[ { "title": "Unique binding interactions among Ubc9, SUMO and RanBP2 reveal a mechanism for SUMO paralog selection.", "journal": "Nature structural & molecular biology", "date": "2005", "authors": "Tatham MH, Kim S, Jaffray E, Song J, Chen Y, Hay RT", "reference": { "type": "PubMed", "id": "15608651", "url": "https://pubmed.ncbi.nlm.nih.gov/15608651" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase 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"uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27695-1", "protein_name": "DNA repair nuclease/redox regulator APEX1", "gene_name": "APEX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95243-1", "protein_name": "Methyl-CpG-binding domain protein 4", "gene_name": "MBD4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53HV7-1", "protein_name": "Single-strand selective monofunctional uracil DNA glycosylase", "gene_name": "SMUG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29372-1", "protein_name": "DNA-3-methyladenine glycosylase", "gene_name": "MPG", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15823533", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 78 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Intra-nuclear trafficking of the BLM helicase to DNA damage-induced foci is regulated by SUMO modification.", "journal": "Human molecular genetics", "date": "2005", "authors": "Eladad S, Ye TZ, Hu P, Leversha M, Beresten S, Matunis MJ, Ellis NA", "reference": { "type": "PubMed", "id": "15829507", "url": "https://pubmed.ncbi.nlm.nih.gov/15829507" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO-dependent compartmentalization in promyelocytic leukemia protein nuclear bodies prevents the access of LRH-1 to chromatin.", "journal": "Molecular and cellular biology", "date": "2005", "authors": "Chalkiadaki A, Talianidis I", "reference": { "type": "PubMed", "id": "15923626", "url": "https://pubmed.ncbi.nlm.nih.gov/15923626" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10276-1", "protein_name": "Retinoic acid receptor alpha", "gene_name": "RARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06401-1", "protein_name": "Progesterone receptor", "gene_name": "PGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15923626", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO-modified PCNA recruits Srs2 to prevent recombination during S phase.", "journal": "Nature", "date": "2005", "authors": "Pfander B, Moldovan GL, Sacher M, Hoege C, Jentsch S", "reference": { "type": "PubMed", "id": "15931174", "url": "https://pubmed.ncbi.nlm.nih.gov/15931174" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14965-1", "protein_name": "Aurora kinase A", "gene_name": "AURKA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11388-1", "protein_name": "DNA topoisomerase 2-alpha", "gene_name": "TOP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15392-1", "protein_name": "Baculoviral IAP repeat-containing protein 5", "gene_name": "BIRC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQS7-1", "protein_name": "Inner centromere protein", "gene_name": "INCENP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11387-1", "protein_name": "DNA topoisomerase 1", "gene_name": "TOP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GD4-1", "protein_name": "Aurora kinase B", "gene_name": "AURKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12004-1", "protein_name": "DNA sliding clamp PCNA", "gene_name": "PCNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53HL2-1", "protein_name": "Borealin", "gene_name": "CDCA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { 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"Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15931174", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 43 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Stabilization of PML nuclear localization by conjugation and oligomerization of SUMO-3.", "journal": "Oncogene", "date": "2005", "authors": "Fu C, Ahmed K, Ding H, Ding X, Lan J, Yang Z, Miao Y, Zhu Y, Shi Y, Zhu J, Huang H, Yao X", "reference": { "type": "PubMed", "id": "15940266", "url": "https://pubmed.ncbi.nlm.nih.gov/15940266" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex 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"protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": 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7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 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"protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15940266", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Regulation of homeodomain-interacting protein kinase 2 (HIPK2) effector function through dynamic small ubiquitin-related modifier-1 (SUMO-1) modification.", "journal": "The Journal of biological chemistry", "date": "2005", "authors": "Hofmann TG, Jaffray E, Stollberg N, Hay RT, Will H", "reference": { "type": 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}, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sumoylation of the estrogen receptor alpha hinge region regulates its transcriptional activity.", "journal": "Molecular endocrinology (Baltimore, Md.)", "date": "2005", "authors": "Sentis S, Le Romancer M, Bianchin C, Rostan MC, Corbo L", "reference": { "type": "PubMed", "id": "15961505", "url": "https://pubmed.ncbi.nlm.nih.gov/15961505" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10276-1", "protein_name": "Retinoic acid receptor alpha", "gene_name": "RARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06401-1", "protein_name": "Progesterone receptor", "gene_name": "PGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15961505", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Proper SUMO-1 conjugation is essential to DJ-1 to exert its full activities.", "journal": "Cell death and differentiation", "date": "2006", "authors": "Shinbo Y, Niki T, Taira T, Ooe H, Takahashi-Niki K, Maita C, Seino C, Iguchi-Ariga SM, Ariga H", "reference": { "type": "PubMed", "id": "15976810", "url": "https://pubmed.ncbi.nlm.nih.gov/15976810" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9VA37-1", "protein_name": "Protein dj-1beta", "gene_name": "dj-1beta", "tax_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8UW59-1", "protein_name": "Protein/nucleic acid deglycase DJ-1", "gene_name": "PARK7", "tax_name": "Chicken" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75928-1", "protein_name": "E3 SUMO-protein ligase PIAS2", "gene_name": "PIAS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15976810", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 45 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p.", "journal": "Molecular cell", "date": "2005", "authors": "Papouli E, Chen S, Davies AA, Huttner D, Krejci L, Sung P, Ulrich HD", "reference": { "type": "PubMed", "id": "15989970", "url": "https://pubmed.ncbi.nlm.nih.gov/15989970" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14965-1", "protein_name": "Aurora kinase A", "gene_name": "AURKA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11388-1", "protein_name": "DNA topoisomerase 2-alpha", "gene_name": "TOP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15392-1", "protein_name": "Baculoviral IAP repeat-containing protein 5", "gene_name": "BIRC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQS7-1", "protein_name": "Inner centromere protein", "gene_name": "INCENP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11387-1", "protein_name": "DNA topoisomerase 1", "gene_name": "TOP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GD4-1", "protein_name": "Aurora kinase B", "gene_name": "AURKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12004-1", "protein_name": "DNA sliding clamp PCNA", "gene_name": "PCNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53HL2-1", "protein_name": "Borealin", "gene_name": "CDCA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46060-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02880-1", "protein_name": "DNA topoisomerase 2-beta", "gene_name": "TOP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.15989970", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 43 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "DNA repair factor XPC is modified by SUMO-1 and ubiquitin following UV irradiation.", "journal": "Nucleic acids research", "date": "2005", "authors": "Wang QE, Zhu Q, Wani G, El-Mahdy MA, Li J, Wani AA", "reference": { "type": "PubMed", "id": "16030353", "url": "https://pubmed.ncbi.nlm.nih.gov/16030353" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54727-1", "protein_name": "Lysine-specific demethylase RAD23B", "gene_name": "RAD23B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13888-1", "protein_name": "General transcription factor IIH subunit 2", "gene_name": "GTF2H2C_2; GTF2H2C; GTF2H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92759-1", "protein_name": "General transcription factor IIH subunit 4", "gene_name": "GTF2H4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19447-1", "protein_name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "gene_name": "ERCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28715-1", "protein_name": "DNA excision repair protein ERCC-5", "gene_name": "ERCC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UGN5-1", "protein_name": "Poly [ADP-ribose] polymerase 2", "gene_name": "PARP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZYL4-1", "protein_name": "General transcription factor IIH subunit 5", "gene_name": "GTF2H5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07992-1", "protein_name": "DNA excision repair protein ERCC-1", "gene_name": "ERCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16531-1", "protein_name": "DNA damage-binding protein 1", "gene_name": "DDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WJ1-1", "protein_name": "ATP-dependent chromatin remodeler CHD1L", "gene_name": "CHD1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32780-1", "protein_name": "General transcription factor IIH subunit 1", "gene_name": "GTF2H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13889-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "GTF2H3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92466-1", "protein_name": "DNA damage-binding protein 2", "gene_name": "DDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62877-1", "protein_name": "E3 ubiquitin-protein ligase RBX1", "gene_name": "RBX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18074-1", "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "ERCC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51948-1", "protein_name": "CDK-activating kinase assembly factor MAT1", "gene_name": "MNAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51946-1", "protein_name": "Cyclin-H", "gene_name": "CCNH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54725-1", "protein_name": "Lysine-specific demethylase RAD23A", "gene_name": "RAD23A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZNA4-1", "protein_name": "E3 ubiquitin-protein ligase Arkadia", "gene_name": "RNF111", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13619-1", "protein_name": "Cullin-4A", "gene_name": "CUL4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13620-2", "protein_name": "Cullin-4B", "gene_name": "CUL4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q70EL2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 45", "gene_name": "USP45", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50613-1", "protein_name": "Cyclin-dependent kinase 7", "gene_name": "CDK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92889-1", "protein_name": "DNA repair endonuclease XPF", "gene_name": "ERCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23025-1", "protein_name": "DNA repair protein complementing XP-A cells", "gene_name": "XPA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16030353", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 106 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Transcriptional activity of megakaryoblastic leukemia 1 (MKL1) is repressed by SUMO modification.", "journal": "Genes to cells : devoted to molecular & cellular mechanisms", "date": "2005", "authors": "Nakagawa K, Kuzumaki N", "reference": { "type": "PubMed", "id": "16098147", "url": "https://pubmed.ncbi.nlm.nih.gov/16098147" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16098147", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Desumoylation of homeodomain-interacting protein kinase 2 (HIPK2) through the cytoplasmic-nuclear shuttling of the SUMO-specific protease SENP1.", "journal": "FEBS letters", "date": "2005", "authors": "Kim YH, Sung KS, Lee SJ, Kim YO, Choi CY, Kim Y", "reference": { "type": "PubMed", "id": "16253240", "url": "https://pubmed.ncbi.nlm.nih.gov/16253240" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC62-1", "protein_name": "Sentrin-specific protease 2", "gene_name": "SENP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P0U3-1", "protein_name": "Sentrin-specific protease 1", "gene_name": "SENP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HI0-1", "protein_name": "Sentrin-specific protease 5", "gene_name": "SENP5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16253240", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO modification of human XRCC4 regulates its localization and function in DNA double-strand break repair.", "journal": "Molecular and cellular biology", "date": "2006", "authors": "Yurchenko V, Xue Z, Sadofsky MJ", "reference": { "type": "PubMed", "id": "16478998", "url": "https://pubmed.ncbi.nlm.nih.gov/16478998" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": 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"uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", 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"gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": 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}, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": 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Does not affect nuclear localization of XRCC4 and LIG4.", "evidence": [ { "database": "UniProtKB", "id": "Q13426", "url": "https://www.uniprot.org/uniprotkb/Q13426" }, { "database": "PubMed", "id": "16478998", "url": "https://pubmed.ncbi.nlm.nih.gov/16478998" }, { "database": "PubMed", "id": "25934149", "url": "https://pubmed.ncbi.nlm.nih.gov/25934149" } ], "uniprot_canonical_ac": "Q13426-1" } ], "record_id": "pubmed.16478998", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q92466-1", "protein_name": "DNA damage-binding protein 2", "gene_name": "DDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62877-1", "protein_name": "E3 ubiquitin-protein ligase RBX1", "gene_name": "RBX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18074-1", "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "ERCC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51948-1", "protein_name": "CDK-activating kinase assembly factor MAT1", "gene_name": "MNAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51946-1", "protein_name": "Cyclin-H", "gene_name": "CCNH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54725-1", "protein_name": "Lysine-specific demethylase RAD23A", "gene_name": "RAD23A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZNA4-1", "protein_name": "E3 ubiquitin-protein ligase Arkadia", "gene_name": "RNF111", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13619-1", "protein_name": "Cullin-4A", "gene_name": "CUL4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13620-2", "protein_name": "Cullin-4B", "gene_name": "CUL4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q70EL2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 45", "gene_name": "USP45", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50613-1", "protein_name": "Cyclin-dependent kinase 7", "gene_name": "CDK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92889-1", "protein_name": "DNA repair endonuclease