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"gene_name": "MPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DKB6-1", "protein_name": "Mitochondrial pyruvate carrier 1-like protein", "gene_name": "MPC1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07195-1", "protein_name": "L-lactate dehydrogenase B chain", "gene_name": "LDHB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZMR3-1", "protein_name": "L-lactate dehydrogenase A-like 6A", "gene_name": "LDHAL6A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07864-1", "protein_name": "L-lactate dehydrogenase C chain", "gene_name": "LDHC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04760-1", "protein_name": "Lactoylglutathione lyase", "gene_name": "GLO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48163-1", "protein_name": "NADP-dependent malic enzyme", "gene_name": "ME1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21796-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "VDAC1", "tax_name": "Human" }, { 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"gene_name": "LDHAL6A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07864-1", "protein_name": "L-lactate dehydrogenase C chain", "gene_name": "LDHC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04760-1", "protein_name": "Lactoylglutathione lyase", "gene_name": "GLO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48163-1", "protein_name": "NADP-dependent malic enzyme", "gene_name": "ME1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P21796-1", "protein_name": "Non-selective voltage-gated ion channel VDAC1", "gene_name": "VDAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11498-1", "protein_name": "Pyruvate carboxylase, mitochondrial", "gene_name": "PC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYZ2-1", "protein_name": "L-lactate dehydrogenase A-like 6B", "gene_name": "LDHAL6B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y5U8-1", "protein_name": "Mitochondrial pyruvate carrier 1", "gene_name": "MPC1", "tax_name": "Human" }, { 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], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The independent effects of cigarette smoking, alcohol consumption, and serum aspartate aminotransferase on the alanine aminotransferase ratio in korean men for the risk for esophageal cancer.", "journal": "Yonsei medical journal", "date": "2010", "authors": "Kimm H, Kim S, Jee SH", "reference": { "type": "PubMed", "id": "20376881", "url": "https://pubmed.ncbi.nlm.nih.gov/20376881" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P24298-1", "protein_name": "Alanine 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that has_material_basis_in Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a subtype of Betacoronavirus pandemicum." }, "name_list": [ "COVID-19", "2019 Novel Coronavirus (2019-nCoV)", "2019-nCoV infection", "COVID19", "SARS-CoV-2 infection", "2019 novel coronavirus infection", "coronavirus disease 2019", "severe acute respiratory syndrome coronavirus 2 infectious disease", "2019 novel coronavirus", "2019-nCoV", "SARS-CoV-2", "SARS-coronavirus 2", "beta-CoV", "beta-CoVs", "betacoronavirus", "severe acute respiratory syndrome coronavirus 2", "-CoV", "-CoVs", "-coronavirus" ], "id_list": [ "DOID:0080600", "MONDO:0100096" ] } }, { "best_biomarker_role": [ "risk" ], "biomarker_canonical_id": "AN6751", "assessed_biomarker_entity": [ "Aspartate aminotransferase, cytoplasmic" ], "biomarker_id": "AN6751-2", "biomarker": [ "increased AST level" ], "condition": { "id": "DOID:5041", "recommended_name": { "id": "DOID:5041", "resource": "Disease Ontology", "url": 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neoplasm", "malignant esophagus tumor", "malignant neoplasm of esophagus", "malignant neoplasm of oesophagus", "malignant neoplasm of the esophagus", "malignant neoplasm of the oesophagus", "malignant oesophagus neoplasm", "malignant oesophagus tumour", "malignant tumor of esophagus", "malignant tumor of the esophagus", "malignant tumour of oesophagus", "malignant tumour of the oesophagus", "oesophagus cancer", "Ca lower third esophagus", "Ca middle third esophagus", "malignant neoplasm of distal third of oesophagus", "malignant neoplasm of lower third of esophagus", "malignant neoplasm of middle third of esophagus", "malignant