[ { "title": "Daxx-beta and Daxx-gamma, two novel splice variants of the transcriptional co-repressor Daxx.", "journal": "J. Biol. Chem.", "date": "2011", "authors": "Wethkamp Nils, Hanenberg Helmut, Funke Sarah, Suschek Christoph V, Wetzel Wiebke, Heikaus Sebastian, Grinstein Edgar, Ramp Uwe, Engers Rainer, Gabbert Helmut E, Mahotka Csaba", "reference": { "type": "PubMed", "id": "21482821", "url": "https://pubmed.ncbi.nlm.nih.gov/21482821" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21482821", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", 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"gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75376-1", "protein_name": "Nuclear receptor corepressor 1", "gene_name": "NCOR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43237-1", "protein_name": "Cytoplasmic dynein 1 light intermediate chain 2", "gene_name": "DYNC1LI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14204-1", "protein_name": "Cytoplasmic dynein 1 heavy chain 1", "gene_name": "DYNC1H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04908-1", "protein_name": "Histone H2A type 1-B/E", "gene_name": "H2AC4; H2AC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20671-1", "protein_name": "Histone H2A type 1-D", "gene_name": "H2AC7", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The human cytomegalovirus UL11 protein interacts with the receptor tyrosine phosphatase CD45, resulting in functional paralysis of T cells.", "journal": "PLoS pathogens", "date": "2011", "authors": "Gabaev I, Steinbruck L, Pokoyski C, Pich A, Stanton RJ, Schwinzer R, Schulz TF, Jacobs R, Messerle M, Kay-Fedorov PC", "reference": { "type": "PubMed", "id": "22174689", "url": "https://pubmed.ncbi.nlm.nih.gov/22174689" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68363-1", "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "tax_name": 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{ "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": 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"Histone H2A type 2-A", "gene_name": "H2AC18; H2AC19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L7L0-1", "protein_name": "Histone H2A type 3", "gene_name": "H2AC25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUE6-1", "protein_name": "Histone H2A type 2-B", "gene_name": "H2AC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96QV6-1", "protein_name": "Histone H2A type 1-A", "gene_name": "H2AC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99878-1", "protein_name": "Histone H2A type 1-J", "gene_name": "H2AC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22174689", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 101 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"protein_name": "F-box-like/WD repeat-containing protein TBL1XR1", "gene_name": "TBL1XR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13227-1", "protein_name": "G protein pathway suppressor 2", "gene_name": "GPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13409-1", "protein_name": "Cytoplasmic dynein 1 intermediate chain 2", "gene_name": "DYNC1I2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14576-1", "protein_name": "Cytoplasmic dynein 1 intermediate chain 1", "gene_name": "DYNC1I1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6G9-1", "protein_name": "Cytoplasmic dynein 1 light intermediate chain 1", "gene_name": "DYNC1LI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BUF5-1", "protein_name": "Tubulin beta-6 chain", "gene_name": "TUBB6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NNZ2-1", "protein_name": "Tubulin beta 8B", "gene_name": "TUBB8B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3ZCM7-1", "protein_name": "Tubulin beta-8 chain", "gene_name": "TUBB8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04350-1", "protein_name": "Tubulin beta-4A chain", "gene_name": "TUBB4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15379-1", "protein_name": "Histone deacetylase 3", "gene_name": "HDAC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13885-1", "protein_name": "Tubulin beta-2A chain", "gene_name": "TUBB2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0C0S8-1", "protein_name": "Histone H2A type 1", "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P83916-1", "protein_name": "Chromobox protein homolog 1", "gene_name": "CBX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63167-1", "protein_name": "Dynein light chain 1, cytoplasmic", "gene_name": "DYNLL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05556-1", "protein_name": "Integrin beta-1", "gene_name": "ITGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FJ2-1", "protein_name": "Dynein light chain 2, cytoplasmic", "gene_name": "DYNLL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19419-1", "protein_name": "ETS domain-containing protein Elk-1", "gene_name": "ELK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5QNW6-1", "protein_name": "Histone H2B type 2-F", "gene_name": "H2BC18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93077-1", "protein_name": "Histone H2A type 1-C", "gene_name": "H2AC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KK5-1", "protein_name": "Histone H2A type 1-H", "gene_name": "H2AC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75376-1", "protein_name": "Nuclear receptor corepressor 1", "gene_name": "NCOR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43237-1", "protein_name": "Cytoplasmic dynein 1 light intermediate chain 2", "gene_name": "DYNC1LI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14204-1", "protein_name": "Cytoplasmic dynein 1 heavy chain 1", "gene_name": "DYNC1H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04908-1", "protein_name": "Histone H2A type 1-B/E", "gene_name": "H2AC4; H2AC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20671-1", "protein_name": "Histone H2A type 1-D", "gene_name": "H2AC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16777-1", "protein_name": "Histone H2A type 2-C", "gene_name": "H2AC20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6FI13-1", "protein_name": "Histone H2A type 2-A", "gene_name": "H2AC18; H2AC19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L7L0-1", "protein_name": "Histone H2A type 3", "gene_name": "H2AC25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUE6-1", "protein_name": "Histone H2A type 2-B", "gene_name": "H2AC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96QV6-1", "protein_name": "Histone H2A type 1-A", "gene_name": "H2AC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99878-1", "protein_name": "Histone H2A type 1-J", "gene_name": "H2AC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.26572645", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 100 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO5, a novel poly-sumo isoform, regulates pml nuclear bodies.", "journal": "Sci. Rep.", "date": "2016", "authors": "Liang YC, Lee CC, Yao YL, Lai CC, Schmitz ML, Yang WM", "reference": { "type": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "G2XKQ0-1", "protein_name": "Small ubiquitin-related modifier 5", "gene_name": "SUMO1P1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 160, "end_pos": 160, "sequence_org": "K", "sequence_mut": "R", "comment": "Compromised the formation of high molecular weight species of SUMO1P1/SUMO5 conjugation on PML. Loss of 2 sumoylations; when associated with or without R-65. No sumoylation nor nuclear body formation; when associated with or without R-65 and R-490. Loss the ability to be conjugated by SUMO1P1/SUMO5 but could be conjugated by SUMO1; when associated with R-65 and R-490.", "evidence": [ { "database": "UniProtKB", "id": "P29590", "url": "https://www.uniprot.org/uniprotkb/P29590" }, { "database": "PubMed", "id": "9756909", "url": "https://pubmed.ncbi.nlm.nih.gov/9756909" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "P29590-1" }, { "start_pos": 380, "end_pos": 380, "sequence_org": "K", "sequence_mut": "R", "comment": "Does not affect SUMO1P1/SUMO5 conjugation.", "evidence": [ { "database": "UniProtKB", "id": "P29590", "url": "https://www.uniprot.org/uniprotkb/P29590" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "P29590-1" }, { "start_pos": 400, "end_pos": 400, "sequence_org": "K", "sequence_mut": "R", "comment": "Does not affect SUMO1P1/SUMO5 conjugation.", "evidence": [ { "database": "UniProtKB", "id": "P29590", "url": "https://www.uniprot.org/uniprotkb/P29590" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "P29590-1" }, { "start_pos": 490, "end_pos": 490, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolished conjugation of one SUMO1P1/SUMO5. Loss of 2 sumoylations; when