[
    {
        "title": "Multiple Ser/Thr-rich degrons mediate the degradation of Ci/Gli by the Cul3-HIB/SPOP E3 ubiquitin ligase.",
        "journal": "Proceedings of the National Academy of Sciences of the United States of America",
        "date": "2009",
        "authors": "Zhang Q, Shi Q, Chen Y, Yue T, Li S, Wang B, Jiang J",
        "reference": {
            "type": "PubMed",
            "id": "19955409",
            "url": "https://pubmed.ncbi.nlm.nih.gov/19955409"
        },
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        ],
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                "name": "Homo sapiens",
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    {
        "title": "A mutation in the second nucleotide binding fold of the cystic fibrosis gene.",
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    {
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        "authors": "Tay SY, Yu X, Wong KN, Panse P, Ng CP, Roy S",
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        "title": "Proteases in MHC class I presentation and cross-presentation.",
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        "authors": "Rock KL, Farfan-Arribas DJ, Shen L",
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    {
        "title": "USP10 regulates p53 localization and stability by deubiquitinating p53.",
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        "authors": "Yuan J, Luo K, Zhang L, Cheville JC, Lou Z",
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                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y256-1",
                "protein_name": "CAAX prenyl protease 2",
                "gene_name": "RCE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NTX7-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF146",
                "gene_name": "RNF146",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95760-1",
                "protein_name": "Interleukin-33",
                "gene_name": "IL33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04908-1",
                "protein_name": "Histone H2A type 1-B/E",
                "gene_name": "H2AC4; H2AC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06899-1",
                "protein_name": "Histone H2B type 1-J",
                "gene_name": "H2BC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20671-1",
                "protein_name": "Histone H2A type 1-D",
                "gene_name": "H2AC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16777-1",
                "protein_name": "Histone H2A type 2-C",
                "gene_name": "H2AC20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6FI13-1",
                "protein_name": "Histone H2A type 2-A",
                "gene_name": "H2AC18; H2AC19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L7L0-1",
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    {
        "title": "Src kinase phosphorylates RUNX3 at tyrosine residues and localizes the protein in the cytoplasm.",
        "journal": "The Journal of biological chemistry",
        "date": "2010",
        "authors": "Goh YM, Cinghu S, Hong ET, Lee YS, Kim JH, Jang JW, Li YH, Chi XZ, Lee KS, Wee H, Ito Y, Oh BC, Bae SC",
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        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.20154143",
        "abstract": "",
        "glycosylation": [],
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    {
        "title": "Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.",
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                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93009-1",
                "protein_name": "Ubiquitin C-terminal hydrolase 7",
                "gene_name": "USP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2K6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 20",
                "gene_name": "USP20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14318-1",
                "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP8",
                "gene_name": "FKBP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78396-1",
                "protein_name": "Cyclin-A1",
                "gene_name": "CCNA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43303-1",
                "protein_name": "Centriolar coiled-coil protein of 110 kDa",
                "gene_name": "CCP110",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14735-1",
                "protein_name": "Insulin-degrading enzyme",
                "gene_name": "IDE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7M764-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein E",
                "gene_name": "Usp17le",
                "tax_name": "Mouse"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
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    {
        "title": "The IKK complex, a central regulator of NF-kappaB activation.",
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                "gene_name": "SEM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16539-1",
                "protein_name": "Mitogen-activated protein kinase 14",
                "gene_name": "MAPK14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00231-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 11",
                "gene_name": "PSMD11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16186-1",
                "protein_name": "Proteasomal ubiquitin receptor ADRM1",
                "gene_name": "ADRM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95999-1",
                "protein_name": "B-cell lymphoma/leukemia 10",
                "gene_name": "BCL10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15111-1",
                "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit alpha",
                "gene_name": "CHUK",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15750-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1",
                "gene_name": "TAB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25963-1",
                "protein_name": "NF-kappa-B inhibitor alpha",
                "gene_name": "NFKBIA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55211-1",
                "protein_name": "Caspase-9",
                "gene_name": "CASP9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43187-1",
                "protein_name": "Interleukin-1 receptor-associated kinase-like 2",
                "gene_name": "IRAK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4K3-1",
                "protein_name": "TNF receptor-associated factor 6",
                "gene_name": "TRAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21580-1",
                "protein_name": "Tumor necrosis factor alpha-induced protein 3",
                "gene_name": "TNFAIP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P29466-1",
                "protein_name": "Caspase-1",
                "gene_name": "CASP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13616-1",
                "protein_name": "Cullin-1",
                "gene_name": "CUL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43405-1",
                "protein_name": "Tyrosine-protein kinase SYK",
                "gene_name": "SYK",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P19838-1",
                "protein_name": "Nuclear factor NF-kappa-B p105 subunit",
                "gene_name": "NFKB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P52564-1",
                "protein_name": "Dual specificity mitogen-activated protein kinase kinase 6",
                "gene_name": "MAP2K6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q01362-1",
                "protein_name": "High affinity immunoglobulin epsilon receptor subunit beta",
                "gene_name": "MS4A2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30273-1",
                "protein_name": "High affinity immunoglobulin epsilon receptor subunit gamma",
                "gene_name": "FCER1G",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15264-1",
                "protein_name": "Mitogen-activated protein kinase 13",
                "gene_name": "MAPK13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7LDG7-1",
                "protein_name": "RAS guanyl-releasing protein 2",
                "gene_name": "RASGRP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TDF6-1",
                "protein_name": "RAS guanyl-releasing protein 4",
                "gene_name": "RASGRP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01767-1",
                "protein_name": "Immunoglobulin heavy variable 3-53",
                "gene_name": "IGHV3-53",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06331-1",
                "protein_name": "Immunoglobulin heavy variable 4-34",
                "gene_name": "IGHV4-34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01597-1",
                "protein_name": "Immunoglobulin kappa variable 1-39",
                "gene_name": "IGKV1-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06310-1",
                "protein_name": "Immunoglobulin kappa variable 2-30",
                "gene_name": "IGKV2-30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06312-1",
                "protein_name": "Immunoglobulin kappa variable 4-1",
                "gene_name": "IGKV4-1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01614-1",
                "protein_name": "Immunoglobulin kappa variable 2D-40",
                "gene_name": "IGKV2D-40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05655-1",
                "protein_name": "Protein kinase C delta type",
                "gene_name": "PRKCD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0DOY2-1",
                "protein_name": "Immunoglobulin lambda constant 2",
                "gene_name": "IGLC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14920-1",
                "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta",
                "gene_name": "IKBKB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXL7-1",
                "protein_name": "Caspase recruitment domain-containing protein 11",
                "gene_name": "CARD11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UDY8-1",
                "protein_name": "Mucosa-associated lymphoid tissue lymphoma translocation protein 1",
                "gene_name": "MALT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96J02-1",
                "protein_name": "E3 ubiquitin-protein ligase Itchy homolog",
                "gene_name": "ITCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42575-1",
                "protein_name": "Caspase-2",
                "gene_name": "CASP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49662-1",
                "protein_name": "Caspase-4",
                "gene_name": "CASP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04432-1",
                "protein_name": "Immunoglobulin kappa variable 1D-39",
                "gene_name": "IGKV1D-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06315-1",
                "protein_name": "Immunoglobulin kappa variable 5-2",
                "gene_name": "IGKV5-2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01699-1",
                "protein_name": "Immunoglobulin lambda variable 1-44",
                "gene_name": "IGLV1-44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01701-1",
                "protein_name": "Immunoglobulin lambda variable 1-51",
                "gene_name": "IGLV1-51",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01704-1",
                "protein_name": "Immunoglobulin lambda variable 2-14",
                "gene_name": "IGLV2-14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01706-1",
                "protein_name": "Immunoglobulin lambda variable 2-11",
                "gene_name": "IGLV2-11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01709-1",
                "protein_name": "Immunoglobulin lambda variable 2-8",
                "gene_name": "IGLV2-8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01717-1",
                "protein_name": "Immunoglobulin lambda variable 3-25",
                "gene_name": "IGLV3-25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01721-1",
                "protein_name": "Immunoglobulin lambda variable 6-57",
                "gene_name": "IGLV6-57",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01703-1",
                "protein_name": "Immunoglobulin lambda variable 1-40",
                "gene_name": "IGLV1-40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01705-1",
                "protein_name": "Immunoglobulin lambda variable 2-23",
                "gene_name": "IGLV2-23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01715-1",
                "protein_name": "Immunoglobulin lambda variable 3-1",
                "gene_name": "IGLV3-1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01718-1",
                "protein_name": "Immunoglobulin lambda variable 3-27",
                "gene_name": "IGLV3-27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04211-1",
                "protein_name": "Immunoglobulin lambda variable 7-43",
                "gene_name": "IGLV7-43",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P53778-1",
                "protein_name": "Mitogen-activated protein kinase 12",
                "gene_name": "MAPK12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49427-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 R1",
                "gene_name": "CDC34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CF74-1",
                "protein_name": "Immunoglobulin lambda constant 6",
                "gene_name": "IGLC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXN2-1",
                "protein_name": "C-type lectin domain family 7 member A",
                "gene_name": "CLEC7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H257-1",
                "protein_name": "Caspase recruitment domain-containing protein 9",
                "gene_name": "CARD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HC29-1",
                "protein_name": "Nucleotide-binding oligomerization domain-containing protein 2",
                "gene_name": "NOD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07948-1",
                "protein_name": "Tyrosine-protein kinase Lyn",
                "gene_name": "LYN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P16885-1",
                "protein_name": "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2",
                "gene_name": "PLCG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14790-1",
                "protein_name": "Caspase-8",
                "gene_name": "CASP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5C8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 3",
                "gene_name": "TAB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYJ8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2",
                "gene_name": "TAB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q04759-1",
                "protein_name": "Protein kinase C theta type",
                "gene_name": "PRKCQ",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43353-1",
                "protein_name": "Receptor-interacting serine/threonine-protein kinase 2",
                "gene_name": "RIPK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61088-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 N",
                "gene_name": "UBE2N",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01825-1",
                "protein_name": "Immunoglobulin heavy variable 4-59",
                "gene_name": "IGHV4-59",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01817-1",
                "protein_name": "Immunoglobulin heavy variable 2-5",
                "gene_name": "IGHV2-5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01824-1",
                "protein_name": "Immunoglobulin heavy variable 4-39",
                "gene_name": "IGHV4-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23083-1",
                "protein_name": "Immunoglobulin heavy variable 1-2",
                "gene_name": "IGHV1-2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01742-1",
                "protein_name": "Immunoglobulin heavy variable 1-69",
                "gene_name": "IGHV1-69",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01768-1",
                "protein_name": "Immunoglobulin heavy variable 3-30",
                "gene_name": "IGHV3-30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95267-1",
                "protein_name": "RAS guanyl-releasing protein 1",
                "gene_name": "RASGRP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01814-1",
                "protein_name": "Immunoglobulin heavy variable 2-70",
                "gene_name": "IGHV2-70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01772-1",
                "protein_name": "Immunoglobulin heavy variable 3-33",
                "gene_name": "IGHV3-33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01762-1",
                "protein_name": "Immunoglobulin heavy variable 3-11",
                "gene_name": "IGHV3-11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01763-1",
                "protein_name": "Immunoglobulin heavy variable 3-48",
                "gene_name": "IGHV3-48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01764-1",
                "protein_name": "Immunoglobulin heavy variable 3-23",
                "gene_name": "IGHV3-23",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01766-1",
                "protein_name": "Immunoglobulin heavy variable 3-13",
                "gene_name": "IGHV3-13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01780-1",
                "protein_name": "Immunoglobulin heavy variable 3-7",
                "gene_name": "IGHV3-7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01782-1",
                "protein_name": "Immunoglobulin heavy variable 3-9",
                "gene_name": "IGHV3-9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51617-1",
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            "url": "https://pubmed.ncbi.nlm.nih.gov/20368735"
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                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 1",
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                "uniprot_canonical_ac": "Q13546-1",
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                "uniprot_canonical_ac": "P51665-1",
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                "uniprot_canonical_ac": "O95271-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "D6RJB6-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
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                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
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                "tax_name": "Human"
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                "tax_name": "Human"
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                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
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                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
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        "title": "Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway.",
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    {
        "title": "Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB.",
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        "title": "Competition between TRAF2 and TRAF6 regulates NF-kappaB activation in human B lymphocytes.",
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    {
        "title": "Structure of proteasome ubiquitin receptor hRpn13 and its activation by the scaffolding protein hRpn2.",
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    {
        "title": "Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish.",
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        "authors": "Kim HR, Richardson J, van Eeden F, Ingham PW",
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    {
        "title": "The deubiquitinating enzyme USP26 is a regulator of androgen receptor signaling.",
        "journal": "Molecular cancer research : MCR",
        "date": "2010",
        "authors": "Dirac AM, Bernards R",
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                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y256-1",
                "protein_name": "CAAX prenyl protease 2",
                "gene_name": "RCE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NTX7-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF146",
                "gene_name": "RNF146",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95760-1",
                "protein_name": "Interleukin-33",
                "gene_name": "IL33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04908-1",
                "protein_name": "Histone H2A type 1-B/E",
                "gene_name": "H2AC4; H2AC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06899-1",
                "protein_name": "Histone H2B type 1-J",
                "gene_name": "H2BC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20671-1",
                "protein_name": "Histone H2A type 1-D",
                "gene_name": "H2AC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16777-1",
                "protein_name": "Histone H2A type 2-C",
                "gene_name": "H2AC20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6FI13-1",
                "protein_name": "Histone H2A type 2-A",
                "gene_name": "H2AC18; H2AC19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L7L0-1",
                "protein_name": "Histone H2A type 3",
                "gene_name": "H2AC25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IUE6-1",
                "protein_name": "Histone H2A type 2-B",
                "gene_name": "H2AC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N257-1",
                "protein_name": "Histone H2B type 3-B",
                "gene_name": "H2BC26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96QV6-1",
                "protein_name": "Histone H2A type 1-A",
                "gene_name": "H2AC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99877-1",
                "protein_name": "Histone H2B type 1-N",
                "gene_name": "H2BC15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99878-1",
                "protein_name": "Histone H2A type 1-J",
                "gene_name": "H2AC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99880-1",
                "protein_name": "Histone H2B type 1-L",
                "gene_name": "H2BC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92995-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 13",