neoplasm of proximal third of oesophagus", "malignant neoplasm of upper third oesophagus", "malignant tumor of distal third of esophagus", "malignant tumor of proximal third of esophagus", "malignant tumor of the middle third of the esophagus", "malignant tumour of abdominal oesophagus", "malignant tumour of distal third of oesophagus", "malignant tumour of proximal third of oesophagus", "malignant tumour of the middle third of the oesophagus", "Esophageal cancer" ], "id_list": [ "DOID:5041", "MONDO:0007576", "MIM:133239" ] } } ], "record_id": "pubmed.20376881", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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Martin B, Patry L, Nassif C, Dionne-Laporte A, Ospina LH, Lemyre E, Massicotte C, Laframboise R, Maranda B, Labuda D, Decarie JC, Rypens F, Goldsher D, Fallet-Bianco C, Soucy JF, Laberge AM, Maftei C, Boycott K, Brais B, Boucher RM, Rouleau GA, Katsanis N, Majewski J, Elpeleg O, Kukolich MK, Shalev S, Michaud JL", "reference": { "type": "PubMed", "id": "26477546", "url": "https://pubmed.ncbi.nlm.nih.gov/26477546" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P24298-1", "protein_name": "Alanine aminotransferase 1", "gene_name": "GPT", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60308-1", "protein_name": "Centrosomal protein of 104 kDa", "gene_name": "CEP104", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5CZC0-1", "protein_name": "Fibrous sheath-interacting protein 2", "gene_name": "FSIP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6ND36-1", "protein_name": "Protein FAM83G", "gene_name": "FAM83G", "tax_name": "Human" }, { 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[] } ] }, { "title": "Involvement of an active-site Zn2+ ligand in the catalytic mechanism of human glyoxalase I.", "journal": "The Journal of biological chemistry", "date": "1998", "authors": "Ridderstrom M, Cameron AD, Jones TA, Mannervik B", "reference": { "type": "PubMed", "id": "9705294", "url": "https://pubmed.ncbi.nlm.nih.gov/9705294" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P24298-1", "protein_name": "Alanine aminotransferase 1", "gene_name": "GPT", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00338-1", "protein_name": "L-lactate dehydrogenase A chain", "gene_name": "LDHA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95563-1", "protein_name": "Mitochondrial pyruvate carrier 2", "gene_name": "MPC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DKB6-1", "protein_name": "Mitochondrial pyruvate carrier 1-like protein", "gene_name": "MPC1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07195-1", "protein_name": 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Expression and purification from Escherichia coli.", "journal": "The Journal of biological chemistry", "date": "1993", "authors": "Murley LL, Mejia NR, MacKenzie RE", "reference": { "type": "PubMed", "id": "7901203", "url": "https://pubmed.ncbi.nlm.nih.gov/7901203" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19801-1", "protein_name": "Diamine oxidase [copper-containing]", "gene_name": "AOC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96N76-1", "protein_name": "Urocanate hydratase", "gene_name": "UROC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53603-1", "protein_name": "Formimidoyltransferase-cyclodeaminase", "gene_name": "FTCD", "tax_name": "Pig" }, { "uniprot_canonical_ac": "P19113-1", "protein_name": "Histidine decarboxylase", "gene_name": "HDC", "tax_name": "Human" }, { "uniprot_canonical_ac": "A5YM72-1", "protein_name": "Carnosine synthase 1", "gene_name": "CARNS1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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Chem.", "date": "1994", "authors": "Chassande O, Renard S, Barbry P, Lazdunski M", "reference": { "type": "PubMed", "id": "8182053", "url": "https://pubmed.ncbi.nlm.nih.gov/8182053" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P19801-1", "protein_name": "Diamine oxidase [copper-containing]", "gene_name": "AOC1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P19801", "url": "https://www.uniprot.org/uniprotkb/P19801" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.8182053", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "cDNA sequences of variant forms of human placenta diamine oxidase.", "journal": "Biochem. 