (LCAT) deficiency. Six newly identified defective alleles further contribute to the structural heterogeneity in this disease.", "journal": "The Journal of clinical investigation", "date": "1993", "authors": "Funke H, von Eckardstein A, Pritchard PH, Hornby AE, Wiebusch H, Motti C, Hayden MR, Dachet C, Jacotot B, Gerdes U, et al.", "reference": { "type": "PubMed", "id": "8432868", "url": "https://pubmed.ncbi.nlm.nih.gov/8432868" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8432868", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Two different allelic mutations in the lecithin:cholesterol acyltransferase (LCAT) gene resulting in classic LCAT deficiency: LCAT (tyr83-->stop) and LCAT (tyr156-->asn).", "journal": "Journal of lipid research", "date": "1993-01", "authors": "Klein H G, Lohse P, Duverger N, Albers J J, Rader D J, Zech L A, Santamarina-Fojo S, Brewer H B", "reference": { "type": "PubMed", "id": "8445342", "url": "https://pubmed.ncbi.nlm.nih.gov/8445342" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8445342", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Two novel molecular defects in the LCAT gene are associated with fish eye disease.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "1996", "authors": "Kuivenhoven JA, Stalenhoef AF, Hill JS, Demacker PN, Errami A, Kastelein JJ, Pritchard PH", "reference": { "type": "PubMed", "id": "8620346", "url": "https://pubmed.ncbi.nlm.nih.gov/8620346" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8620346", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Complete deficiency of plasma lecithin-cholesterol acyltransferase (LCAT) activity due to a novel homozygous mutation (Gly-30-Ser) in the LCAT gene.", "journal": "Human mutation", "date": "1996", "authors": "Owen JS, Wiebusch H, Cullen P, Watts GF, Lima VL, Funke H, Assmann G", "reference": { "type": "PubMed", "id": "8807342", "url": "https://pubmed.ncbi.nlm.nih.gov/8807342" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P04180-1", "protein_name": "Phosphatidylcholine-sterol acyltransferase", "gene_name": "LCAT", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P04180", "url": "https://www.uniprot.org/uniprotkb/P04180" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8807342", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] } ]