                "gene_name": "USP13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94966-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19",
                "gene_name": "USP19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y5T5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16",
                "gene_name": "USP16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPU5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24",
                "gene_name": "USP24",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAF3-1",
                "protein_name": "WD repeat-containing protein 48",
                "gene_name": "WDR48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12933-1",
                "protein_name": "TNF receptor-associated factor 2",
                "gene_name": "TRAF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6K9-1",
                "protein_name": "NF-kappa-B essential modulator",
                "gene_name": "IKBKG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30304-1",
                "protein_name": "M-phase inducer phosphatase 1",
                "gene_name": "CDC25A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15151-1",
                "protein_name": "Protein Mdm4",
                "gene_name": "MDM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13107-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4",
                "gene_name": "USP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPT9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 22",
                "gene_name": "USP22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14964-1",
                "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate",
                "gene_name": "HGS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
                "protein_name": "Polyubiquitin-C",
                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14145-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
                "gene_name": "KEAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q00987-1",
                "protein_name": "E3 ubiquitin-protein ligase Mdm2",
                "gene_name": "MDM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75886-1",
                "protein_name": "Signal transducing adapter molecule 2",
                "gene_name": "STAM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75604-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2",
                "gene_name": "USP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10275-1",
                "protein_name": "Androgen receptor",
                "gene_name": "AR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04637-1",
                "protein_name": "Cellular tumor antigen p53",
                "gene_name": "TP53",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "O14818",
                        "url": "https://www.uniprot.org/uniprotkb/O14818"
                    }
                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
            }
        ],
        "mutagenesis": [
            {
                "start_pos": 304,
                "end_pos": 304,
                "sequence_org": "C",
                "sequence_mut": "S",
                "comment": "Loss of deubiquitinase activity. Decreased regulation of androgen receptor signaling pathway.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q9BXU7",
                        "url": "https://www.uniprot.org/uniprotkb/Q9BXU7"
                    },
                    {
                        "database": "PubMed",
                        "id": "20501646",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/20501646"
                    },
                    {
                        "database": "PubMed",
                        "id": "28839133",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/28839133"
                    }
                ],
                "uniprot_canonical_ac": "Q9BXU7-1"
            }
        ],
        "record_id": "pubmed.20501646",
        "abstract": "",
        "glycosylation": [],
        "snv": [],
        "phosphorylation": [],
        "glycation": [],
        "section_stats": [
            {
                "table_id": "referenced_proteins",
                "table_stats": [
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    {
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    {
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    {
        "title": "Polo-like kinase 1 phosphorylation of G2 and S-phase-expressed 1 protein is essential for p53 inactivation during G2 checkpoint recovery.",
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    {
        "title": "P-glycoprotein, but not multidrug resistance protein 4, plays a role in the systemic clearance of irinotecan and SN-38 in mice.",
        "journal": "Drug metabolism letters",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25963-1",
                "protein_name": "NF-kappa-B inhibitor alpha",
                "gene_name": "NFKBIA",
                "tax_name": "Human"
            },
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                "protein_name": "TNF receptor-associated factor 6",
                "gene_name": "TRAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13616-1",
                "protein_name": "Cullin-1",
                "gene_name": "CUL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P19838-1",
                "protein_name": "Nuclear factor NF-kappa-B p105 subunit",
                "gene_name": "NFKB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
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                "tax_name": "Human"
            },
            {
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                "protein_name": "High affinity immunoglobulin epsilon receptor subunit beta",
                "gene_name": "MS4A2",
                "tax_name": "Human"
            },
            {
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                "protein_name": "High affinity immunoglobulin epsilon receptor subunit gamma",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7LDG7-1",
                "protein_name": "RAS guanyl-releasing protein 2",
                "gene_name": "RASGRP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TDF6-1",
                "protein_name": "RAS guanyl-releasing protein 4",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01767-1",
                "protein_name": "Immunoglobulin heavy variable 3-53",
                "gene_name": "IGHV3-53",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06331-1",
                "protein_name": "Immunoglobulin heavy variable 4-34",
                "gene_name": "IGHV4-34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01597-1",
                "protein_name": "Immunoglobulin kappa variable 1-39",
                "gene_name": "IGKV1-39",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06310-1",
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            },
            {
                "uniprot_canonical_ac": "P06312-1",
                "protein_name": "Immunoglobulin kappa variable 4-1",
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            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
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            },
            {
                "uniprot_canonical_ac": "P01614-1",
                "protein_name": "Immunoglobulin kappa variable 2D-40",
                "gene_name": "IGKV2D-40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0DOY2-1",
                "protein_name": "Immunoglobulin lambda constant 2",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
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            },
            {
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            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
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            },
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            },
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            },
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            },
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            },
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                "uniprot_canonical_ac": "Q99436-1",
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            {
                "uniprot_canonical_ac": "O14920-1",
                "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit beta",
                "gene_name": "IKBKB",
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            },
            {
                "uniprot_canonical_ac": "Q9BXL7-1",
                "protein_name": "Caspase recruitment domain-containing protein 11",
                "gene_name": "CARD11",
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            },
            {
                "uniprot_canonical_ac": "Q9UDY8-1",
                "protein_name": "Mucosa-associated lymphoid tissue lymphoma translocation protein 1",
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                "uniprot_canonical_ac": "P51668-1",
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            },
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            },
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            {
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            },
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            },
            {
                "uniprot_canonical_ac": "P06315-1",
                "protein_name": "Immunoglobulin kappa variable 5-2",
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            },
            {
                "uniprot_canonical_ac": "P01699-1",
                "protein_name": "Immunoglobulin lambda variable 1-44",
                "gene_name": "IGLV1-44",
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            },
            {
                "uniprot_canonical_ac": "P01701-1",
                "protein_name": "Immunoglobulin lambda variable 1-51",
                "gene_name": "IGLV1-51",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01704-1",
                "protein_name": "Immunoglobulin lambda variable 2-14",
                "gene_name": "IGLV2-14",
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            },
            {
                "uniprot_canonical_ac": "P01706-1",
                "protein_name": "Immunoglobulin lambda variable 2-11",
                "gene_name": "IGLV2-11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01709-1",
                "protein_name": "Immunoglobulin lambda variable 2-8",
                "gene_name": "IGLV2-8",
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            },
            {
                "uniprot_canonical_ac": "P01717-1",
                "protein_name": "Immunoglobulin lambda variable 3-25",
                "gene_name": "IGLV3-25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01721-1",
                "protein_name": "Immunoglobulin lambda variable 6-57",
                "gene_name": "IGLV6-57",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01703-1",
                "protein_name": "Immunoglobulin lambda variable 1-40",
                "gene_name": "IGLV1-40",
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            },
            {
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                "protein_name": "Immunoglobulin lambda variable 2-23",
                "gene_name": "IGLV2-23",
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            },
            {
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                "protein_name": "Immunoglobulin lambda variable 3-1",
                "gene_name": "IGLV3-1",
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            },
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                "uniprot_canonical_ac": "P01718-1",
                "protein_name": "Immunoglobulin lambda variable 3-27",
                "gene_name": "IGLV3-27",
                "tax_name": "Human"
            },
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                "tax_name": "Human"
            },
            {
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                "protein_name": "Proteasome subunit beta type-2",
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            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P49427-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 R1",
                "gene_name": "CDC34",
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            },
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                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07948-1",
                "protein_name": "Tyrosine-protein kinase Lyn",
                "gene_name": "LYN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5C8-1",
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            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYJ8-1",
                "protein_name": "TGF-beta-activated kinase 1 and MAP3K7-binding protein 2",
                "gene_name": "TAB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q04759-1",
                "protein_name": "Protein kinase C theta type",
                "gene_name": "PRKCQ",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61088-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 N",
                "gene_name": "UBE2N",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01825-1",
                "protein_name": "Immunoglobulin heavy variable 4-59",
                "gene_name": "IGHV4-59",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01817-1",
                "protein_name": "Immunoglobulin heavy variable 2-5",
                "gene_name": "IGHV2-5",
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            },
            {
                "uniprot_canonical_ac": "P01824-1",
                "protein_name": "Immunoglobulin heavy variable 4-39",
                "gene_name": "IGHV4-39",
                "tax_name": "Human"
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            {
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                "protein_name": "Immunoglobulin heavy variable 1-2",
                "gene_name": "IGHV1-2",
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            {
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                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
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            },
            {
                "uniprot_canonical_ac": "Q15008-1",
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                "gene_name": "PSMD6",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
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                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
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            {
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                "protein_name": "Immunoglobulin heavy variable 1-69",
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                "tax_name": "Human"
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                "protein_name": "Immunoglobulin heavy variable 3-30",
                "gene_name": "IGHV3-30",
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            },
            {
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                "gene_name": "RASGRP1",
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            {
                "uniprot_canonical_ac": "P01814-1",
                "protein_name": "Immunoglobulin heavy variable 2-70",
                "gene_name": "IGHV2-70",
                "tax_name": "Human"
            },
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                "protein_name": "Immunoglobulin heavy variable 3-33",
                "gene_name": "IGHV3-33",
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            },
            {
                "uniprot_canonical_ac": "P01762-1",
                "protein_name": "Immunoglobulin heavy variable 3-11",
                "gene_name": "IGHV3-11",
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            },
            {
                "uniprot_canonical_ac": "P01763-1",
                "protein_name": "Immunoglobulin heavy variable 3-48",
                "gene_name": "IGHV3-48",
                "tax_name": "Human"
            },
            {
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                "protein_name": "Immunoglobulin heavy variable 3-23",
                "gene_name": "IGHV3-23",
                "tax_name": "Human"
            },
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                "uniprot_canonical_ac": "P01766-1",
                "protein_name": "Immunoglobulin heavy variable 3-13",
                "gene_name": "IGHV3-13",
                "tax_name": "Human"
            },
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                "protein_name": "Immunoglobulin heavy variable 3-7",
                "gene_name": "IGHV3-7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01782-1",
                "protein_name": "Immunoglobulin heavy variable 3-9",
                "gene_name": "IGHV3-9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A0M8Q6-1",
                "protein_name": "Immunoglobulin lambda constant 7",
                "gene_name": "IGLC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01834-1",
                "protein_name": "Immunoglobulin kappa constant",
                "gene_name": "IGKC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG04-1",
                "protein_name": "Immunoglobulin lambda constant 1",
                "gene_name": "IGLC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0DOY3-1",
                "protein_name": "Immunoglobulin lambda constant 3",
                "gene_name": "IGLC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01743-1",
                "protein_name": "Immunoglobulin heavy variable 1-46",
                "gene_name": "IGHV1-46",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01854-2",
                "protein_name": "Immunoglobulin heavy constant epsilon",
                "gene_name": "IGHE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13404-4",
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            },
            {
                "uniprot_canonical_ac": "A0A0C4DH73-1",
                "protein_name": "Immunoglobulin kappa variable 1-12",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A2NJV5-1",
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                "protein_name": "NF-kappa-B essential modulator",
                "gene_name": "IKBKG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
                "protein_name": "Polyubiquitin-C",
                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63208-1",
                "protein_name": "S-phase kinase-associated protein 1",
                "gene_name": "SKP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q04206-1",
                "protein_name": "Transcription factor p65",
                "gene_name": "RELA",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O15530-1",
                "protein_name": "3-phosphoinositide-dependent protein kinase 1",
                "gene_name": "PDPK1",
                "tax_name": "Human"
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        ],
        "species": [
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                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                        "database": "UniProtKB",
                        "id": "O14818",
                        "url": "https://www.uniprot.org/uniprotkb/O14818"
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                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.20685844",
        "abstract": "",
        "glycosylation": [],
        "mutagenesis": [],
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        "phosphorylation": [],
        "glycation": [],
        "section_stats": [
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    {
        "title": "Serine residue 115 of MAPK-activated protein kinase MK5 is crucial for its PKA-regulated nuclear export and biological function.",
        "journal": "Cellular and molecular life sciences : CMLS",
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        "authors": "Kostenko S, Shiryaev A, Gerits N, Dumitriu G, Klenow H, Johannessen M, Moens U",
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        "title": "The ubiquitin carboxyl hydrolase BAP1 forms a ternary complex with YY1 and HCF-1 and is a critical regulator of gene expression.",
        "journal": "Molecular and cellular biology",
        "date": "2010",
        "authors": "Yu H, Mashtalir N, Daou S, Hammond-Martel I, Ross J, Sui G, Hart GW, Rauscher FJ 3rd, Drobetsky E, Milot E, Shi Y, Affar el B",
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    {
        "title": "G protein-coupled receptor kinase 2 promotes high-level Hedgehog signaling by regulating the active state of Smo through kinase-dependent and kinase-independent mechanisms in Drosophila.",
        "journal": "Genes &amp; development",
        "date": "2010",
        "authors": "Chen Y, Li S, Tong C, Zhao Y, Wang B, Liu Y, Jia J, Jiang J",
        "reference": {
            "type": "PubMed",
            "id": "20844016",
            "url": "https://pubmed.ncbi.nlm.nih.gov/20844016"
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        "title": "The protein stability of Axin, a negative regulator of Wnt signaling, is regulated by Smad ubiquitination regulatory factor 2 (Smurf2).",
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                "protein_name": "Tubulin beta-2B chain",
                "gene_name": "TUBB2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2H3-1",
                "protein_name": "Intraflagellar transport protein 80 homolog",
                "gene_name": "IFT80",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVS4-1",
                "protein_name": "Cytoplasmic dynein 2 intermediate chain 1",
                "gene_name": "DYNC2I1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99835-1",
                "protein_name": "Protein smoothened",
                "gene_name": "SMO",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TDR0-1",
                "protein_name": "TRAF3-interacting protein 1",
                "gene_name": "TRAF3IP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96J02-1",
                "protein_name": "E3 ubiquitin-protein ligase Itchy homolog",
                "gene_name": "ITCH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96AJ1-1",
                "protein_name": "Clusterin-associated protein 1",