associated with R-65 with or without R-133. No effect on nuclear body formation; when associated with R-65. No sumoylation nor nuclear body formation; when associated with R-65 and R-160. Loss the ability to be conjugated by SUMO1P1/SUMO5 but could be conjugated by SUMO1; when associated with R-65 and R-160.", "evidence": [ { "database": "UniProtKB", "id": "P29590", "url": "https://www.uniprot.org/uniprotkb/P29590" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" }, { "database": "PubMed", "id": "18298799", "url": "https://pubmed.ncbi.nlm.nih.gov/18298799" }, { "database": "PubMed", "id": "9756909", "url": "https://pubmed.ncbi.nlm.nih.gov/9756909" } ], "uniprot_canonical_ac": "P29590-1" }, { "start_pos": 497, "end_pos": 497, "sequence_org": "K", "sequence_mut": "R", "comment": "Does not affect SUMO1P1/SUMO5 conjugation.", "evidence": [ { "database": "UniProtKB", "id": "P29590", "url": "https://www.uniprot.org/uniprotkb/P29590" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "P29590-1" }, { "start_pos": 65, "end_pos": 65, "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of one sumoylation. No effect on nuclear body formation. Loss of 2 sumoylations; when associated with R-490 with or without R-133 or R-150. No effect on nuclear body formation; when associated with R-490. No sumoylation nor nuclear body formation; when associated with R-160 and R-490.", "evidence": [ { "database": "UniProtKB", "id": "P29590", "url": "https://www.uniprot.org/uniprotkb/P29590" }, { "database": "PubMed", "id": "9756909", "url": "https://pubmed.ncbi.nlm.nih.gov/9756909" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "P29590-1" }, { "start_pos": 12, "end_pos": 12, "sequence_org": "H", "sequence_mut": "D", "comment": "Does not affect nuclear bodies formation.", "evidence": [ { "database": "UniProtKB", "id": "G2XKQ0", "url": "https://www.uniprot.org/uniprotkb/G2XKQ0" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "G2XKQ0-1" }, { "start_pos": 17, "end_pos": 21, "sequence_org": "IKDED", "sequence_mut": "KEGEY", "comment": "Unable to form nuclear bodies.", "evidence": [ { "database": "UniProtKB", "id": "G2XKQ0", "url": "https://www.uniprot.org/uniprotkb/G2XKQ0" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "G2XKQ0-1" }, { "start_pos": 18, "end_pos": 18, "sequence_org": "K", "sequence_mut": "R", "comment": "Unable to form nuclear bodies.", "evidence": [ { "database": "UniProtKB", "id": "G2XKQ0", "url": "https://www.uniprot.org/uniprotkb/G2XKQ0" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "G2XKQ0-1" }, { "start_pos": 95, "end_pos": 95, "sequence_org": "I", "sequence_mut": "T", "comment": "Does not affect nuclear bodies formatiom.", "evidence": [ { "database": "UniProtKB", "id": "G2XKQ0", "url": "https://www.uniprot.org/uniprotkb/G2XKQ0" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "G2XKQ0-1" }, { "start_pos": 96, "end_pos": 97, "sequence_org": "GG", "sequence_mut": "AA", "comment": "Lost the ability to conjugate UBE2I. Unable to form nuclear bodies.", "evidence": [ { "database": "UniProtKB", "id": "G2XKQ0", "url": "https://www.uniprot.org/uniprotkb/G2XKQ0" }, { "database": "PubMed", "id": "27211601", "url": "https://pubmed.ncbi.nlm.nih.gov/27211601" } ], "uniprot_canonical_ac": "G2XKQ0-1" } ], "record_id": "pubmed.27211601", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Human Cytomegalovirus Latency: Approaching the Gordian Knot.", "journal": "Annual review of virology", "date": "2016", "authors": "Goodrum F", "reference": { "type": "PubMed", "id": "27501258", "url": "https://pubmed.ncbi.nlm.nih.gov/27501258" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68363-1", "protein_name": "Tubulin alpha-1B chain", "gene_name": "TUBA1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PEY2-1", "protein_name": "Tubulin alpha-3E chain", "gene_name": "TUBA3E", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68366-1", "protein_name": "Tubulin alpha-4A chain", "gene_name": "TUBA4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71U36-1", "protein_name": "Tubulin alpha-1A chain", "gene_name": "TUBA1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", 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"P0C0S8-1", "protein_name": "Histone H2A type 1", "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P83916-1", "protein_name": "Chromobox protein homolog 1", "gene_name": "CBX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63167-1", "protein_name": "Dynein light chain 1, cytoplasmic", "gene_name": "DYNLL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05556-1", "protein_name": "Integrin beta-1", "gene_name": "ITGB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH8-1", "protein_name": "Tubulin alpha-3D chain", "gene_name": "TUBA3D", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96FJ2-1", "protein_name": "Dynein light chain 2, cytoplasmic", "gene_name": "DYNLL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19419-1", "protein_name": "ETS domain-containing protein Elk-1", "gene_name": "ELK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5QNW6-1", "protein_name": "Histone H2B type 2-F", "gene_name": "H2BC18", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93077-1", "protein_name": "Histone H2A type 1-C", "gene_name": "H2AC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KK5-1", "protein_name": "Histone H2A type 1-H", "gene_name": "H2AC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75376-1", "protein_name": "Nuclear receptor corepressor 1", "gene_name": "NCOR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43237-1", "protein_name": "Cytoplasmic dynein 1 light intermediate chain 2", "gene_name": "DYNC1LI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14204-1", "protein_name": "Cytoplasmic dynein 1 heavy chain 1", "gene_name": "DYNC1H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04908-1", "protein_name": "Histone H2A type 1-B/E", "gene_name": "H2AC4; H2AC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20671-1", "protein_name": "Histone H2A type 1-D", "gene_name": "H2AC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16777-1", "protein_name": "Histone H2A type 2-C", "gene_name": "H2AC20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6FI13-1", "protein_name": "Histone H2A type 2-A", "gene_name": "H2AC18; H2AC19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L7L0-1", "protein_name": "Histone H2A type 3", "gene_name": "H2AC25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUE6-1", "protein_name": "Histone H2A type 2-B", "gene_name": "H2AC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96QV6-1", "protein_name": "Histone H2A type 1-A", "gene_name": "H2AC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99878-1", "protein_name": "Histone H2A type 1-J", "gene_name": "H2AC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "A6NHL2-1", "protein_name": "Tubulin alpha chain-like 3", "gene_name": "TUBAL3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NY65-1", "protein_name": "Tubulin alpha-8 chain", "gene_name": "TUBA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DPH7-1", "protein_name": "Tubulin alpha-3C chain", "gene_name": "TUBA3C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00533-1", "protein_name": "Epidermal growth factor receptor", "gene_name": "EGFR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27501258", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 100 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Viral gene products actively promote latent infection by epigenetic silencing mechanisms.", "journal": "Current opinion in virology", "date": "2017", "authors": "Knipe DM, Raja P, Lee J", "reference": { "type": "PubMed", "id": "28415052", "url": "https://pubmed.ncbi.nlm.nih.gov/28415052" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": 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"protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13509-1", "protein_name": "Tubulin beta-3 chain", "gene_name": "TUBB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BQE3-1", "protein_name": "Tubulin alpha-1C chain", "gene_name": "TUBA1C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68371-1", "protein_name": "Tubulin beta-4B chain", "gene_name": "TUBB4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4B7-1", "protein_name": "Tubulin beta-1 chain", "gene_name": "TUBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H853-1", "protein_name": "Tubulin-like protein alpha-4B", "gene_name": "TUBA4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75376-1", "protein_name": "Nuclear receptor corepressor 1", "gene_name": "NCOR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43237-1", "protein_name": "Cytoplasmic