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Virol.", "date": "2005", "authors": "Viejo-Borbolla Abel, Ottinger Matthias, Br\u00fcning Eva, B\u00fcrger Antje, K\u00f6nig Regina, Kati Emrah, Sheldon Julie A, Schulz Thomas F", "reference": { "type": "PubMed", "id": "16227282", "url": "https://pubmed.ncbi.nlm.nih.gov/16227282" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P25440-1", "protein_name": "Bromodomain-containing protein 2", "gene_name": "BRD2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P25440", "url": "https://www.uniprot.org/uniprotkb/P25440" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16227282", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CtIP mutations cause Seckel and Jawad syndromes.", "journal": "PLoS Genet.", "date": "2011", "authors": "Qvist Per, Huertas Pablo, Jimeno Sonia, Nyegaard Mette, Hassan Muhammad J, Jackson Stephen P, B\u00f8rglum Anders D", "reference": { "type": "PubMed", "id": "21998596", "url": "https://pubmed.ncbi.nlm.nih.gov/21998596" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q99708-1", 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"total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Prolyl isomerase PIN1 regulates DNA double-strand break repair by counteracting DNA end resection.", "journal": "Molecular cell", "date": "2013", "authors": "Steger M, Murina O, Huhn D, Ferretti LP, Walser R, Hanggi K, Lafranchi L, Neugebauer C, Paliwal S, Janscak P, Gerrits B, Del Sal G, Zerbe O, Sartori AA", "reference": { "type": "PubMed", "id": "23623683", "url": "https://pubmed.ncbi.nlm.nih.gov/23623683" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q99708-1", "protein_name": "DNA endonuclease RBBP8", "gene_name": "RBBP8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13526-1", "protein_name": 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Impaired PIN1-binding, partially decreased CUL3/KLHL15-mediated proteasomal degradation, no effect on BRCA1-, MRE11-, nor on KLHL15-binding; when associated with A-276.", "evidence": [ { "database": "UniProtKB", "id": "Q99708", "url": "https://www.uniprot.org/uniprotkb/Q99708" }, { "database": "PubMed", "id": "23623683", "url": "https://pubmed.ncbi.nlm.nih.gov/23623683" }, { "database": "PubMed", "id": "27561354", "url": "https://pubmed.ncbi.nlm.nih.gov/27561354" } ], "uniprot_canonical_ac": "Q99708-1" }, { "start_pos": 113, "end_pos": 113, "sequence_org": "C", "sequence_mut": "A", "comment": "Loss of peptidyl-prolyl cis/trans isomerase activity; decrease in DNA repair of double-strand breaks by homologous recombination slightly less efficient than that observed with wild-type protein. No effect on RBBP8/CtIP.", "evidence": [ { "database": "UniProtKB", "id": "Q13526", "url": "https://www.uniprot.org/uniprotkb/Q13526" }, { "database": "PubMed", "id": "23623683", "url": "https://pubmed.ncbi.nlm.nih.gov/23623683" }, { "database": "PubMed", "id": "26942675", "url": "https://pubmed.ncbi.nlm.nih.gov/26942675" } ], "uniprot_canonical_ac": "Q13526-1" }, { "start_pos": 34, "end_pos": 34, "sequence_org": "W", "sequence_mut": "A", "comment": "Loss of binding to phosphorylated target proteins, including to phosphorylated RBBP8/CtIP; decrease in DNA repair of double-strand breaks by homologous recombination less efficient than that observed with wild-type protein. Abolishes interaction with IRAK3/IRAK-M. 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "CtIP is required for DNA damage-dependent induction of P21.", "journal": "Cell cycle (Georgetown, Tex.)", "date": "2014", "authors": "Liu B, Cong 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"date": "1999", "authors": "Jordan-Sciutto KL, Dragich JM, Bowser R", "reference": { "type": "PubMed", "id": "10403843", "url": "https://pubmed.ncbi.nlm.nih.gov/10403843" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q12830-1", "protein_name": "Nucleosome-remodeling factor subunit BPTF", "gene_name": "BPTF", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q12830", "url": "https://www.uniprot.org/uniprotkb/Q12830" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10403843", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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