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J. Biochem.", "date": "1994", "authors": "Kitamura A, Takahashi K, Okajima A, Kitamura N", "reference": { "type": "PubMed", "id": "7925411", "url": "https://pubmed.ncbi.nlm.nih.gov/7925411" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q8TCB0-1", "protein_name": "Interferon-induced protein 44", "gene_name": "IFI44", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q8TCB0", "url": "https://www.uniprot.org/uniprotkb/Q8TCB0" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.7925411", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"gene_name": "IL17RA", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q96PD4", "url": "https://www.uniprot.org/uniprotkb/Q96PD4" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "mutagenesis": [ { "start_pos": 77, "end_pos": 77, "sequence_org": "R", "sequence_mut": "A", "comment": "Significantly decreases the affinity for IL17RA and IL17RC by nearly 5-fold and 200-fold, respectively.", "evidence": [ { "database": "UniProtKB", "id": "Q96PD4", "url": "https://www.uniprot.org/uniprotkb/Q96PD4" }, { "database": "PubMed", "id": "28827714", "url": "https://pubmed.ncbi.nlm.nih.gov/28827714" } ], "uniprot_canonical_ac": "Q96PD4-1" }, { "start_pos": 69, "end_pos": 69, "sequence_org": "R", "sequence_mut": "A", "comment": "Impairs binding to IL17RA and IL17RC.", "evidence": [ { "database": "UniProtKB", "id": "Q16552", "url": "https://www.uniprot.org/uniprotkb/Q16552" 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[] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Structural Analysis Reveals that the Cytokine IL-17F Forms a Homodimeric Complex with Receptor 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Med.", "date": "2019", "authors": "Tran Mau-Them F, Guibaud L, Duplomb L, Keren B, Lindstrom K, Marey I, Mochel F, van den Boogaard MJ, Oegema R, Nava C, Masurel A, Jouan T, Jansen FE, Au M, Chen AH, Cho M, Duffourd Y, Lozier E, Konovalov F, Sharkov A, Korostelev S, Urteaga B, Dickson P, Vera M, Martinez-Agosto JA, Begemann A, Zweier M, Schmitt-Mechelke T, Rauch A, Philippe C, van Gassen K, Nelson S, Graham JM Jr, Friedman J, Faivre L, Lin HJ, Thauvin-Robinet C, Vitobello A", "reference": { "type": "PubMed", "id": "30166628", "url": "https://pubmed.ncbi.nlm.nih.gov/30166628" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H1B7-1", "protein_name": "Probable E3 ubiquitin-protein ligase IRF2BPL", "gene_name": "IRF2BPL", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H1B7", "url": "https://www.uniprot.org/uniprotkb/Q9H1B7" } ], "common_name": "Human", "glygen_name": "Human", 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"2022", "authors": "Antonelli F, Grieco G, Cavallieri F, Casella A, Valente EM", "reference": { "type": "PubMed", "id": "34864472", "url": "https://pubmed.ncbi.nlm.nih.gov/34864472" }, "referenced_glycans": [], "referenced_proteins": [ { "uniprot_canonical_ac": "Q9H1B7-1", "protein_name": "Probable E3 ubiquitin-protein ligase IRF2BPL", "gene_name": "IRF2BPL", "tax_name": "Human" } ], "species": [ { "name": "Homo sapiens", "taxid": 9606, "evidence": [ { "database": "UniProtKB", "id": "Q9H1B7", "url": "https://www.uniprot.org/uniprotkb/Q9H1B7" } ], "common_name": "Human", "glygen_name": "Human", "reference_species": "Homo sapiens [9606]" } ], "record_id": "pubmed.34864472", "abstract": "", "glycosylation": [], "mutagenesis": [], "snv": [], "phosphorylation": [], "glycation": [], "section_stats": [ { "table_id": "referenced_proteins", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "uniprot_canonical_ac", "protein_name", "gene_name", "tax_name" ] }, { "table_id": 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"count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 } ], "sort_fields": [] } ] }, { "title": "Identification and gene organization of three novel members of the IL-1 family on human chromosome 2.", "journal": "Genomics", "date": "2000", "authors": "Busfield S J, Comrack C A, Yu G, Chickering T W, Smutko J S, Zhou H, Leiby K R, Holmgren L M, Gearing D P, Pan Y", "reference": { "type": "PubMed", "id": "10860666", "url": "https://pubmed.ncbi.nlm.nih.gov/10860666" }, "referenced_glycans": [], 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