dynein 1 light intermediate chain 2", "gene_name": "DYNC1LI2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14204-1", "protein_name": "Cytoplasmic dynein 1 heavy chain 1", "gene_name": "DYNC1H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04908-1", "protein_name": "Histone H2A type 1-B/E", "gene_name": "H2AC4; H2AC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20671-1", "protein_name": "Histone H2A type 1-D", "gene_name": "H2AC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16777-1", "protein_name": "Histone H2A type 2-C", "gene_name": "H2AC20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6FI13-1", "protein_name": "Histone H2A type 2-A", "gene_name": "H2AC18; H2AC19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7L7L0-1", "protein_name": "Histone H2A type 3", "gene_name": "H2AC25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUE6-1", "protein_name": "Histone H2A type 2-B", "gene_name": "H2AC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96QV6-1", "protein_name": "Histone H2A type 1-A", "gene_name": "H2AC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99878-1", "protein_name": "Histone H2A type 1-J", "gene_name": "H2AC14", 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[], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "O35613-1", "protein_name": "Death domain-associated protein 6", "gene_name": "Daxx", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P25446-1", "protein_name": "Tumor necrosis factor receptor superfamily member 6", "gene_name": "Fas", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9215629", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ 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"gene_name": "DAXX", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9407001", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TAPASIN, DAXX, RGL2, HKE2 and four new genes (BING 1, 3 to 5) form a dense cluster at the centromeric end of the MHC.", "journal": "J. Mol. Biol.", "date": "1998", "authors": "Herberg JA, Beck S, Trowsdale J", "reference": { "type": "PubMed", "id": "9545376", "url": "https://pubmed.ncbi.nlm.nih.gov/9545376" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15211-1", "protein_name": "Ral guanine nucleotide dissociation stimulator-like 2", "gene_name": "RGL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15533-1", "protein_name": "Tapasin", "gene_name": "TAPBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15209-1", "protein_name": "Zinc finger and BTB domain-containing protein 22", "gene_name": "ZBTB22", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15212-1", "protein_name": "Prefoldin subunit 6", "gene_name": "PFDN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15213-1", "protein_name": "WD repeat-containing protein 46", "gene_name": "WDR46", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9545376", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death.", "journal": "J. Cell Sci.", "date": "1998", "authors": "Pluta A F, Earnshaw W C, Goldberg I G", "reference": { "type": "PubMed", "id": "9645950", "url": "https://pubmed.ncbi.nlm.nih.gov/9645950" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03188-1", "protein_name": "Centromere protein C", "gene_name": "CENPC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UER7", "url": "https://www.uniprot.org/uniprotkb/Q9UER7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9645950", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Methylation of H3-lysine 79 is mediated by a new family of HMTases without a SET domain.", "journal": "Current biology : CB", "date": "2002", "authors": "Feng Q, Wang H, Ng HH, Erdjument-Bromage H, Tempst P, Struhl K, Zhang Y", "reference": { "type": "PubMed", "id": "12123582", "url": "https://pubmed.ncbi.nlm.nih.gov/12123582" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine 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N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 163, "end_pos": 165, "sequence_org": "GSG", "sequence_mut": "RCR", "comment": "Abolishes methyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" }, { "database": "PubMed", "id": "12123582", "url": "https://pubmed.ncbi.nlm.nih.gov/12123582" } ], "uniprot_canonical_ac": "Q8TEK3-2" } ], "record_id": "pubmed.12123582", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "G9a histone methyltransferase plays a dominant role in euchromatic histone H3 lysine 9 methylation and is essential for early embryogenesis.", "journal": "Genes & development", "date": "2002", "authors": "Tachibana M, Sugimoto K, Nozaki M, Ueda J, Ohta T, Ohki M, Fukuda M, Takeda N, Niida H, Kato H, Shinkai Y", "reference": { "type": "PubMed", "id": "12130538", "url": "https://pubmed.ncbi.nlm.nih.gov/12130538" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Z148-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "Ehmt2", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1165, "end_pos": 1168, "sequence_org": "NHLC", "sequence_mut": "", "comment": "Abolishes histone methyltransferase activity and subsequent repression. In GM3; does not form heterodimer with EHMT1 and is defective in mediating both H3K9me and DNA methylation.", "evidence": [ { "database": "UniProtKB", "id": "Q9Z148", "url": "https://www.uniprot.org/uniprotkb/Q9Z148" }, { "database": "PubMed", "id": "12130538", "url": "https://pubmed.ncbi.nlm.nih.gov/12130538" }, { "database": "PubMed", "id": "18818694", "url": "https://pubmed.ncbi.nlm.nih.gov/18818694" } ], "uniprot_canonical_ac": "Q9Z148-1" } ], "record_id": "pubmed.12130538", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 47 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MLL targets SET domain methyltransferase activity to Hox gene promoters.", "journal": "Molecular cell", "date": "2002", "authors": "Milne TA, Briggs SD, Brock HW, Martin ME, Gibbs D, Allis CD, Hess JL", "reference": { "type": "PubMed", "id": "12453418", "url": "https://pubmed.ncbi.nlm.nih.gov/12453418" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.12453418", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structure and catalytic mechanism of the human histone methyltransferase SET7/9.", "journal": "Nature", "date": "2003", "authors": "Xiao B, Jing C, Wilson JR, Walker PA, Vasisht N, Kelly G, Howell S, Taylor IA, Blackburn GM, Gamblin SJ", "reference": { "type": "PubMed", "id": "12540855", "url": "https://pubmed.ncbi.nlm.nih.gov/12540855" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 245, "end_pos": 245, "sequence_org": "Y", "sequence_mut": "A", "comment": "Significantly reduces the monomethyltransferase activity but increases the dimethyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8WTS6", "url": "https://www.uniprot.org/uniprotkb/Q8WTS6" }, { "database": "PubMed", "id": "12540855", "url": "https://pubmed.ncbi.nlm.nih.gov/12540855" }, { "database": "PubMed", "id": "16433545", "url": "https://pubmed.ncbi.nlm.nih.gov/16433545" } ], "uniprot_canonical_ac": 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9CWR2-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "Smyd3", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42694-1", "protein_name": "ATP-dependent RNA helicase with zinc finger domain", "gene_name": "HELZ", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15235609", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 49 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15851025", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SET8 recognizes the sequence RHRK20VLRDN within the N terminus of histone H4 and mono-methylates lysine 20.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Yin Y, Liu C, Tsai SN, Zhou B, Ngai SM, Zhu G", "reference": { "type": "PubMed", "id": "15964846", "url": "https://pubmed.ncbi.nlm.nih.gov/15964846" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15964846", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "MLL associates specifically with a subset of transcriptionally active target genes.