XPF", "gene_name": "ERCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23025-1", "protein_name": "DNA repair protein complementing XP-A cells", "gene_name": "XPA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16491090", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 43 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The structure of SENP1-SUMO-2 complex suggests a structural basis for discrimination between SUMO paralogues during processing.", "journal": "Biochem. J.", "date": "2006", "authors": "Shen LN, Dong C, Liu H, Naismith JH, Hay RT", "reference": { "type": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P0U3-1", "protein_name": "Sentrin-specific protease 1", "gene_name": "SENP1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 441, "end_pos": 441, "sequence_org": "D", "sequence_mut": "A", "comment": "No effect on SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 465, "end_pos": 465, "sequence_org": "W", "sequence_mut": "A", "comment": "Impairs SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 468, "end_pos": 468, "sequence_org": "D", "sequence_mut": "A", "comment": "Slightly impairs SUMO2 processing activity. No effect on SUMO2 deconjugating activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 496, "end_pos": 496, "sequence_org": "F", "sequence_mut": "A", "comment": "Impairs SUMO2 processing activity. No effect on SUMO2 deconjugating activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 511, "end_pos": 511, "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs SUMO2 processing activity. No effect on SUMO2 deconjugating activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 512, "end_pos": 512, "sequence_org": "W", "sequence_mut": "A", "comment": "Impairs SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 529, "end_pos": 529, "sequence_org": "H", "sequence_mut": "A", "comment": "Impairs SUMO2 processing activity. No effect on SUMO2 deconjugating activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 532, "end_pos": 532, "sequence_org": "V", "sequence_mut": "A", "comment": "No effect on SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 533, "end_pos": 533, "sequence_org": "H", "sequence_mut": "A", "comment": "Abolishes SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 534, "end_pos": 534, "sequence_org": "W", "sequence_mut": "A", "comment": "Abolishes SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 550, "end_pos": 550, "sequence_org": "D", "sequence_mut": "A", "comment": "Abolishes SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 597, "end_pos": 597, "sequence_org": "Q", "sequence_mut": "A", "comment": "Abolishes SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 603, "end_pos": 603, "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" }, { "database": "PubMed", "id": "16712526", "url": "https://pubmed.ncbi.nlm.nih.gov/16712526" }, { "database": "PubMed", "id": "14563852", "url": "https://pubmed.ncbi.nlm.nih.gov/14563852" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 603, "end_pos": 603, "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes SUMO2 processing and SUMO2 deconjugating activities.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" }, { "database": "PubMed", "id": "16712526", "url": "https://pubmed.ncbi.nlm.nih.gov/16712526" }, { "database": "PubMed", "id": "14563852", "url": "https://pubmed.ncbi.nlm.nih.gov/14563852" } ], "uniprot_canonical_ac": "Q9P0U3-1" }, { "start_pos": 603, "end_pos": 603, "sequence_org": "C", "sequence_mut": "S", "comment": "Exclusively nuclear. Loss of CCAR2 desumoylation.", "evidence": [ { "database": "UniProtKB", "id": "Q9P0U3", "url": "https://www.uniprot.org/uniprotkb/Q9P0U3" }, { "database": "PubMed", "id": "25406032", "url": "https://pubmed.ncbi.nlm.nih.gov/25406032" }, { "database": "PubMed", "id": "16553580", "url": "https://pubmed.ncbi.nlm.nih.gov/16553580" }, { "database": "PubMed", "id": "16712526", "url": "https://pubmed.ncbi.nlm.nih.gov/16712526" }, { "database": "PubMed", "id": "14563852", "url": "https://pubmed.ncbi.nlm.nih.gov/14563852" } ], "uniprot_canonical_ac": "Q9P0U3-1" } ], "record_id": "pubmed.16553580", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Characterization of a family of nucleolar SUMO-specific proteases with preference for SUMO-2 or SUMO-3.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Gong L, Yeh ET", "reference": { "type": "PubMed", "id": "16608850", "url": "https://pubmed.ncbi.nlm.nih.gov/16608850" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC62-1", "protein_name": "Sentrin-specific protease 2", "gene_name": "SENP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4L4-1", "protein_name": "Sentrin-specific protease 3", "gene_name": "SENP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P0U3-1", "protein_name": 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"protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HI0-1", "protein_name": "Sentrin-specific protease 5", "gene_name": "SENP5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 713, "end_pos": 713, "sequence_org": "C", "sequence_mut": "A", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q96HI0", "url": "https://www.uniprot.org/uniprotkb/Q96HI0" }, { "database": "PubMed", "id": "16608850", "url": "https://pubmed.ncbi.nlm.nih.gov/16608850" }, { "database": "PubMed", "id": "16738315", "url": "https://pubmed.ncbi.nlm.nih.gov/16738315" } ], "uniprot_canonical_ac": "Q96HI0-1" } ], "record_id": "pubmed.16608850", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 76 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Crystal structure of SUMO-3-modified thymine-DNA glycosylase.", "journal": "Journal of molecular biology", "date": "2006", "authors": "Baba D, Maita N, Jee JG, Uchimura Y, Saitoh H, Sugasawa K, Hanaoka F, Tochio H, Hiroaki H, Shirakawa M", "reference": { "type": "PubMed", "id": "16626738", "url": "https://pubmed.ncbi.nlm.nih.gov/16626738" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": 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"protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 310, "end_pos": 310, "sequence_org": "E", "sequence_mut": "Q", "comment": "Restores the DNA-binding ability of the sumoylated form.", "evidence": [ { "database": "UniProtKB", "id": "Q13569", "url": "https://www.uniprot.org/uniprotkb/Q13569" }, { "database": "PubMed", "id": "16626738", "url": "https://pubmed.ncbi.nlm.nih.gov/16626738" }, { "database": "PubMed", "id": "15959518", "url": "https://pubmed.ncbi.nlm.nih.gov/15959518" } ], "uniprot_canonical_ac": "Q13569-1" } ], "record_id": "pubmed.16626738", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": 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"P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein 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"uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 551, "end_pos": 551, "sequence_org": "K", "sequence_mut": "Q", "comment": "A decreased interaction with HDAC1 and deacetylation of SP3. Increase of about 4.5% of activity of the TERT promoter. Decreased recruitment of HDAC1 and increased binding of RNA polymerase II with promoter DNA.", "evidence": [ { "database": "UniProtKB", "id": "Q02447", "url": "https://www.uniprot.org/uniprotkb/Q02447" }, { "database": "PubMed", "id": "16781829", "url": "https://pubmed.ncbi.nlm.nih.gov/16781829" }, { "database": "PubMed", "id": "17548428", "url": "https://pubmed.ncbi.nlm.nih.gov/17548428" }, { "database": "PubMed", "id": "12419227", "url": "https://pubmed.ncbi.nlm.nih.gov/12419227" } ], "uniprot_canonical_ac": "Q02447-1" }, { "start_pos": 551, "end_pos": 551, "sequence_org": "K", "sequence_mut": "R", "comment": "Great loss of sumoylation, 20-fold increase in transcriptional activity and diffuse nuclear localization. Further small increase in transcriptional activity; when associated with R-120. Increased interaction with HDAC1 and deacetylation of SP3. About 50% decrease in activity of the TERT promoter. Enhances recruitment of HDAC1 and inhibits binding of RNA polymerase II with promoter DNA.", "evidence": [ { "database": "UniProtKB", "id": "Q02447", "url": "https://www.uniprot.org/uniprotkb/Q02447" }, { "database": "PubMed", "id": "12419227", "url": "https://pubmed.ncbi.nlm.nih.gov/12419227" }, { "database": "PubMed", "id": "16781829", "url": "https://pubmed.ncbi.nlm.nih.gov/16781829" }, { "database": "PubMed", "id": "17548428", "url": "https://pubmed.ncbi.nlm.nih.gov/17548428" } ], "uniprot_canonical_ac": "Q02447-1" } ], "record_id": "pubmed.16781829", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 18 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", 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"gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": 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"protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PIASy mediates NEMO sumoylation and NF-kappaB activation in response to genotoxic stress.", "journal": "Nature cell biology", "date": "2006", "authors": "Mabb AM, Wuerzberger-Davis SM, Miyamoto S", "reference": { "type": "PubMed", "id": "16906147", "url": "https://pubmed.ncbi.nlm.nih.gov/16906147" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related 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"TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.16906147", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Negative modulation of RXRalpha transcriptional activity by small ubiquitin-related modifier (SUMO) modification and its reversal by SUMO-specific protease SUSP1.", "journal": "The Journal of biological chemistry", "date": "2006", "authors": "Choi SJ, Chung SS, Rho EJ, Lee HW, Lee MH, Choi HS, Seol JH, Baek SH, Bang OS, Chung CH", "reference": { "type": 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"protein_name": "Sentrin-specific protease 6", "gene_name": "SENP6", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06401-1", "protein_name": "Progesterone receptor", "gene_name": "PGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 1030, "end_pos": 1030, "sequence_org": "C", "sequence_mut": "S", "comment": "Abolishes enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9GZR1", "url": "https://www.uniprot.org/uniprotkb/Q9GZR1" }, { "database": "PubMed", "id": "16912044", "url": "https://pubmed.ncbi.nlm.nih.gov/16912044" } ], "uniprot_canonical_ac": "Q9GZR1-1" } ], "record_id": "pubmed.16912044", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 25 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { 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"glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation-dependent control of Pc2 SUMO E3 ligase activity by its substrate protein HIPK2.", "journal": "Molecular cell", "date": "2006", "authors": "Roscic A, Moller A, Calzado MA, Renner F, Wimmer VC, Gresko E, Ludi KS, Schmitz ML", "reference": { "type": "PubMed", "id": "17018294", "url": "https://pubmed.ncbi.nlm.nih.gov/17018294" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969R5-1", "protein_name": "Lethal(3)malignant brain tumor-like protein 2", "gene_name": "L3MBTL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13547-1", "protein_name": "Histone deacetylase 1", "gene_name": "HDAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": 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"uniprot_canonical_ac": "Q01826-1", "protein_name": "DNA-binding protein SATB1", "gene_name": "SATB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96006-1", "protein_name": "E3 SUMO-protein ligase ZBED1", "gene_name": "ZBED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P45973-1", "protein_name": "Chromobox protein homolog 5", "gene_name": "CBX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12873-1", "protein_name": "ATP-dependent chromatin remodeler CHD3", "gene_name": "CHD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92769-1", "protein_name": "Histone deacetylase 2", "gene_name": "HDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPW6-1", "protein_name": "DNA-binding protein SATB2", "gene_name": "SATB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 497, "end_pos": 497, "kinase_uniprot_canonical_ac": "Q9H2X6-1", "kinase_gene_name": "HIPK2", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "O00257", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00257" }, { "database": "PubMed", "id": "17018294", "url": "https://pubmed.ncbi.nlm.nih.gov/17018294" } ], "site_lbl": "Thr497", "uniprot_canonical_ac": "O00257-1" }, { "start_pos": 497, "end_pos": 497, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "Phosphothreonine; by HIPK2", "evidence": [ { "database": "UniProtKB", "id": "O00257", "url": "https://www.uniprot.org/uniprotkb/O00257" }, { "database": "iPTMnet", "id": "O00257", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/O00257" }, { "database": "PubMed", "id": "17018294", "url": "https://pubmed.ncbi.nlm.nih.gov/17018294" } ], "site_lbl": "Thr497", "uniprot_canonical_ac": "O00257-1" } ], "record_id": "pubmed.17018294", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 54 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PIAS3 induction of PRB sumoylation represses PRB transactivation by destabilizing its retention in the nucleus.", "journal": "Nucleic acids research", "date": "2006", "authors": "Man JH, Li HY, Zhang PJ, Zhou T, He K, Pan X, Liang B, Li AL, Zhao J, Gong WL, Jin BF, Xia Q, Yu M, Shen BF, Zhang XM", "reference": { "type": "PubMed", "id": "17020914", "url": "https://pubmed.ncbi.nlm.nih.gov/17020914" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10276-1", "protein_name": "Retinoic acid receptor alpha", "gene_name": "RARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06401-1", "protein_name": "Progesterone receptor", "gene_name": "PGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 388, "end_pos": 388, "sequence_org": "K", "sequence_mut": "R", "comment": "Great loss of sumoylation; when associated with R-7. Completely abolishes sumoylation; when associated with R-7 and R-531. Loss of CUEDC2-mediated protein degradation. Increased ligand-dependent transcriptional activity.", "evidence": [ { "database": "UniProtKB", "id": "P06401", "url": "https://www.uniprot.org/uniprotkb/P06401" }, { "database": "PubMed", "id": "17020914", "url": "https://pubmed.ncbi.nlm.nih.gov/17020914" }, { "database": "PubMed", "id": "17717077", "url": "https://pubmed.ncbi.nlm.nih.gov/17717077" }, { "database": "PubMed", "id": "17347654", "url": "https://pubmed.ncbi.nlm.nih.gov/17347654" } ], "uniprot_canonical_ac": "P06401-1" }, { "start_pos": 531, "end_pos": 531, "sequence_org": "K", "sequence_mut": "R", "comment": "Some loss of sumoylation; when associated with R-7. Completely abolishes sumoylation; when associated with R-7 and R-388.", "evidence": [ { "database": "UniProtKB", "id": "P06401", "url": "https://www.uniprot.org/uniprotkb/P06401" }, { "database": "PubMed", "id": "17020914", "url": "https://pubmed.ncbi.nlm.nih.gov/17020914" } ], "uniprot_canonical_ac": "P06401-1" }, { "start_pos": 7, "end_pos": 7, "sequence_org": "K", "sequence_mut": "R", "comment": "Some loss of sumoylation; when associated with R-531. Complete loss of sumoylation; when associated with R-388 and R-531.", "evidence": [ { "database": "UniProtKB", "id": "P06401", "url": "https://www.uniprot.org/uniprotkb/P06401" }, { "database": "PubMed", "id": "17020914", "url": "https://pubmed.ncbi.nlm.nih.gov/17020914" } ], "uniprot_canonical_ac": "P06401-1" } ], "record_id": "pubmed.17020914", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Doxorubicin down-regulates Kruppel-associated box domain-associated protein 1 sumoylation that relieves its transcription repression on p21WAF1/CIP1 in breast cancer MCF-7 cells.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Lee YK, Thomas SN, Yang AJ, Ann DK", "reference": { "type": "PubMed", "id": "17079232", "url": "https://pubmed.ncbi.nlm.nih.gov/17079232" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { 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Impairs interaction with RBBP4 and MTA1 and no effect on interaction with CTBP2. 