                "gene_name": "CLUAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49757-1",
                "protein_name": "Protein numb homolog",
                "gene_name": "NUMB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9ULD6-1",
                "protein_name": "Protein inturned",
                "gene_name": "INTU",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TCX1-1",
                "protein_name": "Cytoplasmic dynein 2 light intermediate chain 1",
                "gene_name": "DYNC2LI1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NP97-1",
                "protein_name": "Dynein light chain roadblock-type 1",
                "gene_name": "DYNLRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UK5-1",
                "protein_name": "Limbin",
                "gene_name": "EVC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P22612-1",
                "protein_name": "cAMP-dependent protein kinase catalytic subunit gamma",
                "gene_name": "PRKACG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14782-1",
                "protein_name": "Kinesin-like protein KIF3C",
                "gene_name": "KIF3C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q2M1P5-1",
                "protein_name": "Kinesin-like protein KIF7",
                "gene_name": "KIF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92845-1",
                "protein_name": "Kinesin-associated protein 3",
                "gene_name": "KIFAP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BUF5-1",
                "protein_name": "Tubulin beta-6 chain",
                "gene_name": "TUBB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q68CZ1-1",
                "protein_name": "Protein fantom",
                "gene_name": "RPGRIP1L",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04350-1",
                "protein_name": "Tubulin beta-4A chain",
                "gene_name": "TUBB4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A0AVF1-1",
                "protein_name": "Intraflagellar transport protein 56",
                "gene_name": "IFT56",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N6U8-1",
                "protein_name": "G protein-coupled receptor 161",
                "gene_name": "GPR161",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NCM8-1",
                "protein_name": "Cytoplasmic dynein 2 heavy chain 1",
                "gene_name": "DYNC2H1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13861-1",
                "protein_name": "cAMP-dependent protein kinase type II-alpha regulatory subunit",
                "gene_name": "PRKAR2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13885-1",
                "protein_name": "Tubulin beta-2A chain",
                "gene_name": "TUBB2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YF9-1",
                "protein_name": "Cilium assembly protein DZIP1",
                "gene_name": "DZIP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08151-1",
                "protein_name": "Transcription activator GLI1",
                "gene_name": "GLI1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17612-1",
                "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha",
                "gene_name": "PRKACA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63167-1",
                "protein_name": "Dynein light chain 1, cytoplasmic",
                "gene_name": "DYNLL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75386-1",
                "protein_name": "Tubby-related protein 3",
                "gene_name": "TULP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95622-1",
                "protein_name": "Adenylate cyclase type 5",
                "gene_name": "ADCY5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q08828-1",
                "protein_name": "Adenylate cyclase type 1",
                "gene_name": "ADCY1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40145-1",
                "protein_name": "Adenylate cyclase type 8",
                "gene_name": "ADCY8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60266-1",
                "protein_name": "Adenylate cyclase type 3",
                "gene_name": "ADCY3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NFM4-1",
                "protein_name": "Adenylate cyclase type 4",
                "gene_name": "ADCY4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WW35-1",
                "protein_name": "Dynein light chain Tctex-type protein 2B",
                "gene_name": "DYNLT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10644-1",
                "protein_name": "cAMP-dependent protein kinase type I-alpha regulatory subunit",
                "gene_name": "PRKAR1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31323-1",
                "protein_name": "cAMP-dependent protein kinase type II-beta regulatory subunit",
                "gene_name": "PRKAR2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EX3-1",
                "protein_name": "Cytoplasmic dynein 2 intermediate chain 2",
                "gene_name": "DYNC2I2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43791-1",
                "protein_name": "Speckle-type POZ protein",
                "gene_name": "SPOP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57679-1",
                "protein_name": "EvC complex member EVC",
                "gene_name": "EVC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCE7-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF1",
                "gene_name": "SMURF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92973-1",
                "protein_name": "Transportin-1",
                "gene_name": "TNPO1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86WT1-1",
                "protein_name": "Intraflagellar transport protein 70A",
                "gene_name": "IFT70A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0DPH8-1",
                "protein_name": "Tubulin alpha-3D chain",
                "gene_name": "TUBA3D",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31321-1",
                "protein_name": "cAMP-dependent protein kinase type I-beta regulatory subunit",
                "gene_name": "PRKAR1B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P1J9-1",
                "protein_name": "Parafibromin",
                "gene_name": "CDC73",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N4P2-1",
                "protein_name": "Intraflagellar transport protein 70B",
                "gene_name": "IFT70B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75665-1",
                "protein_name": "Centriole and centriolar satellite protein OFD1",
                "gene_name": "OFD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FJ2-1",
                "protein_name": "Dynein light chain 2, cytoplasmic",
                "gene_name": "DYNLL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TF09-1",
                "protein_name": "Dynein light chain roadblock-type 2",
                "gene_name": "DYNLRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LB3-1",
                "protein_name": "Intraflagellar transport protein 74 homolog",
                "gene_name": "IFT74",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2E2-1",
                "protein_name": "Kinesin-like protein KIF17",
                "gene_name": "KIF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC8-1",
                "protein_name": "Intraflagellar transport protein 46 homolog",
                "gene_name": "IFT46",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FT9-1",
                "protein_name": "Intraflagellar transport protein 43 homolog",
                "gene_name": "IFT43",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7X7-1",
                "protein_name": "Intraflagellar transport protein 22 homolog",
                "gene_name": "IFT22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y547-1",
                "protein_name": "Intraflagellar transport protein 25 homolog",
                "gene_name": "IFT25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14623-1",
                "protein_name": "Indian hedgehog protein",
                "gene_name": "IHH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y366-1",
                "protein_name": "Intraflagellar transport protein 52 homolog",
                "gene_name": "IFT52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13509-1",
                "protein_name": "Tubulin beta-3 chain",
                "gene_name": "TUBB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BQE3-1",
                "protein_name": "Tubulin alpha-1C chain",
                "gene_name": "TUBA1C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P68371-1",
                "protein_name": "Tubulin beta-4B chain",
                "gene_name": "TUBB4B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4B7-1",
                "protein_name": "Tubulin beta-1 chain",
                "gene_name": "TUBB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4L5-1",
                "protein_name": "Tetratricopeptide repeat protein 21B",
                "gene_name": "TTC21B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PHR2-1",
                "protein_name": "Serine/threonine-protein kinase ULK3",
                "gene_name": "ULK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWB7-1",
                "protein_name": "Intraflagellar transport protein 57 homolog",
                "gene_name": "IFT57",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT04-1",
                "protein_name": "Protein fuzzy homolog",
                "gene_name": "FUZ",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10071-1",
                "protein_name": "Transcription activator GLI3",
                "gene_name": "GLI3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMX1-1",
                "protein_name": "Suppressor of fused homolog",
                "gene_name": "SUFU",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6IQ16-1",
                "protein_name": "Speckle-type POZ protein-like",
                "gene_name": "SPOPL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13099-2",
                "protein_name": "Intraflagellar transport protein 88 homolog",
                "gene_name": "IFT88",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WYA0-1",
                "protein_name": "Intraflagellar transport protein 81 homolog",
                "gene_name": "IFT81",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXB0-1",
                "protein_name": "Tectonic-like complex member MKS1",
                "gene_name": "MKS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N7M0-1",
                "protein_name": "Dynein light chain Tctex-type 5",
                "gene_name": "DYNLT5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IZS6-1",
                "protein_name": "Dynein light chain Tctex-type protein 2",
                "gene_name": "DYNLT2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10070-5",
                "protein_name": "Transcription activator GLI2",
                "gene_name": "GLI2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15643-1",
                "protein_name": "Thyroid receptor-interacting protein 11",
                "gene_name": "TRIP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEZ3-1",
                "protein_name": "WD repeat-containing protein 19",
                "gene_name": "WDR19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0DPH7-1",
                "protein_name": "Tubulin alpha-3C chain",
                "gene_name": "TUBA3C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60503-1",
                "protein_name": "Adenylate cyclase type 9",
                "gene_name": "ADCY9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PN6-1",
                "protein_name": "Adenylate cyclase type 10",
                "gene_name": "ADCY10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51828-1",
                "protein_name": "Adenylate cyclase type 7",
                "gene_name": "ADCY7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
                "protein_name": "Polyubiquitin-C",
                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43306-1",
                "protein_name": "Adenylate cyclase type 6",
                "gene_name": "ADCY6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q08462-1",
                "protein_name": "Adenylate cyclase type 2",
                "gene_name": "ADCY2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IY31-1",
                "protein_name": "Intraflagellar transport protein 20 homolog",
                "gene_name": "IFT20",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
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        "title": "The GAP-related domain of the neurofibromatosis type 1 gene product interacts with ras p21.",
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    {
        "title": "Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y256-1",
                "protein_name": "CAAX prenyl protease 2",
                "gene_name": "RCE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NTX7-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF146",
                "gene_name": "RNF146",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95760-1",
                "protein_name": "Interleukin-33",
                "gene_name": "IL33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04908-1",
                "protein_name": "Histone H2A type 1-B/E",
                "gene_name": "H2AC4; H2AC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06899-1",
                "protein_name": "Histone H2B type 1-J",
                "gene_name": "H2BC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20671-1",
                "protein_name": "Histone H2A type 1-D",
                "gene_name": "H2AC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16777-1",
                "protein_name": "Histone H2A type 2-C",
                "gene_name": "H2AC20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6FI13-1",
                "protein_name": "Histone H2A type 2-A",
                "gene_name": "H2AC18; H2AC19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L7L0-1",
                "protein_name": "Histone H2A type 3",
                "gene_name": "H2AC25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IUE6-1",
                "protein_name": "Histone H2A type 2-B",
                "gene_name": "H2AC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N257-1",
                "protein_name": "Histone H2B type 3-B",
                "gene_name": "H2BC26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96QV6-1",
                "protein_name": "Histone H2A type 1-A",
                "gene_name": "H2AC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99877-1",
                "protein_name": "Histone H2B type 1-N",
                "gene_name": "H2BC15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99878-1",
                "protein_name": "Histone H2A type 1-J",
                "gene_name": "H2AC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99880-1",
                "protein_name": "Histone H2B type 1-L",
                "gene_name": "H2BC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92995-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 13",
                "gene_name": "USP13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94966-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19",
                "gene_name": "USP19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y5T5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16",
                "gene_name": "USP16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPU5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24",
                "gene_name": "USP24",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAF3-1",
                "protein_name": "WD repeat-containing protein 48",
                "gene_name": "WDR48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12933-1",
                "protein_name": "TNF receptor-associated factor 2",
                "gene_name": "TRAF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6K9-1",
                "protein_name": "NF-kappa-B essential modulator",
                "gene_name": "IKBKG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30304-1",
                "protein_name": "M-phase inducer phosphatase 1",
                "gene_name": "CDC25A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15151-1",
                "protein_name": "Protein Mdm4",
                "gene_name": "MDM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13107-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4",
                "gene_name": "USP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPT9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 22",
                "gene_name": "USP22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14964-1",
                "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate",
                "gene_name": "HGS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
                "protein_name": "Polyubiquitin-C",
                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14145-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
                "gene_name": "KEAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q00987-1",
                "protein_name": "E3 ubiquitin-protein ligase Mdm2",
                "gene_name": "MDM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75886-1",
                "protein_name": "Signal transducing adapter molecule 2",
                "gene_name": "STAM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75604-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2",
                "gene_name": "USP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10275-1",
                "protein_name": "Androgen receptor",
                "gene_name": "AR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04637-1",
                "protein_name": "Cellular tumor antigen p53",
                "gene_name": "TP53",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "O14818",
                        "url": "https://www.uniprot.org/uniprotkb/O14818"
                    }
                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        "title": "The MK5/PRAK kinase and Myc form a negative feedback loop that is disrupted during colorectal tumorigenesis.",
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    {
        "title": "USP47 is a deubiquitylating enzyme that regulates base excision repair by controlling steady-state levels of DNA polymerase beta.",
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        "date": "2011",
        "authors": "Parsons JL, Dianova II, Khoronenkova SV, Edelmann MJ, Kessler BM, Dianov GL",
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                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14735-1",
                "protein_name": "Insulin-degrading enzyme",
                "gene_name": "IDE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
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                "protein_name": "Glutamate receptor ionotropic, NMDA 2D",
                "gene_name": "GRIN2D",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15211-1",
                "protein_name": "Ral guanine nucleotide dissociation stimulator-like 2",
                "gene_name": "RGL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01589-1",
                "protein_name": "Interleukin-2 receptor subunit alpha",
                "gene_name": "IL2RA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60542-1",
                "protein_name": "Persephin",
                "gene_name": "PSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14511-1",
                "protein_name": "Pro-neuregulin-2, membrane-bound isoform",
                "gene_name": "NRG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q3MIN7-1",
                "protein_name": "Ral guanine nucleotide dissociation stimulator-like 3",
                "gene_name": "RGL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13972-1",
                "protein_name": "Ras-specific guanine nucleotide-releasing factor 1",
                "gene_name": "RASGRF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05397-1",
                "protein_name": "Focal adhesion kinase 1",
                "gene_name": "PTK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30281-1",
                "protein_name": "G1/S-specific cyclin-D3",
                "gene_name": "CCND3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15700-1",
                "protein_name": "Disks large homolog 2",
                "gene_name": "DLG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13224-1",
                "protein_name": "Glutamate receptor ionotropic, NMDA 2B",
                "gene_name": "GRIN2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25685-1",
                "protein_name": "DnaJ homolog subfamily B member 1",
                "gene_name": "DNAJB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01135-1",
                "protein_name": "Protransforming growth factor alpha",
                "gene_name": "TGFA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98077-1",
                "protein_name": "SHC-transforming protein 2",
                "gene_name": "SHC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q01082-1",
                "protein_name": "Spectrin beta chain, non-erythrocytic 1",
                "gene_name": "SPTBN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H254-1",
                "protein_name": "Spectrin beta chain, non-erythrocytic 4",
                "gene_name": "SPTBN4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P39905-1",
                "protein_name": "Glial cell line-derived neurotrophic factor",
                "gene_name": "GDNF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6Q9-1",
                "protein_name": "Nuclear receptor coactivator 3",
                "gene_name": "NCOA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06493-1",
                "protein_name": "Cyclin-dependent kinase 1",
                "gene_name": "CDK1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0DP23-1",
                "protein_name": "Calmodulin-1",
                "gene_name": "CALM1; CALM2; CALM3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60729-1",
                "protein_name": "Dual specificity protein phosphatase CDC14B",
                "gene_name": "CDC14B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKI2-1",
                "protein_name": "Cdc42 effector protein 3",