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ariadne-1: a vital Drosophila gene is required in development and defines a new conserved family of ring-finger proteins.", "journal": "Genetics", "date": "2000", "authors": "Aguilera M, Oliveros M, Martinez-Padron M, Barbas JA, Ferrus A", "reference": { "type": "PubMed", "id": "10880484", "url": "https://pubmed.ncbi.nlm.nih.gov/10880484" }, "referenced_glycans": [], "referenced_proteins": [ { 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Cell Genet.", "date": "2000", "authors": "Tan N G, Ardley H C, Rose S A, Leek J P, Markham A F, Robinson P A", "reference": { "type": "PubMed", "id": "11124525", "url": "https://pubmed.ncbi.nlm.nih.gov/11124525" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1K5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "Arih1", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11124525", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7.", "journal": "The Journal of biological chemistry", "date": "2001", "authors": "Ardley HC, Tan NG, Rose SA, Markham AF, Robinson PA", "reference": { "type": "PubMed", "id": "11278816", "url": "https://pubmed.ncbi.nlm.nih.gov/11278816" }, "referenced_glycans": [], 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"sequence_org": "I", "sequence_mut": "A", "comment": "Loss of interaction with UBE2L3. 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Strongly decreased ability to initiate ubiquitination of cullin-RING complexes.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" }, { "database": "PubMed", "id": "23707686", "url": "https://pubmed.ncbi.nlm.nih.gov/23707686" }, { "database": "PubMed", "id": "27565346", "url": "https://pubmed.ncbi.nlm.nih.gov/27565346" }, { "database": "PubMed", "id": "11278816", "url": "https://pubmed.ncbi.nlm.nih.gov/11278816" } ], "uniprot_canonical_ac": "Q9Y4X5-1" }, { "start_pos": 208, "end_pos": 208, "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of interaction with UBE2L3.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" }, { "database": "PubMed", "id": "11278816", "url": "https://pubmed.ncbi.nlm.nih.gov/11278816" } ], "uniprot_canonical_ac": "Q9Y4X5-1" }, { "start_pos": 208, "end_pos": 208, "sequence_org": "C", "sequence_mut": "H", "comment": "Loss of interaction 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[ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human homologue of ariadne promotes the ubiquitylation of translation initiation factor 4E homologous protein, 4EHP.", "journal": "FEBS letters", "date": "2003", "authors": "Tan NG, Ardley HC, Scott GB, Rose SA, Markham AF, Robinson PA", "reference": { "type": "PubMed", "id": "14623119", "url": "https://pubmed.ncbi.nlm.nih.gov/14623119" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60573-1", "protein_name": "Eukaryotic 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}, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure of the C-terminal RING finger from a RING-IBR-RING/TRIAD motif reveals a novel zinc-binding domain distinct from a RING.", "journal": "Journal of molecular biology", "date": "2004", "authors": "Capili AD, Edghill EL, Wu K, Borden KL", "reference": { "type": "PubMed", "id": "15236971", "url": "https://pubmed.ncbi.nlm.nih.gov/15236971" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 347, "end_pos": 347, 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Abolishes ability to transfer ubiquitin and E3 ubiquitin-protein ligase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" }, { "database": "PubMed", "id": "21532592", "url": "https://pubmed.ncbi.nlm.nih.gov/21532592" }, { "database": "PubMed", "id": "15236971", "url": "https://pubmed.ncbi.nlm.nih.gov/15236971" }, { "database": "PubMed", "id": "24058416", "url": "https://pubmed.ncbi.nlm.nih.gov/24058416" }, { "database": "PubMed", "id": "24076655", "url": "https://pubmed.ncbi.nlm.nih.gov/24076655" } ], "uniprot_canonical_ac": "Q9Y4X5-1" }, { "start_pos": 357, "end_pos": 357, "sequence_org": "C", "sequence_mut": "S", "comment": "Does not affect zinc binding and folding. Abolishes ability to transfer ubiquitin and E3 ubiquitin-protein ligase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" }, { "database": "PubMed", "id": "21532592", "url": "https://pubmed.ncbi.nlm.nih.gov/21532592" }, { "database": "PubMed", "id": "15236971", "url": "https://pubmed.ncbi.nlm.nih.gov/15236971" }, { "database": "PubMed", "id": "24058416", "url": "https://pubmed.ncbi.nlm.nih.gov/24058416" }, { "database": "PubMed", "id": "24076655", "url": "https://pubmed.ncbi.nlm.nih.gov/24076655" } ], "uniprot_canonical_ac": "Q9Y4X5-1" }, { "start_pos": 359, "end_pos": 359, "sequence_org": "H", "sequence_mut": "A", "comment": "Defects in ligation. Does not affect zinc binding, folding. 