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Cell. Endocrinol.", "date": "2004", "authors": "Shimada Norihiro, Suzuki Takashi, Inoue Satoshi, Kato Katsuaki, Imatani Akira, Sekine Hitoshi, Ohara Syuichi, Shimosegawa Tooru, Sasano Hironobu", "reference": { "type": "PubMed", "id": "15130519", "url": "https://pubmed.ncbi.nlm.nih.gov/15130519" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14258", "url": "https://www.uniprot.org/uniprotkb/Q14258" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15130519", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], 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"2017", "authors": "Li Melody M H, Lau Zerlina, Cheung Pamela, Aguilar Eduardo G, Schneider William M, Bozzacco Leonia, Molina Henrik, Buehler Eugen, Takaoka Akinori, Rice Charles M, Felsenfeld Dan P, MacDonald Margaret R", "reference": { "type": "PubMed", "id": "28060952", "url": "https://pubmed.ncbi.nlm.nih.gov/28060952" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14258", "url": "https://www.uniprot.org/uniprotkb/Q14258" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.28060952", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { 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deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.", "journal": "PLoS pathogens", "date": "2018", "authors": "Gupta S, Yla-Anttila P, Callegari S, Tsai MH, Delecluse HJ, Masucci MG", "reference": { "type": "PubMed", "id": "29357390", "url": "https://pubmed.ncbi.nlm.nih.gov/29357390" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63104-1", "protein_name": "14-3-3 protein zeta/delta", "gene_name": "YWHAZ", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q14258", "url": "https://www.uniprot.org/uniprotkb/Q14258" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.29357390", "abstract": "", 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function and oxidative stress.", "journal": "Free radical biology & medicine", "date": "2022-08-01", "authors": "Zhu Jing, Ma Xirui, Jing Yu, Zhang Guangya, Zhang Dandan, Mao Ziming, Ma Xiaowen, Liu Huifang, Chen Fengling", "reference": { "type": "PubMed", "id": "35753586", "url": "https://pubmed.ncbi.nlm.nih.gov/35753586" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q96HY6-1", "protein_name": "DDRGK domain-containing protein 1", "gene_name": "DDRGK1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94874-1", "protein_name": "E3 UFM1-protein ligase 1", "gene_name": "UFL1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q96HY6", "url": "https://www.uniprot.org/uniprotkb/Q96HY6" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.35753586", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase.", "journal": "Br. J. Cancer", "date": "2003", "authors": "Subramaniam V, Li H, Wong M, Kitching R, Attisano L, Wrana J, Zubovits J, Burger AM, Seth A", "reference": { "type": "PubMed", "id": "14562029", "url": "https://pubmed.ncbi.nlm.nih.gov/14562029" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HAU4-1", "protein_name": "E3 ubiquitin-protein ligase SMURF2", "gene_name": "SMURF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3C5-1", "protein_name": "RING finger protein 11", "gene_name": "RNF11", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P51668", "url": "https://www.uniprot.org/uniprotkb/P51668" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 102, "end_pos": 102, "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on STAMBP- and SMURF2-binding; when associated with S-99. No effect on ubiquitination by ITCH; when associated with S-102. No effect on STAMBP-binding; when associated with A-40 and S-99.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y3C5", "url": "https://www.uniprot.org/uniprotkb/Q9Y3C5" }, { "database": "PubMed", "id": "14562029", "url": "https://pubmed.ncbi.nlm.nih.gov/14562029" }, { "database": "PubMed", "id": "14755250", "url": "https://pubmed.ncbi.nlm.nih.gov/14755250" }, { "database": "PubMed", "id": "20676133", "url": "https://pubmed.ncbi.nlm.nih.gov/20676133" } ], "uniprot_canonical_ac": "Q9Y3C5-1" }, { "start_pos": 40, "end_pos": 40, "sequence_org": "Y", "sequence_mut": "A", "comment": "Loss of ITCH-, SMURF2- and WWP1-binding. Partial loss of ubiquitination by ITCH. No effect on STAMBP-binding; when associated with S-99 and S-102. Persistent TNF-mediated NFKBIA phosphorylation. Loss of stimulus-dependent complex formation with TAX1BP1, TNFAIP3 and RIPK1.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y3C5", "url": "https://www.uniprot.org/uniprotkb/Q9Y3C5" }, { "database": "PubMed", "id": "14562029", "url": "https://pubmed.ncbi.nlm.nih.gov/14562029" }, { "database": "PubMed", "id": "19131965", "url": "https://pubmed.ncbi.nlm.nih.gov/19131965" }, { "database": "PubMed", "id": "14755250", "url": "https://pubmed.ncbi.nlm.nih.gov/14755250" }, { "database": "PubMed", "id": "18724389", "url": "https://pubmed.ncbi.nlm.nih.gov/18724389" }, { "database": "PubMed", "id": "14559117", "url": "https://pubmed.ncbi.nlm.nih.gov/14559117" } ], "uniprot_canonical_ac": "Q9Y3C5-1" }, { "start_pos": 99, "end_pos": 99, "sequence_org": "C", "sequence_mut": "S", "comment": "No effect on STAMBP- and SMURF2-binding; when associated with S-102. Persistent TNF-mediated NFKBIA phosphorylation. No effect on STAMBP-binding; when associated with A-40 and S-102. No effect on ubiquitination by ITCH; when associated with S-102. Loss of