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2005", "authors": "Milne TA, Dou Y, Martin ME, Brock HW, Roeder RG, Hess JL", "reference": { "type": "PubMed", "id": "16199523", "url": "https://pubmed.ncbi.nlm.nih.gov/16199523" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16199523", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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[] } ] }, { "title": "A histone H3 methyltransferase controls epigenetic events required for meiotic prophase.", "journal": "Nature", "date": "2005", "authors": "Hayashi K, Yoshida K, Matsui Y", "reference": { "type": "PubMed", "id": "16292313", "url": "https://pubmed.ncbi.nlm.nih.gov/16292313" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine 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"gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"protein_name": "Breast cancer type 2 susceptibility protein", "gene_name": "BRCA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14565-1", "protein_name": "Meiotic recombination protein DMC1 homolog", "gene_name": "DMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PIW4-1", "protein_name": "Fidgetin-like protein 1", "gene_name": "FIGNL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71UI9-1", "protein_name": "Histone H2A.V", "gene_name": "H2AZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04908-1", "protein_name": "Histone H2A type 1-B/E", "gene_name": "H2AC4; H2AC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20671-1", "protein_name": "Histone H2A type 1-D", "gene_name": "H2AC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16777-1", "protein_name": "Histone H2A type 2-C", "gene_name": "H2AC20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6FI13-1", "protein_name": "Histone H2A type 2-A", "gene_name": "H2AC18; H2AC19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99878-1", "protein_name": "Histone H2A type 1-J", "gene_name": "H2AC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", 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"name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 276, "end_pos": 276, "sequence_org": "Y", "sequence_mut": "F", "comment": "Abolishes histone-lysine N-methyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q96EQ9", "url": "https://www.uniprot.org/uniprotkb/Q96EQ9" }, { "database": "PubMed", "id": "16292313", "url": "https://pubmed.ncbi.nlm.nih.gov/16292313" }, { "database": "PubMed", "id": "24095733", "url": "https://pubmed.ncbi.nlm.nih.gov/24095733" } ], "uniprot_canonical_ac": "Q96EQ9-1" }, { "start_pos": 278, "end_pos": 278, "sequence_org": "G", "sequence_mut": "A", "comment": "Abolishes histone-lysine N-methyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q96EQ9", "url": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis.", "journal": "Biochemistry", "date": "2006", "authors": "Chin HG, Patnaik D, Esteve PO, Jacobsen SE, Pradhan S", "reference": { "type": "PubMed", "id": "16519522", "url": "https://pubmed.ncbi.nlm.nih.gov/16519522" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 64, "end_pos": 64, "sequence_org": "W", "sequence_mut": "A", "comment": "Abolishes methyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "O43463", "url": "https://www.uniprot.org/uniprotkb/O43463" }, { "database": "PubMed", "id": "16519522", "url": "https://pubmed.ncbi.nlm.nih.gov/16519522" } ], "uniprot_canonical_ac": "O43463-1" }, { "start_pos": 67, "end_pos": 67, "sequence_org": "Y", "sequence_mut": "A", "comment": "Abolishes methyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "O43463", "url": "https://www.uniprot.org/uniprotkb/O43463" }, { "database": "PubMed", "id": "16519522", "url": "https://pubmed.ncbi.nlm.nih.gov/16519522" } ], "uniprot_canonical_ac": "O43463-1" } ], 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Characterization of a novel WHSC1-associated SET domain protein with H3K4 and H3K27 methyltransferase activity.", "journal": "Biochemical and biophysical research communications", "date": "2006", "authors": "Kim SM, Kee HJ, Eom GH, Choe NW, Kim JY, Kim YS, Kim SK, Kook H, Kook H, Seo SB", "reference": { "type": "PubMed", "id": "16682010", "url": "https://pubmed.ncbi.nlm.nih.gov/16682010" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16682010", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Coactivator as a target gene specificity determinant for histone H3 lysine 4 methyltransferases.", "journal": "Proceedings of the National Academy of Sciences of the United States of America", "date": "2006", "authors": "Lee S, Lee DK, Dou Y, Lee J, Lee B, Kwak E, Kong YY, Lee SK, Roeder RG, Lee JW", "reference": { "type": "PubMed", "id": "17021013", "url": "https://pubmed.ncbi.nlm.nih.gov/17021013" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14686-1", "protein_name": "Nuclear receptor coactivator 6", "gene_name": "NCOA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17021013", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 47 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Trithorax-group protein ASH1 methylates histone H3 lysine 36.", "journal": "Gene", "date": "2007", "authors": "Tanaka Y, Katagiri Z, Kawahashi K, Kioussis D, Kitajima S", "reference": { "type": "PubMed", "id": "17544230", "url": "https://pubmed.ncbi.nlm.nih.gov/17544230" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99MY8-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "Ash1l", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17544230", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 47 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.", "journal": "Molecular cell", "date": "2007", "authors": "Demers C, Chaturvedi CP, Ranish JA, Juban G, Lai P, Morle F, Aebersold R, Dilworth FJ, Groudine M, Brand M", "reference": { "type": "PubMed", "id": "17707229", "url": "https://pubmed.ncbi.nlm.nih.gov/17707229" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07279-1", "protein_name": "Transcription factor NF-E2 45 kDa subunit", "gene_name": "Nfe2", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17707229", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 47 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Multiple-myeloma-related WHSC1/MMSET isoform RE-IIBP is a histone methyltransferase with transcriptional repression activity.", "journal": "Molecular and cellular biology", "date": "2008", "authors": "Kim JY, Kee HJ, Choe NW, Kim SM, Eom GH, Baek HJ, Kook H, Kook H, Seo SB", "reference": { "type": "PubMed", "id": "18172012", "url": "https://pubmed.ncbi.nlm.nih.gov/18172012" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8BVE8-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "Nsd2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1138, "end_pos": 1138, "sequence_org": "R", "sequence_mut": "A", "comment": "No methyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8BVE8", "url": "https://www.uniprot.org/uniprotkb/Q8BVE8" }, { "database": "PubMed", "id": "18172012", "url": "https://pubmed.ncbi.nlm.nih.gov/18172012" } ], "uniprot_canonical_ac": "Q8BVE8-1" }, { "start_pos": 1144, "end_pos": 1144, "sequence_org": "C", "sequence_mut": "A", "comment": "No methyltransferase activity.", "evidence": [ { "database": "UniProtKB", "id": "Q8BVE8", "url": "https://www.uniprot.org/uniprotkb/Q8BVE8" }, { "database": "PubMed", "id": "18172012", "url": "https://pubmed.ncbi.nlm.nih.gov/18172012" } ], "uniprot_canonical_ac": "Q8BVE8-1" } ], "record_id": "pubmed.18172012", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 47 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The target of the NSD family of histone lysine methyltransferases depends on the nature of the substrate.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Li Y, Trojer P, Xu CF, Cheung P, Kuo A, Drury WJ 3rd, Qiao Q, Neubert TA, Xu RM, Gozani O, Reinberg D", "reference": { "type": "PubMed", "id": "19808676", "url": "https://pubmed.ncbi.nlm.nih.gov/19808676" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19808676", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The structure of NSD1 reveals an autoregulatory mechanism underlying histone H3K36 methylation.