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Decreases interaction with MTA1.", "evidence": [ { "database": "UniProtKB", "id": "Q14526", "url": "https://www.uniprot.org/uniprotkb/Q14526" }, { "database": "PubMed", "id": "20547755", "url": "https://pubmed.ncbi.nlm.nih.gov/20547755" }, { "database": "PubMed", "id": "17283066", "url": "https://pubmed.ncbi.nlm.nih.gov/17283066" } ], "uniprot_canonical_ac": "Q14526-1" }, { "start_pos": 336, "end_pos": 336, "sequence_org": "P", "sequence_mut": "A", "comment": "Impairs K-333 acetylation; no effect on sumoylation. Decreases interaction with MTA1.", "evidence": [ { "database": "UniProtKB", "id": "Q14526", "url": "https://www.uniprot.org/uniprotkb/Q14526" }, { "database": "PubMed", "id": "20547755", "url": "https://pubmed.ncbi.nlm.nih.gov/20547755" }, { "database": "PubMed", "id": "17283066", "url": "https://pubmed.ncbi.nlm.nih.gov/17283066" } ], "uniprot_canonical_ac": "Q14526-1" } ], "record_id": "pubmed.17283066", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 19 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sumoylation of the transcriptional intermediary factor 1beta (TIF1beta), the Co-repressor of the KRAB Multifinger proteins, is required for its transcriptional activity and is modulated by the KRAB domain.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Mascle XH, Germain-Desprez D, Huynh P, Estephan P, Aubry M", "reference": { "type": "PubMed", "id": "17298944", "url": "https://pubmed.ncbi.nlm.nih.gov/17298944" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 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"uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sumoylation and proteasomal activity determine the transactivation properties of the mineralocorticoid receptor.", "journal": "Molecular and cellular endocrinology", "date": "2007", "authors": "Tirard M, Almeida OF, Hutzler P, Melchior F, Michaelidis TM", "reference": { "type": "PubMed", "id": "17314004", "url": "https://pubmed.ncbi.nlm.nih.gov/17314004" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", 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"gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06401-1", "protein_name": "Progesterone receptor", "gene_name": "PGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", 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"Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17314004", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO modification of the DEAD box protein p68 modulates its transcriptional activity and promotes its interaction with HDAC1.", "journal": "Oncogene", "date": "2007", "authors": "Jacobs AM, Nicol SM, Hislop RG, Jaffray EG, Hay RT, Fuller-Pace FV", "reference": { "type": "PubMed", "id": "17369852", "url": "https://pubmed.ncbi.nlm.nih.gov/17369852" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, 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ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17535915", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Small ubiquitin-related modifier (SUMO)-specific proteases: profiling the specificities and activities of human SENPs.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Mikolajczyk J, Drag M, Bekes M, Cao JT, Ronai Z, Salvesen GS", "reference": { "type": "PubMed", "id": "17591783", "url": "https://pubmed.ncbi.nlm.nih.gov/17591783" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC62-1", "protein_name": "Sentrin-specific protease 2", "gene_name": "SENP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9P0U3-1", "protein_name": "Sentrin-specific protease 1", "gene_name": "SENP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HI0-1", "protein_name": "Sentrin-specific protease 5", "gene_name": "SENP5", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17591783", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The intrinsic affinity between E2 and the Cys domain of E1 in ubiquitin-like modifications.", "journal": "Molecular cell", "date": "2007", "authors": "Wang J, Hu W, Cai S, Lee B, Song J, Chen Y", "reference": { "type": "PubMed", "id": "17643372", "url": "https://pubmed.ncbi.nlm.nih.gov/17643372" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBE0-1", "protein_name": "SUMO-activating enzyme subunit 1", "gene_name": "SAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBT2-1", "protein_name": "SUMO-activating enzyme subunit 2", "gene_name": "UBA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3V2-1", "protein_name": "RWD domain-containing protein 3", "gene_name": "RWDD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 235, "end_pos": 235, "sequence_org": "I", "sequence_mut": "A", "comment": "Strongly reduced interaction with UBE2I; when associated with A-238.", "evidence": [ { "database": "UniProtKB", "id": "Q9UBT2", "url": "https://www.uniprot.org/uniprotkb/Q9UBT2" }, { "database": "PubMed", "id": "17643372", "url": "https://pubmed.ncbi.nlm.nih.gov/17643372" } ], "uniprot_canonical_ac": "Q9UBT2-1" }, { "start_pos": 238, "end_pos": 238, "sequence_org": "I", "sequence_mut": "A", "comment": "Strongly reduced interaction with UBE2I; when associated with A-235.", "evidence": [ { "database": "UniProtKB", "id": "Q9UBT2", "url": "https://www.uniprot.org/uniprotkb/Q9UBT2" }, { "database": "PubMed", "id": "17643372", "url": "https://pubmed.ncbi.nlm.nih.gov/17643372" } ], "uniprot_canonical_ac": "Q9UBT2-1" } ], "record_id": "pubmed.17643372", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Ubiquitylation-independent degradation of Xeroderma pigmentosum group C protein is required for efficient nucleotide excision repair.", "journal": "Nucleic acids research", "date": "2007", "authors": "Wang QE, Praetorius-Ibba M, Zhu Q, El-Mahdy MA, Wani G, Zhao Q, Qin S, Patnaik S, Wani AA", "reference": { "type": "PubMed", "id": "17693435", "url": "https://pubmed.ncbi.nlm.nih.gov/17693435" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase 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"uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17693435", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"gene_name": "RARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06401-1", "protein_name": "Progesterone receptor", "gene_name": "PGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 294, "end_pos": 294, "sequence_org": "S", "sequence_mut": "A", "comment": "No effect on interaction with CUEDC2. Impaired progesterone-induced transcriptional activity. No CUEDC2- nor progestin-mediated protein degradation. No change in sumoylation; when associated with A-344 and A-345.", "evidence": [ { "database": "UniProtKB", "id": "P06401", "url": "https://www.uniprot.org/uniprotkb/P06401" }, { "database": "PubMed", "id": "17717077", "url": "https://pubmed.ncbi.nlm.nih.gov/17717077" }, { "database": "PubMed", "id": "17173941", "url": "https://pubmed.ncbi.nlm.nih.gov/17173941" }, { "database": "PubMed", "id": "10655479", "url": "https://pubmed.ncbi.nlm.nih.gov/10655479" } ], "uniprot_canonical_ac": "P06401-1" }, { "start_pos": 294, "end_pos": 294, "sequence_org": "S", "sequence_mut": "D", "comment": "Decreases protein stability and increases progesterone-induced transcriptional activity.", "evidence": [ { "database": "UniProtKB", "id": "P06401", "url": "https://www.uniprot.org/uniprotkb/P06401" }, { "database": "PubMed", "id": "17717077", "url": "https://pubmed.ncbi.nlm.nih.gov/17717077" }, { "database": "PubMed", "id": "17173941", "url": "https://pubmed.ncbi.nlm.nih.gov/17173941" }, { "database": "PubMed", "id": "10655479", "url": "https://pubmed.ncbi.nlm.nih.gov/10655479" } ], "uniprot_canonical_ac": "P06401-1" }, { "start_pos": 388, "end_pos": 388, "sequence_org": "K", "sequence_mut": "R", "comment": "Great loss of sumoylation; when associated with R-7. Completely abolishes sumoylation; when associated with R-7 and R-531. Loss of CUEDC2-mediated protein degradation. Increased ligand-dependent transcriptional activity.", "evidence": [ { "database": "UniProtKB", "id": "P06401", "url": "https://www.uniprot.org/uniprotkb/P06401" }, { "database": "PubMed", "id": "17020914", "url": "https://pubmed.ncbi.nlm.nih.gov/17020914" }, { "database": "PubMed", "id": "17717077", "url": "https://pubmed.ncbi.nlm.nih.gov/17717077" }, { "database": "PubMed", "id": "17347654", "url": "https://pubmed.ncbi.nlm.nih.gov/17347654" } ], "uniprot_canonical_ac": "P06401-1" } ], "phosphorylation": [ { "start_pos": 294, "end_pos": 294, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "Phosphoserine; by MAPK1", "evidence": [ { "database": "UniProtKB", "id": "P06401", "url": "https://www.uniprot.org/uniprotkb/P06401" }, { "database": "iPTMnet", "id": "P06401", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P06401" }, { "database": "PubMed", "id": "11110801", "url": "https://pubmed.ncbi.nlm.nih.gov/11110801" }, { "database": 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"kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "TOPORS functions as a SUMO-1 E3 ligase for chromatin-modifying proteins.", "journal": "Journal of proteome research", "date": "2007", "authors": "Pungaliya P, Kulkarni D, Park HJ, Marshall H, Zheng H, Lackland H, Saleem A, Rubin EH", "reference": { "type": "PubMed", "id": "17803295", "url": "https://pubmed.ncbi.nlm.nih.gov/17803295" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.17803295", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Role for KAP1 serine 824 phosphorylation and sumoylation/desumoylation switch in regulating KAP1-mediated transcriptional repression.", "journal": "The Journal of biological chemistry", "date": "2007", "authors": "Li X, Lee YK, Jeng JC, Yen Y, Schultz DC, Shih HM, Ann DK", "reference": { "type": "PubMed", "id": "17942393", "url": "https://pubmed.ncbi.nlm.nih.gov/17942393" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 306, "end_pos": 306, "sequence_org": "L", "sequence_mut": "P", "comment": "Disrupts the interaction with ZNF350 and amost completely relieves the transcription repressive effect of sumoylated TRIM28.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "17942393", "url": "https://pubmed.ncbi.nlm.nih.gov/17942393" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 554, "end_pos": 554, "sequence_org": "K", "sequence_mut": "R", "comment": "Moderately reduces sumoylation and repression. Abolishes both sumoylation and repression; when associated with R-575. Relieves the repressor activity on Dox-induced GADD45A transcription and 2-fold increase in phosphorylation at Ser-824; when associated with R-779 and R-804.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" }, { "database": "PubMed", "id": "17079232", "url": "https://pubmed.ncbi.nlm.nih.gov/17079232" }, { "database": "PubMed", "id": "17942393", "url": "https://pubmed.ncbi.nlm.nih.gov/17942393" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 779, "end_pos": 779, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes both sumoylation and repression; when associated with R-804. Relieves the repressor activity on Dox-induced GADD45A transcription and 2-fold increase in phosphorylation at Ser-824; when associated with R-554 and R-804.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" }, { "database": "PubMed", "id": "17079232", "url": "https://pubmed.ncbi.nlm.nih.gov/17079232" }, { "database": "PubMed", "id": "17942393", "url": "https://pubmed.ncbi.nlm.nih.gov/17942393" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 804, "end_pos": 804, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes both sumoylation and repression; when associated with R-779. Relieves the repressor activity on Dox-induced GADD45A transcription and 2-fold increase in phosphorylation at Ser-824; when associated with R-554 and R-779.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" }, { "database": "PubMed", "id": "17942393", "url": "https://pubmed.ncbi.nlm.nih.gov/17942393" }, { "database": "PubMed", "id": "17079232", "url": "https://pubmed.ncbi.nlm.nih.gov/17079232" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 824, "end_pos": 824, "sequence_org": "S", "sequence_mut": "A", "comment": "Suppresses Dox-induced CDKN1A/p21 promoter activation. No effect on sumoylation levels. Decreased sumoylation levels; when associated with D-440 and D-501.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "20424263", "url": "https://pubmed.ncbi.nlm.nih.gov/20424263" }, { "database": "PubMed", "id": "17942393", "url": "https://pubmed.ncbi.nlm.nih.gov/17942393" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 824, "end_pos": 824, "sequence_org": "S", "sequence_mut": "D", "comment": "Enhances Dox-induced CDKN1A/p21 promoter activation. 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"Molecular cell", "date": "2007", "authors": "Ivanov AV, Peng H, Yurchenko V, Yap KL, Negorev DG, Schultz DC, Psulkowski E, Fredericks WJ, White DE, Maul GG, Sadofsky MJ, Zhou MM, Rauscher FJ 3rd", "reference": { "type": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17019-1", "protein_name": "Zinc finger protein 708", "gene_name": "ZNF708", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQX6-1", "protein_name": "Zinc finger protein 331", "gene_name": "ZNF331", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SR6-1", "protein_name": "Zinc finger protein 382", "gene_name": "ZNF382", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TB69-1", "protein_name": "Zinc finger protein 519", "gene_name": "ZNF519", "tax_name": "Human" }, { 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"uniprot_canonical_ac": "Q7L2R6-1", "protein_name": "Zinc finger protein 765", "gene_name": "ZNF765", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q71UI9-1", "protein_name": "Histone H2A.V", "gene_name": "H2AZ2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04908-1", "protein_name": "Histone H2A type 1-B/E", "gene_name": "H2AC4; H2AC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P20671-1", "protein_name": "Histone H2A type 1-D", "gene_name": "H2AC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16777-1", "protein_name": "Histone H2A type 2-C", "gene_name": "H2AC20", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6FI13-1", "protein_name": "Histone H2A type 2-A", "gene_name": "H2AC18; H2AC19", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99878-1", "protein_name": "Histone H2A type 1-J", "gene_name": "H2AC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q0VGE8-1", "protein_name": "Zinc finger protein 816", "gene_name": "ZNF816", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q76KX8-1", "protein_name": "Zinc finger protein 534", "gene_name": "ZNF534", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NEM1-1", "protein_name": "Zinc finger protein 680", "gene_name": "ZNF680", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WXI9-1", "protein_name": "Transcriptional repressor p66-beta", "gene_name": "GATAD2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 554, "end_pos": 554, "sequence_org": "K", "sequence_mut": "R", "comment": "Moderately reduces sumoylation and repression. 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Loss of catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18488044", "url": "https://pubmed.ncbi.nlm.nih.gov/18488044" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" }, { "database": "PubMed", "id": "38172120", "url": "https://pubmed.ncbi.nlm.nih.gov/38172120" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 676, "end_pos": 676, "sequence_org": "K", "sequence_mut": "R", "comment": "Modestly reduces sumoylation and repression.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "17079232", "url": "https://pubmed.ncbi.nlm.nih.gov/17079232" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 750, "end_pos": 750, "sequence_org": "K", "sequence_mut": "R", "comment": "Some reduced sumoylation and repression.