                "gene_name": "CDC42EP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09038-4",
                "protein_name": "Fibroblast growth factor 2",
                "gene_name": "FGF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNH5-1",
                "protein_name": "Dual specificity protein phosphatase CDC14A",
                "gene_name": "CDC14A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75914-1",
                "protein_name": "Serine/threonine-protein kinase PAK 3",
                "gene_name": "PAK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NW7-4",
                "protein_name": "Leucine-rich repeat-containing protein 7",
                "gene_name": "LRRC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P52333-1",
                "protein_name": "Tyrosine-protein kinase JAK3",
                "gene_name": "JAK3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60229-1",
                "protein_name": "Kalirin",
                "gene_name": "KALRN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P22612-1",
                "protein_name": "cAMP-dependent protein kinase catalytic subunit gamma",
                "gene_name": "PRKACG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99748-1",
                "protein_name": "Neurturin",
                "gene_name": "NRTN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P11277-1",
                "protein_name": "Spectrin beta chain, erythrocytic",
                "gene_name": "SPTB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRC6-1",
                "protein_name": "Spectrin beta chain, non-erythrocytic 5",
                "gene_name": "SPTBN5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q07889-1",
                "protein_name": "Son of sevenless homolog 1",
                "gene_name": "SOS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78352-1",
                "protein_name": "Disks large homolog 4",
                "gene_name": "DLG4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04141-1",
                "protein_name": "Granulocyte-macrophage colony-stimulating factor",
                "gene_name": "CSF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32927-1",
                "protein_name": "Cytokine receptor common subunit beta",
                "gene_name": "CSF2RB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P16234-1",
                "protein_name": "Platelet-derived growth factor receptor alpha",
                "gene_name": "PDGFRA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10767-1",
                "protein_name": "Fibroblast growth factor 6",
                "gene_name": "FGF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43320-1",
                "protein_name": "Fibroblast growth factor 16",
                "gene_name": "FGF16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95750-1",
                "protein_name": "Fibroblast growth factor 19",
                "gene_name": "FGF19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08620-1",
                "protein_name": "Fibroblast growth factor 4",
                "gene_name": "FGF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P11487-1",
                "protein_name": "Fibroblast growth factor 3",
                "gene_name": "FGF3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21781-1",
                "protein_name": "Fibroblast growth factor 7",
                "gene_name": "FGF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00451-1",
                "protein_name": "GDNF family receptor alpha-2",
                "gene_name": "GFRA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31371-1",
                "protein_name": "Fibroblast growth factor 9",
                "gene_name": "FGF9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43268-1",
                "protein_name": "ETS translocation variant 4",
                "gene_name": "ETV4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92796-1",
                "protein_name": "Disks large homolog 3",
                "gene_name": "DLG3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35609-1",
                "protein_name": "Alpha-actinin-2",
                "gene_name": "ACTN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14980-1",
                "protein_name": "Exportin-1",
                "gene_name": "XPO1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04792-1",
                "protein_name": "Heat shock protein beta-1",
                "gene_name": "HSPB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43524-1",
                "protein_name": "Forkhead box protein O3",
                "gene_name": "FOXO3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4H2-1",
                "protein_name": "Insulin receptor substrate 2",
                "gene_name": "IRS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P02549-1",
                "protein_name": "Spectrin alpha chain, erythrocytic 1",
                "gene_name": "SPTA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60953-2",
                "protein_name": "Cell division control protein 42 homolog",
                "gene_name": "CDC42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17612-1",
                "protein_name": "cAMP-dependent protein kinase catalytic subunit alpha",
                "gene_name": "PRKACA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKV8-1",
                "protein_name": "Protein argonaute-2",
                "gene_name": "AGO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12959-1",
                "protein_name": "Disks large homolog 1",
                "gene_name": "DLG1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63000-1",
                "protein_name": "Ras-related C3 botulinum toxin substrate 1",
                "gene_name": "RAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00459-1",
                "protein_name": "Phosphatidylinositol 3-kinase regulatory subunit beta",
                "gene_name": "PIK3R2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q06124-2",
                "protein_name": "Tyrosine-protein phosphatase non-receptor type 11",
                "gene_name": "PTPN11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43559-1",
                "protein_name": "Fibroblast growth factor receptor substrate 3",
                "gene_name": "FRS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9G7-1",
                "protein_name": "Protein argonaute-3",
                "gene_name": "AGO3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NDV7-1",
                "protein_name": "Trinucleotide repeat-containing gene 6A protein",
                "gene_name": "TNRC6A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15509-1",
                "protein_name": "Granulocyte-macrophage colony-stimulating factor receptor subunit alpha",
                "gene_name": "CSF2RA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36888-1",
                "protein_name": "Receptor-type tyrosine-protein kinase FLT3",
                "gene_name": "FLT3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P05230-1",
                "protein_name": "Fibroblast growth factor 1",
                "gene_name": "FGF1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P09619-1",
                "protein_name": "Platelet-derived growth factor receptor beta",
                "gene_name": "PDGFRB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCT0-1",
                "protein_name": "Fibroblast growth factor 22",
                "gene_name": "FGF22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O76093-1",
                "protein_name": "Fibroblast growth factor 18",
                "gene_name": "FGF18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14210-1",
                "protein_name": "Hepatocyte growth factor",
                "gene_name": "HGF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13557-1",
                "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit delta",
                "gene_name": "CAMK2D",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HCE1-1",
                "protein_name": "RNA helicase MOV-10",
                "gene_name": "MOV10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35568-1",
                "protein_name": "Insulin receptor substrate 1",
                "gene_name": "IRS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P18433-5",
                "protein_name": "Receptor-type tyrosine-protein phosphatase alpha",
                "gene_name": "PTPRA",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P42338-1",
                "protein_name": "Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform",
                "gene_name": "PIK3CB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15918-1",
                "protein_name": "V(D)J recombination-activating protein 1",
                "gene_name": "RAG1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55895-1",
                "protein_name": "V(D)J recombination-activating protein 2",
                "gene_name": "RAG2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13555-1",
                "protein_name": "Calcium/calmodulin-dependent protein kinase type II subunit gamma",
                "gene_name": "CAMK2G",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P31152-1",
                "protein_name": "Mitogen-activated protein kinase 4",
                "gene_name": "MAPK4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95267-1",
                "protein_name": "RAS guanyl-releasing protein 1",
                "gene_name": "RASGRP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01127-1",
                "protein_name": "Platelet-derived growth factor subunit B",
                "gene_name": "PDGFB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL6-1",
                "protein_name": "Ral guanine nucleotide dissociation stimulator-like 1",
                "gene_name": "RGL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15020-1",
                "protein_name": "Spectrin beta chain, non-erythrocytic 2",
                "gene_name": "SPTBN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13591-2",
                "protein_name": "Neural cell adhesion molecule 1",
                "gene_name": "NCAM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05586-1",
                "protein_name": "Glutamate receptor ionotropic, NMDA 1",
                "gene_name": "GRIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P08581-1",
                "protein_name": "Hepatocyte growth factor receptor",
                "gene_name": "MET",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35070-1",
                "protein_name": "Probetacellulin",
                "gene_name": "BTC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14613-1",
                "protein_name": "Cdc42 effector protein 2",
                "gene_name": "CDC42EP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6NZY7-1",
                "protein_name": "Cdc42 effector protein 5",
                "gene_name": "CDC42EP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P27361-1",
                "protein_name": "Mitogen-activated protein kinase 3",
                "gene_name": "MAPK3",
                "tax_name": "Human"
            },
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    {
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
                "protein_name": "COP9 signalosome complex subunit 5",
                "gene_name": "COPS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13619-1",
                "protein_name": "Cullin-4A",
                "gene_name": "CUL4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VP6-1",
                "protein_name": "Cullin-associated NEDD8-dissociated protein 1",
                "gene_name": "CAND1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13620-2",
                "protein_name": "Cullin-4B",
                "gene_name": "CUL4B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0C5-1",
                "protein_name": "BTB/POZ domain-containing protein 1",
                "gene_name": "BTBD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXF7-1",
                "protein_name": "DDB1- and CUL4-associated factor 16",
                "gene_name": "DCAF16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2N7-1",
                "protein_name": "Hypoxia-inducible factor 3-alpha",
                "gene_name": "HIF3A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NCQ5-1",
                "protein_name": "F-box only protein 15",
                "gene_name": "FBXO15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK96-1",
                "protein_name": "F-box only protein 10",
                "gene_name": "FBXO10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
                "gene_name": "FBXO30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JP0-1",
                "protein_name": "Protein fem-1 homolog C",
                "gene_name": "FEM1C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH90-1",
                "protein_name": "F-box only protein 40",
                "gene_name": "FBXO40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969M7-1",
                "protein_name": "NEDD8-conjugating enzyme UBE2F",
                "gene_name": "UBE2F-SCLY; UBE2F",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LD8-1",
                "protein_name": "Sentrin-specific protease 8",
                "gene_name": "SENP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13564-1",
                "protein_name": "NEDD8-activating enzyme E1 regulatory subunit",
                "gene_name": "NAE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95198-1",
                "protein_name": "Kelch-like protein 2",
                "gene_name": "KLHL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P38936-1",
                "protein_name": "Cyclin-dependent kinase inhibitor 1",
                "gene_name": "CDKN1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXK8-1",
                "protein_name": "F-box/LRR-repeat protein 12",
                "gene_name": "FBXL12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT8-1",
                "protein_name": "F-box/WD repeat-containing protein 2",
                "gene_name": "FBXW2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEB1-1",
                "protein_name": "DDB1- and CUL4-associated factor 11",
                "gene_name": "DCAF11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB72-1",
                "protein_name": "Pumilio homolog 2",
                "gene_name": "PUM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BTE7-1",
                "protein_name": "DCN1-like protein 5",
                "gene_name": "DCUN1D5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q58WW2-1",
                "protein_name": "DDB1- and CUL4-associated factor 6",
                "gene_name": "DCAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PH85-1",
                "protein_name": "DCN1-like protein 2",
                "gene_name": "DCUN1D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92564-1",
                "protein_name": "DCN1-like protein 4",
                "gene_name": "DCUN1D4",
                "tax_name": "Human"
            },
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                "tax_name": "Human"
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9Y576-1",
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                "tax_name": "Human"
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                "protein_name": "Endothelial PAS domain-containing protein 1",
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                "uniprot_canonical_ac": "Q9BW61-1",
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                "tax_name": "Human"
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                "protein_name": "COP9 signalosome complex subunit 2",
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                "tax_name": "Human"
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            {
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                "uniprot_canonical_ac": "Q9H0W5-1",
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                "uniprot_canonical_ac": "Q86X83-1",
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                "tax_name": "Human"
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                "tax_name": "Human"
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                "protein_name": "COMM domain-containing protein 5",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "P61962-1",
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                "uniprot_canonical_ac": "Q8WV16-1",
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                "tax_name": "Human"
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                "protein_name": "Kelch-like protein 22",
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                "uniprot_canonical_ac": "Q5QP82-1",
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                "gene_name": "DCAF10",
                "tax_name": "Human"
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                "protein_name": "Kelch-like protein 41",
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                "protein_name": "LIM domain only protein 7",
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                "protein_name": "Kelch-like protein 11",
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                "tax_name": "Human"
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                "protein_name": "Proteasome subunit beta type-2",
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                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
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                "tax_name": "Human"
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                "protein_name": "Ubiquitin D",
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                "protein_name": "Nuclear factor erythroid 2-related factor 2",
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                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
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                "uniprot_canonical_ac": "Q9Y6I7-1",
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                "protein_name": "COP9 signalosome complex subunit 7b",
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                "uniprot_canonical_ac": "O94888-1",
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                "protein_name": "COP9 signalosome complex subunit 1",
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                "protein_name": "E3 ubiquitin-protein ligase RBX1",
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                "protein_name": "Ubiquitin-like protein NEDD8",
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                "protein_name": "Transitional endoplasmic reticulum ATPase",
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                "gene_name": "PSMA1",
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                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
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            {
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                "protein_name": "COP9 signalosome complex subunit 6",
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            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
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            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
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                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
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                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q8IWE4-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
                "protein_name": "COP9 signalosome complex subunit 5",
                "gene_name": "COPS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13619-1",
                "protein_name": "Cullin-4A",
                "gene_name": "CUL4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VP6-1",
                "protein_name": "Cullin-associated NEDD8-dissociated protein 1",
                "gene_name": "CAND1",
                "tax_name": "Human"
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    {
        "title": "RNF146 is a poly(ADP-ribose)-directed E3 ligase that regulates axin degradation and Wnt signalling.",
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        "date": "2011",
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                "protein_name": "Ubiquitin recognition factor in ER-associated degradation protein 1",
                "gene_name": "UFD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 49",
                "gene_name": "USP49",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40818-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 8",
                "gene_name": "USP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95271-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-1",
                "gene_name": "TNKS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93009-1",
                "protein_name": "Ubiquitin C-terminal hydrolase 7",
                "gene_name": "USP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2K6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 20",
                "gene_name": "USP20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14318-1",
                "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP8",
                "gene_name": "FKBP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78396-1",
                "protein_name": "Cyclin-A1",
                "gene_name": "CCNA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43303-1",
                "protein_name": "Centriolar coiled-coil protein of 110 kDa",
                "gene_name": "CCP110",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14735-1",
                "protein_name": "Insulin-degrading enzyme",
                "gene_name": "IDE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
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    {
        "title": "Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry.",
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                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95271-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-1",
                "gene_name": "TNKS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93009-1",
                "protein_name": "Ubiquitin C-terminal hydrolase 7",