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Mol. 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Cell Res.", "date": "2013", "authors": "Elmehdawi Fatima, Wheway Gabrielle, Szymanska Katarzyna, Adams Matthew, High Alec S, Johnson Colin A, Robinson Philip A", "reference": { "type": "PubMed", "id": "23059369", "url": "https://pubmed.ncbi.nlm.nih.gov/23059369" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.23059369", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure of HHARI, a RING-IBR-RING ubiquitin ligase: autoinhibition of an Ariadne-family E3 and insights into ligation mechanism.", "journal": "Structure (London, England : 1993)", "date": "2013", "authors": "Duda DM, Olszewski JL, Schuermann JP, Kurinov I, Miller DJ, Nourse A, Alpi AF, Schulman BA", "reference": { "type": "PubMed", "id": "23707686", "url": "https://pubmed.ncbi.nlm.nih.gov/23707686" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 188, "end_pos": 188, "sequence_org": "I", "sequence_mut": "A", "comment": "Loss of interaction with UBE2L3. 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The E3 ubiquitin ligase ARIH1 protects against genotoxic stress by initiating a 4EHP-mediated mRNA translation arrest.", "journal": "Molecular and cellular biology", "date": "2015", "authors": "von Stechow L, Typas D, Carreras Puigvert J, Oort L, Siddappa R, Pines A, Vrieling H, van de Water B, Mullenders LH, Danen EH", "reference": { "type": "PubMed", "id": "25624349", "url": "https://pubmed.ncbi.nlm.nih.gov/25624349" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", 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"Human" }, { "uniprot_canonical_ac": "Q9NZJ5-1", "protein_name": "Eukaryotic translation initiation factor 2-alpha kinase 3", "gene_name": "EIF2AK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40305-2", "protein_name": "Interferon alpha-inducible protein 27, mitochondrial", "gene_name": "IFI27", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13451-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP5", "gene_name": "FKBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53G44-1", "protein_name": "Interferon-induced protein 44-like", "gene_name": "IFI44L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.30169894", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 18 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A CRISPR screen identifies IFI6 as an ER-resident interferon effector that blocks flavivirus replication.", "journal": "Nature microbiology", "date": "2018", "authors": "Richardson RB, Ohlson MB, Eitson JL, Kumar A, McDougal MB, Boys IN, Mar KB, De La Cruz-Rivera PC, Douglas C, Konopka G, Xing C, Schoggins JW", "reference": { "type": "PubMed", "id": "30224801", "url": "https://pubmed.ncbi.nlm.nih.gov/30224801" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11021-1", "protein_name": "Endoplasmic reticulum chaperone BiP", "gene_name": "HSPA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14933-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "UBE2L6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41226-1", "protein_name": "Ubiquitin-like modifier-activating enzyme 7", "gene_name": "UBA7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09912-1", "protein_name": "Interferon alpha-inducible protein 6", "gene_name": "IFI6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18850-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-6 alpha", "gene_name": "ATF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZJ5-1", "protein_name": "Eukaryotic translation initiation factor 2-alpha kinase 3", "gene_name": "EIF2AK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40305-2", "protein_name": "Interferon alpha-inducible protein 