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 779, "end_pos": 779, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes both sumoylation and repression; when associated with R-804. Relieves the repressor activity on Dox-induced GADD45A transcription and 2-fold increase in phosphorylation at Ser-824; when associated with R-554 and R-804.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" }, { "database": "PubMed", "id": "17079232", "url": "https://pubmed.ncbi.nlm.nih.gov/17079232" }, { "database": "PubMed", "id": "17942393", "url": "https://pubmed.ncbi.nlm.nih.gov/17942393" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 804, "end_pos": 804, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes both sumoylation and repression; when associated with R-779. Relieves the repressor activity on Dox-induced GADD45A transcription and 2-fold increase in phosphorylation at Ser-824; when associated with R-554 and R-779.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" }, { "database": "PubMed", "id": "17942393", "url": "https://pubmed.ncbi.nlm.nih.gov/17942393" }, { "database": "PubMed", "id": "17079232", "url": "https://pubmed.ncbi.nlm.nih.gov/17079232" } ], "uniprot_canonical_ac": "Q13263-1" } ], "record_id": "pubmed.18082607", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 115 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], 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}, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMOylation modulates the transcription repressor function of RIP140.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Rytinki MM, Palvimo JJ", "reference": { "type": "PubMed", "id": "18211901", "url": "https://pubmed.ncbi.nlm.nih.gov/18211901" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": 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"uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", 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"uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18211901", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sumoylation is critical for DJ-1 to repress p53 transcriptional activity.", "journal": "FEBS letters", "date": "2008", "authors": "Fan J, Ren H, Fei E, Jia N, Ying Z, Jiang P, Wu M, Wang G", "reference": { "type": "PubMed", "id": "18339323", "url": "https://pubmed.ncbi.nlm.nih.gov/18339323" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18339323", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification of SUMO-dependent chromatin-associated transcriptional repression components by a genome-wide RNAi screen.", "journal": "Molecular cell", "date": "2008", "authors": "Stielow B, Sapetschnig A, Kruger I, Kunert N, Brehm A, Boutros M, Suske G", "reference": { "type": "PubMed", "id": "18374648", "url": "https://pubmed.ncbi.nlm.nih.gov/18374648" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small 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"FOXL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02447-1", "protein_name": "Transcription factor Sp3", "gene_name": "SP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00987-1", "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "MDM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18374648", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 18 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Conjugation of human topoisomerase 2 alpha with small ubiquitin-like modifiers 2/3 in response to topoisomerase inhibitors: cell cycle stage and chromosome domain specificity.", "journal": "Cancer research", "date": "2008", "authors": "Agostinho M, Santos V, Ferreira F, Costa R, Cardoso J, Pinheiro I, Rino J, Jaffray E, Hay RT, Ferreira J", "reference": { "type": "PubMed", "id": "18381449", "url": "https://pubmed.ncbi.nlm.nih.gov/18381449" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", 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"protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15392-1", "protein_name": "Baculoviral IAP repeat-containing protein 5", "gene_name": "BIRC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQS7-1", "protein_name": "Inner centromere protein", "gene_name": "INCENP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11387-1", "protein_name": "DNA topoisomerase 1", "gene_name": "TOP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GD4-1", "protein_name": "Aurora kinase B", "gene_name": "AURKB", "tax_name": 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"uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18381449", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 43 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15392-1", "protein_name": "Baculoviral IAP repeat-containing protein 5", "gene_name": "BIRC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQS7-1", "protein_name": "Inner centromere protein", "gene_name": "INCENP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11387-1", "protein_name": "DNA topoisomerase 1", "gene_name": "TOP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GD4-1", "protein_name": "Aurora kinase B", "gene_name": "AURKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12004-1", "protein_name": "DNA sliding clamp PCNA", "gene_name": "PCNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53HL2-1", "protein_name": "Borealin", "gene_name": "CDCA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase 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{ "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO conjugation to the matrix attachment region-binding protein, special AT-rich sequence-binding protein-1 (SATB1), targets SATB1 to promyelocytic nuclear bodies where it undergoes caspase cleavage.", "journal": "The Journal of biological chemistry", "date": "2008", "authors": "Tan JA, Sun Y, Song J, Chen Y, Krontiris TG, Durrin LK", "reference": { "type": "PubMed", "id": "18408014", "url": "https://pubmed.ncbi.nlm.nih.gov/18408014" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969R5-1", "protein_name": "Lethal(3)malignant brain tumor-like protein 2", "gene_name": "L3MBTL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13547-1", "protein_name": "Histone deacetylase 1", "gene_name": "HDAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", 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Loss of binding UBE2I. Loss of catalytic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18488044", "url": "https://pubmed.ncbi.nlm.nih.gov/18488044" }, { "database": "PubMed", "id": "18082607", "url": "https://pubmed.ncbi.nlm.nih.gov/18082607" }, { "database": "PubMed", "id": "38172120", "url": "https://pubmed.ncbi.nlm.nih.gov/38172120" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 653, "end_pos": 653, "sequence_org": "L", "sequence_mut": "A", "comment": "Greatly reduced sumoylation. Little further effect on sumoylation; when associated with A-668 and/or A-709.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18488044", "url": "https://pubmed.ncbi.nlm.nih.gov/18488044" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 668, "end_pos": 668, "sequence_org": "L", "sequence_mut": "A", "comment": "Little effect on sumoylation. Little further effect on sumoylation; when associated with A-653 and/or A-709.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18488044", "url": "https://pubmed.ncbi.nlm.nih.gov/18488044" } ], "uniprot_canonical_ac": "Q13263-1" }, { "start_pos": 709, "end_pos": 709, "sequence_org": "L", "sequence_mut": "A", "comment": "Greatly reduced sumoylation. Little further effect on sumoylation; when associated with A-653 and/or A-668.", "evidence": [ { "database": "UniProtKB", "id": "Q13263", "url": "https://www.uniprot.org/uniprotkb/Q13263" }, { "database": "PubMed", "id": "18488044", "url": "https://pubmed.ncbi.nlm.nih.gov/18488044" } ], "uniprot_canonical_ac": "Q13263-1" } ], "record_id": "pubmed.18488044", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanism and consequences for paralog-specific sumoylation of ubiquitin-specific protease 25.", "journal": "Molecular cell", "date": "2008", "authors": "Meulmeester E, Kunze M, Hsiao HH, Urlaub H, Melchior F", "reference": { "type": "PubMed", "id": "18538659", "url": "https://pubmed.ncbi.nlm.nih.gov/18538659" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UHP3-2", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 25", "gene_name": "USP25", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 33, "end_pos": 33, "sequence_org": "I", "sequence_mut": "A", "comment": "Impaired interaction with USP25; when associated with A-34.", "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" }, { "database": "PubMed", "id": "18538659", "url": "https://pubmed.ncbi.nlm.nih.gov/18538659" } ], "uniprot_canonical_ac": "P55854-1" }, { "start_pos": 34, "end_pos": 34, "sequence_org": "K", "sequence_mut": "A", "comment": "Impaired interaction with USP25; when associated with A-33.", "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" }, { "database": "PubMed", "id": "18538659", "url": "https://pubmed.ncbi.nlm.nih.gov/18538659" } ], "uniprot_canonical_ac": "P55854-1" }, { "start_pos": 91, "end_pos": 91, "sequence_org": "V", "sequence_mut": "A", "comment": "No interaction with SUMO3; when associated with A-92.", "evidence": [ { "database": "UniProtKB", "id": "Q9UHP3", "url": "https://www.uniprot.org/uniprotkb/Q9UHP3" }, { "database": "PubMed", "id": "18538659", "url": "https://pubmed.ncbi.nlm.nih.gov/18538659" } ], "uniprot_canonical_ac": "Q9UHP3-2" }, { "start_pos": 92, "end_pos": 92, "sequence_org": "I", "sequence_mut": "A", "comment": "No interaction with SUMO3; when associated with A-91.", "evidence": [ { "database": "UniProtKB", "id": "Q9UHP3", "url": "https://www.uniprot.org/uniprotkb/Q9UHP3" }, { "database": "PubMed", "id": "18538659", "url": "https://pubmed.ncbi.nlm.nih.gov/18538659" } ], "uniprot_canonical_ac": "Q9UHP3-2" }, { "start_pos": 99, "end_pos": 99, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes sumoylation. Decreased enzymatic activity.", "evidence": [ { "database": "UniProtKB", "id": "Q9UHP3", "url": "https://www.uniprot.org/uniprotkb/Q9UHP3" }, { "database": "PubMed", "id": "19440361", "url": "https://pubmed.ncbi.nlm.nih.gov/19440361" }, { "database": "PubMed", "id": "18538659", "url": "https://pubmed.ncbi.nlm.nih.gov/18538659" } ], "uniprot_canonical_ac": "Q9UHP3-2" } ], "record_id": "pubmed.18538659", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO-modified Sp3 represses transcription by provoking local heterochromatic gene silencing.", "journal": "EMBO reports", "date": "2008", "authors": "Stielow B, Sapetschnig A, Wink C, Kruger I, Suske G", "reference": { "type": "PubMed", "id": "18617891", "url": "https://pubmed.ncbi.nlm.nih.gov/18617891" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92481-1", "protein_name": "Transcription factor AP-2-beta", "gene_name": "TFAP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13330-1", "protein_name": "Metastasis-associated protein MTA1", "gene_name": "MTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92754-1", "protein_name": "Transcription factor AP-2 gamma", "gene_name": "TFAP2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14526-1", "protein_name": "Hypermethylated in cancer 1 protein", "gene_name": "HIC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75030-1", "protein_name": "Microphthalmia-associated transcription factor", "gene_name": "MITF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58012-1", "protein_name": "Forkhead box protein L2", "gene_name": "FOXL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02447-1", "protein_name": "Transcription factor Sp3", "gene_name": "SP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00987-1", "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "MDM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18617891", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 18 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO1 modification of NF-kappaB2/p100 is essential for stimuli-induced p100 phosphorylation and processing.", "journal": "EMBO reports", "date": "2008", "authors": "Vatsyayan J, Qing G, Xiao G, Hu J", "reference": { "type": "PubMed", "id": "18617892", "url": "https://pubmed.ncbi.nlm.nih.gov/18617892" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18617892", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Histone deacetylase 7 promotes PML sumoylation and is essential for PML nuclear body formation.", "journal": "Molecular and cellular biology", "date": "2008", "authors": "Gao C, Ho CC, Reineke E, Lam M, Cheng X, Stanya KJ, Liu Y, Chakraborty S, Shih HM, Kao HY", "reference": { "type": "PubMed", "id": "18625722", "url": "https://pubmed.ncbi.nlm.nih.gov/18625722" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes 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"tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin 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"MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18625722", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The polycomb repressive complex 2 is a potential target of SUMO modifications.", "journal": "PloS one", "date": "2008", "authors": "Riising EM, Boggio R, Chiocca S, Helin K, Pasini D", "reference": { "type": "PubMed", "id": "18628979", "url": "https://pubmed.ncbi.nlm.nih.gov/18628979" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969R5-1", "protein_name": "Lethal(3)malignant brain tumor-like protein 2", "gene_name": "L3MBTL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13547-1", "protein_name": "Histone deacetylase 1", "gene_name": "HDAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15910-1", "protein_name": "Histone-lysine N-methyltransferase EZH2", "gene_name": "EZH2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01826-1", "protein_name": "DNA-binding protein SATB1", "gene_name": "SATB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96006-1", "protein_name": "E3 SUMO-protein ligase ZBED1", "gene_name": "ZBED1", "tax_name": 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conserved through evolution.", "journal": "Journal of proteome research", "date": "2008", "authors": "Matic I, Macek B, Hilger M, Walther TC, Mann M", "reference": { "type": "PubMed", "id": "18707152", "url": "https://pubmed.ncbi.nlm.nih.gov/18707152" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 2, "end_pos": 2, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Ser", "comment": "", "evidence": 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"uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", 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"RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.18708356", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "RanBP2 and SENP3 function in a mitotic SUMO2/3 conjugation-deconjugation cycle on Borealin.", "journal": "Molecular biology of the cell", "date": "2009", "authors": "Klein UR, Haindl M, Nigg EA, Muller S", "reference": { "type": "PubMed", "id": "18946085", "url": "https://pubmed.ncbi.nlm.nih.gov/18946085" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O14965-1", "protein_name": "Aurora kinase A", "gene_name": "AURKA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11388-1", "protein_name": "DNA topoisomerase 2-alpha", "gene_name": "TOP2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H4L4-1", "protein_name": "Sentrin-specific protease 3", "gene_name": "SENP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15392-1", "protein_name": "Baculoviral IAP repeat-containing protein 5", "gene_name": "BIRC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NQS7-1", "protein_name": "Inner centromere protein", "gene_name": "INCENP", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11387-1", "protein_name": "DNA topoisomerase 1", "gene_name": "TOP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GD4-1", "protein_name": "Aurora kinase B", "gene_name": "AURKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12004-1", "protein_name": "DNA