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Qiao Q, Li Y, Chen Z, Wang M, Reinberg D, Xu RM", "reference": { "type": "PubMed", "id": "21196496", "url": "https://pubmed.ncbi.nlm.nih.gov/21196496" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1914, "end_pos": 1914, "sequence_org": "R", "sequence_mut": "C", "comment": "Reduced enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "Q96L73", "url": "https://www.uniprot.org/uniprotkb/Q96L73" }, { "database": "PubMed", "id": "21196496", "url": "https://pubmed.ncbi.nlm.nih.gov/21196496" } ], "uniprot_canonical_ac": "Q96L73-1" }, { "start_pos": 1952, "end_pos": 1952, "sequence_org": "R", "sequence_mut": "W", "comment": "Nearly abolished enzyme activity.", "evidence": [ { "database": "UniProtKB", "id": "Q96L73", "url": "https://www.uniprot.org/uniprotkb/Q96L73" }, { "database": "PubMed", "id": "21196496", "url": "https://pubmed.ncbi.nlm.nih.gov/21196496" } ], "uniprot_canonical_ac": "Q96L73-1" } ], "record_id": "pubmed.21196496", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural and functional profiling of the human histone methyltransferase SMYD3.", "journal": "PloS one", "date": "2011", "authors": "Foreman KW, Brown M, Park F, Emtage S, Harriss J, Das C, Zhu L, Crew A, Arnold L, Shaaban S, Tucker P", "reference": { "type": "PubMed", "id": "21779408", "url": "https://pubmed.ncbi.nlm.nih.gov/21779408" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21779408", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 46 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Histone methyltransferase SETD3 regulates muscle differentiation.", "journal": "The Journal of biological chemistry", "date": "2011", "authors": "Eom GH, Kim KB, Kim JH, Kim JY, Kim JR, Kee HJ, Kim DW, Choe N, Park HJ, Son HJ, Choi SY, Kook H, Seo SB", "reference": { "type": "PubMed", "id": "21832073", "url": "https://pubmed.ncbi.nlm.nih.gov/21832073" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6VMQ6-1", "protein_name": "Activating transcription factor 7-interacting protein 1", "gene_name": "ATF7IP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR48-1", "protein_name": "Histone-lysine N-methyltransferase ASH1L", "gene_name": "ASH1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43463-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H1", "gene_name": "SUV39H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09028-1", "protein_name": "Histone-binding protein RBBP4", "gene_name": "RBBP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBL3-1", "protein_name": "Set1/Ash2 histone methyltransferase complex subunit ASH2", "gene_name": "ASH2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C005-1", "protein_name": "Protein dpy-30 homolog", "gene_name": "DPY30", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61964-1", "protein_name": "WD repeat-containing protein 5", "gene_name": "WDR5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "P68431-1", "protein_name": "Histone H3.1", "gene_name": "H3C10; H3C11; H3C12; H3C1; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14686-1", "protein_name": "Histone-lysine N-methyltransferase 2D", "gene_name": "KMT2D", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q03164-1", "protein_name": "Histone-lysine N-methyltransferase 2A", "gene_name": "KMT2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96T68-1", "protein_name": "Histone-lysine N-methyltransferase SETDB2", "gene_name": "SETDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10085-1", "protein_name": "Myoblast determination protein 1", "gene_name": "Myod1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q91WC0-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "Setd3", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q03112-7", "protein_name": "Histone-lysine N-methyltransferase MECOM", "gene_name": "MECOM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71DI3-1", "protein_name": "Histone H3.2", "gene_name": "H3C13; H3C14; H3C15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H9B1-1", "protein_name": "Histone-lysine N-methyltransferase EHMT1", "gene_name": "EHMT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQR1-1", "protein_name": "N-lysine methyltransferase KMT5A", "gene_name": "KMT5A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q4FZB7-1", "protein_name": "Histone-lysine N-methyltransferase KMT5B", "gene_name": "KMT5B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG4-1", "protein_name": "N-lysine methyltransferase SMYD2", "gene_name": "SMYD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQV7-1", "protein_name": "Histone-lysine N-methyltransferase PRDM9", "gene_name": "PRDM9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYW2-1", "protein_name": "Histone-lysine N-methyltransferase SETD2", "gene_name": "SETD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86Y97-1", "protein_name": "Histone-lysine N-methyltransferase KMT5C", "gene_name": "KMT5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WTS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD7", "gene_name": "SETD7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "G3V6U9-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "Setd3", "tax_name": "Rat" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.21832073", "abstract": "", "glycosylation": 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"count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming.", "journal": "Molecular cell", "date": "2011", "authors": "Kuo AJ, Cheung P, Chen K, Zee BM, Kioi M, Lauring J, Xi Y, Park BH, Shi X, Garcia BA, Li W, Gozani O", "reference": { "type": "PubMed", "id": "22099308", "url": "https://pubmed.ncbi.nlm.nih.gov/22099308" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15047-1", "protein_name": "Histone-lysine N-methyltransferase SETDB1", "gene_name": "SETDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZN18-1", "protein_name": "Zinc finger protein AEBP2", "gene_name": "AEBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15047-1", "protein_name": "Histone-lysine N-methyltransferase SETD1A", "gene_name": "SETD1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEZ4-1", "protein_name": "Histone-lysine N-methyltransferase 2C", "gene_name": "KMT2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UMN6-1", "protein_name": "Histone-lysine N-methyltransferase 2B", "gene_name": "KMT2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15291-1", "protein_name": "Retinoblastoma-binding protein 5", "gene_name": "RBBP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96L73-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-36 specific", "gene_name": "NSD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19838-1", "protein_name": "Nuclear factor NF-kappa-B p105 subunit", "gene_name": "NFKB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16576-1", "protein_name": "Histone-binding protein RBBP7", "gene_name": "RBBP7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAZ2-1", "protein_name": "Histone-lysine N-methyltransferase PRDM16", "gene_name": "PRDM16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPS6-1", "protein_name": "Histone-lysine N-methyltransferase SETD1B", "gene_name": "SETD1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TBK2-1", "protein_name": "N-lysine methyltransferase SETD6", "gene_name": "SETD6", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75530-1", "protein_name": "Polycomb protein EED", "gene_name": "EED", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86TU7-1", "protein_name": "Actin-histidine N-methyltransferase", "gene_name": "SETD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H7B4-1", "protein_name": "Histone-lysine N-methyltransferase SMYD3", "gene_name": "SMYD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ95-1", "protein_name": "Histone-lysine N-methyltransferase NSD3", "gene_name": "NSD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H5I1-1", "protein_name": "Histone-lysine N-methyltransferase SUV39H2", "gene_name": "SUV39H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96KQ7-1", "protein_name": "Histone-lysine N-methyltransferase EHMT2", "gene_name": "EHMT2", "tax_name": "Human" }, { "uniprot_canonical_ac": 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Blyth Moira, Banka Siddharth, Afenjar Alexandra, Mignot Cyril, Robin-Renaldo Florence, Keren Boris, Kanca Oguz, Mao Xiao, Wegner Daniel J, Sisco Kathleen, Shinawi Marwan, , Wangler Michael F, Weksberg Rosanna, Yamamoto Shinya, Costain Gregory, Bellen Hugo J", "reference": { "type": "PubMed", "id": "37827158", "url": "https://pubmed.ncbi.nlm.nih.gov/37827158" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TEK3-2", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "DOT1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8INR6-1", "protein_name": "Histone-lysine N-methyltransferase, H3 lysine-79 specific", "gene_name": "gpp", "tax_name": "Fruit fly" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TEK3", "url": "https://www.uniprot.org/uniprotkb/Q8TEK3" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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Julkunen I, Lin R, Hiscott J", "reference": { "type": "PubMed", "id": "11035028", "url": "https://pubmed.ncbi.nlm.nih.gov/11035028" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12956-1", "protein_name": "DNA repair protein Ku70", "gene_name": "XRCC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7RTR2-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "NLRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJV9-1", "protein_name": "Probable ATP-dependent RNA helicase DDX41", "gene_name": "DDX41", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSU2-3", "protein_name": "Three-prime repair exonuclease 1", "gene_name": "TREX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13010-1", "protein_name": "DNA repair protein Ku80", "gene_name": "XRCC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78527-1", "protein_name": "DNA-dependent