                "gene_name": "USP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2K6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 20",
                "gene_name": "USP20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14318-1",
                "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP8",
                "gene_name": "FKBP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78396-1",
                "protein_name": "Cyclin-A1",
                "gene_name": "CCNA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43303-1",
                "protein_name": "Centriolar coiled-coil protein of 110 kDa",
                "gene_name": "CCP110",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14735-1",
                "protein_name": "Insulin-degrading enzyme",
                "gene_name": "IDE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P24941-1",
                "protein_name": "Cyclin-dependent kinase 2",
                "gene_name": "CDK2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UM11-1",
                "protein_name": "Fizzy-related protein homolog",
                "gene_name": "FZR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y256-1",
                "protein_name": "CAAX prenyl protease 2",
                "gene_name": "RCE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NTX7-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF146",
                "gene_name": "RNF146",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95760-1",
                "protein_name": "Interleukin-33",
                "gene_name": "IL33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04908-1",
                "protein_name": "Histone H2A type 1-B/E",
                "gene_name": "H2AC4; H2AC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06899-1",
                "protein_name": "Histone H2B type 1-J",
                "gene_name": "H2BC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20671-1",
                "protein_name": "Histone H2A type 1-D",
                "gene_name": "H2AC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16777-1",
                "protein_name": "Histone H2A type 2-C",
                "gene_name": "H2AC20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6FI13-1",
                "protein_name": "Histone H2A type 2-A",
                "gene_name": "H2AC18; H2AC19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L7L0-1",
                "protein_name": "Histone H2A type 3",
                "gene_name": "H2AC25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IUE6-1",
                "protein_name": "Histone H2A type 2-B",
                "gene_name": "H2AC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N257-1",
                "protein_name": "Histone H2B type 3-B",
                "gene_name": "H2BC26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96QV6-1",
                "protein_name": "Histone H2A type 1-A",
                "gene_name": "H2AC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99877-1",
                "protein_name": "Histone H2B type 1-N",
                "gene_name": "H2BC15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99878-1",
                "protein_name": "Histone H2A type 1-J",
                "gene_name": "H2AC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99880-1",
                "protein_name": "Histone H2B type 1-L",
                "gene_name": "H2BC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92995-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 13",
                "gene_name": "USP13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94966-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19",
                "gene_name": "USP19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y5T5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16",
                "gene_name": "USP16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPU5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24",
                "gene_name": "USP24",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAF3-1",
                "protein_name": "WD repeat-containing protein 48",
                "gene_name": "WDR48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12933-1",
                "protein_name": "TNF receptor-associated factor 2",
                "gene_name": "TRAF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6K9-1",
                "protein_name": "NF-kappa-B essential modulator",
                "gene_name": "IKBKG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30304-1",
                "protein_name": "M-phase inducer phosphatase 1",
                "gene_name": "CDC25A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15151-1",
                "protein_name": "Protein Mdm4",
                "gene_name": "MDM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13107-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4",
                "gene_name": "USP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPT9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 22",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14964-1",
                "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate",
                "gene_name": "HGS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
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                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14145-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
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                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q00987-1",
                "protein_name": "E3 ubiquitin-protein ligase Mdm2",
                "gene_name": "MDM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75886-1",
                "protein_name": "Signal transducing adapter molecule 2",
                "gene_name": "STAM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75604-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2",
                "gene_name": "USP2",
                "tax_name": "Human"
            },
            {
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                "protein_name": "Androgen receptor",
                "gene_name": "AR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04637-1",
                "protein_name": "Cellular tumor antigen p53",
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                "tax_name": "Human"
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        ],
        "species": [
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                "name": "Homo sapiens",
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                        "id": "O14818",
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                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
            }
        ],
        "mutagenesis": [
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                "start_pos": 160,
                "end_pos": 163,
                "sequence_org": "RKVL",
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                "comment": "No effect.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q86T82",
                        "url": "https://www.uniprot.org/uniprotkb/Q86T82"
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            },
            {
                "start_pos": 221,
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                "sequence_org": "KEN",
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                "comment": "No effect.",
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                        "id": "Q86T82",
                        "url": "https://www.uniprot.org/uniprotkb/Q86T82"
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            {
                "start_pos": 32,
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                "sequence_org": "KEN",
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                "comment": "No effect.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q86T82",
                        "url": "https://www.uniprot.org/uniprotkb/Q86T82"
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                    {
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/21596315"
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                ],
                "uniprot_canonical_ac": "Q86T82-1"
            },
            {
                "start_pos": 350,
                "end_pos": 350,
                "sequence_org": "C",
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                "comment": "Abolishes deubiquitinase activity.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q86T82",
                        "url": "https://www.uniprot.org/uniprotkb/Q86T82"
                    },
                    {
                        "database": "PubMed",
                        "id": "21596315",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/21596315"
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                ],
                "uniprot_canonical_ac": "Q86T82-1"
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            {
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                "sequence_org": "S",
                "sequence_mut": "A",
                "comment": "Abolishes phosphorylation by CDK2, leading to lower deubiquitinase activity.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q86T82",
                        "url": "https://www.uniprot.org/uniprotkb/Q86T82"
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                    {
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            },
            {
                "start_pos": 71,
                "end_pos": 74,
                "sequence_org": "RLML",
                "sequence_mut": "ALMA",
                "comment": "No effect.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q86T82",
                        "url": "https://www.uniprot.org/uniprotkb/Q86T82"
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                    {
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                "sequence_org": "KEN",
                "sequence_mut": "AAA",
                "comment": "Impaired interaction with FZR1/CDH1 and subsequent ubiquitination.",
                "evidence": [
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                "start_pos": 96,
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                "sequence_org": "RLFL",
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                "comment": "No effect.",
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "Q86T82",
                        "url": "https://www.uniprot.org/uniprotkb/Q86T82"
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                "comment": "",
                "evidence": [
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                "kinase_uniprot_canonical_ac": "",
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                "residue": "Ser",
                "comment": "Phosphoserine; by CDK2",
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                "site_lbl": "Ser628",
                "uniprot_canonical_ac": "Q86T82-1"
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        ],
        "record_id": "pubmed.21596315",
        "abstract": "",
        "glycosylation": [],
        "snv": [],
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        "section_stats": [
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        ]
    },
    {
        "title": "Cystic fibrosis transmembrane conductance regulator intracellular processing, trafficking, and opportunities for mutation-specific treatment.",
        "journal": "Chest",
        "date": "2011",
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                "gene_name": "FKBP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P78396-1",
                "protein_name": "Cyclin-A1",
                "gene_name": "CCNA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43303-1",
                "protein_name": "Centriolar coiled-coil protein of 110 kDa",
                "gene_name": "CCP110",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P14735-1",
                "protein_name": "Insulin-degrading enzyme",
                "gene_name": "IDE",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NQC7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase CYLD",
                "gene_name": "CYLD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95786-1",
                "protein_name": "Antiviral innate immune response receptor RIG-I",
                "gene_name": "DDX58; RIGI",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y265-1",
                "protein_name": "RuvB-like 1",
                "gene_name": "RUVBL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK80-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 21",
                "gene_name": "USP21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZL9-1",
                "protein_name": "Methionine adenosyltransferase 2 subunit beta",
                "gene_name": "MAT2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92830-1",
                "protein_name": "Histone acetyltransferase KAT2A",
                "gene_name": "KAT2A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43255-1",
                "protein_name": "E3 ubiquitin-protein ligase SIAH2",
                "gene_name": "SIAH2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43318-1",
                "protein_name": "Mitogen-activated protein kinase kinase kinase 7",
                "gene_name": "MAP3K7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
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    {
        "title": "Sonic Hedgehog dependent phosphorylation by CK1alpha and GRK2 is required for ciliary accumulation and activation of smoothened.",
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        "authors": "Chen Y, Sasai N, Ma G, Yue T, Jia J, Briscoe J, Jiang J",
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                "name": "Homo sapiens",
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        ],
        "record_id": "pubmed.21695114",
        "abstract": "",
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    {
        "title": "COMMD1 (copper metabolism MURR1 domain-containing protein 1) regulates Cullin RING ligases by preventing CAND1 (Cullin-associated Nedd8-dissociated protein 1) binding.",
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                "protein_name": "Mitochondrial ubiquitin ligase activator of NFKB 1",
                "gene_name": "MUL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00231-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 11",
                "gene_name": "PSMD11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16186-1",
                "protein_name": "Proteasomal ubiquitin receptor ADRM1",
                "gene_name": "ADRM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2K6-1",
                "protein_name": "Kelch-like protein 42",
                "gene_name": "KLHL42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BM1-1",
                "protein_name": "Ankyrin repeat domain-containing protein 9",
                "gene_name": "ANKRD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2M5-1",
                "protein_name": "Kelch-like protein 20",
                "gene_name": "KLHL20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNS2-1",
                "protein_name": "COP9 signalosome complex subunit 3",
                "gene_name": "COPS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93034-1",
                "protein_name": "Cullin-5",
                "gene_name": "CUL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13616-1",
                "protein_name": "Cullin-1",
                "gene_name": "CUL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H672-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 7",
                "gene_name": "ASB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96Q27-2",
                "protein_name": "Ankyrin repeat and SOCS box protein 2",
                "gene_name": "ASB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y574-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 4",
                "gene_name": "ASB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NK59-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 14",
                "gene_name": "ASB14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBF6-1",
                "protein_name": "RING-box protein 2",
                "gene_name": "RNF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15291-1",
                "protein_name": "Retinoblastoma-binding protein 5",
                "gene_name": "RBBP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZVZ8-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 18",
                "gene_name": "ASB18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAT6-1",
                "protein_name": "Nuclear protein localization protein 4 homolog",
                "gene_name": "NPLOC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92890-2",
                "protein_name": "Ubiquitin recognition factor in ER-associated degradation protein 1",
                "gene_name": "UFD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41002-1",
                "protein_name": "Cyclin-F",
                "gene_name": "CCNF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05516-1",
                "protein_name": "Zinc finger and BTB domain-containing protein 16",
                "gene_name": "ZBTB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15369-1",
                "protein_name": "Elongin-C",
                "gene_name": "ELOC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWT3-1",
                "protein_name": "Cullin-9",
                "gene_name": "CUL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBC4-1",
                "protein_name": "NEDD8-activating enzyme E1 catalytic subunit",
                "gene_name": "UBA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13216-1",
                "protein_name": "DNA excision repair protein ERCC-8",
                "gene_name": "ERCC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16576-1",
                "protein_name": "Histone-binding protein RBBP7",
                "gene_name": "RBBP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NI29-1",
                "protein_name": "F-box only protein 27",
                "gene_name": "FBXO27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P050-1",
                "protein_name": "F-box and leucine-rich protein 22",
                "gene_name": "FBXL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEZ5-1",
                "protein_name": "F-box only protein 22",
                "gene_name": "FBXO22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRD1-1",
                "protein_name": "F-box only protein 6",
                "gene_name": "FBXO6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX1-3",
                "protein_name": "F-box/WD repeat-containing protein 9",
                "gene_name": "FBXW9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N3Y1-1",
                "protein_name": "F-box/WD repeat-containing protein 8",
                "gene_name": "FBXW8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK97-1",
                "protein_name": "F-box only protein 9",
                "gene_name": "FBXO9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA1-1",
                "protein_name": "F-box/LRR-repeat protein 5",
                "gene_name": "FBXL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA2-1",
                "protein_name": "F-box/LRR-repeat protein 4",
                "gene_name": "FBXL4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCT2-1",
                "protein_name": "F-box/LRR-repeat protein 19",
                "gene_name": "FBXL19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N461-1",
                "protein_name": "F-box/LRR-repeat protein 16",
                "gene_name": "FBXL16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBW8-1",
                "protein_name": "COP9 signalosome complex subunit 7a",
                "gene_name": "COPS7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99627-1",
                "protein_name": "COP9 signalosome complex subunit 8",
                "gene_name": "COPS8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75147-3",
                "protein_name": "Obscurin-like protein 1",
                "gene_name": "OBSL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSE2-1",
                "protein_name": "Cytokine-inducible SH2-containing protein",
                "gene_name": "CISH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BR09-1",
                "protein_name": "Neuralized-like protein 2",
                "gene_name": "NEURL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15392-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 5",
                "gene_name": "BIRC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14508-1",
                "protein_name": "Suppressor of cytokine signaling 2",
                "gene_name": "SOCS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16531-1",
                "protein_name": "DNA damage-binding protein 1",
                "gene_name": "DDB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96GG9-1",
                "protein_name": "DCN1-like protein 1",
                "gene_name": "DCUN1D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99814-1",
                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N668-1",
                "protein_name": "COMM domain-containing protein 1",
                "gene_name": "COMMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBI1-1",
                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
                "gene_name": "COPS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4G1-1",
                "protein_name": "COMM domain-containing protein 6",
                "gene_name": "COMMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
                "gene_name": "COMMD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6G5-1",
                "protein_name": "COMM domain-containing protein 10",
                "gene_name": "COMMD10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0W5-1",
                "protein_name": "Coiled-coil domain-containing protein 8",
                "gene_name": "CCDC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
                "gene_name": "COPS4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62877-1",
                "protein_name": "E3 ubiquitin-protein ligase RBX1",
                "gene_name": "RBX1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15843-1",