27, mitochondrial", "gene_name": "IFI27", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13451-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP5", "gene_name": "FKBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53G44-1", "protein_name": "Interferon-induced protein 44-like", "gene_name": "IFI44L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.30224801", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 18 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Coupled monoubiquitylation of the co-E3 ligase DCNL1 by Ariadne-RBR E3 ubiquitin ligases promotes cullin-RING ligase complex remodeling.", "journal": "The Journal of biological chemistry", "date": "2019", "authors": "Kelsall IR, Kristariyanto YA, Knebel A, Wood NT, Kulathu Y, Alpi AF", "reference": { "type": "PubMed", "id": "30587576", "url": "https://pubmed.ncbi.nlm.nih.gov/30587576" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95376-1", "protein_name": "E3 ubiquitin-protein ligase ARIH2", "gene_name": "ARIH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GG9-1", "protein_name": "DCN1-like protein 1", "gene_name": "DCUN1D1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 15, "end_pos": 15, "sequence_org": "F", "sequence_mut": "A", "comment": "Loss of ubiquitin binding; when associated with A-16, A-44 and A-45.", "evidence": [ { "database": "UniProtKB", "id": "Q96GG9", "url": "https://www.uniprot.org/uniprotkb/Q96GG9" }, { "database": "PubMed", "id": "30587576", "url": "https://pubmed.ncbi.nlm.nih.gov/30587576" } ], "uniprot_canonical_ac": "Q96GG9-1" }, { "start_pos": 16, "end_pos": 16, "sequence_org": "M", "sequence_mut": "A", "comment": "Loss of ubiquitin binding; when associated with A-15, A-44 and A-45.", "evidence": [ { "database": "UniProtKB", "id": "Q96GG9", "url": "https://www.uniprot.org/uniprotkb/Q96GG9" }, { "database": "PubMed", "id": "30587576", "url": "https://pubmed.ncbi.nlm.nih.gov/30587576" } ], "uniprot_canonical_ac": "Q96GG9-1" }, { "start_pos": 211, "end_pos": 211, "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of interaction with CUL1, CUL2, CUL3, CULA4, CULA5 CAND1 and RBX1; when associated with R-235 and A-241. Does not affect both nucleus and cytoplasm localization; when associated with R-235 and A-241. Reduces cullin neddylation; when associated with R-235 and A-241. Loss of interaction with CUL1, CUL2, CUL3, CULA4 and CULA4; when associated with R-235 and A-241. Loss of CUL2 interaction; when associated with R-235 and A-241. Reduces neddylation on CUL2; when associated with R-235 and A-241. Reduces interaction with VHL and HIF1A; when associated with R-235 and A-241. Does not affect interaction with SOCS1; when associated with R-235 and A-241. Does not affect DCUN1D1 monoubiquitylation; when associated with R-235 and A-241.", "evidence": [ { "database": "UniProtKB", "id": "Q96GG9", "url": "https://www.uniprot.org/uniprotkb/Q96GG9" }, { "database": "PubMed", "id": "26906416", "url": "https://pubmed.ncbi.nlm.nih.gov/26906416" }, { "database": "PubMed", "id": "23401859", "url": "https://pubmed.ncbi.nlm.nih.gov/23401859" }, { "database": "PubMed", "id": "30587576", "url": "https://pubmed.ncbi.nlm.nih.gov/30587576" } ], "uniprot_canonical_ac": "Q96GG9-1" }, { "start_pos": 235, "end_pos": 235, "sequence_org": "A", "sequence_mut": "R", "comment": "Loss of interaction with CUL1, CUL2, CUL3, CULA4, CULA5 CAND1 and RBX1; when associated with A-211 and A-241. Does not affect both nucleus and cytoplasm localization; when associated with A-211 and A-241. Reduces cullin neddylation; when associated with A-211 and A-241. Loss of interaction with CUL1, CUL2, CUL3, CULA4 and CULA4; when associated with A-211 and A-241. Loss of CUL2 interaction; when associated with A-211 and A-241. Reduces neddylation on CUL2; when associated with A-211 and A-241. Reduces interaction with VHL and HIF1A; when associated with A-211 and A-241. Does not affect interaction with SOCS1; when associated with A-211 and A-241. Does not affect DCUN1D1 monoubiquitylation; when associated with A-211 and A-241.", "evidence": [ { "database": "UniProtKB", "id": "Q96GG9", "url": "https://www.uniprot.org/uniprotkb/Q96GG9" }, { "database": "PubMed", "id": "26906416", "url": "https://pubmed.ncbi.nlm.nih.gov/26906416" }, { "database": "PubMed", "id": "23401859", "url": "https://pubmed.ncbi.nlm.nih.gov/23401859" }, { "database": "PubMed", "id": "30587576", "url": "https://pubmed.ncbi.nlm.nih.gov/30587576" } ], "uniprot_canonical_ac": "Q96GG9-1" }, { "start_pos": 