protein kinase catalytic subunit", "gene_name": "PRKDC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2E6-1", "protein_name": "E3 ubiquitin-protein ligase DTX4", "gene_name": "DTX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11035028", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 13 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "Novel properties of the protein kinase CK2-site-regulated nuclear- localization sequence of the interferon-induced nuclear factor IFI 16.", "journal": "The Biochemical journal", "date": "2001", "authors": "Briggs LJ, Johnstone RW, Elliot RM, Xiao CY, Dawson M, Trapani JA, Jans DA", "reference": { "type": "PubMed", "id": "11115400", "url": "https://pubmed.ncbi.nlm.nih.gov/11115400" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 132, "end_pos": 132, "kinase_uniprot_canonical_ac": "P68400-1", "kinase_gene_name": "CSNK2A1", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q16666", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q16666" }, { "database": "PubMed", "id": "11115400", "url": "https://pubmed.ncbi.nlm.nih.gov/11115400" } ], "site_lbl": "Ser132", "uniprot_canonical_ac": "Q16666-1" } ], "record_id": "pubmed.11115400", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Functional interaction between p53 and the interferon-inducible nucleoprotein IFI 16.", "journal": "Oncogene", "date": "2000-12-07", "authors": "Johnstone R W, Wei W, Greenway A, Trapani J A", "reference": { "type": "PubMed", "id": "11146555", "url": "https://pubmed.ncbi.nlm.nih.gov/11146555" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.11146555", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IKK-i and TBK-1 are enzymatically distinct from the homologous enzyme IKK-2: comparative analysis of recombinant human IKK-i, TBK-1, and IKK-2.", "journal": "The Journal of biological chemistry", "date": "2002", "authors": "Kishore N, Huynh QK, Mathialagan S, Hall T, Rouw S, Creely D, Lange G, Caroll J, Reitz B, Donnelly A, Boddupalli H, Combs RG, Kretzmer K, Tripp CS", "reference": { "type": "PubMed", "id": "11839743", "url": "https://pubmed.ncbi.nlm.nih.gov/11839743" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12956-1", "protein_name": "DNA repair protein Ku70", "gene_name": "XRCC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29466-1", "protein_name": "Caspase-1", "gene_name": "CASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7RTR2-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "NLRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43378-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 9", "gene_name": "PTPN9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJV9-1", "protein_name": "Probable ATP-dependent RNA helicase DDX41", "gene_name": "DDX41", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NZH6-1", "protein_name": "Interleukin-37", "gene_name": "IL37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSU2-3", "protein_name": "Three-prime repair exonuclease 1", "gene_name": "TREX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6IA17-1", "protein_name": "Single Ig IL-1-related receptor", "gene_name": "SIGIRR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q05209-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 12", "gene_name": "PTPN12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H3S7-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 23", "gene_name": "PTPN23", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29074-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 4", "gene_name": "PTPN4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13478-1", "protein_name": "Interleukin-18 receptor 1", "gene_name": "IL18R1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13010-1", "protein_name": "DNA repair protein Ku80", "gene_name": "XRCC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P84022-1", "protein_name": "SMAD family member 3", "gene_name": "SMAD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78527-1", "protein_name": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IKKepsilon and TBK1 are essential components of the IRF3 signaling pathway.", "journal": "Nature immunology", "date": "2003", "authors": "Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T", "reference": { "type": "PubMed", "id": "12692549", "url": "https://pubmed.ncbi.nlm.nih.gov/12692549" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15111-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha", "gene_name": "CHUK", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15750-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1", "gene_name": "TAB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14457-1", "protein_name": "Beclin-1", "gene_name": "BECN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92844-1", "protein_name": "TRAF family member-associated NF-kappa-B activator", "gene_name": "TANK", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43187-1", "protein_name": "Interleukin-1 receptor-associated kinase-like 2", "gene_name": "IRAK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12956-1", "protein_name": "DNA repair protein Ku70", "gene_name": "XRCC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y4K3-1", "protein_name": "TNF receptor-associated factor 6", "gene_name": "TRAF6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7RTR2-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "NLRC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJV9-1", "protein_name": "Probable ATP-dependent RNA helicase DDX41", "gene_name": "DDX41", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62633-1", "protein_name": "CCHC-type zinc finger nucleic acid binding protein", "gene_name": "CNBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11226-1", "protein_name": "Mannose-binding protein C", "gene_name": "MBL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NSU2-3", "protein_name": "Three-prime repair exonuclease 1", "gene_name": "TREX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P30511-1", "protein_name": "HLA class I histocompatibility antigen, alpha chain F", "gene_name": "HLA-F", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13747-1", "protein_name": "HLA class I histocompatibility antigen, alpha chain E", "gene_name": "HLA-E", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17693-1", "protein_name": "HLA class I histocompatibility antigen, alpha chain G", "gene_name": "HLA-G", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01563-1", "protein_name": "Interferon alpha-2", "gene_name": "IFNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01567-1", "protein_name": "Interferon alpha-7", "gene_name": "IFNA7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01568-1", "protein_name": "Interferon alpha-21", "gene_name": "IFNA21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01569-1", "protein_name": "Interferon alpha-5", "gene_name": "IFNA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01570-1", "protein_name": "Interferon alpha-14", "gene_name": "IFNA14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32881-1", "protein_name": "Interferon alpha-8", "gene_name": "IFNA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PD4-1", "protein_name": "Interleukin-17F", "gene_name": "IL17F", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05013-1", "protein_name": "Interferon alpha-6", "gene_name": "IFNA6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99570-1", "protein_name": "Phosphoinositide 3-kinase regulatory subunit 4", "gene_name": "PIK3R4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95487-1", "protein_name": "Protein transport protein Sec24B", "gene_name": "SEC24B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6B6-1", "protein_name": "Small COPII coat GTPase SAR1B", "gene_name": "SAR1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14920-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta", "gene_name": "IKBKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13283-1", "protein_name": "Ras GTPase-activating protein-binding protein 1", "gene_name": "G3BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29350-1", "protein_name": "Tyrosine-protein phosphatase non-receptor type 6", "gene_name": "PTPN6", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62985-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "O60603-1", "protein_name": "Toll-like receptor 2", "gene_name": "TLR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43318-1", "protein_name": "Mitogen-activated protein kinase kinase kinase 7", "gene_name": "MAP3K7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35247-1", "protein_name": "Pulmonary surfactant-associated