                "protein_name": "Ubiquitin-like protein NEDD8",
                "gene_name": "NEDD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61081-1",
                "protein_name": "NEDD8-conjugating enzyme Ubc12",
                "gene_name": "UBE2M",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86V97-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 6",
                "gene_name": "KBTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WVZ9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 7",
                "gene_name": "KBTBD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRJ4-1",
                "protein_name": "Tubby-related protein 4",
                "gene_name": "TULP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61964-1",
                "protein_name": "WD repeat-containing protein 5",
                "gene_name": "WDR5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P55072-1",
                "protein_name": "Transitional endoplasmic reticulum ATPase",
                "gene_name": "VCP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13618-1",
                "protein_name": "Cullin-3",
                "gene_name": "CUL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NHY2-1",
                "protein_name": "E3 ubiquitin-protein ligase COP1",
                "gene_name": "COP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L5N1-1",
                "protein_name": "COP9 signalosome complex subunit 6",
                "gene_name": "COPS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
                "gene_name": "VHL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5TAQ9-1",
                "protein_name": "DDB1- and CUL4-associated factor 8",
                "gene_name": "DCAF8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96BD6-1",
                "protein_name": "SPRY domain-containing SOCS box protein 1",
                "gene_name": "SPSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5JTC6-1",
                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
                "gene_name": "CCDC22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NC69-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD6",
                "gene_name": "KCTD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14544-1",
                "protein_name": "Suppressor of cytokine signaling 6",
                "gene_name": "SOCS6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
                "gene_name": "FBXW11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWE4-1",
                "protein_name": "DCN1-like protein 3",
                "gene_name": "DCUN1D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92905-1",
                "protein_name": "COP9 signalosome complex subunit 5",
                "gene_name": "COPS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13617-1",
                "protein_name": "Cullin-2",
                "gene_name": "CUL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13619-1",
                "protein_name": "Cullin-4A",
                "gene_name": "CUL4A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VP6-1",
                "protein_name": "Cullin-associated NEDD8-dissociated protein 1",
                "gene_name": "CAND1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62837-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D2",
                "gene_name": "UBE2D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13620-2",
                "protein_name": "Cullin-4B",
                "gene_name": "CUL4B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0C5-1",
                "protein_name": "BTB/POZ domain-containing protein 1",
                "gene_name": "BTBD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXF7-1",
                "protein_name": "DDB1- and CUL4-associated factor 16",
                "gene_name": "DCAF16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2N7-1",
                "protein_name": "Hypoxia-inducible factor 3-alpha",
                "gene_name": "HIF3A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NCQ5-1",
                "protein_name": "F-box only protein 15",
                "gene_name": "FBXO15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK96-1",
                "protein_name": "F-box only protein 10",
                "gene_name": "FBXO10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB52-1",
                "protein_name": "F-box only protein 30",
                "gene_name": "FBXO30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JP0-1",
                "protein_name": "Protein fem-1 homolog C",
                "gene_name": "FEM1C",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UH90-1",
                "protein_name": "F-box only protein 40",
                "gene_name": "FBXO40",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969M7-1",
                "protein_name": "NEDD8-conjugating enzyme UBE2F",
                "gene_name": "UBE2F-SCLY; UBE2F",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96LD8-1",
                "protein_name": "Sentrin-specific protease 8",
                "gene_name": "SENP8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13564-1",
                "protein_name": "NEDD8-activating enzyme E1 regulatory subunit",
                "gene_name": "NAE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95198-1",
                "protein_name": "Kelch-like protein 2",
                "gene_name": "KLHL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P38936-1",
                "protein_name": "Cyclin-dependent kinase inhibitor 1",
                "gene_name": "CDKN1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NXK8-1",
                "protein_name": "F-box/LRR-repeat protein 12",
                "gene_name": "FBXL12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT8-1",
                "protein_name": "F-box/WD repeat-containing protein 2",
                "gene_name": "FBXW2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEB1-1",
                "protein_name": "DDB1- and CUL4-associated factor 11",
                "gene_name": "DCAF11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TB72-1",
                "protein_name": "Pumilio homolog 2",
                "gene_name": "PUM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BTE7-1",
                "protein_name": "DCN1-like protein 5",
                "gene_name": "DCUN1D5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q58WW2-1",
                "protein_name": "DDB1- and CUL4-associated factor 6",
                "gene_name": "DCAF6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PH85-1",
                "protein_name": "DCN1-like protein 2",
                "gene_name": "DCUN1D2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92564-1",
                "protein_name": "DCN1-like protein 4",
                "gene_name": "DCUN1D4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96JK2-1",
                "protein_name": "DDB1- and CUL4-associated factor 5",
                "gene_name": "DCAF5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NZJ0-1",
                "protein_name": "Denticleless protein homolog",
                "gene_name": "DTL",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NV06-1",
                "protein_name": "DDB1- and CUL4-associated factor 13",
                "gene_name": "DCAF13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NY33-1",
                "protein_name": "Dipeptidyl peptidase 3",
                "gene_name": "DPP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94952-2",
                "protein_name": "F-box only protein 21",
                "gene_name": "FBXO21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TF61-1",
                "protein_name": "F-box only protein 41",
                "gene_name": "FBXO41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BSK4-1",
                "protein_name": "Protein fem-1 homolog A",
                "gene_name": "FEM1A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96IG2-1",
                "protein_name": "F-box/LRR-repeat protein 20",
                "gene_name": "FBXL20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK73-1",
                "protein_name": "Protein fem-1 homolog B",
                "gene_name": "FEM1B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NFY9-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 8",
                "gene_name": "KBTBD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75159-1",
                "protein_name": "Suppressor of cytokine signaling 5",
                "gene_name": "SOCS5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6X9E4-1",
                "protein_name": "F-box/WD repeat-containing protein 12",
                "gene_name": "FBXW12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PJ21-1",
                "protein_name": "SPRY domain-containing SOCS box protein 3",
                "gene_name": "SPSB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XX13-1",
                "protein_name": "F-box/WD repeat-containing protein 10",
                "gene_name": "FBXW10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P38398-1",
                "protein_name": "Breast cancer type 1 susceptibility protein",
                "gene_name": "BRCA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
                "protein_name": "Polyubiquitin-C",
                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14145-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
                "gene_name": "KEAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P63208-1",
                "protein_name": "S-phase kinase-associated protein 1",
                "gene_name": "SKP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT5-1",
                "protein_name": "F-box only protein 4",
                "gene_name": "FBXO4",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
                    {
                        "database": "UniProtKB",
                        "id": "O14818",
                        "url": "https://www.uniprot.org/uniprotkb/O14818"
                    }
                ],
                "common_name": "Human",
                "glygen_name": "Human",
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        ],
        "record_id": "pubmed.21801010",
        "abstract": "",
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    {
        "title": "Activation of interleukin-6 gene expression through the NF-kappa B transcription factor.",
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        "authors": "Libermann TA, Baltimore D",
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    {
        "title": "The USP19 deubiquitinase regulates the stability of c-IAP1 and c-IAP2.",
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        "date": "2011",
        "authors": "Mei Y, Hahn AA, Hu S, Yang X",
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                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y256-1",
                "protein_name": "CAAX prenyl protease 2",
                "gene_name": "RCE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NTX7-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF146",
                "gene_name": "RNF146",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95760-1",
                "protein_name": "Interleukin-33",
                "gene_name": "IL33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04908-1",
                "protein_name": "Histone H2A type 1-B/E",
                "gene_name": "H2AC4; H2AC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06899-1",
                "protein_name": "Histone H2B type 1-J",
                "gene_name": "H2BC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20671-1",
                "protein_name": "Histone H2A type 1-D",
                "gene_name": "H2AC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16777-1",
                "protein_name": "Histone H2A type 2-C",
                "gene_name": "H2AC20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6FI13-1",
                "protein_name": "Histone H2A type 2-A",
                "gene_name": "H2AC18; H2AC19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L7L0-1",
                "protein_name": "Histone H2A type 3",
                "gene_name": "H2AC25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IUE6-1",
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                "tax_name": "Human"
            },
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                "tax_name": "Human"
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                "protein_name": "Endothelial PAS domain-containing protein 1",
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            },
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                "uniprot_canonical_ac": "Q9BW61-1",
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                "protein_name": "26S proteasome regulatory subunit 10B",
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                "protein_name": "COP9 signalosome complex subunit 2",
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                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
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                "uniprot_canonical_ac": "Q9H0W5-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9NX08-1",
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                "protein_name": "COMM domain-containing protein 5",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
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                "uniprot_canonical_ac": "Q5QP82-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "O60662-1",
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                "tax_name": "Human"
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                "protein_name": "Kelch-like protein 9",
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                "protein_name": "LIM domain only protein 7",
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                "protein_name": "Kelch-like protein 11",
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                "protein_name": "Proteasome subunit beta type-2",
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                "protein_name": "Ubiquitin D",
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                "protein_name": "Nuclear factor erythroid 2-related factor 2",
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                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
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                "protein_name": "E3 ubiquitin-protein ligase RBX1",
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                "protein_name": "WD repeat-containing protein 5",
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                "protein_name": "Transitional endoplasmic reticulum ATPase",
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                "protein_name": "E3 ubiquitin-protein ligase COP1",
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                "uniprot_canonical_ac": "P40337-1",
                "protein_name": "von Hippel-Lindau disease tumor suppressor",
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                "uniprot_canonical_ac": "Q5TAQ9-1",
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                "tax_name": "Human"
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                "protein_name": "SPRY domain-containing SOCS box protein 1",
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            {
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                "protein_name": "APC membrane recruitment protein 1",
                "gene_name": "AMER1",
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                "protein_name": "26S proteasome regulatory subunit 6A",
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                "uniprot_canonical_ac": "Q99619-1",
                "protein_name": "SPRY domain-containing SOCS box protein 2",
                "gene_name": "SPSB2",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "O60826-1",
                "protein_name": "Coiled-coil domain-containing protein 22",
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                "uniprot_canonical_ac": "Q8NC69-1",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9Y297-1",
                "protein_name": "F-box/WD repeat-containing protein 1A",
                "gene_name": "BTRC",
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                "protein_name": "Suppressor of cytokine signaling 6",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q9UKB1-1",
                "protein_name": "F-box/WD repeat-containing protein 11",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
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                "tax_name": "Human"
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                "uniprot_canonical_ac": "Q8IWE4-1",
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                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q9UH77-1",
                "protein_name": "Kelch-like protein 3",
                "gene_name": "KLHL3",
                "tax_name": "Human"
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            {
                "uniprot_canonical_ac": "Q969P5-1",
                "protein_name": "F-box only protein 32",
                "gene_name": "FBXO32",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y3I1-1",
                "protein_name": "F-box only protein 7",
                "gene_name": "FBXO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H469-1",
                "protein_name": "F-box/LRR-repeat protein 15",
                "gene_name": "FBXL15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96CD0-1",
                "protein_name": "F-box/LRR-repeat protein 8",
                "gene_name": "FBXL8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEE6-1",
                "protein_name": "F-box and leucine-rich repeat protein 13",
                "gene_name": "FBXL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT7-1",
                "protein_name": "F-box/LRR-repeat protein 3",
                "gene_name": "FBXL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96EF6-1",
                "protein_name": "F-box only protein 17",
                "gene_name": "FBXO17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK22-1",
                "protein_name": "F-box only protein 2",
                "gene_name": "FBXO2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P57775-1",
                "protein_name": "F-box/WD repeat-containing protein 4",
                "gene_name": "FBXW4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N1E6-1",
                "protein_name": "F-box/LRR-repeat protein 14",
                "gene_name": "FBXL14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96ME1-4",
                "protein_name": "F-box/LRR-repeat protein 18",
                "gene_name": "FBXL18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJT9-1",
                "protein_name": "F-box/LRR-repeat protein 7",
                "gene_name": "FBXL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKT6-1",
                "protein_name": "Putative F-box/LRR-repeat protein 21",
                "gene_name": "FBXL21P",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14543-1",
                "protein_name": "Suppressor of cytokine signaling 3",
                "gene_name": "SOCS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N5D0-1",
                "protein_name": "WD and tetratricopeptide repeats protein 1",
                "gene_name": "WDTC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13501-1",
                "protein_name": "Sequestosome-1",
                "gene_name": "SQSTM1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969U6-1",
                "protein_name": "F-box/WD repeat-containing protein 5",
                "gene_name": "FBXW5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86XK2-1",
                "protein_name": "F-box only protein 11",
                "gene_name": "FBXO11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86YC2-1",
                "protein_name": "Partner and localizer of BRCA2",
                "gene_name": "PALB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H4M3-1",
                "protein_name": "F-box only protein 44",
                "gene_name": "FBXO44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KE9-3",
                "protein_name": "BTB/POZ domain-containing protein 6",
                "gene_name": "BTBD6",
                "tax_name": "Human"
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    {
        "title": "The antagonistic action of B56-containing protein phosphatase 2As and casein kinase 2 controls the phosphorylation and Gli turnover function of Daz interacting protein 1.",
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                "uniprot_canonical_ac": "Q13616-1",
                "protein_name": "Cullin-1",
                "gene_name": "CUL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H672-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 7",
                "gene_name": "ASB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96Q27-2",
                "protein_name": "Ankyrin repeat and SOCS box protein 2",
                "gene_name": "ASB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y574-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 4",
                "gene_name": "ASB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NK59-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 14",
                "gene_name": "ASB14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBF6-1",
                "protein_name": "RING-box protein 2",
                "gene_name": "RNF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15291-1",
                "protein_name": "Retinoblastoma-binding protein 5",
                "gene_name": "RBBP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6ZVZ8-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 18",
                "gene_name": "ASB18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAT6-1",
                "protein_name": "Nuclear protein localization protein 4 homolog",
                "gene_name": "NPLOC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92890-2",
                "protein_name": "Ubiquitin recognition factor in ER-associated degradation protein 1",
                "gene_name": "UFD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P41002-1",
                "protein_name": "Cyclin-F",