sliding clamp PCNA", "gene_name": "PCNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53HL2-1", "protein_name": "Borealin", "gene_name": "CDCA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46060-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02880-1", "protein_name": "DNA topoisomerase 2-beta", "gene_name": "TOP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 26, "end_pos": 26, "sequence_org": "K", "sequence_mut": "R", "comment": "Fails to exhibit normal localization to the nucleolus in interphase depleted cells.", "evidence": [ { "database": "UniProtKB", "id": "Q53HL2", "url": "https://www.uniprot.org/uniprotkb/Q53HL2" }, { "database": "PubMed", "id": "18946085", "url": "https://pubmed.ncbi.nlm.nih.gov/18946085" } ], "uniprot_canonical_ac": "Q53HL2-1" } ], "record_id": "pubmed.18946085", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 44 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMOylation of RORalpha potentiates transcriptional activation function.", "journal": "Biochemical and biophysical research communications", "date": "2009", "authors": "Hwang EJ, Lee JM, Jeong J, Park JH, Yang Y, Lim JS, Kim JH, Baek SH, Kim KI", "reference": { "type": "PubMed", "id": "19041634", "url": "https://pubmed.ncbi.nlm.nih.gov/19041634" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10276-1", "protein_name": "Retinoic acid receptor alpha", "gene_name": "RARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06401-1", "protein_name": "Progesterone receptor", "gene_name": "PGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Physical and functional interaction between DDB and XPA in nucleotide excision repair.", "journal": "Nucleic acids research", "date": "2009", "authors": "Wakasugi M, Kasashima H, Fukase Y, Imura M, Imai R, Yamada S, Cleaver JE, Matsunaga T", "reference": { "type": "PubMed", "id": "19056823", "url": "https://pubmed.ncbi.nlm.nih.gov/19056823" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54727-1", "protein_name": "Lysine-specific demethylase RAD23B", "gene_name": "RAD23B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13888-1", "protein_name": "General transcription factor IIH subunit 2", "gene_name": "GTF2H2C_2; GTF2H2C; GTF2H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92759-1", "protein_name": "General transcription factor IIH subunit 4", "gene_name": "GTF2H4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19447-1", "protein_name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "gene_name": "ERCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28715-1", "protein_name": "DNA excision repair protein ERCC-5", "gene_name": "ERCC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UGN5-1", "protein_name": "Poly [ADP-ribose] polymerase 2", "gene_name": "PARP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZYL4-1", "protein_name": "General transcription factor IIH subunit 5", "gene_name": "GTF2H5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07992-1", "protein_name": "DNA excision repair protein ERCC-1", "gene_name": "ERCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16531-1", "protein_name": "DNA damage-binding protein 1", "gene_name": "DDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WJ1-1", "protein_name": "ATP-dependent chromatin remodeler CHD1L", "gene_name": "CHD1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32780-1", "protein_name": "General transcription factor IIH subunit 1", "gene_name": "GTF2H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13889-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "GTF2H3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92466-1", "protein_name": "DNA damage-binding protein 2", "gene_name": "DDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62877-1", "protein_name": "E3 ubiquitin-protein ligase RBX1", "gene_name": "RBX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18074-1", "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "ERCC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51948-1", "protein_name": "CDK-activating kinase assembly factor MAT1", "gene_name": "MNAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51946-1", "protein_name": "Cyclin-H", "gene_name": "CCNH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54725-1", "protein_name": "Lysine-specific demethylase RAD23A", "gene_name": "RAD23A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZNA4-1", "protein_name": "E3 ubiquitin-protein ligase Arkadia", "gene_name": "RNF111", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13619-1", "protein_name": "Cullin-4A", "gene_name": "CUL4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13620-2", "protein_name": "Cullin-4B", "gene_name": "CUL4B", "tax_name": "Human" }, { 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"protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19056823", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 43 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3V2-1", "protein_name": "RWD domain-containing protein 3", "gene_name": "RWDD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19107418", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 7 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Abdel-Hafiz H, Dudevoir ML, Horwitz KB", "reference": { "type": "PubMed", "id": "19211567", "url": "https://pubmed.ncbi.nlm.nih.gov/19211567" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10276-1", "protein_name": "Retinoic acid receptor alpha", "gene_name": "RARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06401-1", "protein_name": "Progesterone receptor", "gene_name": "PGR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35398-2", "protein_name": "Nuclear receptor ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19211567", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 24 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Novel proteomics strategy brings insight into the prevalence of SUMO-2 target sites.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Blomster HA, Hietakangas V, Wu J, Kouvonen P, Hautaniemi S, Sistonen L", "reference": { "type": "PubMed", "id": "19240082", "url": "https://pubmed.ncbi.nlm.nih.gov/19240082" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19240082", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A novel mechanism whereby BRCA1/1a/1b fine tunes the dynamic complex interplay between SUMO-dependent/independent activities of Ubc9 on E2-induced ERalpha activation/repression and degradation in breast cancer cells.", "journal": "International journal of oncology", "date": "2009", "authors": "Xu J, Watkins T, Reddy A, Reddy ES, Rao VN", "reference": { "type": "PubMed", "id": "19287951", "url": "https://pubmed.ncbi.nlm.nih.gov/19287951" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": 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"uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19287951", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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}, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Adenosine signaling mediates SUMO-1 modification of IkappaBalpha during hypoxia and reoxygenation.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Liu Q, Li J, Khoury J, Colgan SP, Ibla JC", "reference": { "type": "PubMed", "id": "19297320", "url": 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"reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19297320", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Conformational transition associated with E1-E2 interaction in small ubiquitin-like modifications.", "journal": "The Journal of biological chemistry", "date": "2009", "authors": "Wang J, Lee B, Cai S, Fukui L, Hu W, Chen Y", "reference": { "type": "PubMed", "id": "19443651", "url": "https://pubmed.ncbi.nlm.nih.gov/19443651" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBE0-1", "protein_name": "SUMO-activating enzyme subunit 1", "gene_name": "SAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBT2-1", "protein_name": "SUMO-activating enzyme subunit 2", "gene_name": "UBA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y3V2-1", "protein_name": "RWD domain-containing protein 3", "gene_name": "RWDD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": 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"Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.", "journal": "Molecular & cellular proteomics : MCP", "date": "2009", "authors": "Matafora V, D'Amato A, Mori S, Blasi F, Bachi A", "reference": { "type": "PubMed", "id": "19596686", "url": "https://pubmed.ncbi.nlm.nih.gov/19596686" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": 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"Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance 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"Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96GD4-1", "protein_name": "Aurora kinase B", "gene_name": "AURKB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12004-1", "protein_name": "DNA sliding clamp PCNA", "gene_name": "PCNA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q53HL2-1", "protein_name": "Borealin", "gene_name": "CDCA8", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46060-1", "protein_name": "Ran GTPase-activating protein 1", "gene_name": "RANGAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02880-1", "protein_name": "DNA topoisomerase 2-beta", "gene_name": "TOP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y2X3-1", "protein_name": "Nucleolar protein 58", "gene_name": "NOP58", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61978-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein K", "gene_name": "HNRNPK", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19596686", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 111 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome 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"gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19615980", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sumoylation of poly(ADP-ribose) polymerase 1 inhibits its acetylation and restrains transcriptional coactivator function.", "journal": "FASEB journal : official publication of the Federation of American Societies for Experimental Biology", "date": "2009", "authors": "Messner S, Schuermann D, Altmeyer M, Kassner I, Schmidt D, Schar P, Muller S, Hottiger MO", "reference": { "type": "PubMed", "id": "19622798", "url": "https://pubmed.ncbi.nlm.nih.gov/19622798" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": 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"protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex 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{ "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1.", "journal": "Science (New York, N.Y.)", "date": "2009", "authors": "Ahel D, Horejsi Z, Wiechens N, Polo SE, Garcia-Wilson E, Ahel I, Flynn H, Skehel M, West SC, Jackson SP, Owen-Hughes T, Boulton SJ", "reference": { "type": "PubMed", "id": "19661379", "url": "https://pubmed.ncbi.nlm.nih.gov/19661379" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54727-1", "protein_name": "Lysine-specific demethylase RAD23B", "gene_name": "RAD23B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13888-1", "protein_name": "General transcription factor IIH subunit 2", "gene_name": "GTF2H2C_2; GTF2H2C; GTF2H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92759-1", "protein_name": "General transcription factor IIH subunit 4", "gene_name": "GTF2H4", "tax_name": "Human" }, { 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO-dependent regulation of centrin-2.", "journal": "Journal of cell science", "date": "2009", "authors": "Klein UR, Nigg EA", "reference": { "type": "PubMed", "id": "19706679", "url": "https://pubmed.ncbi.nlm.nih.gov/19706679" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", 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"protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small 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"tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Molecular insights into the recruitment of TFIIH to sites of DNA damage.", "journal": "The EMBO journal", "date": "2009", "authors": "Oksenych V, Bernardes de Jesus B, Zhovmer A, Egly JM, Coin F", "reference": { "type": "PubMed", "id": "19713942", "url": "https://pubmed.ncbi.nlm.nih.gov/19713942" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54727-1", "protein_name": "Lysine-specific demethylase RAD23B", "gene_name": "RAD23B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13888-1", "protein_name": "General transcription factor IIH subunit 2", "gene_name": "GTF2H2C_2; GTF2H2C; GTF2H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92759-1", "protein_name": "General transcription factor IIH subunit 4", 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"uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZNA4-1", "protein_name": "E3 ubiquitin-protein ligase Arkadia", "gene_name": "RNF111", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13619-1", "protein_name": "Cullin-4A", "gene_name": "CUL4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13620-2", "protein_name": "Cullin-4B", "gene_name": "CUL4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q70EL2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 45", "gene_name": "USP45", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50613-1", "protein_name": "Cyclin-dependent kinase 7", "gene_name": "CDK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92889-1", "protein_name": "DNA repair endonuclease XPF", "gene_name": "ERCC4", "tax_name": "Human" }, { 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"glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sumoylation of forkhead L2 by Ubc9 is required for its activity as a transcriptional repressor of the Steroidogenic Acute Regulatory gene.", "journal": "Cellular signalling", "date": "2009", "authors": "Kuo FT, Bentsi-Barnes IK, Barlow GM, Bae J, Pisarska MD", "reference": { "type": "PubMed", "id": "19744555", "url": "https://pubmed.ncbi.nlm.nih.gov/19744555" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" 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"protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02447-1", "protein_name": "Transcription factor Sp3", "gene_name": "SP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00987-1", "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "MDM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 25, "end_pos": 25, "sequence_org": "K", "sequence_mut": "R", "comment": "Results in reduced sumoylation. Loss of transcriptional repression activity.", "evidence": [ { "database": "UniProtKB", "id": "P58012", "url": "https://www.uniprot.org/uniprotkb/P58012" }, { "database": "PubMed", "id": "19744555", "url": "https://pubmed.ncbi.nlm.nih.gov/19744555" } ], "uniprot_canonical_ac": "P58012-1" } ], "record_id": "pubmed.19744555", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 18 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "PARP-1 transcriptional activity is regulated by sumoylation upon heat shock.", "journal": "The EMBO journal", "date": "2009", "authors": "Martin N, Schwamborn K, Schreiber V, Werner A, Guillier C, Zhang XD, Bischof O, Seeler JS, Dejean A", "reference": { "type": "PubMed", "id": "19779455", "url": "https://pubmed.ncbi.nlm.nih.gov/19779455" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": 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"uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9QZS2-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "Rnf4", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78317-1", "protein_name": "E3 ubiquitin-protein ligase RNF4", "gene_name": "RNF4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", 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"uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19779455", "abstract": "", "glycosylation": [], 