protein D", "gene_name": "SFTPD", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52630-3", "protein_name": "Signal transducer and activator of transcription 2", "gene_name": "STAT2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48740-1", "protein_name": "Mannan-binding lectin serine protease 1", "gene_name": "MASP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C037-1", "protein_name": "E3 ubiquitin-protein ligase TRIM4", "gene_name": "TRIM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYK1-1", "protein_name": "Toll-like receptor 7", "gene_name": "TLR7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16552-1", "protein_name": "Interleukin-17A", "gene_name": "IL17A", "tax_name": "Human" }, { "uniprot_canonical_ac": "A0A8V0ZHE2-1", "protein_name": "TRAF family member associated NFKB activator", "gene_name": "TANK", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P08238-1", "protein_name": "Heat shock protein HSP 90-beta", "gene_name": "HSP90AB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10321-1", "protein_name": "HLA class I histocompatibility antigen, C alpha chain", "gene_name": "HLA-C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04439-1", "protein_name": "HLA class I histocompatibility antigen, A alpha chain", "gene_name": "HLA-A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92985-1", "protein_name": "Interferon regulatory factor 7", "gene_name": "IRF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC29-1", "protein_name": "Nucleotide-binding oligomerization domain-containing protein 2", "gene_name": "NOD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61769-1", "protein_name": "Beta-2-microglobulin", "gene_name": "B2M", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13010-1", "protein_name": "DNA repair protein Ku80", "gene_name": "XRCC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05014-1", "protein_name": "Interferon alpha-4", "gene_name": "IFNA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52292-1", "protein_name": "Importin subunit alpha-1", "gene_name": "KPNA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07900-1", "protein_name": "Heat shock protein HSP 90-alpha", "gene_name": "HSP90AA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78527-1", "protein_name": "DNA-dependent protein kinase catalytic subunit", "gene_name": "PRKDC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUD6-1", "protein_name": "E3 ubiquitin-protein ligase RNF135", "gene_name": "RNF135", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UN86-1", "protein_name": "Ras GTPase-activating protein-binding protein 2", "gene_name": "G3BP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29597-1", "protein_name": "Non-receptor tyrosine-protein kinase TYK2", "gene_name": "TYK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0DY56-1", "protein_name": "Interferon alpha-1", "gene_name": "IFNA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG62-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "Q8NEB9-1", "protein_name": "Phosphatidylinositol 3-kinase catalytic subunit type 3", "gene_name": "PIK3C3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZNE5-1", "protein_name": "Beclin 1-associated autophagy-related key regulator", "gene_name": "ATG14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N5C8-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3", "gene_name": "TAB3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NYJ8-1", "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2", "gene_name": "TAB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43353-1", "protein_name": "Receptor-interacting serine/threonine-protein kinase 2", "gene_name": "RIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53992-1", "protein_name": "Protein transport protein Sec24C", "gene_name": "SEC24C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3LXA3-1", "protein_name": "Triokinase/FMN cyclase", "gene_name": "TKFC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01566-1", "protein_name": "Interferon alpha-10", "gene_name": "IFNA10", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01571-1", "protein_name": "Interferon alpha-17", "gene_name": "IFNA17", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01574-1", "protein_name": "Interferon beta", "gene_name": "IFNB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P05015-1", "protein_name": "Interferon alpha-16", "gene_name": "IFNA16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BYX4-1", "protein_name": "Interferon-induced helicase C domain-containing protein 1", "gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15455-1", "protein_name": "Toll-like receptor 3", "gene_name": "TLR3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51617-1", "protein_name": "Interleukin-1 receptor-associated kinase 1", "gene_name": "IRAK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15399-1", "protein_name": "Toll-like receptor 1", "gene_name": "TLR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NR97-1", "protein_name": "Toll-like receptor 8", "gene_name": "TLR8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94826-1", "protein_name": "Mitochondrial import receptor subunit TOM70", "gene_name": "TOMM70", "tax_name": "Human" }, { "uniprot_canonical_ac": "E1C626-1", "protein_name": "TNF receptor-associated factor", "gene_name": "TRAF6", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P79781-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "Q90643-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y239-1", "protein_name": "Nucleotide-binding oligomerization domain-containing protein 1", "gene_name": "NOD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15436-1", "protein_name": "Protein transport protein Sec23A", "gene_name": "SEC23A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08571-1", "protein_name": "Monocyte differentiation antigen CD14", "gene_name": "CD14", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42224-1", "protein_name": "Signal transducer and activator of transcription 1-alpha/beta", "gene_name": "STAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2E6-1", "protein_name": "E3 ubiquitin-protein ligase DTX4", "gene_name": "DTX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94855-1", "protein_name": "Protein transport protein Sec24D", "gene_name": "SEC24D", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95486-1", "protein_name": "Protein transport protein Sec24A", "gene_name": "SEC24A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6PKG0-1", "protein_name": "La-related protein 1", "gene_name": "LARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NAC3-1", "protein_name": "Interleukin-17 receptor C", "gene_name": "IL17RC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13404-4", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 1", "gene_name": "UBE2V1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96F46-1", "protein_name": "Interleukin-17 receptor A", "gene_name": "IL17RA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01893-1", "protein_name": "Putative HLA class I histocompatibility antigen, alpha chain H", "gene_name": "HLA-H", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H171-1", "protein_name": "Z-DNA-binding protein 1", "gene_name": "ZBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86XR7-1", "protein_name": "TIR domain-containing adapter molecule 2", "gene_name": "TICAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Role of IFI 16, a member of the interferon-inducible p200-protein family, in prostate epithelial cellular senescence.", "journal": "Oncogene", "date": "2003-07-31", "authors": "Xin Hong, Curry Jonathan, Johnstone Ricky W, Nickoloff Brian J, Choubey Divaker", "reference": { "type": "PubMed", "id": "12894224", "url": "https://pubmed.ncbi.nlm.nih.gov/12894224" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", 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"date": "1992", "authors": "Trapani J A, Browne K A, Dawson M J, Ramsay R G, Eddy R L, Show T B, White P C, Dupont B", "reference": { "type": "PubMed", "id": "1526658", "url": "https://pubmed.ncbi.nlm.nih.gov/1526658" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1526658", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", 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"protein_name": "Three-prime repair exonuclease 1", "gene_name": "TREX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C037-1", "protein_name": "E3 ubiquitin-protein ligase TRIM4", "gene_name": "TRIM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92985-1", "protein_name": "Interferon regulatory factor 7", "gene_name": "IRF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial 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"gene_name": "IFIH1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13114-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "TRAF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2E6-1", "protein_name": "E3 ubiquitin-protein ligase DTX4", "gene_name": "DTX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16281057", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 26 } ], "sort_fields": [ 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response.", "journal": "Nature", "date": "2006", "authors": "Oganesyan G, Saha SK, Guo B, He JQ, Shahangian A, Zarnegar B, Perry A, Cheng G", "reference": { "type": "PubMed", "id": "16306936", "url": "https://pubmed.ncbi.nlm.nih.gov/16306936" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", 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"STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJV9-1", "protein_name": "Probable ATP-dependent RNA helicase DDX41", "gene_name": "DDX41", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q60803-1", "protein_name": "TNF receptor-associated factor 3", "gene_name": "Traf3", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q80UF7-1", "protein_name": "TIR domain-containing adapter molecule 1", "gene_name": "Ticam1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NSU2-3", "protein_name": "Three-prime repair exonuclease 1", "gene_name": "TREX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14653-1", "protein_name": "Interferon regulatory factor 3", "gene_name": "IRF3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95786-1", "protein_name": "Antiviral innate immune response receptor RIG-I", "gene_name": "DDX58; RIGI", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BRV8-1", "protein_name": "Suppressor of IKBKE 1", "gene_name": "SIKE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00206-1", "protein_name": "Toll-like receptor 4", "gene_name": "TLR4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6Y9-1", "protein_name": "Lymphocyte antigen 96", "gene_name": "LY96", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9C037-1", "protein_name": "E3 ubiquitin-protein ligase TRIM4", "gene_name": "TRIM4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96CV9-1", "protein_name": "Optineurin", "gene_name": "OPTN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92985-1", "protein_name": "Interferon regulatory factor 7", "gene_name": "IRF7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z434-1", "protein_name": "Mitochondrial antiviral-signaling protein", "gene_name": "MAVS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13010-1", "protein_name": "DNA repair protein Ku80", "gene_name": "XRCC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78527-1", "protein_name": "DNA-dependent protein kinase catalytic subunit", "gene_name": "PRKDC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06124-2", "protein_name": "Tyrosine-protein phosphatase non-receptor type 11", "gene_name": "PTPN11", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUD6-1", "protein_name": "E3 ubiquitin-protein ligase RNF135", "gene_name": "RNF135", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P01574-1", "protein_name": "Interferon beta", "gene_name": 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"uniprot_canonical_ac": "Q86XR7-1", "protein_name": "TIR domain-containing adapter molecule 2", "gene_name": "TICAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IUC6-1", "protein_name": "TIR domain-containing adapter molecule 1", "gene_name": "TICAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16306936", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanisms of activation of interferon regulator factor 3: the role of C-terminal domain phosphorylation in IRF-3 dimerization and DNA binding.", "journal": "Nucleic acids research", "date": "2007", "authors": "Dragan AI, Hargreaves 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "In vivo identification of sumoylation sites by a signature tag and cysteine-targeted affinity purification.", "journal": "J. Biol. Chem.", "date": "2010", "authors": "Blomster HA, Imanishi SY, Siimes J, Kastu J, Morrice NA, Eriksson JE, Sistonen L", "reference": { "type": "PubMed", "id": "20388717", "url": "https://pubmed.ncbi.nlm.nih.gov/20388717" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBG0-1", "protein_name": "C-type mannose receptor 2", "gene_name": "MRC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYA6-1", "protein_name": "Cytoskeleton-associated protein 2-like", "gene_name": "CKAP2L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPN6-1", "protein_name": "SR-related and CTD-associated factor 8", "gene_name": "SCAF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UG01-1", "protein_name": "Intraflagellar transport protein 172 homolog", "gene_name": "IFT172", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJV9-1", "protein_name": "Probable ATP-dependent RNA helicase DDX41", "gene_name": "DDX41", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19474-1", "protein_name": "E3 ubiquitin-protein ligase TRIM21", "gene_name": "TRIM21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N884-1", "protein_name": "Cyclic GMP-AMP synthase", "gene_name": "CGAS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20890285", "abstract": "", "glycosylation": [], "mutagenesis": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "STING is a direct innate immune sensor of cyclic di-GMP.", "journal": "Nature", "date": "2011", "authors": "Burdette DL, Monroe KM, Sotelo-Troha K, Iwig JS, Eckert B, Hyodo M, Hayakawa Y, Vance RE", "reference": { "type": "PubMed", "id": "21947006", "url": "https://pubmed.ncbi.nlm.nih.gov/21947006" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WV6-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "STING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UJV9-1", "protein_name": "Probable ATP-dependent RNA helicase DDX41", "gene_name": "DDX41", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q3TBT3-1", "protein_name": "Stimulator of interferon genes protein", "gene_name": "Sting1", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "P19474-1", "protein_name": "E3 ubiquitin-protein ligase TRIM21", "gene_name": "TRIM21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N884-1", "protein_name": "Cyclic GMP-AMP synthase", 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "IFI16 protein mediates the anti-inflammatory actions of the type-I interferons through suppression of activation of caspase-1 by inflammasomes.", "journal": "PloS one", "date": "2011", "authors": "Veeranki Sudhakar, Duan Xin, Panchanathan Ravichandran, Liu Hongzhu, Choubey Divaker", "reference": { "type": "PubMed", "id": "22046441", "url": "https://pubmed.ncbi.nlm.nih.gov/22046441" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14862-1", "protein_name": "Interferon-inducible protein AIM2", "gene_name": "AIM2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": 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"PLoS pathogens", "date": "2012-01", "authors": "Gariano Grazia Rosaria, Dell'Oste Valentina, Bronzini Matteo, Gatti Deborah, Luganini Anna, De Andrea Marco, Gribaudo Giorgio, Gariglio Marisa, Landolfo Santo", "reference": { "type": "PubMed", "id": "22291595", "url": "https://pubmed.ncbi.nlm.nih.gov/22291595" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q16666", "url": "https://www.uniprot.org/uniprotkb/Q16666" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.22291595", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "STING specifies IRF3 phosphorylation by TBK1 in the cytosolic DNA signaling pathway.", "journal": "Science signaling", "date": "2012", "authors": "Tanaka Y, Chen ZJ", "reference": { "type": "PubMed", "id": "22394562", "url": "https://pubmed.ncbi.nlm.nih.gov/22394562" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding.", "journal": "Immunity", "date": "2012", "authors": "Ouyang S, Song X, Wang Y, Ru H, Shaw N, Jiang Y, Niu F, Zhu Y, Qiu W, Parvatiyar K, Li Y, Zhang R, Cheng G, Liu ZJ", "reference": { "type": "PubMed", "id": "22579474", "url": "https://pubmed.ncbi.nlm.nih.gov/22579474" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q16666-1", "protein_name": "Gamma-interferon-inducible protein 16", "gene_name": "IFI16", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHD2-1", "protein_name": "Serine/threonine-protein kinase TBK1", "gene_name": "TBK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12956-1", "protein_name": "DNA repair protein Ku70", "gene_name": "XRCC6", "tax_name": "Human" }, { 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] } ]