                "gene_name": "CCNF",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q05516-1",
                "protein_name": "Zinc finger and BTB domain-containing protein 16",
                "gene_name": "ZBTB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15369-1",
                "protein_name": "Elongin-C",
                "gene_name": "ELOC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IWT3-1",
                "protein_name": "Cullin-9",
                "gene_name": "CUL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBC4-1",
                "protein_name": "NEDD8-activating enzyme E1 catalytic subunit",
                "gene_name": "UBA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13216-1",
                "protein_name": "DNA excision repair protein ERCC-8",
                "gene_name": "ERCC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62195-1",
                "protein_name": "26S proteasome regulatory subunit 8",
                "gene_name": "PSMC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16576-1",
                "protein_name": "Histone-binding protein RBBP7",
                "gene_name": "RBBP7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NI29-1",
                "protein_name": "F-box only protein 27",
                "gene_name": "FBXO27",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6P050-1",
                "protein_name": "F-box and leucine-rich protein 22",
                "gene_name": "FBXL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8NEZ5-1",
                "protein_name": "F-box only protein 22",
                "gene_name": "FBXO22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NRD1-1",
                "protein_name": "F-box only protein 6",
                "gene_name": "FBXO6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX1-3",
                "protein_name": "F-box/WD repeat-containing protein 9",
                "gene_name": "FBXW9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N3Y1-1",
                "protein_name": "F-box/WD repeat-containing protein 8",
                "gene_name": "FBXW8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UK97-1",
                "protein_name": "F-box only protein 9",
                "gene_name": "FBXO9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA1-1",
                "protein_name": "F-box/LRR-repeat protein 5",
                "gene_name": "FBXL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UKA2-1",
                "protein_name": "F-box/LRR-repeat protein 4",
                "gene_name": "FBXL4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6PCT2-1",
                "protein_name": "F-box/LRR-repeat protein 19",
                "gene_name": "FBXL19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N461-1",
                "protein_name": "F-box/LRR-repeat protein 16",
                "gene_name": "FBXL16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25789-1",
                "protein_name": "Proteasome subunit alpha type-4",
                "gene_name": "PSMA4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2C0-1",
                "protein_name": "Gigaxonin",
                "gene_name": "GAN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15345-2",
                "protein_name": "Leucine-rich repeat-containing protein 41",
                "gene_name": "LRRC41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96MP8-1",
                "protein_name": "BTB/POZ domain-containing protein KCTD7",
                "gene_name": "KCTD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JR72-1",
                "protein_name": "Kelch repeat and BTB domain-containing protein 13",
                "gene_name": "KBTBD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0H3-1",
                "protein_name": "Kelch-like protein 25",
                "gene_name": "KLHL25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UJP4-1",
                "protein_name": "Kelch-like protein 21",
                "gene_name": "KLHL21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96L50-1",
                "protein_name": "Leucine-rich repeat protein 1",
                "gene_name": "LRR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62191-1",
                "protein_name": "26S proteasome regulatory subunit 4",
                "gene_name": "PSMC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBW8-1",
                "protein_name": "COP9 signalosome complex subunit 7a",
                "gene_name": "COPS7A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99627-1",
                "protein_name": "COP9 signalosome complex subunit 8",
                "gene_name": "COPS8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75147-3",
                "protein_name": "Obscurin-like protein 1",
                "gene_name": "OBSL1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49720-1",
                "protein_name": "Proteasome subunit beta type-3",
                "gene_name": "PSMB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99460-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 1",
                "gene_name": "PSMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UNM6-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 13",
                "gene_name": "PSMD13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51665-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 7",
                "gene_name": "PSMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NSE2-1",
                "protein_name": "Cytokine-inducible SH2-containing protein",
                "gene_name": "CISH",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13309-1",
                "protein_name": "S-phase kinase-associated protein 2",
                "gene_name": "SKP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12395-1",
                "protein_name": "Defective in cullin neddylation protein 1",
                "gene_name": "DCN1",
                "tax_name": "Baker's yeast"
            },
            {
                "uniprot_canonical_ac": "Q9BR09-1",
                "protein_name": "Neuralized-like protein 2",
                "gene_name": "NEURL2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28074-1",
                "protein_name": "Proteasome subunit beta type-5",
                "gene_name": "PSMB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P35998-1",
                "protein_name": "26S proteasome regulatory subunit 7",
                "gene_name": "PSMC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P43686-1",
                "protein_name": "26S proteasome regulatory subunit 6B",
                "gene_name": "PSMC4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99436-1",
                "protein_name": "Proteasome subunit beta type-7",
                "gene_name": "PSMB7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15392-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 5",
                "gene_name": "BIRC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XUX0-1",
                "protein_name": "F-box only protein 31",
                "gene_name": "FBXO31",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15370-1",
                "protein_name": "Elongin-B",
                "gene_name": "ELOB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61077-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D3",
                "gene_name": "UBE2D3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51668-1",
                "protein_name": "Ubiquitin-conjugating enzyme E2 D1",
                "gene_name": "UBE2D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14508-1",
                "protein_name": "Suppressor of cytokine signaling 2",
                "gene_name": "SOCS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16531-1",
                "protein_name": "DNA damage-binding protein 1",
                "gene_name": "DDB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXI3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 10",
                "gene_name": "ASB10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13200-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 2",
                "gene_name": "PSMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96GG9-1",
                "protein_name": "DCN1-like protein 1",
                "gene_name": "DCUN1D1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK1-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 15",
                "gene_name": "ASB15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H765-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 8",
                "gene_name": "ASB8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y576-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 1",
                "gene_name": "ASB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96NS5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 16",
                "gene_name": "ASB16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXH4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 11",
                "gene_name": "ASB11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXJ9-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 17",
                "gene_name": "ASB17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK3-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 13",
                "gene_name": "ASB13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WXK4-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 12",
                "gene_name": "ASB12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NWX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 6",
                "gene_name": "ASB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y575-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 3",
                "gene_name": "ASB3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99814-1",
                "protein_name": "Endothelial PAS domain-containing protein 1",
                "gene_name": "EPAS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BW61-1",
                "protein_name": "DET1- and DDB1-associated protein 1",
                "gene_name": "DDA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N668-1",
                "protein_name": "COMM domain-containing protein 1",
                "gene_name": "COMMD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62333-1",
                "protein_name": "26S proteasome regulatory subunit 10B",
                "gene_name": "PSMC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWX0-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 5",
                "gene_name": "ASB5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96DX5-1",
                "protein_name": "Ankyrin repeat and SOCS box protein 9",
                "gene_name": "ASB9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UBI1-1",
                "protein_name": "COMM domain-containing protein 3",
                "gene_name": "COMMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61201-1",
                "protein_name": "COP9 signalosome complex subunit 2",
                "gene_name": "COPS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7Z4G1-1",
                "protein_name": "COMM domain-containing protein 6",
                "gene_name": "COMMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0A8-1",
                "protein_name": "COMM domain-containing protein 4",
                "gene_name": "COMMD4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6G5-1",
                "protein_name": "COMM domain-containing protein 10",
                "gene_name": "COMMD10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O43242-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 3",
                "gene_name": "PSMD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0W5-1",
                "protein_name": "Coiled-coil domain-containing protein 8",
                "gene_name": "CCDC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86X83-1",
                "protein_name": "COMM domain-containing protein 2",
                "gene_name": "COMMD2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86VX2-1",
                "protein_name": "COMM domain-containing protein 7",
                "gene_name": "COMMD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P000-1",
                "protein_name": "COMM domain-containing protein 9",
                "gene_name": "COMMD9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q969H0-1",
                "protein_name": "F-box/WD repeat-containing protein 7",
                "gene_name": "FBXW7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NX08-1",
                "protein_name": "COMM domain-containing protein 8",
                "gene_name": "COMMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9GZQ3-1",
                "protein_name": "COMM domain-containing protein 5",
                "gene_name": "COMMD5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5H9S7-1",
                "protein_name": "DDB1- and CUL4-associated factor 17",
                "gene_name": "DCAF17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P61962-1",
                "protein_name": "DDB1- and CUL4-associated factor 7",
                "gene_name": "DCAF7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WV16-1",
                "protein_name": "DDB1- and CUL4-associated factor 4",
                "gene_name": "DCAF4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q53GT1-1",
                "protein_name": "Kelch-like protein 22",
                "gene_name": "KLHL22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QP82-1",
                "protein_name": "DDB1- and CUL4-associated factor 10",
                "gene_name": "DCAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60662-1",
                "protein_name": "Kelch-like protein 41",
                "gene_name": "KLHL41",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2J3-1",
                "protein_name": "Kelch-like protein 9",
                "gene_name": "KLHL9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8WWI1-1",
                "protein_name": "LIM domain only protein 7",
                "gene_name": "LMO7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NVR0-1",
                "protein_name": "Kelch-like protein 11",
                "gene_name": "KLHL11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9P2N7-1",
                "protein_name": "Kelch-like protein 13",
                "gene_name": "KLHL13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49721-1",
                "protein_name": "Proteasome subunit beta type-2",
                "gene_name": "PSMB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20618-1",
                "protein_name": "Proteasome subunit beta type-1",
                "gene_name": "PSMB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15205-1",
                "protein_name": "Ubiquitin D",
                "gene_name": "UBD",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16236-1",
                "protein_name": "Nuclear factor erythroid 2-related factor 2",
                "gene_name": "NFE2L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96PQ7-1",
                "protein_name": "Kelch-like protein 5",
                "gene_name": "KLHL5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P15374-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase isozyme L3",
                "gene_name": "UCHL3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NYS7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 2",
                "gene_name": "WSB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I7-1",
                "protein_name": "WD repeat and SOCS box-containing protein 1",
                "gene_name": "WSB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9Q2-1",
                "protein_name": "COP9 signalosome complex subunit 7b",
                "gene_name": "COPS7B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14999-1",
                "protein_name": "Cullin-7",
                "gene_name": "CUL7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94888-1",
                "protein_name": "UBX domain-containing protein 7",
                "gene_name": "UBXN7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13098-4",
                "protein_name": "COP9 signalosome complex subunit 1",
                "gene_name": "GPS1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BT78-1",
                "protein_name": "COP9 signalosome complex subunit 4",
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                "uniprot_canonical_ac": "Q9NRJ4-1",
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            },
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            {
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            {
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            {
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            {
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            {
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                "protein_name": "F-box only protein 4",
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        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                        "database": "UniProtKB",
                        "id": "O14818",
                        "url": "https://www.uniprot.org/uniprotkb/O14818"
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                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
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        ],
        "record_id": "pubmed.21940857",
        "abstract": "",
        "glycosylation": [],
        "mutagenesis": [],
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        "phosphorylation": [],
        "glycation": [],
        "section_stats": [
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    {
        "title": "Beclin1 controls the levels of p53 by regulating the deubiquitination activity of USP10 and USP13.",
        "journal": "Cell",
        "date": "2011",
        "authors": "Liu J, Xia H, Kim M, Xu L, Li Y, Zhang L, Cai Y, Norberg HV, Zhang T, Furuya T, Jin M, Zhu Z, Wang H, Yu J, Li Y, Hao Y, Choi A, Ke H, Ma D, Yuan J",
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            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y256-1",
                "protein_name": "CAAX prenyl protease 2",
                "gene_name": "RCE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NTX7-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF146",
                "gene_name": "RNF146",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95760-1",
                "protein_name": "Interleukin-33",
                "gene_name": "IL33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04908-1",
                "protein_name": "Histone H2A type 1-B/E",
                "gene_name": "H2AC4; H2AC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06899-1",
                "protein_name": "Histone H2B type 1-J",
                "gene_name": "H2BC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20671-1",
                "protein_name": "Histone H2A type 1-D",
                "gene_name": "H2AC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16777-1",
                "protein_name": "Histone H2A type 2-C",
                "gene_name": "H2AC20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6FI13-1",
                "protein_name": "Histone H2A type 2-A",
                "gene_name": "H2AC18; H2AC19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L7L0-1",
                "protein_name": "Histone H2A type 3",
                "gene_name": "H2AC25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IUE6-1",
                "protein_name": "Histone H2A type 2-B",
                "gene_name": "H2AC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8N257-1",
                "protein_name": "Histone H2B type 3-B",
                "gene_name": "H2BC26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96QV6-1",
                "protein_name": "Histone H2A type 1-A",
                "gene_name": "H2AC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99877-1",
                "protein_name": "Histone H2B type 1-N",
                "gene_name": "H2BC15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99878-1",
                "protein_name": "Histone H2A type 1-J",
                "gene_name": "H2AC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99880-1",
                "protein_name": "Histone H2B type 1-L",
                "gene_name": "H2BC13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92995-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 13",
                "gene_name": "USP13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94966-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 19",
                "gene_name": "USP19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y5T5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 16",
                "gene_name": "USP16",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPU5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 24",
                "gene_name": "USP24",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TAF3-1",
                "protein_name": "WD repeat-containing protein 48",
                "gene_name": "WDR48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12933-1",
                "protein_name": "TNF receptor-associated factor 2",
                "gene_name": "TRAF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6K9-1",
                "protein_name": "NF-kappa-B essential modulator",
                "gene_name": "IKBKG",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P30304-1",
                "protein_name": "M-phase inducer phosphatase 1",
                "gene_name": "CDC25A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15151-1",
                "protein_name": "Protein Mdm4",
                "gene_name": "MDM4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13107-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 4",
                "gene_name": "USP4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UPT9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 22",
                "gene_name": "USP22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O14964-1",
                "protein_name": "Hepatocyte growth factor-regulated tyrosine kinase substrate",
                "gene_name": "HGS",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG48-1",
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                "gene_name": "UBC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14145-1",
                "protein_name": "Kelch-like ECH-associated protein 1",