stimulus-dependent complex formation with TAX1BP1, TNFAIP3 and RIPK1.", "evidence": [ { "database": "UniProtKB", "id": "Q9Y3C5", "url": "https://www.uniprot.org/uniprotkb/Q9Y3C5" }, { "database": "PubMed", "id": "14562029", "url": "https://pubmed.ncbi.nlm.nih.gov/14562029" }, { "database": "PubMed", "id": "19131965", "url": "https://pubmed.ncbi.nlm.nih.gov/19131965" }, { "database": "PubMed", "id": "14755250", "url": "https://pubmed.ncbi.nlm.nih.gov/14755250" }, { "database": "PubMed", "id": "20676133", "url": "https://pubmed.ncbi.nlm.nih.gov/20676133" } ], "uniprot_canonical_ac": "Q9Y3C5-1" } ], "record_id": "pubmed.14562029", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", 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"Heat shock protein HSP 90-beta", "gene_name": "HSP90AB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62837-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D2", "gene_name": "UBE2D2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UNE7-1", "protein_name": "E3 ubiquitin-protein ligase CHIP", "gene_name": "STUB1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P51668", "url": "https://www.uniprot.org/uniprotkb/P51668" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18042044", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", 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}, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": 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Cell Res.", "date": "2008", "authors": "Espinosa Alexander, Oke Vilija, Elfving Ase, Nyberg Filippa, Covacu Ruxandra, Wahren-Herlenius Marie", "reference": { "type": "PubMed", "id": "18845142", "url": "https://pubmed.ncbi.nlm.nih.gov/18845142" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51965-1", "protein_name": "Ubiquitin-conjugating enzyme E2 E1", "gene_name": "UBE2E1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19474-1", "protein_name": "E3 ubiquitin-protein ligase TRIM21", "gene_name": "TRIM21", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P51668", "url": "https://www.uniprot.org/uniprotkb/P51668" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": 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Cell Biol.", "date": "1997", "authors": "Gutierrez J A, Yu J, Rivera S, Wessling-Resnick M", "reference": { "type": "PubMed", "id": "9362508", "url": "https://pubmed.ncbi.nlm.nih.gov/9362508" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P51668-1", "protein_name": "Ubiquitin-conjugating enzyme E2 D1", "gene_name": "UBE2D1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P51668", "url": "https://www.uniprot.org/uniprotkb/P51668" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.9362508", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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Chem.", "date": "1990", "authors": "Zapf J, Kiefer M, Merryweather J, Musiarz F, Bauer D, Born W, Fischer J A, Froesch E R", "reference": { "type": "PubMed", "id": "1697583", "url": "https://pubmed.ncbi.nlm.nih.gov/1697583" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P17936-1", "protein_name": "Insulin-like growth factor-binding protein 3", "gene_name": "IGFBP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18065-1", "protein_name": "Insulin-like growth factor-binding protein 2", "gene_name": "IGFBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P24592-1", "protein_name": "Insulin-like growth factor-binding protein 6", "gene_name": "IGFBP6", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P17936", "url": "https://www.uniprot.org/uniprotkb/P17936" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": 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Isolation of IGFBP-2, an altered form of IGFBP-3 and a new IGFBP species.", "journal": "Growth Regul.", "date": "1991", "authors": "Roghani M, Segovia B, Whitechurch O, Binoux M", "reference": { "type": "PubMed", "id": "1726837", "url": "https://pubmed.ncbi.nlm.nih.gov/1726837" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P17936-1", "protein_name": "Insulin-like growth factor-binding protein 3", "gene_name": "IGFBP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18065-1", "protein_name": "Insulin-like growth factor-binding protein 2", "gene_name": "IGFBP2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P17936", "url": "https://www.uniprot.org/uniprotkb/P17936" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.1726837", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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"count": 0 } ], "sort_fields": [] } ] }, { "title": "C-Src confers resistance to mitotic stress through inhibition DMAP1/Bub3 complex formation in pancreatic cancer.", "journal": "Molecular cancer", "date": "2018", "authors": "Li J, Hu B, Wang T, Huang W, Ma C, Zhao Q, Zhuo L, Zhang T, Jiang Y", "reference": { "type": "PubMed", "id": "30553276", "url": "https://pubmed.ncbi.nlm.nih.gov/30553276" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9NPF5-1", "protein_name": "DNA methyltransferase 1-associated protein 1", "gene_name": "DMAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O43684-1", "protein_name": "Mitotic checkpoint protein BUB3", "gene_name": "BUB3", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9NPF5", "url": "https://www.uniprot.org/uniprotkb/Q9NPF5" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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