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"SUMOylation of human peroxisome proliferator-activated receptor alpha inhibits its trans-activity through the recruitment of the nuclear corepressor NCoR.", "journal": "The Journal of biological chemistry", "date": "2010", "authors": "Pourcet B, Pineda-Torra I, Derudas B, Staels B, Glineur C", "reference": { "type": "PubMed", "id": "19955185", "url": "https://pubmed.ncbi.nlm.nih.gov/19955185" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10276-1", "protein_name": "Retinoic acid receptor alpha", "gene_name": "RARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { 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ROR-alpha", "gene_name": "RORA", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13285-1", "protein_name": "Steroidogenic factor 1", "gene_name": "NR5A1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10828-1", "protein_name": "Thyroid hormone receptor beta", "gene_name": "THRB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19955185", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], 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"uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.19956565", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Sumoylation of p68 and p72 RNA helicases affects protein stability and transactivation potential.", "journal": "Biochemistry", "date": "2010", "authors": "Mooney SM, Grande JP, Salisbury JL, Janknecht R", "reference": { "type": "PubMed", "id": "19995069", "url": "https://pubmed.ncbi.nlm.nih.gov/19995069" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { 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"protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 129, "end_pos": 129, "sequence_org": "K", "sequence_mut": "R", "comment": "Impaired sumoylation and decreased stability. Impairs interaction with HDAC1, but not with HDAC2, nor HDAC3. No effect on EP300-, ESR1-, DDX5- and YAP1-binding.", "evidence": [ { "database": "UniProtKB", "id": "Q92841", "url": "https://www.uniprot.org/uniprotkb/Q92841" }, { "database": "PubMed", "id": "19995069", "url": "https://pubmed.ncbi.nlm.nih.gov/19995069" }, { "database": "PubMed", "id": "24581491", "url": "https://pubmed.ncbi.nlm.nih.gov/24581491" } ], "uniprot_canonical_ac": "Q92841-4" }, { "start_pos": 53, "end_pos": 53, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes sumoylation, abolishes interaction with HDAC1, increases TP53 coactivation and promotes polyubiquitination.", "evidence": [ { "database": "UniProtKB", "id": "P17844", "url": "https://www.uniprot.org/uniprotkb/P17844" }, { "database": "PubMed", "id": "19995069", "url": "https://pubmed.ncbi.nlm.nih.gov/19995069" }, { "database": "PubMed", "id": "17369852", "url": "https://pubmed.ncbi.nlm.nih.gov/17369852" } ], "uniprot_canonical_ac": "P17844-1" } ], "record_id": "pubmed.19995069", "abstract": "", 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PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20016594", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.", "journal": "Nature", "date": "2009", "authors": "Galanty Y, Belotserkovskaya R, Coates J, Polo S, Miller KM, Jackson SP", "reference": { "type": "PubMed", "id": "20016603", "url": "https://pubmed.ncbi.nlm.nih.gov/20016603" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92993-1", "protein_name": "Histone acetyltransferase KAT5", "gene_name": "KAT5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92481-1", "protein_name": "Transcription factor AP-2-beta", "gene_name": "TFAP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13330-1", "protein_name": "Metastasis-associated protein MTA1", "gene_name": "MTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92754-1", "protein_name": "Transcription factor AP-2 gamma", "gene_name": "TFAP2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14526-1", "protein_name": "Hypermethylated in cancer 1 protein", "gene_name": "HIC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75030-1", "protein_name": "Microphthalmia-associated transcription factor", "gene_name": "MITF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04323-1", "protein_name": "UBX domain-containing protein 1", "gene_name": "UBXN1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60934-1", "protein_name": "Nibrin", "gene_name": "NBN", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92560-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase BAP1", "gene_name": "BAP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14191-1", "protein_name": "Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN", "gene_name": "WRN", "tax_name": "Human" }, { "uniprot_canonical_ac": "O76064-1", "protein_name": "E3 ubiquitin-protein ligase RNF8", "gene_name": "RNF8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "O94953-1", "protein_name": "Lysine-specific demethylase 4B", "gene_name": "KDM4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MF7-1", "protein_name": "E3 SUMO-protein ligase NSE2", "gene_name": "NSMCE2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WV22-1", "protein_name": "Non-structural maintenance of chromosomes element 1 homolog", "gene_name": "NSMCE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58012-1", "protein_name": "Forkhead box protein L2", "gene_name": "FOXL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16695-1", "protein_name": "Histone H3.1t", "gene_name": "H3-4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P46736-1", "protein_name": "Lys-63-specific deubiquitinase BRCC36", "gene_name": "BRCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96RL1-1", "protein_name": "BRCA1-A complex subunit RAP80", "gene_name": "UIMC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6UWZ7-1", "protein_name": "BRCA1-A complex subunit Abraxas 1", "gene_name": "ABRAXAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUI4-1", "protein_name": "Histone deacetylase 7", "gene_name": "HDAC7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P53041-1", "protein_name": "Serine/threonine-protein phosphatase 5", "gene_name": "PPP5C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13426-1", "protein_name": "DNA repair protein XRCC4", "gene_name": "XRCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23497-1", "protein_name": "Nuclear autoantigen Sp-100", "gene_name": "SP100", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16778-1", "protein_name": "Histone H2B type 2-E", "gene_name": "H2BC21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62807-1", "protein_name": "Histone H2B type 1-C/E/F/G/I", "gene_name": "H2BC10; H2BC4; H2BC6; H2BC7; H2BC8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96028-1", "protein_name": "Histone-lysine N-methyltransferase NSD2", "gene_name": "NSD2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49959-1", "protein_name": "Double-strand break repair protein MRE11", "gene_name": "MRE11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00167-1", "protein_name": "Protein phosphatase EYA2", "gene_name": "EYA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99504-1", "protein_name": "Protein phosphatase EYA3", "gene_name": "EYA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P45983-1", "protein_name": "Mitogen-activated protein kinase 8", "gene_name": "MAPK8", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60264-1", "protein_name": "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "gene_name": "SMARCA5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99728-1", "protein_name": "BRCA1-associated RING domain protein 1", "gene_name": "BARD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NWV8-1", "protein_name": "BRISC and BRCA1-A complex member 1", "gene_name": "BABAM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXR7-2", "protein_name": "BRISC and BRCA1-A complex member 2", "gene_name": "BABAM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIG0-1", "protein_name": "Tyrosine-protein kinase BAZ1B", "gene_name": "BAZ1B", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P16104-1", "protein_name": "Histone H2AX", "gene_name": "H2AX", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "P33778-1", "protein_name": "Histone H2B type 1-B", "gene_name": "H2BC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58876-1", "protein_name": "Histone H2B type 1-D", "gene_name": "H2BC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96A08-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2BC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23527-1", "protein_name": "Histone H2B type 1-O", "gene_name": "H2BC17", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75164-1", "protein_name": "Lysine-specific demethylase 4A", "gene_name": "KDM4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60814-1", "protein_name": "Histone H2B type 1-K", "gene_name": "H2BC12", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q93079-1", "protein_name": "Histone H2B type 1-H", "gene_name": "H2BC9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99879-1", "protein_name": "Histone H2B type 1-M", "gene_name": "H2BC14", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92878-1", "protein_name": "DNA repair protein RAD50", "gene_name": "RAD50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02447-1", "protein_name": "Transcription factor Sp3", "gene_name": "SP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95677-1", "protein_name": "Protein phosphatase EYA4", "gene_name": "EYA4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99502-1", "protein_name": "Protein phosphatase EYA1", "gene_name": "EYA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06899-1", "protein_name": "Histone H2B type 1-J", "gene_name": "H2BC11", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57053-1", "protein_name": "Histone H2B type F-S", "gene_name": "H2BC12L", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N257-1", "protein_name": "Histone H2B type 3-B", "gene_name": "H2BC26", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99877-1", "protein_name": "Histone H2B type 1-N", "gene_name": "H2BC15", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99880-1", "protein_name": "Histone H2B type 1-L", "gene_name": "H2BC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00213-1", "protein_name": "Amyloid beta precursor protein binding family B member 1", "gene_name": "APBB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P00519-1", "protein_name": "Tyrosine-protein kinase ABL1", "gene_name": "ABL1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00987-1", "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "MDM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96017-1", "protein_name": "Serine/threonine-protein kinase Chk2", "gene_name": "CHEK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13315-1", "protein_name": "Serine-protein kinase ATM", "gene_name": "ATM", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 4, "end_pos": 4, "kinase_uniprot_canonical_ac": "Q8N2W9-1", "kinase_gene_name": "PIAS4", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15927" }, { "database": "PubMed", "id": "20016603", "url": "https://pubmed.ncbi.nlm.nih.gov/20016603" } ], "site_lbl": "Ser4", "uniprot_canonical_ac": "P15927-1" }, { "start_pos": 8, "end_pos": 8, "kinase_uniprot_canonical_ac": "Q8N2W9-1", "kinase_gene_name": "PIAS4", "residue": "Ser", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "P15927", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/P15927" }, { "database": "PubMed", "id": "20016603", "url": "https://pubmed.ncbi.nlm.nih.gov/20016603" } ], "site_lbl": "Ser8", "uniprot_canonical_ac": "P15927-1" } ], "record_id": "pubmed.20016603", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 135 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "A role for non-covalent SUMO interaction motifs in Pc2/CBX4 E3 activity.", "journal": "PloS one", "date": "2010", "authors": "Merrill JC, Melhuish TA, Kagey MH, Yang SH, Sharrocks AD, Wotton D", "reference": { "type": "PubMed", "id": "20098713", "url": "https://pubmed.ncbi.nlm.nih.gov/20098713" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969R5-1", "protein_name": "Lethal(3)malignant brain tumor-like protein 2", "gene_name": "L3MBTL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", "protein_name": "Parkinson disease protein 7", "gene_name": "PARK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y618-1", "protein_name": "Nuclear receptor corepressor 2", "gene_name": "NCOR2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13547-1", "protein_name": "Histone deacetylase 1", "gene_name": "HDAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969V6-1", "protein_name": "Myocardin-related transcription factor A", "gene_name": "MRTFA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92841-4", "protein_name": "Probable ATP-dependent RNA helicase DDX17", "gene_name": "DDX17", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13263-1", "protein_name": "Transcription intermediary factor 1-beta", "gene_name": "TRIM28", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01826-1", "protein_name": "DNA-binding protein SATB1", "gene_name": "SATB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P17844-1", "protein_name": "Probable ATP-dependent RNA helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96006-1", "protein_name": "E3 SUMO-protein ligase ZBED1", "gene_name": "ZBED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P45973-1", "protein_name": "Chromobox protein homolog 5", "gene_name": "CBX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12873-1", "protein_name": "ATP-dependent chromatin remodeler CHD3", "gene_name": "CHD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92769-1", "protein_name": "Histone deacetylase 2", "gene_name": "HDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPW6-1", "protein_name": "DNA-binding protein SATB2", "gene_name": "SATB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20098713", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 80 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "GPS2-dependent corepressor/SUMO pathways govern anti-inflammatory actions of LRH-1 and LXRbeta in the hepatic acute phase response.", "journal": "Genes & development", "date": "2010", "authors": "Venteclef N, Jakobsson T, Ehrlund A, Damdimopoulos A, Mikkonen L, Ellis E, Nilsson LM, Parini P, Janne OA, Gustafsson JA, Steffensen KR, Treuter E", "reference": { "type": "PubMed", "id": "20159957", "url": "https://pubmed.ncbi.nlm.nih.gov/20159957" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04150-1", "protein_name": "Glucocorticoid receptor", "gene_name": "NR3C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10276-1", "protein_name": "Retinoic acid receptor alpha", "gene_name": "RARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37231-1", "protein_name": "Peroxisome proliferator-activated receptor gamma", "gene_name": "PPARG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q07869-1", "protein_name": "Peroxisome proliferator-activated receptor alpha", "gene_name": "PPARA", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19793-1", "protein_name": "Retinoic acid receptor RXR-alpha", "gene_name": "RXRA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q921N8-1", "protein_name": "G protein pathway suppressor 2", "gene_name": "Gps2", "tax_name": "Mouse" }, { "uniprot_canonical_ac": "Q13227-1", "protein_name": "G protein pathway suppressor 2", "gene_name": "GPS2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00482-1", "protein_name": "Nuclear receptor subfamily 5 group A member 2", "gene_name": "NR5A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55055-1", "protein_name": "Oxysterols receptor LXR-beta", "gene_name": "NR1H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P03372-1", "protein_name": "Estrogen receptor", "gene_name": "ESR1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small 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"uniprot_canonical_ac": "P11473-1", "protein_name": "Vitamin