                "gene_name": "KEAP1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q00987-1",
                "protein_name": "E3 ubiquitin-protein ligase Mdm2",
                "gene_name": "MDM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75886-1",
                "protein_name": "Signal transducing adapter molecule 2",
                "gene_name": "STAM2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75604-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 2",
                "gene_name": "USP2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P10275-1",
                "protein_name": "Androgen receptor",
                "gene_name": "AR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04637-1",
                "protein_name": "Cellular tumor antigen p53",
                "gene_name": "TP53",
                "tax_name": "Human"
            }
        ],
        "species": [
            {
                "name": "Homo sapiens",
                "taxid": 9606,
                "evidence": [
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                        "id": "O14818",
                        "url": "https://www.uniprot.org/uniprotkb/O14818"
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                ],
                "common_name": "Human",
                "glygen_name": "Human",
                "reference_species": "Homo sapiens [9606]"
            }
        ],
        "mutagenesis": [
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                "start_pos": 424,
                "end_pos": 424,
                "sequence_org": "C",
                "sequence_mut": "A",
                "comment": "Abolishes deubiquitinating activity and ability to deubiquitinate 40S ribosomal proteins.",
                "evidence": [
                    {
                        "database": "UniProtKB",
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                        "url": "https://www.uniprot.org/uniprotkb/Q14694"
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                    {
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                    {
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                    {
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/19398555"
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                    {
                        "database": "PubMed",
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/31981475"
                    },
                    {
                        "database": "PubMed",
                        "id": "37582970",
                        "url": "https://pubmed.ncbi.nlm.nih.gov/37582970"
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                ],
                "uniprot_canonical_ac": "Q14694-1"
            },
            {
                "start_pos": 424,
                "end_pos": 424,
                "sequence_org": "C",
                "sequence_mut": "S",
                "comment": "Abolishes deubiquitinating activity and ability to deubiquitinate 40S ribosomal proteins.",
                "evidence": [
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                        "database": "UniProtKB",
                        "id": "Q14694",
                        "url": "https://www.uniprot.org/uniprotkb/Q14694"
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                    {
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/21962518"
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                    {
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/24845384"
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                    {
                        "database": "PubMed",
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/11439350"
                    },
                    {
                        "database": "PubMed",
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                        "url": "https://pubmed.ncbi.nlm.nih.gov/19398555"
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                    {
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        "title": "Protein kinase A acts at the basal body of the primary cilium to prevent Gli2 activation and ventralization of the mouse neural tube.",
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    {
        "title": "The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations.",
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        "authors": "Huang G, Zhao X, Wang L, Elf S, Xu H, Zhao X, Sashida G, Zhang Y, Liu Y, Lee J, Menendez S, Yang Y, Yan X, Zhang P, Tenen DG, Osato M, Hsieh JJ, Nimer SD",
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        "authors": "Xiao N, Li H, Luo J, Wang R, Chen H, Chen J, Wang P",
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            {
                "uniprot_canonical_ac": "Q8IXI2-1",
                "protein_name": "Mitochondrial Rho GTPase 1",
                "gene_name": "RHOT1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P54578-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 14",
                "gene_name": "USP14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86TJ2-1",
                "protein_name": "Transcriptional adapter 2-beta",
                "gene_name": "TADA2B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q92466-1",
                "protein_name": "DNA damage-binding protein 2",
                "gene_name": "DDB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28070-1",
                "protein_name": "Proteasome subunit beta type-4",
                "gene_name": "PSMB4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UMW8-1",
                "protein_name": "Ubl carboxyl-terminal hydrolase 18",
                "gene_name": "USP18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JJH3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 10",
                "gene_name": "USP17L10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW7-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4",
                "gene_name": "USP17L4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45880-3",
                "protein_name": "Non-selective voltage-gated ion channel VDAC2",
                "gene_name": "VDAC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06746-1",
                "protein_name": "DNA polymerase beta",
                "gene_name": "POLB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P07550-1",
                "protein_name": "Beta-2 adrenergic receptor",
                "gene_name": "ADRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C0S8-1",
                "protein_name": "Histone H2A type 1",
                "gene_name": "H2AC11; H2AC13; H2AC15; H2AC16; H2AC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P36897-1",
                "protein_name": "TGF-beta receptor type-1",
                "gene_name": "TGFBR1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15105-1",
                "protein_name": "SMAD family member 7",
                "gene_name": "SMAD7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P32121-1",
                "protein_name": "Beta-arrestin-2",
                "gene_name": "ARRB2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H2K2-1",
                "protein_name": "Poly [ADP-ribose] polymerase tankyrase-2",
                "gene_name": "TNKS2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25786-1",
                "protein_name": "Proteasome subunit alpha type-1",
                "gene_name": "PSMA1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P49407-1",
                "protein_name": "Beta-arrestin-1",
                "gene_name": "ARRB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P98177-1",
                "protein_name": "Forkhead box protein O4",
                "gene_name": "FOXO4",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P17980-1",
                "protein_name": "26S proteasome regulatory subunit 6A",
                "gene_name": "PSMC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y2T1-1",
                "protein_name": "Axin-2",
                "gene_name": "AXIN2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23771-1",
                "protein_name": "Trans-acting T-cell-specific transcription factor GATA-3",
                "gene_name": "GATA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16778-1",
                "protein_name": "Histone H2B type 2-E",
                "gene_name": "H2BC21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O15169-1",
                "protein_name": "Axin-1",
                "gene_name": "AXIN1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62807-1",
                "protein_name": "Histone H2B type 1-C/E/F/G/I",
                "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P84022-1",
                "protein_name": "SMAD family member 3",
                "gene_name": "SMAD3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15797-1",
                "protein_name": "SMAD family member 1",
                "gene_name": "SMAD1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25788-1",
                "protein_name": "Proteasome subunit alpha type-3",
                "gene_name": "PSMA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q14694-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 10",
                "gene_name": "USP10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAU4-1",
                "protein_name": "E3 ubiquitin-protein ligase SMURF2",
                "gene_name": "SMURF2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H0E7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 44",
                "gene_name": "USP44",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86UV5-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 48",
                "gene_name": "USP48",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RBQ6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 17",
                "gene_name": "USP17L17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ3-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 30",
                "gene_name": "USP30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TEY7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 33",
                "gene_name": "USP33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RCP7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 19",
                "gene_name": "USP17L19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JLJ4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 13",
                "gene_name": "USP17L13",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RJB6-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 20",
                "gene_name": "USP17L20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15388-1",
                "protein_name": "Mitochondrial import receptor subunit TOM20 homolog",
                "gene_name": "TOMM20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A6NCW0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3",
                "gene_name": "USP17L3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "A8MUK1-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 5",
                "gene_name": "USP17L5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9J2P7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 15",
                "gene_name": "USP17L15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JVI0-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 11",
                "gene_name": "USP17L11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R9N7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 18",
                "gene_name": "USP17L18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6RA61-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 22",
                "gene_name": "USP17L22",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0C7I0-1",
                "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 8",
                "gene_name": "USP17L8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "D6R901-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21",
                "gene_name": "USP17L21",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q0WX57-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24",
                "gene_name": "USP17L24; USP17L25; USP17L26; USP17L27; USP17L28; USP17L29; USP17L30",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60900-1",
                "protein_name": "Proteasome subunit alpha type-6",
                "gene_name": "PSMA6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13490-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 2",
                "gene_name": "BIRC2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62979-1",
                "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein",
                "gene_name": "RPS27A",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P60484-1",
                "protein_name": "Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN",
                "gene_name": "PTEN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P51784-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 11",
                "gene_name": "USP11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H7L9-1",
                "protein_name": "Sin3 histone deacetylase corepressor complex component SDS3",
                "gene_name": "SUDS3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P01106-2",
                "protein_name": "Myc proto-oncogene protein",
                "gene_name": "MYC",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P21796-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC1",
                "gene_name": "VDAC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4A5-1",
                "protein_name": "Transformation/transcription domain-associated protein",
                "gene_name": "TRRAP",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96FW1-1",
                "protein_name": "Ubiquitin thioesterase OTUB1",
                "gene_name": "OTUB1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P13569-1",
                "protein_name": "Cystic fibrosis transmembrane conductance regulator",
                "gene_name": "CFTR",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q13489-1",
                "protein_name": "Baculoviral IAP repeat-containing protein 3",
                "gene_name": "BIRC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5QNW6-1",
                "protein_name": "Histone H2B type 2-F",
                "gene_name": "H2BC18",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P33778-1",
                "protein_name": "Histone H2B type 1-B",
                "gene_name": "H2BC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P58876-1",
                "protein_name": "Histone H2B type 1-D",
                "gene_name": "H2BC5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96A08-1",
                "protein_name": "Histone H2B type 1-A",
                "gene_name": "H2BC1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P23527-1",
                "protein_name": "Histone H2B type 1-O",
                "gene_name": "H2BC17",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BYX4-1",
                "protein_name": "Interferon-induced helicase C domain-containing protein 1",
                "gene_name": "IFIH1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9UHP3-2",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25",
                "gene_name": "USP25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9H9J4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 42",
                "gene_name": "USP42",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P48556-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 8",
                "gene_name": "PSMD8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q15008-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 6",
                "gene_name": "PSMD6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28072-1",
                "protein_name": "Proteasome subunit beta type-6",
                "gene_name": "PSMB6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00232-1",
                "protein_name": "26S proteasome non-ATPase regulatory subunit 12",
                "gene_name": "PSMD12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P25787-1",
                "protein_name": "Proteasome subunit alpha type-2",
                "gene_name": "PSMA2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P28066-1",
                "protein_name": "Proteasome subunit alpha type-5",
                "gene_name": "PSMA5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q5XPI4-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF123",
                "gene_name": "RNF123",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93008-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 9X",
                "gene_name": "USP9X",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O60814-1",
                "protein_name": "Histone H2B type 1-K",
                "gene_name": "H2BC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93077-1",
                "protein_name": "Histone H2A type 1-C",
                "gene_name": "H2AC6",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q93079-1",
                "protein_name": "Histone H2B type 1-H",
                "gene_name": "H2BC9",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96KK5-1",
                "protein_name": "Histone H2A type 1-H",
                "gene_name": "H2AC12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q99879-1",
                "protein_name": "Histone H2B type 1-M",
                "gene_name": "H2BC14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y6I4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 3",
                "gene_name": "USP3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q96RU2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 28",
                "gene_name": "USP28",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q70CQ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 34",
                "gene_name": "USP34",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O94826-1",
                "protein_name": "Mitochondrial import receptor subunit TOM70",
                "gene_name": "TOMM70",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q86T82-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 37",
                "gene_name": "USP37",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9BXU7-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 26",
                "gene_name": "USP26",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6R6M4-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17",
                "gene_name": "USP17L2",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7RTZ2-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1",
                "gene_name": "USP17L1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HBM6-1",
                "protein_name": "Transcription initiation factor TFIID subunit 9B",
                "gene_name": "TAF9B",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y277-1",
                "protein_name": "Non-selective voltage-gated ion channel VDAC3",
                "gene_name": "VDAC3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75317-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 12",
                "gene_name": "USP12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "C9JPN9-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12",
                "gene_name": "USP17L12",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O75528-1",
                "protein_name": "Transcriptional adapter 3",
                "gene_name": "TADA3",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q12962-1",
                "protein_name": "Transcription initiation factor TFIID subunit 10",
                "gene_name": "TAF10",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y4E8-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 15",
                "gene_name": "USP15",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P0CG47-1",
                "protein_name": "Polyubiquitin-B",
                "gene_name": "UBB",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9HAW4-1",
                "protein_name": "Claspin",
                "gene_name": "CLSPN",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8TBZ3-1",
                "protein_name": "WD repeat-containing protein 20",
                "gene_name": "WDR20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P45974-1",
                "protein_name": "Ubiquitin carboxyl-terminal hydrolase 5",
                "gene_name": "USP5",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P62987-1",
                "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein",
                "gene_name": "UBA52",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O00487-1",
                "protein_name": "Ubiquitin C-terminal hydrolase PSMD14",
                "gene_name": "PSMD14",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9Y256-1",
                "protein_name": "CAAX prenyl protease 2",
                "gene_name": "RCE1",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q9NTX7-1",
                "protein_name": "E3 ubiquitin-protein ligase RNF146",
                "gene_name": "RNF146",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "O95760-1",
                "protein_name": "Interleukin-33",
                "gene_name": "IL33",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P04908-1",
                "protein_name": "Histone H2A type 1-B/E",
                "gene_name": "H2AC4; H2AC8",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P06899-1",
                "protein_name": "Histone H2B type 1-J",
                "gene_name": "H2BC11",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "P20671-1",
                "protein_name": "Histone H2A type 1-D",
                "gene_name": "H2AC7",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q16777-1",
                "protein_name": "Histone H2A type 2-C",
                "gene_name": "H2AC20",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q6FI13-1",
                "protein_name": "Histone H2A type 2-A",
                "gene_name": "H2AC18; H2AC19",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q7L7L0-1",
                "protein_name": "Histone H2A type 3",
                "gene_name": "H2AC25",
                "tax_name": "Human"
            },
            {
                "uniprot_canonical_ac": "Q8IUE6-1",
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    {
        "title": "The E3 ubiquitin-ligase HACE1 catalyzes the ubiquitylation of active Rac1.",
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