241, "end_pos": 241, "sequence_org": "D", "sequence_mut": "A", "comment": "Loss of interaction with CUL1, CUL2, CUL3, CULA4, CULA5 CAND1 and RBX1; when associated with A-211 and R-235. Does not affect both nucleus and cytoplasm localization; when associated with A-211 and R-235. Reduces cullin neddylation; when associated with A-211 and R-235. Loss of interaction with CUL1, CUL2, CUL3, CULA4 and CULA4; when associated with A-211 and R-235. Loss of CUL2 interaction; when associated with A-211 and R-235. Reduces neddylation on CUL2; when associated with A-211 and R-235. Reduces interaction with VHL and HIF1A; when associated with A-211 and R-235. Does not affect interaction with SOCS1; when associated with A-211 and R-235. Does not affect DCUN1D1 monoubiquitylation; when associated with A-211 and R-235.", "evidence": [ { "database": "UniProtKB", "id": "Q96GG9", "url": "https://www.uniprot.org/uniprotkb/Q96GG9" }, { "database": "PubMed", "id": "26906416", "url": "https://pubmed.ncbi.nlm.nih.gov/26906416" }, { "database": "PubMed", "id": "23401859", "url": "https://pubmed.ncbi.nlm.nih.gov/23401859" }, { "database": "PubMed", "id": "30587576", "url": "https://pubmed.ncbi.nlm.nih.gov/30587576" } ], "uniprot_canonical_ac": "Q96GG9-1" }, { "start_pos": 44, "end_pos": 44, "sequence_org": "F", "sequence_mut": "A", "comment": "Loss of ubiquitin binding; when associated with A-15, A-16 and A-45.", "evidence": [ { "database": "UniProtKB", "id": "Q96GG9", "url": "https://www.uniprot.org/uniprotkb/Q96GG9" }, { "database": "PubMed", "id": "30587576", "url": "https://pubmed.ncbi.nlm.nih.gov/30587576" } ], "uniprot_canonical_ac": "Q96GG9-1" }, { "start_pos": 45, "end_pos": 45, "sequence_org": "F", "sequence_mut": "A", "comment": "Loss of ubiquitin binding; when associated with A-15, A-16 and A-44.", "evidence": [ { "database": "UniProtKB", "id": "Q96GG9", "url": "https://www.uniprot.org/uniprotkb/Q96GG9" }, { "database": "PubMed", "id": "30587576", "url": "https://pubmed.ncbi.nlm.nih.gov/30587576" } ], "uniprot_canonical_ac": "Q96GG9-1" } ], "record_id": "pubmed.30587576", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"gene_name": "UBE2L6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41226-1", "protein_name": "Ubiquitin-like modifier-activating enzyme 7", "gene_name": "UBA7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09912-1", "protein_name": "Interferon alpha-inducible protein 6", "gene_name": "IFI6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18850-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-6 alpha", "gene_name": "ATF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZJ5-1", "protein_name": "Eukaryotic 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interferon-Induced Protein 44 Interacts with Cellular FK506-Binding Protein 5, Negatively Regulates Host Antiviral Responses, and Supports Virus Replication.", "journal": "mBio", "date": "2019", "authors": "DeDiego ML, Nogales A, Martinez-Sobrido L, Topham DJ", "reference": { "type": "PubMed", "id": "31455651", "url": "https://pubmed.ncbi.nlm.nih.gov/31455651" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11021-1", "protein_name": "Endoplasmic reticulum chaperone BiP", "gene_name": "HSPA5", "tax_name": "Human" }, { 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activation.", "journal": "Frontiers in immunology", "date": "2023", "authors": "Villamayor Laura, Rivero Vanessa, L\u00f3pez-Garc\u00eda Dar\u00edo, Topham David J, Mart\u00ednez-Sobrido Luis, Nogales Aitor, DeDiego Marta L", "reference": { "type": "PubMed", "id": "36793726", "url": "https://pubmed.ncbi.nlm.nih.gov/36793726" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9Y4X5-1", "protein_name": "E3 ubiquitin-protein ligase ARIH1", "gene_name": "ARIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11021-1", "protein_name": "Endoplasmic reticulum chaperone BiP", "gene_name": "HSPA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14933-1", "protein_name": "Ubiquitin/ISG15-conjugating enzyme E2 L6", "gene_name": "UBE2L6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41226-1", "protein_name": "Ubiquitin-like modifier-activating enzyme 7", "gene_name": "UBA7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09912-1", "protein_name": "Interferon