D3 receptor", "gene_name": "VDR", "tax_name": "Human" }, { "uniprot_canonical_ac": "P08235-1", "protein_name": "Mineralocorticoid receptor", "gene_name": "NR3C2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P13056-1", "protein_name": "Nuclear receptor subfamily 2 group C member 1", "gene_name": "NR2C1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43354-1", "protein_name": "Nuclear receptor subfamily 4 group A member 2", "gene_name": "NR4A2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P10275-1", "protein_name": "Androgen receptor", "gene_name": "AR", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 61, "end_pos": 94, "sequence_org": "SLEETKEQILKLEEKLLALQEEKHQLFLQLKKVL", "sequence_mut": "", "comment": "Abolishes interaction with sumoylated NR1H2 and NR5A2 proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q13227", "url": "https://www.uniprot.org/uniprotkb/Q13227" }, { "database": "PubMed", "id": "20159957", "url": "https://pubmed.ncbi.nlm.nih.gov/20159957" } ], "uniprot_canonical_ac": "Q13227-1" }, { "start_pos": 69, "end_pos": 70, "sequence_org": "IL", "sequence_mut": "AA", "comment": "Weakly affects interaction with sumoylated NR1H2 and NR5A2 proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q13227", "url": "https://www.uniprot.org/uniprotkb/Q13227" }, { "database": "PubMed", "id": "20159957", "url": "https://pubmed.ncbi.nlm.nih.gov/20159957" } ], "uniprot_canonical_ac": "Q13227-1" }, { "start_pos": 76, "end_pos": 79, "sequence_org": "LLAL", "sequence_mut": "RRAR", "comment": "Weakly affects interaction with sumoylated NR1H2 and NR5A2 proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q13227", "url": "https://www.uniprot.org/uniprotkb/Q13227" }, { "database": "PubMed", "id": "20159957", "url": "https://pubmed.ncbi.nlm.nih.gov/20159957" } ], "uniprot_canonical_ac": "Q13227-1" }, { "start_pos": 86, "end_pos": 90, "sequence_org": "LFLQL", "sequence_mut": "RFRQR", "comment": "Weakly affects interaction with sumoylated NR1H2 and NR5A2 proteins.", "evidence": [ { "database": "UniProtKB", "id": "Q13227", "url": "https://www.uniprot.org/uniprotkb/Q13227" }, { "database": "PubMed", "id": "20159957", "url": "https://pubmed.ncbi.nlm.nih.gov/20159957" } ], "uniprot_canonical_ac": "Q13227-1" }, { "start_pos": 270, "end_pos": 270, "sequence_org": "K", "sequence_mut": "R", "comment": "Impaired ability to act as an anti-inflammatory role during the hepatic acute phase response.", "evidence": [ { "database": "UniProtKB", "id": "O00482", "url": "https://www.uniprot.org/uniprotkb/O00482" }, { "database": "PubMed", "id": "20159957", "url": "https://pubmed.ncbi.nlm.nih.gov/20159957" } ], "uniprot_canonical_ac": "O00482-1" }, { "start_pos": 409, "end_pos": 409, "sequence_org": "K", "sequence_mut": "R", "comment": "Impaired ability to act as an anti-inflammatory role during the hepatic acute phase response; when associated with R-447.", "evidence": [ { "database": "UniProtKB", "id": "P55055", "url": "https://www.uniprot.org/uniprotkb/P55055" }, { "database": "PubMed", "id": "20159957", "url": "https://pubmed.ncbi.nlm.nih.gov/20159957" } ], "uniprot_canonical_ac": "P55055-1" }, { "start_pos": 447, "end_pos": 447, "sequence_org": "K", "sequence_mut": "R", "comment": "Impaired ability to act as an anti-inflammatory role during the hepatic acute phase response; when associated with R-409.", "evidence": [ { "database": 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"Active site remodelling accompanies thioester bond formation in the SUMO E1.", "journal": "Nature", "date": "2010", "authors": "Olsen SK, Capili AD, Lu X, Tan DS, Lima CD", "reference": { "type": "PubMed", "id": "20164921", "url": "https://pubmed.ncbi.nlm.nih.gov/20164921" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBE0-1", "protein_name": "SUMO-activating enzyme subunit 1", "gene_name": "SAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBT2-1", "protein_name": "SUMO-activating enzyme subunit 2", "gene_name": "UBA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": 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"o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The SUMO E3 ligase activity of Pc2 is coordinated through a SUMO interaction motif.", "journal": "Molecular and cellular biology", "date": "2010", "authors": "Yang SH, Sharrocks AD", "reference": { "type": "PubMed", "id": "20176810", "url": "https://pubmed.ncbi.nlm.nih.gov/20176810" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UER7-1", "protein_name": "Death domain-associated protein 6", "gene_name": "DAXX", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92793-1", "protein_name": "CREB-binding protein", "gene_name": "CREBBP", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15596-1", "protein_name": "Nuclear receptor coactivator 2", "gene_name": "NCOA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99497-1", 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helicase DDX5", "gene_name": "DDX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H2X6-1", "protein_name": "Homeodomain-interacting protein kinase 2", "gene_name": "HIPK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96ST3-1", "protein_name": "Paired amphipathic helix protein Sin3a", "gene_name": "SIN3A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9H160-1", "protein_name": "Inhibitor of growth protein 2", "gene_name": "ING2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P06748-1", "protein_name": "Nucleophosmin", "gene_name": "NPM1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P48552-1", "protein_name": "Nuclear receptor-interacting protein 1", "gene_name": "NRIP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q09472-1", "protein_name": "Histone acetyltransferase p300", "gene_name": "EP300", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13363-1", "protein_name": "C-terminal-binding protein 1", "gene_name": "CTBP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBK2-1", "protein_name": "Peroxisome proliferator-activated receptor gamma coactivator 1-alpha", "gene_name": "PPARGC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9GZX5-1", "protein_name": "Zinc finger protein 350", "gene_name": "ZNF350", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UIS9-1", "protein_name": "Methyl-CpG-binding domain protein 1", "gene_name": "MBD1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKL3-1", "protein_name": "CASP8-associated protein 2", "gene_name": "CASP8AP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P52739-1", "protein_name": "Zinc finger protein 131", "gene_name": "ZNF131", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96PU4-1", "protein_name": "E3 ubiquitin-protein ligase UHRF2", "gene_name": "UHRF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15788-1", "protein_name": "Nuclear receptor coactivator 1", "gene_name": "NCOA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15424-1", "protein_name": "Scaffold attachment factor B1", "gene_name": "SAFB", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20176810", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 42 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMOylation-dependent localization of IKKepsilon in PML nuclear bodies is essential for protection against DNA-damage-triggered cell death.", "journal": "Molecular cell", "date": "2010", "authors": "Renner F, Moreno R, Schmitz ML", "reference": { "type": "PubMed", "id": "20188669", "url": "https://pubmed.ncbi.nlm.nih.gov/20188669" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14164-1", "protein_name": "Inhibitor of nuclear factor kappa-B kinase subunit epsilon", "gene_name": "IKBKE", "tax_name": "Human" }, { "uniprot_canonical_ac": "P25963-1", "protein_name": "NF-kappa-B inhibitor alpha", "gene_name": "NFKBIA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00653-1", "protein_name": "Nuclear factor NF-kappa-B p100 subunit", "gene_name": "NFKB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NS56-1", "protein_name": "E3 ubiquitin-protein ligase Topors", "gene_name": "TOPORS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19525-1", "protein_name": "Interferon-induced, double-stranded RNA-activated protein kinase", "gene_name": "EIF2AK2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6K9-1", "protein_name": "NF-kappa-B essential modulator", "gene_name": "IKBKG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q04206-1", "protein_name": "Transcription factor p65", "gene_name": "RELA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 231, "end_pos": 231, "sequence_org": "K", "sequence_mut": "R", "comment": "Loss of sumoylation and loss of targeting to nuclear bodies.", "evidence": [ { "database": "UniProtKB", "id": "Q14164", "url": "https://www.uniprot.org/uniprotkb/Q14164" }, { "database": "PubMed", "id": "20188669", "url": "https://pubmed.ncbi.nlm.nih.gov/20188669" } ], "uniprot_canonical_ac": "Q14164-1" } ], "record_id": "pubmed.20188669", "abstract": "", "glycosylation": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 12 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The putative nuclear localization signal of the human RAD52 protein is a potential sumoylation site.", "journal": "Journal of biochemistry", "date": "2010", "authors": "Saito K, Kagawa W, Suzuki T, Suzuki H, Yokoyama S, Saitoh H, Tashiro S, Dohmae N, Kurumizaka H", "reference": { "type": "PubMed", "id": "20190268", "url": "https://pubmed.ncbi.nlm.nih.gov/20190268" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13569-1", "protein_name": "G/T mismatch-specific thymine DNA glycosylase", "gene_name": "TDG", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96SB8-1", "protein_name": "Structural maintenance of chromosomes protein 6", "gene_name": "SMC6", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NXX6-1", "protein_name": "Non-structural maintenance of chromosomes element 4 homolog A", "gene_name": "NSMCE4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N3U4-1", "protein_name": "Cohesin subunit SA-2", "gene_name": "STAG2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WVM7-1", "protein_name": "Cohesin subunit SA-1", "gene_name": "STAG1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IY18-1", "protein_name": "Structural maintenance of chromosomes protein 5", "gene_name": "SMC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14683-1", "protein_name": "Structural maintenance of chromosomes protein 1A", "gene_name": "SMC1A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14676-1", "protein_name": "Mediator of DNA damage checkpoint protein 1", "gene_name": "MDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54132-1", "protein_name": "RecQ-like DNA helicase BLM", "gene_name": "BLM", "tax_name": "Human" }, { 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"tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "O60216-1", "protein_name": "Double-strand-break repair protein rad21 homolog", "gene_name": "RAD21", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IYW5-1", "protein_name": "E3 ubiquitin-protein ligase RNF168", "gene_name": "RNF168", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "P43351-1", "protein_name": "DNA repair protein RAD52 homolog", "gene_name": "RAD52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "O95714-1", "protein_name": "E3 ubiquitin-protein ligase HERC2", "gene_name": "HERC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UQE7-1", "protein_name": "Structural maintenance of chromosomes protein 3", "gene_name": "SMC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96MG7-1", "protein_name": "Non-structural maintenance of chromosomes element 3 homolog", "gene_name": "NSMCE3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N140-1", "protein_name": "EP300-interacting inhibitor of differentiation 3", "gene_name": "EID3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "P38398-1", "protein_name": "Breast cancer type 1 susceptibility protein", "gene_name": "BRCA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20190268", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 72 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "The forkhead transcription factor Foxl2 is sumoylated in both human and mouse: sumoylation affects its stability, localization, and activity.", "journal": "PloS one", "date": "2010", "authors": "Marongiu M, Deiana M, Meloni A, Marcia L, Puddu A, Cao A, Schlessinger D, Crisponi L", "reference": { "type": "PubMed", "id": "20209145", "url": "https://pubmed.ncbi.nlm.nih.gov/20209145" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92481-1", "protein_name": "Transcription factor AP-2-beta", "gene_name": "TFAP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13330-1", "protein_name": "Metastasis-associated protein MTA1", "gene_name": "MTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92754-1", "protein_name": "Transcription factor AP-2 gamma", "gene_name": "TFAP2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14526-1", "protein_name": "Hypermethylated in cancer 1 protein", "gene_name": "HIC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75030-1", "protein_name": "Microphthalmia-associated transcription factor", "gene_name": "MITF", "tax_name": "Human" }, { "uniprot_canonical_ac": "P42771-1", "protein_name": "Cyclin-dependent kinase inhibitor 2A", "gene_name": "CDKN2A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P58012-1", "protein_name": "Forkhead box protein L2", "gene_name": "FOXL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12888-1", "protein_name": "TP53-binding protein 1", "gene_name": "TP53BP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N2W9-1", "protein_name": "E3 SUMO-protein ligase PIAS4", "gene_name": "PIAS4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q02447-1", "protein_name": "Transcription factor Sp3", "gene_name": "SP3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q00987-1", "protein_name": "E3 ubiquitin-protein ligase Mdm2", "gene_name": "MDM2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P04637-1", "protein_name": "Cellular tumor antigen p53", "gene_name": "TP53", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Phosphorylation-dependent interaction of SATB1 and PIAS1 directs SUMO-regulated caspase cleavage of SATB1.", "journal": "Molecular and cellular biology", "date": "2010", "authors": "Tan JA, Song J, Chen Y, 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"uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01826-1", "protein_name": "DNA-binding protein SATB1", "gene_name": "SATB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96006-1", "protein_name": "E3 SUMO-protein ligase ZBED1", "gene_name": "ZBED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8IXK0-1", "protein_name": "Polyhomeotic-like protein 2", "gene_name": "PHC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P45973-1", "protein_name": "Chromobox protein homolog 5", "gene_name": "CBX5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49790-1", "protein_name": "Nuclear pore complex protein Nup153", "gene_name": "NUP153", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12769-1", "protein_name": "Nuclear pore complex protein Nup160", "gene_name": "NUP160", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q12873-1", "protein_name": "ATP-dependent chromatin remodeler CHD3", "gene_name": "CHD3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92769-1", "protein_name": "Histone deacetylase 2", "gene_name": "HDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 ubiquitin-protein ligase RING1", "gene_name": "RING1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99567-1", "protein_name": "Nuclear pore complex protein Nup88", "gene_name": "NUP88", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UPW6-1", "protein_name": "DNA-binding protein SATB2", "gene_name": "SATB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78406-1", "protein_name": "mRNA export factor