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"title": "The X-ray Crystallographic Structure of Human EAT2 (SH2D1B).", "journal": "Protein and peptide letters", "date": "2016", "authors": "Taha M, Nezerwa E, Nam HJ", "reference": { "type": "PubMed", "id": "27586300", "url": "https://pubmed.ncbi.nlm.nih.gov/27586300" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O14796-1", "protein_name": "SH2 domain-containing protein 1B", "gene_name": "SH2D1B", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O14796", "url": "https://www.uniprot.org/uniprotkb/O14796" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.27586300", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ 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Virol.", "date": "1999", "authors": "Bieniasz PD, Grdina TA, Bogerd HP, Cullen BR", "reference": { "type": "PubMed", "id": "10364329", "url": "https://pubmed.ncbi.nlm.nih.gov/10364329" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "O60563-1", "protein_name": "Cyclin-T1", "gene_name": "CCNT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60583-1", "protein_name": "Cyclin-T2", "gene_name": "CCNT2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "O60563", "url": "https://www.uniprot.org/uniprotkb/O60563" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 260, "end_pos": 260, "sequence_org": "N", "sequence_mut": "C", "comment": "Activation of HIV-1 Tat function.", "evidence": [ { "database": "UniProtKB", "id": "O60583", "url": "https://www.uniprot.org/uniprotkb/O60583" }, { "database": "PubMed", "id": "10364329", "url": "https://pubmed.ncbi.nlm.nih.gov/10364329" } ], "uniprot_canonical_ac": "O60583-1" } ], "record_id": "pubmed.10364329", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Relief of two built-In autoinhibitory mechanisms in P-TEFb is required for assembly of a multicomponent transcription elongation complex at the human immunodeficiency virus type 1 promoter.", "journal": "Mol. 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Very Early Endosomes via Opposing APPL1 Mechanisms.", "journal": "Cell reports", "date": "2017", "authors": "Sposini S, Jean-Alphonse FG, Ayoub MA, Oqua A, West C, Lavery S, Brosens JJ, Reiter E, Hanyaloglu AC", "reference": { "type": "PubMed", "id": "29212031", "url": "https://pubmed.ncbi.nlm.nih.gov/29212031" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UKG1-1", "protein_name": "DCC-interacting protein 13-alpha", "gene_name": "APPL1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UKG1", "url": "https://www.uniprot.org/uniprotkb/Q9UKG1" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 410, "end_pos": 410, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by PKA", "evidence": [ { "database": "UniProtKB", "id": "Q9UKG1", "url": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Dysfunctional APPL1-Mediated Epigenetic Regulation in Diabetic Vascular Injury.", "journal": "Arteriosclerosis, thrombosis, and vascular biology", "date": "2023-12", "authors": "Du Yunhui, Duan Yanru, Zhao Jianli, Liu Caihong, Zhang Zhen, Zhang John, Meng Zhijun, Wang Xiaoliang, Lau Wayne Bond, Xie Dina, Lopez Bernard L, Christopher Theodore A, Gao Erhe, Koch Walter W, Liu Huirong, Liu Demin, Ma Xin-Liang, Gu Guoqiang, Wang Yajing", "reference": { "type": "PubMed", "id": "37795615", "url": "https://pubmed.ncbi.nlm.nih.gov/37795615" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9UKG1-1", "protein_name": "DCC-interacting protein 13-alpha", "gene_name": "APPL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8K3H0-1", "protein_name": "DCC-interacting protein 13-alpha", "gene_name": "Appl1", "tax_name": "Mouse" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9UKG1", 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Substrate recognition by the Lyn protein-tyrosine kinase. NMR structure of the immunoreceptor tyrosine-based activation motif signaling region of the B cell antigen receptor.", "journal": "The Journal of biological chemistry", "date": "2000", "authors": "Gaul BS, Harrison ML, Geahlen RL, Burton RA, Post CB", "reference": { "type": "PubMed", "id": "10748115", "url": "https://pubmed.ncbi.nlm.nih.gov/10748115" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P07948-1", "protein_name": "Tyrosine-protein kinase Lyn", "gene_name": "LYN", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11912-1", "protein_name": "B-cell antigen receptor complex-associated protein alpha chain", "gene_name": "CD79A", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P07948", "url": "https://www.uniprot.org/uniprotkb/P07948" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.10748115", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"Genetic and clinical characteristics of ZNF408-related familial exudative vitreoretinopathy.", "journal": "The Journal of international medical research", "date": "2023-09", "authors": "Tao Xueying, He Liying, Cen Chao, Liu Ya, Li Qi, Gong Liyan, Zhou Wenke, Li Chunmei", "reference": { "type": "PubMed", "id": "37684015", "url": "https://pubmed.ncbi.nlm.nih.gov/37684015" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H9D4-1", "protein_name": "Zinc finger protein 408", "gene_name": "ZNF408", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H9D4", "url": "https://www.uniprot.org/uniprotkb/Q9H9D4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.37684015", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Triallelic inheritance in Bardet-Biedl syndrome, a Mendelian recessive disorder.", "journal": "Science (New York, N.Y.)", "date": "2001", "authors": "Katsanis N, Ansley SJ, Badano JL, Eichers ER, Lewis RA, Hoskins BE, Scambler PJ, Davidson WS, Beales PL, Lupski JR", "reference": { "type": "PubMed", "id": "11567139", "url": "https://pubmed.ncbi.nlm.nih.gov/11567139" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BXC9-1", "protein_name": "BBSome complex member BBS2", "gene_name": "BBS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NPJ1-1", "protein_name": "Molecular chaperone MKKS", "gene_name": "MKKS", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BXC9", "url": "https://www.uniprot.org/uniprotkb/Q9BXC9" } ], "common_name": "Human", "glygen_name": "Human", 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triallelism.", "journal": "European journal of human genetics : EJHG", "date": "2006", "authors": "Laurier V, Stoetzel C, Muller J, Thibault C, Corbani S, Jalkh N, Salem N, Chouery E, Poch O, Licaire S, Danse JM, Amati-Bonneau P, Bonneau D, Megarbane A, Mandel JL, Dollfus H", "reference": { "type": "PubMed", "id": "16823392", "url": "https://pubmed.ncbi.nlm.nih.gov/16823392" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BXC9-1", "protein_name": "BBSome complex member BBS2", "gene_name": "BBS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TAM1-1", "protein_name": "BBSome complex assembly protein BBS10", "gene_name": "BBS10", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BXC9", "url": "https://www.uniprot.org/uniprotkb/Q9BXC9" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16823392", 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CF, Ben-Yosef T, Blumenfeld A, Jalas C, Banin E, Sharon D", "reference": { "type": "PubMed", "id": "25541840", "url": "https://pubmed.ncbi.nlm.nih.gov/25541840" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9BXC9-1", "protein_name": "BBSome complex member BBS2", "gene_name": "BBS2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9BXC9", "url": "https://www.uniprot.org/uniprotkb/Q9BXC9" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.25541840", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { 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