alpha-inducible protein 6", "gene_name": "IFI6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18850-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-6 alpha", "gene_name": "ATF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZJ5-1", "protein_name": "Eukaryotic translation initiation factor 2-alpha kinase 3", "gene_name": "EIF2AK3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UII4-1", "protein_name": "E3 ISG15--protein ligase HERC5", "gene_name": "HERC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P40305-2", "protein_name": "Interferon alpha-inducible protein 27, mitochondrial", "gene_name": "IFI27", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13451-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP5", "gene_name": "FKBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53G44-1", "protein_name": "Interferon-induced protein 44-like", "gene_name": "IFI44L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9Y4X5", "url": "https://www.uniprot.org/uniprotkb/Q9Y4X5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.36793726", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 18 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Arf6 guanine nucleotide exchange factor cytohesin-2 binds to CCDC120 and is transported along neurites to mediate neurite growth.", "journal": "The Journal of biological chemistry", "date": "2014", "authors": "Torii T, Miyamoto Y, Tago K, Sango K, Nakamura K, Sanbe A, Tanoue A, Yamauchi J", "reference": { "type": "PubMed", "id": "25326380", "url": "https://pubmed.ncbi.nlm.nih.gov/25326380" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q96HB5-1", "protein_name": "Coiled-coil domain-containing protein 120", "gene_name": "CCDC120", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63034-1", "protein_name": "Cytohesin-2", "gene_name": "Cyth2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q99418-1", "protein_name": "Cytohesin-2", "gene_name": "CYTH2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": 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interacts and associates with RING1 and Bmi1 and has transcriptional repression properties.", "journal": "J. Biol. Chem.", "date": "2000", "authors": "Bardos JI, Saurin AJ, Tissot C, Duprez E, Freemont PS", "reference": { "type": "PubMed", "id": "10825164", "url": "https://pubmed.ncbi.nlm.nih.gov/10825164" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9HC52", "url": "https://www.uniprot.org/uniprotkb/Q9HC52" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10825164", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The ENL moiety of the childhood leukemia-associated MLL-ENL oncoprotein recruits human Polycomb 3.", "journal": "Oncogene", "date": "2001", "authors": "Garcia-Cuellar MP, Zilles O, Schreiner SA, Birke M, Winkler TH, Slany RK", "reference": { "type": "PubMed", "id": "11313972", "url": "https://pubmed.ncbi.nlm.nih.gov/11313972" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42568-1", "protein_name": "Protein AF-9", "gene_name": "MLLT3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9HC52", "url": "https://www.uniprot.org/uniprotkb/Q9HC52" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11313972", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Dnmt3b, de novo DNA methyltransferase, interacts with SUMO-1 and Ubc9 through its N-terminal region and is subject to modification by SUMO-1.", "journal": "Biochemical and biophysical research communications", "date": "2001", "authors": "Kang ES, Park CW, Chung JH", "reference": { "type": "PubMed", "id": "11735126", "url": "https://pubmed.ncbi.nlm.nih.gov/11735126" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P26358-1", "protein_name": "DNA (cytosine-5)-methyltransferase 1", "gene_name": "DNMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K1-1", "protein_name": "DNA (cytosine-5)-methyltransferase 3A", "gene_name": "DNMT3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBC3-1", "protein_name": "DNA (cytosine-5)-methyltransferase 3B", "gene_name": "DNMT3B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9HC52", "url": "https://www.uniprot.org/uniprotkb/Q9HC52" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11735126", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 15 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] } ]