RAE1", "gene_name": "RAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH4-1", "protein_name": "Nucleoporin Nup37", "gene_name": "NUP37", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8N1F7-1", "protein_name": "Nuclear pore complex protein Nup93", "gene_name": "NUP93", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35227-1", "protein_name": "Polycomb group RING finger protein 2", "gene_name": "PCGF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q7Z3B4-1", "protein_name": "Nucleoporin p54", "gene_name": "NUP54", "tax_name": "Human" }, { "uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "phosphorylation": [ { "start_pos": 188, "end_pos": 188, "kinase_uniprot_canonical_ac": "", "kinase_gene_name": "", "residue": "Thr", "comment": "", "evidence": [ { "database": "iPTMnet", "id": "Q01826", "url": "http://research.bioinformatics.udel.edu/iptmnet/entry/Q01826" }, { "database": "PubMed", "id": "20351170", "url": "https://pubmed.ncbi.nlm.nih.gov/20351170" } ], "site_lbl": "Thr188", "uniprot_canonical_ac": "Q01826-1" } ], "record_id": "pubmed.20351170", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 53 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl", "uniprot_canonical_ac" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "DDB2 complex-mediated ubiquitylation around DNA damage is oppositely regulated by XPC and Ku and contributes to the recruitment of XPA.", "journal": "Molecular and cellular biology", "date": "2010", "authors": "Takedachi A, Saijo M, Tanaka K", "reference": { "type": "PubMed", "id": "20368362", "url": "https://pubmed.ncbi.nlm.nih.gov/20368362" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54727-1", "protein_name": "Lysine-specific demethylase RAD23B", "gene_name": "RAD23B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13888-1", "protein_name": "General transcription factor IIH subunit 2", "gene_name": "GTF2H2C_2; GTF2H2C; GTF2H2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92759-1", "protein_name": "General transcription factor IIH subunit 4", "gene_name": "GTF2H4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P19447-1", "protein_name": "General transcription and DNA repair factor IIH helicase/translocase subunit XPB", "gene_name": "ERCC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P28715-1", "protein_name": "DNA excision repair protein ERCC-5", "gene_name": "ERCC5", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UGN5-1", "protein_name": "Poly [ADP-ribose] polymerase 2", "gene_name": "PARP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZYL4-1", "protein_name": "General transcription factor IIH subunit 5", "gene_name": "GTF2H5", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35244-1", "protein_name": "Replication protein A 14 kDa subunit", "gene_name": "RPA3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P07992-1", "protein_name": "DNA excision repair protein ERCC-1", "gene_name": "ERCC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q16531-1", "protein_name": "DNA damage-binding protein 1", "gene_name": "DDB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P27694-1", "protein_name": "Replication protein A 70 kDa DNA-binding subunit", "gene_name": "RPA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P41208-1", "protein_name": "Centrin-2", "gene_name": "CETN2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01831-1", "protein_name": "DNA repair protein complementing XP-C cells", "gene_name": "XPC", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q86WJ1-1", "protein_name": "ATP-dependent chromatin remodeler CHD1L", "gene_name": "CHD1L", "tax_name": "Human" }, { "uniprot_canonical_ac": "P32780-1", "protein_name": "General transcription factor IIH subunit 1", "gene_name": "GTF2H1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13889-1", "protein_name": "General transcription factor IIH subunit 3", "gene_name": "GTF2H3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92466-1", "protein_name": "DNA damage-binding protein 2", "gene_name": "DDB2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62877-1", "protein_name": "E3 ubiquitin-protein ligase RBX1", "gene_name": "RBX1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P18074-1", "protein_name": "General transcription and DNA repair factor IIH helicase subunit XPD", "gene_name": "ERCC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51948-1", "protein_name": "CDK-activating kinase assembly factor MAT1", "gene_name": "MNAT1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P51946-1", "protein_name": "Cyclin-H", "gene_name": "CCNH", "tax_name": "Human" }, { "uniprot_canonical_ac": "P15927-1", "protein_name": "Replication protein A 32 kDa subunit", "gene_name": "RPA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63279-1", "protein_name": "SUMO-conjugating enzyme UBC9", "gene_name": "UBE2I", "tax_name": "Human" }, { "uniprot_canonical_ac": "P54725-1", "protein_name": "Lysine-specific demethylase RAD23A", "gene_name": "RAD23A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P09874-1", "protein_name": "Poly [ADP-ribose] polymerase 1", "gene_name": "PARP1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62979-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "RPS27A", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61088-1", "protein_name": "Ubiquitin-conjugating enzyme E2 N", "gene_name": "UBE2N", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q6ZNA4-1", "protein_name": "E3 ubiquitin-protein ligase Arkadia", "gene_name": "RNF111", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13619-1", "protein_name": "Cullin-4A", "gene_name": "CUL4A", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13620-2", "protein_name": "Cullin-4B", "gene_name": "CUL4B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15819-1", "protein_name": "Ubiquitin-conjugating enzyme E2 variant 2", "gene_name": "UBE2V2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q70EL2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 45", "gene_name": "USP45", "tax_name": "Human" }, { "uniprot_canonical_ac": "P50613-1", "protein_name": "Cyclin-dependent kinase 7", "gene_name": "CDK7", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG47-1", "protein_name": "Polyubiquitin-B", "gene_name": "UBB", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62987-1", "protein_name": "Ubiquitin-ribosomal protein eL40 fusion protein", "gene_name": "UBA52", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92889-1", "protein_name": "DNA repair endonuclease XPF", "gene_name": "ERCC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P23025-1", "protein_name": "DNA repair protein complementing XP-A cells", "gene_name": "XPA", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6X2-1", "protein_name": "E3 SUMO-protein ligase PIAS3", "gene_name": "PIAS3", "tax_name": "Human" }, { "uniprot_canonical_ac": "P0CG48-1", "protein_name": "Polyubiquitin-C", "gene_name": "UBC", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20368362", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 43 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development.", "journal": "Molecular cell", "date": "2010", "authors": "Kang X, Qi Y, Zuo Y, Wang Q, Zou Y, Schwartz RJ, Cheng J, Yeh ET", "reference": { "type": "PubMed", "id": "20417598", "url": "https://pubmed.ncbi.nlm.nih.gov/20417598" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q969R5-1", "protein_name": "Lethal(3)malignant brain tumor-like protein 2", "gene_name": "L3MBTL2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9HC52-1", "protein_name": "Chromobox protein homolog 8", "gene_name": "CBX8", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13547-1", "protein_name": "Histone deacetylase 1", "gene_name": "HDAC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "A8CG34-1", "protein_name": "Nuclear envelope pore membrane protein POM 121C", "gene_name": "POM121C", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35658-1", "protein_name": "Nuclear pore complex protein Nup214", "gene_name": "NUP214", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q5SRE5-1", "protein_name": "Nucleoporin NUP188", "gene_name": "NUP188", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BW27-1", "protein_name": "Nuclear pore complex protein Nup85", "gene_name": "NUP85", "tax_name": "Human" }, { "uniprot_canonical_ac": "O15504-1", "protein_name": "Nucleoporin NUP42", "gene_name": "NUP42", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UKX7-1", "protein_name": "Nuclear pore complex protein Nup50", "gene_name": "NUP50", "tax_name": "Human" }, { "uniprot_canonical_ac": "P57740-1", "protein_name": "Nuclear pore complex protein Nup107", "gene_name": "NUP107", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NDX5-1", "protein_name": "Polyhomeotic-like protein 3", "gene_name": "PHC3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8WUM0-1", "protein_name": "Nuclear pore complex protein Nup133", "gene_name": "NUP133", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9BTX1-1", "protein_name": "Nucleoporin NDC1", "gene_name": "NDC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH3-1", "protein_name": "Nucleoporin Nup43", "gene_name": "NUP43", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8TEM1-1", "protein_name": "Nuclear pore membrane glycoprotein 210", "gene_name": "NUP210", "tax_name": "Human" }, { "uniprot_canonical_ac": "P55735-1", "protein_name": "Protein SEC13 homolog", "gene_name": "SEC13", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75694-1", "protein_name": "Nuclear pore complex protein Nup155", "gene_name": "NUP155", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14781-1", "protein_name": "Chromobox protein homolog 2", "gene_name": "CBX2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q01826-1", "protein_name": "DNA-binding protein SATB1", "gene_name": "SATB1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q8NFH5-1", "protein_name": "Nucleoporin NUP35", "gene_name": "NUP35", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q96HA1-1", "protein_name": "Nuclear envelope pore membrane protein POM 121", "gene_name": "POM121", "tax_name": "Human" }, { "uniprot_canonical_ac": "O96006-1", "protein_name": "E3 SUMO-protein ligase ZBED1", "gene_name": "ZBED1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P62805-1", "protein_name": "Histone H4", "gene_name": "H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C1; 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"Human" }, { "uniprot_canonical_ac": "P49792-1", "protein_name": "E3 SUMO-protein ligase RanBP2", "gene_name": "RANBP2", "tax_name": "Human" }, { "uniprot_canonical_ac": "O75925-1", "protein_name": "E3 SUMO-protein ligase PIAS1", "gene_name": "PIAS1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92769-1", "protein_name": "Histone deacetylase 2", "gene_name": "HDAC2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P35226-1", "protein_name": "Polycomb complex protein BMI-1", "gene_name": "BMI1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P78364-1", "protein_name": "Polyhomeotic-like protein 1", "gene_name": "PHC1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q99496-1", "protein_name": "E3 ubiquitin-protein ligase RING2", "gene_name": "RNF2", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q06587-1", "protein_name": "E3 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"uniprot_canonical_ac": "P12270-1", "protein_name": "Nucleoprotein TPR", "gene_name": "TPR", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q15022-1", "protein_name": "Polycomb protein SUZ12", "gene_name": "SUZ12", "tax_name": "Human" }, { "uniprot_canonical_ac": "P56524-1", "protein_name": "Histone deacetylase 4", "gene_name": "HDAC4", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9NRG9-1", "protein_name": "Aladin", "gene_name": "AAAS", "tax_name": "Human" }, { "uniprot_canonical_ac": "O00257-1", "protein_name": "E3 SUMO-protein ligase CBX4", "gene_name": "CBX4", "tax_name": "Human" }, { "uniprot_canonical_ac": "P37198-1", "protein_name": "Nuclear pore glycoprotein p62", "gene_name": "NUP62", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], 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"https://pubmed.ncbi.nlm.nih.gov/20501649" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBE0-1", "protein_name": "SUMO-activating enzyme subunit 1", "gene_name": "SAE1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q9UBT2-1", "protein_name": "SUMO-activating enzyme subunit 2", "gene_name": "UBA2", "tax_name": "Human" }, { "uniprot_canonical_ac": "P63165-1", "protein_name": "Small ubiquitin-related modifier 1", "gene_name": "SUMO1", "tax_name": "Human" }, { "uniprot_canonical_ac": "P61956-1", "protein_name": "Small ubiquitin-related modifier 2", "gene_name": "SUMO2", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "P55854", "url": "https://www.uniprot.org/uniprotkb/P55854" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.20501649", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": "referenced_glycans", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Differential regulation of HIC1 target genes by CtBP and NuRD, via an acetylation/SUMOylation switch, in quiescent versus proliferating cells.", "journal": "Molecular and cellular biology", "date": "2010", "authors": "Van Rechem C, Boulay G, Pinte S, Stankovic-Valentin N, Guerardel C, Leprince D", "reference": { "type": "PubMed", "id": "20547755", "url": "https://pubmed.ncbi.nlm.nih.gov/20547755" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "P55854-1", "protein_name": "Small ubiquitin-related modifier 3", "gene_name": "SUMO3", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92481-1", "protein_name": "Transcription factor AP-2-beta", "gene_name": "TFAP2B", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q13330-1", "protein_name": "Metastasis-associated protein MTA1", "gene_name": "MTA1", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q92754-1", "protein_name": "Transcription factor AP-2 gamma", "gene_name": "TFAP2C", "tax_name": "Human" }, { "uniprot_canonical_ac": "Q14526-1", "protein_name": "Hypermethylated in cancer 1 protein", "gene_name": "HIC1", "tax_name": "Human" }, { 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"mutagenesis": [ { "start_pos": 333, "end_pos": 333, "sequence_org": "K", "sequence_mut": "Q", "comment": "Mimicks acetylation. Impairs interaction with RBBP4 and MTA1 and no effect on interaction with CTBP2. Reduces transcriptional repression.", "evidence": [ { "database": "UniProtKB", "id": "Q14526", "url": "https://www.uniprot.org/uniprotkb/Q14526" }, { "database": "PubMed", "id": "17283066", "url": "https://pubmed.ncbi.nlm.nih.gov/17283066" }, { "database": "PubMed", "id": "20547755", "url": "https://pubmed.ncbi.nlm.nih.gov/20547755" } ], "uniprot_canonical_ac": "Q14526-1" }, { "start_pos": 333, "end_pos": 333, "sequence_org": "K", "sequence_mut": "R", "comment": "Abolishes sumoylation; impairs transcriptional repression activity.", "evidence": [ { "database": "UniProtKB", "id": "Q14526", "url": "https://www.uniprot.org/uniprotkb/Q14526" }, { "database": "PubMed", "id": "20547755", "url": "https://pubmed.ncbi.nlm.nih.gov/20547755" }, { "database": "PubMed", "id": "17283066", "url": "https://pubmed.ncbi.nlm.nih.gov/17283066" } ], "uniprot_canonical_ac": "Q14526-1" }, { "start_pos": 335, "end_pos": 335, "sequence_org": "E", "sequence_mut": "A", "comment": "Impairs transcriptional repression activity. Decreases interaction with MTA1.", "evidence": [ { "database": "UniProtKB", "id": "Q14526", "url": "https://www.uniprot.org/uniprotkb/Q14526" }, { "database": "PubMed", "id": "20547755", "url": "https://pubmed.ncbi.nlm.nih.gov/20547755" }, { "database": "PubMed", "id": "17283066", "url": "https://pubmed.ncbi.nlm.nih.gov/17283066" } ], "uniprot_canonical_ac": "Q14526-1" }, { "start_pos": 336, "end_pos": 336, "sequence_org": "P", "sequence_mut": "A", "comment": "Impairs K-333 acetylation; no effect on sumoylation. 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